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<meta name="keywords" content="C1857108, decreased joint mobility, decreased mobility of joints, finding, joint mobility decreased, limitation of joint mobility, limited joint mobility, limited joint motion, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A reduction in the freedom of movement of one or more joints." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=341696
|
||
ConceptID=C1857108
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Limitation of joint mobility</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>341696</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1857108</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Decreased joint mobility; Joint mobility decreased; Limited joint mobility; Limited joint motion</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0001376">HP:0001376</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">A reduction in the freedom of movement of one or more joints. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
|
||
</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1857108[DISCUI]&test_type=Clinical" ref="ncbi_uid=341696">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Limitation of joint mobility</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/1763488" ref="tree=MeSH" title="MedGen record for Abnormality of the musculoskeletal system">Abnormality of the musculoskeletal system</a></span><ul><li><span class="TLline"><a href="/medgen/1728335" ref="tree=MeSH" title="MedGen record for Abnormal musculoskeletal physiology">Abnormal musculoskeletal physiology</a></span><ul><li><span class="TLline"><a href="/medgen/1841757" ref="tree=MeSH" title="MedGen record for Abnormal joint physiology">Abnormal joint physiology</a></span><ul><li><span class="TLline"><a href="/medgen/868806" ref="tree=MeSH" title="MedGen record for Abnormality of joint mobility">Abnormality of joint mobility</a></span><ul><li><span class="matched_ds">Limitation of joint mobility</span><ul><li><span class="TLline"><a href="/medgen/8101" ref="tree=MeSH" title="MedGen record for Ankylosis">Ankylosis</a></span><ul><li><span class="TLline"><a href="/medgen/870290" ref="tree=MeSH" title="MedGen record for Ankylosis of feet small joints">Ankylosis of feet small joints</a></span></li><li><span class="TLline"><a href="/medgen/923672" ref="tree=MeSH" title="MedGen record for Axial spondyloarthritis">Axial spondyloarthritis</a></span><ul><li><span class="TLline"><a href="/medgen/11561" ref="tree=MeSH" title="MedGen record for Ankylosing spondylitis">Ankylosing spondylitis</a></span></li><li><span class="TLline"><a href="/medgen/891368" ref="tree=MeSH" title="MedGen record for Non-radiographic axial spondyloarthritis">Non-radiographic axial spondyloarthritis</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/592439" ref="tree=MeSH" title="MedGen record for Elbow ankylosis">Elbow ankylosis</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/56403" ref="tree=MeSH" title="MedGen record for Joint stiffness">Joint stiffness</a></span><ul><li><span class="TLline"><a href="/medgen/870781" ref="tree=MeSH" title="MedGen record for Generalized morning stiffness">Generalized morning stiffness</a></span></li><li><span class="TLline"><a href="/medgen/167911" ref="tree=MeSH" title="MedGen record for Joint Range of Motion Decreased">Joint Range of Motion Decreased</a></span><ul><li><span class="TLline"><a href="/medgen/352160" ref="tree=MeSH" title="MedGen record for Cervical Spine Joint Range of Motion Decreased">Cervical Spine Joint Range of Motion Decreased</a></span></li><li><span class="TLline"><a href="/medgen/352249" ref="tree=MeSH" title="MedGen record for Lumbar Spine Joint Range of Motion Decreased">Lumbar Spine Joint Range of Motion Decreased</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/605355" ref="tree=MeSH" title="MedGen record for Stiff ankle">Stiff ankle</a></span></li><li><span class="TLline"><a href="/medgen/536893" ref="tree=MeSH" title="MedGen record for Stiff elbow">Stiff elbow</a></span></li><li><span class="TLline"><a href="/medgen/909960" ref="tree=MeSH" title="MedGen record for Stiff finger">Stiff finger</a></span></li><li><span class="TLline"><a href="/medgen/536940" ref="tree=MeSH" title="MedGen record for Stiff hip">Stiff hip</a></span></li><li><span class="TLline"><a href="/medgen/870780" ref="tree=MeSH" title="MedGen record for Stiff interphalangeal joints">Stiff interphalangeal joints</a></span></li><li><span class="TLline"><a href="/medgen/536952" ref="tree=MeSH" title="MedGen record for Stiff knee">Stiff knee</a></span></li><li><span class="TLline"><a href="/medgen/1370540" ref="tree=MeSH" title="MedGen record for Stiff toe">Stiff toe</a></span></li><li><span class="TLline"><a href="/medgen/537095" ref="tree=MeSH" title="MedGen record for Stiff wrist">Stiff wrist</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/343601" ref="tree=MeSH" title="MedGen record for Limited hip movement">Limited hip movement</a></span><ul><li><span class="TLline"><a href="/medgen/332244" ref="tree=MeSH" title="MedGen record for Decreased hip abduction">Decreased hip abduction</a></span></li><li><span class="TLline"><a href="/medgen/766282" ref="tree=MeSH" title="MedGen record for Limited hip extension">Limited hip extension</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/870784" ref="tree=MeSH" title="MedGen record for Restricted large joint movement">Restricted large joint movement</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
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|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_10988"><div><strong>Pseudo-Hurler polydystrophy</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>10988</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0033788</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">GNPTAB-related disorders comprise the phenotypes mucolipidosis II (ML II) and mucolipidosis IIIa/ß (ML IIIa/ß), and phenotypes intermediate between ML II and ML IIIa/ß. ML II is evident at birth and slowly progressive; death most often occurs in early childhood. Orthopedic abnormalities present at birth may include thoracic deformity, kyphosis, clubfeet, deformed long bones, and/or dislocation of the hip(s). Growth often ceases in the second year of life; contractures develop in all large joints. The skin is thickened, facial features are coarse, and gingiva are hypertrophic. All children have cardiac involvement, most commonly thickening and insufficiency of the mitral valve and, less frequently, the aortic valve. Progressive mucosal thickening narrows the airways, and gradual stiffening of the thoracic cage contributes to respiratory insufficiency, the most common cause of death. ML IIIa/ß becomes evident at about age three years with slow growth rate and short stature; joint stiffness and pain initially in the shoulders, hips, and fingers; gradual mild coarsening of facial features; and normal to mildly impaired cognitive development. Pain from osteoporosis becomes more severe during adolescence. Cardiorespiratory complications (restrictive lung disease, thickening and insufficiency of the mitral and aortic valves, left and/or right ventricular hypertrophy) are common causes of death, typically in early to middle adulthood. Phenotypes intermediate between ML II and ML IIIa/ß are characterized by physical growth in infancy that resembles that of ML II and neuromotor and speech development that resemble that of ML IIIa/ß.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/10988">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_43108"><div><strong>Mucopolysaccharidosis type 7</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>43108</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0085132</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Individuals with mucopolysaccharidosis type VII (MPS VII) can present perinatally with early demise, nonimmune hydrops fetalis, cholestatic jaundice, and hepatosplenomegaly, or in early childhood with developmental delay and characteristic musculoskeletal features (e.g., short neck, short-trunk short stature, pectus deformity, gibbus, and joint stiffness/contractures) and craniofacial features (e.g., macrocephaly, coarse hair, coarse facies, corneal clouding, and macroglossia). Skeletal survey shows features of dysostosis multiplex including thickened cortical bone, abnormal J-shaped sella turcica, paddle- or oar-shaped ribs, short, thickened clavicles, platyspondyly with anterior beaking of the lower thoracic and lumbar vertebrae, and proximal pointing of the metacarpals and metatarsals. Complications include developmental delay, intellectual disability, hepatosplenomegaly, spinal stenosis, recurrent otitis media, hearing loss, pulmonary disease, obstructive sleep apnea, hernias, feeding difficulties, and heart valve disease.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/43108">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_75559"><div><strong>Kniest dysplasia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>75559</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0265279</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Kniest dysplasia is characterized by skeletal and craniofacial anomalies. Skeletal anomalies include disproportionate dwarfism, a short trunk and small pelvis, kyphoscoliosis, short limbs, and prominent joints and premature osteoarthritis that restrict movement. Craniofacial manifestations include midface hypoplasia, cleft palate, early-onset myopia, retinal detachment, and hearing loss. The phenotype is severe in some patients and mild in others. There are distinct radiographic changes including coronal clefts of vertebrae and dumbbell-shaped femora. The chondrooseous morphology is pathognomonic with perilacunar 'foaminess' and sparse, aggregated collagen fibrils resulting in an interterritorial matrix with a 'Swiss-cheese' appearance (summary by Wilkin et al., 1999).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/75559">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_120527"><div><strong>Dyggve-Melchior-Clausen syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>120527</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0265286</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Dyggve-Melchior-Clausen disease (DMC) is an autosomal recessive disorder characterized by progressive spondyloepimetaphyseal dysplasia and impaired intellectual development. Short-trunk dwarfism and microcephaly are present, and specific radiologic appearances most likely reflect abnormalities of the growth plates, including platyspondyly with notched end plates, metaphyseal irregularities, laterally displaced capital femoral epiphyses, and small iliac wings with lacy iliac crests (summary by El Ghouzzi et al., 2003).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/120527">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_98145"><div><strong>Rolland-Debuqois syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>98145</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0432209</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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||
<div class="spaceAbove">The dyssegmental dysplasias are lethal forms of neonatal short-limbed dwarfism. Handmaker et al. (1977) coined the term 'dyssegmental dysplasia' because of the marked differences in size and shape of the vertebral bodies (anisospondyly), which he attributed to errors in segmentation. Fasanelli et al. (1985) proposed that there are different forms of dyssegmental dwarfism, a lethal Silverman-Handmaker type (224410) and a less severe Rolland-Desbuquois type. The Rolland-Desbuquois form is lethal in about 40% of patients. Although many patients survive beyond the newborn period, all exhibit neonatal distress (summary by Hennekam et al., 2010).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/98145">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_140930"><div><strong>Kyphomelic dysplasia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>140930</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0432239</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Kyphomelic dysplasia (KMD) is an autosomal recessive disorder characterized by bowing of the limbs, primarily affecting the femurs. Affected individuals also exhibit short stature, short and wide iliac wings, horizontal acetabular roof, platyspondyly, and metaphyseal flaring. Distinctive facial features have been observed, including prominent forehead, micrognathia, microstomia, cleft palate, and low-set ears (Singh et al., 2025).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/140930">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_155487"><div><strong>Cockayne syndrome type 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>155487</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0751038</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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||
<div class="spaceAbove">Cockayne syndrome (referred to as CS in this GeneReview) spans a continuous phenotypic spectrum that includes CS type I, the "classic" or "moderate" form; CS type II, a more severe form with symptoms present at birth (this form overlaps with cerebrooculofacioskeletal [COFS] syndrome); CS type III, a milder and later-onset form; and COFS syndrome, a fetal form of CS. CS type I is characterized by normal prenatal growth with the onset of growth and developmental abnormalities in the first two years. By the time the disease has become fully manifest, height, weight, and head circumference are far below the fifth percentile. Progressive impairment of vision, hearing, and central and peripheral nervous system function leads to severe disability; death typically occurs in the first or second decade. CS type II is characterized by growth failure at birth, with little or no postnatal neurologic development. Congenital cataracts or other structural anomalies of the eye may be present. Affected children have early postnatal contractures of the spine (kyphosis, scoliosis) and joints. Death usually occurs by age five years. CS type III is a phenotype in which major clinical features associated with CS only become apparent after age two years; growth and/or cognition exceeds the expectations for CS type I. COFS syndrome is characterized by very severe prenatal developmental anomalies (arthrogryposis and microphthalmia).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/155487">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_155488"><div><strong>Cockayne syndrome type 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>155488</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0751039</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Cockayne syndrome (referred to as CS in this GeneReview) spans a continuous phenotypic spectrum that includes CS type I, the "classic" or "moderate" form; CS type II, a more severe form with symptoms present at birth (this form overlaps with cerebrooculofacioskeletal [COFS] syndrome); CS type III, a milder and later-onset form; and COFS syndrome, a fetal form of CS. CS type I is characterized by normal prenatal growth with the onset of growth and developmental abnormalities in the first two years. By the time the disease has become fully manifest, height, weight, and head circumference are far below the fifth percentile. Progressive impairment of vision, hearing, and central and peripheral nervous system function leads to severe disability; death typically occurs in the first or second decade. CS type II is characterized by growth failure at birth, with little or no postnatal neurologic development. Congenital cataracts or other structural anomalies of the eye may be present. Affected children have early postnatal contractures of the spine (kyphosis, scoliosis) and joints. Death usually occurs by age five years. CS type III is a phenotype in which major clinical features associated with CS only become apparent after age two years; growth and/or cognition exceeds the expectations for CS type I. COFS syndrome is characterized by very severe prenatal developmental anomalies (arthrogryposis and microphthalmia).</div>
|
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<div class="spaceAbove nowrap">See: <a href="/medgen/155488">Condition Record</a></div></div>
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||
<div class="divPopper rprt" id="rdis_199606"><div><strong>Classic homocystinuria</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>199606</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0751202</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Homocystinuria caused by cystathionine ß-synthase (CBS) deficiency is characterized by involvement of the eye (ectopia lentis and/or severe myopia), skeletal system (excessive height, long limbs, scolioisis, and pectus excavatum), vascular system (thromboembolism), and CNS (developmental delay/intellectual disability). All four ? or only one ? of the systems can be involved; expressivity is variable for all of the clinical signs. It is not unusual for a previously asymptomatic individual to present in adult years with only a thromboembolic event that is often cerebrovascular. Two phenotypic variants are recognized, B6-responsive homocystinuria and B6-non-responsive homocystinuria. B6-responsive homocystinuria is usually milder than the non-responsive variant. Thromboembolism is the major cause of early death and morbidity. IQ in individuals with untreated homocystinuria ranges widely, from 10 to 138. In B6-responsive individuals the mean IQ is 79 versus 57 for those who are B6-non-responsive. Other features that may occur include: seizures, psychiatric problems, extrapyramidal signs (e.g., dystonia), hypopigmentation of the skin and hair, malar flush, livedo reticularis, and pancreatitis.</div>
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||
<div class="spaceAbove nowrap">See: <a href="/medgen/199606">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_167103"><div><strong>Myhre syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>167103</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0796081</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Myhre syndrome is a multisystem progressive connective tissue disorder that often results in significant complications. The highly distinctive (and often severe) findings of joint stiffness, restrictive lung and cardiovascular disease, progressive and proliferative fibrosis, and thickening of the skin usually occur spontaneously. Some proliferation such as abnormal scarring or adhesions may follow trauma, invasive medical procedures, or surgery. Effusions of the heart, airways, lungs, uterus, and peritoneum may occur and can progress to fibrosis. Most affected individuals have characteristic facial features (short palpebral fissures, deeply set eyes, maxillary underdevelopment, short philtrum, thin vermilion of the upper lip, narrow mouth, and prognathism) and developmental delay / cognitive disability, typically in the mild-to-moderate range. Neurobehavioral issues may include autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), and/or anxiety. Although immunoglobulin (Ig) G and IgA deficiency are rare, affected individuals can experience recurrent infections (including otitis media, sinusitis, mastoiditis, or croup). Hearing loss can progress over time. Growth may be impaired in early life. Most adolescents develop obesity. Eye findings can include refractive errors, astigmatism, corectopia, and optic nerve anomalies. Gastrointestinal (GI) issues may include gastroesophageal reflux disease, constipation, and encopresis. Less commonly, stenosis of the GI tract, Hirschsprung disease, and/or metabolic dysfunction-associated liver disease may be observed.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/167103">Condition Record</a></div></div>
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||
<div class="divPopper rprt" id="rdis_226997"><div><strong>Congenital fascial dystrophy</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>226997</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1302740</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Congenital Abnormality</dd></dl></div></div></div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/226997">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_331978"><div><strong>Leri pleonosteosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>331978</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1835450</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Leri pleonosteosis is an autosomal dominant skeletal disorder characterized by flexion contractures of the interphalangeal joints, limited movement of multiple joints, and short, broad metacarpals, metatarsals, and phalanges. Additional features may include chronic joint pain, short stature, bony overgrowths, spinal cord compression, scleroderma-like skin changes, and blepharophimosis. The clinical features overlap with several other musculoskeletal conditions, including Myhre syndrome (MYHRS; 139210) and geleophysic dysplasia (GPHYSD1; 231050) (summary by Banka et al., 2015).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/331978">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_324580"><div><strong>Spondyloepiphyseal dysplasia with metatarsal shortening</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>324580</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1836683</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Congenital Abnormality</dd></dl></div></div></div>
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||
<div class="spaceAbove">Czech dysplasia is an autosomal dominant skeletal dysplasia characterized by early-onset, progressive pseudorheumatoid arthritis, platyspondyly, and short third and fourth toes (Marik et al., 2004; Kozlowski et al., 2004).</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/324580">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_435914"><div><strong>Mucolipidosis type II</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>435914</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2673377</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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||
<div class="spaceAbove">GNPTAB-related disorders comprise the phenotypes mucolipidosis II (ML II) and mucolipidosis IIIa/ß (ML IIIa/ß), and phenotypes intermediate between ML II and ML IIIa/ß. ML II is evident at birth and slowly progressive; death most often occurs in early childhood. Orthopedic abnormalities present at birth may include thoracic deformity, kyphosis, clubfeet, deformed long bones, and/or dislocation of the hip(s). Growth often ceases in the second year of life; contractures develop in all large joints. The skin is thickened, facial features are coarse, and gingiva are hypertrophic. All children have cardiac involvement, most commonly thickening and insufficiency of the mitral valve and, less frequently, the aortic valve. Progressive mucosal thickening narrows the airways, and gradual stiffening of the thoracic cage contributes to respiratory insufficiency, the most common cause of death. ML IIIa/ß becomes evident at about age three years with slow growth rate and short stature; joint stiffness and pain initially in the shoulders, hips, and fingers; gradual mild coarsening of facial features; and normal to mildly impaired cognitive development. Pain from osteoporosis becomes more severe during adolescence. Cardiorespiratory complications (restrictive lung disease, thickening and insufficiency of the mitral and aortic valves, left and/or right ventricular hypertrophy) are common causes of death, typically in early to middle adulthood. Phenotypes intermediate between ML II and ML IIIa/ß are characterized by physical growth in infancy that resembles that of ML II and neuromotor and speech development that resemble that of ML IIIa/ß.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/435914">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_481684"><div><strong>Geleophysic dysplasia 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>481684</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3280054</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Geleophysic dysplasia, a progressive condition resembling a lysosomal storage disorder, is characterized by short stature, short hands and feet, progressive joint limitation and contractures, distinctive facial features, progressive cardiac valvular disease, and thickened skin. Intellect is normal. The characteristic clinical findings are likely to be present in the first year of life. Cardiac, airway, and pulmonary involvement result in death before age five years in approximately 33% of individuals.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/481684">Condition Record</a></div></div>
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||
<div class="divPopper rprt" id="rdis_762085"><div><strong>Spondyloepiphyseal dysplasia tarda, X-linked</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>762085</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3541456</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Congenital Abnormality</dd></dl></div></div></div>
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<div class="spaceAbove">X-linked spondyloepiphyseal dysplasia tarda is a condition that impairs bone growth and occurs almost exclusively in males. The name of the condition indicates that it affects the bones of the spine (spondylo-) and the ends of long bones (epiphyses) in the arms and legs. "Tarda" indicates that signs and symptoms of this condition are not present at birth, but appear later in childhood, typically between ages 6 and 10.\n\nMales with X-linked spondyloepiphyseal dysplasia tarda have skeletal abnormalities and short stature. Affected boys grow steadily until late childhood, when their growth slows. Their adult height ranges from 4 feet 6 inches (137 cm) to 5 feet 4 inches (163 cm). Impaired growth of the spinal bones (vertebrae) primarily causes the short stature. Spinal abnormalities include flattened vertebrae (platyspondyly) with hump-shaped bulges, progressive thinning of the discs between vertebrae, and an abnormal curvature of the spine (scoliosis or kyphosis). These spinal problems also cause back pain in people with this condition. Individuals with X-linked spondyloepiphyseal dysplasia tarda have a short torso and neck, and their arms are disproportionately long compared to their height.\n\nOther skeletal features of X-linked spondyloepiphyseal dysplasia tarda include an abnormality of the hip joint that causes the upper leg bones to turn inward (coxa vara); multiple abnormalities of the epiphyses, including a short upper end of the thigh bone (femoral neck); and a broad, barrel-shaped chest. A painful joint condition called osteoarthritis that typically occurs in older adults often develops in early adulthood in people with X-linked spondyloepiphyseal dysplasia tarda and worsens over time, most often affecting the hips, knees, and shoulders.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/762085">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_854757"><div><strong>Smith-McCort dysplasia 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>854757</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3888088</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Any Smith-McCort dysplasia in which the cause of the disease is a mutation in the DYM gene.</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/854757">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_1641972"><div><strong>Hypertrophic osteoarthropathy, primary, autosomal recessive, 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1641972</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4551679</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">Autosomal recessive primary hypertrophic osteoarthropathy-1 (PHOAR1) is a rare familial disorder characterized by digital clubbing, osteoarthropathy, and acroosteolysis, with variable features of pachydermia, delayed closure of the fontanels, and congenital heart disease (summary by Uppal et al., 2008; Radhakrishnan et al., 2020). Secondary hypertrophic osteoarthropathy, or pulmonary hypertrophic osteoarthropathy, is a different disorder characterized by digital clubbing secondary to acquired diseases, most commonly intrathoracic neoplasm (Uppal et al., 2008). Touraine et al. (1935) recognized pachydermoperiostosis as a familial disorder with 3 clinical presentations or forms: a complete form characterized by periostosis and pachydermia; an incomplete form with bone changes but without pachydermia; and a 'forme fruste' with pachydermia and minimal skeletal changes. Genetic Heterogeneity Autosomal recessive primary hypertrophic osteoarthropathy-2-enteropathy syndrome (PHOAR2E; 614441) is caused by mutation in the SLCO2A1 gene (601460) on chromosome 3q22. Families with an autosomal dominant form of primary hypertrophic osteoarthropathy, in which patients may also experience gastrointestinal symptoms, have been reported (PHOAD; 167100).</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/1641972">Condition Record</a></div></div>
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<div class="divPopper rprt" id="rdis_1794223"><div><strong>Rhizomelic dysplasia, Ain-Naz type</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1794223</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5562013</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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<div class="spaceAbove">The Ain-Naz type of rhizomelic dysplasia (RHZDAN) is characterized by severe short stature with marked rhizomelic shortening of the limbs, platyspondyly, and large hands and feet relative to height (Ain et al., 2021).</div>
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<div class="spaceAbove nowrap">See: <a href="/medgen/1794223">Condition Record</a></div></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_199606" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Classic homocystinuria</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_155488" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cockayne syndrome type 1</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_155487" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cockayne syndrome type 2</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_226997" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Congenital fascial dystrophy</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_120527" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Dyggve-Melchior-Clausen syndrome</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (19)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_481684" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Geleophysic dysplasia 2</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1641972" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hypertrophic osteoarthropathy, primary, autosomal recessive, 1</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_75559" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Kniest dysplasia</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_140930" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Kyphomelic dysplasia</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_331978" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Leri pleonosteosis</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_435914" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Mucolipidosis type II</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_43108" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Mucopolysaccharidosis type 7</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_167103" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Myhre syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_10988" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Pseudo-Hurler polydystrophy</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1794223" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Rhizomelic dysplasia, Ain-Naz type</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_98145" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Rolland-Debuqois syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_854757" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Smith-McCort dysplasia 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_762085" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Spondyloepiphyseal dysplasia tarda, X-linked</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_324580" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Spondyloepiphyseal dysplasia with metatarsal shortening</a></div></span></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34331696">A Systematic Review of the Clinical Use of Curcumin for the Treatment of Osteoarthritis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shokri-Mashhadi N,
|
||
Bagherniya M,
|
||
Askari G,
|
||
Sathyapalan T,
|
||
Sahebkar A</span><br />
|
||
<span class="medgenPMjournal">Adv Exp Med Biol</span>
|
||
2021;1291:265-282.
|
||
doi: 10.1007/978-3-030-56153-6_16.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34331696" target="_blank">34331696</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30648666">Evaluation of the Effectiveness of Hyaluronic Acid Injections in Treatment of Small Joint Osteoarthritis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Międzybłocka M,
|
||
Czarnecki P</span><br />
|
||
<span class="medgenPMjournal">Ortop Traumatol Rehabil</span>
|
||
2018 Oct 31;20(5):437-443.
|
||
doi: 10.5604/01.3001.0012.8391.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30648666" target="_blank">30648666</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22limitation%20of%20joint%20mobility%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (2)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34772852">Adhesive capsulitis: A review for clinicians.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ricci M</span><br />
|
||
<span class="medgenPMjournal">JAAPA</span>
|
||
2021 Dec 1;34(12):12-14.
|
||
doi: 10.1097/01.JAA.0000800236.81700.d4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34772852" target="_blank">34772852</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33252600">Physiotherapy in hypomobility of temporomandibular joints.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Byra J,
|
||
Kulesa-Mrowiecka M,
|
||
Pihut M</span><br />
|
||
<span class="medgenPMjournal">Folia Med Cracov</span>
|
||
2020 Sep 28;60(2):123-134.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33252600" target="_blank">33252600</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30486819">Effects of deep cervical flexor training on impaired physiological functions associated with chronic neck pain: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Blomgren J,
|
||
Strandell E,
|
||
Jull G,
|
||
Vikman I,
|
||
Röijezon U</span><br />
|
||
<span class="medgenPMjournal">BMC Musculoskelet Disord</span>
|
||
2018 Nov 28;19(1):415.
|
||
doi: 10.1186/s12891-018-2324-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30486819" target="_blank">30486819</a><a href="/pmc/articles/PMC6263552" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26642915">Acute effects of muscle stretching on physical performance, range of motion, and injury incidence in healthy active individuals: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Behm DG,
|
||
Blazevich AJ,
|
||
Kay AD,
|
||
McHugh M</span><br />
|
||
<span class="medgenPMjournal">Appl Physiol Nutr Metab</span>
|
||
2016 Jan;41(1):1-11.
|
||
Epub 2015 Dec 8
|
||
doi: 10.1139/apnm-2015-0235.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26642915" target="_blank">26642915</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21070485">Range of motion measurements: reference values and a database for comparison studies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Soucie JM,
|
||
Wang C,
|
||
Forsyth A,
|
||
Funk S,
|
||
Denny M,
|
||
Roach KE,
|
||
Boone D;
|
||
Hemophilia Treatment Center Network</span><br />
|
||
<span class="medgenPMjournal">Haemophilia</span>
|
||
2011 May;17(3):500-7.
|
||
Epub 2010 Nov 11
|
||
doi: 10.1111/j.1365-2516.2010.02399.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21070485" target="_blank">21070485</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Limitation%20of%20joint%20mobility%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5229)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34772852">Adhesive capsulitis: A review for clinicians.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ricci M</span><br />
|
||
<span class="medgenPMjournal">JAAPA</span>
|
||
2021 Dec 1;34(12):12-14.
|
||
doi: 10.1097/01.JAA.0000800236.81700.d4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34772852" target="_blank">34772852</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33252600">Physiotherapy in hypomobility of temporomandibular joints.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Byra J,
|
||
Kulesa-Mrowiecka M,
|
||
Pihut M</span><br />
|
||
<span class="medgenPMjournal">Folia Med Cracov</span>
|
||
2020 Sep 28;60(2):123-134.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33252600" target="_blank">33252600</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30204635">Shoulder Instability in the Overhead Athlete.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">DeFroda SF,
|
||
Goyal D,
|
||
Patel N,
|
||
Gupta N,
|
||
Mulcahey MK</span><br />
|
||
<span class="medgenPMjournal">Curr Sports Med Rep</span>
|
||
2018 Sep;17(9):308-314.
|
||
doi: 10.1249/JSR.0000000000000517.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30204635" target="_blank">30204635</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27886840">Elbow Dislocations in Contact Sports.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Morris MS,
|
||
Ozer K</span><br />
|
||
<span class="medgenPMjournal">Hand Clin</span>
|
||
2017 Feb;33(1):63-72.
|
||
doi: 10.1016/j.hcl.2016.08.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27886840" target="_blank">27886840</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24388681">Surgical and therapy update on the management of Dupuytren's disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sweet S,
|
||
Blackmore S</span><br />
|
||
<span class="medgenPMjournal">J Hand Ther</span>
|
||
2014 Apr-Jun;27(2):77-83; quiz 84.
|
||
Epub 2013 Nov 5
|
||
doi: 10.1016/j.jht.2013.10.006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24388681" target="_blank">24388681</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Limitation%20of%20joint%20mobility%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2259)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38704572">Effect of extracorporeal shockwave therapy for rotator cuff tendinopathy: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Xue X,
|
||
Song Q,
|
||
Yang X,
|
||
Kuati A,
|
||
Fu H,
|
||
Liu Y,
|
||
Cui G</span><br />
|
||
<span class="medgenPMjournal">BMC Musculoskelet Disord</span>
|
||
2024 May 4;25(1):357.
|
||
doi: 10.1186/s12891-024-07445-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38704572" target="_blank">38704572</a><a href="/pmc/articles/PMC11069249" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33185587">The efficacy of physiotherapy interventions in the treatment of adhesive capsulitis: A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nakandala P,
|
||
Nanayakkara I,
|
||
Wadugodapitiya S,
|
||
Gawarammana I</span><br />
|
||
<span class="medgenPMjournal">J Back Musculoskelet Rehabil</span>
|
||
2021;34(2):195-205.
|
||
doi: 10.3233/BMR-200186.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33185587" target="_blank">33185587</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27634093">Kinesio taping for chronic low back pain: A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nelson NL</span><br />
|
||
<span class="medgenPMjournal">J Bodyw Mov Ther</span>
|
||
2016 Jul;20(3):672-81.
|
||
Epub 2016 Apr 27
|
||
doi: 10.1016/j.jbmt.2016.04.018.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27634093" target="_blank">27634093</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26642915">Acute effects of muscle stretching on physical performance, range of motion, and injury incidence in healthy active individuals: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Behm DG,
|
||
Blazevich AJ,
|
||
Kay AD,
|
||
McHugh M</span><br />
|
||
<span class="medgenPMjournal">Appl Physiol Nutr Metab</span>
|
||
2016 Jan;41(1):1-11.
|
||
Epub 2015 Dec 8
|
||
doi: 10.1139/apnm-2015-0235.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26642915" target="_blank">26642915</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23152232">Rehabilitation for ankle fractures in adults.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lin CW,
|
||
Donkers NA,
|
||
Refshauge KM,
|
||
Beckenkamp PR,
|
||
Khera K,
|
||
Moseley AM</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2012 Nov 14;11:CD005595.
|
||
doi: 10.1002/14651858.CD005595.pub3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23152232" target="_blank">23152232</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Limitation%20of%20joint%20mobility%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2482)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35292045">Legg-Calvé-Perthes disease overview.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rodríguez-Olivas AO,
|
||
Hernández-Zamora E,
|
||
Reyes-Maldonado E</span><br />
|
||
<span class="medgenPMjournal">Orphanet J Rare Dis</span>
|
||
2022 Mar 15;17(1):125.
|
||
doi: 10.1186/s13023-022-02275-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35292045" target="_blank">35292045</a><a href="/pmc/articles/PMC8922924" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28476110">Restriction in lateral bending range of motion, lumbar lordosis, and hamstring flexibility predicts the development of low back pain: a systematic review of prospective cohort studies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sadler SG,
|
||
Spink MJ,
|
||
Ho A,
|
||
De Jonge XJ,
|
||
Chuter VH</span><br />
|
||
<span class="medgenPMjournal">BMC Musculoskelet Disord</span>
|
||
2017 May 5;18(1):179.
|
||
doi: 10.1186/s12891-017-1534-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28476110" target="_blank">28476110</a><a href="/pmc/articles/PMC5418732" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25856757">Rehabilitation following total hip arthroplasty evaluation over short follow-up time: randomized clinical trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Umpierres CS,
|
||
Ribeiro TA,
|
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Marchisio ÂE,
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Galvão L,
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Borges ÍN,
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Macedo CA,
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<span class="medgenPMjournal">J Rehabil Res Dev</span>
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2014;51(10):1567-78.
|
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doi: 10.1682/JRRD.2014.05.0132.
|
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<span class="bold">PMID: </span><a href="/pubmed/25856757" target="_blank">25856757</a></div>
|
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|
||
<div class="nl"><a target="_blank" href="/pubmed/22014477">Effect of two rehabilitation protocols on range of motion and healing rates after arthroscopic rotator cuff repair: aggressive versus limited early passive exercises.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lee BG,
|
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Cho NS,
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Rhee YG</span><br />
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<span class="medgenPMjournal">Arthroscopy</span>
|
||
2012 Jan;28(1):34-42.
|
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Epub 2011 Oct 20
|
||
doi: 10.1016/j.arthro.2011.07.012.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22014477" target="_blank">22014477</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18416885">24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Clark KL,
|
||
Sebastianelli W,
|
||
Flechsenhar KR,
|
||
Aukermann DF,
|
||
Meza F,
|
||
Millard RL,
|
||
Deitch JR,
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||
Sherbondy PS,
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||
Albert A</span><br />
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<span class="medgenPMjournal">Curr Med Res Opin</span>
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||
2008 May;24(5):1485-96.
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Epub 2008 Apr 15
|
||
doi: 10.1185/030079908x291967.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18416885" target="_blank">18416885</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Limitation%20of%20joint%20mobility%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2252)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35803550">The efficacy of graded motor imagery in post-traumatic stiffness of elbow: a randomized controlled trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Birinci T,
|
||
Kaya Mutlu E,
|
||
Altun S</span><br />
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||
<span class="medgenPMjournal">J Shoulder Elbow Surg</span>
|
||
2022 Oct;31(10):2147-2156.
|
||
Epub 2022 Jul 5
|
||
doi: 10.1016/j.jse.2022.05.031.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35803550" target="_blank">35803550</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31924519">A randomized single-blinded trial of early rehabilitation versus immobilization after reverse total shoulder arthroplasty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hagen MS,
|
||
Allahabadi S,
|
||
Zhang AL,
|
||
Feeley BT,
|
||
Grace T,
|
||
Ma CB</span><br />
|
||
<span class="medgenPMjournal">J Shoulder Elbow Surg</span>
|
||
2020 Mar;29(3):442-450.
|
||
Epub 2020 Jan 7
|
||
doi: 10.1016/j.jse.2019.10.005.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31924519" target="_blank">31924519</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28476110">Restriction in lateral bending range of motion, lumbar lordosis, and hamstring flexibility predicts the development of low back pain: a systematic review of prospective cohort studies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sadler SG,
|
||
Spink MJ,
|
||
Ho A,
|
||
De Jonge XJ,
|
||
Chuter VH</span><br />
|
||
<span class="medgenPMjournal">BMC Musculoskelet Disord</span>
|
||
2017 May 5;18(1):179.
|
||
doi: 10.1186/s12891-017-1534-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28476110" target="_blank">28476110</a><a href="/pmc/articles/PMC5418732" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23980032">The efficacy of manual joint mobilisation/manipulation in treatment of lateral ankle sprains: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Loudon JK,
|
||
Reiman MP,
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Sylvain J</span><br />
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||
<span class="medgenPMjournal">Br J Sports Med</span>
|
||
2014 Mar;48(5):365-70.
|
||
Epub 2013 Aug 26
|
||
doi: 10.1136/bjsports-2013-092763.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23980032" target="_blank">23980032</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23914912">Therapeutic interventions for increasing ankle dorsiflexion after ankle sprain: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Terada M,
|
||
Pietrosimone BG,
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||
Gribble PA</span><br />
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||
<span class="medgenPMjournal">J Athl Train</span>
|
||
2013 Sep-Oct;48(5):696-709.
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||
Epub 2013 Aug 5
|
||
doi: 10.4085/1062-6050-48.4.11.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23914912" target="_blank">23914912</a><a href="/pmc/articles/PMC3784372" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Limitation%20of%20joint%20mobility%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3886)</a></div></div>
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|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/33185587">The efficacy of physiotherapy interventions in the treatment of adhesive capsulitis: A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nakandala P,
|
||
Nanayakkara I,
|
||
Wadugodapitiya S,
|
||
Gawarammana I</span><br />
|
||
<span class="medgenPMjournal">J Back Musculoskelet Rehabil</span>
|
||
2021;34(2):195-205.
|
||
doi: 10.3233/BMR-200186.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33185587" target="_blank">33185587</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28027039">Effectiveness of Occupational Therapy Interventions for Musculoskeletal Shoulder Conditions: A Systematic Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Marik TL,
|
||
Roll SC</span><br />
|
||
<span class="medgenPMjournal">Am J Occup Ther</span>
|
||
2017 Jan/Feb;71(1):7101180020p1-7101180020p11.
|
||
doi: 10.5014/ajot.2017.023127.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28027039" target="_blank">28027039</a><a href="/pmc/articles/PMC5182015" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26642915">Acute effects of muscle stretching on physical performance, range of motion, and injury incidence in healthy active individuals: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Behm DG,
|
||
Blazevich AJ,
|
||
Kay AD,
|
||
McHugh M</span><br />
|
||
<span class="medgenPMjournal">Appl Physiol Nutr Metab</span>
|
||
2016 Jan;41(1):1-11.
|
||
Epub 2015 Dec 8
|
||
doi: 10.1139/apnm-2015-0235.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26642915" target="_blank">26642915</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26294683">Effectiveness of Manual Therapy and Therapeutic Exercise for Temporomandibular Disorders: Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Armijo-Olivo S,
|
||
Pitance L,
|
||
Singh V,
|
||
Neto F,
|
||
Thie N,
|
||
Michelotti A</span><br />
|
||
<span class="medgenPMjournal">Phys Ther</span>
|
||
2016 Jan;96(1):9-25.
|
||
Epub 2015 Aug 20
|
||
doi: 10.2522/ptj.20140548.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26294683" target="_blank">26294683</a><a href="/pmc/articles/PMC4706597" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25157702">Manual therapy and exercise for adhesive capsulitis (frozen shoulder).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Page MJ,
|
||
Green S,
|
||
Kramer S,
|
||
Johnston RV,
|
||
McBain B,
|
||
Chau M,
|
||
Buchbinder R</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2014 Aug 26;2014(8):CD011275.
|
||
doi: 10.1002/14651858.CD011275.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25157702" target="_blank">25157702</a><a href="/pmc/articles/PMC10882424" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Limitation%20of%20joint%20mobility%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (402)</a></div></div>
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|
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|
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C1857108%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (33)</a></li>
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<li><a href="/gtr/tests?term=C1857108%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (33)</a></li>
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<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C1857108%5bDISCUI%5d" target="_blank">See all (33)</a></total></li>
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Limitation%20of%20joint%20mobility" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22limitation%20of%20joint%20mobility%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Limitation%20of%20joint%20mobility%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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<a href="/pubmed?term=Limitation%20of%20joint%20mobility%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=2&linkpostotal=2" target="_blank">Reviews in PubMed</a>
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<h3>Related information</h3>
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<a href="https://www.google.com/maps/place/8600+Rockville+Pike,+Bethesda,+MD+20894/@38.9959508,-77.101021,17z/data=!3m1!4b1!4m5!3m4!1s0x89b7c95e25765ddb:0x19156f88b27635b8!8m2!3d38.9959508!4d-77.0988323" class="text-white" target="_blank" rel="noopener noreferrer">8600 Rockville Pike<br />
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Bethesda, MD 20894</a></p>
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<p><a href="https://www.nlm.nih.gov/web_policies.html" class="text-white">Web Policies</a><br />
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<p><a class="supportLink text-white" href="https://support.nlm.nih.gov/">Help</a><br />
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