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<!--
|
||
UID=42280
|
||
ConceptID=C0018099
|
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-->
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||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Gout</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>42280</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0018099</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Gouts</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Gout (90560007); Inflammatory disorder due to increased blood urate level (90560007)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0001997">HP:0001997</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
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<td><a href="https://monarchinitiative.org/disease/MONDO:0005393" target="_blank">MONDO:0005393</a></td></tr>
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</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet_content ln">Recurrent attacks of acute inflammatory arthritis of a joint or set of joints caused by elevated levels of uric acid in the blood which crystallize and are deposited in joints, tendons, and surrounding tissues. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0018099[DISCUI]&test_type=Clinical&redirect=true" ref="ncbi_uid=42280">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=42280" ref="ncbi_uid=42280">V</a></span></span><span class="TLline">Gout</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/1763488" ref="tree=MeSH" title="MedGen record for Abnormality of the musculoskeletal system">Abnormality of the musculoskeletal system</a></span><ul><li><span class="TLline"><a href="/medgen/867418" ref="tree=MeSH" title="MedGen record for Abnormality of the skeletal system">Abnormality of the skeletal system</a></span><ul><li><span class="TLline"><a href="/medgen/868760" ref="tree=MeSH" title="MedGen record for Abnormal skeletal morphology">Abnormal skeletal morphology</a></span><ul><li><span class="TLline"><a href="/medgen/893053" ref="tree=MeSH" title="MedGen record for Abnormal joint morphology">Abnormal joint morphology</a></span><ul><li><span class="TLline"><a href="/medgen/2043" ref="tree=MeSH" title="MedGen record for Arthritis">Arthritis</a></span><ul><li><span class="matched_ds">Gout</span><ul><li><span class="TLline"><a href="/medgen/406" ref="tree=MeSH" title="MedGen record for Gouty arthropathy">Gouty arthropathy</a></span></li><li><span class="TLline"><a href="/medgen/450998" ref="tree=MeSH" title="MedGen record for Podagra">Podagra</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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<div class="portlet mgSection" id="ID_112">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln clinfeat">
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||
<div class="divPopper rprt" id="rdis_5342"><div><strong>Glycogen storage disease, type VII</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>5342</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0017926</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Glycogen storage disease VII is an autosomal recessive metabolic disorder characterized clinically by exercise intolerance, muscle cramping, exertional myopathy, and compensated hemolysis. Myoglobinuria may also occur. The deficiency of the muscle isoform of PFK results in a total and partial loss of muscle and red cell PFK activity, respectively. Raben and Sherman (1995) noted that not all patients with GSD VII seek medical care because in some cases it is a relatively mild disorder.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/5342">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_78644"><div><strong>Glucose-6-phosphate transport defect</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>78644</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0268146</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Glycogen storage disease type I (GSD I) is characterized by accumulation of glycogen and fat in the liver and kidneys resulting in hepatomegaly and nephromegaly. Severely affected infants present in the neonatal period with severe hypoglycemia due to fasting intolerance. More commonly, untreated infants present at age three to four months with hepatomegaly, severe hypoglycemia with or without seizures, lactic acidosis, hyperuricemia, and hypertriglyceridemia. Affected children typically have doll-like faces with full cheeks, relatively thin extremities, short stature, and a protuberant abdomen. Xanthoma and diarrhea may be present. Impaired platelet function and development of reduced or dysfunctional von Willebrand factor can lead to a bleeding tendency with frequent epistaxis and menorrhagia in females. Individuals with untreated GSD Ib are more likely to develop impaired neutrophil and monocyte function as well as chronic neutropenia resulting in recurrent bacterial infections, gingivitis, periodontitis, and genital and intestinal ulcers. Long-term complications of untreated GSD I include short stature, osteoporosis, delayed puberty, renal disease (including proximal and distal renal tubular acidosis, renal stones, and kidney failure), gout, systemic hypertension, pulmonary hypertension, hepatic adenomas with potential for malignancy, pancreatitis, and polycystic ovaries. Seizures and cognitive impairment may occur in individuals with prolonged periods of hypoglycemia. Normal growth and puberty are expected in treated children. Most affected individuals live into adulthood.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/78644">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_87455"><div><strong>Phosphate transport defect</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>87455</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0342749</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Glycogenosis due to glucose-6-phosphatase deficiency (G6P) type b, or glycogen storage disease (GSD) type 1b, is a type of glycogenosis due to G6P deficiency (see this term).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/87455">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_96569"><div><strong>Renal cysts and diabetes syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>96569</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0431693</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">17q12 recurrent deletion syndrome is characterized by variable combinations of the three following findings: structural or functional abnormalities of the kidney and urinary tract, maturity-onset diabetes of the young type 5 (MODY5), and neurodevelopmental or neuropsychiatric disorders (e.g., developmental delay, intellectual disability, autism spectrum disorder [ASD], attention-deficit/hyperactivity disorder [ADHD], schizophrenia, anxiety, and bipolar disorder). Using a method of data analysis that avoids ascertainment bias, the authors determined that multicystic kidneys and other structural and functional kidney anomalies occur in 85%-90% of affected individuals, MODY5 in approximately 40%, and some degree of developmental delay or learning disability in approximately 50%. MODY5 is most often diagnosed before age 25 years (range: age 10-50 years).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/96569">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_343516"><div><strong>Glycoprotein storage disease</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>343516</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1856275</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/343516">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_358137"><div><strong>Tubulointerstitial kidney disease, autosomal dominant, 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>358137</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1868139</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Autosomal dominant tubulointerstitial kidney disease – MUC1 (ADTKD-MUC1) is characterized by slowly progressive tubulointerstitial disease that leads to end-stage renal disease (ESRD) and the need for dialysis or kidney transplantation. The rate of loss of kidney function for individuals is variable within and between families, with a median age of onset of end-stage renal disease (ESRD) of 46 years (range: ages 20-70 years). There are no other systemic manifestations.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/358137">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_370259"><div><strong>Coronary artery disease, autosomal dominant 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>370259</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1970440</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Any coronary artery disease in which the cause of the disease is a mutation in the LRP6 gene.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/370259">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_370358"><div><strong>Phosphoribosylpyrophosphate synthetase superactivity</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>370358</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1970827</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Phosphoribosylpyrophosphate synthetase (PRS) superactivity comprises two phenotypes, both characterized by hyperuricemia and hyperuricosuria. The mild phenotype (~75% of affected males) with onset in the second or third decade of life is typically limited to these biochemical findings, whereas the severe phenotype (~25% of affected males) with onset in the first decade of life has in addition to these biochemical findings variable combinations of developmental delay (DD) / intellectual disability (ID), sensorineural hearing loss, hypotonia, and ataxia. In the mild phenotype, uric acid crystalluria or a urinary stone is commonly the first clinical finding, followed later by gouty arthritis if serum urate concentration is not controlled.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/370358">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_415885"><div><strong>Glycogen storage disease due to glucose-6-phosphatase deficiency type IA</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>415885</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2919796</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Glycogen storage disease type I (GSD I) is characterized by accumulation of glycogen and fat in the liver and kidneys resulting in hepatomegaly and nephromegaly. Severely affected infants present in the neonatal period with severe hypoglycemia due to fasting intolerance. More commonly, untreated infants present at age three to four months with hepatomegaly, severe hypoglycemia with or without seizures, lactic acidosis, hyperuricemia, and hypertriglyceridemia. Affected children typically have doll-like faces with full cheeks, relatively thin extremities, short stature, and a protuberant abdomen. Xanthoma and diarrhea may be present. Impaired platelet function and development of reduced or dysfunctional von Willebrand factor can lead to a bleeding tendency with frequent epistaxis and menorrhagia in females. Individuals with untreated GSD Ib are more likely to develop impaired neutrophil and monocyte function as well as chronic neutropenia resulting in recurrent bacterial infections, gingivitis, periodontitis, and genital and intestinal ulcers. Long-term complications of untreated GSD I include short stature, osteoporosis, delayed puberty, renal disease (including proximal and distal renal tubular acidosis, renal stones, and kidney failure), gout, systemic hypertension, pulmonary hypertension, hepatic adenomas with potential for malignancy, pancreatitis, and polycystic ovaries. Seizures and cognitive impairment may occur in individuals with prolonged periods of hypoglycemia. Normal growth and puberty are expected in treated children. Most affected individuals live into adulthood.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/415885">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_934708"><div><strong>Hyperuricemic nephropathy, familial juvenile type 4</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>934708</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4310741</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Autosomal dominant tubulointerstitial kidney disease-5 (ADTKD5) is characterized by the onset of progressive chronic renal disease in the first decades of life. Mild hyperuricemia may be present, but gout, hypertension, and proteinuria are usually absent. The disease may be associated with anemia or neutropenia. Some patients may have additional findings, including poor overall growth and impaired cognitive function. Renal biopsy shows tubulointerstitial abnormalities with atrophic tubules and fibrosis; secondary glomerular abnormalities and simple cysts may also be present (summary by Bolar et al., 2016). For a discussion of genetic heterogeneity and revised nomenclature of ADTKD, see ADTKD1 (162000).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/934708">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1645893"><div><strong>Familial juvenile hyperuricemic nephropathy type 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1645893</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4551496</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Autosomal dominant tubulointerstitial kidney disease – UMOD (ADTKD-UMOD) is characterized by normal urinalysis and slowly progressive chronic kidney disease (CKD), usually first noted in the teen years and progressing to end-stage renal disease (ESRD) between the third and seventh decades. Hyperuricemia is often present from an early age, and gout (resulting from reduced kidney excretion of uric acid) occurs in the teenage years in about 8% of affected individuals and develops in 55% of affected individuals over time.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1645893">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1648469"><div><strong>Polycystic kidney disease 6 with or without polycystic liver disease</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1648469</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4748044</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Autosomal dominant polycystic kidney disease (ADPKD) is generally a late-onset multisystem disorder characterized by bilateral kidney cysts, liver cysts, and an increased risk of intracranial aneurysms. Other manifestations include: cysts in the pancreas, seminal vesicles, and arachnoid membrane; dilatation of the aortic root and dissection of the thoracic aorta; mitral valve prolapse; and abdominal wall hernias. Kidney manifestations include early-onset hypertension, kidney pain, and kidney insufficiency. Approximately 50% of individuals with ADPKD have end-stage kidney disease (ESKD) by age 60 years. The prevalence of liver cysts increases with age and occasionally results in clinically significant severe polycystic liver disease (PLD), most often in females. Overall, the prevalence of intracranial aneurysms is fivefold higher than in the general population and further increased in those with a positive family history of aneurysms or subarachnoid hemorrhage. There is substantial variability in the severity of kidney disease and other extra-kidney manifestations.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1648469">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1846436"><div><strong>Lipodystrophy, familial partial, type 8</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1846436</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5882744</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Familial partial lipodystrophy type 8 (FPLD8) is an autosomal dominant disorder characterized by abnormal distribution of subcutaneous adipose tissue. Affected individuals showed selective loss of subcutaneous adipose tissue from the limbs, resulting in a muscular appearance, beginning around 13 to 15 years of age. There is also abnormal accumulation of subcutaneous adipose tissue in the dorsal neck and face, as well as in the posterior thoracic and abdominal regions. The disorder is associated with metabolic abnormalities, including diabetes mellitus and hyperlipidemia (Garg et al., 2016). For a general description and a discussion of genetic heterogeneity of familial partial lipodystrophy (FPLD), see 151660.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1846436">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_370259" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Coronary artery disease, autosomal dominant 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1645893" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial juvenile hyperuricemic nephropathy type 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_78644" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Glucose-6-phosphate transport defect</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_415885" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Glycogen storage disease due to glucose-6-phosphatase deficiency type IA</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_5342" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Glycogen storage disease, type VII</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (13)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_343516" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Glycoprotein storage disease</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_934708" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hyperuricemic nephropathy, familial juvenile type 4</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1846436" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Lipodystrophy, familial partial, type 8</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_87455" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Phosphate transport defect</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_370358" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Phosphoribosylpyrophosphate synthetase superactivity</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1648469" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Polycystic kidney disease 6 with or without polycystic liver disease</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_96569" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Renal cysts and diabetes syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_358137" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Tubulointerstitial kidney disease, autosomal dominant, 2</a></div></span></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36041743">Gout: diagnosis and management-summary of NICE guidance.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Neilson J,
|
||
Bonnon A,
|
||
Dickson A,
|
||
Roddy E;
|
||
Guideline Committee</span><br />
|
||
<span class="medgenPMjournal">BMJ</span>
|
||
2022 Aug 30;378:o1754.
|
||
doi: 10.1136/bmj.o1754.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36041743" target="_blank">36041743</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32391934">2020 American College of Rheumatology Guideline for the Management of Gout.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">FitzGerald JD,
|
||
Dalbeth N,
|
||
Mikuls T,
|
||
Brignardello-Petersen R,
|
||
Guyatt G,
|
||
Abeles AM,
|
||
Gelber AC,
|
||
Harrold LR,
|
||
Khanna D,
|
||
King C,
|
||
Levy G,
|
||
Libbey C,
|
||
Mount D,
|
||
Pillinger MH,
|
||
Rosenthal A,
|
||
Singh JA,
|
||
Sims JE,
|
||
Smith BJ,
|
||
Wenger NS,
|
||
Bae SS,
|
||
Danve A,
|
||
Khanna PP,
|
||
Kim SC,
|
||
Lenert A,
|
||
Poon S,
|
||
Qasim A,
|
||
Sehra ST,
|
||
Sharma TSK,
|
||
Toprover M,
|
||
Turgunbaev M,
|
||
Zeng L,
|
||
Zhang MA,
|
||
Turner AS,
|
||
Neogi T</span><br />
|
||
<span class="medgenPMjournal">Arthritis Care Res (Hoboken)</span>
|
||
2020 Jun;72(6):744-760.
|
||
Epub 2020 May 11
|
||
doi: 10.1002/acr.24180.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32391934" target="_blank">32391934</a><a href="/pmc/articles/PMC10563586" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27931865">Gout: Diagnosis and treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sivera F,
|
||
Andrés M,
|
||
Quilis N</span><br />
|
||
<span class="medgenPMjournal">Med Clin (Barc)</span>
|
||
2017 Mar 22;148(6):271-276.
|
||
Epub 2016 Dec 5
|
||
doi: 10.1016/j.medcli.2016.10.019.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27931865" target="_blank">27931865</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22gout%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (1055)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/ng219" target="_blank">UK NICE Guideline NG219, Gout: diagnosis and management, 2022</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34907116">Update on gout management: what is old and what is new.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Afinogenova Y,
|
||
Danve A,
|
||
Neogi T</span><br />
|
||
<span class="medgenPMjournal">Curr Opin Rheumatol</span>
|
||
2022 Mar 1;34(2):118-124.
|
||
doi: 10.1097/BOR.0000000000000861.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34907116" target="_blank">34907116</a><a href="/pmc/articles/PMC8799507" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34125777">A comprehensive review on gout: The epidemiological trends, pathophysiology, clinical presentation, diagnosis and treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ashiq K,
|
||
Bajwa MA,
|
||
Tanveer S,
|
||
Qayyum M,
|
||
Ashiq S,
|
||
Khokhar R,
|
||
Abid F</span><br />
|
||
<span class="medgenPMjournal">J Pak Med Assoc</span>
|
||
2021 Apr;71(4):1234-1238.
|
||
doi: 10.47391/JPMA.313.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34125777" target="_blank">34125777</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33798500">Gout.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dalbeth N,
|
||
Gosling AL,
|
||
Gaffo A,
|
||
Abhishek A</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2021 May 15;397(10287):1843-1855.
|
||
Epub 2021 Mar 30
|
||
doi: 10.1016/S0140-6736(21)00569-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33798500" target="_blank">33798500</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31564298">Gout.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Perez-Ruiz F,
|
||
Dalbeth N</span><br />
|
||
<span class="medgenPMjournal">Rheum Dis Clin North Am</span>
|
||
2019 Nov;45(4):583-591.
|
||
doi: 10.1016/j.rdc.2019.08.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31564298" target="_blank">31564298</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27112094">Gout.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dalbeth N,
|
||
Merriman TR,
|
||
Stamp LK</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2016 Oct 22;388(10055):2039-2052.
|
||
Epub 2016 Apr 21
|
||
doi: 10.1016/S0140-6736(16)00346-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27112094" target="_blank">27112094</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Gout%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5087)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36041743">Gout: diagnosis and management-summary of NICE guidance.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Neilson J,
|
||
Bonnon A,
|
||
Dickson A,
|
||
Roddy E;
|
||
Guideline Committee</span><br />
|
||
<span class="medgenPMjournal">BMJ</span>
|
||
2022 Aug 30;378:o1754.
|
||
doi: 10.1136/bmj.o1754.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36041743" target="_blank">36041743</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34125777">A comprehensive review on gout: The epidemiological trends, pathophysiology, clinical presentation, diagnosis and treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ashiq K,
|
||
Bajwa MA,
|
||
Tanveer S,
|
||
Qayyum M,
|
||
Ashiq S,
|
||
Khokhar R,
|
||
Abid F</span><br />
|
||
<span class="medgenPMjournal">J Pak Med Assoc</span>
|
||
2021 Apr;71(4):1234-1238.
|
||
doi: 10.47391/JPMA.313.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34125777" target="_blank">34125777</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33798500">Gout.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dalbeth N,
|
||
Gosling AL,
|
||
Gaffo A,
|
||
Abhishek A</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2021 May 15;397(10287):1843-1855.
|
||
Epub 2021 Mar 30
|
||
doi: 10.1016/S0140-6736(21)00569-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33798500" target="_blank">33798500</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31564298">Gout.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Perez-Ruiz F,
|
||
Dalbeth N</span><br />
|
||
<span class="medgenPMjournal">Rheum Dis Clin North Am</span>
|
||
2019 Nov;45(4):583-591.
|
||
doi: 10.1016/j.rdc.2019.08.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31564298" target="_blank">31564298</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27931865">Gout: Diagnosis and treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sivera F,
|
||
Andrés M,
|
||
Quilis N</span><br />
|
||
<span class="medgenPMjournal">Med Clin (Barc)</span>
|
||
2017 Mar 22;148(6):271-276.
|
||
Epub 2016 Dec 5
|
||
doi: 10.1016/j.medcli.2016.10.019.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27931865" target="_blank">27931865</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Gout%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4557)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35935936">Efficacy and Safety of Curcumin and Curcuma longa Extract in the Treatment of Arthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zeng L,
|
||
Yang T,
|
||
Yang K,
|
||
Yu G,
|
||
Li J,
|
||
Xiang W,
|
||
Chen H</span><br />
|
||
<span class="medgenPMjournal">Front Immunol</span>
|
||
2022;13:891822.
|
||
Epub 2022 Jul 22
|
||
doi: 10.3389/fimmu.2022.891822.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35935936" target="_blank">35935936</a><a href="/pmc/articles/PMC9353077" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32179896">Uric Acid and Hypertension: An Update With Recommendations.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sanchez-Lozada LG,
|
||
Rodriguez-Iturbe B,
|
||
Kelley EE,
|
||
Nakagawa T,
|
||
Madero M,
|
||
Feig DI,
|
||
Borghi C,
|
||
Piani F,
|
||
Cara-Fuentes G,
|
||
Bjornstad P,
|
||
Lanaspa MA,
|
||
Johnson RJ</span><br />
|
||
<span class="medgenPMjournal">Am J Hypertens</span>
|
||
2020 Jul 18;33(7):583-594.
|
||
doi: 10.1093/ajh/hpaa044.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32179896" target="_blank">32179896</a><a href="/pmc/articles/PMC7368167" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31733140">Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tardif JC,
|
||
Kouz S,
|
||
Waters DD,
|
||
Bertrand OF,
|
||
Diaz R,
|
||
Maggioni AP,
|
||
Pinto FJ,
|
||
Ibrahim R,
|
||
Gamra H,
|
||
Kiwan GS,
|
||
Berry C,
|
||
López-Sendón J,
|
||
Ostadal P,
|
||
Koenig W,
|
||
Angoulvant D,
|
||
Grégoire JC,
|
||
Lavoie MA,
|
||
Dubé MP,
|
||
Rhainds D,
|
||
Provencher M,
|
||
Blondeau L,
|
||
Orfanos A,
|
||
L'Allier PL,
|
||
Guertin MC,
|
||
Roubille F</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2019 Dec 26;381(26):2497-2505.
|
||
Epub 2019 Nov 16
|
||
doi: 10.1056/NEJMoa1912388.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31733140" target="_blank">31733140</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28952387">The challenge of Mendelian randomization approach.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zoccali C</span><br />
|
||
<span class="medgenPMjournal">Curr Med Res Opin</span>
|
||
2017 Nov;33(sup3):5-8.
|
||
doi: 10.1080/03007995.2017.1378514.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28952387" target="_blank">28952387</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28002688">Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Montalban X,
|
||
Hauser SL,
|
||
Kappos L,
|
||
Arnold DL,
|
||
Bar-Or A,
|
||
Comi G,
|
||
de Seze J,
|
||
Giovannoni G,
|
||
Hartung HP,
|
||
Hemmer B,
|
||
Lublin F,
|
||
Rammohan KW,
|
||
Selmaj K,
|
||
Traboulsee A,
|
||
Sauter A,
|
||
Masterman D,
|
||
Fontoura P,
|
||
Belachew S,
|
||
Garren H,
|
||
Mairon N,
|
||
Chin P,
|
||
Wolinsky JS;
|
||
ORATORIO Clinical Investigators</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2017 Jan 19;376(3):209-220.
|
||
Epub 2016 Dec 21
|
||
doi: 10.1056/NEJMoa1606468.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28002688" target="_blank">28002688</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Gout%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5508)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/32620196">Gout epidemiology and comorbidities.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Singh JA,
|
||
Gaffo A</span><br />
|
||
<span class="medgenPMjournal">Semin Arthritis Rheum</span>
|
||
2020 Jun;50(3S):S11-S16.
|
||
doi: 10.1016/j.semarthrit.2020.04.008.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32620196" target="_blank">32620196</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32541923">Global epidemiology of gout: prevalence, incidence, treatment patterns and risk factors.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dehlin M,
|
||
Jacobsson L,
|
||
Roddy E</span><br />
|
||
<span class="medgenPMjournal">Nat Rev Rheumatol</span>
|
||
2020 Jul;16(7):380-390.
|
||
Epub 2020 Jun 15
|
||
doi: 10.1038/s41584-020-0441-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32541923" target="_blank">32541923</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32061315">Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">GBD Chronic Kidney Disease Collaboration</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2020 Feb 29;395(10225):709-733.
|
||
Epub 2020 Feb 13
|
||
doi: 10.1016/S0140-6736(20)30045-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32061315" target="_blank">32061315</a><a href="/pmc/articles/PMC7049905" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28919117">Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">GBD 2016 Disease and Injury Incidence and Prevalence Collaborators</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2017 Sep 16;390(10100):1211-1259.
|
||
doi: 10.1016/S0140-6736(17)32154-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28919117" target="_blank">28919117</a><a href="/pmc/articles/PMC5605509" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27112094">Gout.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dalbeth N,
|
||
Merriman TR,
|
||
Stamp LK</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2016 Oct 22;388(10055):2039-2052.
|
||
Epub 2016 Apr 21
|
||
doi: 10.1016/S0140-6736(16)00346-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27112094" target="_blank">27112094</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Gout%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2118)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38976552">Multimodal Machine Learning-Based Marker Enables Early Detection and Prognosis Prediction for Hyperuricemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zeng L,
|
||
Ma P,
|
||
Li Z,
|
||
Liang S,
|
||
Wu C,
|
||
Hong C,
|
||
Li Y,
|
||
Cui H,
|
||
Li R,
|
||
Wang J,
|
||
He J,
|
||
Li W,
|
||
Xiao L,
|
||
Liu L</span><br />
|
||
<span class="medgenPMjournal">Adv Sci (Weinh)</span>
|
||
2024 Sep;11(34):e2404047.
|
||
Epub 2024 Jul 8
|
||
doi: 10.1002/advs.202404047.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38976552" target="_blank">38976552</a><a href="/pmc/articles/PMC11425915" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38458626">How common are side effects of treatment to prevent gout flares when starting allopurinol?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Saul H,
|
||
Deeney B,
|
||
Swaithes L,
|
||
Roddy E</span><br />
|
||
<span class="medgenPMjournal">BMJ</span>
|
||
2024 Mar 8;384:q514.
|
||
doi: 10.1136/bmj.q514.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38458626" target="_blank">38458626</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33982892">Assessing the Causal Relationships Between Insulin Resistance and Hyperuricemia and Gout Using Bidirectional Mendelian Randomization.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McCormick N,
|
||
O'Connor MJ,
|
||
Yokose C,
|
||
Merriman TR,
|
||
Mount DB,
|
||
Leong A,
|
||
Choi HK</span><br />
|
||
<span class="medgenPMjournal">Arthritis Rheumatol</span>
|
||
2021 Nov;73(11):2096-2104.
|
||
Epub 2021 Sep 26
|
||
doi: 10.1002/art.41779.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33982892" target="_blank">33982892</a><a href="/pmc/articles/PMC8568618" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28631607">One year in review 2017: ultrasound in crystal arthritis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Naredo E,
|
||
Iagnocco A</span><br />
|
||
<span class="medgenPMjournal">Clin Exp Rheumatol</span>
|
||
2017 May-Jun;35(3):362-367.
|
||
Epub 2017 Jun 7
|
||
<span class="bold">PMID: </span><a href="/pubmed/28631607" target="_blank">28631607</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25738250">Autosomal dominant tubulointerstitial kidney disease: diagnosis, classification, and management--A KDIGO consensus report.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Eckardt KU,
|
||
Alper SL,
|
||
Antignac C,
|
||
Bleyer AJ,
|
||
Chauveau D,
|
||
Dahan K,
|
||
Deltas C,
|
||
Hosking A,
|
||
Kmoch S,
|
||
Rampoldi L,
|
||
Wiesener M,
|
||
Wolf MT,
|
||
Devuyst O;
|
||
Kidney Disease: Improving Global Outcomes</span><br />
|
||
<span class="medgenPMjournal">Kidney Int</span>
|
||
2015 Oct;88(4):676-83.
|
||
Epub 2015 Mar 4
|
||
doi: 10.1038/ki.2015.28.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25738250" target="_blank">25738250</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Gout%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2980)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/37019448">Dietary sugar consumption and health: umbrella review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Huang Y,
|
||
Chen Z,
|
||
Chen B,
|
||
Li J,
|
||
Yuan X,
|
||
Li J,
|
||
Wang W,
|
||
Dai T,
|
||
Chen H,
|
||
Wang Y,
|
||
Wang R,
|
||
Wang P,
|
||
Guo J,
|
||
Dong Q,
|
||
Liu C,
|
||
Wei Q,
|
||
Cao D,
|
||
Liu L</span><br />
|
||
<span class="medgenPMjournal">BMJ</span>
|
||
2023 Apr 5;381:e071609.
|
||
doi: 10.1136/bmj-2022-071609.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37019448" target="_blank">37019448</a><a href="/pmc/articles/PMC10074550" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35984830">Identified risk factors for dry eye syndrome: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Qian L,
|
||
Wei W</span><br />
|
||
<span class="medgenPMjournal">PLoS One</span>
|
||
2022;17(8):e0271267.
|
||
Epub 2022 Aug 19
|
||
doi: 10.1371/journal.pone.0271267.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35984830" target="_blank">35984830</a><a href="/pmc/articles/PMC9390932" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35935936">Efficacy and Safety of Curcumin and Curcuma longa Extract in the Treatment of Arthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zeng L,
|
||
Yang T,
|
||
Yang K,
|
||
Yu G,
|
||
Li J,
|
||
Xiang W,
|
||
Chen H</span><br />
|
||
<span class="medgenPMjournal">Front Immunol</span>
|
||
2022;13:891822.
|
||
Epub 2022 Jul 22
|
||
doi: 10.3389/fimmu.2022.891822.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35935936" target="_blank">35935936</a><a href="/pmc/articles/PMC9353077" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30485934">Dietary factors and risk of gout and hyperuricemia: a meta-analysis and systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Li R,
|
||
Yu K,
|
||
Li C</span><br />
|
||
<span class="medgenPMjournal">Asia Pac J Clin Nutr</span>
|
||
2018;27(6):1344-1356.
|
||
doi: 10.6133/apjcn.201811_27(6).0022.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30485934" target="_blank">30485934</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27457514">2016 updated EULAR evidence-based recommendations for the management of gout.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Richette P,
|
||
Doherty M,
|
||
Pascual E,
|
||
Barskova V,
|
||
Becce F,
|
||
Castañeda-Sanabria J,
|
||
Coyfish M,
|
||
Guillo S,
|
||
Jansen TL,
|
||
Janssens H,
|
||
Lioté F,
|
||
Mallen C,
|
||
Nuki G,
|
||
Perez-Ruiz F,
|
||
Pimentao J,
|
||
Punzi L,
|
||
Pywell T,
|
||
So A,
|
||
Tausche AK,
|
||
Uhlig T,
|
||
Zavada J,
|
||
Zhang W,
|
||
Tubach F,
|
||
Bardin T</span><br />
|
||
<span class="medgenPMjournal">Ann Rheum Dis</span>
|
||
2017 Jan;76(1):29-42.
|
||
Epub 2016 Jul 25
|
||
doi: 10.1136/annrheumdis-2016-209707.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27457514" target="_blank">27457514</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Gout%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (317)</a></div></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0018099%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (1)</a></li>
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