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<!--
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UID=383783
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ConceptID=C1855843
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Severe intrauterine growth retardation</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>383783</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1855843</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Intrauterine growth retardation, severe; Severe prenatal growth deficiency</td></tr>
|
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<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0008846">HP:0008846</a></td></tr>
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<div class="portlet_content ln">Intrauterine growth retardation that is 4 or more standard deviations below average, corrected for sex and gestational age. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Severe intrauterine growth retardation</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/14319" ref="tree=MeSH" title="MedGen record for Congenital, Hereditary, and Neonatal Diseases and Abnormalities">Congenital, Hereditary, and Neonatal Diseases and Abnormalities</a></span><ul><li><span class="TLline"><a href="/medgen/8822" ref="tree=MeSH" title="MedGen record for Fetal disorder">Fetal disorder</a></span><ul><li><span class="TLline"><a href="/medgen/4693" ref="tree=MeSH" title="MedGen record for Fetal growth restriction">Fetal growth restriction</a></span><ul><li><span class="matched_ds">Severe intrauterine growth retardation</span></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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</div>
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<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_59798"><div><strong>Johanson-Blizzard syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>59798</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0175692</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Johanson-Blizzard syndrome (JBS) is an autosomal recessive disorder characterized by poor growth, impaired intellectual development, and variable dysmorphic features, including aplasia or hypoplasia of the nasal alae, abnormal hair patterns or scalp defects, and oligodontia. Other features include hypothyroidism, sensorineural hearing loss, imperforate anus, and pancreatic exocrine insufficiency (summary by Al-Dosari et al., 2008).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/59798">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_120532"><div><strong>Baller-Gerold syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>120532</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0265308</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Baller-Gerold syndrome (BGS) can be suspected at birth in an infant with craniosynostosis and upper limb abnormality. The coronal suture is most commonly affected; the metopic, lambdoid, and sagittal sutures may also be involved alone or in combination. Upper limb abnormality can include a combination of thumb hypo- or aplasia and radial hypo- or aplasia and may be asymmetric. Malformation or absence of carpal or metacarpal bones has also been described. Skin lesions may appear anytime within the first few years after birth, typically beginning with erythema of the face and extremities and evolving into poikiloderma. Slow growth is apparent in infancy with eventual height and length typically at 4 SD below the mean.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/120532">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_95931"><div><strong>Roberts-SC phocomelia syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>95931</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0392475</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">ESCO2 spectrum disorder is characterized by mild-to-severe prenatal growth restriction, limb malformations (which can include bilateral symmetric tetraphocomelia or hypomelia caused by mesomelic shortening), hand anomalies (including oligodactyly, thumb aplasia or hypoplasia, and syndactyly), elbow and knee flexion contractures (involving elbows, wrists, knees, ankles, and feet [talipes equinovarus]), and craniofacial abnormalities (which can include bilateral cleft lip and/or cleft palate, micrognathia, widely spaced eyes, exophthalmos, downslanted palpebral fissures, malar flattening, and underdeveloped ala nasi), ear malformation, and corneal opacities. Intellectual disability (ranging from mild to severe) is common. Early mortality is common among severely affected pregnancies and newborns; mildly affected individuals may survive to adulthood.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/95931">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_332288"><div><strong>Permanent neonatal diabetes mellitus-pancreatic and cerebellar agenesis syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>332288</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1836780</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Permanent neonatal diabetes mellitus-pancreatic and cerebellar agenesis syndrome is characterized by neonatal diabetes mellitus associated with cerebellar and/or pancreatic agenesis.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/332288">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_340984"><div><strong>Hypoparathyroidism-retardation-dysmorphism syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>340984</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1855840</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hypoparathyroidism-retardation-dysmorphism syndrome (HRDS) is an autosomal recessive multisystem disorder characterized by intrauterine and postnatal growth retardation, infantile-onset hypoparathyroidism that can result in severe hypocalcemic seizures, dysmorphic facial features, and developmental delay (summary by Padidela et al., 2009 and Ratbi et al., 2015).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/340984">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_481473"><div><strong>Mosaic variegated aneuploidy syndrome 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>481473</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3279843</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Mosaic variegated aneuploidy syndrome is an autosomal recessive disorder characterized by poor growth and variable phenotypic manifestations, such as facial dysmorphism and congenital heart defects, associated with mosaic aneuploidies resulting from defects in cell division (summary by Snape et al., 2011). See also MVA1 (257300), caused by mutation in the BUB1B gene (602860) on chromosome 15q15.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/481473">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1844202"><div><strong>Spondyloepimetaphyseal dysplasia, Guo-Campeau type</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1844202</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5882737</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The Guo-Campeau type of spondyloepimetaphyseal dysplasia (SEMDGC) is characterized by severe bone dysplasia resulting in significant short stature with variable anomalies of the spine, pelvis, hips, and extremities, including short, rudimentary, or absent digits. Patients also exhibit variable facial dysmorphisms (Guo et al., 2023). Biallelic null mutations in the ERI1 gene have been reported to cause a less severe disorder, Hoxha-Alia syndrome, involving digital anomalies and mild intellectual disability (HXAL; 620662).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1844202">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_120532" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Baller-Gerold syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_340984" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hypoparathyroidism-retardation-dysmorphism syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_59798" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Johanson-Blizzard syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_481473" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Mosaic variegated aneuploidy syndrome 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_332288" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Permanent neonatal diabetes mellitus-pancreatic and cerebellar agenesis syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_95931" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Roberts-SC phocomelia syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1844202" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Spondyloepimetaphyseal dysplasia, Guo-Campeau type</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/10544228">The spectrum of Silver-Russell syndrome: a clinical and molecular genetic study and new diagnostic criteria.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Price SM,
|
||
Stanhope R,
|
||
Garrett C,
|
||
Preece MA,
|
||
Trembath RC</span><br />
|
||
<span class="medgenPMjournal">J Med Genet</span>
|
||
1999 Nov;36(11):837-42.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10544228" target="_blank">10544228</a><a href="/pmc/articles/PMC1734267" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7501350">Expectant management of twin pregnancies discordant for anencephaly.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lipitz S,
|
||
Meizner I,
|
||
Yagel S,
|
||
Shapiro I,
|
||
Achiron R,
|
||
Schiff E</span><br />
|
||
<span class="medgenPMjournal">Obstet Gynecol</span>
|
||
1995 Dec;86(6):969-72.
|
||
doi: 10.1016/0029-7844(95)00309-F.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7501350" target="_blank">7501350</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/503390">The management of severe toxemia in patients at less than 36 weeks' gestation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Martin TR,
|
||
Tupper WR</span><br />
|
||
<span class="medgenPMjournal">Obstet Gynecol</span>
|
||
1979 Nov;54(5):602-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/503390" target="_blank">503390</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22severe%20intrauterine%20growth%20retardation%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (3)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37758168">PHGDH-related microcephalic dwarfism in two fetuses: Expanding the phenotypical spectrum of L-serine biosynthesis defect.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cuinat S,
|
||
Quélin C,
|
||
Pasquier L,
|
||
Loget P,
|
||
Aussel D,
|
||
Odent S,
|
||
Laquerrière A,
|
||
Proisy M,
|
||
Mazoyer S,
|
||
Delous M,
|
||
Edery P,
|
||
Chatron N,
|
||
Lesca G,
|
||
Putoux A</span><br />
|
||
<span class="medgenPMjournal">Eur J Med Genet</span>
|
||
2023 Nov;66(11):104852.
|
||
Epub 2023 Sep 25
|
||
doi: 10.1016/j.ejmg.2023.104852.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37758168" target="_blank">37758168</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33069913">Pregnancy after chemoradiotherapy in childhood: Complications and recommendations - about one case.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Verhaeghe C,
|
||
Decanter C,
|
||
Sudour H,
|
||
Defachelles AS,
|
||
Escande A,
|
||
Grabarz A,
|
||
Garabedian C,
|
||
Debarge V</span><br />
|
||
<span class="medgenPMjournal">J Gynecol Obstet Hum Reprod</span>
|
||
2021 Jan;50(1):101947.
|
||
Epub 2020 Oct 16
|
||
doi: 10.1016/j.jogoh.2020.101947.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33069913" target="_blank">33069913</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15218286">SARS in newborns and children.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ng PC,
|
||
Leung CW,
|
||
Chiu WK,
|
||
Wong SF,
|
||
Hon EK</span><br />
|
||
<span class="medgenPMjournal">Biol Neonate</span>
|
||
2004;85(4):293-8.
|
||
Epub 2004 Jun 8
|
||
doi: 10.1159/000078174.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15218286" target="_blank">15218286</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/1468177">Cardiothoracic ratio in newborns with severe intrauterine growth retardation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Batton DG,
|
||
Roberts C,
|
||
Cacciarelli A</span><br />
|
||
<span class="medgenPMjournal">Clin Pediatr (Phila)</span>
|
||
1992 Sep;31(9):564-5.
|
||
doi: 10.1177/000992289203100912.
|
||
<span class="bold">PMID: </span><a href="/pubmed/1468177" target="_blank">1468177</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2184812">Tuberous sclerosis in pregnancy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Petrikovsky BM,
|
||
Vintzileos AM,
|
||
Cassidy SB,
|
||
Egan JF</span><br />
|
||
<span class="medgenPMjournal">Am J Perinatol</span>
|
||
1990 Apr;7(2):133-5.
|
||
doi: 10.1055/s-2007-999464.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2184812" target="_blank">2184812</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Severe%20intrauterine%20growth%20retardation%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (56)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36863687">Management and survival of foetuses with trisomy 18 in a French retrospective cohort.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bouzaglou A,
|
||
Dumery G,
|
||
Letourneau A,
|
||
Benachi A,
|
||
Vivanti AJ,
|
||
Cordier AG</span><br />
|
||
<span class="medgenPMjournal">J Gynecol Obstet Hum Reprod</span>
|
||
2023 Apr;52(4):102565.
|
||
Epub 2023 Mar 1
|
||
doi: 10.1016/j.jogoh.2023.102565.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36863687" target="_blank">36863687</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32274916">Congenital diabetes mellitus.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Iafusco D,
|
||
Zanfardino A,
|
||
Bonfanti R,
|
||
Rabbone I,
|
||
Tinto N,
|
||
Iafusco F,
|
||
Meola S,
|
||
Gicchino MF,
|
||
Ozen G,
|
||
Casaburo F,
|
||
Piscopo A,
|
||
Miraglia Del Giudice E,
|
||
Barbetti F</span><br />
|
||
<span class="medgenPMjournal">Minerva Pediatr</span>
|
||
2020 Aug;72(4):240-249.
|
||
Epub 2020 Apr 9
|
||
doi: 10.23736/S0026-4946.20.05838-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32274916" target="_blank">32274916</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15218286">SARS in newborns and children.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ng PC,
|
||
Leung CW,
|
||
Chiu WK,
|
||
Wong SF,
|
||
Hon EK</span><br />
|
||
<span class="medgenPMjournal">Biol Neonate</span>
|
||
2004;85(4):293-8.
|
||
Epub 2004 Jun 8
|
||
doi: 10.1159/000078174.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15218286" target="_blank">15218286</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2798352">Trisomic 22 placenta in a case of severe intrauterine growth retardation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Stioui S,
|
||
de Silvestris M,
|
||
Molinari A,
|
||
Stripparo L,
|
||
Ghisoni L,
|
||
Simoni G</span><br />
|
||
<span class="medgenPMjournal">Prenat Diagn</span>
|
||
1989 Sep;9(9):673-6.
|
||
doi: 10.1002/pd.1970090911.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2798352" target="_blank">2798352</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7143876">Late prenatal diagnosis of fetal trisomy 18 associated with severe intrauterine growth retardation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Johnson TR Jr,
|
||
Corson VL,
|
||
Payne PA,
|
||
Stetten G</span><br />
|
||
<span class="medgenPMjournal">Johns Hopkins Med J</span>
|
||
1982 Nov;151(5):242-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7143876" target="_blank">7143876</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Severe%20intrauterine%20growth%20retardation%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (71)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34154497">Pravastatin is useful for prevention of recurrent severe placenta-mediated complications - a pilot study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kupferminc MJ,
|
||
Kliger C,
|
||
Rimon E,
|
||
Asher-Landsberg J,
|
||
Skornick-Rapaport A,
|
||
Gamzu R,
|
||
Yogev Y</span><br />
|
||
<span class="medgenPMjournal">J Matern Fetal Neonatal Med</span>
|
||
2022 Dec;35(25):8055-8061.
|
||
Epub 2021 Jun 21
|
||
doi: 10.1080/14767058.2021.1940940.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34154497" target="_blank">34154497</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32274916">Congenital diabetes mellitus.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Iafusco D,
|
||
Zanfardino A,
|
||
Bonfanti R,
|
||
Rabbone I,
|
||
Tinto N,
|
||
Iafusco F,
|
||
Meola S,
|
||
Gicchino MF,
|
||
Ozen G,
|
||
Casaburo F,
|
||
Piscopo A,
|
||
Miraglia Del Giudice E,
|
||
Barbetti F</span><br />
|
||
<span class="medgenPMjournal">Minerva Pediatr</span>
|
||
2020 Aug;72(4):240-249.
|
||
Epub 2020 Apr 9
|
||
doi: 10.23736/S0026-4946.20.05838-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32274916" target="_blank">32274916</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12617981">Thrombophilia and pregnancy loss.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Brenner B</span><br />
|
||
<span class="medgenPMjournal">Thromb Res</span>
|
||
2002 Nov 25;108(4):197-202.
|
||
doi: 10.1016/s0049-3848(02)00390-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12617981" target="_blank">12617981</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8938070">Maternal uniparental disomy for chromosome 2 in association with confined placental mosaicism for trisomy 2 and severe intrauterine growth retardation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Webb AL,
|
||
Sturgiss S,
|
||
Warwicker P,
|
||
Robson SC,
|
||
Goodship JA,
|
||
Wolstenholme J</span><br />
|
||
<span class="medgenPMjournal">Prenat Diagn</span>
|
||
1996 Oct;16(10):958-62.
|
||
doi: 10.1002/(SICI)1097-0223(199610)16:10<958::AID-PD971>3.0.CO;2-U.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8938070" target="_blank">8938070</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/3130929">Pregnancy after renal transplantation: severe intrauterine growth retardation during treatment with cyclosporin A.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pickrell MD,
|
||
Sawers R,
|
||
Michael J</span><br />
|
||
<span class="medgenPMjournal">Br Med J (Clin Res Ed)</span>
|
||
1988 Mar 19;296(6625):825.
|
||
doi: 10.1136/bmj.296.6625.825.
|
||
<span class="bold">PMID: </span><a href="/pubmed/3130929" target="_blank">3130929</a><a href="/pmc/articles/PMC2545108" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Severe%20intrauterine%20growth%20retardation%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (17)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/15733972">Factor VIII levels and the risk of pre-eclampsia, HELLP syndrome, pregnancy related hypertension and severe intrauterine growth retardation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Witsenburg CP,
|
||
Rosendaal FR,
|
||
Middeldorp JM,
|
||
Van der Meer FJ,
|
||
Scherjon SA</span><br />
|
||
<span class="medgenPMjournal">Thromb Res</span>
|
||
2005;115(5):387-92.
|
||
doi: 10.1016/j.thromres.2004.09.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15733972" target="_blank">15733972</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15218286">SARS in newborns and children.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ng PC,
|
||
Leung CW,
|
||
Chiu WK,
|
||
Wong SF,
|
||
Hon EK</span><br />
|
||
<span class="medgenPMjournal">Biol Neonate</span>
|
||
2004;85(4):293-8.
|
||
Epub 2004 Jun 8
|
||
doi: 10.1159/000078174.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15218286" target="_blank">15218286</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10588835">Digynic triploid infant surviving for 46 days.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hasegawa T,
|
||
Harada N,
|
||
Ikeda K,
|
||
Ishii T,
|
||
Hokuto I,
|
||
Kasai K,
|
||
Tanaka M,
|
||
Fukuzawa R,
|
||
Niikawa N,
|
||
Matsuo N</span><br />
|
||
<span class="medgenPMjournal">Am J Med Genet</span>
|
||
1999 Dec 3;87(4):306-10.
|
||
doi: 10.1002/(sici)1096-8628(19991203)87:4<306::aid-ajmg5>3.0.co;2-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10588835" target="_blank">10588835</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7949819">Agenesis of pancreas.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Voldsgaard P,
|
||
Kryger-Baggesen N,
|
||
Lisse I</span><br />
|
||
<span class="medgenPMjournal">Acta Paediatr</span>
|
||
1994 Jul;83(7):791-3.
|
||
doi: 10.1111/j.1651-2227.1994.tb13144.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7949819" target="_blank">7949819</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2184812">Tuberous sclerosis in pregnancy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Petrikovsky BM,
|
||
Vintzileos AM,
|
||
Cassidy SB,
|
||
Egan JF</span><br />
|
||
<span class="medgenPMjournal">Am J Perinatol</span>
|
||
1990 Apr;7(2):133-5.
|
||
doi: 10.1055/s-2007-999464.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2184812" target="_blank">2184812</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Severe%20intrauterine%20growth%20retardation%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (37)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37758168">PHGDH-related microcephalic dwarfism in two fetuses: Expanding the phenotypical spectrum of L-serine biosynthesis defect.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cuinat S,
|
||
Quélin C,
|
||
Pasquier L,
|
||
Loget P,
|
||
Aussel D,
|
||
Odent S,
|
||
Laquerrière A,
|
||
Proisy M,
|
||
Mazoyer S,
|
||
Delous M,
|
||
Edery P,
|
||
Chatron N,
|
||
Lesca G,
|
||
Putoux A</span><br />
|
||
<span class="medgenPMjournal">Eur J Med Genet</span>
|
||
2023 Nov;66(11):104852.
|
||
Epub 2023 Sep 25
|
||
doi: 10.1016/j.ejmg.2023.104852.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37758168" target="_blank">37758168</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32274916">Congenital diabetes mellitus.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Iafusco D,
|
||
Zanfardino A,
|
||
Bonfanti R,
|
||
Rabbone I,
|
||
Tinto N,
|
||
Iafusco F,
|
||
Meola S,
|
||
Gicchino MF,
|
||
Ozen G,
|
||
Casaburo F,
|
||
Piscopo A,
|
||
Miraglia Del Giudice E,
|
||
Barbetti F</span><br />
|
||
<span class="medgenPMjournal">Minerva Pediatr</span>
|
||
2020 Aug;72(4):240-249.
|
||
Epub 2020 Apr 9
|
||
doi: 10.23736/S0026-4946.20.05838-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32274916" target="_blank">32274916</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24859417">Insulin-like growth factors in embryonic and fetal growth and skeletal development (Review).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Agrogiannis GD,
|
||
Sifakis S,
|
||
Patsouris ES,
|
||
Konstantinidou AE</span><br />
|
||
<span class="medgenPMjournal">Mol Med Rep</span>
|
||
2014 Aug;10(2):579-84.
|
||
Epub 2014 May 21
|
||
doi: 10.3892/mmr.2014.2258.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24859417" target="_blank">24859417</a><a href="/pmc/articles/PMC4094767" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2798352">Trisomic 22 placenta in a case of severe intrauterine growth retardation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Stioui S,
|
||
de Silvestris M,
|
||
Molinari A,
|
||
Stripparo L,
|
||
Ghisoni L,
|
||
Simoni G</span><br />
|
||
<span class="medgenPMjournal">Prenat Diagn</span>
|
||
1989 Sep;9(9):673-6.
|
||
doi: 10.1002/pd.1970090911.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2798352" target="_blank">2798352</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/3261150">Interstitial dup(1p) and severe intrauterine growth retardation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dhellemmes C,
|
||
Choiset A,
|
||
Narbouton R,
|
||
Girard S,
|
||
Tapia S,
|
||
Thepot F,
|
||
Sarrut S</span><br />
|
||
<span class="medgenPMjournal">Ann Genet</span>
|
||
1988;31(2):129-31.
|
||
<span class="bold">PMID: </span><a href="/pubmed/3261150" target="_blank">3261150</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Severe%20intrauterine%20growth%20retardation%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (45)</a></div></div>
|
||
</div>
|
||
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|
||
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|
||
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|
||
<div class="supplemental col three_col last">
|
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<h2 class="offscreen_noflow">Supplemental Content</h2>
|
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Severe%20intrauterine%20growth%20retardation" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22severe%20intrauterine%20growth%20retardation%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67d3186d67c23b31e0ad21b0">Severe intrauterine growth retardation</a>
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<div class="ralinkpop offscreen_noflow">Severe intrauterine growth retardation<div class="brieflinkpopdesc"></div></div>
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<div class="tertiary">MedGen</div>
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