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<!--
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UID=322417
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ConceptID=C1834433
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Obsessive-compulsive trait</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>322417</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1834433</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
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<td>Obsessive-compulsive traits</td></tr>
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<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0008770">HP:0008770</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">The presence of one or more obsessive-compulsive personality traits. Obsessions refer to persistent intrusive thoughts, and compulsions to intrusive behaviors, which the affected person experiences as involuntary, senseless, or repugnant. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Obsessive-compulsive trait</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/1056192" ref="tree=MeSH" title="MedGen record for Abnormal affect">Abnormal affect</a></span><ul><li><span class="TLline"><a href="/medgen/1053648" ref="tree=MeSH" title="MedGen record for Abnormal volitional state">Abnormal volitional state</a></span><ul><li><span class="TLline"><a href="/medgen/1853215" ref="tree=MeSH" title="MedGen record for Abnormally increased volition">Abnormally increased volition</a></span><ul><li><span class="TLline"><a href="/medgen/5769" ref="tree=MeSH" title="MedGen record for Impulse control disorder">Impulse control disorder</a></span><ul><li><span class="TLline"><a href="/medgen/43850" ref="tree=MeSH" title="MedGen record for Impulsivity">Impulsivity</a></span><ul><li><span class="TLline"><a href="/medgen/109373" ref="tree=MeSH" title="MedGen record for Compulsive behaviors">Compulsive behaviors</a></span><ul><li><span class="matched_ds">Obsessive-compulsive trait</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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||
</div>
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||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_6708"><div><strong>Pigmentary pallidal degeneration</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>6708</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0018523</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Pantothenate kinase-associated neurodegeneration (PKAN) is a type of neurodegeneration with brain iron accumulation (NBIA). The phenotypic spectrum of PKAN includes classic PKAN and atypical PKAN. Classic PKAN is characterized by early-childhood onset of progressive dystonia, dysarthria, rigidity, and choreoathetosis. Pigmentary retinal degeneration is common. Atypical PKAN is characterized by later onset (age >10 years), prominent speech defects, psychiatric disturbances, and more gradual progression of disease.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/6708">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_59799"><div><strong>Williams syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>59799</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0175702</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Williams syndrome (WS) is characterized by developmental delay, intellectual disability (usually mild), a specific cognitive profile, unique personality characteristics, cardiovascular disease (supravalvar aortic stenosis, peripheral pulmonary stenosis, hypertension), connective tissue abnormalities, growth deficiency, endocrine abnormalities (early puberty, hypercalcemia, hypercalciuria, hypothyroidism), and distinctive facies. Hypotonia and hyperextensible joints can result in delayed attainment of motor milestones. Feeding difficulties often lead to poor weight gain in infancy.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/59799">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_333403"><div><strong>Fragile X-associated tremor/ataxia syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>333403</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1839780</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">FMR1 disorders include fragile X syndrome (FXS), fragile X-associated tremor/ataxia syndrome (FXTAS), and fragile X-associated primary ovarian insufficiency (FXPOI). Fragile X syndrome occurs in individuals with an FMR1 full mutation or other loss-of-function variant and is nearly always characterized in affected males by developmental delay and intellectual disability along with a variety of behavioral issues. Autism spectrum disorder is present in 50%-70% of individuals with FXS. Affected males may have characteristic craniofacial features (which become more obvious with age) and medical problems including hypotonia, gastroesophageal reflux, strabismus, seizures, sleep disorders, joint laxity, pes planus, scoliosis, and recurrent otitis media. Adults may have mitral valve prolapse or aortic root dilatation. The physical and behavioral features seen in males with FXS have been reported in females heterozygous for the FMR1 full mutation, but with lower frequency and milder involvement. FXTAS occurs in individuals who have an FMR1 premutation and is characterized by late-onset, progressive cerebellar ataxia and intention tremor followed by cognitive impairment. Psychiatric disorders are common. Age of onset is typically between 60 and 65 years and is more common among males who are hemizygous for the premutation (40%) than among females who are heterozygous for the premutation (16%-20%). FXPOI, defined as hypergonadotropic hypogonadism before age 40 years, has been observed in 20% of women who carry a premutation allele compared to 1% in the general population.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/333403">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_886881"><div><strong>Steinert myotonic dystrophy syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>886881</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3250443</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Myotonic dystrophy type 1 (DM1) is a multisystem disorder that affects skeletal and smooth muscle as well as the eye, heart, endocrine system, and central nervous system. The clinical findings, which span a continuum from mild to severe, have been categorized into three somewhat overlapping phenotypes: mild, classic, and congenital. Mild DM1 is characterized by cataract and mild myotonia (sustained muscle contraction); life span is normal. Classic DM1 is characterized by muscle weakness and wasting, myotonia, cataract, and often cardiac conduction abnormalities; adults may become physically disabled and may have a shortened life span. Congenital DM1 is characterized by hypotonia and severe generalized weakness at birth, often with respiratory insufficiency and early death; intellectual disability is common.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/886881">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1379216"><div><strong>Intellectual developmental disorder with neuropsychiatric features</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1379216</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4479636</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Intellectual developmental disorder with neuropsychiatric features is an autosomal recessive disorder characterized by moderate intellectual disability, relatively mild seizures, and neuropsychiatric abnormalities, such as anxiety, obsessive-compulsive behavior, and autistic features. Mild facial dysmorphic features may also be present (summary by Srour et al., 2017).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1379216">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1621755"><div><strong>Developmental and epileptic encephalopathy, 56</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1621755</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4540034</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Developmental and epileptic encephalopathy-56 (DEE56) is a neurodevelopmental disorder characterized by early-onset seizures in most patients, followed by impaired intellectual development, variable behavioral abnormalities, and sometimes additional neurologic features, such as ataxia (summary by Guella et al., 2017). For a general phenotypic description and a discussion of genetic heterogeneity of DEE, see 308350.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1621755">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1615839"><div><strong>Intellectual disability, autosomal dominant 52</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1615839</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4540478</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Mental or Behavioral Dysfunction</dd></dl></div></div></div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1615839">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1716581"><div><strong>Intellectual developmental disorder, autosomal dominant 63, with macrocephaly</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1716581</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5394205</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">TRIO-related neurodevelopmental disorder (TRIO-NDD) is characterized by two phenotypes: TRIO-NDD due to gain-of-function variants and TRIO-NDD due to loss-of-function variants. TRIO-NDD due to gain-of-function variants within the spectrin repeat domain is characterized by moderate-to-severe developmental delay, intellectual disability, macrocephaly (or relative macrocephaly), neurobehavioral manifestations (poor attention, stereotypies, obsessive-compulsive behavior, aggressive behavior, and autism spectrum disorder), and early feeding difficulties with poor weight gain and growth deficiency. Seizures, constipation, scoliosis, dental abnormalities, and cardiac anomalies are also reported. TRIO-NDD due to loss-of-function variants is characterized by mild-to-moderate developmental delay and intellectual disability, microcephaly, neurobehavioral manifestations (poor attention, aggressive behavior, autism spectrum disorder, obsessive-compulsive traits, and stereotypies), early feeding difficulties with poor weight gain, dental abnormalities, and digit anomalies, including 2-3 toe syndactyly in some individuals. Seizures, constipation, scoliosis, and cardiac anomalies are also reported.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1716581">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1805816"><div><strong>Neurodevelopmental disorder with language delay and seizures</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1805816</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5676998</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Neurodevelopmental disorder with language delay and seizures (NEDLDS) is an autosomal recessive disorder characterized by global developmental delay with mild to severely impaired intellectual development and speech delay with poor or absent language. Affected individuals develop early-onset seizures that are usually well-controlled with medication. Additional features may include axial hypotonia, peripheral hypertonia, hypothyroidism, and nonspecific dysmorphic features or brain imaging abnormalities (Lu et al., 2022).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1805816">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1844192"><div><strong>Intellectual developmental disorder, autosomal recessive 81</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1844192</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5882758</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Autosomal recessive intellectual developmental disorder-81 (MRT81) is characterized by a variable neurobehavioral and neuromuscular phenotype (summary by Nair et al., 2021).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1844192">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1621755" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Developmental and epileptic encephalopathy, 56</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_333403" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Fragile X-associated tremor/ataxia syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1379216" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Intellectual developmental disorder with neuropsychiatric features</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1716581" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Intellectual developmental disorder, autosomal dominant 63, with macrocephaly</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1844192" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Intellectual developmental disorder, autosomal recessive 81</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (10)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1615839" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Intellectual disability, autosomal dominant 52</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1805816" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Neurodevelopmental disorder with language delay and seizures</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_6708" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Pigmentary pallidal degeneration</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_886881" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Steinert myotonic dystrophy syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_59799" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Williams syndrome</a></div></span></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38452608">Consensus guidelines for the diagnosis and management of succinic semialdehyde dehydrogenase deficiency.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tokatly Latzer I,
|
||
Bertoldi M,
|
||
Blau N,
|
||
DiBacco ML,
|
||
Elsea SH,
|
||
García-Cazorla À,
|
||
Gibson KM,
|
||
Gropman AL,
|
||
Hanson E,
|
||
Hoffman C,
|
||
Jeltsch K,
|
||
Juliá-Palacios N,
|
||
Knerr I,
|
||
Lee HHC,
|
||
Malaspina P,
|
||
McConnell A,
|
||
Opladen T,
|
||
Oppebøen M,
|
||
Rotenberg A,
|
||
Walterfang M,
|
||
Wang-Tso L,
|
||
Wevers RA,
|
||
Roullet JB,
|
||
Pearl PL</span><br />
|
||
<span class="medgenPMjournal">Mol Genet Metab</span>
|
||
2024 May;142(1):108363.
|
||
Epub 2024 Mar 4
|
||
doi: 10.1016/j.ymgme.2024.108363.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38452608" target="_blank">38452608</a><a href="/pmc/articles/PMC11073920" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31152643">Different Clinical Expression of Anxiety Disorders in Children and Adolescents: Assessment and Treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pop-Jordanova N</span><br />
|
||
<span class="medgenPMjournal">Pril (Makedon Akad Nauk Umet Odd Med Nauki)</span>
|
||
2019 May 1;40(1):5-40.
|
||
doi: 10.2478/prilozi-2019-0001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31152643" target="_blank">31152643</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27419272">Biological markers for anxiety disorders, OCD and PTSD: A consensus statement. Part II: Neurochemistry, neurophysiology and neurocognition.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bandelow B,
|
||
Baldwin D,
|
||
Abelli M,
|
||
Bolea-Alamanac B,
|
||
Bourin M,
|
||
Chamberlain SR,
|
||
Cinosi E,
|
||
Davies S,
|
||
Domschke K,
|
||
Fineberg N,
|
||
Grünblatt E,
|
||
Jarema M,
|
||
Kim YK,
|
||
Maron E,
|
||
Masdrakis V,
|
||
Mikova O,
|
||
Nutt D,
|
||
Pallanti S,
|
||
Pini S,
|
||
Ströhle A,
|
||
Thibaut F,
|
||
Vaghi MM,
|
||
Won E,
|
||
Wedekind D,
|
||
Wichniak A,
|
||
Woolley J,
|
||
Zwanzger P,
|
||
Riederer P</span><br />
|
||
<span class="medgenPMjournal">World J Biol Psychiatry</span>
|
||
2017 Apr;18(3):162-214.
|
||
Epub 2016 Jul 15
|
||
doi: 10.1080/15622975.2016.1190867.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27419272" target="_blank">27419272</a><a href="/pmc/articles/PMC5341771" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(obsessive-compulsive%20trait)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (51)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39402683">Harm avoidance and incompleteness core motivations in obsessive-compulsive disorder: validation of the Farsi version of the Obsessive-Compulsive Trait Core Dimensions Questionnaire (F-OC-TCDQ) in Iran.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pourebrahimi M,
|
||
Sarafraz M,
|
||
Hadianfard H,
|
||
Mohammadi N</span><br />
|
||
<span class="medgenPMjournal">BMC Psychol</span>
|
||
2024 Oct 15;12(1):552.
|
||
doi: 10.1186/s40359-024-02058-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39402683" target="_blank">39402683</a><a href="/pmc/articles/PMC11475546" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31321769">Serotonin system genes and obsessive-compulsive trait dimensions in a population-based, pediatric sample: a genetic association study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sinopoli VM,
|
||
Erdman L,
|
||
Burton CL,
|
||
Park LS,
|
||
Dupuis A,
|
||
Shan J,
|
||
Goodale T,
|
||
Shaheen SM,
|
||
Crosbie J,
|
||
Schachar RJ,
|
||
Arnold PD</span><br />
|
||
<span class="medgenPMjournal">J Child Psychol Psychiatry</span>
|
||
2019 Dec;60(12):1289-1299.
|
||
Epub 2019 Jul 19
|
||
doi: 10.1111/jcpp.13079.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31321769" target="_blank">31321769</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23774010">Avoidance and behavioural flexibility in obsessive compulsive disorder.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hassoulas A,
|
||
McHugh L,
|
||
Reed P</span><br />
|
||
<span class="medgenPMjournal">J Anxiety Disord</span>
|
||
2014 Mar;28(2):148-53.
|
||
Epub 2013 May 27
|
||
doi: 10.1016/j.janxdis.2013.05.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23774010" target="_blank">23774010</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22644206">Obsessive-compulsive aspects as predictors of poor response to treatments in patients with chronic migraine and medication overuse.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Curone M,
|
||
D'Amico D,
|
||
Bussone G</span><br />
|
||
<span class="medgenPMjournal">Neurol Sci</span>
|
||
2012 May;33 Suppl 1:S211-3.
|
||
doi: 10.1007/s10072-012-1070-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22644206" target="_blank">22644206</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21533740">Psychopathological profile of patients with chronic migraine and medication overuse: study and findings in 50 cases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Curone M,
|
||
Tullo V,
|
||
Mea E,
|
||
Proietti-Cecchini A,
|
||
Peccarisi C,
|
||
Bussone G</span><br />
|
||
<span class="medgenPMjournal">Neurol Sci</span>
|
||
2011 May;32 Suppl 1:S177-9.
|
||
doi: 10.1007/s10072-011-0527-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21533740" target="_blank">21533740</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Obsessive-compulsive%20trait%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (6)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39402683">Harm avoidance and incompleteness core motivations in obsessive-compulsive disorder: validation of the Farsi version of the Obsessive-Compulsive Trait Core Dimensions Questionnaire (F-OC-TCDQ) in Iran.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pourebrahimi M,
|
||
Sarafraz M,
|
||
Hadianfard H,
|
||
Mohammadi N</span><br />
|
||
<span class="medgenPMjournal">BMC Psychol</span>
|
||
2024 Oct 15;12(1):552.
|
||
doi: 10.1186/s40359-024-02058-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39402683" target="_blank">39402683</a><a href="/pmc/articles/PMC11475546" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24867863">Prevalence and profile of obsessive-compulsive trait in patients with chronic migraine and medication overuse.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Curone M,
|
||
Tullo V,
|
||
Lovati C,
|
||
Proietti-Cecchini A,
|
||
D'Amico D</span><br />
|
||
<span class="medgenPMjournal">Neurol Sci</span>
|
||
2014 May;35 Suppl 1:185-7.
|
||
doi: 10.1007/s10072-014-1767-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24867863" target="_blank">24867863</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23774010">Avoidance and behavioural flexibility in obsessive compulsive disorder.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hassoulas A,
|
||
McHugh L,
|
||
Reed P</span><br />
|
||
<span class="medgenPMjournal">J Anxiety Disord</span>
|
||
2014 Mar;28(2):148-53.
|
||
Epub 2013 May 27
|
||
doi: 10.1016/j.janxdis.2013.05.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23774010" target="_blank">23774010</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23743134">Can protective factors moderate the detrimental effects of child maltreatment on personality functioning?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hengartner MP,
|
||
Müller M,
|
||
Rodgers S,
|
||
Rössler W,
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||
Ajdacic-Gross V</span><br />
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<span class="medgenPMjournal">J Psychiatr Res</span>
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||
2013 Sep;47(9):1180-6.
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Epub 2013 Jun 4
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doi: 10.1016/j.jpsychires.2013.05.005.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23743134" target="_blank">23743134</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22644206">Obsessive-compulsive aspects as predictors of poor response to treatments in patients with chronic migraine and medication overuse.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Curone M,
|
||
D'Amico D,
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||
Bussone G</span><br />
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||
<span class="medgenPMjournal">Neurol Sci</span>
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||
2012 May;33 Suppl 1:S211-3.
|
||
doi: 10.1007/s10072-012-1070-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22644206" target="_blank">22644206</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Obsessive-compulsive%20trait%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/23774010">Avoidance and behavioural flexibility in obsessive compulsive disorder.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hassoulas A,
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McHugh L,
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Reed P</span><br />
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<span class="medgenPMjournal">J Anxiety Disord</span>
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||
2014 Mar;28(2):148-53.
|
||
Epub 2013 May 27
|
||
doi: 10.1016/j.janxdis.2013.05.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23774010" target="_blank">23774010</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11448084">Psychopathology and personality characteristics in relation to blood serotonin in Tourette's syndrome and obsessive-compulsive disorder.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cath DC,
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Spinhoven P,
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||
Landman AD,
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van Kempen GM</span><br />
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<span class="medgenPMjournal">J Psychopharmacol</span>
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2001 Jun;15(2):111-9.
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doi: 10.1177/026988110101500208.
|
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<span class="bold">PMID: </span><a href="/pubmed/11448084" target="_blank">11448084</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Obsessive-compulsive%20trait%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39402683">Harm avoidance and incompleteness core motivations in obsessive-compulsive disorder: validation of the Farsi version of the Obsessive-Compulsive Trait Core Dimensions Questionnaire (F-OC-TCDQ) in Iran.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pourebrahimi M,
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||
Sarafraz M,
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||
Hadianfard H,
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Mohammadi N</span><br />
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<span class="medgenPMjournal">BMC Psychol</span>
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||
2024 Oct 15;12(1):552.
|
||
doi: 10.1186/s40359-024-02058-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39402683" target="_blank">39402683</a><a href="/pmc/articles/PMC11475546" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24867863">Prevalence and profile of obsessive-compulsive trait in patients with chronic migraine and medication overuse.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Curone M,
|
||
Tullo V,
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||
Lovati C,
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||
Proietti-Cecchini A,
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D'Amico D</span><br />
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<span class="medgenPMjournal">Neurol Sci</span>
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||
2014 May;35 Suppl 1:185-7.
|
||
doi: 10.1007/s10072-014-1767-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24867863" target="_blank">24867863</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22644206">Obsessive-compulsive aspects as predictors of poor response to treatments in patients with chronic migraine and medication overuse.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Curone M,
|
||
D'Amico D,
|
||
Bussone G</span><br />
|
||
<span class="medgenPMjournal">Neurol Sci</span>
|
||
2012 May;33 Suppl 1:S211-3.
|
||
doi: 10.1007/s10072-012-1070-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22644206" target="_blank">22644206</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21533740">Psychopathological profile of patients with chronic migraine and medication overuse: study and findings in 50 cases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Curone M,
|
||
Tullo V,
|
||
Mea E,
|
||
Proietti-Cecchini A,
|
||
Peccarisi C,
|
||
Bussone G</span><br />
|
||
<span class="medgenPMjournal">Neurol Sci</span>
|
||
2011 May;32 Suppl 1:S177-9.
|
||
doi: 10.1007/s10072-011-0527-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21533740" target="_blank">21533740</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Obsessive-compulsive%20trait%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39402683">Harm avoidance and incompleteness core motivations in obsessive-compulsive disorder: validation of the Farsi version of the Obsessive-Compulsive Trait Core Dimensions Questionnaire (F-OC-TCDQ) in Iran.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pourebrahimi M,
|
||
Sarafraz M,
|
||
Hadianfard H,
|
||
Mohammadi N</span><br />
|
||
<span class="medgenPMjournal">BMC Psychol</span>
|
||
2024 Oct 15;12(1):552.
|
||
doi: 10.1186/s40359-024-02058-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39402683" target="_blank">39402683</a><a href="/pmc/articles/PMC11475546" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33460785">Action inhibition in individuals with high obsessive-compulsive trait of incompleteness: An ERP study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dominke C,
|
||
Graham-Schmidt K,
|
||
Gentsch A,
|
||
Schütz-Bosbach S</span><br />
|
||
<span class="medgenPMjournal">Biol Psychol</span>
|
||
2021 Feb;159:108019.
|
||
Epub 2021 Jan 15
|
||
doi: 10.1016/j.biopsycho.2021.108019.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33460785" target="_blank">33460785</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31321769">Serotonin system genes and obsessive-compulsive trait dimensions in a population-based, pediatric sample: a genetic association study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sinopoli VM,
|
||
Erdman L,
|
||
Burton CL,
|
||
Park LS,
|
||
Dupuis A,
|
||
Shan J,
|
||
Goodale T,
|
||
Shaheen SM,
|
||
Crosbie J,
|
||
Schachar RJ,
|
||
Arnold PD</span><br />
|
||
<span class="medgenPMjournal">J Child Psychol Psychiatry</span>
|
||
2019 Dec;60(12):1289-1299.
|
||
Epub 2019 Jul 19
|
||
doi: 10.1111/jcpp.13079.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31321769" target="_blank">31321769</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30228290">Heritability of obsessive-compulsive trait dimensions in youth from the general population.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Burton CL,
|
||
Park LS,
|
||
Corfield EC,
|
||
Forget-Dubois N,
|
||
Dupuis A,
|
||
Sinopoli VM,
|
||
Shan J,
|
||
Goodale T,
|
||
Shaheen SM,
|
||
Crosbie J,
|
||
Schachar RJ,
|
||
Arnold PD</span><br />
|
||
<span class="medgenPMjournal">Transl Psychiatry</span>
|
||
2018 Sep 18;8(1):191.
|
||
doi: 10.1038/s41398-018-0249-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30228290" target="_blank">30228290</a><a href="/pmc/articles/PMC6143601" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22644206">Obsessive-compulsive aspects as predictors of poor response to treatments in patients with chronic migraine and medication overuse.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Curone M,
|
||
D'Amico D,
|
||
Bussone G</span><br />
|
||
<span class="medgenPMjournal">Neurol Sci</span>
|
||
2012 May;33 Suppl 1:S211-3.
|
||
doi: 10.1007/s10072-012-1070-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22644206" target="_blank">22644206</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Obsessive-compulsive%20trait%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (7)</a></div></div>
|
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|
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|
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|
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(obsessive-compulsive%20trait)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Obsessive-compulsive%20trait%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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<li>
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<a class="text-white" href="https://www.nih.gov/">NIH</a>
|
||
</li>
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||
<li>
|
||
<a class="text-white" href="https://www.hhs.gov/">HHS</a>
|
||
</li>
|
||
<li>
|
||
<a class="text-white" href="https://www.usa.gov/">USA.gov</a>
|
||
</li>
|
||
</ul>
|
||
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|
||
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|
||
</div>
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||
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