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<meta name="keywords" content="C1849538, delayed deciduous tooth eruption, delayed eruption of baby teeth, delayed eruption of deciduous teeth, delayed eruption of milk teeth, delayed eruption of primary teeth, delayed primary teeth eruption, finding, late eruption of baby teeth, late eruption of milk teeth, late eruption of primary teeth, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Delayed tooth eruption affecting the primary dentition." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Delayed eruption of primary teeth</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>341477</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1849538</a></dd><dt><span class="dotprefix"></span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
<td>Delayed deciduous tooth eruption; Delayed eruption of deciduous teeth; Delayed primary teeth eruption</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0000680">HP:0000680</a></td></tr>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">Delayed tooth eruption affecting the primary dentition. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Delayed eruption of primary teeth</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/871375" ref="tree=MeSH" title="MedGen record for Abnormality of the face">Abnormality of the face</a></span><ul><li><span class="TLline"><a href="/medgen/6447" ref="tree=MeSH" title="MedGen record for Abnormality of the mouth">Abnormality of the mouth</a></span><ul><li><span class="TLline"><a href="/medgen/1645271" ref="tree=MeSH" title="MedGen record for Abnormal oral morphology">Abnormal oral morphology</a></span><ul><li><span class="TLline"><a href="/medgen/871391" ref="tree=MeSH" title="MedGen record for Abnormal oral cavity morphology">Abnormal oral cavity morphology</a></span><ul><li><span class="TLline"><a href="/medgen/78084" ref="tree=MeSH" title="MedGen record for Abnormality of the dentition">Abnormality of the dentition</a></span><ul><li><span class="TLline"><a href="/medgen/867237" ref="tree=MeSH" title="MedGen record for Abnormality of primary teeth">Abnormality of primary teeth</a></span><ul><li><span class="matched_ds">Delayed eruption of primary teeth</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln clinfeat">
<div class="divPopper rprt" id="rdis_3486"><div><strong>Cleidocranial dysostosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>3486</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0008928</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Cleidocranial dysplasia (CCD) spectrum disorder is a skeletal dysplasia that represents a clinical continuum ranging from classic CCD (triad of delayed closure of the cranial sutures, hypoplastic or aplastic clavicles, and dental abnormalities), to mild CCD, to isolated dental anomalies without other skeletal features. Individuals with classic CCD spectrum disorder typically have abnormally large, wide-open fontanelles at birth that may remain open throughout life. Clavicular hypoplasia can result in narrow, sloping shoulders that can be opposed at the midline. Moderate short stature may be observed, with most affected individuals being shorter than their unaffected sibs. Dental anomalies may include delayed eruption of secondary dentition, failure to shed the primary teeth, and supernumerary teeth. Individuals with CCD spectrum disorder are at increased risk of developing recurrent sinus infections, recurrent ear infections leading to conductive hearing loss, and upper airway obstruction. Intelligence is typically normal.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/3486">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_116061"><div><strong>Pyknodysostosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>116061</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0238402</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Pycnodysostosis is characterized by short-limbed short stature, typical facial appearance (convex nasal ridge and small jaw with obtuse mandibular angle), osteosclerosis with increased bone fragility, acroosteolysis of the distal phalanges, delayed closure of the cranial sutures, and dysplasia of the clavicle. In affected individuals, the facial features become more prominent with age, likely due to progressive acroosteolysis of the facial bones, but can usually be appreciated from early childhood, particularly the small jaw and convex nasal ridge. Additional features include dental and nail anomalies. Intelligence is typically normal with mild psychomotor difficulties reported in some individuals.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/116061">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_155487"><div><strong>Cockayne syndrome type 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>155487</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0751038</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Cockayne syndrome (referred to as CS in this GeneReview) spans a continuous phenotypic spectrum that includes CS type I, the "classic" or "moderate" form; CS type II, a more severe form with symptoms present at birth (this form overlaps with cerebrooculofacioskeletal [COFS] syndrome); CS type III, a milder and later-onset form; and COFS syndrome, a fetal form of CS. CS type I is characterized by normal prenatal growth with the onset of growth and developmental abnormalities in the first two years. By the time the disease has become fully manifest, height, weight, and head circumference are far below the fifth percentile. Progressive impairment of vision, hearing, and central and peripheral nervous system function leads to severe disability; death typically occurs in the first or second decade. CS type II is characterized by growth failure at birth, with little or no postnatal neurologic development. Congenital cataracts or other structural anomalies of the eye may be present. Affected children have early postnatal contractures of the spine (kyphosis, scoliosis) and joints. Death usually occurs by age five years. CS type III is a phenotype in which major clinical features associated with CS only become apparent after age two years; growth and/or cognition exceeds the expectations for CS type I. COFS syndrome is characterized by very severe prenatal developmental anomalies (arthrogryposis and microphthalmia).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/155487">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_155488"><div><strong>Cockayne syndrome type 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>155488</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0751039</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Cockayne syndrome (referred to as CS in this GeneReview) spans a continuous phenotypic spectrum that includes CS type I, the "classic" or "moderate" form; CS type II, a more severe form with symptoms present at birth (this form overlaps with cerebrooculofacioskeletal [COFS] syndrome); CS type III, a milder and later-onset form; and COFS syndrome, a fetal form of CS. CS type I is characterized by normal prenatal growth with the onset of growth and developmental abnormalities in the first two years. By the time the disease has become fully manifest, height, weight, and head circumference are far below the fifth percentile. Progressive impairment of vision, hearing, and central and peripheral nervous system function leads to severe disability; death typically occurs in the first or second decade. CS type II is characterized by growth failure at birth, with little or no postnatal neurologic development. Congenital cataracts or other structural anomalies of the eye may be present. Affected children have early postnatal contractures of the spine (kyphosis, scoliosis) and joints. Death usually occurs by age five years. CS type III is a phenotype in which major clinical features associated with CS only become apparent after age two years; growth and/or cognition exceeds the expectations for CS type I. COFS syndrome is characterized by very severe prenatal developmental anomalies (arthrogryposis and microphthalmia).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/155488">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_163222"><div><strong>Oculodental syndrome, Rutherfurd type</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>163222</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0796140</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Oculodental syndrome, Rutherfurd type is a rare genetic disorder that is primarily characterized by the classical triad of gingival fibromatosis, non-eruption of tooth and corneal dystrophy (bilateral corneal vascularization and opacity). Abnormally shaped teeth have also been reported. The syndrome is transmitted as an autosomal dominant trait.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/163222">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_323030"><div><strong>Emanuel syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>323030</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1836929</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Emanuel syndrome is characterized by pre- and postnatal growth deficiency, microcephaly, hypotonia, severe developmental delays, ear anomalies, preauricular tags or pits, cleft or high-arched palate, congenital heart defects, kidney abnormalities, and genital abnormalities in males.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/323030">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_338945"><div><strong>Craniometaphyseal dysplasia, autosomal dominant</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>338945</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1852502</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Autosomal dominant craniometaphyseal dysplasia (designated AD-CMD in this review) is characterized by progressive diffuse hyperostosis of cranial bones evident clinically as wide nasal bridge, paranasal bossing, widely spaced eyes with an increase in bizygomatic width, and prominent mandible. Development of dentition may be delayed and teeth may fail to erupt as a result of hyperostosis and sclerosis of alveolar bone. Progressive thickening of craniofacial bones continues throughout life, often resulting in narrowing of the cranial foramina, including the foramen magnum. If untreated, compression of cranial nerves can lead to disabling conditions such as facial palsy, blindness, or deafness (conductive and/or sensorineural hearing loss). In individuals with typical uncomplicated AD-CMD life expectancy is normal; in those with severe AD-CMD life expectancy can be reduced as a result of compression of the foramen magnum.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/338945">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_898794"><div><strong>Mandibulofacial dysostosis with alopecia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>898794</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C4225349</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">A rare mandibulofacial dysostosis with the association with scalp alopecia and sparse eyebrows and eyelashes. Craniofacial dysmorphic features include zygomatic and mandibular dysplasia or hypoplasia, cleft palate, micrognathia, dental anomalies, auricular dysmorphism and eyelid anomalies among others. Patients may experience limited jaw mobility, glossoptosis, upper airway obstruction and conductive hearing loss.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/898794">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_906997"><div><strong>Linear skin defects with multiple congenital anomalies 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>906997</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C4225421</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Microphthalmia with linear skin defects (MLS) syndrome is characterized by unilateral or bilateral microphthalmia and/or anophthalmia and linear skin defects, usually involving the face and neck, which are present at birth and heal with age, leaving minimal residual scarring. Other findings can include a wide variety of other ocular abnormalities (e.g., corneal anomalies, orbital cysts, cataracts), central nervous system involvement (e.g., structural anomalies, developmental delay, infantile seizures), cardiac concerns (e.g., hypertrophic or oncocytic cardiomyopathy, atrial or ventricular septal defects, arrhythmias), short stature, diaphragmatic hernia, nail dystrophy, hearing impairment, and genitourinary malformations. Inter- and intrafamilial variability is described.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/906997">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1614787"><div><strong>Intellectual disability, autosomal dominant 54</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1614787</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C4540484</a></dd><dt><span class="dotprefix"></span></dt><dd>Mental or Behavioral Dysfunction</dd></dl></div></div></div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1614787">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1784907"><div><strong>Marbach-Rustad progeroid syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1784907</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C5543388</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Marbach-Rustad progeroid syndrome (MARUPS) is characterized by progeroid appearance with little subcutaneous fat and triangular facies, growth retardation with short stature, hypoplastic mandible crowded with unerupted supernumerary teeth, and cerebellar intention tremor. Psychomotor development is normal. Although features are reminiscent of Hutchinson-Gilford progeria syndrome (HGPS; 176670), MARUPS is less severe, with a relatively good prognosis. Two patients have been reported (Marbach et al., 2019).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1784907">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1824016"><div><strong>Cleidocranial dysplasia 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1824016</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C5774243</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Cleidocranial dysplasia-2 (CLCD2) is characterized by clavicular anomalies, ranging from unilateral 'clavicula bipartita' to bilateral clavicular aplasia, and dental anomalies, including delayed or absent eruption of deciduous teeth and supernumerary teeth. Skull abnormalities such as delayed closure of fontanels have been reported; other skeletal features include delayed bone age, short distal phalanges, and pseudoepiphyses of the metacarpals and/or metatarsals. Phenotypic variability, including intrafamilial, has been observed (Beyltjens et al., 2023).&#13; For a general phenotypic description and a discussion of genetic heterogeneity of cleidocranial dysplasia, see CLCD1 (119600).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1824016">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1824096"><div><strong>LADD syndrome 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1824096</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C5774323</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Lacrimoauriculodentodigital syndrome-1 (LADD1) is a multiple congenital anomaly disorder mainly affecting lacrimal glands and ducts, salivary glands and ducts, ears, teeth, and distal limb segments (summary by Rohmann et al., 2006).&#13; Genetic Heterogeneity of Lacrimoauriculodentodigital Syndrome&#13; LADD syndrome-2 (LADD2; 620192) is caused by mutation in the FGFR3 gene (134934) on chromosome 4p16, and LADD syndrome-3 (LADD3; 620193) is caused by mutation in the FGF10 gene, an FGFR ligand, on chromosome 5p12.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1824096">Condition Record</a></div></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_3486" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cleidocranial dysostosis</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1824016" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cleidocranial dysplasia 2</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_155488" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cockayne syndrome type 1</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_155487" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cockayne syndrome type 2</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_338945" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Craniometaphyseal dysplasia, autosomal dominant</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (13)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_323030" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Emanuel syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1614787" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Intellectual disability, autosomal dominant 54</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1824096" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">LADD syndrome 1</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_906997" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Linear skin defects with multiple congenital anomalies 3</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_898794" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Mandibulofacial dysostosis with alopecia</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1784907" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Marbach-Rustad progeroid syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_163222" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Oculodental syndrome, Rutherfurd type</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_116061" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Pyknodysostosis</a></div></span></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/32151309">Diagnosis, Management and Follow-Up of a Rare Regional Developmental Disorder: Segmental Odontomaxillary Dysplasia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Heggie C,
Gartshore L</span><br />
<span class="medgenPMjournal">J Dent Child (Chic)</span>
2020 Jan 15;87(1):39-43.
<span class="bold">PMID: </span><a href="/pubmed/32151309" target="_blank">32151309</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27725317">Timing of dental development in osteogenesis imperfecta patients with and without bisphosphonate treatment.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Vuorimies I,
Arponen H,
Valta H,
Tiesalo O,
Ekholm M,
Ranta H,
Evälahti M,
Mäkitie O,
Waltimo-Sirén J</span><br />
<span class="medgenPMjournal">Bone</span>
2017 Jan;94:29-33.
Epub 2016 Oct 7
doi: 10.1016/j.bone.2016.10.004.
<span class="bold">PMID: </span><a href="/pubmed/27725317" target="_blank">27725317</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23729457">Management of ankylosed primary molars with premolar successors: a systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tieu LD,
Walker SL,
Major MP,
Flores-Mir C</span><br />
<span class="medgenPMjournal">J Am Dent Assoc</span>
2013 Jun;144(6):602-11.
doi: 10.14219/jada.archive.2013.0171.
<span class="bold">PMID: </span><a href="/pubmed/23729457" target="_blank">23729457</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(delayed%20eruption%20of%20primary%20teeth)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (8)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/36907703">Interventions to facilitate the successful eruption of impacted maxillary incisor teeth due to the presence of a supernumerary: A systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Seehra J,
Mortaja K,
Wazwaz F,
Papageorgiou SN,
Newton JT,
Cobourne MT</span><br />
<span class="medgenPMjournal">Am J Orthod Dentofacial Orthop</span>
2023 May;163(5):594-608.
Epub 2023 Mar 11
doi: 10.1016/j.ajodo.2023.01.004.
<span class="bold">PMID: </span><a href="/pubmed/36907703" target="_blank">36907703</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36890742">Assessment of permanent teeth development in children with multiple persistent primary teeth.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Topal BG,
Tanrikulu A</span><br />
<span class="medgenPMjournal">J Clin Pediatr Dent</span>
2023 Mar;47(2):50-57.
Epub 2023 Mar 3
doi: 10.22514/jocpd.2023.011.
<span class="bold">PMID: </span><a href="/pubmed/36890742" target="_blank">36890742</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37005999">Influence of gestational age on eruption of primary teeth in Indian children - A prospective longitudinal study.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Mysore ID,
Nandlal B,
Narayanappa D</span><br />
<span class="medgenPMjournal">Indian J Dent Res</span>
2022 Oct-Dec;33(4):373-377.
doi: 10.4103/ijdr.ijdr_56_22.
<span class="bold">PMID: </span><a href="/pubmed/37005999" target="_blank">37005999</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34970995">Orthodontic treatment for crowded teeth in children.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Turner S,
Harrison JE,
Sharif FN,
Owens D,
Millett DT</span><br />
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
2021 Dec 31;12(12):CD003453.
doi: 10.1002/14651858.CD003453.pub2.
<span class="bold">PMID: </span><a href="/pubmed/34970995" target="_blank">34970995</a><a href="/pmc/articles/PMC8786262" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29402820">Primary Fused Teeth and Findings in Permanent Dentition.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">ıkel H,
İbiş S,
Şen Tunç E</span><br />
<span class="medgenPMjournal">Med Princ Pract</span>
2018;27(2):129-132.
Epub 2018 Feb 1
doi: 10.1159/000487322.
<span class="bold">PMID: </span><a href="/pubmed/29402820" target="_blank">29402820</a><a href="/pmc/articles/PMC5968246" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Delayed%20eruption%20of%20primary%20teeth%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (130)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/40004475">Syndromic and Non-Syndromic Primary Failure of Tooth Eruption: A Genetic Overview.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Modafferi C,
Tabolacci E,
Grippaudo C,
Chiurazzi P</span><br />
<span class="medgenPMjournal">Genes (Basel)</span>
2025 Jan 24;16(2)
doi: 10.3390/genes16020147.
<span class="bold">PMID: </span><a href="/pubmed/40004475" target="_blank">40004475</a><a href="/pmc/articles/PMC11855040" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/38128337">Global variations in eruption chronology of primary teeth: A systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Muthu MS,
Vandana S,
Akila G,
Anusha M,
Kandaswamy D,
Aswath Narayanan MB</span><br />
<span class="medgenPMjournal">Arch Oral Biol</span>
2024 Feb;158:105857.
Epub 2023 Dec 6
doi: 10.1016/j.archoralbio.2023.105857.
<span class="bold">PMID: </span><a href="/pubmed/38128337" target="_blank">38128337</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35231627">Development of dentition: From initiation to occlusion and related diseases.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kurosaka H,
Itoh S,
Morita C,
Tsujimoto T,
Murata Y,
Inubushi T,
Yamashiro T</span><br />
<span class="medgenPMjournal">J Oral Biosci</span>
2022 Jun;64(2):159-164.
Epub 2022 Feb 26
doi: 10.1016/j.job.2022.02.005.
<span class="bold">PMID: </span><a href="/pubmed/35231627" target="_blank">35231627</a></div>
<div class="nl"><a target="_blank" href="/pubmed/14969379">Crouzonodermoskeletal syndrome.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Jeftha A,
Stephen L,
Morkel JA,
Beighton P</span><br />
<span class="medgenPMjournal">J Clin Pediatr Dent</span>
2004 Winter;28(2):173-6.
doi: 10.17796/jcpd.28.2.72m01l5g50448548.
<span class="bold">PMID: </span><a href="/pubmed/14969379" target="_blank">14969379</a></div>
<div class="nl"><a target="_blank" href="/pubmed/6947185">Passive delayed eruption of the primary dentition secondary to Dilantin administration. Report of a case.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Reich DR,
Bernbaum J,
Moskowitz WB</span><br />
<span class="medgenPMjournal">Oral Surg Oral Med Oral Pathol</span>
1981 Dec;52(6):599-601.
doi: 10.1016/0030-4220(81)90076-1.
<span class="bold">PMID: </span><a href="/pubmed/6947185" target="_blank">6947185</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Delayed%20eruption%20of%20primary%20teeth%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (100)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/36907703">Interventions to facilitate the successful eruption of impacted maxillary incisor teeth due to the presence of a supernumerary: A systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Seehra J,
Mortaja K,
Wazwaz F,
Papageorgiou SN,
Newton JT,
Cobourne MT</span><br />
<span class="medgenPMjournal">Am J Orthod Dentofacial Orthop</span>
2023 May;163(5):594-608.
Epub 2023 Mar 11
doi: 10.1016/j.ajodo.2023.01.004.
<span class="bold">PMID: </span><a href="/pubmed/36907703" target="_blank">36907703</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37005999">Influence of gestational age on eruption of primary teeth in Indian children - A prospective longitudinal study.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Mysore ID,
Nandlal B,
Narayanappa D</span><br />
<span class="medgenPMjournal">Indian J Dent Res</span>
2022 Oct-Dec;33(4):373-377.
doi: 10.4103/ijdr.ijdr_56_22.
<span class="bold">PMID: </span><a href="/pubmed/37005999" target="_blank">37005999</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34970995">Orthodontic treatment for crowded teeth in children.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Turner S,
Harrison JE,
Sharif FN,
Owens D,
Millett DT</span><br />
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
2021 Dec 31;12(12):CD003453.
doi: 10.1002/14651858.CD003453.pub2.
<span class="bold">PMID: </span><a href="/pubmed/34970995" target="_blank">34970995</a><a href="/pmc/articles/PMC8786262" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29575874">Influence of growth hormone therapy on selected dental and skeletal system parameters.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Partyka M,
Chałas R,
Dunin-Wilczyńska I,
Drohomyretska M,
Klatka M</span><br />
<span class="medgenPMjournal">Ann Agric Environ Med</span>
2018 Mar 14;25(1):60-65.
Epub 2017 Feb 11
doi: 10.5604/12321966.1233573.
<span class="bold">PMID: </span><a href="/pubmed/29575874" target="_blank">29575874</a></div>
<div class="nl"><a target="_blank" href="/pubmed/6947185">Passive delayed eruption of the primary dentition secondary to Dilantin administration. Report of a case.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Reich DR,
Bernbaum J,
Moskowitz WB</span><br />
<span class="medgenPMjournal">Oral Surg Oral Med Oral Pathol</span>
1981 Dec;52(6):599-601.
doi: 10.1016/0030-4220(81)90076-1.
<span class="bold">PMID: </span><a href="/pubmed/6947185" target="_blank">6947185</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Delayed%20eruption%20of%20primary%20teeth%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (41)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/37005999">Influence of gestational age on eruption of primary teeth in Indian children - A prospective longitudinal study.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Mysore ID,
Nandlal B,
Narayanappa D</span><br />
<span class="medgenPMjournal">Indian J Dent Res</span>
2022 Oct-Dec;33(4):373-377.
doi: 10.4103/ijdr.ijdr_56_22.
<span class="bold">PMID: </span><a href="/pubmed/37005999" target="_blank">37005999</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33341334">Oral manifestations of celiac disease in French children.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Villemur Moreau L,
Dicky O,
Mas E,
Noirrit E,
Marty M,
Vaysse F,
Olives JP</span><br />
<span class="medgenPMjournal">Arch Pediatr</span>
2021 Feb;28(2):105-110.
Epub 2020 Dec 17
doi: 10.1016/j.arcped.2020.11.002.
<span class="bold">PMID: </span><a href="/pubmed/33341334" target="_blank">33341334</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25183438">Increased number of teeth predict acquisition of mutans streptococci in infants.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Nelson S,
Albert JM,
Soderling E,
Malik A,
Curtan S,
Geng C,
Milgrom P</span><br />
<span class="medgenPMjournal">Eur J Oral Sci</span>
2014 Oct;122(5):346-52.
Epub 2014 Sep 3
doi: 10.1111/eos.12147.
<span class="bold">PMID: </span><a href="/pubmed/25183438" target="_blank">25183438</a><a href="/pmc/articles/PMC4163102" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23729457">Management of ankylosed primary molars with premolar successors: a systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tieu LD,
Walker SL,
Major MP,
Flores-Mir C</span><br />
<span class="medgenPMjournal">J Am Dent Assoc</span>
2013 Jun;144(6):602-11.
doi: 10.14219/jada.archive.2013.0171.
<span class="bold">PMID: </span><a href="/pubmed/23729457" target="_blank">23729457</a></div>
<div class="nl"><a target="_blank" href="/pubmed/9635316">Delayed tooth eruption in congenital hypertrichosis lanuginosa.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Franklin DL,
Roberts GJ</span><br />
<span class="medgenPMjournal">Pediatr Dent</span>
1998 May-Jun;20(3):192-4.
<span class="bold">PMID: </span><a href="/pubmed/9635316" target="_blank">9635316</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Delayed%20eruption%20of%20primary%20teeth%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (54)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/37005999">Influence of gestational age on eruption of primary teeth in Indian children - A prospective longitudinal study.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Mysore ID,
Nandlal B,
Narayanappa D</span><br />
<span class="medgenPMjournal">Indian J Dent Res</span>
2022 Oct-Dec;33(4):373-377.
doi: 10.4103/ijdr.ijdr_56_22.
<span class="bold">PMID: </span><a href="/pubmed/37005999" target="_blank">37005999</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35833575">An overview of the intraoral features and craniofacial morphology of growing and adult Japanese cleidocranial dysplasia subjects.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Shih-Wei Cheng E,
Tsuji M,
Suzuki S,
Moriyama K</span><br />
<span class="medgenPMjournal">Eur J Orthod</span>
2022 Dec 1;44(6):711-722.
doi: 10.1093/ejo/cjac039.
<span class="bold">PMID: </span><a href="/pubmed/35833575" target="_blank">35833575</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29402820">Primary Fused Teeth and Findings in Permanent Dentition.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">ıkel H,
İbiş S,
Şen Tunç E</span><br />
<span class="medgenPMjournal">Med Princ Pract</span>
2018;27(2):129-132.
Epub 2018 Feb 1
doi: 10.1159/000487322.
<span class="bold">PMID: </span><a href="/pubmed/29402820" target="_blank">29402820</a><a href="/pmc/articles/PMC5968246" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25183438">Increased number of teeth predict acquisition of mutans streptococci in infants.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Nelson S,
Albert JM,
Soderling E,
Malik A,
Curtan S,
Geng C,
Milgrom P</span><br />
<span class="medgenPMjournal">Eur J Oral Sci</span>
2014 Oct;122(5):346-52.
Epub 2014 Sep 3
doi: 10.1111/eos.12147.
<span class="bold">PMID: </span><a href="/pubmed/25183438" target="_blank">25183438</a><a href="/pmc/articles/PMC4163102" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/14969379">Crouzonodermoskeletal syndrome.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Jeftha A,
Stephen L,
Morkel JA,
Beighton P</span><br />
<span class="medgenPMjournal">J Clin Pediatr Dent</span>
2004 Winter;28(2):173-6.
doi: 10.17796/jcpd.28.2.72m01l5g50448548.
<span class="bold">PMID: </span><a href="/pubmed/14969379" target="_blank">14969379</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Delayed%20eruption%20of%20primary%20teeth%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (72)</a></div></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="nl"><a target="_blank" href="/pubmed/38128337">Global variations in eruption chronology of primary teeth: A systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Muthu MS,
Vandana S,
Akila G,
Anusha M,
Kandaswamy D,
Aswath Narayanan MB</span><br />
<span class="medgenPMjournal">Arch Oral Biol</span>
2024 Feb;158:105857.
Epub 2023 Dec 6
doi: 10.1016/j.archoralbio.2023.105857.
<span class="bold">PMID: </span><a href="/pubmed/38128337" target="_blank">38128337</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36907703">Interventions to facilitate the successful eruption of impacted maxillary incisor teeth due to the presence of a supernumerary: A systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Seehra J,
Mortaja K,
Wazwaz F,
Papageorgiou SN,
Newton JT,
Cobourne MT</span><br />
<span class="medgenPMjournal">Am J Orthod Dentofacial Orthop</span>
2023 May;163(5):594-608.
Epub 2023 Mar 11
doi: 10.1016/j.ajodo.2023.01.004.
<span class="bold">PMID: </span><a href="/pubmed/36907703" target="_blank">36907703</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34970995">Orthodontic treatment for crowded teeth in children.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Turner S,
Harrison JE,
Sharif FN,
Owens D,
Millett DT</span><br />
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
2021 Dec 31;12(12):CD003453.
doi: 10.1002/14651858.CD003453.pub2.
<span class="bold">PMID: </span><a href="/pubmed/34970995" target="_blank">34970995</a><a href="/pmc/articles/PMC8786262" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31075568">Dental development in cleft lip and palate patients: A systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Van Dyck J,
Cadenas de Llano-Pérula M,
Willems G,
Verdonck A</span><br />
<span class="medgenPMjournal">Forensic Sci Int</span>
2019 Jul;300:63-74.
Epub 2019 Apr 17
doi: 10.1016/j.forsciint.2019.04.011.
<span class="bold">PMID: </span><a href="/pubmed/31075568" target="_blank">31075568</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23729457">Management of ankylosed primary molars with premolar successors: a systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tieu LD,
Walker SL,
Major MP,
Flores-Mir C</span><br />
<span class="medgenPMjournal">J Am Dent Assoc</span>
2013 Jun;144(6):602-11.
doi: 10.14219/jada.archive.2013.0171.
<span class="bold">PMID: </span><a href="/pubmed/23729457" target="_blank">23729457</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Delayed%20eruption%20of%20primary%20teeth%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (8)</a></div></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(delayed%20eruption%20of%20primary%20teeth)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Delayed%20eruption%20of%20primary%20teeth%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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