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<meta name="keywords" content="C1835122, anatomical abnormality, thoracic lordosis, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Thoracic lordosis refers to an abnormal curvature of the thoracic spine in which the thoracic spine displays lordosis (inward curve) instead of the normal kyphosis (outward curve)." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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UID=331906
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ConceptID=C1835122
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Thoracic lordosis</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>331906</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1835122</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Anatomical Abnormality</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>HPO:</td>
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0430043">HP:0430043</a></td></tr>
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<div class="portlet_content ln">Thoracic lordosis refers to an abnormal curvature of the thoracic spine in which the thoracic spine displays lordosis (inward curve) instead of the normal kyphosis (outward curve). [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Thoracic lordosis</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/1763488" ref="tree=MeSH" title="MedGen record for Abnormality of the musculoskeletal system">Abnormality of the musculoskeletal system</a></span><ul><li><span class="TLline"><a href="/medgen/867418" ref="tree=MeSH" title="MedGen record for Abnormality of the skeletal system">Abnormality of the skeletal system</a></span><ul><li><span class="TLline"><a href="/medgen/868760" ref="tree=MeSH" title="MedGen record for Abnormal skeletal morphology">Abnormal skeletal morphology</a></span><ul><li><span class="TLline"><a href="/medgen/892434" ref="tree=MeSH" title="MedGen record for Abnormal axial skeleton morphology">Abnormal axial skeleton morphology</a></span><ul><li><span class="TLline"><a href="/medgen/892426" ref="tree=MeSH" title="MedGen record for Abnormality of the vertebral column">Abnormality of the vertebral column</a></span><ul><li><span class="TLline"><a href="/medgen/869321" ref="tree=MeSH" title="MedGen record for Abnormal curvature of the vertebral column">Abnormal curvature of the vertebral column</a></span><ul><li><span class="matched_ds">Thoracic lordosis</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln clinfeat">
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<div class="divPopper rprt" id="rdis_44287"><div><strong>Marfan syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>44287</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0024796</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">FBN1-related Marfan syndrome (Marfan syndrome), a systemic disorder of connective tissue with a high degree of clinical variability, comprises a broad phenotypic continuum ranging from mild (features of Marfan syndrome in one or a few systems) to severe and rapidly progressive neonatal multiorgan disease. Cardinal manifestations involve the ocular, skeletal, and cardiovascular systems. Ocular findings include myopia (>50% of affected individuals); ectopia lentis (seen in approximately 60% of affected individuals); and an increased risk for retinal detachment, glaucoma, and early cataracts. Skeletal system manifestations include bone overgrowth and joint laxity; disproportionately long extremities for the size of the trunk (dolichostenomelia); overgrowth of the ribs that can push the sternum in (pectus excavatum) or out (pectus carinatum); and scoliosis that ranges from mild to severe and progressive. The major morbidity and early mortality in Marfan syndrome relate to the cardiovascular system and include dilatation of the aorta at the level of the sinuses of Valsalva (predisposing to aortic tear and rupture), mitral valve prolapse with or without regurgitation, tricuspid valve prolapse, and enlargement of the proximal pulmonary artery. Severe and prolonged regurgitation of the mitral and/or aortic valve can predispose to left ventricular dysfunction and occasionally heart failure. With proper management, the life expectancy of someone with Marfan syndrome approximates that of the general population.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/44287">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_75556"><div><strong>Coffin-Lowry syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>75556</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0265252</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The phenotypic spectrum associated with RPS6KA3 pathogenic variants is a continuum. Coffin-Lowry syndrome (CLS) classically manifests in males with developmental delay, intellectual disability, neurologic manifestations (hypotonia, stimulus-induced drop attacks, spastic paraparesis, and seizures), musculoskeletal manifestations (kyphoscoliosis and pectus deformity), and characteristic craniofacial and hand findings. Dental issues, sensorineural hearing loss, and obstructive sleep apnea also occur. The milder end of the continuum in males includes neurodevelopmental disabilities with or without less pronounced multisystem involvement. Heterozygous females often exhibit clinical manifestations that can be consistent with clinically defined CLS but are typically less severe than those seen in affected males. Developmental delay and intellectual disability comprise the core phenotypic findings, and quality of life and prognosis are variably affected by the presence and severity of neurologic and musculoskeletal involvement.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/75556">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_356497"><div><strong>Ehlers-Danlos syndrome, musculocontractural type</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>356497</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1866294</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Bleeding problems are common in the vascular type of Ehlers-Danlos syndrome and are caused by unpredictable tearing (rupture) of blood vessels and organs. These complications can lead to easy bruising, internal bleeding, a hole in the wall of the intestine (intestinal perforation), or stroke. During pregnancy, women with vascular Ehlers-Danlos syndrome may experience rupture of the uterus. Additional forms of Ehlers-Danlos syndrome that involve rupture of the blood vessels include the kyphoscoliotic, classical, and classical-like types.\n\nOther types of Ehlers-Danlos syndrome have additional signs and symptoms. The cardiac-valvular type causes severe problems with the valves that control the movement of blood through the heart. People with the kyphoscoliotic type experience severe curvature of the spine that worsens over time and can interfere with breathing by restricting lung expansion. A type of Ehlers-Danlos syndrome called brittle cornea syndrome is characterized by thinness of the clear covering of the eye (the cornea) and other eye abnormalities. The spondylodysplastic type features short stature and skeletal abnormalities such as abnormally curved (bowed) limbs. Abnormalities of muscles, including hypotonia and permanently bent joints (contractures), are among the characteristic signs of the musculocontractural and myopathic forms of Ehlers-Danlos syndrome. The periodontal type causes abnormalities of the teeth and gums.\n\nMany people with the Ehlers-Danlos syndromes have soft, velvety skin that is highly stretchy (elastic) and fragile. Affected individuals tend to bruise easily, and some types of the condition also cause abnormal scarring. People with the classical form of Ehlers-Danlos syndrome experience wounds that split open with little bleeding and leave scars that widen over time to create characteristic "cigarette paper" scars. The dermatosparaxis type of the disorder is characterized by loose skin that sags and wrinkles, and extra (redundant) folds of skin may be present.\n\nAn unusually large range of joint movement (hypermobility) occurs in most forms of Ehlers-Danlos syndrome, and it is a hallmark feature of the hypermobile type. Infants and children with hypermobility often have weak muscle tone (hypotonia), which can delay the development of motor skills such as sitting, standing, and walking. The loose joints are unstable and prone to dislocation and chronic pain. In the arthrochalasia type of Ehlers-Danlos syndrome, infants have hypermobility and dislocations of both hips at birth.\n\nThe various forms of Ehlers-Danlos syndrome have been classified in several different ways. Originally, 11 forms of Ehlers-Danlos syndrome were named using Roman numerals to indicate the types (type I, type II, and so on). In 1997, researchers proposed a simpler classification (the Villefranche nomenclature) that reduced the number of types to six and gave them descriptive names based on their major features. In 2017, the classification was updated to include rare forms of Ehlers-Danlos syndrome that were identified more recently. The 2017 classification describes 13 types of Ehlers-Danlos syndrome.\n\nEhlers-Danlos syndrome is a group of disorders that affect connective tissues supporting the skin, bones, blood vessels, and many other organs and tissues. Defects in connective tissues cause the signs and symptoms of these conditions, which range from mildly loose joints to life-threatening complications.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/356497">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_75556" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Coffin-Lowry syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_356497" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Ehlers-Danlos syndrome, musculocontractural type</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_44287" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Marfan syndrome</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/22706465">Comparative analysis of hook, hybrid, and pedicle screw instrumentation in the posterior treatment of adolescent idiopathic scoliosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yilmaz G,
|
||
Borkhuu B,
|
||
Dhawale AA,
|
||
Oto M,
|
||
Littleton AG,
|
||
Mason DE,
|
||
Gabos PG,
|
||
Shah SA</span><br />
|
||
<span class="medgenPMjournal">J Pediatr Orthop</span>
|
||
2012 Jul-Aug;32(5):490-9.
|
||
doi: 10.1097/BPO.0b013e318250c629.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22706465" target="_blank">22706465</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/4071269">Spinal deformities in patients with muscular dystrophy other than Duchenne. A review of 11 patients having surgical treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Daher YH,
|
||
Lonstein JE,
|
||
Winter RB,
|
||
Bradford DS</span><br />
|
||
<span class="medgenPMjournal">Spine (Phila Pa 1976)</span>
|
||
1985 Sep;10(7):614-7.
|
||
doi: 10.1097/00007632-198509000-00004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/4071269" target="_blank">4071269</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7202867">Treatment of extension contracture of the hip in cerebral palsy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bowen JR,
|
||
MacEwen GD,
|
||
Mathews PA</span><br />
|
||
<span class="medgenPMjournal">Dev Med Child Neurol</span>
|
||
1981 Feb;23(1):23-9.
|
||
doi: 10.1111/j.1469-8749.1981.tb08443.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7202867" target="_blank">7202867</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22thoracic%20lordosis%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (3)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37698696">Kyphectomy in myelomeningocele revisited: risk factors for failure.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ghanem I,
|
||
Saliba I,
|
||
Ghanem D,
|
||
Assi A,
|
||
Dubousset J,
|
||
Bernstein S,
|
||
Tolo V,
|
||
Bassett G,
|
||
Miladi L</span><br />
|
||
<span class="medgenPMjournal">Eur Spine J</span>
|
||
2023 Dec;32(12):4128-4144.
|
||
Epub 2023 Sep 12
|
||
doi: 10.1007/s00586-023-07924-w.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37698696" target="_blank">37698696</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33025194">The potential of spring distraction to dynamically correct complex spinal deformities in the growing child.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wijdicks SPJ,
|
||
Lemans JVC,
|
||
Verkerke GJ,
|
||
Noordmans HJ,
|
||
Castelein RM,
|
||
Kruyt MC</span><br />
|
||
<span class="medgenPMjournal">Eur Spine J</span>
|
||
2021 Mar;30(3):714-723.
|
||
Epub 2020 Oct 6
|
||
doi: 10.1007/s00586-020-06612-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33025194" target="_blank">33025194</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30260921">Thoracic Lordosis, Especially in Males, Increases Blood Loss in Adolescent Idiopathic Scoliosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Abousamra O,
|
||
Sponseller PD,
|
||
Lonner BS,
|
||
Shah SA,
|
||
Marks MC,
|
||
Cahill PJ,
|
||
Pahys JM,
|
||
Newton PO;
|
||
Harms Study Group</span><br />
|
||
<span class="medgenPMjournal">J Pediatr Orthop</span>
|
||
2019 Mar;39(3):e201-e204.
|
||
doi: 10.1097/BPO.0000000000001264.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30260921" target="_blank">30260921</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27171667">The Thoracic Lordosis Correction Improves Sacral Slope and Walking Ability in Neuromuscular Scoliosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kim do Y,
|
||
Moon ES,
|
||
Park JO,
|
||
Chong HS,
|
||
Lee HM,
|
||
Moon SH,
|
||
Kim SH,
|
||
Kim HS</span><br />
|
||
<span class="medgenPMjournal">Clin Spine Surg</span>
|
||
2016 Oct;29(8):E413-20.
|
||
doi: 10.1097/BSD.0b013e318294368e.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27171667" target="_blank">27171667</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2250071">Surgical correction of congenital thoracic lordosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Winter RB,
|
||
Leonard AS</span><br />
|
||
<span class="medgenPMjournal">J Pediatr Orthop</span>
|
||
1990 Nov-Dec;10(6):805-8.
|
||
doi: 10.1097/01241398-199011000-00020.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2250071" target="_blank">2250071</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Thoracic%20lordosis%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (27)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/28542051">Critical Airway Stenosis in an Adolescent Male With Pompe Disease and Thoracic Lordosis: A Case Report.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Brenn BR,
|
||
Theroux MT,
|
||
Shah SA,
|
||
Mackenzie WG,
|
||
Heinle R,
|
||
Scavina MT</span><br />
|
||
<span class="medgenPMjournal">A A Case Rep</span>
|
||
2017 Oct 1;9(7):199-203.
|
||
doi: 10.1213/XAA.0000000000000564.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28542051" target="_blank">28542051</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27171667">The Thoracic Lordosis Correction Improves Sacral Slope and Walking Ability in Neuromuscular Scoliosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kim do Y,
|
||
Moon ES,
|
||
Park JO,
|
||
Chong HS,
|
||
Lee HM,
|
||
Moon SH,
|
||
Kim SH,
|
||
Kim HS</span><br />
|
||
<span class="medgenPMjournal">Clin Spine Surg</span>
|
||
2016 Oct;29(8):E413-20.
|
||
doi: 10.1097/BSD.0b013e318294368e.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27171667" target="_blank">27171667</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23813656">Orthopedic manifestations and implications for individuals with Costello syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Detweiler S,
|
||
Thacker MM,
|
||
Hopkins E,
|
||
Conway L,
|
||
Gripp KW</span><br />
|
||
<span class="medgenPMjournal">Am J Med Genet A</span>
|
||
2013 Aug;161A(8):1940-9.
|
||
Epub 2013 Jun 27
|
||
doi: 10.1002/ajmg.a.36047.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23813656" target="_blank">23813656</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2250071">Surgical correction of congenital thoracic lordosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Winter RB,
|
||
Leonard AS</span><br />
|
||
<span class="medgenPMjournal">J Pediatr Orthop</span>
|
||
1990 Nov-Dec;10(6):805-8.
|
||
doi: 10.1097/01241398-199011000-00020.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2250071" target="_blank">2250071</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/4093225">Spinal arthrodesis for spinal deformity using posterior instrumentation and sublaminar wiring. A preliminary report of 100 consecutive cases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Winter RB,
|
||
Anderson MB</span><br />
|
||
<span class="medgenPMjournal">Int Orthop</span>
|
||
1985;9(4):239-45.
|
||
doi: 10.1007/BF00266510.
|
||
<span class="bold">PMID: </span><a href="/pubmed/4093225" target="_blank">4093225</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Thoracic%20lordosis%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (18)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/30485184">Case-matched comparative analysis of spinal deformity correction in arthrogryposis multiplex congenita versus adolescent idiopathic scoliosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Xu L,
|
||
Chen Z,
|
||
Qiu Y,
|
||
Chen X,
|
||
Li S,
|
||
Du C,
|
||
Zhou Q,
|
||
Sun X</span><br />
|
||
<span class="medgenPMjournal">J Neurosurg Pediatr</span>
|
||
2019 Jan 1;23(1):22-29.
|
||
Epub 2018 Oct 12
|
||
doi: 10.3171/2018.7.PEDS18347.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30485184" target="_blank">30485184</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12709851">Surgical management of the spinal deformity in Ehlers-Danlos syndrome type VI.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Akpinar S,
|
||
Gogus A,
|
||
Talu U,
|
||
Hamzaoglu A,
|
||
Dikici F</span><br />
|
||
<span class="medgenPMjournal">Eur Spine J</span>
|
||
2003 Apr;12(2):135-40.
|
||
Epub 2002 Dec 20
|
||
doi: 10.1007/s00586-002-0507-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12709851" target="_blank">12709851</a><a href="/pmc/articles/PMC3784844" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11891459">Progressive spinal lordosis after laminoplasty in a child with thoracic neuroblastoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hosalkar HS,
|
||
Pill SG,
|
||
Sun PP,
|
||
Drummond DS</span><br />
|
||
<span class="medgenPMjournal">J Spinal Disord Tech</span>
|
||
2002 Feb;15(1):79-83.
|
||
doi: 10.1097/00024720-200202000-00016.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11891459" target="_blank">11891459</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9604276">Biomechanical evaluation of the Milwaukee brace.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wong MS,
|
||
Evans JH</span><br />
|
||
<span class="medgenPMjournal">Prosthet Orthot Int</span>
|
||
1998 Apr;22(1):54-67.
|
||
doi: 10.3109/03093649809164457.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9604276" target="_blank">9604276</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2777844">Surgical treatment of adolescent idiopathic scoliosis. A comparative analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mielke CH,
|
||
Lonstein JE,
|
||
Denis F,
|
||
Vandenbrink K,
|
||
Winter RB</span><br />
|
||
<span class="medgenPMjournal">J Bone Joint Surg Am</span>
|
||
1989 Sep;71(8):1170-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2777844" target="_blank">2777844</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Thoracic%20lordosis%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (6)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33025194">The potential of spring distraction to dynamically correct complex spinal deformities in the growing child.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wijdicks SPJ,
|
||
Lemans JVC,
|
||
Verkerke GJ,
|
||
Noordmans HJ,
|
||
Castelein RM,
|
||
Kruyt MC</span><br />
|
||
<span class="medgenPMjournal">Eur Spine J</span>
|
||
2021 Mar;30(3):714-723.
|
||
Epub 2020 Oct 6
|
||
doi: 10.1007/s00586-020-06612-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33025194" target="_blank">33025194</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30260921">Thoracic Lordosis, Especially in Males, Increases Blood Loss in Adolescent Idiopathic Scoliosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Abousamra O,
|
||
Sponseller PD,
|
||
Lonner BS,
|
||
Shah SA,
|
||
Marks MC,
|
||
Cahill PJ,
|
||
Pahys JM,
|
||
Newton PO;
|
||
Harms Study Group</span><br />
|
||
<span class="medgenPMjournal">J Pediatr Orthop</span>
|
||
2019 Mar;39(3):e201-e204.
|
||
doi: 10.1097/BPO.0000000000001264.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30260921" target="_blank">30260921</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27171667">The Thoracic Lordosis Correction Improves Sacral Slope and Walking Ability in Neuromuscular Scoliosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kim do Y,
|
||
Moon ES,
|
||
Park JO,
|
||
Chong HS,
|
||
Lee HM,
|
||
Moon SH,
|
||
Kim SH,
|
||
Kim HS</span><br />
|
||
<span class="medgenPMjournal">Clin Spine Surg</span>
|
||
2016 Oct;29(8):E413-20.
|
||
doi: 10.1097/BSD.0b013e318294368e.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27171667" target="_blank">27171667</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23813656">Orthopedic manifestations and implications for individuals with Costello syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Detweiler S,
|
||
Thacker MM,
|
||
Hopkins E,
|
||
Conway L,
|
||
Gripp KW</span><br />
|
||
<span class="medgenPMjournal">Am J Med Genet A</span>
|
||
2013 Aug;161A(8):1940-9.
|
||
Epub 2013 Jun 27
|
||
doi: 10.1002/ajmg.a.36047.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23813656" target="_blank">23813656</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2250071">Surgical correction of congenital thoracic lordosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Winter RB,
|
||
Leonard AS</span><br />
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||
<span class="medgenPMjournal">J Pediatr Orthop</span>
|
||
1990 Nov-Dec;10(6):805-8.
|
||
doi: 10.1097/01241398-199011000-00020.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2250071" target="_blank">2250071</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Thoracic%20lordosis%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (15)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38430152">Rare Sagittal Compensatory Balance in Neuromuscular Scoliosis Complicated by Hydrocephalus: A Case Report.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang J,
|
||
Zhang Z,
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||
Yuan S</span><br />
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<span class="medgenPMjournal">Altern Ther Health Med</span>
|
||
2024 Nov;30(11):248-251.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38430152" target="_blank">38430152</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30260921">Thoracic Lordosis, Especially in Males, Increases Blood Loss in Adolescent Idiopathic Scoliosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Abousamra O,
|
||
Sponseller PD,
|
||
Lonner BS,
|
||
Shah SA,
|
||
Marks MC,
|
||
Cahill PJ,
|
||
Pahys JM,
|
||
Newton PO;
|
||
Harms Study Group</span><br />
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<span class="medgenPMjournal">J Pediatr Orthop</span>
|
||
2019 Mar;39(3):e201-e204.
|
||
doi: 10.1097/BPO.0000000000001264.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30260921" target="_blank">30260921</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28612190">Correction of hypokyphosis in thoracic adolescent idiopathic scoliosis using sublaminar bands: a 3D multicenter study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ilharreborde B,
|
||
Pesenti S,
|
||
Ferrero E,
|
||
Accadbled F,
|
||
Jouve JL,
|
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De Gauzy JS,
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Mazda K</span><br />
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<span class="medgenPMjournal">Eur Spine J</span>
|
||
2018 Feb;27(2):350-357.
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||
Epub 2017 Jun 13
|
||
doi: 10.1007/s00586-017-5166-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28612190" target="_blank">28612190</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28422833">Correction of sagittal imbalance in treatment for adult degenerative scoliosis with thoracic lordosis and lumbar kyphosis: A case report.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang T,
|
||
Wang H,
|
||
Ma L,
|
||
Zhang D,
|
||
Ding WY</span><br />
|
||
<span class="medgenPMjournal">Medicine (Baltimore)</span>
|
||
2017 Apr;96(16):e6416.
|
||
doi: 10.1097/MD.0000000000006416.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28422833" target="_blank">28422833</a><a href="/pmc/articles/PMC5406049" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
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<div class="nl"><a target="_blank" href="/pubmed/27514676">The effects of the three-dimensional deformity of adolescent idiopathic scoliosis on pulmonary function.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yaszay B,
|
||
Bastrom TP,
|
||
Bartley CE,
|
||
Parent S,
|
||
Newton PO</span><br />
|
||
<span class="medgenPMjournal">Eur Spine J</span>
|
||
2017 Jun;26(6):1658-1664.
|
||
Epub 2016 Aug 11
|
||
doi: 10.1007/s00586-016-4694-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27514676" target="_blank">27514676</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Thoracic%20lordosis%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (9)</a></div></div>
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