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<!--
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||
UID=45815
|
||
ConceptID=C0031099
|
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-->
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||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Periodontitis</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>45815</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0031099</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Periodontitides</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Periodontitis (41565005)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0000704">HP:0000704</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0005076" target="_blank">MONDO:0005076</a></td></tr>
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</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">Inflammation of the periodontium. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0031099[DISCUI]&test_type=Clinical&redirect=true" ref="ncbi_uid=45815">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=45815" ref="ncbi_uid=45815">V</a></span></span><span class="TLline">Periodontitis</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/867388" ref="tree=MeSH" title="MedGen record for Abnormality of the immune system">Abnormality of the immune system</a></span><ul><li><span class="TLline"><a href="/medgen/869194" ref="tree=MeSH" title="MedGen record for Abnormality of immune system physiology">Abnormality of immune system physiology</a></span><ul><li><span class="TLline"><a href="/medgen/868411" ref="tree=MeSH" title="MedGen record for Abnormal inflammatory response">Abnormal inflammatory response</a></span><ul><li><span class="TLline"><a href="/medgen/868409" ref="tree=MeSH" title="MedGen record for Increased inflammatory response">Increased inflammatory response</a></span><ul><li><span class="matched_ds">Periodontitis</span><ul><li><span class="TLline"><a href="/medgen/1319" ref="tree=MeSH" title="MedGen record for Acute pericementitis">Acute pericementitis</a></span></li><li><span class="TLline"><a href="/medgen/120593" ref="tree=MeSH" title="MedGen record for Adult periodontitis">Adult periodontitis</a></span></li><li><span class="TLline"><a href="/medgen/10661" ref="tree=MeSH" title="MedGen record for Aggressive periodontitis">Aggressive periodontitis</a></span></li><li><span class="TLline"><a href="/medgen/869140" ref="tree=MeSH" title="MedGen record for Generalized periodontitis">Generalized periodontitis</a></span></li><li><span class="TLline"><a href="/medgen/869139" ref="tree=MeSH" title="MedGen record for Localized periodontitis">Localized periodontitis</a></span></li><li><span class="TLline"><a href="/medgen/45396" ref="tree=MeSH" title="MedGen record for Periapical periodontitis">Periapical periodontitis</a></span><ul><li><span class="TLline"><a href="/medgen/45395" ref="tree=MeSH" title="MedGen record for Periapical granuloma">Periapical granuloma</a></span></li><li><span class="TLline"><a href="/medgen/10652" ref="tree=MeSH" title="MedGen record for Suppurative periapical periodontitis">Suppurative periapical periodontitis</a></span><ul><li><span class="TLline"><a href="/medgen/120592" ref="tree=MeSH" title="MedGen record for Periapical abscess with sinus tract">Periapical abscess with sinus tract</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/14687" ref="tree=MeSH" title="MedGen record for Periodontal abscess">Periodontal abscess</a></span></li><li><span class="TLline"><a href="/medgen/45814" ref="tree=MeSH" title="MedGen record for Periodontal pocket">Periodontal pocket</a></span></li><li><span class="TLline"><a href="/medgen/871390" ref="tree=MeSH" title="MedGen record for Severe periodontitis">Severe periodontitis</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_3347"><div><strong>Chédiak-Higashi syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>3347</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0007965</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Chediak-Higashi syndrome (CHS) is characterized by partial oculocutaneous albinism (OCA), immunodeficiency, a mild bleeding tendency, and late adolescent- to adult-onset neurologic manifestations (e.g., learning difficulties, peripheral neuropathy, ataxia, and parkinsonism). While present in nearly all individuals with CHS, these clinical findings vary in severity. Of note, all individuals with CHS are at risk of developing neurologic manifestations and hemophagocytic lymphohistiocytosis (HLH). Individuals with severe childhood-onset presentations are considered to have "classic" CHS, whereas individuals with milder adolescent- to adult-onset presentations are considered to have "atypical" CHS. Because of the considerable overlap between classic CHS and atypical CHS, the disorder is best understood as a continuum of severe to milder phenotypes, with the universal feature being the pathognomonic giant granules within leukocytes observed on peripheral blood smear.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/3347">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_82790"><div><strong>Ehlers-Danlos syndrome, type 4</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>82790</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0268338</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Vascular Ehlers-Danlos syndrome (vEDS) is characterized by arterial, intestinal, and/or uterine fragility; thin, translucent skin; easy bruising; characteristic facial appearance (thin vermilion of the lips, micrognathia, narrow nose, prominent eyes); and an aged appearance to the extremities, particularly the hands. Vascular dissection or rupture, gastrointestinal perforation, or organ rupture are the presenting signs in most adults with vEDS. Arterial rupture may be preceded by aneurysm, arteriovenous fistulae, or dissection but also may occur spontaneously. The majority (60%) of individuals with vEDS who are diagnosed before age 18 years are identified because of a positive family history. Neonates may present with clubfoot, hip dislocation, limb deficiency, and/or amniotic bands. Approximately half of children tested for vEDS in the absence of a positive family history present with a major complication at an average age of 11 years. Four minor diagnostic features – distal joint hypermobility, easy bruising, thin skin, and clubfeet – are most often present in those children ascertained without a major complication.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/82790">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_98310"><div><strong>Leukocyte adhesion deficiency 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>98310</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0398738</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Leukocyte adhesion deficiency (LAD) is an autosomal recessive disorder of neutrophil function resulting from a deficiency of the beta-2 integrin subunit of the leukocyte cell adhesion molecule. The leukocyte cell adhesion molecule is present on the surface of peripheral blood mononuclear leukocytes and granulocytes and mediates cell-cell and cell-extracellular matrix adhesion. LAD is characterized by recurrent bacterial infections; impaired pus formation and wound healing; abnormalities of a wide variety of adhesion-dependent functions of granulocytes, monocytes, and lymphocytes; and a lack of beta-2/alpha-L, beta-2/alpha-M, and beta-2/alpha-X expression. Genetic Heterogeneity of Leukocyte Adhesion Deficiency Also see LAD2 (266265), caused by mutation in the SLC35C1 gene (605881), and LAD3 (612840), caused by mutation in the FERMT3 gene (607901).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/98310">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_96022"><div><strong>Leukocyte adhesion deficiency type II</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>96022</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0398739</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Congenital disorder of glycosylation type IIc (CDG2C) is an autosomal recessive disorder characterized by moderate to severe psychomotor retardation, mild dysmorphism, and impaired neutrophil motility. It is a member of a group of disorders with a defect in the processing of protein-bound glycans. For a general overview of congenital disorders of glycosylation (CDGs), see CDG1A (212065) and CDG2A (212066). Frydman (1996) contended that the neutrophil defect in CDG2C, which has been referred to as 'leukocyte adhesion deficiency type II' (LAD2), is a manifestation of the disorder and that there are no cases of 'primary' LAD II. Etzioni and Harlan (1999) provided a comprehensive review of both leukocyte adhesion deficiency-1 (LAD1; 116920) and LAD2. While the functional neutrophil studies are similar in the 2 LADs, the clinical course is milder in LAD2. Furthermore, patients with LAD2 present other abnormal features, such as growth and mental retardation, which are related to the primary defect in fucose metabolism. Delayed separation of the umbilical cord occurs in LAD1. For a discussion of genetic heterogeneity of LAD, see 116920.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/96022">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_96060"><div><strong>Kindler syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>96060</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0406557</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Kindler syndrome (KS), a rare subtype of inherited epidermolysis bullosa, is characterized by skin fragility and acral blister formation beginning at birth, diffuse cutaneous atrophy, photosensitivity (most prominent during childhood and usually decreasing after adolescence), poikiloderma, diffuse palmoplantar hyperkeratosis, and pseudosyndactyly. Mucosal manifestations are also common and include hemorrhagic mucositis and gingivitis, periodontal disease, premature loss of teeth, and labial leukokeratosis. Other mucosal findings can include ectropion, urethral stenosis, and severe phimosis. Severe long-term complications of KS include periodontitis, mucosal strictures, and aggressive squamous cell carcinomas. Manifestations can range from mild to severe.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/96060">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_98149"><div><strong>Geroderma osteodysplastica</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>98149</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0432255</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Geroderma osteodysplasticum (GO) is an autosomal recessive disorder characterized by skin wrinkling limited to the dorsa of hands and feet and to the abdomen, bowed long bones, and osteopenia with frequent fractures. There is a distinctive facial appearance with droopy skin at the cheeks, maxillary hypoplasia, and large ears. Adult patients appear prematurely aged (summary by Rajab et al., 2008).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/98149">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_374912"><div><strong>Hermansky-Pudlak syndrome 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>374912</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1842362</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hermansky-Pudlak syndrome (HPS) is characterized by oculocutaneous albinism, a bleeding diathesis, and, in some individuals, pulmonary fibrosis, granulomatous colitis, and/or immunodeficiency. Ocular findings include nystagmus, reduced iris pigment, reduced retinal pigment, foveal hypoplasia with significant reduction in visual acuity (usually in the range of 20/50 to 20/400), and strabismus in many individuals. Hair color ranges from white to brown; skin color ranges from white to olive and is usually at least a shade lighter than that of other family members. The bleeding diathesis can result in variable degrees of bruising, epistaxis, gingival bleeding, postpartum hemorrhage, colonic bleeding, and prolonged bleeding with menses or after tooth extraction, circumcision, and/or other surgeries. Pulmonary fibrosis, colitis, and/or neutropenia have been reported in individuals with pathogenic variants in some HPS-related genes. Pulmonary fibrosis, a restrictive lung disease, typically causes symptoms in the early 30s and can progress to death within a decade. Granulomatous colitis is severe in about 15% of affected individuals. Neutropenia and/or immune defects occur primarily in individuals with pathogenic variants in AP3B1 and AP3D1.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/374912">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_369859"><div><strong>Plasminogen deficiency, type I</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>369859</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1968804</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Congenital plasminogen deficiency is a rare autosomal recessive disorder characterized clinically by chronic mucosal pseudomembranous lesions consisting of subepithelial fibrin deposition and inflammation. The most common clinical manifestation is ligneous ('wood-like') conjunctivitis, a redness and subsequent formation of pseudomembranes mostly on the palpebral surfaces of the eye that progress to white, yellow-white, or red thick masses with a wood-like consistency that replace the normal mucosa. The lesions may be triggered by local injury and/or infection and often recur after local excision. Pseudomembranous lesions of other mucous membranes often occur in the mouth, nasopharynx, trachea, and female genital tract. Some affected children also have congenital occlusive hydrocephalus. A slightly increased female:male ratio has been observed (1.4:1 to 2:1) (Schuster and Seregard, 2003; Tefs et al., 2006). Type I plasminogen deficiency is characterized by decreased serum plasminogen activity, decreased plasminogen antigen levels, and clinical symptoms, whereas type II plasminogen deficiency, also known as 'dysplasminogenemia,' is characterized by decreased plasminogen activity with normal or slightly reduced antigen levels. Patients with type II deficiency are usually asymptomatic. Ligneous conjunctivitis and pseudomembranous formation has only been associated with type I plasminogen deficiency. Presumably, normal amounts of plasminogen antigen with decreased activity, as seen in type II, is sufficient for normal wound healing (Schuster and Seregard, 2003).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/369859">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_777137"><div><strong>Chronic familial neutropenia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>777137</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3665676</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/777137">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_934648"><div><strong>Ehlers-Danlos syndrome, periodontal type 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>934648</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4310681</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Periodontal Ehlers-Danlos syndrome (pEDS) is characterized by distinct oral manifestations. Periodontal tissue breakdown beginning in the teens results in premature loss of teeth. Lack of attached gingiva and thin and fragile gums lead to gingival recession. Connective tissue abnormalities of pEDS typically include easy bruising, pretibial plaques, distal joint hypermobility, hoarse voice, and less commonly manifestations such as organ or vessel rupture. Since the first descriptions of pEDS in the 1970s, 148 individuals have been reported in the literature; however, future in-depth descriptions of non-oral manifestations in newly diagnosed individuals with a molecularly confirmed diagnosis of pEDS will be important to further define the clinical features.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/934648">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1642148"><div><strong>Ehlers-Danlos syndrome, periodontal type 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1642148</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4551499</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Periodontal Ehlers-Danlos syndrome (pEDS) is characterized by distinct oral manifestations. Periodontal tissue breakdown beginning in the teens results in premature loss of teeth. Lack of attached gingiva and thin and fragile gums lead to gingival recession. Connective tissue abnormalities of pEDS typically include easy bruising, pretibial plaques, distal joint hypermobility, hoarse voice, and less commonly manifestations such as organ or vessel rupture. Since the first descriptions of pEDS in the 1970s, 148 individuals have been reported in the literature; however, future in-depth descriptions of non-oral manifestations in newly diagnosed individuals with a molecularly confirmed diagnosis of pEDS will be important to further define the clinical features.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1642148">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1632001"><div><strong>Ehlers-Danlos syndrome, classic-like, 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1632001</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4693870</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Ehlers-Danlos syndrome classic-like-2 (EDSCLL2) is characterized by severe joint and skin laxity, osteoporosis involving the hips and spine, osteoarthritis, soft redundant skin that can be acrogeria-like, delayed wound healing with abnormal atrophic scarring, and shoulder, hip, knee, and ankle dislocations. Variable features include gastrointestinal and genitourinary manifestations, such as bowel rupture, gut dysmotility, cryptorchidism, and hernias; vascular complications, such as mitral valve prolapse and aortic root dilation; and skeletal anomalies (Blackburn et al., 2018). For a discussion of genetic heterogeneity of classic-like Ehlers-Danlos syndrome, see 606408. For a discussion of the classification of EDS, see 130000.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1632001">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1782909"><div><strong>Odontochondrodysplasia 2 with hearing loss and diabetes</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1782909</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5543275</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Odontochondrodysplasia-2 with hearing loss and diabetes (ODCD2) is characterized by growth retardation with proportionate short stature, dentinogenesis imperfecta, sensorineural hearing loss, insulin-dependent diabetes, and mild intellectual disability (Cauwels et al., 2005; Lekszas et al., 2020). For a discussion of genetic heterogeneity of ODCD, see ODCD1 (184260).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1782909">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_777137" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Chronic familial neutropenia</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_3347" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Chédiak-Higashi syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1632001" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Ehlers-Danlos syndrome, classic-like, 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1642148" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Ehlers-Danlos syndrome, periodontal type 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_934648" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Ehlers-Danlos syndrome, periodontal type 2</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (13)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_82790" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Ehlers-Danlos syndrome, type 4</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_98149" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Geroderma osteodysplastica</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_374912" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hermansky-Pudlak syndrome 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_96060" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Kindler syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_98310" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Leukocyte adhesion deficiency 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_96022" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Leukocyte adhesion deficiency type II</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1782909" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Odontochondrodysplasia 2 with hearing loss and diabetes</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_369859" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Plasminogen deficiency, type I</a></div></span></div></div>
|
||
</div>
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|
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<div class="portlet mgSection" id="ID_105">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
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<div class="nl"><a target="_blank" href="/pubmed/37271498">Prevention and treatment of peri-implant diseases-The EFP S3 level clinical practice guideline.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Herrera D,
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Berglundh T,
|
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Schwarz F,
|
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Chapple I,
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Jepsen S,
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Sculean A,
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Kebschull M,
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Papapanou PN,
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Tonetti MS,
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Sanz M;
|
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EFP workshop participants and methodological consultant</span><br />
|
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<span class="medgenPMjournal">J Clin Periodontol</span>
|
||
2023 Jun;50 Suppl 26:4-76.
|
||
Epub 2023 Jun 4
|
||
doi: 10.1111/jcpe.13823.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37271498" target="_blank">37271498</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34839889">Current Concepts in the Management of Periodontitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kwon T,
|
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Lamster IB,
|
||
Levin L</span><br />
|
||
<span class="medgenPMjournal">Int Dent J</span>
|
||
2021 Dec;71(6):462-476.
|
||
Epub 2021 Feb 19
|
||
doi: 10.1111/idj.12630.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34839889" target="_blank">34839889</a><a href="/pmc/articles/PMC9275292" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32383274">Treatment of stage I-III periodontitis-The EFP S3 level clinical practice guideline.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sanz M,
|
||
Herrera D,
|
||
Kebschull M,
|
||
Chapple I,
|
||
Jepsen S,
|
||
Beglundh T,
|
||
Sculean A,
|
||
Tonetti MS;
|
||
EFP Workshop Participants and Methodological Consultants</span><br />
|
||
<span class="medgenPMjournal">J Clin Periodontol</span>
|
||
2020 Jul;47 Suppl 22(Suppl 22):4-60.
|
||
doi: 10.1111/jcpe.13290.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32383274" target="_blank">32383274</a><a href="/pmc/articles/PMC7891343" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22periodontitis%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (1865)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35244969">Interconnection of periodontal disease and comorbidities: Evidence, mechanisms, and implications.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hajishengallis G</span><br />
|
||
<span class="medgenPMjournal">Periodontol 2000</span>
|
||
2022 Jun;89(1):9-18.
|
||
Epub 2022 Mar 4
|
||
doi: 10.1111/prd.12430.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35244969" target="_blank">35244969</a><a href="/pmc/articles/PMC9018559" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34839889">Current Concepts in the Management of Periodontitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kwon T,
|
||
Lamster IB,
|
||
Levin L</span><br />
|
||
<span class="medgenPMjournal">Int Dent J</span>
|
||
2021 Dec;71(6):462-476.
|
||
Epub 2021 Feb 19
|
||
doi: 10.1111/idj.12630.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34839889" target="_blank">34839889</a><a href="/pmc/articles/PMC9275292" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29926952">Staging and grading of periodontitis: Framework and proposal of a new classification and case definition.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tonetti MS,
|
||
Greenwell H,
|
||
Kornman KS</span><br />
|
||
<span class="medgenPMjournal">J Periodontol</span>
|
||
2018 Jun;89 Suppl 1:S159-S172.
|
||
doi: 10.1002/JPER.18-0006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29926952" target="_blank">29926952</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29926951">Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Papapanou PN,
|
||
Sanz M,
|
||
Buduneli N,
|
||
Dietrich T,
|
||
Feres M,
|
||
Fine DH,
|
||
Flemmig TF,
|
||
Garcia R,
|
||
Giannobile WV,
|
||
Graziani F,
|
||
Greenwell H,
|
||
Herrera D,
|
||
Kao RT,
|
||
Kebschull M,
|
||
Kinane DF,
|
||
Kirkwood KL,
|
||
Kocher T,
|
||
Kornman KS,
|
||
Kumar PS,
|
||
Loos BG,
|
||
Machtei E,
|
||
Meng H,
|
||
Mombelli A,
|
||
Needleman I,
|
||
Offenbacher S,
|
||
Seymour GJ,
|
||
Teles R,
|
||
Tonetti MS</span><br />
|
||
<span class="medgenPMjournal">J Periodontol</span>
|
||
2018 Jun;89 Suppl 1:S173-S182.
|
||
doi: 10.1002/JPER.17-0721.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29926951" target="_blank">29926951</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24651336">Causes and management of post-treatment apical periodontitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Siqueira JF Jr,
|
||
Rôças IN,
|
||
Ricucci D,
|
||
Hülsmann M</span><br />
|
||
<span class="medgenPMjournal">Br Dent J</span>
|
||
2014 Mar;216(6):305-12.
|
||
doi: 10.1038/sj.bdj.2014.200.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24651336" target="_blank">24651336</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Periodontitis%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (14942)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36749410">Association between periodontitis and breast cancer: two-sample Mendelian randomization study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ding M,
|
||
Zhang Z,
|
||
Chen Z,
|
||
Song J,
|
||
Wang B,
|
||
Jin F</span><br />
|
||
<span class="medgenPMjournal">Clin Oral Investig</span>
|
||
2023 Jun;27(6):2843-2849.
|
||
Epub 2023 Feb 7
|
||
doi: 10.1007/s00784-023-04874-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36749410" target="_blank">36749410</a><a href="/pmc/articles/PMC10264523" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34839889">Current Concepts in the Management of Periodontitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kwon T,
|
||
Lamster IB,
|
||
Levin L</span><br />
|
||
<span class="medgenPMjournal">Int Dent J</span>
|
||
2021 Dec;71(6):462-476.
|
||
Epub 2021 Feb 19
|
||
doi: 10.1111/idj.12630.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34839889" target="_blank">34839889</a><a href="/pmc/articles/PMC9275292" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30198129">Lifestyle and periodontitis: The emergence of personalized periodontics.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bartold PM</span><br />
|
||
<span class="medgenPMjournal">Periodontol 2000</span>
|
||
2018 Oct;78(1):7-11.
|
||
doi: 10.1111/prd.12237.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30198129" target="_blank">30198129</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29926952">Staging and grading of periodontitis: Framework and proposal of a new classification and case definition.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tonetti MS,
|
||
Greenwell H,
|
||
Kornman KS</span><br />
|
||
<span class="medgenPMjournal">J Periodontol</span>
|
||
2018 Jun;89 Suppl 1:S159-S172.
|
||
doi: 10.1002/JPER.18-0006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29926952" target="_blank">29926952</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28317565">Periodontal Microbiology.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Harvey JD</span><br />
|
||
<span class="medgenPMjournal">Dent Clin North Am</span>
|
||
2017 Apr;61(2):253-269.
|
||
doi: 10.1016/j.cden.2016.11.005.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28317565" target="_blank">28317565</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Periodontitis%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (6798)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33811981">Regenerative Endodontic Procedures for the Treatment of Necrotic Mature Teeth with Apical Periodontitis: A Systematic Review and Meta-analysis of Randomized Controlled Trials.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Glynis A,
|
||
Foschi F,
|
||
Kefalou I,
|
||
Koletsi D,
|
||
Tzanetakis GN</span><br />
|
||
<span class="medgenPMjournal">J Endod</span>
|
||
2021 Jun;47(6):873-882.
|
||
Epub 2021 Mar 31
|
||
doi: 10.1016/j.joen.2021.03.015.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33811981" target="_blank">33811981</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32708032">Vitamin D and Periodontitis: A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Machado V,
|
||
Lobo S,
|
||
Proença L,
|
||
Mendes JJ,
|
||
Botelho J</span><br />
|
||
<span class="medgenPMjournal">Nutrients</span>
|
||
2020 Jul 22;12(8)
|
||
doi: 10.3390/nu12082177.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32708032" target="_blank">32708032</a><a href="/pmc/articles/PMC7468917" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31429666">Periodontal Medicine: 100 Years of Progress.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Beck JD,
|
||
Papapanou PN,
|
||
Philips KH,
|
||
Offenbacher S</span><br />
|
||
<span class="medgenPMjournal">J Dent Res</span>
|
||
2019 Sep;98(10):1053-1062.
|
||
doi: 10.1177/0022034519846113.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31429666" target="_blank">31429666</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27759881">Endodontic procedures for retreatment of periapical lesions.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Del Fabbro M,
|
||
Corbella S,
|
||
Sequeira-Byron P,
|
||
Tsesis I,
|
||
Rosen E,
|
||
Lolato A,
|
||
Taschieri S</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2016 Oct 19;10(10):CD005511.
|
||
doi: 10.1002/14651858.CD005511.pub3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27759881" target="_blank">27759881</a><a href="/pmc/articles/PMC6461161" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25429029">Diabetes and periodontal therapy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pihlstrom BL,
|
||
Buse JB</span><br />
|
||
<span class="medgenPMjournal">J Am Dent Assoc</span>
|
||
2014 Dec;145(12):1208-10.
|
||
doi: 10.14219/jada.2014.112.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25429029" target="_blank">25429029</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Periodontitis%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (8787)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/32489774">Periodontitis and Cardiovascular Diseases. Consensus Report.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sanz M,
|
||
Del Castillo AM,
|
||
Jepsen S,
|
||
Gonzalez-Juanatey JR,
|
||
D'Aiuto F,
|
||
Bouchard P,
|
||
Chapple I,
|
||
Dietrich T,
|
||
Gotsman I,
|
||
Graziani F,
|
||
Herrera D,
|
||
Loos B,
|
||
Madianos P,
|
||
Michel JB,
|
||
Perel P,
|
||
Pieske B,
|
||
Shapira L,
|
||
Shechter M,
|
||
Tonetti M,
|
||
Vlachopoulos C,
|
||
Wimmer G</span><br />
|
||
<span class="medgenPMjournal">Glob Heart</span>
|
||
2020 Feb 3;15(1):1.
|
||
doi: 10.5334/gh.400.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32489774" target="_blank">32489774</a><a href="/pmc/articles/PMC7218770" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32385875">Effects of periodontal disease on glycemic control, complications, and incidence of diabetes mellitus.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Genco RJ,
|
||
Graziani F,
|
||
Hasturk H</span><br />
|
||
<span class="medgenPMjournal">Periodontol 2000</span>
|
||
2020 Jun;83(1):59-65.
|
||
doi: 10.1111/prd.12271.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32385875" target="_blank">32385875</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29656920">Effect of Smoking on Periodontitis: A Systematic Review and Meta-regression.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Leite FRM,
|
||
Nascimento GG,
|
||
Scheutz F,
|
||
López R</span><br />
|
||
<span class="medgenPMjournal">Am J Prev Med</span>
|
||
2018 Jun;54(6):831-841.
|
||
Epub 2018 Apr 12
|
||
doi: 10.1016/j.amepre.2018.02.014.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29656920" target="_blank">29656920</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25261053">Global burden of severe periodontitis in 1990-2010: a systematic review and meta-regression.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kassebaum NJ,
|
||
Bernabé E,
|
||
Dahiya M,
|
||
Bhandari B,
|
||
Murray CJ,
|
||
Marcenes W</span><br />
|
||
<span class="medgenPMjournal">J Dent Res</span>
|
||
2014 Nov;93(11):1045-53.
|
||
Epub 2014 Sep 26
|
||
doi: 10.1177/0022034514552491.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25261053" target="_blank">25261053</a><a href="/pmc/articles/PMC4293771" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25185675">Definition, etiology, prevention and treatment of peri-implantitis--a review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Smeets R,
|
||
Henningsen A,
|
||
Jung O,
|
||
Heiland M,
|
||
Hammächer C,
|
||
Stein JM</span><br />
|
||
<span class="medgenPMjournal">Head Face Med</span>
|
||
2014 Sep 3;10:34.
|
||
doi: 10.1186/1746-160X-10-34.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25185675" target="_blank">25185675</a><a href="/pmc/articles/PMC4164121" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Periodontitis%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5167)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38347510">Association of cardiovascular health and periodontitis: a population-based study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Qu H,
|
||
Zhang S</span><br />
|
||
<span class="medgenPMjournal">BMC Public Health</span>
|
||
2024 Feb 12;24(1):438.
|
||
doi: 10.1186/s12889-024-18001-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38347510" target="_blank">38347510</a><a href="/pmc/articles/PMC10860246" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35341892">Artificial intelligence for caries and periapical periodontitis detection.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Li S,
|
||
Liu J,
|
||
Zhou Z,
|
||
Zhou Z,
|
||
Wu X,
|
||
Li Y,
|
||
Wang S,
|
||
Liao W,
|
||
Ying S,
|
||
Zhao Z</span><br />
|
||
<span class="medgenPMjournal">J Dent</span>
|
||
2022 Jul;122:104107.
|
||
Epub 2022 Mar 24
|
||
doi: 10.1016/j.jdent.2022.104107.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35341892" target="_blank">35341892</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32761938">Psychosocial oral health-related quality of life impact: A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Su N,
|
||
van Wijk A,
|
||
Visscher CM</span><br />
|
||
<span class="medgenPMjournal">J Oral Rehabil</span>
|
||
2021 Mar;48(3):282-292.
|
||
Epub 2020 Aug 14
|
||
doi: 10.1111/joor.13064.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32761938" target="_blank">32761938</a><a href="/pmc/articles/PMC7984127" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12102704">Periodontal diseases in Africa.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Baelum V,
|
||
Scheutz F</span><br />
|
||
<span class="medgenPMjournal">Periodontol 2000</span>
|
||
2002;29:79-103.
|
||
doi: 10.1034/j.1600-0757.2002.290105.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12102704" target="_blank">12102704</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8260005">Diagnostic potential of host response mediators.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Offenbacher S,
|
||
Collins JG,
|
||
Heasman PA</span><br />
|
||
<span class="medgenPMjournal">Adv Dent Res</span>
|
||
1993 Aug;7(2):175-81.
|
||
doi: 10.1177/08959374930070020801.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8260005" target="_blank">8260005</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Periodontitis%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (8530)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/33811981">Regenerative Endodontic Procedures for the Treatment of Necrotic Mature Teeth with Apical Periodontitis: A Systematic Review and Meta-analysis of Randomized Controlled Trials.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Glynis A,
|
||
Foschi F,
|
||
Kefalou I,
|
||
Koletsi D,
|
||
Tzanetakis GN</span><br />
|
||
<span class="medgenPMjournal">J Endod</span>
|
||
2021 Jun;47(6):873-882.
|
||
Epub 2021 Mar 31
|
||
doi: 10.1016/j.joen.2021.03.015.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33811981" target="_blank">33811981</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33274850">The impact of vaping on periodontitis: A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Figueredo CA,
|
||
Abdelhay N,
|
||
Figueredo CM,
|
||
Catunda R,
|
||
Gibson MP</span><br />
|
||
<span class="medgenPMjournal">Clin Exp Dent Res</span>
|
||
2021 Jun;7(3):376-384.
|
||
Epub 2020 Dec 4
|
||
doi: 10.1002/cre2.360.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33274850" target="_blank">33274850</a><a href="/pmc/articles/PMC8204026" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32652980">Epidemiologic relationship between periodontitis and type 2 diabetes mellitus.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wu CZ,
|
||
Yuan YH,
|
||
Liu HH,
|
||
Li SS,
|
||
Zhang BW,
|
||
Chen W,
|
||
An ZJ,
|
||
Chen SY,
|
||
Wu YZ,
|
||
Han B,
|
||
Li CJ,
|
||
Li LJ</span><br />
|
||
<span class="medgenPMjournal">BMC Oral Health</span>
|
||
2020 Jul 11;20(1):204.
|
||
doi: 10.1186/s12903-020-01180-w.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32652980" target="_blank">32652980</a><a href="/pmc/articles/PMC7353775" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29656920">Effect of Smoking on Periodontitis: A Systematic Review and Meta-regression.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Leite FRM,
|
||
Nascimento GG,
|
||
Scheutz F,
|
||
López R</span><br />
|
||
<span class="medgenPMjournal">Am J Prev Med</span>
|
||
2018 Jun;54(6):831-841.
|
||
Epub 2018 Apr 12
|
||
doi: 10.1016/j.amepre.2018.02.014.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29656920" target="_blank">29656920</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25639826">Primary prevention of periodontitis: managing gingivitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chapple IL,
|
||
Van der Weijden F,
|
||
Doerfer C,
|
||
Herrera D,
|
||
Shapira L,
|
||
Polak D,
|
||
Madianos P,
|
||
Louropoulou A,
|
||
Machtei E,
|
||
Donos N,
|
||
Greenwell H,
|
||
Van Winkelhoff AJ,
|
||
Eren Kuru B,
|
||
Arweiler N,
|
||
Teughels W,
|
||
Aimetti M,
|
||
Molina A,
|
||
Montero E,
|
||
Graziani F</span><br />
|
||
<span class="medgenPMjournal">J Clin Periodontol</span>
|
||
2015 Apr;42 Suppl 16:S71-6.
|
||
doi: 10.1111/jcpe.12366.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25639826" target="_blank">25639826</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Periodontitis%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1119)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
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|
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|
||
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0031099%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C0031099%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (1)</a></li>
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<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0031099%5bDISCUI%5d" target="_blank">See all (1)</a></total></li>
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Periodontitis" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22periodontitis%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Periodontitis%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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<div class="portlet_content ln"><ul><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Periodontitis" target="_blank">MedlinePlus</a></li></ul></div>
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<a href="/pubmed/clinical?term=Periodontitis" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=1&linkpostotal=2" target="_blank">PubMed Clinical Queries</a>
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<a href="/pubmed?term=Periodontitis%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=2&linkpostotal=2" target="_blank">Reviews in PubMed</a>
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<a class="brieflinkpopperctrl" href="/clinvar?LinkName=medgen_clinvar&from_uid=45815" ref="log$=recordlinks">ClinVar</a>
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<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
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</li>
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<li class="brieflinkpopper">
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<a class="brieflinkpopperctrl" href="/gtr/tests?term=C0031099[DISCUI]" ref="log$=recordlinks">GTR</a>
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<div class="brieflinkpop offscreen_noflow">Related information in GTR</div>
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||
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<a class="brieflinkpopperctrl" href="/gtr/tests?term=C0031099[DISCUI]&test_type=Clinical" ref="log$=recordlinks">GTR(Clinical)</a>
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<a class="brieflinkpopperctrl" href="/pmc?LinkName=medgen_pmc&from_uid=45815" ref="log$=recordlinks">PMC Articles</a>
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<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory" sid="1" realname="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory" cmd="ClearHT" href="?cmd=ClearHT&" onclick="return false;" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory">
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Clear
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<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle" sid="1" realname="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOn" cmd="HTOff" href="?cmd=HTOff&" onclick="return false;" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.HistoryToggle">
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Turn Off
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Turn On
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<ul id="activity">
|
||
<li class="ra_rcd ralinkpopper two_line">
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||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67d366be84f3725e59c82fba">Periodontitis</a>
|
||
<div class="ralinkpop offscreen_noflow">Periodontitis<div class="brieflinkpopdesc"></div></div>
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<div class="tertiary">MedGen</div>
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