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<!--
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UID=56353
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ConceptID=C0155119
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Recurrent corneal erosions</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>56353</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0155119</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Recurrent corneal ulceration; Recurrent corneal ulcerations</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Recurrent erosion syndrome (2055003); Recurrent corneal erosion (2055003); Recurrent erosion of cornea (2055003)</td></tr>
|
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<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0000495">HP:0000495</a></td></tr>
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||
<div class="portlet_content ln">The presence of recurrent corneal epithelial erosions. Although most corneal epithelial defects heal quickly, some may show recurrent ulcerations. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Recurrent corneal erosions</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/1370071" ref="tree=MeSH" title="MedGen record for Abnormality of the eye">Abnormality of the eye</a></span><ul><li><span class="TLline"><a href="/medgen/868526" ref="tree=MeSH" title="MedGen record for Abnormal eye morphology">Abnormal eye morphology</a></span><ul><li><span class="TLline"><a href="/medgen/870894" ref="tree=MeSH" title="MedGen record for Abnormal anterior eye segment morphology">Abnormal anterior eye segment morphology</a></span><ul><li><span class="TLline"><a href="/medgen/383737" ref="tree=MeSH" title="MedGen record for Abnormal cornea morphology">Abnormal cornea morphology</a></span><ul><li><span class="TLline"><a href="/medgen/868915" ref="tree=MeSH" title="MedGen record for Abnormal corneal epithelium morphology">Abnormal corneal epithelium morphology</a></span><ul><li><span class="TLline"><a href="/medgen/97882" ref="tree=MeSH" title="MedGen record for Corneal erosion">Corneal erosion</a></span><ul><li><span class="matched_ds">Recurrent corneal erosions</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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<div class="portlet mgSection" id="ID_112">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln clinfeat">
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<div class="divPopper rprt" id="rdis_41678"><div><strong>Familial dysautonomia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>41678</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0013364</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Familial dysautonomia, which affects the development and survival of sensory, sympathetic, and parasympathetic neurons, is a debilitating disorder present from birth. Neuronal degeneration progresses throughout life. Affected individuals have gastrointestinal dysfunction, autonomic crises (i.e., hypertensive vomiting attacks), recurrent pneumonia, altered pain sensitivity, altered temperature perception, and blood pressure instability. Hypotonia contributes to delay in acquisition of motor milestones. Optic neuropathy results in progressive vision loss. Older individuals often have a broad-based and ataxic gait that deteriorates over time. Developmental delay / intellectual disability occur in about 21% of individuals. Life expectancy is decreased.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/41678">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_6915"><div><strong>Hereditary insensitivity to pain with anhidrosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>6915</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0020074</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">NTRK1 congenital insensitivity to pain with anhidrosis (NTRK1-CIPA) is characterized by insensitivity to pain, anhidrosis (the inability to sweat), and intellectual disability. The ability to sense all pain (including visceral pain) is absent, resulting in repeated injuries including: oral self-mutilation (biting of tongue, lips, and buccal mucosa); biting of fingertips; bruising, scarring, and infection of the skin; multiple bone fractures (many of which fail to heal properly); and recurrent joint dislocations resulting in joint deformity. Sense of touch, vibration, and position are normal. Anhidrosis predisposes to recurrent febrile episodes that are often the initial manifestation of NTRK1-CIPA. Hypothermia in cold environments also occurs. Intellectual disability of varying degree is observed in most affected individuals; hyperactivity and emotional lability are common.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/6915">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_120536"><div><strong>Autosomal dominant keratitis-ichthyosis-hearing loss syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>120536</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0265336</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Keratitis-ichthyosis-deafness (KID) syndrome is a rare ectodermal dysplasia characterized by sensorineural hearing loss, photophobia and corneal vascularization, hyperkeratosis of the palms and soles, erythrokeratoderma, follicular hyperkeratosis, and recurrent bacterial and fungal infections. A subset of patients with KID may develop multiple cystic pilar tumors, which are prone to malignant transformation and metastasis (Nyquist et al., 2007). Vohwinkel syndrome (124500) is an allelic disorder involving congenital deafness with keratopachydermia and constrictions of fingers and toes. Another similar disorder caused by mutation in GJB2 is palmoplantar keratoderma with deafness (148350). Genetic Heterogeneity of Keratitis-Ichthyosis-Deafness Syndrome An autosomal recessive form of KID syndrome (KIDAR; 242150) is caused by mutation in the AP1B1 gene (600157) on chromosome 22q12.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/120536">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_75566"><div><strong>Distichiasis-lymphedema syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>75566</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0265345</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Lymphedema-distichiasis syndrome (referred to as LDS in this GeneReview) is characterized by lower-limb lymphedema, and distichiasis (aberrant eyelashes ranging from a full set of extra eyelashes to a single hair). Lymphedema typically appears in late childhood or puberty, is confined to the lower limbs with or without involvement of the external genitalia, and is often asymmetric; severity varies within families. Males develop edema at an earlier age and have more problems with cellulitis than females. Distichiasis, which may be present at birth, is observed in 94% of affected individuals. About 75% of affected individuals have ocular findings including corneal irritation, recurrent conjunctivitis, and photophobia; other common findings include varicose veins and ptosis.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/75566">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_98141"><div><strong>Cloverleaf skull syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>98141</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0432126</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Cloverleaf skull, or Kleeblattschaedel, consists of a trilobular skull with craniosynostosis. The condition shows pathogenetic variability and etiologic heterogeneity. The cause of isolated cloverleaf skull is unknown (Cohen, 2009). Cohen (1975) pointed out that Kleeblattschaedel is a component of many syndromes, e.g., it is found in some cases of Crouzon syndrome (123500), Pfeiffer syndrome (101600), and Carpenter syndrome (201000). Cohen (2009) listed 12 monogenic disorders with cloverleaf skull as a feature, including type II thanatophoric dysplasia (187601), which accounts for 40% of all cloverleaf skull syndromes. Cohen (2009) published photographs of cloverleaf skull in various syndromes.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/98141">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_99275"><div><strong>Epithelial basement membrane dystrophy</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>99275</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0521723</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Epithelial basement membrane corneal dystrophy (EBMD) is a common bilateral epithelial dystrophy characterized mainly by sheet-like areas of basement membrane originating from the basal epithelial cells of the corneal epithelium and extending superficially into the epithelium. Slit lamp examination may reveal dots, maps, grayish epithelial fingerprint lines, blebs, nets, or any combination of these patterns. Histologic analysis shows abnormal redundant basement membrane and intraepithelial lacunae filled with cellular debris. Most patients are asymptomatic before the age of 30 years; some may have recurrent erosions, the frequency of which declines with age, and a loss of vision due to surface irregularity (summary by Boutboul et al., 2006).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/99275">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_351514"><div><strong>Macular corneal dystrophy</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>351514</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1636149</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Macular corneal dystrophy (MCD) is an autosomal recessive disorder in which progressive punctate opacities in the cornea result in bilateral loss of vision, eventually necessitating corneal transplantation. MCD is classified into 2 subtypes, type I and type II, defined by the respective absence and presence of sulfated keratan sulfate in the patient serum, although both types have clinically indistinguishable phenotypes (summary by Akama et al., 2000).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/351514">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_305533"><div><strong>Lattice corneal dystrophy Type I</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>305533</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1690006</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Lattice corneal dystrophy type I (CDL1) is an autosomal dominant condition characterized by deposition of amyloid in the corneal stroma. Onset occurs in the first or second decade of life and progresses over time. The anterior stroma has rod-like or linear opacities. Recurrent erosions are common and central anterior stromal haze may develop with age. The lesions usually affect the anterior and central corneas, leaving a relatively normal periphery (summary by Lin et al., 2016).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/305533">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_338045"><div><strong>Mitochondrial DNA depletion syndrome 6 (hepatocerebral type)</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>338045</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1850406</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">MPV17-related mitochondrial DNA (mtDNA) maintenance defect presents in the vast majority of affected individuals as an early-onset encephalohepatopathic (hepatocerebral) disease that is typically associated with mtDNA depletion, particularly in the liver. A later-onset neuromyopathic disease characterized by myopathy and neuropathy, and associated with multiple mtDNA deletions in muscle, has also rarely been described. MPV17-related mtDNA maintenance defect, encephalohepatopathic form is characterized by: Hepatic manifestations (liver dysfunction that typically progresses to liver failure, cholestasis, hepatomegaly, and steatosis); Neurologic involvement (developmental delay, hypotonia, microcephaly, and motor and sensory peripheral neuropathy); Gastrointestinal manifestations (gastrointestinal dysmotility, feeding difficulties, and failure to thrive); and Metabolic derangements (lactic acidosis and hypoglycemia). Less frequent manifestations include renal tubulopathy, nephrocalcinosis, and hypoparathyroidism. Progressive liver disease often leads to death in infancy or early childhood. Hepatocellular carcinoma has been reported.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/338045">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_419735"><div><strong>Nephropathic cystinosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>419735</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2931187</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Cystinosis comprises three allelic phenotypes: Nephropathic cystinosis in untreated children is characterized by renal Fanconi syndrome, poor growth, hypophosphatemic/calcipenic rickets, impaired glomerular function resulting in complete glomerular failure, and accumulation of cystine in almost all cells, leading to cellular dysfunction with tissue and organ impairment. The typical untreated child has short stature, rickets, and photophobia. Failure to thrive is generally noticed after approximately age six months; signs of renal tubular Fanconi syndrome (polyuria, polydipsia, dehydration, and acidosis) appear as early as age six months; corneal crystals can be present before age one year and are always present after age 16 months. Prior to the use of renal transplantation and cystine-depleting therapy, the life span in nephropathic cystinosis was no longer than ten years. With these interventions, affected individuals can survive at least into the mid-forties or fifties with satisfactory quality of life. Intermediate cystinosis is characterized by all the typical manifestations of nephropathic cystinosis, but onset is at a later age. Renal glomerular failure occurs in all untreated affected individuals, usually between ages 15 and 25 years. The non-nephropathic (ocular) form of cystinosis is characterized clinically only by photophobia resulting from corneal cystine crystal accumulation.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/419735">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1684798"><div><strong>Corneal dystrophy, Meesmann, 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1684798</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5231495</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Meesmann corneal dystrophy-2 (MECD2) is characterized by fragility of the anterior corneal epithelium and the presence of intraepithelial microcysts. Although the disease is generally mild and affected individuals are often asymptomatic, some suffer from recurrent erosions leading to lacrimation, photophobia, and deterioration in visual acuity (summary by Szaflik et al., 2008). For a discussion of genetic heterogeneity of Meesmann corneal dystrophy, see MECD1 (122100).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1684798">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1746744"><div><strong>IFAP syndrome 1, with or without BRESHECK syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1746744</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5399971</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The IFAP/BRESHECK syndrome is an X-linked multiple congenital anomaly disorder with variable severity. The classic triad, which defines IFAP, is ichthyosis follicularis, atrichia, and photophobia. Some patients have additional features, including mental retardation, brain anomalies, Hirschsprung disease, corneal opacifications, kidney dysplasia, cryptorchidism, cleft palate, and skeletal malformations, particularly of the vertebrae, which constitutes BRESHECK syndrome (summary by Naiki et al., 2012). Genetic Heterogeneity of IFAP Syndrome IFAP syndrome-2 (IFAP2; 619016) is caused by heterozygous mutation in the SREBF1 gene (184756) on chromosome 17p11.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1746744">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1824096"><div><strong>LADD syndrome 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1824096</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5774323</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Lacrimoauriculodentodigital syndrome-1 (LADD1) is a multiple congenital anomaly disorder mainly affecting lacrimal glands and ducts, salivary glands and ducts, ears, teeth, and distal limb segments (summary by Rohmann et al., 2006). Genetic Heterogeneity of Lacrimoauriculodentodigital Syndrome LADD syndrome-2 (LADD2; 620192) is caused by mutation in the FGFR3 gene (134934) on chromosome 4p16, and LADD syndrome-3 (LADD3; 620193) is caused by mutation in the FGF10 gene, an FGFR ligand, on chromosome 5p12.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1824096">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_120536" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Autosomal dominant keratitis-ichthyosis-hearing loss syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_98141" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cloverleaf skull syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1684798" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Corneal dystrophy, Meesmann, 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_75566" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Distichiasis-lymphedema syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_99275" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Epithelial basement membrane dystrophy</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (13)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_41678" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial dysautonomia</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_6915" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hereditary insensitivity to pain with anhidrosis</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1746744" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">IFAP syndrome 1, with or without BRESHECK syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1824096" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">LADD syndrome 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_305533" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Lattice corneal dystrophy Type I</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_351514" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Macular corneal dystrophy</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_338045" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Mitochondrial DNA depletion syndrome 6 (hepatocerebral type)</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_419735" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Nephropathic cystinosis</a></div></span></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/29895082">Recurrent Corneal Erosions in Corneal Dystrophies: a Review of the Pathogenesis, Differential Diagnosis, and Therapy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Omari AA,
|
||
Mian SI</span><br />
|
||
<span class="medgenPMjournal">Klin Monbl Augenheilkd</span>
|
||
2018 Jun;235(6):689-696.
|
||
Epub 2018 Jun 12
|
||
doi: 10.1055/a-0592-7925.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29895082" target="_blank">29895082</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24421300">Management of recurrent corneal erosions: are we getting better?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mencucci R,
|
||
Favuzza E</span><br />
|
||
<span class="medgenPMjournal">Br J Ophthalmol</span>
|
||
2014 Feb;98(2):150-1.
|
||
doi: 10.1136/bjophthalmol-2013-303749.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24421300" target="_blank">24421300</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17571089">Reply to ramamurthi and rahman: induction of ptosis with botulinum toxin for thr treatment of recurrent corneal erosions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bailey CS</span><br />
|
||
<span class="medgenPMjournal">Eye (Lond)</span>
|
||
2007 Aug;21(8):1128.
|
||
Epub 2007 Jun 15
|
||
doi: 10.1038/sj.eye.6702899.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17571089" target="_blank">17571089</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22recurrent%20corneal%20erosions%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (22)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37490883">Safety and Efficacy of the Phototherapeutic Keratectomy for Treatment of Recurrent Corneal Erosions: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chen S,
|
||
Chu X,
|
||
Zhang C,
|
||
Jia Z,
|
||
Yang L,
|
||
Yang R,
|
||
Huang Y,
|
||
Zhao S</span><br />
|
||
<span class="medgenPMjournal">Ophthalmic Res</span>
|
||
2023;66(1):1114-1127.
|
||
Epub 2023 Jul 25
|
||
doi: 10.1159/000533160.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37490883" target="_blank">37490883</a><a href="/pmc/articles/PMC10614516" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35326011">Transepithelial phototherapeutic keratectomy for post-traumatic recurrent corneal erosions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang R,
|
||
Wang Q,
|
||
Li J,
|
||
Sun L,
|
||
Jhanji V,
|
||
Jiang J,
|
||
Zhang M</span><br />
|
||
<span class="medgenPMjournal">Indian J Ophthalmol</span>
|
||
2022 Apr;70(4):1186-1189.
|
||
doi: 10.4103/ijo.IJO_2340_21.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35326011" target="_blank">35326011</a><a href="/pmc/articles/PMC9240583" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30736080">Contact Lenses in the Management of Corneal Dystrophies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Farooq AV,
|
||
Colby K</span><br />
|
||
<span class="medgenPMjournal">Klin Monbl Augenheilkd</span>
|
||
2020 Feb;237(2):175-179.
|
||
Epub 2019 Feb 8
|
||
doi: 10.1055/a-0735-9801.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30736080" target="_blank">30736080</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29985545">Interventions for recurrent corneal erosions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Watson SL,
|
||
Leung V</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2018 Jul 9;7(7):CD001861.
|
||
doi: 10.1002/14651858.CD001861.pub4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29985545" target="_blank">29985545</a><a href="/pmc/articles/PMC6513638" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22972054">Interventions for recurrent corneal erosions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Watson SL,
|
||
Lee MH,
|
||
Barker NH</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2012 Sep 12;(9):CD001861.
|
||
doi: 10.1002/14651858.CD001861.pub3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22972054" target="_blank">22972054</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Recurrent%20corneal%20erosions%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (62)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/31306672">Phototherapeutic keratectomy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nagpal R,
|
||
Maharana PK,
|
||
Roop P,
|
||
Murthy SI,
|
||
Rapuano CJ,
|
||
Titiyal JS,
|
||
Vajpayee RB,
|
||
Sharma N</span><br />
|
||
<span class="medgenPMjournal">Surv Ophthalmol</span>
|
||
2020 Jan-Feb;65(1):79-108.
|
||
Epub 2019 Jul 12
|
||
doi: 10.1016/j.survophthal.2019.07.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31306672" target="_blank">31306672</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29895082">Recurrent Corneal Erosions in Corneal Dystrophies: a Review of the Pathogenesis, Differential Diagnosis, and Therapy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Omari AA,
|
||
Mian SI</span><br />
|
||
<span class="medgenPMjournal">Klin Monbl Augenheilkd</span>
|
||
2018 Jun;235(6):689-696.
|
||
Epub 2018 Jun 12
|
||
doi: 10.1055/a-0592-7925.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29895082" target="_blank">29895082</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29140825">Recurrent Corneal Erosions Secondary to Use of Sleep Mask.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McGlumphy EJ,
|
||
Margo JA,
|
||
Jeng BH</span><br />
|
||
<span class="medgenPMjournal">Eye Contact Lens</span>
|
||
2018 Sep;44 Suppl 1:S368-S369.
|
||
doi: 10.1097/ICL.0000000000000444.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29140825" target="_blank">29140825</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28264136">Phototherapeutic Keratectomy: Science and Art.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wilson SE,
|
||
Marino GK,
|
||
Medeiros CS,
|
||
Santhiago MR</span><br />
|
||
<span class="medgenPMjournal">J Refract Surg</span>
|
||
2017 Mar 1;33(3):203-210.
|
||
doi: 10.3928/1081597X-20161123-01.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28264136" target="_blank">28264136</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/5267187">Recurrent corneal erosions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Boruchoff SA</span><br />
|
||
<span class="medgenPMjournal">Am J Optom Arch Am Acad Optom</span>
|
||
1970 May;47(5):413-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/5267187" target="_blank">5267187</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Recurrent%20corneal%20erosions%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (44)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/31306672">Phototherapeutic keratectomy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nagpal R,
|
||
Maharana PK,
|
||
Roop P,
|
||
Murthy SI,
|
||
Rapuano CJ,
|
||
Titiyal JS,
|
||
Vajpayee RB,
|
||
Sharma N</span><br />
|
||
<span class="medgenPMjournal">Surv Ophthalmol</span>
|
||
2020 Jan-Feb;65(1):79-108.
|
||
Epub 2019 Jul 12
|
||
doi: 10.1016/j.survophthal.2019.07.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31306672" target="_blank">31306672</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29985545">Interventions for recurrent corneal erosions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Watson SL,
|
||
Leung V</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2018 Jul 9;7(7):CD001861.
|
||
doi: 10.1002/14651858.CD001861.pub4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29985545" target="_blank">29985545</a><a href="/pmc/articles/PMC6513638" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28264136">Phototherapeutic Keratectomy: Science and Art.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wilson SE,
|
||
Marino GK,
|
||
Medeiros CS,
|
||
Santhiago MR</span><br />
|
||
<span class="medgenPMjournal">J Refract Surg</span>
|
||
2017 Mar 1;33(3):203-210.
|
||
doi: 10.3928/1081597X-20161123-01.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28264136" target="_blank">28264136</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22972054">Interventions for recurrent corneal erosions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Watson SL,
|
||
Lee MH,
|
||
Barker NH</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2012 Sep 12;(9):CD001861.
|
||
doi: 10.1002/14651858.CD001861.pub3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22972054" target="_blank">22972054</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/6973234">Recurrent corneal erosions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Stasiuk RM,
|
||
Robertson I</span><br />
|
||
<span class="medgenPMjournal">Trans Ophthalmol Soc N Z</span>
|
||
1981;33:147-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/6973234" target="_blank">6973234</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Recurrent%20corneal%20erosions%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (61)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37490883">Safety and Efficacy of the Phototherapeutic Keratectomy for Treatment of Recurrent Corneal Erosions: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chen S,
|
||
Chu X,
|
||
Zhang C,
|
||
Jia Z,
|
||
Yang L,
|
||
Yang R,
|
||
Huang Y,
|
||
Zhao S</span><br />
|
||
<span class="medgenPMjournal">Ophthalmic Res</span>
|
||
2023;66(1):1114-1127.
|
||
Epub 2023 Jul 25
|
||
doi: 10.1159/000533160.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37490883" target="_blank">37490883</a><a href="/pmc/articles/PMC10614516" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35326011">Transepithelial phototherapeutic keratectomy for post-traumatic recurrent corneal erosions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang R,
|
||
Wang Q,
|
||
Li J,
|
||
Sun L,
|
||
Jhanji V,
|
||
Jiang J,
|
||
Zhang M</span><br />
|
||
<span class="medgenPMjournal">Indian J Ophthalmol</span>
|
||
2022 Apr;70(4):1186-1189.
|
||
doi: 10.4103/ijo.IJO_2340_21.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35326011" target="_blank">35326011</a><a href="/pmc/articles/PMC9240583" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33229661">Phototherapeutic keratectomy: Indications, methods and decision making.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Deshmukh R,
|
||
Reddy JC,
|
||
Rapuano CJ,
|
||
Vaddavalli PK</span><br />
|
||
<span class="medgenPMjournal">Indian J Ophthalmol</span>
|
||
2020 Dec;68(12):2856-2866.
|
||
doi: 10.4103/ijo.IJO_1524_20.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33229661" target="_blank">33229661</a><a href="/pmc/articles/PMC7856965" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31306672">Phototherapeutic keratectomy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nagpal R,
|
||
Maharana PK,
|
||
Roop P,
|
||
Murthy SI,
|
||
Rapuano CJ,
|
||
Titiyal JS,
|
||
Vajpayee RB,
|
||
Sharma N</span><br />
|
||
<span class="medgenPMjournal">Surv Ophthalmol</span>
|
||
2020 Jan-Feb;65(1):79-108.
|
||
Epub 2019 Jul 12
|
||
doi: 10.1016/j.survophthal.2019.07.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31306672" target="_blank">31306672</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7825413">Treatment of recurrent corneal erosions with the excimer laser.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ohman L,
|
||
Fagerholm P,
|
||
Tengroth B</span><br />
|
||
<span class="medgenPMjournal">Acta Ophthalmol (Copenh)</span>
|
||
1994 Aug;72(4):461-3.
|
||
doi: 10.1111/j.1755-3768.1994.tb02797.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7825413" target="_blank">7825413</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Recurrent%20corneal%20erosions%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (30)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/30572441">Corneal dysplastic melanosis associated with recurrent corneal erosions: A case report.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lee HK,
|
||
Lee C,
|
||
Kim MK</span><br />
|
||
<span class="medgenPMjournal">Medicine (Baltimore)</span>
|
||
2018 Dec;97(51):e13367.
|
||
doi: 10.1097/MD.0000000000013367.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30572441" target="_blank">30572441</a><a href="/pmc/articles/PMC6319972" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29985545">Interventions for recurrent corneal erosions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Watson SL,
|
||
Leung V</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2018 Jul 9;7(7):CD001861.
|
||
doi: 10.1002/14651858.CD001861.pub4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29985545" target="_blank">29985545</a><a href="/pmc/articles/PMC6513638" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22402249">Franceschetti hereditary recurrent corneal erosion.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lisch W,
|
||
Bron AJ,
|
||
Munier FL,
|
||
Schorderet DF,
|
||
Tiab L,
|
||
Lange C,
|
||
Saikia P,
|
||
Reinhard T,
|
||
Weiss JS,
|
||
Gundlach E,
|
||
Pleyer U,
|
||
Lisch C,
|
||
Auw-Haedrich C</span><br />
|
||
<span class="medgenPMjournal">Am J Ophthalmol</span>
|
||
2012 Jun;153(6):1073-81.e4.
|
||
Epub 2012 Mar 7
|
||
doi: 10.1016/j.ajo.2011.12.011.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22402249" target="_blank">22402249</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19427699">Recurrent corneal erosions treated with anterior stromal puncture by neodymium: yttrium-aluminum-garnet laser.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tsai TY,
|
||
Tsai TH,
|
||
Hu FR,
|
||
Hou YC</span><br />
|
||
<span class="medgenPMjournal">Ophthalmology</span>
|
||
2009 Jul;116(7):1296-300.
|
||
Epub 2009 May 8
|
||
doi: 10.1016/j.ophtha.2009.01.037.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19427699" target="_blank">19427699</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7260010">Prevalence of map-dot-fingerprint changes in the cornea.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Werblin TP,
|
||
Hirst LW,
|
||
Stark WJ,
|
||
Maumenee IH</span><br />
|
||
<span class="medgenPMjournal">Br J Ophthalmol</span>
|
||
1981 Jun;65(6):401-9.
|
||
doi: 10.1136/bjo.65.6.401.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7260010" target="_blank">7260010</a><a href="/pmc/articles/PMC1039533" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Recurrent%20corneal%20erosions%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (26)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/37490883">Safety and Efficacy of the Phototherapeutic Keratectomy for Treatment of Recurrent Corneal Erosions: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chen S,
|
||
Chu X,
|
||
Zhang C,
|
||
Jia Z,
|
||
Yang L,
|
||
Yang R,
|
||
Huang Y,
|
||
Zhao S</span><br />
|
||
<span class="medgenPMjournal">Ophthalmic Res</span>
|
||
2023;66(1):1114-1127.
|
||
Epub 2023 Jul 25
|
||
doi: 10.1159/000533160.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37490883" target="_blank">37490883</a><a href="/pmc/articles/PMC10614516" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29985545">Interventions for recurrent corneal erosions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Watson SL,
|
||
Leung V</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2018 Jul 9;7(7):CD001861.
|
||
doi: 10.1002/14651858.CD001861.pub4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29985545" target="_blank">29985545</a><a href="/pmc/articles/PMC6513638" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25803325">Corneal collagen cross-linking for treating keratoconus.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sykakis E,
|
||
Karim R,
|
||
Evans JR,
|
||
Bunce C,
|
||
Amissah-Arthur KN,
|
||
Patwary S,
|
||
McDonnell PJ,
|
||
Hamada S</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2015 Mar 24;2015(3):CD010621.
|
||
doi: 10.1002/14651858.CD010621.pub2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25803325" target="_blank">25803325</a><a href="/pmc/articles/PMC10645161" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22972054">Interventions for recurrent corneal erosions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Watson SL,
|
||
Lee MH,
|
||
Barker NH</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2012 Sep 12;(9):CD001861.
|
||
doi: 10.1002/14651858.CD001861.pub3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22972054" target="_blank">22972054</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17943758">Interventions for recurrent corneal erosions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Watson SL,
|
||
Barker NH</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2007 Oct 17;(4):CD001861.
|
||
doi: 10.1002/14651858.CD001861.pub2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17943758" target="_blank">17943758</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Recurrent%20corneal%20erosions%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (6)</a></div></div>
|
||
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|
||
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|
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