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<meta name="keywords" content="C0030283, cyst of pancreas, cyst of the pancreas, cyst, pancreatic, cysts, pancreatic, disease or syndrome, multiple pancreatic cysts, pancreas cyst, pancreatic cyst, pancreatic cysts, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A cyst of the pancreas that possess a lining of mucous epithelium." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
UID=45293
ConceptID=C0030283
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Pancreatic cysts</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>45293</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0030283</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
<td>Cyst, Pancreatic; Cysts, Pancreatic; Pancreatic Cyst; Pancreatic Cysts</td></tr>
<tr><td><span class="bold">SNOMED CT: </span></td>
<td>Pancreatic cyst (31258000); Cyst of pancreas (31258000)</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0001737">HP:0001737</a></td></tr>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">A cyst of the pancreas that possess a lining of mucous epithelium. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
</div>
<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Pancreatic cysts</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/3828" ref="tree=MeSH" title="MedGen record for Disorder of digestive system">Disorder of digestive system</a></span><ul><li><span class="TLline"><a href="/medgen/78584" ref="tree=MeSH" title="MedGen record for Abnormality of the digestive system">Abnormality of the digestive system</a></span><ul><li><span class="TLline"><a href="/medgen/867396" ref="tree=MeSH" title="MedGen record for Abnormality of the abdominal organs">Abnormality of the abdominal organs</a></span><ul><li><span class="TLline"><a href="/medgen/892541" ref="tree=MeSH" title="MedGen record for Abnormality of the pancreas">Abnormality of the pancreas</a></span><ul><li><span class="TLline"><a href="/medgen/868648" ref="tree=MeSH" title="MedGen record for Abnormal pancreas morphology">Abnormal pancreas morphology</a></span><ul><li><span class="matched_ds">Pancreatic cysts</span><ul><li><span class="TLline"><a href="/medgen/18280" ref="tree=MeSH" title="MedGen record for Pancreatic pseudocyst">Pancreatic pseudocyst</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_112">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln clinfeat">
<div class="divPopper rprt" id="rdis_42458"><div><strong>Von Hippel-Lindau syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>42458</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0019562</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Von Hippel-Lindau syndrome (VHL) is characterized by hemangioblastomas of the brain, spinal cord, and retina; renal cysts and clear cell renal cell carcinoma; pheochromocytoma and paraganglioma; pancreatic cysts and neuroendocrine tumors; endolymphatic sac tumors; and epididymal and broad ligament cystadenomas. Retinal hemangioblastomas may be the initial manifestation of VHL and can cause vision loss. Cerebellar hemangioblastomas may be associated with headache, vomiting, gait disturbances, or ataxia. Spinal hemangioblastomas and related syrinx usually present with pain. Sensory and motor loss may develop with cord compression. Renal cell carcinoma occurs in about 70% of individuals with VHL and is the leading cause of mortality. Pheochromocytomas can be asymptomatic but may cause sustained or episodic hypertension. Pancreatic lesions often remain asymptomatic and rarely cause endocrine or exocrine insufficiency. Endolymphatic sac tumors can cause hearing loss of varying severity, which can be a presenting symptom. Cystadenomas of the epididymis are relatively common. They rarely cause problems, unless bilateral, in which case they may result in infertility.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/42458">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_61235"><div><strong>Radial aplasia-thrombocytopenia syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>61235</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0175703</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Thrombocytopenia absent radius (TAR) syndrome is characterized by bilateral absence of the radii with the presence of both thumbs, and thrombocytopenia that is generally transient. Thrombocytopenia may be congenital or may develop within the first few weeks to months of life; in general, thrombocytopenic episodes decrease with age. Cow's milk allergy is common and can be associated with exacerbation of thrombocytopenia. Other anomalies of the skeleton (upper and lower limbs, ribs, and vertebrae), heart, and genitourinary system (renal anomalies and agenesis of uterus, cervix, and upper part of the vagina) can occur.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/61235">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_307142"><div><strong>Orofaciodigital syndrome I</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>307142</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1510460</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Oral-facial-digital syndrome type I (OFD1) is usually male lethal during gestation and predominantly affects females. OFD1 is characterized by the following: oral features (lobulated tongue, tongue nodules, cleft of the hard or soft palate, accessory gingival frenulae, hypodontia, and other dental abnormalities); facial features (widely spaced eyes, telecanthus, hypoplasia of the alae nasi, median cleft or pseudocleft of the upper lip, micrognathia); digital features (brachydactyly, syndactyly, clinodactyly of the fifth finger, duplicated great toe); polycystic kidney disease; brain MRI findings (intracerebral cysts, agenesis of the corpus callosum, cerebellar agenesis with or without Dandy-Walker malformation); and intellectual disability (in approximately 50% of affected individuals).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/307142">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_341455"><div><strong>Saldino-Mainzer syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>341455</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1849437</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Short-rib thoracic dysplasia (SRTD) with or without polydactyly refers to a group of autosomal recessive skeletal ciliopathies that are characterized by a constricted thoracic cage, short ribs, shortened tubular bones, and a 'trident' appearance of the acetabular roof. SRTD encompasses Ellis-van Creveld syndrome (EVC) and the disorders previously designated as Jeune syndrome or asphyxiating thoracic dystrophy (ATD), short rib-polydactyly syndrome (SRPS), and Mainzer-Saldino syndrome (MZSDS). Polydactyly is variably present, and there is phenotypic overlap in the various forms of SRTDs, which differ by visceral malformation and metaphyseal appearance. Nonskeletal involvement can include cleft lip/palate as well as anomalies of major organs such as the brain, eye, heart, kidneys, liver, pancreas, intestines, and genitalia. Some forms of SRTD are lethal in the neonatal period due to respiratory insufficiency secondary to a severely restricted thoracic cage, whereas others are compatible with life (summary by Huber and Cormier-Daire, 2012 and Schmidts et al., 2013).&#13; There is phenotypic overlap with the cranioectodermal dysplasias (Sensenbrenner syndrome; see CED1, 218330).&#13; For a discussion of genetic heterogeneity of short-rib thoracic dysplasia, see SRTD1 (208500).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/341455">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_347541"><div><strong>Neonatal diabetes mellitus with congenital hypothyroidism</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>347541</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1857775</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Neonatal diabetes mellitus with congenital hypothyroidism (NDH) syndrome is characterized by intrauterine growth retardation and onset of nonimmune diabetes mellitus within the first few weeks of life. Other features include renal parenchymal disease, primarily renal cystic dysplasia, and hepatic disease, with hepatitis in some patients and hepatic fibrosis and cirrhosis in others. Facial dysmorphism, when present, consistently involves low-set ears, epicanthal folds, flat nasal bridge, long philtrum, and thin upper lip. Most patients exhibit developmental delay (Dimitri et al., 2015).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/347541">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_347864"><div><strong>Campomelia, Cumming type</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>347864</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1859371</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">The association of limb defects and multivisceral anomalies. The syndrome has been reported in eight infants from four different families. Skeletal features include tetramelic campomelia and short long bones. Extraskeletal manifestations may include cervical lymphocele, generalised hydrops, polycystic kidneys, pancreas and liver, fibrotic liver or pancreas, polysplenia, heterotaxia, hypoplastic lung, short bowel. All newborns reported so far were either stillborn or died shortly after birth.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/347864">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_382217"><div><strong>NPHP3-related Meckel-like syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>382217</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C2673885</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">This autosomal recessive disorder is designated Meckel syndrome type 7 (MKS7) based on the classic phenotypic triad of (1) cystic renal disease; (2) a central nervous system abnormality, and (3) hepatic abnormalities, as defined by Meckel (1822), Salonen (1984), and Logan et al. (2011). According to these criteria, polydactyly is a variable feature.&#13; Herriot et al. (1991) and Al-Gazali et al. (1996) concluded that Dandy-Walker malformation can be the phenotypic manifestation of a central nervous system malformation in MKS.&#13; For a general phenotypic description and a discussion of genetic heterogeneity of Meckel syndrome, see MKS1 (249000).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/382217">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_461769"><div><strong>Nephronophthisis-like nephropathy 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>461769</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C3150419</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Nephronophthisis-like nephropathy-1 (NPHPL1) is an autosomal recessive cystic kidney disease characterized by the onset of progressive renal insufficiency in childhood. End-stage renal disease occurs in the first 3 decades of life. The disorder may be associated with extrarenal manifestations, including hepatic and central nervous system involvement (summary by O'Toole et al., 2010).&#13; For a general phenotypic description and a discussion of genetic heterogeneity of nephronophthisis, see NPHP1 (256100).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/461769">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_482242"><div><strong>Nephronophthisis 13</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>482242</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C3280612</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">A nephronophthisis that has material basis in homozygous or compound heterozygous mutation in the WDR19 gene on chromosome 4p14.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/482242">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_811626"><div><strong>Renal-hepatic-pancreatic dysplasia 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>811626</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C3715199</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Any renal-hepatic-pancreatic dysplasia in which the cause of the disease is a mutation in the NPHP3 gene.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/811626">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_905171"><div><strong>Senior-Loken syndrome 8</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>905171</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C4225376</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Any Senior-Loken syndrome in which the cause of the disease is a mutation in the WDR19 gene.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/905171">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1621793"><div><strong>Polycystic kidney disease 4</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1621793</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C4540575</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Autosomal recessive polycystic kidney disease PKHD1 (ARPKD-PKHD1) is characterized by primary involvement of the kidneys and liver with mostly secondary effects seen in other organ systems. Of the three ages of initial presentation of kidney disease, the two most common are perinatal (i.e., prenatal/neonatal) and infantile (four weeks to age one year) with the classic finding of enlarged kidneys. The major difference between the perinatal and infantile presentations, which typically have similar kidney and liver findings, is the frequent occurrence of pulmonary involvement in the perinatal presentation, which is a major cause of morbidity and mortality in neonates. The less common initial presentation in childhood (after age one year) to young adulthood can be associated with predominant hepatobiliary manifestations characterized by the clinical consequences of developmental anomalies of biliary ductal plate remodeling (also known as Caroli disease). Although the short-term and long-term mortality rates of ARPKD remain significant, the survival of individuals with ARPKD has improved with modern neonatal respiratory support, kidney replacement therapy (KRT) including dialysis and kidney transplantation (KTx), and liver transplantation (LTx) or combined liver and kidney transplantation (CLKTx).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1621793">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1648057"><div><strong>Asphyxiating thoracic dystrophy 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1648057</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C4551856</a></dd><dt><span class="dotprefix"></span></dt><dd>Congenital Abnormality</dd></dl></div></div></div>
<div class="spaceAbove">Short-rib thoracic dysplasia (SRTD) with or without polydactyly refers to a group of autosomal recessive skeletal ciliopathies that are characterized by a constricted thoracic cage, short ribs, shortened tubular bones, and a 'trident' appearance of the acetabular roof. SRTD encompasses Ellis-van Creveld syndrome (EVC) and the disorders previously designated as Jeune syndrome or asphyxiating thoracic dystrophy (ATD), short rib-polydactyly syndrome (SRPS), and Mainzer-Saldino syndrome (MZSDS). Polydactyly is variably present, and there is phenotypic overlap in the various forms of SRTDs, which differ by visceral malformation and metaphyseal appearance. Nonskeletal involvement can include cleft lip/palate as well as anomalies of major organs such as the brain, eye, heart, kidneys, liver, pancreas, intestines, and genitalia. Some forms of SRTD are lethal in the neonatal period due to respiratory insufficiency secondary to a severely restricted thoracic cage, whereas others are compatible with life (summary by Huber and Cormier-Daire, 2012 and Schmidts et al., 2013).&#13; There is phenotypic overlap with the cranioectodermal dysplasias (Sensenbrenner syndrome; see CED1, 218330).&#13; Genetic Heterogeneity of Asphyxiating Thoracic Dysplasia&#13; SRTD1 has been mapped to chromosome 15q13. See also SRTD2 (611263), caused by mutation in the IFT80 gene (611177); SRTD3 (613091), caused by mutation in the DYNC2H1 gene (603297); SRTD4 (613819), caused by mutation in the TTC21B gene (612014); SRTD5 (614376), caused by mutation in the WDR19 gene (608151); SRTD6 (263520), caused by mutation in the NEK1 gene (604588); SRTD7 (614091), caused by mutation in the WDR35 gene (613602); SRTD8 (615503), caused by mutation in the WDR60 gene (615462); SRTD9 (266920), caused by mutation in the IFT140 gene (614620); SRTD10 (615630), caused by mutation in the IFT172 gene (607386); SRTD11 (615633), caused by mutation in the WDR34 gene (613363); SRTD13 (616300), caused by mutation in the CEP120 gene (613446); SRTD14 (616546), caused by mutation in the KIAA0586 gene (610178); SRTD15 (617088), caused by mutation in the DYNC2LI1 gene (617083); SRTD16 (617102), caused by mutation in the IFT52 gene (617094); SRTD17 (617405), caused by mutation in the TCTEX1D2 gene (617353); SRTD18 (617866), caused by mutation in the IFT43 gene (614068); SRTD19 (617895), caused by mutation in the IFT81 gene (605489); SRTD20 (617925), caused by mutation in the INTU gene (610621); and SRTD21 (619479), caused by mutation in the KIAA0753 gene (617112).&#13; See also SRTD12 (Beemer-Langer syndrome; 269860).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1648057">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1840225"><div><strong>Intellectual developmental disorder, X-linked 112</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1840225</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C5829589</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">X-linked intellectual disorder-112 (XLID112) is a neurodevelopmental disorder characterized by developmental delay, with speech delay more prominent than motor delay, autism or autism traits, and variable dysmorphic features. Affected females have been reported, which appears to be related to skewed X-inactivation (summary by Hiatt et al., 2023).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1840225">Condition Record</a></div></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1648057" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Asphyxiating thoracic dystrophy 1</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_347864" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Campomelia, Cumming type</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1840225" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Intellectual developmental disorder, X-linked 112</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_347541" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Neonatal diabetes mellitus with congenital hypothyroidism</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_482242" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Nephronophthisis 13</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (14)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_461769" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Nephronophthisis-like nephropathy 1</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_382217" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">NPHP3-related Meckel-like syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_307142" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Orofaciodigital syndrome I</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1621793" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Polycystic kidney disease 4</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_61235" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Radial aplasia-thrombocytopenia syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_811626" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Renal-hepatic-pancreatic dysplasia 1</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_341455" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Saldino-Mainzer syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_905171" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Senior-Loken syndrome 8</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_42458" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Von Hippel-Lindau syndrome</a></div></span></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/38442782">Diagnosis and Management of Pancreatic Cysts.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gardner TB,
Park WG,
Allen PJ</span><br />
<span class="medgenPMjournal">Gastroenterology</span>
2024 Aug;167(3):454-468.
Epub 2024 Mar 3
doi: 10.1053/j.gastro.2024.02.041.
<span class="bold">PMID: </span><a href="/pubmed/38442782" target="_blank">38442782</a></div>
<div class="nl"><a target="_blank" href="/pubmed/38182527">International evidence-based Kyoto guidelines for the management of intraductal papillary mucinous neoplasm of the pancreas.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ohtsuka T,
Fernandez-Del Castillo C,
Furukawa T,
Hijioka S,
Jang JY,
Lennon AM,
Miyasaka Y,
Ohno E,
Salvia R,
Wolfgang CL,
Wood LD</span><br />
<span class="medgenPMjournal">Pancreatology</span>
2024 Mar;24(2):255-270.
Epub 2023 Dec 28
doi: 10.1016/j.pan.2023.12.009.
<span class="bold">PMID: </span><a href="/pubmed/38182527" target="_blank">38182527</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29485131">ACG Clinical Guideline: Diagnosis and Management of Pancreatic Cysts.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Elta GH,
Enestvedt BK,
Sauer BG,
Lennon AM</span><br />
<span class="medgenPMjournal">Am J Gastroenterol</span>
2018 Apr;113(4):464-479.
Epub 2018 Feb 27
doi: 10.1038/ajg.2018.14.
<span class="bold">PMID: </span><a href="/pubmed/29485131" target="_blank">29485131</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22pancreatic%20cysts%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (105)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/38442782">Diagnosis and Management of Pancreatic Cysts.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gardner TB,
Park WG,
Allen PJ</span><br />
<span class="medgenPMjournal">Gastroenterology</span>
2024 Aug;167(3):454-468.
Epub 2024 Mar 3
doi: 10.1053/j.gastro.2024.02.041.
<span class="bold">PMID: </span><a href="/pubmed/38442782" target="_blank">38442782</a></div>
<div class="nl"><a target="_blank" href="/pubmed/38182527">International evidence-based Kyoto guidelines for the management of intraductal papillary mucinous neoplasm of the pancreas.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ohtsuka T,
Fernandez-Del Castillo C,
Furukawa T,
Hijioka S,
Jang JY,
Lennon AM,
Miyasaka Y,
Ohno E,
Salvia R,
Wolfgang CL,
Wood LD</span><br />
<span class="medgenPMjournal">Pancreatology</span>
2024 Mar;24(2):255-270.
Epub 2023 Dec 28
doi: 10.1016/j.pan.2023.12.009.
<span class="bold">PMID: </span><a href="/pubmed/38182527" target="_blank">38182527</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37245933">Pancreatic Cysts: Radiology.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Megibow AJ</span><br />
<span class="medgenPMjournal">Gastrointest Endosc Clin N Am</span>
2023 Jul;33(3):519-531.
Epub 2023 Apr 24
doi: 10.1016/j.giec.2023.03.008.
<span class="bold">PMID: </span><a href="/pubmed/37245933" target="_blank">37245933</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36153109">Pancreatic Cystic Neoplasms.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Coban S,
Basar O,
Brugge WR</span><br />
<span class="medgenPMjournal">Gastroenterol Clin North Am</span>
2022 Sep;51(3):537-559.
Epub 2022 Aug 30
doi: 10.1016/j.gtc.2022.06.008.
<span class="bold">PMID: </span><a href="/pubmed/36153109" target="_blank">36153109</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29485131">ACG Clinical Guideline: Diagnosis and Management of Pancreatic Cysts.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Elta GH,
Enestvedt BK,
Sauer BG,
Lennon AM</span><br />
<span class="medgenPMjournal">Am J Gastroenterol</span>
2018 Apr;113(4):464-479.
Epub 2018 Feb 27
doi: 10.1038/ajg.2018.14.
<span class="bold">PMID: </span><a href="/pubmed/29485131" target="_blank">29485131</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Pancreatic%20cysts%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (550)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/39231345">Pancreatic Cysts.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gonda TA,
Cahen DL,
Farrell JJ</span><br />
<span class="medgenPMjournal">N Engl J Med</span>
2024 Sep 5;391(9):832-843.
doi: 10.1056/NEJMra2309041.
<span class="bold">PMID: </span><a href="/pubmed/39231345" target="_blank">39231345</a></div>
<div class="nl"><a target="_blank" href="/pubmed/38442782">Diagnosis and Management of Pancreatic Cysts.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gardner TB,
Park WG,
Allen PJ</span><br />
<span class="medgenPMjournal">Gastroenterology</span>
2024 Aug;167(3):454-468.
Epub 2024 Mar 3
doi: 10.1053/j.gastro.2024.02.041.
<span class="bold">PMID: </span><a href="/pubmed/38442782" target="_blank">38442782</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36153109">Pancreatic Cystic Neoplasms.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Coban S,
Basar O,
Brugge WR</span><br />
<span class="medgenPMjournal">Gastroenterol Clin North Am</span>
2022 Sep;51(3):537-559.
Epub 2022 Aug 30
doi: 10.1016/j.gtc.2022.06.008.
<span class="bold">PMID: </span><a href="/pubmed/36153109" target="_blank">36153109</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34629795">Updates in diagnosis and management of pancreatic cysts.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Lee LS</span><br />
<span class="medgenPMjournal">World J Gastroenterol</span>
2021 Sep 14;27(34):5700-5714.
doi: 10.3748/wjg.v27.i34.5700.
<span class="bold">PMID: </span><a href="/pubmed/34629795" target="_blank">34629795</a><a href="/pmc/articles/PMC8473602" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29485131">ACG Clinical Guideline: Diagnosis and Management of Pancreatic Cysts.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Elta GH,
Enestvedt BK,
Sauer BG,
Lennon AM</span><br />
<span class="medgenPMjournal">Am J Gastroenterol</span>
2018 Apr;113(4):464-479.
Epub 2018 Feb 27
doi: 10.1038/ajg.2018.14.
<span class="bold">PMID: </span><a href="/pubmed/29485131" target="_blank">29485131</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Pancreatic%20cysts%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (739)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/37847503">Long-Term Outcomes and Risk of Pancreatic Cancer in Intraductal Papillary Mucinous Neoplasms.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">de la Fuente J,
Chatterjee A,
Lui J,
Nehra AK,
Bell MG,
Lennon RJ,
Kassmeyer BA,
Graham RP,
Nagayama H,
Schulte PJ,
Doering KA,
Delgado AM,
Vege SS,
Chari ST,
Takahashi N,
Majumder S</span><br />
<span class="medgenPMjournal">JAMA Netw Open</span>
2023 Oct 2;6(10):e2337799.
doi: 10.1001/jamanetworkopen.2023.37799.
<span class="bold">PMID: </span><a href="/pubmed/37847503" target="_blank">37847503</a><a href="/pmc/articles/PMC10582793" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33333055">Lead-Time Trajectory of CA19-9 as an Anchor Marker for Pancreatic Cancer Early Detection.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Fahrmann JF,
Schmidt CM,
Mao X,
Irajizad E,
Loftus M,
Zhang J,
Patel N,
Vykoukal J,
Dennison JB,
Long JP,
Do KA,
Zhang J,
Chabot JA,
Kluger MD,
Kastrinos F,
Brais L,
Babic A,
Jajoo K,
Lee LS,
Clancy TE,
Ng K,
Bullock A,
Genkinger J,
Yip-Schneider MT,
Maitra A,
Wolpin BM,
Hanash S</span><br />
<span class="medgenPMjournal">Gastroenterology</span>
2021 Mar;160(4):1373-1383.e6.
Epub 2020 Dec 14
doi: 10.1053/j.gastro.2020.11.052.
<span class="bold">PMID: </span><a href="/pubmed/33333055" target="_blank">33333055</a><a href="/pmc/articles/PMC8783758" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31016391">EUS-Guided Pancreatic Cyst Ablation: a Clinical and Technical Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Moyer MT,
Maranki JL,
DeWitt JM</span><br />
<span class="medgenPMjournal">Curr Gastroenterol Rep</span>
2019 Apr 23;21(5):19.
doi: 10.1007/s11894-019-0686-5.
<span class="bold">PMID: </span><a href="/pubmed/31016391" target="_blank">31016391</a><a href="/pmc/articles/PMC11613143" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/26076909">Digestive Disease Week (DDW) 2015: Pancreaticobiliary update.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Varadarajulu S,
Bang JY</span><br />
<span class="medgenPMjournal">Dig Endosc</span>
2015 Sep;27(6):657-61.
Epub 2015 Jul 15
doi: 10.1111/den.12504.
<span class="bold">PMID: </span><a href="/pubmed/26076909" target="_blank">26076909</a></div>
<div class="nl"><a target="_blank" href="/pubmed/20651590">Pancreatic surgery.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Donahue TR,
Reber HA</span><br />
<span class="medgenPMjournal">Curr Opin Gastroenterol</span>
2010 Sep;26(5):499-505.
doi: 10.1097/MOG.0b013e32833d1174.
<span class="bold">PMID: </span><a href="/pubmed/20651590" target="_blank">20651590</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Pancreatic%20cysts%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (90)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/38442782">Diagnosis and Management of Pancreatic Cysts.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gardner TB,
Park WG,
Allen PJ</span><br />
<span class="medgenPMjournal">Gastroenterology</span>
2024 Aug;167(3):454-468.
Epub 2024 Mar 3
doi: 10.1053/j.gastro.2024.02.041.
<span class="bold">PMID: </span><a href="/pubmed/38442782" target="_blank">38442782</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30721664">Early Detection of Pancreatic Cancer: Opportunities and Challenges.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Singhi AD,
Koay EJ,
Chari ST,
Maitra A</span><br />
<span class="medgenPMjournal">Gastroenterology</span>
2019 May;156(7):2024-2040.
Epub 2019 Feb 2
doi: 10.1053/j.gastro.2019.01.259.
<span class="bold">PMID: </span><a href="/pubmed/30721664" target="_blank">30721664</a><a href="/pmc/articles/PMC6486851" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28609359">Pancreatic Cysts: Controversies, Advances, Diagnoses, and Therapies.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Barkin JA,
Barkin JS</span><br />
<span class="medgenPMjournal">Pancreas</span>
2017 Jul;46(6):735-741.
doi: 10.1097/MPA.0000000000000831.
<span class="bold">PMID: </span><a href="/pubmed/28609359" target="_blank">28609359</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28404111">Global incidence and mortality of pancreatic diseases: a systematic review, meta-analysis, and meta-regression of population-based cohort studies.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Xiao AY,
Tan ML,
Wu LM,
Asrani VM,
Windsor JA,
Yadav D,
Petrov MS</span><br />
<span class="medgenPMjournal">Lancet Gastroenterol Hepatol</span>
2016 Sep;1(1):45-55.
Epub 2016 Jun 28
doi: 10.1016/S2468-1253(16)30004-8.
<span class="bold">PMID: </span><a href="/pubmed/28404111" target="_blank">28404111</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27013369">Therapeutic Approach to Cystic Neoplasms of the Pancreas.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Al Efishat M,
Allen PJ</span><br />
<span class="medgenPMjournal">Surg Oncol Clin N Am</span>
2016 Apr;25(2):351-61.
doi: 10.1016/j.soc.2015.11.006.
<span class="bold">PMID: </span><a href="/pubmed/27013369" target="_blank">27013369</a><a href="/pmc/articles/PMC4991876" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Pancreatic%20cysts%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (329)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/38442782">Diagnosis and Management of Pancreatic Cysts.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gardner TB,
Park WG,
Allen PJ</span><br />
<span class="medgenPMjournal">Gastroenterology</span>
2024 Aug;167(3):454-468.
Epub 2024 Mar 3
doi: 10.1053/j.gastro.2024.02.041.
<span class="bold">PMID: </span><a href="/pubmed/38442782" target="_blank">38442782</a></div>
<div class="nl"><a target="_blank" href="/pubmed/38182527">International evidence-based Kyoto guidelines for the management of intraductal papillary mucinous neoplasm of the pancreas.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ohtsuka T,
Fernandez-Del Castillo C,
Furukawa T,
Hijioka S,
Jang JY,
Lennon AM,
Miyasaka Y,
Ohno E,
Salvia R,
Wolfgang CL,
Wood LD</span><br />
<span class="medgenPMjournal">Pancreatology</span>
2024 Mar;24(2):255-270.
Epub 2023 Dec 28
doi: 10.1016/j.pan.2023.12.009.
<span class="bold">PMID: </span><a href="/pubmed/38182527" target="_blank">38182527</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35731507">Comparison of Society Guidelines for the Management and Surveillance of Pancreatic Cysts: A Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Aziz H,
Acher AW,
Krishna SG,
Cloyd JM,
Pawlik TM</span><br />
<span class="medgenPMjournal">JAMA Surg</span>
2022 Aug 1;157(8):723-730.
doi: 10.1001/jamasurg.2022.2232.
<span class="bold">PMID: </span><a href="/pubmed/35731507" target="_blank">35731507</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30721664">Early Detection of Pancreatic Cancer: Opportunities and Challenges.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Singhi AD,
Koay EJ,
Chari ST,
Maitra A</span><br />
<span class="medgenPMjournal">Gastroenterology</span>
2019 May;156(7):2024-2040.
Epub 2019 Feb 2
doi: 10.1053/j.gastro.2019.01.259.
<span class="bold">PMID: </span><a href="/pubmed/30721664" target="_blank">30721664</a><a href="/pmc/articles/PMC6486851" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27013369">Therapeutic Approach to Cystic Neoplasms of the Pancreas.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Al Efishat M,
Allen PJ</span><br />
<span class="medgenPMjournal">Surg Oncol Clin N Am</span>
2016 Apr;25(2):351-61.
doi: 10.1016/j.soc.2015.11.006.
<span class="bold">PMID: </span><a href="/pubmed/27013369" target="_blank">27013369</a><a href="/pmc/articles/PMC4991876" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Pancreatic%20cysts%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (316)</a></div></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="nl"><a target="_blank" href="/pubmed/37230894">Predictive ability of pancreatic cyst fluid biomarkers: A systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Pflüger MJ,
Jamouss KT,
Afghani E,
Lim SJ,
Rodriguez Franco S,
Mayo H,
Spann M,
Wang H,
Singhi A,
Lennon AM,
Wood LD</span><br />
<span class="medgenPMjournal">Pancreatology</span>
2023 Nov;23(7):868-877.
Epub 2023 May 15
doi: 10.1016/j.pan.2023.05.005.
<span class="bold">PMID: </span><a href="/pubmed/37230894" target="_blank">37230894</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35912889">Antibioprophylaxis in endoscopic ultrasound guided fine needle aspiration in pancreatic cysts: A systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Khoury T,
Gincul R,
Mohammedi I,
Sbeit W,
Napoléon B</span><br />
<span class="medgenPMjournal">J Gastroenterol Hepatol</span>
2022 Sep;37(9):1685-1692.
Epub 2022 Aug 5
doi: 10.1111/jgh.15972.
<span class="bold">PMID: </span><a href="/pubmed/35912889" target="_blank">35912889</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33731599">Intracystic Glucose Levels in Differentiating Mucinous From Nonmucinous Pancreatic Cysts: A Systematic Review and Meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Mohan BP,
Madhu D,
Khan SR,
Kassab LL,
Ponnada S,
Chandan S,
Facciorusso A,
Crino SF,
Barresi L,
McDonough S,
Adler DG</span><br />
<span class="medgenPMjournal">J Clin Gastroenterol</span>
2022 Feb 1;56(2):e131-e136.
doi: 10.1097/MCG.0000000000001507.
<span class="bold">PMID: </span><a href="/pubmed/33731599" target="_blank">33731599</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31341368">Genetic testing vs microforceps biopsy in pancreatic cysts: Systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Faias S,
Pereira L,
Luís Â,
Chaves P,
Cravo M</span><br />
<span class="medgenPMjournal">World J Gastroenterol</span>
2019 Jul 14;25(26):3450-3467.
doi: 10.3748/wjg.v25.i26.3450.
<span class="bold">PMID: </span><a href="/pubmed/31341368" target="_blank">31341368</a><a href="/pmc/articles/PMC6639554" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28404111">Global incidence and mortality of pancreatic diseases: a systematic review, meta-analysis, and meta-regression of population-based cohort studies.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Xiao AY,
Tan ML,
Wu LM,
Asrani VM,
Windsor JA,
Yadav D,
Petrov MS</span><br />
<span class="medgenPMjournal">Lancet Gastroenterol Hepatol</span>
2016 Sep;1(1):45-55.
Epub 2016 Jun 28
doi: 10.1016/S2468-1253(16)30004-8.
<span class="bold">PMID: </span><a href="/pubmed/28404111" target="_blank">28404111</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Pancreatic%20cysts%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (20)</a></div></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22pancreatic%20cysts%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Pancreatic%20cysts%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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