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<meta name="keywords" content="C0151934, decreased sense of taste, decreased taste, decreased taste sensation, finding, hypogeusia, hypogeusias, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A decreased ability to perceive flavor." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
UID=57498
ConceptID=C0151934
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Hypogeusia</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>57498</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0151934</a></dd><dt><span class="dotprefix"></span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
<td>Hypogeusias</td></tr>
<tr><td><span class="bold">SNOMED CT: </span></td>
<td>Decreased sense of taste (697990000); Hypogeusia (697990000)</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0000224">HP:0000224</a></td></tr>
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">A decreased ability to perceive flavor. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
</div>
<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Hypogeusia</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867438" ref="tree=MeSH" title="MedGen record for Abnormality of the head">Abnormality of the head</a></span><ul><li><span class="TLline"><a href="/medgen/871375" ref="tree=MeSH" title="MedGen record for Abnormality of the face">Abnormality of the face</a></span><ul><li><span class="TLline"><a href="/medgen/6447" ref="tree=MeSH" title="MedGen record for Abnormality of the mouth">Abnormality of the mouth</a></span><ul><li><span class="TLline"><a href="/medgen/1631824" ref="tree=MeSH" title="MedGen record for Abnormal oral physiology">Abnormal oral physiology</a></span><ul><li><span class="TLline"><a href="/medgen/907476" ref="tree=MeSH" title="MedGen record for Abnormal tongue physiology">Abnormal tongue physiology</a></span><ul><li><span class="TLline"><a href="/medgen/871383" ref="tree=MeSH" title="MedGen record for Abnormality of taste sensation">Abnormality of taste sensation</a></span><ul><li><span class="matched_ds">Hypogeusia</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_112">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln clinfeat">
<div class="divPopper rprt" id="rdis_41678"><div><strong>Familial dysautonomia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>41678</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information."><span class="highlight" style="background-color:">C0013364</span></a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Familial dysautonomia, which affects the development and survival of sensory, sympathetic, and parasympathetic neurons, is a debilitating disorder present from birth. Neuronal degeneration progresses throughout life. Affected individuals have gastrointestinal dysfunction, autonomic crises (i.e., hypertensive vomiting attacks), recurrent pneumonia, altered pain sensitivity, altered temperature perception, and blood pressure instability. Hypotonia contributes to delay in acquisition of motor milestones. Optic neuropathy results in progressive vision loss. Older individuals often have a broad-based and ataxic gait that deteriorates over time. Developmental delay / intellectual disability occur in about 21% of individuals. Life expectancy is decreased.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/41678">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_66355"><div><strong>Hereditary acrodermatitis enteropathica</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>66355</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0221036</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Acrodermatitis enteropathica of the zinc deficiency type (AEZ) is characterized by intermittent simultaneous occurrence of diarrhea and dermatitis with failure to thrive. Alopecia of the scalp, eyebrows, and eyelashes is a usual feature. The skin lesions are bullous. Noteworthy is the cure by diodoquin, or diiodohydroxyquinoline (Dillaha et al., 1953; Bloom and Sobel, 1955). Rodin and Goldman (1969) described autopsy findings, including pancreatic islet hyperplasia, absence of the thymus and of germinal centers, and plasmocytosis of lymph nodes and spleen.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/66355">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_416701"><div><strong>Neuropathy, hereditary sensory and autonomic, type 2A</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>416701</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C2752089</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Hereditary sensory and autonomic neuropathy type II (HSAN2) is characterized by progressively reduced sensation to pain, temperature, and touch. Onset can be at birth and is often before puberty. The sensory deficit is predominantly distal with the lower limbs more severely affected than the upper limbs. Over time sensory function becomes severely reduced. Unnoticed injuries and neuropathic skin promote ulcerations and infections that result in spontaneous amputation of digits or the need for surgical amputation. Osteomyelitis is common. Painless fractures can complicate the disease. Autonomic disturbances are variable and can include hyperhidrosis, tonic pupils, and urinary incontinence in those with more advanced disease.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/416701">Condition Record</a></div></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_41678" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial dysautonomia</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_66355" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hereditary acrodermatitis enteropathica</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_416701" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Neuropathy, hereditary sensory and autonomic, type 2A</a></div></div>
</div>
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<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
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<div class="portlet_content ln"><span class="medgenPMauthor">Hasan AZ,
Preethi BL,
Kalra P</span><br />
<span class="medgenPMjournal">Ghana Med J</span>
2023 Dec;57(4):270-274.
doi: 10.4314/gmj.v57i4.3.
<span class="bold">PMID: </span><a href="/pubmed/38957847" target="_blank">38957847</a><a href="/pmc/articles/PMC11215226" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37678663">Safety and efficacy of P2X3 receptor antagonist for the treatment of refractory or unexplained chronic cough: A systematic review and meta-analysis of 11 randomized controlled trials.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ramadan A,
El-Samahy M,
Elrosasy A,
Al-Tawil M,
Abdelaziz A,
Soliman MA,
Abouzid M</span><br />
<span class="medgenPMjournal">Pulm Pharmacol Ther</span>
2023 Dec;83:102252.
Epub 2023 Sep 9
doi: 10.1016/j.pupt.2023.102252.
<span class="bold">PMID: </span><a href="/pubmed/37678663" target="_blank">37678663</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33635172">Presentation and management of anxiety in individuals with acute symptomatic or asymptomatic COVID-19 infection, and in the post-COVID-19 recovery phase.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Uzunova G,
Pallanti S,
Hollander E</span><br />
<span class="medgenPMjournal">Int J Psychiatry Clin Pract</span>
2021 Jun;25(2):115-131.
Epub 2021 Feb 26
doi: 10.1080/13651501.2021.1887264.
<span class="bold">PMID: </span><a href="/pubmed/33635172" target="_blank">33635172</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22hypogeusia%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (6)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/37197770">Efficacy and safety of gefapixant for chronic cough: a meta-analysis of randomised controlled trials.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Chuang MH,
Chen IW,
Chen JY,
Kang FC,
Ho CN,
Wu SC,
Yew M,
Lan KM,
Hung KC</span><br />
<span class="medgenPMjournal">Eur Respir Rev</span>
2023 Jun 30;32(168)
Epub 2023 May 17
doi: 10.1183/16000617.0219-2022.
<span class="bold">PMID: </span><a href="/pubmed/37197770" target="_blank">37197770</a><a href="/pmc/articles/PMC10189640" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35248186">Efficacy and safety of gefapixant, a P2X(3) receptor antagonist, in refractory chronic cough and unexplained chronic cough (COUGH-1 and COUGH-2): results from two double-blind, randomised, parallel-group, placebo-controlled, phase 3 trials.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">McGarvey LP,
Birring SS,
Morice AH,
Dicpinigaitis PV,
Pavord ID,
Schelfhout J,
Nguyen AM,
Li Q,
Tzontcheva A,
Iskold B,
Green SA,
Rosa C,
Muccino DR,
Smith JA;
COUGH-1 and COUGH-2 Investigators</span><br />
<span class="medgenPMjournal">Lancet</span>
2022 Mar 5;399(10328):909-923.
doi: 10.1016/S0140-6736(21)02348-5.
<span class="bold">PMID: </span><a href="/pubmed/35248186" target="_blank">35248186</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33232965">Skin Manifestations Associated with COVID-19: Current Knowledge and Future Perspectives.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Genovese G,
Moltrasio C,
Berti E,
Marzano AV</span><br />
<span class="medgenPMjournal">Dermatology</span>
2021;237(1):1-12.
Epub 2020 Nov 24
doi: 10.1159/000512932.
<span class="bold">PMID: </span><a href="/pubmed/33232965" target="_blank">33232965</a><a href="/pmc/articles/PMC7801998" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32770653">Screening and testing for COVID-19 before surgery.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kovoor JG,
Tivey DR,
Williamson P,
Tan L,
Kopunic HS,
Babidge WJ,
Collinson TG,
Hewett PJ,
Hugh TJ,
Padbury RTA,
Frydenberg M,
Douglas RG,
Kok J,
Maddern GJ</span><br />
<span class="medgenPMjournal">ANZ J Surg</span>
2020 Oct;90(10):1845-1856.
Epub 2020 Sep 23
doi: 10.1111/ans.16260.
<span class="bold">PMID: </span><a href="/pubmed/32770653" target="_blank">32770653</a><a href="/pmc/articles/PMC7436563" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29260510">Interventions for managing taste disturbances.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kumbargere Nagraj S,
George RP,
Shetty N,
Levenson D,
Ferraiolo DM,
Shrestha A</span><br />
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
2017 Dec 20;12(12):CD010470.
doi: 10.1002/14651858.CD010470.pub3.
<span class="bold">PMID: </span><a href="/pubmed/29260510" target="_blank">29260510</a><a href="/pmc/articles/PMC6486004" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypogeusia%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (122)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/35248186">Efficacy and safety of gefapixant, a P2X(3) receptor antagonist, in refractory chronic cough and unexplained chronic cough (COUGH-1 and COUGH-2): results from two double-blind, randomised, parallel-group, placebo-controlled, phase 3 trials.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">McGarvey LP,
Birring SS,
Morice AH,
Dicpinigaitis PV,
Pavord ID,
Schelfhout J,
Nguyen AM,
Li Q,
Tzontcheva A,
Iskold B,
Green SA,
Rosa C,
Muccino DR,
Smith JA;
COUGH-1 and COUGH-2 Investigators</span><br />
<span class="medgenPMjournal">Lancet</span>
2022 Mar 5;399(10328):909-923.
doi: 10.1016/S0140-6736(21)02348-5.
<span class="bold">PMID: </span><a href="/pubmed/35248186" target="_blank">35248186</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34289037">Emerging neurotropic features of SARS-CoV-2.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Zhan WR,
Huang J,
Zeng PM,
Tian WY,
Luo ZG</span><br />
<span class="medgenPMjournal">J Mol Cell Biol</span>
2021 Dec 30;13(10):705-711.
doi: 10.1093/jmcb/mjab044.
<span class="bold">PMID: </span><a href="/pubmed/34289037" target="_blank">34289037</a><a href="/pmc/articles/PMC8344859" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33534829">Covid-19 in outpatients-Is fever a useful indicator for SARS-CoV-2 infection?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Schneider A,
Kirsten H,
Lordick F,
Lordick F,
Lübbert C,
von Braun A</span><br />
<span class="medgenPMjournal">PLoS One</span>
2021;16(2):e0246312.
Epub 2021 Feb 3
doi: 10.1371/journal.pone.0246312.
<span class="bold">PMID: </span><a href="/pubmed/33534829" target="_blank">33534829</a><a href="/pmc/articles/PMC7857607" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/16733342">Postoperative/posttraumatic gustatory dysfunction.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Landis BN,
Lacroix JS</span><br />
<span class="medgenPMjournal">Adv Otorhinolaryngol</span>
2006;63:242-254.
doi: 10.1159/000093763.
<span class="bold">PMID: </span><a href="/pubmed/16733342" target="_blank">16733342</a></div>
<div class="nl"><a target="_blank" href="/pubmed/4256153">Subclinical pellagra and idiopathic hypogeusia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Green RF</span><br />
<span class="medgenPMjournal">JAMA</span>
1971 Nov 22;218(8):1303.
<span class="bold">PMID: </span><a href="/pubmed/4256153" target="_blank">4256153</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypogeusia%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (140)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/35248186">Efficacy and safety of gefapixant, a P2X(3) receptor antagonist, in refractory chronic cough and unexplained chronic cough (COUGH-1 and COUGH-2): results from two double-blind, randomised, parallel-group, placebo-controlled, phase 3 trials.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">McGarvey LP,
Birring SS,
Morice AH,
Dicpinigaitis PV,
Pavord ID,
Schelfhout J,
Nguyen AM,
Li Q,
Tzontcheva A,
Iskold B,
Green SA,
Rosa C,
Muccino DR,
Smith JA;
COUGH-1 and COUGH-2 Investigators</span><br />
<span class="medgenPMjournal">Lancet</span>
2022 Mar 5;399(10328):909-923.
doi: 10.1016/S0140-6736(21)02348-5.
<span class="bold">PMID: </span><a href="/pubmed/35248186" target="_blank">35248186</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27734822">The side-effects of head and neck tumors radiotherapy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Skiba-Tatarska M,
Kusa-Podkańska M,
Surtel A,
Wysokińska-Miszczuk J</span><br />
<span class="medgenPMjournal">Pol Merkur Lekarski</span>
2016 Jul 29;41(241):47-49.
<span class="bold">PMID: </span><a href="/pubmed/27734822" target="_blank">27734822</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23210698">Iatrogenic Cushing's syndrome and topical steroid therapy: case series and review of the literature.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Decani S,
Federighi V,
Baruzzi E,
Sardella A,
Lodi G</span><br />
<span class="medgenPMjournal">J Dermatolog Treat</span>
2014 Dec;25(6):495-500.
Epub 2013 Feb 3
doi: 10.3109/09546634.2012.755252.
<span class="bold">PMID: </span><a href="/pubmed/23210698" target="_blank">23210698</a></div>
<div class="nl"><a target="_blank" href="/pubmed/8835055">Zinc deficiency and taste disorders.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Heyneman CA</span><br />
<span class="medgenPMjournal">Ann Pharmacother</span>
1996 Feb;30(2):186-7.
doi: 10.1177/106002809603000215.
<span class="bold">PMID: </span><a href="/pubmed/8835055" target="_blank">8835055</a></div>
<div class="nl"><a target="_blank" href="/pubmed/4256153">Subclinical pellagra and idiopathic hypogeusia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Green RF</span><br />
<span class="medgenPMjournal">JAMA</span>
1971 Nov 22;218(8):1303.
<span class="bold">PMID: </span><a href="/pubmed/4256153" target="_blank">4256153</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypogeusia%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (102)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/38436682">Outcome predictors of post-COVID conditions in the European Academy of Neurology COVID-19 registry.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Leone MA,
Helbok R,
Bianchi E,
Yasuda CL,
Konti M,
Ramankulov D,
Lolich M,
Lovrencic-Huzjan A,
Kovács T,
Armon C,
Cotelli MS,
Cavallieri F,
Grosu O,
Kiteva-Trenchevska G,
Rodriguez-Leyva I,
Boldingh M,
Brola W,
Maia LF,
de Seabra MML,
Davidescu EI,
Popescu BO,
Kopishinskaia S,
Bassetti CLA,
Moro E;
ENERGY Study Group (§)</span><br />
<span class="medgenPMjournal">J Neurol</span>
2024 Jun;271(6):3153-3168.
Epub 2024 Mar 4
doi: 10.1007/s00415-024-12212-8.
<span class="bold">PMID: </span><a href="/pubmed/38436682" target="_blank">38436682</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33559466">Chemosensory Systems in COVID-19: Evolution of Scientific Research.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Veronese S,
Sbarbati A</span><br />
<span class="medgenPMjournal">ACS Chem Neurosci</span>
2021 Mar 3;12(5):813-824.
Epub 2021 Feb 9
doi: 10.1021/acschemneuro.0c00788.
<span class="bold">PMID: </span><a href="/pubmed/33559466" target="_blank">33559466</a><a href="/pmc/articles/PMC7885804" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33534829">Covid-19 in outpatients-Is fever a useful indicator for SARS-CoV-2 infection?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Schneider A,
Kirsten H,
Lordick F,
Lordick F,
Lübbert C,
von Braun A</span><br />
<span class="medgenPMjournal">PLoS One</span>
2021;16(2):e0246312.
Epub 2021 Feb 3
doi: 10.1371/journal.pone.0246312.
<span class="bold">PMID: </span><a href="/pubmed/33534829" target="_blank">33534829</a><a href="/pmc/articles/PMC7857607" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/16146123">Removable dentures and relations between their construction, adaptation and functionality role and influence on dysgeusia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Zwolak A,
Bakalczuk M,
Leszcz P,
Szabelska A,
Sarna-Boś K,
Kleinrok J</span><br />
<span class="medgenPMjournal">Ann Univ Mariae Curie Sklodowska Med</span>
2004;59(2):432-6.
<span class="bold">PMID: </span><a href="/pubmed/16146123" target="_blank">16146123</a></div>
<div class="nl"><a target="_blank" href="/pubmed/8534187">Cronkhite-Canada syndrome: epidemiological study of 110 cases reported in Japan.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Goto A</span><br />
<span class="medgenPMjournal">Nihon Geka Hokan</span>
1995 Jan 1;64(1):3-14.
<span class="bold">PMID: </span><a href="/pubmed/8534187" target="_blank">8534187</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypogeusia%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (47)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/35248186">Efficacy and safety of gefapixant, a P2X(3) receptor antagonist, in refractory chronic cough and unexplained chronic cough (COUGH-1 and COUGH-2): results from two double-blind, randomised, parallel-group, placebo-controlled, phase 3 trials.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">McGarvey LP,
Birring SS,
Morice AH,
Dicpinigaitis PV,
Pavord ID,
Schelfhout J,
Nguyen AM,
Li Q,
Tzontcheva A,
Iskold B,
Green SA,
Rosa C,
Muccino DR,
Smith JA;
COUGH-1 and COUGH-2 Investigators</span><br />
<span class="medgenPMjournal">Lancet</span>
2022 Mar 5;399(10328):909-923.
doi: 10.1016/S0140-6736(21)02348-5.
<span class="bold">PMID: </span><a href="/pubmed/35248186" target="_blank">35248186</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34289037">Emerging neurotropic features of SARS-CoV-2.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Zhan WR,
Huang J,
Zeng PM,
Tian WY,
Luo ZG</span><br />
<span class="medgenPMjournal">J Mol Cell Biol</span>
2021 Dec 30;13(10):705-711.
doi: 10.1093/jmcb/mjab044.
<span class="bold">PMID: </span><a href="/pubmed/34289037" target="_blank">34289037</a><a href="/pmc/articles/PMC8344859" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/20886348">A study about the frequency of taste disorders.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Welge-Lüssen A,
Dörig P,
Wolfensberger M,
Krone F,
Hummel T</span><br />
<span class="medgenPMjournal">J Neurol</span>
2011 Mar;258(3):386-92.
Epub 2010 Oct 1
doi: 10.1007/s00415-010-5763-5.
<span class="bold">PMID: </span><a href="/pubmed/20886348" target="_blank">20886348</a></div>
<div class="nl"><a target="_blank" href="/pubmed/16146123">Removable dentures and relations between their construction, adaptation and functionality role and influence on dysgeusia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Zwolak A,
Bakalczuk M,
Leszcz P,
Szabelska A,
Sarna-Boś K,
Kleinrok J</span><br />
<span class="medgenPMjournal">Ann Univ Mariae Curie Sklodowska Med</span>
2004;59(2):432-6.
<span class="bold">PMID: </span><a href="/pubmed/16146123" target="_blank">16146123</a></div>
<div class="nl"><a target="_blank" href="/pubmed/15768825">Hypogeusia as a complication of uvulopalatopharyngoplasty and use of taste strips as a practical tool for quantifying hypogeusia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kamel UF</span><br />
<span class="medgenPMjournal">Acta Otolaryngol</span>
2004 Dec;124(10):1235-6.
doi: 10.1080/00016480410016892.
<span class="bold">PMID: </span><a href="/pubmed/15768825" target="_blank">15768825</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypogeusia%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (96)</a></div></div>
</div>
<div class="portlet mgSection" id="ID_104">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">
<div class="nl"><a target="_blank" href="/pubmed/32914677">Oral Manifestations in Patients with COVID-19: A Living Systematic Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Amorim Dos Santos J,
Normando AGC,
Carvalho da Silva RL,
Acevedo AC,
De Luca Canto G,
Sugaya N,
Santos-Silva AR,
Guerra ENS</span><br />
<span class="medgenPMjournal">J Dent Res</span>
2021 Feb;100(2):141-154.
Epub 2020 Sep 11
doi: 10.1177/0022034520957289.
<span class="bold">PMID: </span><a href="/pubmed/32914677" target="_blank">32914677</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32609889">A Systematic Review and Meta-Analysis of Taste Dysfunction in Chronic Rhinosinusitis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Xie DX,
Leland EM,
Seal SM,
Lin SY,
Rowan NR</span><br />
<span class="medgenPMjournal">Laryngoscope</span>
2021 Mar;131(3):482-489.
Epub 2020 Jul 1
doi: 10.1002/lary.28827.
<span class="bold">PMID: </span><a href="/pubmed/32609889" target="_blank">32609889</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32660520">Neurological manifestations of COVID-19: a systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Nepal G,
Rehrig JH,
Shrestha GS,
Shing YK,
Yadav JK,
Ojha R,
Pokhrel G,
Tu ZL,
Huang DY</span><br />
<span class="medgenPMjournal">Crit Care</span>
2020 Jul 13;24(1):421.
doi: 10.1186/s13054-020-03121-z.
<span class="bold">PMID: </span><a href="/pubmed/32660520" target="_blank">32660520</a><a href="/pmc/articles/PMC7356133" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29260510">Interventions for managing taste disturbances.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kumbargere Nagraj S,
George RP,
Shetty N,
Levenson D,
Ferraiolo DM,
Shrestha A</span><br />
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
2017 Dec 20;12(12):CD010470.
doi: 10.1002/14651858.CD010470.pub3.
<span class="bold">PMID: </span><a href="/pubmed/29260510" target="_blank">29260510</a><a href="/pmc/articles/PMC6486004" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25425011">Interventions for the management of taste disturbances.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Nagraj SK,
Naresh S,
Srinivas K,
Renjith George P,
Shrestha A,
Levenson D,
Ferraiolo DM</span><br />
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
2014 Nov 26;(11):CD010470.
doi: 10.1002/14651858.CD010470.pub2.
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Hypogeusia%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (9)</a></div></div>
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