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<!--
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UID=343373
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ConceptID=C1855514
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Severe failure to thrive</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>343373</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1855514</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Failure to thrive, severe; Marked failure to thrive; Severe postnatal failure to thrive</td></tr>
|
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<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0001525">HP:0001525</a></td></tr>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Severe failure to thrive</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/808205" ref="tree=MeSH" title="MedGen record for Growth abnormality">Growth abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/892367" ref="tree=MeSH" title="MedGen record for Abnormality of body weight">Abnormality of body weight</a></span><ul><li><span class="TLline"><a href="/medgen/1806755" ref="tree=MeSH" title="MedGen record for Decreased body weight">Decreased body weight</a></span><ul><li><span class="TLline"><a href="/medgen/746019" ref="tree=MeSH" title="MedGen record for Failure to thrive">Failure to thrive</a></span><ul><li><span class="matched_ds">Severe failure to thrive</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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<div class="portlet mgSection" id="ID_112">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln clinfeat">
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||
<div class="divPopper rprt" id="rdis_155487"><div><strong>Cockayne syndrome type 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>155487</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0751038</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Cockayne syndrome (referred to as CS in this GeneReview) spans a continuous phenotypic spectrum that includes CS type I, the "classic" or "moderate" form; CS type II, a more severe form with symptoms present at birth (this form overlaps with cerebrooculofacioskeletal [COFS] syndrome); CS type III, a milder and later-onset form; and COFS syndrome, a fetal form of CS. CS type I is characterized by normal prenatal growth with the onset of growth and developmental abnormalities in the first two years. By the time the disease has become fully manifest, height, weight, and head circumference are far below the fifth percentile. Progressive impairment of vision, hearing, and central and peripheral nervous system function leads to severe disability; death typically occurs in the first or second decade. CS type II is characterized by growth failure at birth, with little or no postnatal neurologic development. Congenital cataracts or other structural anomalies of the eye may be present. Affected children have early postnatal contractures of the spine (kyphosis, scoliosis) and joints. Death usually occurs by age five years. CS type III is a phenotype in which major clinical features associated with CS only become apparent after age two years; growth and/or cognition exceeds the expectations for CS type I. COFS syndrome is characterized by very severe prenatal developmental anomalies (arthrogryposis and microphthalmia).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/155487">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_371317"><div><strong>Diabetes mellitus, transient neonatal, 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>371317</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C1832386</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">6q24-related transient neonatal diabetes mellitus (6q24-TNDM) is defined as transient neonatal diabetes mellitus caused by genetic aberrations of the imprinted locus at 6q24. The cardinal features are: severe intrauterine growth restriction, hyperglycemia that begins in the neonatal period in a term infant and resolves by age 18 months, dehydration, and absence of ketoacidosis. Macroglossia and umbilical hernia may be present. 6q24-TNDM associated with a multilocus imprinting disturbance (MLID) can be associated with marked hypotonia, congenital heart disease, deafness, neurologic features including epilepsy, and renal malformations. Diabetes mellitus usually starts within the first week of life and lasts on average three months but can last longer than a year. Although insulin is usually required initially, the need for insulin gradually declines over time. Intermittent episodes of hyperglycemia may occur in childhood, particularly during intercurrent illnesses. Diabetes mellitus may recur in adolescence or later in adulthood. Women who have had 6q24-TNDM are at risk for relapse during pregnancy.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/371317">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_341818"><div><strong>Yunis-Varon syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>341818</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1857663</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Yunis-Varon syndrome (YVS) is a severe autosomal recessive disorder characterized by skeletal defects, including cleidocranial dysplasia and digital anomalies, and severe neurologic involvement with neuronal loss. Enlarged cytoplasmic vacuoles are found in neurons, muscle, and cartilage. The disorder is usually lethal in infancy (summary by Campeau et al., 2013).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/341818">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_347072"><div><strong>Rhizomelic chondrodysplasia punctata type 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>347072</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1859133</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Rhizomelic chondrodysplasia punctata type 1 (RCDP1), a peroxisome biogenesis disorder (PBD) has a classic (severe) form and a nonclassic (mild) form. Classic (severe) RCDP1 is characterized by proximal shortening of the humerus (rhizomelia) and to a lesser degree the femur, punctate calcifications in cartilage with epiphyseal and metaphyseal abnormalities (chondrodysplasia punctata, or CDP), coronal clefts of the vertebral bodies, and cataracts that are usually present at birth or appear in the first few months of life. Birth weight, length, and head circumference are often at the lower range of normal; postnatal growth deficiency is profound. Intellectual disability is severe, and the majority of children develop seizures. Most affected children do not survive the first decade of life; a proportion die in the neonatal period. Nonclassic (mild) RCDP1 is characterized by congenital or childhood cataracts, CDP or infrequently, chondrodysplasia manifesting only as mild epiphyseal changes, variable rhizomelia, and milder intellectual disability and growth restriction than classic RCDP1.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/347072">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_854819"><div><strong>Seckel syndrome 4</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>854819</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3888212</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Seckel syndrome is a rare autosomal recessive disorder characterized by severe pre- and postnatal growth retardation, severe microcephaly with mental retardation, and specific dysmorphic features (Faivre et al., 2002). For a general description and a discussion of genetic heterogeneity of Seckel syndrome, see 210600.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/854819">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_155487" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cockayne syndrome type 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_371317" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Diabetes mellitus, transient neonatal, 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_347072" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Rhizomelic chondrodysplasia punctata type 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_854819" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Seckel syndrome 4</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_341818" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Yunis-Varon syndrome</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33459628">Renal tubular acidosis (RTA) and kidney stones: Diagnosis and management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Magni G,
|
||
Unwin RJ,
|
||
Moochhala SH</span><br />
|
||
<span class="medgenPMjournal">Arch Esp Urol</span>
|
||
2021 Jan;74(1):123-128.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33459628" target="_blank">33459628</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12512191">Optimal management of atopic dermatitis in infancy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Moneret-Vautrin DA</span><br />
|
||
<span class="medgenPMjournal">Allerg Immunol (Paris)</span>
|
||
2002 Nov;34(9):325-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12512191" target="_blank">12512191</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11517108">Congenital disorder of glycosylation type Ia (CDG-Ia): phenotypic spectrum of the R141H/F119L genotype.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kjaergaard S,
|
||
Schwartz M,
|
||
Skovby F</span><br />
|
||
<span class="medgenPMjournal">Arch Dis Child</span>
|
||
2001 Sep;85(3):236-9.
|
||
doi: 10.1136/adc.85.3.236.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11517108" target="_blank">11517108</a><a href="/pmc/articles/PMC1718926" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22severe%20failure%20to%20thrive%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (3)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37195341">DEGS1 -related leukodystrophy: a clinical report and review of literature.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wong MST,
|
||
Thomas T,
|
||
Lim JY,
|
||
Kam S,
|
||
Teo JX,
|
||
Ching J,
|
||
Goh CYJ,
|
||
Jamuar SS,
|
||
Lim WK,
|
||
Koh AL</span><br />
|
||
<span class="medgenPMjournal">Clin Dysmorphol</span>
|
||
2023 Jul 1;32(3):106-111.
|
||
Epub 2023 May 1
|
||
doi: 10.1097/MCD.0000000000000457.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37195341" target="_blank">37195341</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34481427">Distal Renal Tubular Acidosis in an Iranian Patient with Hereditary Spherocytosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shahab-Movahed Z,
|
||
Majd A,
|
||
Siasi Torbati E,
|
||
Zeinali S</span><br />
|
||
<span class="medgenPMjournal">Iran Biomed J</span>
|
||
2021 Sep 1;25(5):359-67.
|
||
doi: 10.52547/ibj.25.5.359.
|
||
[Epub ahead of print]
|
||
<span class="bold">PMID: </span><a href="/pubmed/34481427" target="_blank">34481427</a><a href="/pmc/articles/PMC8487683" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29148123">Donohue syndrome: A review of literature, case series, and anesthetic considerations.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kirkwood A,
|
||
Stuart G,
|
||
Harding L</span><br />
|
||
<span class="medgenPMjournal">Paediatr Anaesth</span>
|
||
2018 Jan;28(1):23-27.
|
||
Epub 2017 Nov 17
|
||
doi: 10.1111/pan.13273.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29148123" target="_blank">29148123</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11521206">Inherited disorders of cholesterol biosynthesis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Haas D,
|
||
Kelley RI,
|
||
Hoffmann GF</span><br />
|
||
<span class="medgenPMjournal">Neuropediatrics</span>
|
||
2001 Jun;32(3):113-22.
|
||
doi: 10.1055/s-2001-16618.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11521206" target="_blank">11521206</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/4042742">Behavioral treatment of failure-to-thrive in a two-year-old.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Koepke JM,
|
||
Thyer BA</span><br />
|
||
<span class="medgenPMjournal">Child Welfare</span>
|
||
1985 Sep-Oct;64(5):511-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/4042742" target="_blank">4042742</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Severe%20failure%20to%20thrive%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (29)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35780510">A 6-Month-Old Infant with Severe Failure to Thrive during COVID-19 Pandemic.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hong X,
|
||
Alharbi H,
|
||
Albokhari D,
|
||
Edmondson AC,
|
||
He M</span><br />
|
||
<span class="medgenPMjournal">Clin Chem</span>
|
||
2022 Jul 3;68(7):987-989.
|
||
doi: 10.1093/clinchem/hvac012.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35780510" target="_blank">35780510</a><a href="/pmc/articles/PMC9384345" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27771653">Infantile Achalasia Cardia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Banerjee R,
|
||
Prasad A,
|
||
Kumar V,
|
||
Wadhwa N</span><br />
|
||
<span class="medgenPMjournal">Indian Pediatr</span>
|
||
2016 Sep 8;53(9):831-832.
|
||
doi: 10.1007/s13312-016-0940-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27771653" target="_blank">27771653</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26914089">Arthrogryposis-renal tubular dysfunction-cholestasis syndrome: a cause of neonatal cholestasis. Case report.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ilhan O,
|
||
Ozer EA,
|
||
Ozdemir SA,
|
||
Akbay S,
|
||
Memur S,
|
||
Kanar B,
|
||
Tatli MM</span><br />
|
||
<span class="medgenPMjournal">Arch Argent Pediatr</span>
|
||
2016 Feb;114(1):e9-12.
|
||
doi: 10.5546/aap.2016.eng.e9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26914089" target="_blank">26914089</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/13678136">Failure to thrive.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Krugman SD,
|
||
Dubowitz H</span><br />
|
||
<span class="medgenPMjournal">Am Fam Physician</span>
|
||
2003 Sep 1;68(5):879-84.
|
||
<span class="bold">PMID: </span><a href="/pubmed/13678136" target="_blank">13678136</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9541110">Costello syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Philip N,
|
||
Sigaudy S</span><br />
|
||
<span class="medgenPMjournal">J Med Genet</span>
|
||
1998 Mar;35(3):238-40.
|
||
doi: 10.1136/jmg.35.3.238.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9541110" target="_blank">9541110</a><a href="/pmc/articles/PMC1051249" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Severe%20failure%20to%20thrive%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (70)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34935734">Fludarabine-based Reduced Intensity Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in a Pediatric Patient With Bone Marrow Failure Syndrome Type 3.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Barhoom D,
|
||
Mohseni R,
|
||
Behfar M,
|
||
Hamidieh AA</span><br />
|
||
<span class="medgenPMjournal">J Pediatr Hematol Oncol</span>
|
||
2022 Nov 1;44(8):e1050-e1052.
|
||
Epub 2021 Dec 22
|
||
doi: 10.1097/MPH.0000000000002374.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34935734" target="_blank">34935734</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33037119">Toddler With New Onset Diabetes and Atypical Hemolytic-Uremic Syndrome in the Setting of COVID-19.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Alizadeh F,
|
||
O'Halloran A,
|
||
Alghamdi A,
|
||
Chen C,
|
||
Trissal M,
|
||
Traum A,
|
||
DeCourcey D</span><br />
|
||
<span class="medgenPMjournal">Pediatrics</span>
|
||
2021 Feb;147(2)
|
||
Epub 2020 Oct 9
|
||
doi: 10.1542/peds.2020-016774.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33037119" target="_blank">33037119</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10228298">Soy allergy in infants and children with IgE-associated cow's milk allergy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zeiger RS,
|
||
Sampson HA,
|
||
Bock SA,
|
||
Burks AW Jr,
|
||
Harden K,
|
||
Noone S,
|
||
Martin D,
|
||
Leung S,
|
||
Wilson G</span><br />
|
||
<span class="medgenPMjournal">J Pediatr</span>
|
||
1999 May;134(5):614-22.
|
||
doi: 10.1016/s0022-3476(99)70249-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10228298" target="_blank">10228298</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9167027">Perforated duodenal ulcer in a pediatric patient with eosinophilic gastroenteritis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Deslandres C,
|
||
Russo P,
|
||
Gould P,
|
||
Hardy P</span><br />
|
||
<span class="medgenPMjournal">Can J Gastroenterol</span>
|
||
1997 Apr;11(3):208-12.
|
||
doi: 10.1155/1997/809363.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9167027" target="_blank">9167027</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/3415337">Severe failure to thrive and diarrhoea caused by laxative abuse.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fenton AC,
|
||
Wailoo MP,
|
||
Tanner MS</span><br />
|
||
<span class="medgenPMjournal">Arch Dis Child</span>
|
||
1988 Aug;63(8):978-9.
|
||
doi: 10.1136/adc.63.8.978.
|
||
<span class="bold">PMID: </span><a href="/pubmed/3415337" target="_blank">3415337</a><a href="/pmc/articles/PMC1778964" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Severe%20failure%20to%20thrive%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (10)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/29148123">Donohue syndrome: A review of literature, case series, and anesthetic considerations.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kirkwood A,
|
||
Stuart G,
|
||
Harding L</span><br />
|
||
<span class="medgenPMjournal">Paediatr Anaesth</span>
|
||
2018 Jan;28(1):23-27.
|
||
Epub 2017 Nov 17
|
||
doi: 10.1111/pan.13273.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29148123" target="_blank">29148123</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26914089">Arthrogryposis-renal tubular dysfunction-cholestasis syndrome: a cause of neonatal cholestasis. Case report.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ilhan O,
|
||
Ozer EA,
|
||
Ozdemir SA,
|
||
Akbay S,
|
||
Memur S,
|
||
Kanar B,
|
||
Tatli MM</span><br />
|
||
<span class="medgenPMjournal">Arch Argent Pediatr</span>
|
||
2016 Feb;114(1):e9-12.
|
||
doi: 10.5546/aap.2016.eng.e9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26914089" target="_blank">26914089</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9541110">Costello syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Philip N,
|
||
Sigaudy S</span><br />
|
||
<span class="medgenPMjournal">J Med Genet</span>
|
||
1998 Mar;35(3):238-40.
|
||
doi: 10.1136/jmg.35.3.238.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9541110" target="_blank">9541110</a><a href="/pmc/articles/PMC1051249" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7813144">Severe failure to thrive and liver dysfunction as the main manifestations of a new variant of Niemann-Pick disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Reif S,
|
||
Spirer Z,
|
||
Messer G,
|
||
Baratz M,
|
||
Bembi B,
|
||
Bujanover Y</span><br />
|
||
<span class="medgenPMjournal">Clin Pediatr (Phila)</span>
|
||
1994 Oct;33(10):628-30.
|
||
doi: 10.1177/000992289403301010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7813144" target="_blank">7813144</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7528972">10p duplication characterized by fluorescence in situ hybridization.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wiktor A,
|
||
Feldman GL,
|
||
Kratkoczki P,
|
||
Ditmars DM Jr,
|
||
Van Dyke DL</span><br />
|
||
<span class="medgenPMjournal">Am J Med Genet</span>
|
||
1994 Sep 1;52(3):315-8.
|
||
doi: 10.1002/ajmg.1320520312.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7528972" target="_blank">7528972</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Severe%20failure%20to%20thrive%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (37)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35443069">A syndrome of severe intellectual disability, hypotonia, failure to thrive, dysmorphism, and thinning of corpus callosum maps to chromosome 7q21.13-q21.3.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Halperin D,
|
||
Agam N,
|
||
Hallak M,
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Feinstein M,
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Drabkin M,
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Yogev Y,
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Wormser O,
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Shavit E,
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Gradstein L,
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Shelef I,
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Mijalovsky A,
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Flusser H,
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Birk OS</span><br />
|
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<span class="medgenPMjournal">Clin Genet</span>
|
||
2022 Aug;102(2):123-129.
|
||
Epub 2022 May 5
|
||
doi: 10.1111/cge.14143.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35443069" target="_blank">35443069</a><a href="/pmc/articles/PMC9545274" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34481427">Distal Renal Tubular Acidosis in an Iranian Patient with Hereditary Spherocytosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shahab-Movahed Z,
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||
Majd A,
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||
Siasi Torbati E,
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Zeinali S</span><br />
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<span class="medgenPMjournal">Iran Biomed J</span>
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||
2021 Sep 1;25(5):359-67.
|
||
doi: 10.52547/ibj.25.5.359.
|
||
[Epub ahead of print]
|
||
<span class="bold">PMID: </span><a href="/pubmed/34481427" target="_blank">34481427</a><a href="/pmc/articles/PMC8487683" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28238446">CTNS molecular genetics profile in a Persian nephropathic cystinosis population.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ghazi F,
|
||
Hosseini R,
|
||
Akouchekian M,
|
||
Teimourian S,
|
||
Ataei Kachoei Z,
|
||
Otukesh H,
|
||
Gahl WA,
|
||
Behnam B</span><br />
|
||
<span class="medgenPMjournal">Nefrologia</span>
|
||
2017 May-Jun;37(3):301-310.
|
||
Epub 2017 Feb 24
|
||
doi: 10.1016/j.nefro.2016.11.024.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28238446" target="_blank">28238446</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26708380">Preoperative Determinants of Outcomes of Infant Heart Surgery in a Limited-Resource Setting.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Reddy NS,
|
||
Kappanayil M,
|
||
Balachandran R,
|
||
Jenkins KJ,
|
||
Sudhakar A,
|
||
Sunil GS,
|
||
Raj RB,
|
||
Kumar RK</span><br />
|
||
<span class="medgenPMjournal">Semin Thorac Cardiovasc Surg</span>
|
||
2015 Autumn;27(3):331-8.
|
||
Epub 2015 Oct 22
|
||
doi: 10.1053/j.semtcvs.2015.09.008.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26708380" target="_blank">26708380</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24569605">Unexpected high intrafamilial phenotypic variability observed in hypophosphatasia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hofmann C,
|
||
Girschick H,
|
||
Mornet E,
|
||
Schneider D,
|
||
Jakob F,
|
||
Mentrup B</span><br />
|
||
<span class="medgenPMjournal">Eur J Hum Genet</span>
|
||
2014 Oct;22(10):1160-4.
|
||
Epub 2014 Feb 26
|
||
doi: 10.1038/ejhg.2014.10.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24569605" target="_blank">24569605</a><a href="/pmc/articles/PMC4169536" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Severe%20failure%20to%20thrive%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (24)</a></div></div>
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