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<!--
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||
UID=44564
|
||
ConceptID=C0027121
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Myositis disease</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>44564</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0027121</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Myositis</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Muscle inflammation (26889001); Inflammatory disorder of muscle (26889001); Inflammatory myopathy (26889001); Myositis (26889001)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0100614">HP:0100614</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0021167" target="_blank">MONDO:0021167</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/160750" target="_blank">160750</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Idiopathic inflammatory myopathy is a group of disorders characterized by inflammation of the muscles used for movement (skeletal muscles). Idiopathic inflammatory myopathy usually appears in adults between ages 40 and 60 or in children between ages 5 and 15, though it can occur at any age.<br /><br />In sporadic inclusion body myositis, the muscles most affected are those of the wrists and fingers and the front of the thigh. Affected individuals may frequently stumble while walking and find it difficult to grasp items. As in dermatomyositis and polymyositis, swallowing can be difficult.<br /><br />The primary symptom of idiopathic inflammatory myopathy is muscle weakness, which develops gradually over a period of weeks to months or even years. Other symptoms include joint pain and general tiredness (fatigue).<br /><br />There are several forms of idiopathic inflammatory myopathy, including polymyositis, dermatomyositis, and sporadic inclusion body myositis.<br /><br />Polymyositis and dermatomyositis involve weakness of the muscles closest to the center of the body (proximal muscles), such as the muscles of the hips and thighs, upper arms, and neck. People with these forms of idiopathic inflammatory myopathy may find it difficult to climb stairs, get up from a seated position, or lift items above their head. In some cases, muscle weakness may make swallowing or breathing difficult.<br /><br />Polymyositis and dermatomyositis have similar symptoms, but dermatomyositis is distinguished by a reddish or purplish rash on the eyelids, elbows, knees, or knuckles. Sometimes, abnormal calcium deposits form hard, painful bumps under the skin (calcinosis). [from <a title="MedlinePlus Genetics" href="https://medlineplus.gov/genetics/" class="defSource" target="_blank">MedlinePlus Genetics</a>]</div>
|
||
</div>
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||
|
||
<div class="portlet mgSection" id="ID_118">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0027121[DISCUI]&test_type=Clinical" ref="ncbi_uid=44564">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=44564" target="_blank" href="/omim/160750">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Myositis disease</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/867388" ref="tree=MeSH" title="MedGen record for Abnormality of the immune system">Abnormality of the immune system</a></span><ul><li><span class="TLline"><a href="/medgen/869194" ref="tree=MeSH" title="MedGen record for Abnormality of immune system physiology">Abnormality of immune system physiology</a></span><ul><li><span class="TLline"><a href="/medgen/868411" ref="tree=MeSH" title="MedGen record for Abnormal inflammatory response">Abnormal inflammatory response</a></span><ul><li><span class="TLline"><a href="/medgen/868409" ref="tree=MeSH" title="MedGen record for Increased inflammatory response">Increased inflammatory response</a></span><ul><li><span class="matched_ds">Myositis disease</span><ul><li><span class="TLline"><a href="/medgen/235204" ref="tree=MeSH" title="MedGen record for Idiopathic granulomatous myositis">Idiopathic granulomatous myositis</a></span></li><li><span class="TLline"><a href="/medgen/68659" ref="tree=MeSH" title="MedGen record for Inclusion body myositis">Inclusion body myositis</a></span></li><li><span class="TLline"><a href="/medgen/102358" ref="tree=MeSH" title="MedGen record for Infectious myositis">Infectious myositis</a></span></li><li><span class="TLline"><a href="/medgen/57855" ref="tree=MeSH" title="MedGen record for Myositis fibrosa">Myositis fibrosa</a></span></li><li><span class="TLline"><a href="/medgen/6503" ref="tree=MeSH" title="MedGen record for Myositis ossificans">Myositis ossificans</a></span></li><li><span class="TLline"><a href="/medgen/389999" ref="tree=MeSH" title="MedGen record for Orbital myositis">Orbital myositis</a></span></li><li><span class="TLline"><a href="/medgen/39086" ref="tree=MeSH" title="MedGen record for Polymyositis">Polymyositis</a></span><ul><li><span class="TLline"><a href="/medgen/8331" ref="tree=MeSH" title="MedGen record for Dermatomyositis">Dermatomyositis</a></span><ul><li><span class="TLline"><a href="/medgen/66356" ref="tree=MeSH" title="MedGen record for Adult dermatomyositis">Adult dermatomyositis</a></span></li><li><span class="TLline"><a href="/medgen/120486" ref="tree=MeSH" title="MedGen record for Childhood type dermatomyositis">Childhood type dermatomyositis</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/819736" ref="tree=MeSH" title="MedGen record for Juvenile polymyositis">Juvenile polymyositis</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/52862" ref="tree=MeSH" title="MedGen record for Pyomyositis">Pyomyositis</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_226899"><div><strong>TNF receptor-associated periodic fever syndrome (TRAPS)</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>226899</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1275126</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">TNF receptor-associated periodic fever syndrome (TRAPS) is characterized by episodes of inflammation typically occurring every four to six weeks and lasting between five and 25 days. Flares may be prompted by stress, infection, trauma, hormonal changes, and vaccination. Symptoms may include fever, abdominal pain, arthralgia, myalgia, migratory rash, and eye inflammation, with variable severity. Symptoms often begin in early childhood (median age 4.3 years), though symptom onset can occur later in life. During a flare, acute-phase reactants such as C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and serum amyloid A are typically elevated. Generally, acute-phase reactants stabilize between flares but may remain somewhat elevated even in the absence of clinical symptoms. AA amyloidosis, the most severe sequela of TRAPS, can largely be avoided with adequate treatment. Proteinuria and kidney failure occur in 80%-90% of affected individuals with amyloidosis, while intestinal, thyroid, myocardium, liver, and spleen deposits are less common.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/226899">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_358391"><div><strong>Autosomal recessive limb-girdle muscular dystrophy type 2A</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>358391</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1869123</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Calpainopathy is characterized by symmetric and progressive weakness of proximal limb-girdle muscles. Clinical findings of calpainopathy include the tendency to walk on tiptoe, difficulty in running, scapular winging, waddling gait, laxity of the abdominal muscles, Achilles tendon shortening, and scoliosis. Affected individuals typically do not have cardiac involvement or intellectual disability. Three autosomal recessive calpainopathy phenotypes have been identified based on the distribution of muscle weakness and age at onset: Pelvifemoral limb-girdle muscular dystrophy (LGMD) (Leyden-Möbius LGMD) phenotype, the most frequently observed calpainopathy phenotype, in which muscle weakness is first evident in the pelvic girdle and later in the shoulder girdle, with onset that may occur as early as before age 12 years or as late as after age 30 years. Scapulohumeral LGMD (Erb LGMD) phenotype, usually a milder phenotype with infrequent early onset, in which muscle weakness is first evident in the shoulder girdle and later in the pelvic girdle. HyperCKemia, usually observed in children or young individuals, in which individuals are asymptomatic and have high serum creatine kinase (CK) concentrations. The autosomal dominant form of calpainopathy is clinically variable, ranging from almost asymptomatic to wheelchair dependence after age 60 years in a few individuals; phenotype is generally milder than the recessive form.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/358391">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_815798"><div><strong>Inclusion body myopathy with early-onset Paget disease with or without frontotemporal dementia 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>815798</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3809468</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Inclusion body myopathy associated with Paget disease of bone (PDB) and/or frontotemporal dementia (IBMPFD) is characterized by adult-onset proximal and distal muscle weakness (clinically resembling a limb-girdle muscular dystrophy syndrome), early-onset PDB, and premature frontotemporal dementia (FTD). Muscle weakness progresses to involve other limb and respiratory muscles. PDB involves focal areas of increased bone turnover that typically lead to spine and/or hip pain and localized enlargement and deformity of the long bones; pathologic fractures occur on occasion. Early stages of FTD are characterized by dysnomia, dyscalculia, comprehension deficits, and paraphasic errors, with minimal impairment of episodic memory; later stages are characterized by inability to speak, auditory comprehension deficits for even one-step commands, alexia, and agraphia. Mean age at diagnosis for muscle disease and PDB is 42 years; for FTD, 56 years. Dilated cardiomyopathy, amyotrophic lateral sclerosis, and Parkinson disease are now known to be part of the spectrum of findings associated with IBMPFD.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/815798">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_854861"><div><strong>Familial idiopathic inflammatory myopathy</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>854861</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3888318</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">An instance of myositis that is caused by an inherited genomic modification in an individual, and has an unknown cause.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/854861">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_863159"><div><strong>STING-associated vasculopathy with onset in infancy</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>863159</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4014722</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">STING-associated vasculopathy with onset in infancy is an autoinflammatory vasculopathy causing severe skin lesions, particularly affecting the face, ears, nose, and digits, and resulting in ulceration, eschar formation, necrosis, and, in some cases, amputation. Many patients have interstitial lung disease. Tissue biopsy and laboratory findings show a hyperinflammatory state, with evidence of increased beta-interferon (IFNB1; 147640) signaling (summary by Liu et al., 2014).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/863159">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1648456"><div><strong>Proteasome-associated autoinflammatory syndrome 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1648456</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4747850</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Proteasome-associated autoinflammatory syndrome-3 (PRAAS3) is an autosomal recessive syndrome with onset in early infancy. Affected individuals present with nodular dermatitis, recurrent fever, myositis, panniculitis-induced lipodystrophy, lymphadenopathy, and dysregulation of the immune response, particularly associated with abnormal type I interferon-induced gene expression patterns. Additional features are highly variable, but may include joint contractures, hepatosplenomegaly, anemia, thrombocytopenia, recurrent infections, autoantibodies, and hypergammaglobulinemia. Some patients may have intracranial calcifications (summary by Brehm et al., 2015). For a discussion of genetic heterogeneity of PRAAS, see PRAAS1 (256040).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1648456">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1780127"><div><strong>Proteasome-associated autoinflammatory syndrome 4</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1780127</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5543053</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Proteasome-associated autoinflammatory syndrome-4 (PRAAS4) is an autosomal recessive immunologic disorder characterized by onset of panniculitis and erythematous skin lesions in early infancy. Additional features include hepatosplenomegaly, lymphadenopathy, fever, generalized lipodystrophy, myositis, and joint contractures, as well as delayed motor and speech development. Autoimmune features, such as hemolytic anemia, may also occur. Laboratory studies show elevation of acute phase reactants and abnormal activation of the type I interferon response. Treatment with the JAK (see 147795) inhibitor ruxolitinib may result in clinical improvement (summary by de Jesus et al., 2019). For a discussion of genetic heterogeneity of PRAAS, see PRAAS1 (256040).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1780127">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1851770"><div><strong>Immunodeficiency 113 with autoimmunity and autoinflammation</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1851770</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5882711</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Immunodeficiency-113 with autoimmunity and autoinflammation (IMD113) is an autosomal recessive complex immunologic disorder with onset of symptoms in infancy. Affected individuals have recurrent infections and usually show features of autoimmunity and autoinflammation, such as hemolytic anemia, thrombocytopenia, hepatosplenomegaly, leukocytosis, neutrophilia, and elevated acute phase reactants. More variable systemic features may include celiac disease or enteropathy, ileus, nephropathy, eczema, and dermatomyositis. Additional features include facial dysmorphism, scoliosis, and poor wound healing. One patient with neurodevelopmental abnormalities has been reported. The disorder results from dysregulation of the actin cytoskeleton that affects certain cell lineages (Nunes-Santos et al., 2023).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1851770">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1857440"><div><strong>Proteasome-associated autoinflammatory syndrome 6</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1857440</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5935614</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Proteasome-associated autoinflammatory syndrome-6 (PRAAS6) is characterized by a proteasome-associated autoinflammatory syndrome with immunodeficiency (Kanazawa et al., 2021).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1857440">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_358391" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Autosomal recessive limb-girdle muscular dystrophy type 2A</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_854861" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial idiopathic inflammatory myopathy</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1851770" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Immunodeficiency 113 with autoimmunity and autoinflammation</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_815798" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Inclusion body myopathy with early-onset Paget disease with or without frontotemporal dementia 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1648456" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Proteasome-associated autoinflammatory syndrome 3</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (9)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1780127" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Proteasome-associated autoinflammatory syndrome 4</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1857440" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Proteasome-associated autoinflammatory syndrome 6</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_863159" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">STING-associated vasculopathy with onset in infancy</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_226899" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">TNF receptor-associated periodic fever syndrome (TRAPS)</a></div></span></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/32284267">Clinical manifestations and treatment of antisynthetase syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Marco JL,
|
||
Collins BF</span><br />
|
||
<span class="medgenPMjournal">Best Pract Res Clin Rheumatol</span>
|
||
2020 Aug;34(4):101503.
|
||
Epub 2020 Apr 11
|
||
doi: 10.1016/j.berh.2020.101503.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32284267" target="_blank">32284267</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30943137">Cardiometabolic risk and subclinical vascular damage assessment in idiopathic inflammatory myopathies: a challenge for the clinician.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Barsotti S,
|
||
Saponaro C,
|
||
Gaggini M,
|
||
Talarico R,
|
||
Bianchini E,
|
||
Di Lascio N,
|
||
Ferrari C,
|
||
Buzzigoli E,
|
||
Mosca M,
|
||
Gastaldelli A,
|
||
Neri R,
|
||
Morales MA</span><br />
|
||
<span class="medgenPMjournal">Clin Exp Rheumatol</span>
|
||
2019 Nov-Dec;37(6):1036-1043.
|
||
Epub 2019 Mar 18
|
||
<span class="bold">PMID: </span><a href="/pubmed/30943137" target="_blank">30943137</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12506780">Idiopathic inflammatory myopathy: management and prognosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Oddis CV</span><br />
|
||
<span class="medgenPMjournal">Rheum Dis Clin North Am</span>
|
||
2002 Nov;28(4):979-1001.
|
||
doi: 10.1016/s0889-857x(02)00028-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12506780" target="_blank">12506780</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22myositis%20disease%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (5)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39284778">Adenosine A2B receptor activation regulates the balance between T helper 17 cells and regulatory T cells, and inhibits regulatory T cells exhaustion in experimental autoimmune myositis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhou Y,
|
||
Kang L,
|
||
Yin G,
|
||
Yang L,
|
||
Chen B,
|
||
Liu B,
|
||
Zhu X,
|
||
Xie Q</span><br />
|
||
<span class="medgenPMjournal">J Cachexia Sarcopenia Muscle</span>
|
||
2024 Dec;15(6):2460-2475.
|
||
Epub 2024 Sep 16
|
||
doi: 10.1002/jcsm.13581.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39284778" target="_blank">39284778</a><a href="/pmc/articles/PMC11634480" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35404027">Thromboembolic events in idiopathic inflammatory myopathy: a retrospective study in China.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chen X,
|
||
Huang S,
|
||
Jin Q,
|
||
Ge Y,
|
||
Lei J,
|
||
Huang Z,
|
||
Zhang L,
|
||
Wang G</span><br />
|
||
<span class="medgenPMjournal">Clin Rheumatol</span>
|
||
2022 Aug;41(8):2431-2438.
|
||
Epub 2022 Apr 11
|
||
doi: 10.1007/s10067-022-06140-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35404027" target="_blank">35404027</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33026081">Hand-held dynamometry for assessment of muscle strength in patients with inflammatory myopathies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Saygin D,
|
||
Oddis CV,
|
||
Moghadam-Kia S,
|
||
Rockette-Wagner B,
|
||
Neiman N,
|
||
Koontz D,
|
||
Aggarwal R</span><br />
|
||
<span class="medgenPMjournal">Rheumatology (Oxford)</span>
|
||
2021 May 14;60(5):2146-2156.
|
||
doi: 10.1093/rheumatology/keaa419.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33026081" target="_blank">33026081</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32676923">Myositis-specific autoantibodies in adults with idiopathic inflammatory myopathy: correlations with diagnosis and disease activity.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhao L,
|
||
Su K,
|
||
Liu T,
|
||
Sun D,
|
||
Jiang Z</span><br />
|
||
<span class="medgenPMjournal">Clin Rheumatol</span>
|
||
2021 Mar;40(3):1009-1016.
|
||
Epub 2020 Jul 16
|
||
doi: 10.1007/s10067-020-05273-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32676923" target="_blank">32676923</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32845379">Lipid-lowering Therapies in Myositis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mizus MC,
|
||
Tiniakou E</span><br />
|
||
<span class="medgenPMjournal">Curr Rheumatol Rep</span>
|
||
2020 Aug 26;22(10):70.
|
||
doi: 10.1007/s11926-020-00942-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32845379" target="_blank">32845379</a><a href="/pmc/articles/PMC7986053" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Myositis%20disease%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (49)</a></div><h3 class="subhead">Diagnosis</h3>
|
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<div class="nl"><a target="_blank" href="/pubmed/34698804">Abnormal paraoxonase-1 (PON1) enzyme activity in idiopathic inflammatory myopathies.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Bae SS,
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Shahbazian A,
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Wang J,
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Golub I,
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Oganesian B,
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Dowd T,
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Vayngortin B,
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Reddy ST,
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Charles-Schoeman C</span><br />
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<span class="medgenPMjournal">Rheumatology (Oxford)</span>
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2022 May 30;61(6):2512-2523.
|
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doi: 10.1093/rheumatology/keab795.
|
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<span class="bold">PMID: </span><a href="/pubmed/34698804" target="_blank">34698804</a><a href="/pmc/articles/PMC9308379" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
||
<div class="nl"><a target="_blank" href="/pubmed/32676923">Myositis-specific autoantibodies in adults with idiopathic inflammatory myopathy: correlations with diagnosis and disease activity.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Zhao L,
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Su K,
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Liu T,
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Sun D,
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Jiang Z</span><br />
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<span class="medgenPMjournal">Clin Rheumatol</span>
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2021 Mar;40(3):1009-1016.
|
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Epub 2020 Jul 16
|
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doi: 10.1007/s10067-020-05273-3.
|
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<span class="bold">PMID: </span><a href="/pubmed/32676923" target="_blank">32676923</a></div>
|
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|
||
<div class="nl"><a target="_blank" href="/pubmed/32845379">Lipid-lowering Therapies in Myositis.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Mizus MC,
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Tiniakou E</span><br />
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<span class="medgenPMjournal">Curr Rheumatol Rep</span>
|
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2020 Aug 26;22(10):70.
|
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doi: 10.1007/s11926-020-00942-3.
|
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<span class="bold">PMID: </span><a href="/pubmed/32845379" target="_blank">32845379</a><a href="/pmc/articles/PMC7986053" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
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<div class="nl"><a target="_blank" href="/pubmed/26285103">Novel serology testing for sporadic inclusion body myositis: disease-specificity and diagnostic utility.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Herbert MK,
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Pruijn GJ</span><br />
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<span class="medgenPMjournal">Curr Opin Rheumatol</span>
|
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2015 Nov;27(6):595-600.
|
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doi: 10.1097/BOR.0000000000000216.
|
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<span class="bold">PMID: </span><a href="/pubmed/26285103" target="_blank">26285103</a></div>
|
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|
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<div class="nl"><a target="_blank" href="/pubmed/22588740">Measures of adult and juvenile dermatomyositis, polymyositis, and inclusion body myositis: Physician and Patient/Parent Global Activity, Manual Muscle Testing (MMT), Health Assessment Questionnaire (HAQ)/Childhood Health Assessment Questionnaire (C-HAQ), Childhood Myositis Assessment Scale (CMAS), Myositis Disease Activity Assessment Tool (MDAAT), Disease Activity Score (DAS), Short Form 36 (SF-36), Child Health Questionnaire (CHQ), physician global damage, Myositis Damage Index (MDI), Quantitative Muscle Testing (QMT), Myositis Functional Index-2 (FI-2), Myositis Activities Profile (MAP), Inclusion Body Myositis Functional Rating Scale (IBMFRS), Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI), Cutaneous Assessment Tool (CAT), Dermatomyositis Skin Severity Index (DSSI), Skindex, and Dermatology Life Quality Index (DLQI).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rider LG,
|
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Werth VP,
|
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Huber AM,
|
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Alexanderson H,
|
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Rao AP,
|
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Ruperto N,
|
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Herbelin L,
|
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Barohn R,
|
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Isenberg D,
|
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Miller FW</span><br />
|
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<span class="medgenPMjournal">Arthritis Care Res (Hoboken)</span>
|
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2011 Nov;63 Suppl 11(0 11):S118-57.
|
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doi: 10.1002/acr.20532.
|
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<span class="bold">PMID: </span><a href="/pubmed/22588740" target="_blank">22588740</a><a href="/pmc/articles/PMC3748930" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Myositis%20disease%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (43)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35383556">Transcranial direct current stimulation is safe and effective in autoimmune myopathies: a randomised, double-blind, sham-controlled trial.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">de Sousa LFA,
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Missé RG,
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Dos Santos LM,
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<span class="medgenPMjournal">Clin Exp Rheumatol</span>
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2023 Mar;41(2):221-229.
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Epub 2022 Mar 30
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doi: 10.55563/clinexprheumatol/qjm9hb.
|
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<span class="bold">PMID: </span><a href="/pubmed/35383556" target="_blank">35383556</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35404027">Thromboembolic events in idiopathic inflammatory myopathy: a retrospective study in China.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Chen X,
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Huang S,
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Jin Q,
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Ge Y,
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Lei J,
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Huang Z,
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Zhang L,
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Wang G</span><br />
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<span class="medgenPMjournal">Clin Rheumatol</span>
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2022 Aug;41(8):2431-2438.
|
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Epub 2022 Apr 11
|
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doi: 10.1007/s10067-022-06140-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35404027" target="_blank">35404027</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32845379">Lipid-lowering Therapies in Myositis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mizus MC,
|
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Tiniakou E</span><br />
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<span class="medgenPMjournal">Curr Rheumatol Rep</span>
|
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2020 Aug 26;22(10):70.
|
||
doi: 10.1007/s11926-020-00942-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32845379" target="_blank">32845379</a><a href="/pmc/articles/PMC7986053" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27837048">Cutaneous improvement in refractory adult and juvenile dermatomyositis after treatment with rituximab.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Aggarwal R,
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Loganathan P,
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Koontz D,
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Qi Z,
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Reed AM,
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Oddis CV</span><br />
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<span class="medgenPMjournal">Rheumatology (Oxford)</span>
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2017 Feb;56(2):247-254.
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Epub 2016 Nov 11
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doi: 10.1093/rheumatology/kew396.
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<span class="bold">PMID: </span><a href="/pubmed/27837048" target="_blank">27837048</a><a href="/pmc/articles/PMC5854037" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22736096">The PRINTO criteria for clinically inactive disease in juvenile dermatomyositis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Lazarevic D,
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Pistorio A,
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Palmisani E,
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Miettunen P,
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Ravelli A,
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Pilkington C,
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Wulffraat NM,
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Malattia C,
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Garay SM,
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Hofer M,
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Quartier P,
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Dolezalova P,
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Penades IC,
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Ferriani VP,
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Ganser G,
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Kasapcopur O,
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Melo-Gomes JA,
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Reed AM,
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Wierzbowska M,
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Rider LG,
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Martini A,
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Ruperto N;
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Paediatric Rheumatology International Trials Organisation (PRINTO)</span><br />
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<span class="medgenPMjournal">Ann Rheum Dis</span>
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2013 May;72(5):686-93.
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Epub 2012 Jun 26
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<span class="bold">PMID: </span><a href="/pubmed/22736096" target="_blank">22736096</a><a href="/pmc/articles/PMC5040631" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Myositis%20disease%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (13)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37932407">YKL-40 serum levels are predicted by inflammatory state, age and diagnosis of idiopathic inflammatory myopathies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vázquez-Del Mercado M,
|
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Pérez-Vázquez F,
|
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Márquez-Aguirre AL,
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Martínez-García EA,
|
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Chavarria-Avila E,
|
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Ramos-Becerra CG,
|
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Aguilar-Vázquez A,
|
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Godínez-Rubí M,
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Martín-Márquez BT,
|
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Gómez-Limón L,
|
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Márquez-De-La-Paz G,
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Rubio-Arellano ED,
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Pizano-Martinez O</span><br />
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<span class="medgenPMjournal">Sci Rep</span>
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2023 Nov 6;13(1):19172.
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doi: 10.1038/s41598-023-46491-4.
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<span class="bold">PMID: </span><a href="/pubmed/37932407" target="_blank">37932407</a><a href="/pmc/articles/PMC10628093" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37006269">Type I interferon score is associated with the severity and poor prognosis in anti-MDA5 antibody-positive dermatomyositis patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Qian J,
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Li R,
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Chen Z,
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Cao Z,
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Lu L,
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Fu Q</span><br />
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<span class="medgenPMjournal">Front Immunol</span>
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2023;14:1151695.
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Epub 2023 Mar 17
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doi: 10.3389/fimmu.2023.1151695.
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<span class="bold">PMID: </span><a href="/pubmed/37006269" target="_blank">37006269</a><a href="/pmc/articles/PMC10063972" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35404027">Thromboembolic events in idiopathic inflammatory myopathy: a retrospective study in China.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chen X,
|
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Huang S,
|
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Jin Q,
|
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Ge Y,
|
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Lei J,
|
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Huang Z,
|
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Zhang L,
|
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Wang G</span><br />
|
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<span class="medgenPMjournal">Clin Rheumatol</span>
|
||
2022 Aug;41(8):2431-2438.
|
||
Epub 2022 Apr 11
|
||
doi: 10.1007/s10067-022-06140-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35404027" target="_blank">35404027</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33038783">Dysphonia and dysphagia as early manifestations of autoimmune inflammatory myopathy.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Weinreb SF,
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Piersiala K,
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Hillel AT,
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Akst LM,
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Best SR</span><br />
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<span class="medgenPMjournal">Am J Otolaryngol</span>
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2021 Jan-Feb;42(1):102747.
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Epub 2020 Oct 3
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doi: 10.1016/j.amjoto.2020.102747.
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<span class="bold">PMID: </span><a href="/pubmed/33038783" target="_blank">33038783</a><a href="/pmc/articles/PMC7722093" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7719899">Laboratory evaluation of the inflammatory myopathies.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Rider LG,
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Miller FW</span><br />
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<span class="medgenPMjournal">Clin Diagn Lab Immunol</span>
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<span class="bold">PMID: </span><a href="/pubmed/7719899" target="_blank">7719899</a><a href="/pmc/articles/PMC170091" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Myositis%20disease%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (29)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
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<div class="nl"><a target="_blank" href="/pubmed/39284778">Adenosine A2B receptor activation regulates the balance between T helper 17 cells and regulatory T cells, and inhibits regulatory T cells exhaustion in experimental autoimmune myositis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Zhou Y,
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Kang L,
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Yin G,
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Yang L,
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Chen B,
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Liu B,
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Zhu X,
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<span class="bold">PMID: </span><a href="/pubmed/39284778" target="_blank">39284778</a><a href="/pmc/articles/PMC11634480" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
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<div class="nl"><a target="_blank" href="/pubmed/38902010">Pathological autoantibody internalisation in myositis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Pinal-Fernandez I,
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Muñoz-Braceras S,
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Casal-Dominguez M,
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Pak K,
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Torres-Ruiz J,
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Musai J,
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Dell'Orso S,
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Naz F,
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Islam S,
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Cano MD,
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Matas-Garcia A,
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Padrosa J,
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Garrabou G,
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Aldecoa I,
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Espinosa G,
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Simeon-Aznar CP,
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Guillen-Del-Castillo A,
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Gil-Vila A,
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Trallero-Araguás E,
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Christopher-Stine L,
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Lloyd TE,
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Liewluck T,
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Naddaf E,
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Stenzel W,
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Greenberg SA,
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Grau JM,
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Selva-O'Callaghan A,
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Milisenda JC,
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Mammen AL</span><br />
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<span class="medgenPMjournal">Ann Rheum Dis</span>
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2024 Oct 21;83(11):1549-1560.
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<span class="bold">PMID: </span><a href="/pubmed/38902010" target="_blank">38902010</a><a href="/pmc/articles/PMC11493519" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37932407">YKL-40 serum levels are predicted by inflammatory state, age and diagnosis of idiopathic inflammatory myopathies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vázquez-Del Mercado M,
|
||
Pérez-Vázquez F,
|
||
Márquez-Aguirre AL,
|
||
Martínez-García EA,
|
||
Chavarria-Avila E,
|
||
Ramos-Becerra CG,
|
||
Aguilar-Vázquez A,
|
||
Godínez-Rubí M,
|
||
Martín-Márquez BT,
|
||
Gómez-Limón L,
|
||
Márquez-De-La-Paz G,
|
||
Rubio-Arellano ED,
|
||
Pizano-Martinez O</span><br />
|
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<span class="medgenPMjournal">Sci Rep</span>
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||
2023 Nov 6;13(1):19172.
|
||
doi: 10.1038/s41598-023-46491-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37932407" target="_blank">37932407</a><a href="/pmc/articles/PMC10628093" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33128920">Interleukin-35 in idiopathic inflammatory myopathies.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Mann H,
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Kryštůfková O,
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Zámečník J,
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Háček J,
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Hulejová H,
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Filková M,
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Vencovský J,
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<span class="medgenPMjournal">Cytokine</span>
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2021 Jan;137:155350.
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||
<span class="bold">PMID: </span><a href="/pubmed/33128920" target="_blank">33128920</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22588740">Measures of adult and juvenile dermatomyositis, polymyositis, and inclusion body myositis: Physician and Patient/Parent Global Activity, Manual Muscle Testing (MMT), Health Assessment Questionnaire (HAQ)/Childhood Health Assessment Questionnaire (C-HAQ), Childhood Myositis Assessment Scale (CMAS), Myositis Disease Activity Assessment Tool (MDAAT), Disease Activity Score (DAS), Short Form 36 (SF-36), Child Health Questionnaire (CHQ), physician global damage, Myositis Damage Index (MDI), Quantitative Muscle Testing (QMT), Myositis Functional Index-2 (FI-2), Myositis Activities Profile (MAP), Inclusion Body Myositis Functional Rating Scale (IBMFRS), Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI), Cutaneous Assessment Tool (CAT), Dermatomyositis Skin Severity Index (DSSI), Skindex, and Dermatology Life Quality Index (DLQI).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rider LG,
|
||
Werth VP,
|
||
Huber AM,
|
||
Alexanderson H,
|
||
Rao AP,
|
||
Ruperto N,
|
||
Herbelin L,
|
||
Barohn R,
|
||
Isenberg D,
|
||
Miller FW</span><br />
|
||
<span class="medgenPMjournal">Arthritis Care Res (Hoboken)</span>
|
||
2011 Nov;63 Suppl 11(0 11):S118-57.
|
||
doi: 10.1002/acr.20532.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22588740" target="_blank">22588740</a><a href="/pmc/articles/PMC3748930" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Myositis%20disease%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (49)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
|
||
|
||
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|
||
<div class=" bottom">
|
||
|
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|
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|
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|
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|
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<div class="supplemental col three_col last">
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0027121%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (3)</a></li>
|
||
<li><a href="/gtr/tests?term=C0027121%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (5)</a></li>
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<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0027121%5bDISCUI%5d" target="_blank">See all (5)</a></total></li>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22myositis%20disease%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Myositis%20disease%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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