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<!--
UID=2874
ConceptID=C0007137
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Squamous cell carcinoma</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>2874</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0007137</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
<td>Epidermoid carcinoma</td></tr>
<tr><td><span class="bold">SNOMED CT: </span></td>
<td>Squamous cell carcinoma (402815007); Squamous carcinoma (1162767002); SCC - squamous cell carcinoma (1162767002); Squamous cell carcinoma (1162767002); Epidermoid carcinoma (1162767002); Squamous cell epithelioma (1162767002)</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0002860">HP:0002860</a></td></tr>
<tr><td>Monarch Initiative:</td>
<td><a href="https://monarchinitiative.org/disease/MONDO:0005096" target="_blank">MONDO:0005096</a></td></tr>
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">The presence of squamous cell carcinoma of the skin. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
</div>
<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0007137[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=2874">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=2874" ref="ncbi_uid=2874">V</a></span></span><span class="TLline">Squamous cell carcinoma</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/21047" ref="tree=MeSH" title="MedGen record for Pathological Conditions, Signs and Symptoms">Pathological Conditions, Signs and Symptoms</a></span><ul><li><span class="TLline"><a href="/medgen/18325" ref="tree=MeSH" title="MedGen record for Pathological process">Pathological process</a></span><ul><li><span class="TLline"><a href="/medgen/4347" ref="tree=MeSH" title="MedGen record for Disease">Disease</a></span><ul><li><span class="TLline"><a href="/medgen/10294" ref="tree=MeSH" title="MedGen record for Neoplasm">Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/277963" ref="tree=MeSH" title="MedGen record for Epithelial neoplasm">Epithelial neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/2867" ref="tree=MeSH" title="MedGen record for Carcinoma">Carcinoma</a></span><ul><li><span class="matched_ds">Squamous cell carcinoma</span><ul><li><span class="TLline"><a href="/medgen/272304" ref="tree=MeSH" title="MedGen record for Ampulla of vater squamous cell carcinoma">Ampulla of vater squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/237257" ref="tree=MeSH" title="MedGen record for Anal squamous cell carcinoma">Anal squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/233979" ref="tree=MeSH" title="MedGen record for Anal canal squamous cell carcinoma">Anal canal squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1779300" ref="tree=MeSH" title="MedGen record for Metastatic Anal Canal Squamous Cell Carcinoma">Metastatic Anal Canal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1786287" ref="tree=MeSH" title="MedGen record for Recurrent Anal Canal Squamous Cell Carcinoma">Recurrent Anal Canal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1729500" ref="tree=MeSH" title="MedGen record for Refractory Anal Canal Squamous Cell Carcinoma">Refractory Anal Canal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1784186" ref="tree=MeSH" title="MedGen record for Unresectable Anal Canal Squamous Cell Carcinoma">Unresectable Anal Canal Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/509511" ref="tree=MeSH" title="MedGen record for Anal Intraepithelial Neoplasia 3">Anal Intraepithelial Neoplasia 3</a></span></li><li><span class="TLline"><a href="/medgen/278071" ref="tree=MeSH" title="MedGen record for Anal margin squamous cell carcinoma">Anal margin squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/231066" ref="tree=MeSH" title="MedGen record for Anal verrucous carcinoma">Anal verrucous carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/79125" ref="tree=MeSH" title="MedGen record for Anus basaloid carcinoma">Anus basaloid carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/232295" ref="tree=MeSH" title="MedGen record for Human Papillomavirus-Related Anal Squamous Cell Carcinoma">Human Papillomavirus-Related Anal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1768146" ref="tree=MeSH" title="MedGen record for Metastatic Anal Squamous Cell Carcinoma">Metastatic Anal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1766830" ref="tree=MeSH" title="MedGen record for Recurrent Anal Squamous Cell Carcinoma">Recurrent Anal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1758331" ref="tree=MeSH" title="MedGen record for Unresectable Anal Squamous Cell Carcinoma">Unresectable Anal Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/266085" ref="tree=MeSH" title="MedGen record for Basaloid squamous cell carcinoma">Basaloid squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/231418" ref="tree=MeSH" title="MedGen record for Basaloid carcinoma of the penis">Basaloid carcinoma of the penis</a></span><ul><li><span class="TLline"><a href="/medgen/1701314" ref="tree=MeSH" title="MedGen record for Penile Papillary-Basaloid Carcinoma">Penile Papillary-Basaloid Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/267027" ref="tree=MeSH" title="MedGen record for Cervical basaloid carcinoma">Cervical basaloid carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/232156" ref="tree=MeSH" title="MedGen record for Esophageal basaloid carcinoma">Esophageal basaloid carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/234337" ref="tree=MeSH" title="MedGen record for Head and Neck Basaloid Squamous Cell Carcinoma">Head and Neck Basaloid Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1382431" ref="tree=MeSH" title="MedGen record for Floor of Mouth Basaloid Squamous Cell Carcinoma">Floor of Mouth Basaloid Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/353839" ref="tree=MeSH" title="MedGen record for Laryngeal Basaloid Squamous Cell Carcinoma">Laryngeal Basaloid Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/328304" ref="tree=MeSH" title="MedGen record for Nasopharyngeal Basaloid Squamous Cell Carcinoma">Nasopharyngeal Basaloid Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/926083" ref="tree=MeSH" title="MedGen record for Oropharyngeal Basaloid Squamous Cell Carcinoma">Oropharyngeal Basaloid Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/318198" ref="tree=MeSH" title="MedGen record for Lung Basaloid Squamous Cell Carcinoma">Lung Basaloid Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/233446" ref="tree=MeSH" title="MedGen record for Skin basaloid carcinoma">Skin basaloid carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/231420" ref="tree=MeSH" title="MedGen record for Thymic basaloid carcinoma">Thymic basaloid carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/275572" ref="tree=MeSH" title="MedGen record for Vaginal Basaloid Squamous Cell Carcinoma">Vaginal Basaloid Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/384496" ref="tree=MeSH" title="MedGen record for Vulvar basaloid squamous cell carcinoma">Vulvar basaloid squamous cell carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/124645" ref="tree=MeSH" title="MedGen record for Bladder squamous cell carcinoma">Bladder squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/307289" ref="tree=MeSH" title="MedGen record for Bladder urachal squamous cell carcinoma">Bladder urachal squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/267376" ref="tree=MeSH" title="MedGen record for Bladder verrucous carcinoma">Bladder verrucous carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/311262" ref="tree=MeSH" title="MedGen record for Schistosoma Hematobium-Related Bladder Verrucous Carcinoma">Schistosoma Hematobium-Related Bladder Verrucous Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1676311" ref="tree=MeSH" title="MedGen record for Metastatic Bladder Squamous Cell Carcinoma">Metastatic Bladder Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/208968" ref="tree=MeSH" title="MedGen record for Recurrent Bladder Squamous Cell Carcinoma">Recurrent Bladder Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/234773" ref="tree=MeSH" title="MedGen record for Schistosoma Hematobium-Related Bladder Squamous Cell Carcinoma">Schistosoma Hematobium-Related Bladder Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/163613" ref="tree=MeSH" title="MedGen record for Stage 0 Bladder Squamous Cell Carcinoma AJCC v6 and v7">Stage 0 Bladder Squamous Cell Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/208969" ref="tree=MeSH" title="MedGen record for Stage I Squamous Cell Carcinoma of the Bladder AJCC v6 and v7">Stage I Squamous Cell Carcinoma of the Bladder AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/163614" ref="tree=MeSH" title="MedGen record for Stage II Bladder Squamous Cell Carcinoma AJCC v6 and v7">Stage II Bladder Squamous Cell Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/163615" ref="tree=MeSH" title="MedGen record for Stage III Bladder Squamous Cell Carcinoma AJCC v6 and v7">Stage III Bladder Squamous Cell Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/208970" ref="tree=MeSH" title="MedGen record for Stage IV Bladder Squamous Cell Carcinoma AJCC v7">Stage IV Bladder Squamous Cell Carcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/14207" ref="tree=MeSH" title="MedGen record for Bowen disease of the skin">Bowen disease of the skin</a></span></li><li><span class="TLline"><a href="/medgen/124644" ref="tree=MeSH" title="MedGen record for Cervical squamous cell carcinoma">Cervical squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/309255" ref="tree=MeSH" title="MedGen record for Cervical keratinizing squamous cell carcinoma">Cervical keratinizing squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/308946" ref="tree=MeSH" title="MedGen record for Cervical lymphoepithelioma-like carcinoma">Cervical lymphoepithelioma-like carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/309426" ref="tree=MeSH" title="MedGen record for Cervical non-keratinizing squamous cell carcinoma">Cervical non-keratinizing squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/272100" ref="tree=MeSH" title="MedGen record for Cervical Squamous Cell Carcinoma In Situ">Cervical Squamous Cell Carcinoma In Situ</a></span></li><li><span class="TLline"><a href="/medgen/1793102" ref="tree=MeSH" title="MedGen record for Cervical Squamous Cell Carcinoma, Not Otherwise Specified">Cervical Squamous Cell Carcinoma, Not Otherwise Specified</a></span><ul><li><span class="TLline"><a href="/medgen/1793238" ref="tree=MeSH" title="MedGen record for Refractory Cervical Squamous Cell Carcinoma, Not Otherwise Specified">Refractory Cervical Squamous Cell Carcinoma, Not Otherwise Specified</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/275713" ref="tree=MeSH" title="MedGen record for Cervical verrucous carcinoma">Cervical verrucous carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1793103" ref="tree=MeSH" title="MedGen record for Human Papillomavirus-Independent Cervical Squamous Cell Carcinoma">Human Papillomavirus-Independent Cervical Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/232616" ref="tree=MeSH" title="MedGen record for Human Papillomavirus-Related Cervical Squamous Cell Carcinoma">Human Papillomavirus-Related Cervical Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/273911" ref="tree=MeSH" title="MedGen record for Cervical Papillary Squamous Cell Carcinoma">Cervical Papillary Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1665005" ref="tree=MeSH" title="MedGen record for Metastatic Cervical Squamous Cell Carcinoma">Metastatic Cervical Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1791020" ref="tree=MeSH" title="MedGen record for Advanced Cervical Squamous Cell Carcinoma">Advanced Cervical Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1775970" ref="tree=MeSH" title="MedGen record for Locally Advanced Cervical Squamous Cell Carcinoma">Locally Advanced Cervical Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/272565" ref="tree=MeSH" title="MedGen record for Microinvasive cervical squamous cell carcinoma">Microinvasive cervical squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1618606" ref="tree=MeSH" title="MedGen record for Recurrent Cervical Squamous Cell Carcinoma">Recurrent Cervical Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1793237" ref="tree=MeSH" title="MedGen record for Refractory Cervical Squamous Cell Carcinoma">Refractory Cervical Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1791019" ref="tree=MeSH" title="MedGen record for Unresectable Cervical Squamous Cell Carcinoma">Unresectable Cervical Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/317527" ref="tree=MeSH" title="MedGen record for Colorectal squamous cell carcinoma">Colorectal squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/272494" ref="tree=MeSH" title="MedGen record for Squamous cell carcinoma of colon">Squamous cell carcinoma of colon</a></span></li><li><span class="TLline"><a href="/medgen/235534" ref="tree=MeSH" title="MedGen record for Squamous cell carcinoma of rectum">Squamous cell carcinoma of rectum</a></span><ul><li><span class="TLline"><a href="/medgen/1736273" ref="tree=MeSH" title="MedGen record for Metastatic Rectal Squamous Cell Carcinoma">Metastatic Rectal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/234156" ref="tree=MeSH" title="MedGen record for Rectal cloacogenic carcinoma">Rectal cloacogenic carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1788072" ref="tree=MeSH" title="MedGen record for Refractory Rectal Squamous Cell Carcinoma">Refractory Rectal Squamous Cell Carcinoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/87558" ref="tree=MeSH" title="MedGen record for Conjunctival squamous cell carcinoma">Conjunctival squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1389134" ref="tree=MeSH" title="MedGen record for Conjunctival Keratoacanthoma">Conjunctival Keratoacanthoma</a></span></li><li><span class="TLline"><a href="/medgen/1746718" ref="tree=MeSH" title="MedGen record for Conjunctival Spindle Cell Carcinoma">Conjunctival Spindle Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/91102" ref="tree=MeSH" title="MedGen record for Cornea squamous cell carcinoma">Cornea squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/234217" ref="tree=MeSH" title="MedGen record for Endometrial squamous cell carcinoma">Endometrial squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1713110" ref="tree=MeSH" title="MedGen record for Recurrent Endometrial Squamous Cell Carcinoma">Recurrent Endometrial Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1718971" ref="tree=MeSH" title="MedGen record for Refractory Endometrial Squamous Cell Carcinoma">Refractory Endometrial Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/124635" ref="tree=MeSH" title="MedGen record for Esophageal squamous cell carcinoma">Esophageal squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/231048" ref="tree=MeSH" title="MedGen record for Alcohol-Related Esophageal Squamous Cell Carcinoma">Alcohol-Related Esophageal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1651886" ref="tree=MeSH" title="MedGen record for Cervical Esophagus Squamous Cell Carcinoma">Cervical Esophagus Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1668587" ref="tree=MeSH" title="MedGen record for Distal Esophagus Squamous Cell Carcinoma">Distal Esophagus Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/459481" ref="tree=MeSH" title="MedGen record for Esophageal Moderately Differentiated Squamous Cell Carcinoma">Esophageal Moderately Differentiated Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/459482" ref="tree=MeSH" title="MedGen record for Esophageal Poorly Differentiated Squamous Cell Carcinoma">Esophageal Poorly Differentiated Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/459478" ref="tree=MeSH" title="MedGen record for Esophageal Spindle Cell Carcinoma">Esophageal Spindle Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1616131" ref="tree=MeSH" title="MedGen record for Esophageal Squamous Cell Carcinoma by AJCC v7 Stage">Esophageal Squamous Cell Carcinoma by AJCC v7 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/1665436" ref="tree=MeSH" title="MedGen record for Stage 0 Esophageal Squamous Cell Carcinoma AJCC v7">Stage 0 Esophageal Squamous Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/1670269" ref="tree=MeSH" title="MedGen record for Stage I Esophageal Squamous Cell Carcinoma AJCC v7">Stage I Esophageal Squamous Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/1663911" ref="tree=MeSH" title="MedGen record for Stage II Esophageal Squamous Cell Carcinoma AJCC v7">Stage II Esophageal Squamous Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/1656563" ref="tree=MeSH" title="MedGen record for Stage III Esophageal Squamous Cell Carcinoma AJCC v7">Stage III Esophageal Squamous Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/1661161" ref="tree=MeSH" title="MedGen record for Stage IV Esophageal Squamous Cell Carcinoma AJCC v7">Stage IV Esophageal Squamous Cell Carcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1613217" ref="tree=MeSH" title="MedGen record for Esophageal Squamous Cell Carcinoma by AJCC v8 Stage">Esophageal Squamous Cell Carcinoma by AJCC v8 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/1623902" ref="tree=MeSH" title="MedGen record for Esophageal Squamous Cell Carcinoma by AJCC v8 Clinical Stage">Esophageal Squamous Cell Carcinoma by AJCC v8 Clinical Stage</a></span></li><li><span class="TLline"><a href="/medgen/1617526" ref="tree=MeSH" title="MedGen record for Esophageal Squamous Cell Carcinoma by AJCC v8 Pathologic Stage">Esophageal Squamous Cell Carcinoma by AJCC v8 Pathologic Stage</a></span></li><li><span class="TLline"><a href="/medgen/1614636" ref="tree=MeSH" title="MedGen record for Esophageal Squamous Cell Carcinoma by AJCC v8 Postneoadjuvant Therapy Stage">Esophageal Squamous Cell Carcinoma by AJCC v8 Postneoadjuvant Therapy Stage</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/459480" ref="tree=MeSH" title="MedGen record for Esophageal Well Differentiated Squamous Cell Carcinoma">Esophageal Well Differentiated Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1792372" ref="tree=MeSH" title="MedGen record for Esophageal Carcinoma Cuniculatum">Esophageal Carcinoma Cuniculatum</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/272594" ref="tree=MeSH" title="MedGen record for Esophagus verrucous carcinoma">Esophagus verrucous carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/232618" ref="tree=MeSH" title="MedGen record for Human Papillomavirus-Related Esophageal Squamous Cell Carcinoma">Human Papillomavirus-Related Esophageal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/222971" ref="tree=MeSH" title="MedGen record for Metastatic Esophageal Squamous Cell Carcinoma">Metastatic Esophageal Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1757946" ref="tree=MeSH" title="MedGen record for Advanced Esophageal Squamous Cell Carcinoma">Advanced Esophageal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1745399" ref="tree=MeSH" title="MedGen record for Locally Advanced Esophageal Squamous Cell Carcinoma">Locally Advanced Esophageal Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/163455" ref="tree=MeSH" title="MedGen record for Recurrent Esophageal Squamous Cell Carcinoma">Recurrent Esophageal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1734187" ref="tree=MeSH" title="MedGen record for Refractory Esophageal Squamous Cell Carcinoma">Refractory Esophageal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1665515" ref="tree=MeSH" title="MedGen record for Thoracic Esophagus Squamous Cell Carcinoma">Thoracic Esophagus Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1723894" ref="tree=MeSH" title="MedGen record for Unresectable Esophageal Squamous Cell Carcinoma">Unresectable Esophageal Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/234262" ref="tree=MeSH" title="MedGen record for Fallopian tube squamous cell carcinoma">Fallopian tube squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/83539" ref="tree=MeSH" title="MedGen record for Gallbladder squamous cell carcinoma">Gallbladder squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/234302" ref="tree=MeSH" title="MedGen record for Gastric squamous cell carcinoma">Gastric squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1668789" ref="tree=MeSH" title="MedGen record for Gastric Cardia Squamous Cell Carcinoma">Gastric Cardia Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1681281" ref="tree=MeSH" title="MedGen record for Human Papillomavirus-Independent Squamous Cell Carcinoma">Human Papillomavirus-Independent Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1793156" ref="tree=MeSH" title="MedGen record for Human Papillomavirus-Independent Vaginal Squamous Cell Carcinoma">Human Papillomavirus-Independent Vaginal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1793789" ref="tree=MeSH" title="MedGen record for Human Papillomavirus-Independent Vulvar Squamous Cell Carcinoma">Human Papillomavirus-Independent Vulvar Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1755712" ref="tree=MeSH" title="MedGen record for Oropharyngeal Human Papillomavirus-Independent Squamous Cell Carcinoma">Oropharyngeal Human Papillomavirus-Independent Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/272726" ref="tree=MeSH" title="MedGen record for Human papillomavirus-related squamous cell carcinoma">Human papillomavirus-related squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1769546" ref="tree=MeSH" title="MedGen record for Human Papillomavirus-Related Mucosal Head and Neck Squamous Cell Carcinoma">Human Papillomavirus-Related Mucosal Head and Neck Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/415751" ref="tree=MeSH" title="MedGen record for Oropharyngeal Human Papillomavirus-Related Squamous Cell Carcinoma">Oropharyngeal Human Papillomavirus-Related Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1739108" ref="tree=MeSH" title="MedGen record for Sinonasal Human Papillomavirus-Related Multiphenotypic Carcinoma">Sinonasal Human Papillomavirus-Related Multiphenotypic Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/235178" ref="tree=MeSH" title="MedGen record for Human papillomavirus-related penile squamous cell carcinoma">Human papillomavirus-related penile squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1685530" ref="tree=MeSH" title="MedGen record for Penile Clear Cell Squamous Cell Carcinoma">Penile Clear Cell Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1705111" ref="tree=MeSH" title="MedGen record for Penile Lymphoepithelioma-Like Carcinoma">Penile Lymphoepithelioma-Like Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1697123" ref="tree=MeSH" title="MedGen record for Penile Warty-Basaloid Carcinoma">Penile Warty-Basaloid Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/234997" ref="tree=MeSH" title="MedGen record for Warty carcinoma of the penis">Warty carcinoma of the penis</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/268874" ref="tree=MeSH" title="MedGen record for Human Papillomavirus-Related Urethral Squamous Cell Carcinoma">Human Papillomavirus-Related Urethral Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1793155" ref="tree=MeSH" title="MedGen record for Human Papillomavirus-Related Vaginal Squamous Cell Carcinoma">Human Papillomavirus-Related Vaginal Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/274383" ref="tree=MeSH" title="MedGen record for Vaginal Warty Carcinoma">Vaginal Warty Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/235179" ref="tree=MeSH" title="MedGen record for Human Papillomavirus-Related Verrucous Carcinoma">Human Papillomavirus-Related Verrucous Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/272727" ref="tree=MeSH" title="MedGen record for Human Papillomavirus-Related Vulvar Squamous Cell Carcinoma">Human Papillomavirus-Related Vulvar Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/275619" ref="tree=MeSH" title="MedGen record for Vulvar Warty Carcinoma">Vulvar Warty Carcinoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/137730" ref="tree=MeSH" title="MedGen record for Keratinizing squamous cell carcinoma">Keratinizing squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/91065" ref="tree=MeSH" title="MedGen record for Acantholytic squamous cell skin carcinoma">Acantholytic squamous cell skin carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/91064" ref="tree=MeSH" title="MedGen record for Clear cell squamous cell skin carcinoma">Clear cell squamous cell skin carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/317808" ref="tree=MeSH" title="MedGen record for Head and Neck Keratinizing Squamous Cell Carcinoma">Head and Neck Keratinizing Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/232478" ref="tree=MeSH" title="MedGen record for External ear squamous cell carcinoma">External ear squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/272785" ref="tree=MeSH" title="MedGen record for Keratinizing Primary Intraosseous Squamous Cell Carcinoma-Solid Type">Keratinizing Primary Intraosseous Squamous Cell Carcinoma-Solid Type</a></span></li><li><span class="TLline"><a href="/medgen/233191" ref="tree=MeSH" title="MedGen record for Middle ear squamous cell carcinoma">Middle ear squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1708895" ref="tree=MeSH" title="MedGen record for Nasopharyngeal Keratinizing Squamous Cell Carcinoma">Nasopharyngeal Keratinizing Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1752101" ref="tree=MeSH" title="MedGen record for Sinonasal Keratinizing Squamous Cell Carcinoma">Sinonasal Keratinizing Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/274269" ref="tree=MeSH" title="MedGen record for Large cell keratinizing variant squamous cell breast carcinoma">Large cell keratinizing variant squamous cell breast carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/318199" ref="tree=MeSH" title="MedGen record for Lung Squamous Cell Carcinoma, Clear Cell Variant">Lung Squamous Cell Carcinoma, Clear Cell Variant</a></span></li><li><span class="TLline"><a href="/medgen/318200" ref="tree=MeSH" title="MedGen record for Lung Squamous Cell Carcinoma, Papillary Variant">Lung Squamous Cell Carcinoma, Papillary Variant</a></span></li><li><span class="TLline"><a href="/medgen/354199" ref="tree=MeSH" title="MedGen record for Lung Squamous Cell Carcinoma, Small Cell Variant">Lung Squamous Cell Carcinoma, Small Cell Variant</a></span></li><li><span class="TLline"><a href="/medgen/233447" ref="tree=MeSH" title="MedGen record for Pseudovascular skin squamous cell carcinoma">Pseudovascular skin squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/220405" ref="tree=MeSH" title="MedGen record for Squamous Cell Carcinoma with Horn Formation">Squamous Cell Carcinoma with Horn Formation</a></span></li><li><span class="TLline"><a href="/medgen/311445" ref="tree=MeSH" title="MedGen record for Vaginal Keratinizing Squamous Cell Carcinoma">Vaginal Keratinizing Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/378346" ref="tree=MeSH" title="MedGen record for Vulvar keratinizing squamous cell carcinoma">Vulvar keratinizing squamous cell carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1783481" ref="tree=MeSH" title="MedGen record for Lacrimal Drainage System Squamous Cell Carcinoma">Lacrimal Drainage System Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1782058" ref="tree=MeSH" title="MedGen record for Lacrimal Drainage System Non-Keratinizing Squamous Cell Carcinoma">Lacrimal Drainage System Non-Keratinizing Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/90749" ref="tree=MeSH" title="MedGen record for Metastatic squamous cell carcinoma">Metastatic squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1706788" ref="tree=MeSH" title="MedGen record for Advanced Squamous Cell Carcinoma">Advanced Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1744469" ref="tree=MeSH" title="MedGen record for Advanced Anal Canal Squamous Cell Carcinoma">Advanced Anal Canal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1619962" ref="tree=MeSH" title="MedGen record for Advanced Head and Neck Squamous Cell Carcinoma">Advanced Head and Neck Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1756132" ref="tree=MeSH" title="MedGen record for Advanced Lung Squamous Cell Carcinoma">Advanced Lung Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1739737" ref="tree=MeSH" title="MedGen record for Advanced Rectal Squamous Cell Carcinoma">Advanced Rectal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1714296" ref="tree=MeSH" title="MedGen record for Advanced Skin Squamous Cell Carcinoma">Advanced Skin Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1793236" ref="tree=MeSH" title="MedGen record for Advanced Vaginal Squamous Cell Carcinoma">Advanced Vaginal Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/108290" ref="tree=MeSH" title="MedGen record for Disseminated Squamous Cell Carcinoma">Disseminated Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1651681" ref="tree=MeSH" title="MedGen record for Locally Advanced Squamous Cell Carcinoma">Locally Advanced Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1701136" ref="tree=MeSH" title="MedGen record for Locally Advanced Head and Neck Squamous Cell Carcinoma">Locally Advanced Head and Neck Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1684528" ref="tree=MeSH" title="MedGen record for Locally Advanced Lung Non-Small Cell Squamous Carcinoma">Locally Advanced Lung Non-Small Cell Squamous Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1761906" ref="tree=MeSH" title="MedGen record for Locally Advanced Rectal Squamous Cell Carcinoma">Locally Advanced Rectal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1656081" ref="tree=MeSH" title="MedGen record for Locally Advanced Skin Squamous Cell Carcinoma">Locally Advanced Skin Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1710496" ref="tree=MeSH" title="MedGen record for Locally Advanced Squamous Cell Carcinoma of Unknown Primary">Locally Advanced Squamous Cell Carcinoma of Unknown Primary</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/233188" ref="tree=MeSH" title="MedGen record for Metastatic Breast Squamous Cell Carcinoma">Metastatic Breast Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1660276" ref="tree=MeSH" title="MedGen record for Metastatic Head and Neck Squamous Cell Carcinoma">Metastatic Head and Neck Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1733748" ref="tree=MeSH" title="MedGen record for Metastatic Cutaneous Squamous Cell Carcinoma of the Head and Neck">Metastatic Cutaneous Squamous Cell Carcinoma of the Head and Neck</a></span></li><li><span class="TLline"><a href="/medgen/83649" ref="tree=MeSH" title="MedGen record for Metastatic Laryngeal Squamous Cell Carcinoma">Metastatic Laryngeal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1659624" ref="tree=MeSH" title="MedGen record for Metastatic Lip Squamous Cell Carcinoma">Metastatic Lip Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1670371" ref="tree=MeSH" title="MedGen record for Metastatic Oral Cavity Squamous Cell Carcinoma">Metastatic Oral Cavity Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1768945" ref="tree=MeSH" title="MedGen record for Metastatic Pharyngeal Squamous Cell Carcinoma">Metastatic Pharyngeal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1762905" ref="tree=MeSH" title="MedGen record for Metastatic Salivary Gland Squamous Cell Carcinoma">Metastatic Salivary Gland Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1701061" ref="tree=MeSH" title="MedGen record for Metastatic Sinonasal Squamous Cell Carcinoma">Metastatic Sinonasal Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/163176" ref="tree=MeSH" title="MedGen record for Metastatic Lung Squamous Cell Carcinoma">Metastatic Lung Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1679728" ref="tree=MeSH" title="MedGen record for Metastatic Lung Non-Small Cell Squamous Carcinoma">Metastatic Lung Non-Small Cell Squamous Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1639831" ref="tree=MeSH" title="MedGen record for Metastatic Skin Squamous Cell Carcinoma">Metastatic Skin Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1713699" ref="tree=MeSH" title="MedGen record for Recurrent Metastatic Skin Squamous Cell Carcinoma">Recurrent Metastatic Skin Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1676273" ref="tree=MeSH" title="MedGen record for Metastatic Squamous Cell Carcinoma in the Cervical Lymph Nodes">Metastatic Squamous Cell Carcinoma in the Cervical Lymph Nodes</a></span></li><li><span class="TLline"><a href="/medgen/1793235" ref="tree=MeSH" title="MedGen record for Metastatic Vaginal Squamous Cell Carcinoma">Metastatic Vaginal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1761005" ref="tree=MeSH" title="MedGen record for Metastatic Vulvar Squamous Cell Carcinoma">Metastatic Vulvar Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/76067" ref="tree=MeSH" title="MedGen record for Squamous Cell Carcinoma of Unknown Primary">Squamous Cell Carcinoma of Unknown Primary</a></span><ul><li><span class="TLline"><a href="/medgen/65078" ref="tree=MeSH" title="MedGen record for Neck Squamous Cell Carcinoma of Unknown Primary">Neck Squamous Cell Carcinoma of Unknown Primary</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/137733" ref="tree=MeSH" title="MedGen record for Microinvasive Squamous Cell Carcinoma">Microinvasive Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/90750" ref="tree=MeSH" title="MedGen record for Non-Keratinizing Large Cell Squamous Cell Carcinoma">Non-Keratinizing Large Cell Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/137731" ref="tree=MeSH" title="MedGen record for Non-Keratinizing Small Cell Squamous Cell Carcinoma">Non-Keratinizing Small Cell Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/76094" ref="tree=MeSH" title="MedGen record for Oropharyngeal squamous cell carcinoma">Oropharyngeal squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/124732" ref="tree=MeSH" title="MedGen record for Metastatic Oropharyngeal Squamous Cell Carcinoma">Metastatic Oropharyngeal Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1661808" ref="tree=MeSH" title="MedGen record for Advanced Oropharyngeal Squamous Cell Carcinoma">Advanced Oropharyngeal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1693245" ref="tree=MeSH" title="MedGen record for Locally Advanced Oropharyngeal Squamous Cell Carcinoma">Locally Advanced Oropharyngeal Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1636921" ref="tree=MeSH" title="MedGen record for Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma">Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/926082" ref="tree=MeSH" title="MedGen record for Oropharyngeal Poorly Differentiated Carcinoma">Oropharyngeal Poorly Differentiated Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/76095" ref="tree=MeSH" title="MedGen record for Oropharyngeal Undifferentiated Carcinoma">Oropharyngeal Undifferentiated Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/857327" ref="tree=MeSH" title="MedGen record for Recurrent Oropharyngeal Undifferentiated Carcinoma">Recurrent Oropharyngeal Undifferentiated Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/852487" ref="tree=MeSH" title="MedGen record for Stage I Oropharyngeal Undifferentiated Carcinoma AJCC v6 and v7">Stage I Oropharyngeal Undifferentiated Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/857132" ref="tree=MeSH" title="MedGen record for Stage II Oropharyngeal Undifferentiated Carcinoma AJCC v6 and v7">Stage II Oropharyngeal Undifferentiated Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/852488" ref="tree=MeSH" title="MedGen record for Stage III Oropharyngeal Undifferentiated Carcinoma AJCC v7">Stage III Oropharyngeal Undifferentiated Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/852489" ref="tree=MeSH" title="MedGen record for Stage IV Oropharyngeal Undifferentiated Carcinoma AJCC v7">Stage IV Oropharyngeal Undifferentiated Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/277822" ref="tree=MeSH" title="MedGen record for Tonsillar Undifferentiated Carcinoma">Tonsillar Undifferentiated Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/79109" ref="tree=MeSH" title="MedGen record for Recurrent Oropharyngeal Squamous Cell Carcinoma">Recurrent Oropharyngeal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1669285" ref="tree=MeSH" title="MedGen record for Refractory Oropharyngeal Squamous Cell Carcinoma">Refractory Oropharyngeal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1694101" ref="tree=MeSH" title="MedGen record for Resectable Oropharyngeal Squamous Cell Carcinoma">Resectable Oropharyngeal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/148181" ref="tree=MeSH" title="MedGen record for Soft Palate Squamous Cell Carcinoma">Soft Palate Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/163662" ref="tree=MeSH" title="MedGen record for Stage 0 Oropharyngeal Squamous Cell Carcinoma AJCC v6 and v7">Stage 0 Oropharyngeal Squamous Cell Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/76103" ref="tree=MeSH" title="MedGen record for Stage I Oropharyngeal Squamous Cell Carcinoma AJCC v6 and v7">Stage I Oropharyngeal Squamous Cell Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/83640" ref="tree=MeSH" title="MedGen record for Stage II Oropharyngeal Squamous Cell Carcinoma AJCC v6 and v7">Stage II Oropharyngeal Squamous Cell Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/124731" ref="tree=MeSH" title="MedGen record for Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7">Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/1669998" ref="tree=MeSH" title="MedGen record for Stage IV Oropharyngeal Squamous Cell Carcinoma AJCC v7">Stage IV Oropharyngeal Squamous Cell Carcinoma AJCC v7</a></span><ul><li><span class="TLline"><a href="/medgen/234870" ref="tree=MeSH" title="MedGen record for Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7">Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/234875" ref="tree=MeSH" title="MedGen record for Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7">Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/233529" ref="tree=MeSH" title="MedGen record for Stage IVC Oropharyngeal Squamous Cell Carcinoma AJCC v7">Stage IVC Oropharyngeal Squamous Cell Carcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/79101" ref="tree=MeSH" title="MedGen record for Tonsillar squamous cell carcinoma">Tonsillar squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1704184" ref="tree=MeSH" title="MedGen record for Unresectable Oropharyngeal Squamous Cell Carcinoma">Unresectable Oropharyngeal Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/384474" ref="tree=MeSH" title="MedGen record for Ovarian squamous cell carcinoma">Ovarian squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1791971" ref="tree=MeSH" title="MedGen record for Refractory Ovarian Squamous Cell Carcinoma">Refractory Ovarian Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/393937" ref="tree=MeSH" title="MedGen record for Pancreatic squamous cell carcinoma">Pancreatic squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/83115" ref="tree=MeSH" title="MedGen record for Papillary squamous carcinoma">Papillary squamous carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/473519" ref="tree=MeSH" title="MedGen record for Laryngeal Papillary Squamous Cell Carcinoma">Laryngeal Papillary Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/266084" ref="tree=MeSH" title="MedGen record for Non-Invasive Papillary Squamous Cell Carcinoma">Non-Invasive Papillary Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/236848" ref="tree=MeSH" title="MedGen record for Stage 0 Laryngeal Verrucous Carcinoma AJCC v6, v7, and v8">Stage 0 Laryngeal Verrucous Carcinoma AJCC v6, v7, and v8</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/235455" ref="tree=MeSH" title="MedGen record for Papillary carcinoma of the penis">Papillary carcinoma of the penis</a></span><ul><li><span class="TLline"><a href="/medgen/234477" ref="tree=MeSH" title="MedGen record for Penis verrucous carcinoma">Penis verrucous carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/925568" ref="tree=MeSH" title="MedGen record for Vaginal Papillary Carcinoma">Vaginal Papillary Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/60213" ref="tree=MeSH" title="MedGen record for Verrucous carcinoma">Verrucous carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/473018" ref="tree=MeSH" title="MedGen record for Buschke Lowenstein tumor">Buschke Lowenstein tumor</a></span></li><li><span class="TLline"><a href="/medgen/76097" ref="tree=MeSH" title="MedGen record for Larynx verrucous carcinoma">Larynx verrucous carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1718207" ref="tree=MeSH" title="MedGen record for Skin Verrucous Carcinoma">Skin Verrucous Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/274359" ref="tree=MeSH" title="MedGen record for Urethral verrucous carcinoma">Urethral verrucous carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/234984" ref="tree=MeSH" title="MedGen record for Vaginal Verrucous Carcinoma">Vaginal Verrucous Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/124716" ref="tree=MeSH" title="MedGen record for Verrucous carcinoma of oral cavity">Verrucous carcinoma of oral cavity</a></span></li><li><span class="TLline"><a href="/medgen/234482" ref="tree=MeSH" title="MedGen record for Vulva verrucous carcinoma">Vulva verrucous carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/757679" ref="tree=MeSH" title="MedGen record for Warty Carcinoma">Warty Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/273128" ref="tree=MeSH" title="MedGen record for Cervical Warty Carcinoma">Cervical Warty Carcinoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/1694695" ref="tree=MeSH" title="MedGen record for Paratesticular Squamous Cell Carcinoma">Paratesticular Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1704191" ref="tree=MeSH" title="MedGen record for Seminal Vesicle Squamous Cell Carcinoma">Seminal Vesicle Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/226996" ref="tree=MeSH" title="MedGen record for Prostate squamous cell carcinoma">Prostate squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1731648" ref="tree=MeSH" title="MedGen record for Pseudoglandular squamous cell carcinoma">Pseudoglandular squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/313337" ref="tree=MeSH" title="MedGen record for Laryngeal Acantholytic Squamous Cell Carcinoma">Laryngeal Acantholytic Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1699041" ref="tree=MeSH" title="MedGen record for Penile Pseudoglandular Carcinoma">Penile Pseudoglandular Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/930664" ref="tree=MeSH" title="MedGen record for Recurrent Squamous Cell Carcinoma">Recurrent Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1621629" ref="tree=MeSH" title="MedGen record for Recurrent Head and Neck Squamous Cell Carcinoma">Recurrent Head and Neck Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1784906" ref="tree=MeSH" title="MedGen record for Locally Recurrent Head and Neck Squamous Cell Carcinoma">Locally Recurrent Head and Neck Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1691326" ref="tree=MeSH" title="MedGen record for Recurrent Cutaneous Squamous Cell Carcinoma of the Head and Neck">Recurrent Cutaneous Squamous Cell Carcinoma of the Head and Neck</a></span></li><li><span class="TLline"><a href="/medgen/79114" ref="tree=MeSH" title="MedGen record for Recurrent Laryngeal Squamous Cell Carcinoma">Recurrent Laryngeal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/852486" ref="tree=MeSH" title="MedGen record for Recurrent Lip and Oral Cavity Squamous Cell Carcinoma">Recurrent Lip and Oral Cavity Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1753201" ref="tree=MeSH" title="MedGen record for Recurrent Pharyngeal Squamous Cell Carcinoma">Recurrent Pharyngeal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1730212" ref="tree=MeSH" title="MedGen record for Recurrent Salivary Gland Squamous Cell Carcinoma">Recurrent Salivary Gland Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/852494" ref="tree=MeSH" title="MedGen record for Recurrent Sinonasal Squamous Cell Carcinoma">Recurrent Sinonasal Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/163175" ref="tree=MeSH" title="MedGen record for Recurrent Lung Squamous Cell Carcinoma">Recurrent Lung Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1750219" ref="tree=MeSH" title="MedGen record for Recurrent Lung Non-Small Cell Squamous Carcinoma">Recurrent Lung Non-Small Cell Squamous Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/235540" ref="tree=MeSH" title="MedGen record for Recurrent Neck Squamous Cell Carcinoma of Unknown Primary">Recurrent Neck Squamous Cell Carcinoma of Unknown Primary</a></span></li><li><span class="TLline"><a href="/medgen/1639538" ref="tree=MeSH" title="MedGen record for Recurrent Skin Squamous Cell Carcinoma">Recurrent Skin Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1710789" ref="tree=MeSH" title="MedGen record for Locally Recurrent Skin Squamous Cell Carcinoma">Locally Recurrent Skin Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1740235" ref="tree=MeSH" title="MedGen record for Recurrent Vulvar Squamous Cell Carcinoma">Recurrent Vulvar Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1768820" ref="tree=MeSH" title="MedGen record for Refractory Squamous Cell Carcinoma">Refractory Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1655619" ref="tree=MeSH" title="MedGen record for Refractory Head and Neck Squamous Cell Carcinoma">Refractory Head and Neck Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1728246" ref="tree=MeSH" title="MedGen record for Refractory Cutaneous Squamous Cell Carcinoma of the Head and Neck">Refractory Cutaneous Squamous Cell Carcinoma of the Head and Neck</a></span></li><li><span class="TLline"><a href="/medgen/1665403" ref="tree=MeSH" title="MedGen record for Refractory Hypopharyngeal Squamous Cell Carcinoma">Refractory Hypopharyngeal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1654726" ref="tree=MeSH" title="MedGen record for Refractory Laryngeal Squamous Cell Carcinoma">Refractory Laryngeal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1650027" ref="tree=MeSH" title="MedGen record for Refractory Oral Cavity Squamous Cell Carcinoma">Refractory Oral Cavity Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1661272" ref="tree=MeSH" title="MedGen record for Refractory Sinonasal Squamous Cell Carcinoma">Refractory Sinonasal Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1743058" ref="tree=MeSH" title="MedGen record for Refractory Lung Squamous Cell Carcinoma">Refractory Lung Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1764028" ref="tree=MeSH" title="MedGen record for Refractory Lung Non-Small Cell Squamous Carcinoma">Refractory Lung Non-Small Cell Squamous Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1710593" ref="tree=MeSH" title="MedGen record for Refractory Skin Squamous Cell Carcinoma">Refractory Skin Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/66769" ref="tree=MeSH" title="MedGen record for Renal pelvis squamous cell carcinoma">Renal pelvis squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/87611" ref="tree=MeSH" title="MedGen record for Sarcomatoid squamous cell skin carcinoma">Sarcomatoid squamous cell skin carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/926567" ref="tree=MeSH" title="MedGen record for Gingival Spindle Cell Carcinoma">Gingival Spindle Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/310918" ref="tree=MeSH" title="MedGen record for Laryngeal Spindle Cell Squamous Carcinoma">Laryngeal Spindle Cell Squamous Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/235580" ref="tree=MeSH" title="MedGen record for Sarcomatoid penile squamous cell carcinoma">Sarcomatoid penile squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1734714" ref="tree=MeSH" title="MedGen record for Sinonasal Spindle Cell Squamous Carcinoma">Sinonasal Spindle Cell Squamous Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/274270" ref="tree=MeSH" title="MedGen record for Spindle cell variant squamous cell breast carcinoma">Spindle cell variant squamous cell breast carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/83116" ref="tree=MeSH" title="MedGen record for Squamous carcinoma in situ">Squamous carcinoma in situ</a></span><ul><li><span class="TLline"><a href="/medgen/1622616" ref="tree=MeSH" title="MedGen record for Clinical Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8">Clinical Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8</a></span></li><li><span class="TLline"><a href="/medgen/1625266" ref="tree=MeSH" title="MedGen record for Lung Squamous Cell Carcinoma In Situ">Lung Squamous Cell Carcinoma In Situ</a></span><ul><li><span class="TLline"><a href="/medgen/1620963" ref="tree=MeSH" title="MedGen record for Stage 0 Lung Squamous Cell Carcinoma AJCC v6 and v7">Stage 0 Lung Squamous Cell Carcinoma AJCC v6 and v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1619931" ref="tree=MeSH" title="MedGen record for Pathologic Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8">Pathologic Stage 0 Esophageal Squamous Cell Carcinoma AJCC v8</a></span></li><li><span class="TLline"><a href="/medgen/102309" ref="tree=MeSH" title="MedGen record for Penis carcinoma in situ">Penis carcinoma in situ</a></span></li><li><span class="TLline"><a href="/medgen/378389" ref="tree=MeSH" title="MedGen record for Skin squamous cell carcinoma in situ">Skin squamous cell carcinoma in situ</a></span></li><li><span class="TLline"><a href="/medgen/236845" ref="tree=MeSH" title="MedGen record for Squamous Cell Carcinoma In Situ of the Nipple">Squamous Cell Carcinoma In Situ of the Nipple</a></span></li><li><span class="TLline"><a href="/medgen/1623983" ref="tree=MeSH" title="MedGen record for Stage 0 Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8">Stage 0 Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8</a></span></li><li><span class="TLline"><a href="/medgen/1619618" ref="tree=MeSH" title="MedGen record for Stage 0 Laryngeal Squamous Cell Carcinoma AJCC v6, v7, and v8">Stage 0 Laryngeal Squamous Cell Carcinoma AJCC v6, v7, and v8</a></span><ul><li><span class="TLline"><a href="/medgen/1624733" ref="tree=MeSH" title="MedGen record for Stage 0 Epiglottic Carcinoma AJCC v6, v7, and v8">Stage 0 Epiglottic Carcinoma AJCC v6, v7, and v8</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/163659" ref="tree=MeSH" title="MedGen record for Stage 0 Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7">Stage 0 Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/57816" ref="tree=MeSH" title="MedGen record for Trachea carcinoma in situ">Trachea carcinoma in situ</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/209017" ref="tree=MeSH" title="MedGen record for Squamous cell bile duct carcinoma">Squamous cell bile duct carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/233465" ref="tree=MeSH" title="MedGen record for Squamous cell breast carcinoma">Squamous cell breast carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/274268" ref="tree=MeSH" title="MedGen record for Acantholytic variant squamous cell breast carcinoma">Acantholytic variant squamous cell breast carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/90751" ref="tree=MeSH" title="MedGen record for Squamous Cell Carcinoma In Situ with Questionable Stromal Invasion">Squamous Cell Carcinoma In Situ with Questionable Stromal Invasion</a></span></li><li><span class="TLline"><a href="/medgen/116057" ref="tree=MeSH" title="MedGen record for Squamous cell carcinoma of penis">Squamous cell carcinoma of penis</a></span></li><li><span class="TLline"><a href="/medgen/257911" ref="tree=MeSH" title="MedGen record for Squamous cell carcinoma of the head and neck">Squamous cell carcinoma of the head and neck</a></span><ul><li><span class="TLline"><a href="/medgen/1705140" ref="tree=MeSH" title="MedGen record for ASPH-Positive Head and Neck Squamous Cell Carcinoma">ASPH-Positive Head and Neck Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1614715" ref="tree=MeSH" title="MedGen record for Cutaneous Squamous Cell Carcinoma of the Head and Neck">Cutaneous Squamous Cell Carcinoma of the Head and Neck</a></span><ul><li><span class="TLline"><a href="/medgen/1617614" ref="tree=MeSH" title="MedGen record for Cutaneous Squamous Cell Carcinoma of the Head and Neck by AJCC v8 Stage">Cutaneous Squamous Cell Carcinoma of the Head and Neck by AJCC v8 Stage</a></span></li><li><span class="TLline"><a href="/medgen/1694931" ref="tree=MeSH" title="MedGen record for Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck">Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/83630" ref="tree=MeSH" title="MedGen record for Laryngeal squamous cell carcinoma">Laryngeal squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/76096" ref="tree=MeSH" title="MedGen record for Glottis squamous cell carcinoma">Glottis squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1620522" ref="tree=MeSH" title="MedGen record for Stage I Laryngeal Squamous Cell Carcinoma AJCC v6 and v7">Stage I Laryngeal Squamous Cell Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1624646" ref="tree=MeSH" title="MedGen record for Stage II Laryngeal Squamous Cell Carcinoma AJCC v6 and v7">Stage II Laryngeal Squamous Cell Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1620020" ref="tree=MeSH" title="MedGen record for Stage III Laryngeal Squamous Cell Carcinoma AJCC v6 and v7">Stage III Laryngeal Squamous Cell Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1656464" ref="tree=MeSH" title="MedGen record for Stage IV Laryngeal Squamous Cell Carcinoma AJCC v7">Stage IV Laryngeal Squamous Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/124720" ref="tree=MeSH" title="MedGen record for Subglottis squamous cell carcinoma">Subglottis squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/152890" ref="tree=MeSH" title="MedGen record for Supraglottis squamous cell carcinoma">Supraglottis squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1732482" ref="tree=MeSH" title="MedGen record for Unresectable Laryngeal Squamous Cell Carcinoma">Unresectable Laryngeal Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/124714" ref="tree=MeSH" title="MedGen record for Lip and oral cavity squamous cell carcinoma">Lip and oral cavity squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/108436" ref="tree=MeSH" title="MedGen record for Oral cavity squamous cell carcinoma">Oral cavity squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/79099" ref="tree=MeSH" title="MedGen record for Squamous cell carcinoma of lip">Squamous cell carcinoma of lip</a></span></li><li><span class="TLline"><a href="/medgen/852482" ref="tree=MeSH" title="MedGen record for Stage I Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7">Stage I Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/852483" ref="tree=MeSH" title="MedGen record for Stage II Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7">Stage II Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/852484" ref="tree=MeSH" title="MedGen record for Stage III Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7">Stage III Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/852485" ref="tree=MeSH" title="MedGen record for Stage IV Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7">Stage IV Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/124722" ref="tree=MeSH" title="MedGen record for Nasal cavity and paranasal sinus squamous cell carcinoma">Nasal cavity and paranasal sinus squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/79104" ref="tree=MeSH" title="MedGen record for Nasal cavity squamous cell carcinoma">Nasal cavity squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/83119" ref="tree=MeSH" title="MedGen record for Non-keratinizing sinonasal squamous cell carcinoma">Non-keratinizing sinonasal squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/79105" ref="tree=MeSH" title="MedGen record for Paranasal sinus squamous cell carcinoma">Paranasal sinus squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1625233" ref="tree=MeSH" title="MedGen record for Stage I Sinonasal Squamous Cell Carcinoma AJCC v6 and v7">Stage I Sinonasal Squamous Cell Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1611675" ref="tree=MeSH" title="MedGen record for Stage II Sinonasal Squamous Cell Carcinoma AJCC v6 and v7">Stage II Sinonasal Squamous Cell Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/1618753" ref="tree=MeSH" title="MedGen record for Stage III Sinonasal Squamous Cell Carcinoma AJCC v6 and v7">Stage III Sinonasal Squamous Cell Carcinoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/852493" ref="tree=MeSH" title="MedGen record for Stage IV Sinonasal Squamous Cell Carcinoma AJCC v7">Stage IV Sinonasal Squamous Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/1778363" ref="tree=MeSH" title="MedGen record for Unresectable Sinonasal Squamous Cell Carcinoma">Unresectable Sinonasal Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/728086" ref="tree=MeSH" title="MedGen record for Pharyngeal squamous cell carcinoma">Pharyngeal squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/79102" ref="tree=MeSH" title="MedGen record for Hypopharynx squamous cell carcinoma">Hypopharynx squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/76017" ref="tree=MeSH" title="MedGen record for Nasopharyngeal squamous cell carcinoma">Nasopharyngeal squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/233867" ref="tree=MeSH" title="MedGen record for Posterior Pharyngeal Wall Squamous Cell Carcinoma">Posterior Pharyngeal Wall Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1372955" ref="tree=MeSH" title="MedGen record for Resectable Head and Neck Squamous Cell Carcinoma">Resectable Head and Neck Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/83545" ref="tree=MeSH" title="MedGen record for Salivary gland squamous cell carcinoma">Salivary gland squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1793310" ref="tree=MeSH" title="MedGen record for Major Salivary Gland Squamous Cell Carcinoma">Major Salivary Gland Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/233712" ref="tree=MeSH" title="MedGen record for Minor Salivary Gland Squamous Cell Carcinoma">Minor Salivary Gland Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/417024" ref="tree=MeSH" title="MedGen record for Salivary Gland Poorly Differentiated Squamous Cell Carcinoma">Salivary Gland Poorly Differentiated Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1771591" ref="tree=MeSH" title="MedGen record for Unresectable Salivary Gland Squamous Cell Carcinoma">Unresectable Salivary Gland Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1613385" ref="tree=MeSH" title="MedGen record for Unresectable Head and Neck Squamous Cell Carcinoma">Unresectable Head and Neck Squamous Cell Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1777191" ref="tree=MeSH" title="MedGen record for Unresectable Hypopharyngeal Squamous Cell Carcinoma">Unresectable Hypopharyngeal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1737201" ref="tree=MeSH" title="MedGen record for Unresectable Nasopharyngeal Squamous Cell Carcinoma">Unresectable Nasopharyngeal Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1748904" ref="tree=MeSH" title="MedGen record for Unresectable Oral Cavity Squamous Cell Carcinoma">Unresectable Oral Cavity Squamous Cell Carcinoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/107512" ref="tree=MeSH" title="MedGen record for Squamous cell carcinoma of the skin">Squamous cell carcinoma of the skin</a></span><ul><li><span class="TLline"><a href="/medgen/1685245" ref="tree=MeSH" title="MedGen record for Hematologic Malignancy-Associated Skin Squamous Cell Carcinoma">Hematologic Malignancy-Associated Skin Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/5954" ref="tree=MeSH" title="MedGen record for Keratoacanthoma">Keratoacanthoma</a></span><ul><li><span class="TLline"><a href="/medgen/925539" ref="tree=MeSH" title="MedGen record for Vulvar Keratoacanthoma">Vulvar Keratoacanthoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/233265" ref="tree=MeSH" title="MedGen record for Old Burn Scar-Related Skin Squamous Cell Carcinoma">Old Burn Scar-Related Skin Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1746207" ref="tree=MeSH" title="MedGen record for Resectable Skin Squamous Cell Carcinoma">Resectable Skin Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/138101" ref="tree=MeSH" title="MedGen record for Scrotum squamous cell carcinoma">Scrotum squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/699346" ref="tree=MeSH" title="MedGen record for Skin Lymphoepithelial Carcinoma">Skin Lymphoepithelial Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1711087" ref="tree=MeSH" title="MedGen record for Skin Squamous Cell Carcinoma with Osteoclast-Like Giant Cells">Skin Squamous Cell Carcinoma with Osteoclast-Like Giant Cells</a></span></li><li><span class="TLline"><a href="/medgen/1710338" ref="tree=MeSH" title="MedGen record for Skin Squamous Cell Carcinoma with Sarcomatoid Differentiation">Skin Squamous Cell Carcinoma with Sarcomatoid Differentiation</a></span></li><li><span class="TLline"><a href="/medgen/234798" ref="tree=MeSH" title="MedGen record for Solar Radiation-Related Skin Squamous Cell Carcinoma">Solar Radiation-Related Skin Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/234962" ref="tree=MeSH" title="MedGen record for Transplant-Related Skin Squamous Cell Carcinoma">Transplant-Related Skin Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1675867" ref="tree=MeSH" title="MedGen record for Unresectable Skin Squamous Cell Carcinoma">Unresectable Skin Squamous Cell Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/313711" ref="tree=MeSH" title="MedGen record for Squamous cell carcinoma of the small intestine">Squamous cell carcinoma of the small intestine</a></span></li><li><span class="TLline"><a href="/medgen/79201" ref="tree=MeSH" title="MedGen record for Squamous cell carcinoma of the vulva">Squamous cell carcinoma of the vulva</a></span><ul><li><span class="TLline"><a href="/medgen/307249" ref="tree=MeSH" title="MedGen record for Bartholin gland squamous cell carcinoma">Bartholin gland squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1748386" ref="tree=MeSH" title="MedGen record for Unresectable Vulvar Squamous Cell Carcinoma">Unresectable Vulvar Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/311488" ref="tree=MeSH" title="MedGen record for Vulvar non-keratinizing squamous cell carcinoma">Vulvar non-keratinizing squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/311489" ref="tree=MeSH" title="MedGen record for Vulvar Squamous Cell Carcinoma with Tumor Giant Cells">Vulvar Squamous Cell Carcinoma with Tumor Giant Cells</a></span></li><li><span class="TLline"><a href="/medgen/1793788" ref="tree=MeSH" title="MedGen record for Vulvar Squamous Cell Carcinoma, Not Otherwise Specified">Vulvar Squamous Cell Carcinoma, Not Otherwise Specified</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/226829" ref="tree=MeSH" title="MedGen record for Squamous Cell Carcinoma, Clear Cell Type">Squamous Cell Carcinoma, Clear Cell Type</a></span></li><li><span class="TLline"><a href="/medgen/56202" ref="tree=MeSH" title="MedGen record for Squamous cell lung carcinoma">Squamous cell lung carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1625078" ref="tree=MeSH" title="MedGen record for Lung Keratinizing Squamous Cell Carcinoma">Lung Keratinizing Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1611891" ref="tree=MeSH" title="MedGen record for Lung Non-Keratinizing Squamous Cell Carcinoma">Lung Non-Keratinizing Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/235400" ref="tree=MeSH" title="MedGen record for Lung occult squamous cell carcinoma">Lung occult squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1614560" ref="tree=MeSH" title="MedGen record for Lung Squamous Cell Carcinoma by AJCC v7 Stage">Lung Squamous Cell Carcinoma by AJCC v7 Stage</a></span><ul><li><span class="TLline"><a href="/medgen/208937" ref="tree=MeSH" title="MedGen record for Stage I Lung Squamous Cell Carcinoma AJCC v7">Stage I Lung Squamous Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/167749" ref="tree=MeSH" title="MedGen record for Stage II Lung Squamous Cell Carcinoma AJCC v7">Stage II Lung Squamous Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/167750" ref="tree=MeSH" title="MedGen record for Stage III Lung Squamous Cell Carcinoma AJCC v7">Stage III Lung Squamous Cell Carcinoma AJCC v7</a></span></li><li><span class="TLline"><a href="/medgen/1663964" ref="tree=MeSH" title="MedGen record for Stage IV Lung Squamous Cell Carcinoma AJCC v7">Stage IV Lung Squamous Cell Carcinoma AJCC v7</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1383559" ref="tree=MeSH" title="MedGen record for Non-small cell squamous lung carcinoma">Non-small cell squamous lung carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1769067" ref="tree=MeSH" title="MedGen record for Unresectable Lung Non-Small Cell Squamous Carcinoma">Unresectable Lung Non-Small Cell Squamous Carcinoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/234814" ref="tree=MeSH" title="MedGen record for Thymus squamous cell carcinoma">Thymus squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/328050" ref="tree=MeSH" title="MedGen record for Thyroid gland squamous cell carcinoma">Thyroid gland squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/91059" ref="tree=MeSH" title="MedGen record for Trachea squamous cell carcinoma">Trachea squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1650761" ref="tree=MeSH" title="MedGen record for Transplant-Related Squamous Cell Carcinoma">Transplant-Related Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/237032" ref="tree=MeSH" title="MedGen record for Ureter squamous cell carcinoma">Ureter squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/234975" ref="tree=MeSH" title="MedGen record for Urethra squamous cell carcinoma">Urethra squamous cell carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/66775" ref="tree=MeSH" title="MedGen record for Vaginal squamous cell carcinoma">Vaginal squamous cell carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1793158" ref="tree=MeSH" title="MedGen record for Advanced Vaginal Squamous Cell Carcinoma, Not Otherwise Specified">Advanced Vaginal Squamous Cell Carcinoma, Not Otherwise Specified</a></span></li><li><span class="TLline"><a href="/medgen/276953" ref="tree=MeSH" title="MedGen record for Vaginal Non-Keratinizing Squamous Cell Carcinoma">Vaginal Non-Keratinizing Squamous Cell Carcinoma</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_112">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="divPopper rprt" id="rdis_2685"><div><strong>Bloom syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>2685</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information."><span class="highlight" style="background-color:">C0005859</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Bloom syndrome (BSyn) is characterized by severe pre- and postnatal growth deficiency, immune abnormalities, sensitivity to sunlight, insulin resistance, and a high risk for many cancers that occur at an early age. Despite their very small head circumference, most affected individuals have normal intellectual ability. Women may be fertile but often have early menopause, and men tend to be infertile, with only one confirmed case of paternity. Serious medical complications that are more common than in the general population and that also appear at unusually early ages include cancer of a wide variety of types and anatomic sites, diabetes mellitus as a result of insulin resistance, chronic obstructive pulmonary disease, and hypothyroidism.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/2685">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_36311"><div><strong>Recessive dystrophic epidermolysis bullosa</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>36311</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0079474</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Dystrophic epidermolysis bullosa (DEB) is a genetic skin disorder affecting skin and nails that usually presents at birth. DEB is divided into two major types depending on inheritance pattern: recessive dystrophic epidermolysis bullosa (RDEB) and dominant dystrophic epidermolysis bullosa (DDEB). Each type is further divided into multiple clinical subtypes. Absence of a known family history of DEB does not preclude the diagnosis. Clinical findings in severe generalized RDEB include skin fragility manifest by blistering with minimal trauma that heals with milia and scarring. Blistering and erosions affecting the whole body may be present in the neonatal period. Oral involvement may lead to mouth blistering, fusion of the tongue to the floor of the mouth, and progressive diminution of the size of the oral cavity. Esophageal erosions can lead to webs and strictures that can cause severe dysphagia. Consequently, malnutrition and vitamin and mineral deficiency may lead to growth restriction in young children. Corneal erosions can lead to scarring and loss of vision. Blistering of the hands and feet followed by scarring fuses the digits into "mitten" hands and feet, with contractures and pseudosyndactyly. The lifetime risk of aggressive squamous cell carcinoma is higher than 90%. In contrast, the blistering in the less severe forms of RDEB may be localized to hands, feet, knees, and elbows with or without involvement of flexural areas and the trunk, and without the mutilating scarring seen in severe generalized RDEB. In DDEB, blistering is often mild and limited to hands, feet, knees, and elbows, but nonetheless heals with scarring. Dystrophic nails, especially toenails, are common and may be the only manifestation of DDEB.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/36311">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_120536"><div><strong>Autosomal dominant keratitis-ichthyosis-hearing loss syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>120536</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0265336</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Keratitis-ichthyosis-deafness (KID) syndrome is a rare ectodermal dysplasia characterized by sensorineural hearing loss, photophobia and corneal vascularization, hyperkeratosis of the palms and soles, erythrokeratoderma, follicular hyperkeratosis, and recurrent bacterial and fungal infections. A subset of patients with KID may develop multiple cystic pilar tumors, which are prone to malignant transformation and metastasis (Nyquist et al., 2007).&#13; Vohwinkel syndrome (124500) is an allelic disorder involving congenital deafness with keratopachydermia and constrictions of fingers and toes. Another similar disorder caused by mutation in GJB2 is palmoplantar keratoderma with deafness (148350).&#13; Genetic Heterogeneity of Keratitis-Ichthyosis-Deafness Syndrome&#13; An autosomal recessive form of KID syndrome (KIDAR; 242150) is caused by mutation in the AP1B1 gene (600157) on chromosome 22q12.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/120536">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_120612"><div><strong>Xeroderma pigmentosum, group F</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>120612</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0268140</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Congenital Abnormality</dd></dl></div></div></div>
<div class="spaceAbove">Xeroderma pigmentosum (XP) is characterized by: Acute sun sensitivity (severe sunburn with blistering, persistent erythema on minimal sun exposure) with marked freckle-like pigmentation of the face before age two years; Sunlight-induced ocular involvement (photophobia, severe keratitis, atrophy of the skin of the lids, ocular surface neoplasms); Greatly increased risk of sunlight-induced cutaneous neoplasms (basal cell carcinoma, squamous cell carcinoma, melanoma) within the first decade of life. Approximately 25% of affected individuals have neurologic manifestations (acquired microcephaly, diminished or absent deep tendon stretch reflexes, progressive sensorineural hearing loss, progressive cognitive impairment, and ataxia). The most common causes of death are skin cancer, neurologic degeneration, and internal cancer. The median age at death in persons with XP with neurodegeneration (29 years) was found to be younger than that in persons with XP without neurodegeneration (37 years).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/120612">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_216941"><div><strong>Dyskeratosis congenita, X-linked</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>216941</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1148551</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Dyskeratosis congenita and related telomere biology disorders (DC/TBD) are caused by impaired telomere maintenance resulting in short or very short telomeres. The phenotypic spectrum of telomere biology disorders is broad and includes individuals with classic dyskeratosis congenita (DC) as well as those with very short telomeres and an isolated physical finding. Classic DC is characterized by a triad of dysplastic nails, lacy reticular pigmentation of the upper chest and/or neck, and oral leukoplakia, although this may not be present in all individuals. People with DC/TBD are at increased risk for progressive bone marrow failure (BMF), myelodysplastic syndrome or acute myelogenous leukemia, solid tumors (usually squamous cell carcinoma of the head/neck or anogenital cancer), and pulmonary fibrosis. Other findings can include eye abnormalities (epiphora, blepharitis, sparse eyelashes, ectropion, entropion, trichiasis), taurodontism, liver disease, gastrointestinal telangiectasias, and avascular necrosis of the hips or shoulders. Although most persons with DC/TBD have normal psychomotor development and normal neurologic function, significant developmental delay is present in both forms; additional findings include cerebellar hypoplasia (Hoyeraal Hreidarsson syndrome) and bilateral exudative retinopathy and intracranial calcifications (Revesz syndrome and Coats plus syndrome). Onset and progression of manifestations of DC/TBD vary: at the mild end of the spectrum are those who have only minimal physical findings with normal bone marrow function, and at the severe end are those who have the diagnostic triad and early-onset BMF.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/216941">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_257911"><div><strong>Squamous cell carcinoma of the head and neck</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>257911</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1168401</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
<div class="spaceAbove">Squamous cell carcinoma is a cancer that arises from particular cells called squamous cells. Squamous cells are found in the outer layer of skin and in the mucous membranes, which are the moist tissues that line body cavities such as the airways and intestines. Head and neck squamous cell carcinoma (HNSCC) develops in the mucous membranes of the mouth, nose, and throat.\n\nHNSCC is classified by its location: it can occur in the mouth (oral cavity), the middle part of the throat near the mouth (oropharynx), the space behind the nose (nasal cavity and paranasal sinuses), the upper part of the throat near the nasal cavity (nasopharynx), the voicebox (larynx), or the lower part of the throat near the larynx (hypopharynx). Depending on the location, the cancer can cause abnormal patches or open sores (ulcers) in the mouth and throat, unusual bleeding or pain in the mouth, sinus congestion that does not clear, sore throat, earache, pain when swallowing or difficulty swallowing, a hoarse voice, difficulty breathing, or enlarged lymph nodes.\n\nHNSCC can spread (metastasize) to other parts of the body, such as the lymph nodes or lungs. If it spreads, the cancer has a worse prognosis and can be fatal. About half of affected individuals survive more than five years after diagnosis.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/257911">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_325450"><div><strong>Melanoma-pancreatic cancer syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>325450</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1838547</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Melanoma-pancreatic cancer syndrome is an inherited cancer predisposition syndrome in which mutation carriers have an increased risk of developing malignant melanoma and/or pancreatic cancer. Mutation carriers within families may develop either or both types of cancer (summary by Harinck et al., 2012).&#13; For background and phenotypic information on malignant melanoma and pancreatic cancer, see 155600 and 260350, respectively.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/325450">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_376352"><div><strong>Xeroderma pigmentosum variant type</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>376352</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1848410</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Xeroderma pigmentosum (XP) is characterized by: Acute sun sensitivity (severe sunburn with blistering, persistent erythema on minimal sun exposure) with marked freckle-like pigmentation of the face before age two years; Sunlight-induced ocular involvement (photophobia, severe keratitis, atrophy of the skin of the lids, ocular surface neoplasms); Greatly increased risk of sunlight-induced cutaneous neoplasms (basal cell carcinoma, squamous cell carcinoma, melanoma) within the first decade of life. Approximately 25% of affected individuals have neurologic manifestations (acquired microcephaly, diminished or absent deep tendon stretch reflexes, progressive sensorineural hearing loss, progressive cognitive impairment, and ataxia). The most common causes of death are skin cancer, neurologic degeneration, and internal cancer. The median age at death in persons with XP with neurodegeneration (29 years) was found to be younger than that in persons with XP without neurodegeneration (37 years).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/376352">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_347366"><div><strong>SchC6pf-Schulz-Passarge syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>347366</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1857069</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Schopf-Schulz-Passarge syndrome (SSPS) is an autosomal recessive disorder characterized by a constellation of multiple eyelid cysts, hypodontia, hypotrichosis, palmoplantar hyperkeratosis, and onychodystrophy (summary by Mallaiah and Dickinson, 2001).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/347366">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_355410"><div><strong>Ichthyosis, hystrix-like, with hearing loss</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>355410</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1865234</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Hystrix-like ichthyosis with deafness (HID) syndrome is an autosomal dominant keratinizing disorder characterized by sensorineural deafness and spiky hyperkeratosis affecting the entire skin. Erythroderma appears shortly after birth. After the first year of life, spiky and cobblestone-like hyperkeratosis develops, covering the entire skin surface. Palms and soles are only mildly affected. Scarring alopecia may be present (summary by Van Geel et al., 2002).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/355410">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_355730"><div><strong>Trichothiodystrophy 1, photosensitive</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>355730</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1866504</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Trichothiodystrophy is also associated with recurrent infections, particularly respiratory infections, which can be life-threatening. People with trichothiodystrophy may have abnormal red blood cells, including red blood cells that are smaller than normal. They may also have elevated levels of a type of hemoglobin called A2, which is a protein found in red blood cells. Other features of trichothiodystrophy can include dry, scaly skin (ichthyosis); abnormalities of the fingernails and toenails; clouding of the lens in both eyes from birth (congenital cataracts); poor coordination; and skeletal abnormalities including degeneration of both hips at an early age.\n\nAbout half of all people with trichothiodystrophy have a photosensitive form of the disorder, which causes them to be extremely sensitive to ultraviolet (UV) rays from sunlight. They develop a severe sunburn after spending just a few minutes in the sun. However, for reasons that are unclear, they do not develop other sun-related problems such as excessive freckling of the skin or an increased risk of skin cancer. Many people with trichothiodystrophy report that they do not sweat.\n\nIntellectual disability and delayed development are common in people with trichothiodystrophy, although most affected individuals are highly social with an outgoing and engaging personality. Some people with trichothiodystrophy have brain abnormalities that can be seen with imaging tests. A common neurological feature of this disorder is impaired myelin production (dysmyelination). Myelin is a fatty substance that insulates nerve cells and promotes the rapid transmission of nerve impulses.\n\nMothers of children with trichothiodystrophy may experience problems during pregnancy including pregnancy-induced high blood pressure (preeclampsia) and a related condition called HELLP syndrome that can damage the liver. Babies with trichothiodystrophy are at increased risk of premature birth, low birth weight, and slow growth. Most children with trichothiodystrophy have short stature compared to others their age. \n\nThe signs and symptoms of trichothiodystrophy vary widely. Mild cases may involve only the hair. More severe cases also cause delayed development, significant intellectual disability, and recurrent infections; severely affected individuals may survive only into infancy or early childhood.\n\nIn people with trichothiodystrophy, tests show that the hair is lacking sulfur-containing proteins that normally gives hair its strength. A cross section of a cut hair shows alternating light and dark banding that has been described as a "tiger tail."\n\nTrichothiodystrophy, commonly called TTD, is a rare inherited condition that affects many parts of the body. The hallmark of this condition is hair that is sparse and easily broken. </div>
<div class="spaceAbove nowrap">See: <a href="/medgen/355730">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_462387"><div><strong>Acne inversa, familial, 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>462387</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C3151037</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Acne inversa is a chronic inflammatory disease of the hair follicles whose characteristic features include draining sinuses, painful skin abscesses, and disfiguring scars. Manifestations typically appear after puberty. Familial acne inversa is genetically heterogeneous (summary by Wang et al., 2010). Some patients with PSENEN-associated acne inversa also exhibit reticulate hyperpigmentation consistent with Dowling-Degos disease (DDD; see 179850) (Zhou et al., 2016).&#13; For a general phenotypic description and a discussion of genetic heterogeneity of acne inversa, see 142690.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/462387">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_854020"><div><strong>Fanconi anemia complementation group P</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>854020</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C3469542</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Fanconi anemia (FA) is characterized by physical abnormalities, bone marrow failure, and increased risk for malignancy. Physical abnormalities, present in approximately 75% of affected individuals, include one or more of the following: short stature, abnormal skin pigmentation, skeletal malformations of the upper and/or lower limbs, microcephaly, and ophthalmic and genitourinary tract anomalies. Progressive bone marrow failure with pancytopenia typically presents in the first decade, often initially with thrombocytopenia or leukopenia. The incidence of acute myeloid leukemia is 13% by age 50 years. Solid tumors – particularly of the head and neck, skin, and genitourinary tract – are more common in individuals with FA.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/854020">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_815206"><div><strong>Corneal intraepithelial dyskeratosis-palmoplantar hyperkeratosis-laryngeal dyskeratosis syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>815206</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C3808876</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
<div class="spaceAbove">Multiple self-healing palmoplantar carcinoma (MSPC) is characterized by recurrent keratoacanthomas in palmoplantar skin as well as in conjunctival and corneal epithelia. In addition, patients experience a high susceptibility to malignant squamous cell carcinoma (summary by Zhong et al., 2016).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/815206">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1648410"><div><strong>Combined immunodeficiency due to DOCK8 deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1648410</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C4722305</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Hyper-IgE syndrome-2 with recurrent infections (HIES2) is an autosomal recessive immunologic disorder characterized by recurrent staphylococcal infections of the skin and respiratory tract, eczema, elevated serum immunoglobulin E, and hypereosinophilia. It is distinguished from autosomal dominant HIES1 (147060) by the lack of connective tissue and skeletal involvement (Renner et al., 2004).&#13; For a discussion of genetic heterogeneity of hyper-IgE syndrome, see 147060.&#13; See also TYK2 deficiency (611521), a clinically distinct disease entity that includes characteristic features of both autosomal recessive HIES2 and mendelian susceptibility to mycobacterial disease (MSMD; 209950) (Minegishi et al., 2006).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1648410">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1648390"><div><strong>Epidermodysplasia verruciformis, susceptibility to, 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1648390</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C4748876</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
<div class="spaceAbove">Epidermodysplasia verruciformis-3 (EV3) is characterized by onset in childhood or early adulthood of persistent disseminated flat warts and pityriasis versicolor-like lesions of the skin that are induced by cutaneous human papillomaviruses (HPVs) of the beta genus. Some patients develop nonmelanoma skin cancer, particularly on areas of the body exposed to the sun. Patients are otherwise healthy and normally resistant to other microorganisms, including other viruses and skintropic pathogens, and even all other cutaneous and mucosal HPVs (de Jong et al., 2018).&#13; For a discussion of genetic heterogeneity of susceptibility to epidermodysplasia verruciformis, see EV1 (226400).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1648390">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1678330"><div><strong>Cancer, alopecia, pigment dyscrasia, onychodystrophy, and keratoderma</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1678330</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C5193062</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">CAPOK syndrome (CAPOK) is characterized by onset of symptoms in the first year of life, with the development of progressive alopecia, hypo- and hyperpigmented macular skin lesions, palmoplantar keratoderma, and nail dystrophy. Beginning in the third decade of life, patients develop recurrent squamous cell carcinomas. Some patients may have brittle teeth resulting in tooth loss, and multinodular goiter has been observed (Courcet et al., 2015).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1678330">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1684753"><div><strong>Rothmund-Thomson syndrome type 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1684753</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C5203410</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Rothmund-Thomson syndrome (RTS) is characterized by a rash that progresses to poikiloderma; sparse hair, eyelashes, and/or eyebrows; small size; skeletal and dental abnormalities; juvenile cataracts; and an increased risk for cancer, especially osteosarcoma. A variety of benign and malignant hematologic abnormalities have been reported in affected individuals. The rash of RTS typically develops between ages three and six months (occasionally as late as age two years) as erythema, swelling, and blistering on the face, subsequently spreading to the buttocks and extremities. The rash evolves over months to years into the chronic pattern of reticulated hypo- and hyperpigmentation, telangiectasias, and punctate atrophy (collectively known as poikiloderma) that persist throughout life. Hyperkeratotic lesions occur in approximately one third of individuals. Skeletal abnormalities can include radial ray defects, ulnar defects, absent or hypoplastic patella, and osteopenia.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1684753">Condition Record</a></div></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_462387" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Acne inversa, familial, 2</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_120536" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Autosomal dominant keratitis-ichthyosis-hearing loss syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_2685" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Bloom syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1678330" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cancer, alopecia, pigment dyscrasia, onychodystrophy, and keratoderma</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1648410" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Combined immunodeficiency due to DOCK8 deficiency</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (18)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_815206" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Corneal intraepithelial dyskeratosis-palmoplantar hyperkeratosis-laryngeal dyskeratosis syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_216941" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Dyskeratosis congenita, X-linked</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1648390" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Epidermodysplasia verruciformis, susceptibility to, 3</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_854020" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Fanconi anemia complementation group P</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_355410" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Ichthyosis, hystrix-like, with hearing loss</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_325450" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Melanoma-pancreatic cancer syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_36311" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Recessive dystrophic epidermolysis bullosa</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1684753" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Rothmund-Thomson syndrome type 2</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_347366" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">SchC6pf-Schulz-Passarge syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_257911" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Squamous cell carcinoma of the head and neck</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_355730" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Trichothiodystrophy 1, photosensitive</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_376352" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Xeroderma pigmentosum variant type</a></div>
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</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/37658764">International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kuan EC,
Wang EW,
Adappa ND,
Beswick DM,
London NR Jr,
Su SY,
Wang MB,
Abuzeid WM,
Alexiev B,
Alt JA,
Antognoni P,
Alonso-Basanta M,
Batra PS,
Bhayani M,
Bell D,
Bernal-Sprekelsen M,
Betz CS,
Blay JY,
Bleier BS,
Bonilla-Velez J,
Callejas C,
Carrau RL,
Casiano RR,
Castelnuovo P,
Chandra RK,
Chatzinakis V,
Chen SB,
Chiu AG,
Choby G,
Chowdhury NI,
Citardi MJ,
Cohen MA,
Dagan R,
Dalfino G,
Dallan I,
Dassi CS,
de Almeida J,
Dei Tos AP,
DelGaudio JM,
Ebert CS,
El-Sayed IH,
Eloy JA,
Evans JJ,
Fang CH,
Farrell NF,
Ferrari M,
Fischbein N,
Folbe A,
Fokkens WJ,
Fox MG,
Lund VJ,
Gallia GL,
Gardner PA,
Geltzeiler M,
Georgalas C,
Getz AE,
Govindaraj S,
Gray ST,
Grayson JW,
Gross BA,
Grube JG,
Guo R,
Ha PK,
Halderman AA,
Hanna EY,
Harvey RJ,
Hernandez SC,
Holtzman AL,
Hopkins C,
Huang Z,
Huang Z,
Humphreys IM,
Hwang PH,
Iloreta AM,
Ishii M,
Ivan ME,
Jafari A,
Kennedy DW,
Khan M,
Kimple AJ,
Kingdom TT,
Knisely A,
Kuo YJ,
Lal D,
Lamarre ED,
Lan MY,
Le H,
Lechner M,
Lee NY,
Lee JK,
Lee VH,
Levine CG,
Lin JC,
Lin DT,
Lobo BC,
Locke T,
Luong AU,
Magliocca KR,
Markovic SN,
Matnjani G,
McKean EL,
Meço C,
Mendenhall WM,
Michel L,
Na'ara S,
Nicolai P,
Nuss DW,
Nyquist GG,
Oakley GM,
Omura K,
Orlandi RR,
Otori N,
Papagiannopoulos P,
Patel ZM,
Pfister DG,
Phan J,
Psaltis AJ,
Rabinowitz MR,
Ramanathan M Jr,
Rimmer R,
Rosen MR,
Sanusi O,
Sargi ZB,
Schafhausen P,
Schlosser RJ,
Sedaghat AR,
Senior BA,
Shrivastava R,
Sindwani R,
Smith TL,
Smith KA,
Snyderman CH,
Solares CA,
Sreenath SB,
Stamm A,
Stölzel K,
Sumer B,
Surda P,
Tajudeen BA,
Thompson LDR,
Thorp BD,
Tong CCL,
Tsang RK,
Turner JH,
Turri-Zanoni M,
Udager AM,
van Zele T,
VanKoevering K,
Welch KC,
Wise SK,
Witterick IJ,
Won TB,
Wong SN,
Woodworth BA,
Wormald PJ,
Yao WC,
Yeh CF,
Zhou B,
Palmer JN</span><br />
<span class="medgenPMjournal">Int Forum Allergy Rhinol</span>
2024 Feb;14(2):149-608.
Epub 2024 Jan 2
doi: 10.1002/alr.23262.
<span class="bold">PMID: </span><a href="/pubmed/37658764" target="_blank">37658764</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35105976">HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Lechner M,
Liu J,
Masterson L,
Fenton TR</span><br />
<span class="medgenPMjournal">Nat Rev Clin Oncol</span>
2022 May;19(5):306-327.
Epub 2022 Feb 1
doi: 10.1038/s41571-022-00603-7.
<span class="bold">PMID: </span><a href="/pubmed/35105976" target="_blank">35105976</a><a href="/pmc/articles/PMC8805140" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29180076">Delineation of the primary tumour Clinical Target Volumes (CTV-P) in laryngeal, hypopharyngeal, oropharyngeal and oral cavity squamous cell carcinoma: AIRO, CACA, DAHANCA, EORTC, GEORCC, GORTEC, HKNPCSG, HNCIG, IAG-KHT, LPRHHT, NCIC CTG, NCRI, NRG Oncology, PHNS, SBRT, SOMERA, SRO, SSHNO, TROG consensus guidelines.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Grégoire V,
Evans M,
Le QT,
Bourhis J,
Budach V,
Chen A,
Eisbruch A,
Feng M,
Giralt J,
Gupta T,
Hamoir M,
Helito JK,
Hu C,
Hunter K,
Johansen J,
Kaanders J,
Laskar SG,
Lee A,
Maingon P,
Mäkitie A,
Micciche' F,
Nicolai P,
O'Sullivan B,
Poitevin A,
Porceddu S,
Składowski K,
Tribius S,
Waldron J,
Wee J,
Yao M,
Yom SS,
Zimmermann F,
Grau C</span><br />
<span class="medgenPMjournal">Radiother Oncol</span>
2018 Jan;126(1):3-24.
Epub 2017 Nov 24
doi: 10.1016/j.radonc.2017.10.016.
<span class="bold">PMID: </span><a href="/pubmed/29180076" target="_blank">29180076</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22squamous%20cell%20carcinoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (4987)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/36252129">Squamous cell carcinoma of the tongue: subtypes and morphological features affecting prognosis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Matsuo K,
Akiba J,
Kusukawa J,
Yano H</span><br />
<span class="medgenPMjournal">Am J Physiol Cell Physiol</span>
2022 Dec 1;323(6):C1611-C1623.
Epub 2022 Oct 17
doi: 10.1152/ajpcell.00098.2022.
<span class="bold">PMID: </span><a href="/pubmed/36252129" target="_blank">36252129</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36153105">Squamous Cell Carcinoma of the Esophagus.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Codipilly DC,
Wang KK</span><br />
<span class="medgenPMjournal">Gastroenterol Clin North Am</span>
2022 Sep;51(3):457-484.
Epub 2022 Aug 29
doi: 10.1016/j.gtc.2022.06.005.
<span class="bold">PMID: </span><a href="/pubmed/36153105" target="_blank">36153105</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34329869">Overview of oral cavity squamous cell carcinoma: Risk factors, mechanisms, and diagnostics.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Chamoli A,
Gosavi AS,
Shirwadkar UP,
Wangdale KV,
Behera SK,
Kurrey NK,
Kalia K,
Mandoli A</span><br />
<span class="medgenPMjournal">Oral Oncol</span>
2021 Oct;121:105451.
Epub 2021 Jul 28
doi: 10.1016/j.oraloncology.2021.105451.
<span class="bold">PMID: </span><a href="/pubmed/34329869" target="_blank">34329869</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34274176">Lip and Oral Cavity Squamous Cell Carcinoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Howard A,
Agrawal N,
Gooi Z</span><br />
<span class="medgenPMjournal">Hematol Oncol Clin North Am</span>
2021 Oct;35(5):895-911.
Epub 2021 Jul 14
doi: 10.1016/j.hoc.2021.05.003.
<span class="bold">PMID: </span><a href="/pubmed/34274176" target="_blank">34274176</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30497667">Cutaneous Squamous Cell Carcinoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Waldman A,
Schmults C</span><br />
<span class="medgenPMjournal">Hematol Oncol Clin North Am</span>
2019 Feb;33(1):1-12.
doi: 10.1016/j.hoc.2018.08.001.
<span class="bold">PMID: </span><a href="/pubmed/30497667" target="_blank">30497667</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Squamous%20cell%20carcinoma%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (61252)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/37820338">Squamous Cell Carcinoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Heath CR,
Usatine RP</span><br />
<span class="medgenPMjournal">Cutis</span>
2023 Aug;112(2):97-98.
doi: 10.12788/cutis.0820.
<span class="bold">PMID: </span><a href="/pubmed/37820338" target="_blank">37820338</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37549403">Squamous cell carcinoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Heath CR,
Usatine RP</span><br />
<span class="medgenPMjournal">J Fam Pract</span>
2023 Jul;72(6):E13-E15.
doi: 10.12788/jfp.0644.
<span class="bold">PMID: </span><a href="/pubmed/37549403" target="_blank">37549403</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34329869">Overview of oral cavity squamous cell carcinoma: Risk factors, mechanisms, and diagnostics.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Chamoli A,
Gosavi AS,
Shirwadkar UP,
Wangdale KV,
Behera SK,
Kurrey NK,
Kalia K,
Mandoli A</span><br />
<span class="medgenPMjournal">Oral Oncol</span>
2021 Oct;121:105451.
Epub 2021 Jul 28
doi: 10.1016/j.oraloncology.2021.105451.
<span class="bold">PMID: </span><a href="/pubmed/34329869" target="_blank">34329869</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32399208">Oral squamous cell carcinoma: metastasis, potentially associated malignant disorders, etiology and recent advancements in diagnosis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Bugshan A,
Farooq I</span><br />
<span class="medgenPMjournal">F1000Res</span>
2020;9:229.
Epub 2020 Apr 2
doi: 10.12688/f1000research.22941.1.
<span class="bold">PMID: </span><a href="/pubmed/32399208" target="_blank">32399208</a><a href="/pmc/articles/PMC7194458" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30497667">Cutaneous Squamous Cell Carcinoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Waldman A,
Schmults C</span><br />
<span class="medgenPMjournal">Hematol Oncol Clin North Am</span>
2019 Feb;33(1):1-12.
doi: 10.1016/j.hoc.2018.08.001.
<span class="bold">PMID: </span><a href="/pubmed/30497667" target="_blank">30497667</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Squamous%20cell%20carcinoma%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (48017)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/38579517">Essential data variables for a minimum dataset for head and neck cancer trials and clinical research: HNCIG consensus recommendations and database.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Baliga S,
Abou-Foul AK,
Parente P,
Szturz P,
Thariat J,
Shreenivas A,
Nankivell P,
Bertolini F,
Biau J,
Blakaj D,
Brennan S,
Brunet A,
De Oliveira TB,
Burtness B,
Maseda AC,
Chow VL,
Chua ML,
de Ridder M,
Garikipati S,
Hanai N,
Ho FCH,
Huang SH,
Kiyota N,
Klinghammer K,
Kowalski LP,
Kwong DL,
McDowell LJ,
Merlano MC,
Nair S,
Economopoulou P,
Overgaard J,
Psyrri A,
Tribius S,
Waldron J,
Yom SS,
Mehanna H</span><br />
<span class="medgenPMjournal">Eur J Cancer</span>
2024 May;203:114038.
Epub 2024 Mar 30
doi: 10.1016/j.ejca.2024.114038.
<span class="bold">PMID: </span><a href="/pubmed/38579517" target="_blank">38579517</a></div>
<div class="nl"><a target="_blank" href="/pubmed/38498070">Systematic review of randomized controlled trials of topicals for actinic keratosis field therapy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Patel P,
Wang J,
Bitterman D,
Mineroff J,
Austin E,
Jagdeo J</span><br />
<span class="medgenPMjournal">Arch Dermatol Res</span>
2024 Mar 18;316(4):108.
doi: 10.1007/s00403-024-02839-y.
<span class="bold">PMID: </span><a href="/pubmed/38498070" target="_blank">38498070</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35717050">ECOG-ACRIN Guideline for Contouring and Treatment of Early Stage Anal Cancer Using IMRT/IGRT.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Damico N,
Meyer J,
Das P,
Murphy J,
Miller E,
Koontz B,
Hall W,
McBride M,
Pereira G,
Catalano P,
Chakravarthy AB,
O'Dwyer PJ,
Dorth J</span><br />
<span class="medgenPMjournal">Pract Radiat Oncol</span>
2022 Jul-Aug;12(4):335-347.
doi: 10.1016/j.prro.2022.01.015.
<span class="bold">PMID: </span><a href="/pubmed/35717050" target="_blank">35717050</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25920379">Role of chemotherapy in treatment of squamous cell carcinoma of the penis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Pagliaro LC</span><br />
<span class="medgenPMjournal">Curr Probl Cancer</span>
2015 May-Jun;39(3):166-72.
Epub 2015 Mar 31
doi: 10.1016/j.currproblcancer.2015.03.008.
<span class="bold">PMID: </span><a href="/pubmed/25920379" target="_blank">25920379</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23755889">Larynx preservation: what is the best non-surgical strategy?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Lagha A,
Chraiet N,
Labidi S,
Rifi H,
Ayadi M,
Krimi S,
Allani B,
Raies H,
Touati S,
Boussen H,
Kochbati L,
Mezlini A</span><br />
<span class="medgenPMjournal">Crit Rev Oncol Hematol</span>
2013 Nov;88(2):447-58.
Epub 2013 Jun 5
doi: 10.1016/j.critrevonc.2013.05.005.
<span class="bold">PMID: </span><a href="/pubmed/23755889" target="_blank">23755889</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Squamous%20cell%20carcinoma%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (34769)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/37030943">Management of Subglottic Cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Mann H,
Seligman K,
Colwell N,
Burr A,
Glazer TA</span><br />
<span class="medgenPMjournal">Otolaryngol Clin North Am</span>
2023 Apr;56(2):305-312.
doi: 10.1016/j.otc.2022.11.001.
<span class="bold">PMID: </span><a href="/pubmed/37030943" target="_blank">37030943</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28444227">Incidence and prognosis of patients with brain metastases at diagnosis of systemic malignancy: a population-based study.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Cagney DN,
Martin AM,
Catalano PJ,
Redig AJ,
Lin NU,
Lee EQ,
Wen PY,
Dunn IF,
Bi WL,
Weiss SE,
Haas-Kogan DA,
Alexander BM,
Aizer AA</span><br />
<span class="medgenPMjournal">Neuro Oncol</span>
2017 Oct 19;19(11):1511-1521.
doi: 10.1093/neuonc/nox077.
<span class="bold">PMID: </span><a href="/pubmed/28444227" target="_blank">28444227</a><a href="/pmc/articles/PMC5737512" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27898173">An update on larynx cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Steuer CE,
El-Deiry M,
Parks JR,
Higgins KA,
Saba NF</span><br />
<span class="medgenPMjournal">CA Cancer J Clin</span>
2017 Jan;67(1):31-50.
Epub 2016 Nov 29
doi: 10.3322/caac.21386.
<span class="bold">PMID: </span><a href="/pubmed/27898173" target="_blank">27898173</a></div>
<div class="nl"><a target="_blank" href="/pubmed/21135266">Reduced melanoma after regular sunscreen use: randomized trial follow-up.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Green AC,
Williams GM,
Logan V,
Strutton GM</span><br />
<span class="medgenPMjournal">J Clin Oncol</span>
2011 Jan 20;29(3):257-63.
Epub 2010 Dec 6
doi: 10.1200/JCO.2010.28.7078.
<span class="bold">PMID: </span><a href="/pubmed/21135266" target="_blank">21135266</a></div>
<div class="nl"><a target="_blank" href="/pubmed/17362462">Periocular squamous cell carcinoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Limawararut V,
Leibovitch I,
Sullivan T,
Selva D</span><br />
<span class="medgenPMjournal">Clin Exp Ophthalmol</span>
2007 Mar;35(2):174-85.
doi: 10.1111/j.1442-9071.2006.01411.x.
<span class="bold">PMID: </span><a href="/pubmed/17362462" target="_blank">17362462</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Squamous%20cell%20carcinoma%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (57485)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/39162820">Actinic keratosis metrics.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Burstein SE,
Maibach H</span><br />
<span class="medgenPMjournal">Arch Dermatol Res</span>
2024 Aug 20;316(8):543.
doi: 10.1007/s00403-024-03305-5.
<span class="bold">PMID: </span><a href="/pubmed/39162820" target="_blank">39162820</a><a href="/pmc/articles/PMC11335770" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34920027">Grading of differentiation in cutaneous squamous cell carcinoma: Evaluation of interrater and intrarater reliability.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Nash J,
Shahwan KT,
Chung C,
Abidi N,
Gokun Y,
Pan X,
Carr DR</span><br />
<span class="medgenPMjournal">J Am Acad Dermatol</span>
2022 Oct;87(4):895-897.
Epub 2021 Dec 15
doi: 10.1016/j.jaad.2021.12.015.
<span class="bold">PMID: </span><a href="/pubmed/34920027" target="_blank">34920027</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31319692">The role of MRI-derived depth of invasion in staging oral tongue squamous cell carcinoma: inter-reader and radiological-pathological agreement.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Vidiri A,
Panfili M,
Boellis A,
Cristalli G,
Gangemi E,
Pellini R,
Marzi S,
Covello R</span><br />
<span class="medgenPMjournal">Acta Radiol</span>
2020 Mar;61(3):344-352.
Epub 2019 Jul 18
doi: 10.1177/0284185119862946.
<span class="bold">PMID: </span><a href="/pubmed/31319692" target="_blank">31319692</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28672047">SLNB in cutaneous SCC: A review of the current state of literature and the direction for the future.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ahadiat O,
Higgins S,
Sutton A,
Ly A,
Wysong A</span><br />
<span class="medgenPMjournal">J Surg Oncol</span>
2017 Sep;116(3):344-350.
Epub 2017 Jul 3
doi: 10.1002/jso.24675.
<span class="bold">PMID: </span><a href="/pubmed/28672047" target="_blank">28672047</a></div>
<div class="nl"><a target="_blank" href="/pubmed/22815411">Interobserver variation in parotid gland delineation: a study of its impact on intensity-modulated radiotherapy solutions with a systematic review of the literature.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Loo SW,
Martin WM,
Smith P,
Cherian S,
Roques TW</span><br />
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2012 Aug;85(1016):1070-7.
doi: 10.1259/bjr/32038456.
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2024 Mar 18;316(4):108.
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<div class="portlet_content ln"><span class="medgenPMauthor">Crossley JR,
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2023 Jan;45(1):275-282.
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<div class="nl"><a target="_blank" href="/pubmed/35907576">Side effects of gel nail polish: A systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Litaiem N,
Baklouti M,
Zeglaoui F</span><br />
<span class="medgenPMjournal">Clin Dermatol</span>
2022 Nov-Dec;40(6):706-715.
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doi: 10.1016/j.clindermatol.2022.07.008.
<span class="bold">PMID: </span><a href="/pubmed/35907576" target="_blank">35907576</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33339760">Human papillomavirus infection and oral squamous cell carcinoma - a systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Melo BAC,
Vilar LG,
Oliveira NR,
Lima PO,
Pinheiro MB,
Domingueti CP,
Pereira MC</span><br />
<span class="medgenPMjournal">Braz J Otorhinolaryngol</span>
2021 May-Jun;87(3):346-352.
Epub 2020 Nov 29
doi: 10.1016/j.bjorl.2020.10.017.
<span class="bold">PMID: </span><a href="/pubmed/33339760" target="_blank">33339760</a><a href="/pmc/articles/PMC9422740" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27898189">Salivary biomarkers as tools for oral squamous cell carcinoma diagnosis: A systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Stuani VT,
Rubira CM,
Sant'Ana AC,
Santos PS</span><br />
<span class="medgenPMjournal">Head Neck</span>
2017 Apr;39(4):797-811.
Epub 2016 Nov 29
doi: 10.1002/hed.24650.
<span class="bold">PMID: </span><a href="/pubmed/27898189" target="_blank">27898189</a></div>
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<li><a href="/gtr/tests?term=C0007137%5bDISCUI%5d&amp;filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (12)</a></li>
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