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<meta name="keywords" content="C0149696, disease or syndrome, finding, food intolerance, food, sensitivity, intolerance to food, intolerance, food, non-allergic food hypersensitivity, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A detrimental reaction to a food, beverage, food additive, or compound found in foods that produces symptoms in one or more body organs and systems that is not mediated by an immune reaction." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
UID=57440
ConceptID=C0149696
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Food intolerance</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>57440</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0149696</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome; Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
<td>Food Intolerance; Food, Sensitivity; Intolerance, Food</td></tr>
<tr><td><span class="bold">SNOMED CT: </span></td>
<td>Food intolerance (235719002); Intolerance to food (235719002)</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0012537">HP:0012537</a></td></tr>
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">A detrimental reaction to a food, beverage, food additive, or compound found in foods that produces symptoms in one or more body organs and systems that is not mediated by an immune reaction. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
</div>
<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Food intolerance</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/867398" ref="tree=MeSH" title="MedGen record for Abnormality of metabolism/homeostasis">Abnormality of metabolism/homeostasis</a></span><ul><li><span class="TLline"><a href="/medgen/868551" ref="tree=MeSH" title="MedGen record for Abnormal homeostasis">Abnormal homeostasis</a></span><ul><li><span class="matched_ds">Food intolerance</span><ul><li><span class="TLline"><a href="/medgen/234665" ref="tree=MeSH" title="MedGen record for Intolerance to protein">Intolerance to protein</a></span><ul><li><span class="TLline"><a href="/medgen/1370572" ref="tree=MeSH" title="MedGen record for Gluten intolerance">Gluten intolerance</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_112">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln clinfeat">
<div class="divPopper rprt" id="rdis_59799"><div><strong>Williams syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>59799</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0175702</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Williams syndrome (WS) is characterized by developmental delay, intellectual disability (usually mild), a specific cognitive profile, unique personality characteristics, cardiovascular disease (supravalvar aortic stenosis, peripheral pulmonary stenosis, hypertension), connective tissue abnormalities, growth deficiency, endocrine abnormalities (early puberty, hypercalcemia, hypercalciuria, hypothyroidism), and distinctive facies. Hypotonia and hyperextensible joints can result in delayed attainment of motor milestones. Feeding difficulties often lead to poor weight gain in infancy.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/59799">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_322026"><div><strong>ALG3-congenital disorder of glycosylation</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>322026</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1832736</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Congenital disorders of glycosylation (CDGs) are a genetically heterogeneous group of autosomal recessive disorders caused by enzymatic defects in the synthesis and processing of asparagine (N)-linked glycans or oligosaccharides on glycoproteins. Type I CDGs comprise defects in the assembly of the dolichol lipid-linked oligosaccharide (LLO) chain and its transfer to the nascent protein. These disorders can be identified by a characteristic abnormal isoelectric focusing profile of plasma transferrin (Leroy, 2006).&#13; CDG1D is a type I CDG that generally presents with severe neurologic involvement associated with dysmorphism and visual impairment. Liver involvement is sometimes present (summary by Marques-da-Silva et al., 2017).&#13; For a discussion of the classification of CDGs, see CDG1A (212065).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/322026">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_350353"><div><strong>Dermatitis, atopic</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>350353</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1864155</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove nowrap">See: <a href="/medgen/350353">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1785846"><div><strong>Osteootohepatoenteric syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1785846</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C5543557</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Osteootohepatoenteric syndrome (OOHE) is characterized by a variable combination of bone fragility, hearing loss, cholestasis, and congenital diarrhea. Some patients also display mild developmental delay and intellectual disability (Esteve et al., 2018).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1785846">Condition Record</a></div></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_322026" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">ALG3-congenital disorder of glycosylation</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_350353" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Dermatitis, atopic</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1785846" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Osteootohepatoenteric syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_59799" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Williams syndrome</a></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/38326194">Current and future perspectives on the consensus guideline for food protein-induced enterocolitis syndrome (FPIES).</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Anvari S,
Ruffner MA,
Nowak-Wegrzyn A</span><br />
<span class="medgenPMjournal">Allergol Int</span>
2024 Apr;73(2):188-195.
Epub 2024 Feb 7
doi: 10.1016/j.alit.2024.01.006.
<span class="bold">PMID: </span><a href="/pubmed/38326194" target="_blank">38326194</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25316115">Review article: the diagnosis and management of food allergy and food intolerances.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Turnbull JL,
Adams HN,
Gorard DA</span><br />
<span class="medgenPMjournal">Aliment Pharmacol Ther</span>
2015 Jan;41(1):3-25.
Epub 2014 Oct 14
doi: 10.1111/apt.12984.
<span class="bold">PMID: </span><a href="/pubmed/25316115" target="_blank">25316115</a></div>
<div class="nl"><a target="_blank" href="/pubmed/21134576">Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">NIAID-Sponsored Expert Panel,
Boyce JA,
Assa'ad A,
Burks AW,
Jones SM,
Sampson HA,
Wood RA,
Plaut M,
Cooper SF,
Fenton MJ,
Arshad SH,
Bahna SL,
Beck LA,
Byrd-Bredbenner C,
Camargo CA Jr,
Eichenfield L,
Furuta GT,
Hanifin JM,
Jones C,
Kraft M,
Levy BD,
Lieberman P,
Luccioli S,
McCall KM,
Schneider LC,
Simon RA,
Simons FE,
Teach SJ,
Yawn BP,
Schwaninger JM</span><br />
<span class="medgenPMjournal">J Allergy Clin Immunol</span>
2010 Dec;126(6 Suppl):S1-58.
doi: 10.1016/j.jaci.2010.10.007.
<span class="bold">PMID: </span><a href="/pubmed/21134576" target="_blank">21134576</a><a href="/pmc/articles/PMC4241964" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22food%20intolerance%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (50)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/34068047">Food Allergy and Intolerance: A Narrative Review on Nutritional Concerns.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gargano D,
Appanna R,
Santonicola A,
De Bartolomeis F,
Stellato C,
Cianferoni A,
Casolaro V,
Iovino P</span><br />
<span class="medgenPMjournal">Nutrients</span>
2021 May 13;13(5)
doi: 10.3390/nu13051638.
<span class="bold">PMID: </span><a href="/pubmed/34068047" target="_blank">34068047</a><a href="/pmc/articles/PMC8152468" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33233102">Relationships between food and diseases: What to know to ensure food safety.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gallo M,
Ferrara L,
Calogero A,
Montesano D,
Naviglio D</span><br />
<span class="medgenPMjournal">Food Res Int</span>
2020 Nov;137:109414.
Epub 2020 Jun 9
doi: 10.1016/j.foodres.2020.109414.
<span class="bold">PMID: </span><a href="/pubmed/33233102" target="_blank">33233102</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31930423">Food Allergy: A Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Seth D,
Poowutikul P,
Pansare M,
Kamat D</span><br />
<span class="medgenPMjournal">Pediatr Ann</span>
2020 Jan 1;49(1):e50-e58.
doi: 10.3928/19382359-20191206-01.
<span class="bold">PMID: </span><a href="/pubmed/31930423" target="_blank">31930423</a></div>
<div class="nl"><a target="_blank" href="/pubmed/26400113">Down syndrome--genetic and nutritional aspects of accompanying disorders.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Mazurek D,
Wyka J</span><br />
<span class="medgenPMjournal">Rocz Panstw Zakl Hig</span>
2015;66(3):189-94.
<span class="bold">PMID: </span><a href="/pubmed/26400113" target="_blank">26400113</a></div>
<div class="nl"><a target="_blank" href="/pubmed/3279094">IgE-mediated food intolerance.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sampson HA</span><br />
<span class="medgenPMjournal">J Allergy Clin Immunol</span>
1988 Mar;81(3):495-504.
<span class="bold">PMID: </span><a href="/pubmed/3279094" target="_blank">3279094</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Food%20intolerance%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (409)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/38674909">Histamine Intolerance: Symptoms, Diagnosis, and Beyond.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Jochum C</span><br />
<span class="medgenPMjournal">Nutrients</span>
2024 Apr 19;16(8)
doi: 10.3390/nu16081219.
<span class="bold">PMID: </span><a href="/pubmed/38674909" target="_blank">38674909</a><a href="/pmc/articles/PMC11054089" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/38068827">Myths and Facts about Food Intolerance: A Narrative Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Zingone F,
Bertin L,
Maniero D,
Palo M,
Lorenzon G,
Barberio B,
Ciacci C,
Savarino EV</span><br />
<span class="medgenPMjournal">Nutrients</span>
2023 Nov 30;15(23)
doi: 10.3390/nu15234969.
<span class="bold">PMID: </span><a href="/pubmed/38068827" target="_blank">38068827</a><a href="/pmc/articles/PMC10708184" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32824107">Histamine Intolerance: The Current State of the Art.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Comas-Basté O,
Sánchez-Pérez S,
Veciana-Nogués MT,
Latorre-Moratalla M,
Vidal-Carou MDC</span><br />
<span class="medgenPMjournal">Biomolecules</span>
2020 Aug 14;10(8)
doi: 10.3390/biom10081181.
<span class="bold">PMID: </span><a href="/pubmed/32824107" target="_blank">32824107</a><a href="/pmc/articles/PMC7463562" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31930423">Food Allergy: A Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Seth D,
Poowutikul P,
Pansare M,
Kamat D</span><br />
<span class="medgenPMjournal">Pediatr Ann</span>
2020 Jan 1;49(1):e50-e58.
doi: 10.3928/19382359-20191206-01.
<span class="bold">PMID: </span><a href="/pubmed/31930423" target="_blank">31930423</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30783042">Lactose Intolerance: Common Misunderstandings.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Di Costanzo M,
Berni Canani R</span><br />
<span class="medgenPMjournal">Ann Nutr Metab</span>
2018;73 Suppl 4:30-37.
Epub 2019 Feb 19
doi: 10.1159/000493669.
<span class="bold">PMID: </span><a href="/pubmed/30783042" target="_blank">30783042</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Food%20intolerance%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (440)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/34209583">Histamine Intolerance-The More We Know the Less We Know. A Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Hrubisko M,
Danis R,
Huorka M,
Wawruch M</span><br />
<span class="medgenPMjournal">Nutrients</span>
2021 Jun 29;13(7)
doi: 10.3390/nu13072228.
<span class="bold">PMID: </span><a href="/pubmed/34209583" target="_blank">34209583</a><a href="/pmc/articles/PMC8308327" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34068047">Food Allergy and Intolerance: A Narrative Review on Nutritional Concerns.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gargano D,
Appanna R,
Santonicola A,
De Bartolomeis F,
Stellato C,
Cianferoni A,
Casolaro V,
Iovino P</span><br />
<span class="medgenPMjournal">Nutrients</span>
2021 May 13;13(5)
doi: 10.3390/nu13051638.
<span class="bold">PMID: </span><a href="/pubmed/34068047" target="_blank">34068047</a><a href="/pmc/articles/PMC8152468" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33921522">Histamine Intolerance Originates in the Gut.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Schnedl WJ,
Enko D</span><br />
<span class="medgenPMjournal">Nutrients</span>
2021 Apr 12;13(4)
doi: 10.3390/nu13041262.
<span class="bold">PMID: </span><a href="/pubmed/33921522" target="_blank">33921522</a><a href="/pmc/articles/PMC8069563" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31930423">Food Allergy: A Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Seth D,
Poowutikul P,
Pansare M,
Kamat D</span><br />
<span class="medgenPMjournal">Pediatr Ann</span>
2020 Jan 1;49(1):e50-e58.
doi: 10.3928/19382359-20191206-01.
<span class="bold">PMID: </span><a href="/pubmed/31930423" target="_blank">31930423</a></div>
<div class="nl"><a target="_blank" href="/pubmed/3885225">Food intolerance.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Lessof MH</span><br />
<span class="medgenPMjournal">Proc Nutr Soc</span>
1985 Feb;44(1):121-5.
doi: 10.1079/pns19850020.
<span class="bold">PMID: </span><a href="/pubmed/3885225" target="_blank">3885225</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Food%20intolerance%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (402)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/34579083">Food Intolerance: The Role of Histamine.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Shulpekova YO,
Nechaev VM,
Popova IR,
Deeva TA,
Kopylov AT,
Malsagova KA,
Kaysheva AL,
Ivashkin VT</span><br />
<span class="medgenPMjournal">Nutrients</span>
2021 Sep 15;13(9)
doi: 10.3390/nu13093207.
<span class="bold">PMID: </span><a href="/pubmed/34579083" target="_blank">34579083</a><a href="/pmc/articles/PMC8469513" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31336652">Food Intolerances.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tuck CJ,
Biesiekierski JR,
Schmid-Grendelmeier P,
Pohl D</span><br />
<span class="medgenPMjournal">Nutrients</span>
2019 Jul 22;11(7)
doi: 10.3390/nu11071684.
<span class="bold">PMID: </span><a href="/pubmed/31336652" target="_blank">31336652</a><a href="/pmc/articles/PMC6682924" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/15984592">Food intolerance, flushing, and diarrhea in a 44-year-old woman.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Poole JA,
Nanda A,
Matangkasombut P,
Katial RK</span><br />
<span class="medgenPMjournal">Ann Allergy Asthma Immunol</span>
2005 Jun;94(6):621-6.
doi: 10.1016/S1081-1206(10)61318-X.
<span class="bold">PMID: </span><a href="/pubmed/15984592" target="_blank">15984592</a></div>
<div class="nl"><a target="_blank" href="/pubmed/9656325">The role of nutrition and diet in rheumatoid arthritis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Martin RH</span><br />
<span class="medgenPMjournal">Proc Nutr Soc</span>
1998 May;57(2):231-4.
doi: 10.1079/pns19980036.
<span class="bold">PMID: </span><a href="/pubmed/9656325" target="_blank">9656325</a></div>
<div class="nl"><a target="_blank" href="/pubmed/3279094">IgE-mediated food intolerance.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sampson HA</span><br />
<span class="medgenPMjournal">J Allergy Clin Immunol</span>
1988 Mar;81(3):495-504.
<span class="bold">PMID: </span><a href="/pubmed/3279094" target="_blank">3279094</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Food%20intolerance%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (150)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/37242236">New Insights and Evidence on "Food Intolerances": Non-Celiac Gluten Sensitivity and Nickel Allergic Contact Mucositis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Greco N,
Pisano A,
Mezzatesta L,
Pettinelli M,
Meacci A,
Pignataro MG,
Giordano C,
Picarelli A</span><br />
<span class="medgenPMjournal">Nutrients</span>
2023 May 17;15(10)
doi: 10.3390/nu15102353.
<span class="bold">PMID: </span><a href="/pubmed/37242236" target="_blank">37242236</a><a href="/pmc/articles/PMC10222428" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36614252">Molecular Mechanisms of Scombroid Food Poisoning.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Zhernov YV,
Simanduyev MY,
Zaostrovtseva OK,
Semeniako EE,
Kolykhalova KI,
Fadeeva IA,
Kashutina MI,
Vysochanskaya SO,
Belova EV,
Shcherbakov DV,
Sukhov VA,
Sidorova EA,
Mitrokhin OV</span><br />
<span class="medgenPMjournal">Int J Mol Sci</span>
2023 Jan 3;24(1)
doi: 10.3390/ijms24010809.
<span class="bold">PMID: </span><a href="/pubmed/36614252" target="_blank">36614252</a><a href="/pmc/articles/PMC9821622" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36501141">Long-Term Effects of an Oligoantigenic Diet in Children with Attention-Deficit/Hyperactivity Disorder (ADHD) on Core Symptomatology.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Walz G,
Blazynski N,
Frey L,
Schneider-Momm K,
Clement HW,
Rauh R,
Schulz E,
Biscaldi M,
Clement C,
Fleischhaker C</span><br />
<span class="medgenPMjournal">Nutrients</span>
2022 Dec 1;14(23)
doi: 10.3390/nu14235111.
<span class="bold">PMID: </span><a href="/pubmed/36501141" target="_blank">36501141</a><a href="/pmc/articles/PMC9737158" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31336652">Food Intolerances.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tuck CJ,
Biesiekierski JR,
Schmid-Grendelmeier P,
Pohl D</span><br />
<span class="medgenPMjournal">Nutrients</span>
2019 Jul 22;11(7)
doi: 10.3390/nu11071684.
<span class="bold">PMID: </span><a href="/pubmed/31336652" target="_blank">31336652</a><a href="/pmc/articles/PMC6682924" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/24076059">A diet low in FODMAPs reduces symptoms of irritable bowel syndrome.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Halmos EP,
Power VA,
Shepherd SJ,
Gibson PR,
Muir JG</span><br />
<span class="medgenPMjournal">Gastroenterology</span>
2014 Jan;146(1):67-75.e5.
Epub 2013 Sep 25
doi: 10.1053/j.gastro.2013.09.046.
<span class="bold">PMID: </span><a href="/pubmed/24076059" target="_blank">24076059</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Food%20intolerance%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (184)</a></div></div>
</div>
<div class="portlet mgSection" id="ID_104">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">
<div class="nl"><a target="_blank" href="/pubmed/35631198">Exclusion Diets in Functional Dyspepsia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Popa SL,
Dumitrascu DI,
Pop C,
Surdea-Blaga T,
Ismaiel A,
Chiarioni G,
Dumitrascu DL,
Brata VD,
Grad S</span><br />
<span class="medgenPMjournal">Nutrients</span>
2022 May 14;14(10)
doi: 10.3390/nu14102057.
<span class="bold">PMID: </span><a href="/pubmed/35631198" target="_blank">35631198</a><a href="/pmc/articles/PMC9144481" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33383523">A systematic review of psychological, clinical and psychosocial correlates of perceived food intolerance.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">De Petrillo A,
Hughes LD,
McGuinness S,
Roberts D,
Godfrey E</span><br />
<span class="medgenPMjournal">J Psychosom Res</span>
2021 Feb;141:110344.
Epub 2020 Dec 18
doi: 10.1016/j.jpsychores.2020.110344.
<span class="bold">PMID: </span><a href="/pubmed/33383523" target="_blank">33383523</a></div>
<div class="nl"><a target="_blank" href="/pubmed/26633487">Gliadin-Specific T-Cells Mobilized in the Peripheral Blood of Coeliac Patients by Short Oral Gluten Challenge: Clinical Applications.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Picascia S,
Mandile R,
Auricchio R,
Troncone R,
Gianfrani C</span><br />
<span class="medgenPMjournal">Nutrients</span>
2015 Dec 2;7(12):10020-31.
doi: 10.3390/nu7125515.
<span class="bold">PMID: </span><a href="/pubmed/26633487" target="_blank">26633487</a><a href="/pmc/articles/PMC4690067" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/24968745">Primary banded Roux-en-Y gastric bypass: a systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Mahawar KK,
Parikh C,
Carr WR,
Jennings N,
Balupuri S,
Small PK</span><br />
<span class="medgenPMjournal">Obes Surg</span>
2014 Oct;24(10):1771-92.
doi: 10.1007/s11695-014-1346-3.
<span class="bold">PMID: </span><a href="/pubmed/24968745" target="_blank">24968745</a></div>
<div class="nl"><a target="_blank" href="/pubmed/24857310">Endometriosis and type 1 allergies/immediate type hypersensitivity: a systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Bungum HF,
Vestergaard C,
Knudsen UB</span><br />
<span class="medgenPMjournal">Eur J Obstet Gynecol Reprod Biol</span>
2014 Aug;179:209-15.
Epub 2014 Apr 26
doi: 10.1016/j.ejogrb.2014.04.025.
<span class="bold">PMID: </span><a href="/pubmed/24857310" target="_blank">24857310</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Food%20intolerance%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (23)</a></div></div>
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