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<meta name="keywords" content="C1336708, bcl10, embryonal cell carcinoma, endodermal sinus tumor, endodermal sinus tumour, fgfr3, germ cell neoplasm of testis, germ cell neoplasm of the testis, germ cell tumor of testis, germ cell tumor of the testis, germ cell tumor, somatic, germ cell tumors, somatic, germ cell tumour of testis, germ cell tumour of the testis, kit, male germ cell tumor, male germ cell tumor, somatic, male germ cell tumour, mgct, neoplastic process, nonseminomatous germ cell tumors, nonseminomatous germ cell tumours, seminoma, spermatocytic seminoma, spermatocytic seminoma, somatic, stk11, teratoma, testicular, testicular germ cell cancer, testicular germ cell neoplasm, testicular germ cell neoplasms, testicular germ cell tumor, testicular tumor, somatic, testis germ cell tumor, testis germ cell tumour, tgct, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Testicular germ cell tumors (TGCTs) affect 1 in 500 men and are the most common cancer in males aged 15 to 40 in western European populations. The incidence of TGCT rose dramatically during the 20th century. Known risk factors for TGCT include a history of undescended testis (UDT), testicular dysgenesis, infertility, previously diagnosed TGCT, and a family history of the disease. Brothers of men with TGCT have an 8- to 10-fold risk of developing TGCT, whereas the relative risk to fathers and sons is 4-fold. This familial relative risk is much higher than that for most other types of cancer (summary by Rapley et al., 2000). Genetic Heterogeneity of Testicular Germ Cell Tumors A locus for testicular germ cell tumors (TGCT1; 300228) has been identified on chromosome Xq27." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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||
UID=277809
|
||
ConceptID=C1336708
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Germ cell tumor of testis<span class="h1sub">(TGCT)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>277809</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1336708</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>GERM CELL TUMOR, SOMATIC; Testicular germ cell tumor; TGCT</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Germ cell tumor of testis (713577007)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td><a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#target-gene-loc">Genes (locations):<img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a><div class="display-none" id="target-gene-loc">
|
||
Gene(s) directly associated with<br />
|
||
this condition or phenotype.</div></td>
|
||
<td><a target="_blank" title="BCL10 - ID: 8915 - NCBI Gene" href="/gene/8915" class="medgenPMinfo">BCL10</a> (1p22.3); <a target="_blank" title="FGFR3 - ID: 2261 - NCBI Gene" href="/gene/2261" class="medgenPMinfo">FGFR3</a> (4p16.3); <a target="_blank" title="KIT - ID: 3815 - NCBI Gene" href="/gene/3815" class="medgenPMinfo">KIT</a> (4q12); <a target="_blank" title="STK11 - ID: 6794 - NCBI Gene" href="/gene/6794" class="medgenPMinfo">STK11</a> (19p13.3)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0010108" target="_blank">MONDO:0010108</a></td></tr>
|
||
<tr><td>OMIM<span class="superscript">®</span>:</td>
|
||
<td><a href="https://omim.org/entry/273300" target="_blank">273300</a></td></tr>
|
||
<tr><td>Orphanet:</td>
|
||
<td><a target="_blank" title="Orphanet: The portal for rare diseases and orphan drugs" href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=363504">ORPHA363504</a></td></tr></tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
|
||
<div class="portlet mgSection" id="ID_100">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Testicular germ cell tumors (TGCTs) affect 1 in 500 men and are the most common cancer in males aged 15 to 40 in western European populations. The incidence of TGCT rose dramatically during the 20th century. Known risk factors for TGCT include a history of undescended testis (UDT), testicular dysgenesis, infertility, previously diagnosed TGCT, and a family history of the disease. Brothers of men with TGCT have an 8- to 10-fold risk of developing TGCT, whereas the relative risk to fathers and sons is 4-fold. This familial relative risk is much higher than that for most other types of cancer (summary by Rapley et al., 2000). Genetic Heterogeneity of Testicular Germ Cell Tumors A locus for testicular germ cell tumors (TGCT1; 300228) has been identified on chromosome Xq27. [from <a title="Online Mendelian Inheritance in Man" href="http://www.omim.org" class="defSource" target="_blank">OMIM</a>]</div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_102">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_features">Clinical features</h1><a sid="102" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat"><strong>From HPO</strong><br />
|
||
<div class="divPopper rprt" id="clin_45034"><div><strong>Embryonal neoplasm</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>45034</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0027654</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A usually malignant neoplasm composed of primitive (immature) tissues that resemble fetal tissues. Medulloblastoma, ependymoblastoma, pineoblastoma, and Wilms tumor are representative embryonal neoplasms.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/45034">Feature record</a> | <a href="/medgen?term=%22Embryonal%20neoplasm%22%5BClinical%20Features%5D%20OR%2045034%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_21097"><div><strong>Teratoma</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>21097</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0039538</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The presence of a teratoma.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/21097">Feature record</a> | <a href="/medgen?term=%22Teratoma%22%5BClinical%20Features%5D%20OR%2021097%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_2150"><div><strong>Azoospermia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>2150</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0004509</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Absence of any measurable level of sperm,whereby spermatozoa cannot be observed even after centrifugation of the semen pellet.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/2150">Feature record</a> | <a href="/medgen?term=%22Azoospermia%22%5BClinical%20Features%5D%20OR%202150%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_65916"><div><strong>Elevated circulating alpha-fetoprotein concentration</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>65916</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0235971</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Concentration of alpha-fetoprotein in the blood circulation above the upper limit of normal.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/65916">Feature record</a> | <a href="/medgen?term=%22Elevated%20circulating%20alpha-fetoprotein%20concentration%22%5BClinical%20Features%5D%20OR%2065916%5Buid%5D">Search on this feature</a></div></div>
|
||
<div class="divPopper rprt" id="clin_40278"><div><strong>Choriocarcinoma</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>40278</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0008497</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A malignant, trophoblastic and aggressive cancer, usually of the placenta. It is characterized by early hematogenous spread to the lungs and belongs to the far end of the spectrum of gestational trophoblastic disease (GTD), a subset of germ cell tumors.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/40278">Feature record</a> | <a href="/medgen?term=%22Choriocarcinoma%22%5BClinical%20Features%5D%20OR%2040278%5Buid%5D">Search on this feature</a></div></div><div class="TreeLite" data-jigconfig="closed: 1"><div class="concept-def"><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().openAll(); return false;">Show all</a><a class="small" href="#" onclick="jQuery(".TreeLite","#ID_102").TreeLite().closeAll(); return false;">Hide all</a></div><ul><li><span class="TLline">Abnormality of metabolism/homeostasis</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_65916" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Elevated circulating alpha-fetoprotein concentration</a></span></li></ul></li><li><span class="TLline">Abnormality of prenatal development or birth</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_40278" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Choriocarcinoma</a></span></li></ul></li><li><span class="TLline">Abnormality of the genitourinary system</span><ul><li class="TLline">
|
||
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_2150" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Azoospermia</a></span></li></ul></li><li><span class="TLline">Neoplasm</span><ul><li class="TLline">
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<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_45034" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Embryonal neoplasm</a></span></li><li class="TLline">
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<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_21097" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Teratoma</a></span></li></ul></li></ul></div></div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0042065[DISCUI]&test_type=Clinical" ref="ncbi_uid=22583">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/22583" ref="tree=GTR&ncbi_uid=22583&link_uid=22583" title="View MedGen record for 'Neoplasm of the genitourinary tract'">Neoplasm of the genitourinary tract</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0474809[DISCUI]&test_type=Clinical&redirect=true" ref="ncbi_uid=105374">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/105374" ref="tree=GTR&ncbi_uid=105374&link_uid=105374" title="View MedGen record for 'Endometrioid tumor'">Endometrioid tumor</a></span></li><li class="TLclosed"><span class="TLline"><a href="/medgen/69146" ref="tree=GTR&ncbi_uid=69146&link_uid=69146" title="View MedGen record for 'Kidney angiomyolipoma'">Kidney angiomyolipoma</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0376358[DISCUI]&test_type=Clinical" ref="ncbi_uid=138169">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=138169" target="_blank" href="/omim/176807">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=138169" ref="ncbi_uid=138169">V</a></span></span><span class="TLline"><a href="/medgen/138169" ref="tree=GTR&ncbi_uid=138169&link_uid=138169" title="View MedGen record for 'Malignant tumor of prostate'">Malignant tumor of prostate</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C2931456[DISCUI]&test_type=Clinical" ref="ncbi_uid=419810">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=419810" ref="ncbi_uid=419810">V</a></span></span><span class="TLline"><a href="/medgen/419810" ref="tree=GTR&ncbi_uid=419810&link_uid=419810" title="View MedGen record for 'Familial prostate cancer'">Familial prostate cancer</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0153594[DISCUI]&test_type=Clinical" ref="ncbi_uid=56313">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=56313" ref="ncbi_uid=56313">V</a></span></span><span class="TLline"><a href="/medgen/56313" ref="tree=GTR&ncbi_uid=56313&link_uid=56313" title="View MedGen record for 'Malignant tumor of testis'">Malignant tumor of testis</a></span><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1336708[DISCUI]&test_type=Clinical" ref="ncbi_uid=277809">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=277809" target="_blank" href="/omim/273300">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=277809" ref="ncbi_uid=277809">V</a></span></span><span class="TLline">Germ cell tumor of testis</span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=11371" target="_blank" href="/omim/273300">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/11371" ref="tree=GTR&ncbi_uid=11371&link_uid=11371" title="View MedGen record for 'Seminoma'">Seminoma</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=68669" target="_blank" href="/omim/273300">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/68669" ref="tree=GTR&ncbi_uid=68669&link_uid=68669" title="View MedGen record for 'Testicular teratoma'">Testicular teratoma</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=102281" target="_blank" href="/omim/191600">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/102281" ref="tree=GTR&ncbi_uid=102281&link_uid=102281" title="View MedGen record for 'Malignant tumor of ureter'">Malignant tumor of ureter</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0005684[DISCUI]&test_type=Clinical" ref="ncbi_uid=14150">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=14150" target="_blank" href="/omim/109800">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=14150" ref="ncbi_uid=14150">V</a></span></span><span class="TLline"><a href="/medgen/14150" ref="tree=GTR&ncbi_uid=14150&link_uid=14150" title="View MedGen record for 'Malignant tumor of urinary bladder'">Malignant tumor of urinary bladder</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0699885[DISCUI]&test_type=Clinical" ref="ncbi_uid=147071">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/147071" ref="tree=GTR&ncbi_uid=147071&link_uid=147071" title="View MedGen record for 'Urinary bladder carcinoma'">Urinary bladder carcinoma</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0015558[DISCUI]&test_type=Clinical" ref="ncbi_uid=8775">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/8775" ref="tree=GTR&ncbi_uid=8775&link_uid=8775" title="View MedGen record for 'Neoplasm of fallopian tube'">Neoplasm of fallopian tube</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0042138[DISCUI]&test_type=Clinical" ref="ncbi_uid=12030">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=12030" ref="ncbi_uid=12030">V</a></span></span><span class="TLline"><a href="/medgen/12030" ref="tree=GTR&ncbi_uid=12030&link_uid=12030" title="View MedGen record for 'Neoplasm of uterus'">Neoplasm of uterus</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0014170[DISCUI]&test_type=Clinical" ref="ncbi_uid=8619">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/8619" ref="tree=GTR&ncbi_uid=8619&link_uid=8619" title="View MedGen record for 'Endometrium neoplasm'">Endometrium neoplasm</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0007873[DISCUI]&test_type=Clinical" ref="ncbi_uid=40201">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/40201" ref="tree=GTR&ncbi_uid=40201&link_uid=40201" title="View MedGen record for 'Neoplasm of uterine cervix'">Neoplasm of uterine cervix</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/91094" ref="tree=GTR&ncbi_uid=91094&link_uid=91094" title="View MedGen record for 'Oncocytoma of kidney'">Oncocytoma of kidney</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0919267[DISCUI]&test_type=Clinical" ref="ncbi_uid=181539">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=181539" ref="ncbi_uid=181539">V</a></span></span><span class="TLline"><a href="/medgen/181539" ref="tree=GTR&ncbi_uid=181539&link_uid=181539" title="View MedGen record for 'Ovarian neoplasm'">Ovarian neoplasm</a></span><ul><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1333992[DISCUI]&test_type=Clinical" ref="ncbi_uid=272713">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=272713" ref="ncbi_uid=272713">V</a></span></span><span class="TLline"><a href="/medgen/272713" ref="tree=GTR&ncbi_uid=272713&link_uid=272713" title="View MedGen record for 'Familial ovarian carcinoma'">Familial ovarian carcinoma</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1140680[DISCUI]&test_type=Clinical" ref="ncbi_uid=216027">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=216027" target="_blank" href="/omim/167000">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=216027" ref="ncbi_uid=216027">V</a></span></span><span class="TLline"><a href="/medgen/216027" ref="tree=GTR&ncbi_uid=216027&link_uid=216027" title="View MedGen record for 'Ovarian cancer'">Ovarian cancer</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1868358[DISCUI]&test_type=Clinical&redirect=true" ref="ncbi_uid=358303">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=358303" target="_blank" href="/omim/171834">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=358303" ref="ncbi_uid=358303">V</a></span></span><span class="TLline"><a href="/medgen/358303" ref="tree=GTR&ncbi_uid=358303&link_uid=358303" title="View MedGen record for 'OVARIAN CANCER, EPITHELIAL, SOMATIC'">OVARIAN CANCER, EPITHELIAL, SOMATIC</a></span></li></ul></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1336839[DISCUI]&test_type=Clinical" ref="ncbi_uid=237026">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=237026" target="_blank" href="/omim/164860">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=237026" ref="ncbi_uid=237026">V</a></span></span><span class="TLline"><a href="/medgen/237026" ref="tree=GTR&ncbi_uid=237026&link_uid=237026" title="View MedGen record for 'Papillary renal cell carcinoma type 1'">Papillary renal cell carcinoma type 1</a></span></li><li class="TLclosed"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C1266142[DISCUI]&test_type=Clinical" ref="ncbi_uid=690113">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline"><a href="/medgen/690113" ref="tree=GTR&ncbi_uid=690113&link_uid=690113" title="View MedGen record for 'Renal hamartoma'">Renal hamartoma</a></span></li></ul></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/21047" ref="tree=MeSH" title="MedGen record for Pathological Conditions, Signs and Symptoms">Pathological Conditions, Signs and Symptoms</a></span><ul><li><span class="TLline"><a href="/medgen/18325" ref="tree=MeSH" title="MedGen record for Pathological process">Pathological process</a></span><ul><li><span class="TLline"><a href="/medgen/4347" ref="tree=MeSH" title="MedGen record for Disease">Disease</a></span><ul><li><span class="TLline"><a href="/medgen/10294" ref="tree=MeSH" title="MedGen record for Neoplasm">Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/99182" ref="tree=MeSH" title="MedGen record for Neoplasm by Morphology">Neoplasm by Morphology</a></span><ul><li><span class="TLline"><a href="/medgen/60030" ref="tree=MeSH" title="MedGen record for Germ cell tumor">Germ cell tumor</a></span><ul><li><span class="matched_ds">Germ cell tumor of testis</span><ul><li><span class="TLline"><a href="/medgen/208758" ref="tree=MeSH" title="MedGen record for Childhood testicular germ cell tumor">Childhood testicular germ cell tumor</a></span><ul><li><span class="TLline"><a href="/medgen/209318" ref="tree=MeSH" title="MedGen record for Childhood Malignant Testicular Germ Cell Tumor">Childhood Malignant Testicular Germ Cell Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/272470" ref="tree=MeSH" title="MedGen record for Childhood embryonal testis carcinoma">Childhood embryonal testis carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/272469" ref="tree=MeSH" title="MedGen record for Childhood testicular choriocarcinoma">Childhood testicular choriocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/272471" ref="tree=MeSH" title="MedGen record for Childhood testicular mixed germ cell cancer">Childhood testicular mixed germ cell cancer</a></span></li><li><span class="TLline"><a href="/medgen/272473" ref="tree=MeSH" title="MedGen record for Childhood Testicular Yolk Sac Tumor">Childhood Testicular Yolk Sac Tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/901672" ref="tree=MeSH" title="MedGen record for Childhood Testicular Non-Seminomatous Germ Cell Tumor">Childhood Testicular Non-Seminomatous Germ Cell Tumor</a></span><ul><li><span class="TLline"><a href="/medgen/234137" ref="tree=MeSH" title="MedGen record for Childhood testicular mixed embryonal carcinoma and teratoma">Childhood testicular mixed embryonal carcinoma and teratoma</a></span></li><li><span class="TLline"><a href="/medgen/234138" ref="tree=MeSH" title="MedGen record for Childhood Testicular Teratoma">Childhood Testicular Teratoma</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/858748" ref="tree=MeSH" title="MedGen record for Familial Testicular Germ Cell Tumor">Familial Testicular Germ Cell Tumor</a></span></li><li><span class="TLline"><a href="/medgen/163616" ref="tree=MeSH" title="MedGen record for Malignant testicular germ cell tumor">Malignant testicular germ cell tumor</a></span><ul><li><span class="TLline"><a href="/medgen/202116" ref="tree=MeSH" title="MedGen record for Metastatic Malignant Testicular Germ Cell Tumor">Metastatic Malignant Testicular Germ Cell Tumor</a></span></li><li><span class="TLline"><a href="/medgen/237005" ref="tree=MeSH" title="MedGen record for Mixed testicular germ cell cancer">Mixed testicular germ cell cancer</a></span><ul><li><span class="TLline"><a href="/medgen/208972" ref="tree=MeSH" title="MedGen record for Stage I Testicular Mixed Germ Cell Tumor AJCC v6 and v7">Stage I Testicular Mixed Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/163534" ref="tree=MeSH" title="MedGen record for Stage II Testicular Mixed Germ Cell Tumor AJCC v6 and v7">Stage II Testicular Mixed Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/163618" ref="tree=MeSH" title="MedGen record for Stage III Testicular Mixed Germ Cell Tumor AJCC v6 and v7">Stage III Testicular Mixed Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/277810" ref="tree=MeSH" title="MedGen record for Testicular Mixed Choriocarcinoma and Embryonal Carcinoma">Testicular Mixed Choriocarcinoma and Embryonal Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/237002" ref="tree=MeSH" title="MedGen record for Testicular Mixed Choriocarcinoma and Seminoma">Testicular Mixed Choriocarcinoma and Seminoma</a></span></li><li><span class="TLline"><a href="/medgen/277811" ref="tree=MeSH" title="MedGen record for Testicular Mixed Choriocarcinoma and Teratoma">Testicular Mixed Choriocarcinoma and Teratoma</a></span></li><li><span class="TLline"><a href="/medgen/378931" ref="tree=MeSH" title="MedGen record for Testicular Mixed Choriocarcinoma and Yolk Sac Tumor">Testicular Mixed Choriocarcinoma and Yolk Sac Tumor</a></span></li><li><span class="TLline"><a href="/medgen/237003" ref="tree=MeSH" title="MedGen record for Testicular Mixed Embryonal Carcinoma and Seminoma">Testicular Mixed Embryonal Carcinoma and Seminoma</a></span></li><li><span class="TLline"><a href="/medgen/277812" ref="tree=MeSH" title="MedGen record for Testicular Mixed Embryonal Carcinoma and Teratoma">Testicular Mixed Embryonal Carcinoma and Teratoma</a></span></li><li><span class="TLline"><a href="/medgen/234420" ref="tree=MeSH" title="MedGen record for Testicular Mixed Embryonal Carcinoma and Teratoma with Seminoma">Testicular Mixed Embryonal Carcinoma and Teratoma with Seminoma</a></span></li><li><span class="TLline"><a href="/medgen/277813" ref="tree=MeSH" title="MedGen record for Testicular Mixed Embryonal Carcinoma and Yolk Sac Tumor">Testicular Mixed Embryonal Carcinoma and Yolk Sac Tumor</a></span></li><li><span class="TLline"><a href="/medgen/277377" ref="tree=MeSH" title="MedGen record for Testicular Mixed Embryonal Carcinoma and Yolk Sac Tumor with Seminoma">Testicular Mixed Embryonal Carcinoma and Yolk Sac Tumor with Seminoma</a></span></li><li><span class="TLline"><a href="/medgen/277814" ref="tree=MeSH" title="MedGen record for Testicular Mixed Yolk Sac Tumor and Teratoma">Testicular Mixed Yolk Sac Tumor and Teratoma</a></span></li><li><span class="TLline"><a href="/medgen/277815" ref="tree=MeSH" title="MedGen record for Testicular Mixed Yolk Sac Tumor and Teratoma with Seminoma">Testicular Mixed Yolk Sac Tumor and Teratoma with Seminoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/75879" ref="tree=MeSH" title="MedGen record for Recurrent Malignant Testicular Germ Cell Tumor">Recurrent Malignant Testicular Germ Cell Tumor</a></span></li><li><span class="TLline"><a href="/medgen/83159" ref="tree=MeSH" title="MedGen record for Spermatocytic seminoma">Spermatocytic seminoma</a></span><ul><li><span class="TLline"><a href="/medgen/273635" ref="tree=MeSH" title="MedGen record for Testicular Spermatocytic Tumor with Sarcoma">Testicular Spermatocytic Tumor with Sarcoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/234940" ref="tree=MeSH" title="MedGen record for Testicular Germ Cell Neoplasia In Situ with Extratubular Extension">Testicular Germ Cell Neoplasia In Situ with Extratubular Extension</a></span></li><li><span class="TLline"><a href="/medgen/233162" ref="tree=MeSH" title="MedGen record for Testicular non-seminomatous germ cell cancer">Testicular non-seminomatous germ cell cancer</a></span><ul><li><span class="TLline"><a href="/medgen/65969" ref="tree=MeSH" title="MedGen record for Choriocarcinoma of testis">Choriocarcinoma of testis</a></span></li><li><span class="TLline"><a href="/medgen/277766" ref="tree=MeSH" title="MedGen record for Stage I Testicular Non-Seminomatous Germ Cell Tumor AJCC v6 and v7">Stage I Testicular Non-Seminomatous Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/236911" ref="tree=MeSH" title="MedGen record for Stage II Testicular Non-Seminomatous Germ Cell Tumor AJCC v6 and v7">Stage II Testicular Non-Seminomatous Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/234851" ref="tree=MeSH" title="MedGen record for Stage III Testicular Non-Seminomatous Germ Cell Tumor AJCC v6 and v7">Stage III Testicular Non-Seminomatous Germ Cell Tumor AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/66771" ref="tree=MeSH" title="MedGen record for Testicular embryonal carcinoma">Testicular embryonal carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/237006" ref="tree=MeSH" title="MedGen record for Testicular Teratoma with Somatic-Type Malignancy">Testicular Teratoma with Somatic-Type Malignancy</a></span></li><li><span class="TLline"><a href="/medgen/79028" ref="tree=MeSH" title="MedGen record for Testicular yolk sac tumor">Testicular yolk sac tumor</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1790467" ref="tree=MeSH" title="MedGen record for Testicular seminoma">Testicular seminoma</a></span><ul><li><span class="TLline"><a href="/medgen/308258" ref="tree=MeSH" title="MedGen record for Cribriform variant testicular seminoma">Cribriform variant testicular seminoma</a></span></li><li><span class="TLline"><a href="/medgen/233471" ref="tree=MeSH" title="MedGen record for Intratubular Seminoma">Intratubular Seminoma</a></span></li><li><span class="TLline"><a href="/medgen/273633" ref="tree=MeSH" title="MedGen record for Pseudoglandular variant testicular seminoma">Pseudoglandular variant testicular seminoma</a></span></li><li><span class="TLline"><a href="/medgen/741221" ref="tree=MeSH" title="MedGen record for Stage I Testicular Seminoma AJCC v6 and v7">Stage I Testicular Seminoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/277728" ref="tree=MeSH" title="MedGen record for Stage II Testicular Seminoma AJCC v6 and v7">Stage II Testicular Seminoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/236900" ref="tree=MeSH" title="MedGen record for Stage III Testicular Seminoma AJCC v6 and v7">Stage III Testicular Seminoma AJCC v6 and v7</a></span></li><li><span class="TLline"><a href="/medgen/90797" ref="tree=MeSH" title="MedGen record for Testicular Seminoma with High Mitotic Index">Testicular Seminoma with High Mitotic Index</a></span></li><li><span class="TLline"><a href="/medgen/273634" ref="tree=MeSH" title="MedGen record for Testicular Seminoma with Syncytiotrophoblastic Cells">Testicular Seminoma with Syncytiotrophoblastic Cells</a></span></li><li><span class="TLline"><a href="/medgen/364806" ref="tree=MeSH" title="MedGen record for Testicular Typical Seminoma">Testicular Typical Seminoma</a></span></li><li><span class="TLline"><a href="/medgen/308259" ref="tree=MeSH" title="MedGen record for Tubular variant testicular seminoma">Tubular variant testicular seminoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/271324" ref="tree=MeSH" title="MedGen record for Testis polyembryoma">Testis polyembryoma</a></span></li><li><span class="TLline"><a href="/medgen/235122" ref="tree=MeSH" title="MedGen record for Testis refractory cancer">Testis refractory cancer</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/698672" ref="tree=MeSH" title="MedGen record for Regressed Testicular Germ Cell Tumor">Regressed Testicular Germ Cell Tumor</a></span></li><li><span class="TLline"><a href="/medgen/890627" ref="tree=MeSH" title="MedGen record for Testicular non-seminomatous germ cell tumor">Testicular non-seminomatous germ cell tumor</a></span></li><li><span class="TLline"><a href="/medgen/308089" ref="tree=MeSH" title="MedGen record for Testicular pure germ cell tumor">Testicular pure germ cell tumor</a></span><ul><li><span class="TLline"><a href="/medgen/68669" ref="tree=MeSH" title="MedGen record for Testicular teratoma">Testicular teratoma</a></span><ul><li><span class="TLline"><a href="/medgen/232636" ref="tree=MeSH" title="MedGen record for Malignant teratoma of testis">Malignant teratoma of testis</a></span></li><li><span class="TLline"><a href="/medgen/307795" ref="tree=MeSH" title="MedGen record for Monodermal Testicular Teratoma">Monodermal Testicular Teratoma</a></span></li><li><span class="TLline"><a href="/medgen/233166" ref="tree=MeSH" title="MedGen record for Testicular Mature Teratoma">Testicular Mature Teratoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/272844" ref="tree=MeSH" title="MedGen record for Testicular trophoblastic tumor">Testicular trophoblastic tumor</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
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||
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<div class="portlet mgSection" id="ID_105">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35916666">The contemporary management of cancers of the sinonasal tract in adults.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Thawani R,
|
||
Kim MS,
|
||
Arastu A,
|
||
Feng Z,
|
||
West MT,
|
||
Taflin NF,
|
||
Thein KZ,
|
||
Li R,
|
||
Geltzeiler M,
|
||
Lee N,
|
||
Fuller CD,
|
||
Grandis JR,
|
||
Floudas CS,
|
||
Heinrich MC,
|
||
Hanna E,
|
||
Chandra RA</span><br />
|
||
<span class="medgenPMjournal">CA Cancer J Clin</span>
|
||
2023 Jan;73(1):72-112.
|
||
Epub 2022 Aug 2
|
||
doi: 10.3322/caac.21752.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35916666" target="_blank">35916666</a><a href="/pmc/articles/PMC9840681" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31805523">Testicular Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gilligan T,
|
||
Lin DW,
|
||
Aggarwal R,
|
||
Chism D,
|
||
Cost N,
|
||
Derweesh IH,
|
||
Emamekhoo H,
|
||
Feldman DR,
|
||
Geynisman DM,
|
||
Hancock SL,
|
||
LaGrange C,
|
||
Levine EG,
|
||
Longo T,
|
||
Lowrance W,
|
||
McGregor B,
|
||
Monk P,
|
||
Picus J,
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||
Pierorazio P,
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||
Rais-Bahrami S,
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||
Saylor P,
|
||
Sircar K,
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||
Smith DC,
|
||
Tzou K,
|
||
Vaena D,
|
||
Vaughn D,
|
||
Yamoah K,
|
||
Yamzon J,
|
||
Johnson-Chilla A,
|
||
Keller J,
|
||
Pluchino LA</span><br />
|
||
<span class="medgenPMjournal">J Natl Compr Canc Netw</span>
|
||
2019 Dec;17(12):1529-1554.
|
||
doi: 10.6004/jnccn.2019.0058.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31805523" target="_blank">31805523</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31277732">Current Management of Disseminated Germ Cell Tumors.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lavoie JM,
|
||
Kollmannsberger CK</span><br />
|
||
<span class="medgenPMjournal">Urol Clin North Am</span>
|
||
2019 Aug;46(3):377-388.
|
||
Epub 2019 May 21
|
||
doi: 10.1016/j.ucl.2019.04.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31277732" target="_blank">31277732</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(germ%20cell%20tumor%20of%20testis)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (358)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34606083">Robotic versus Laparoscopic Retroperitoneal Lymph node Dissection for Clinical Stage I Non-seminomatous Germ Cell Tumor of Testis: A Comparative Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Xu Y,
|
||
Li H,
|
||
Wang B,
|
||
Gu L,
|
||
Gao Y,
|
||
Fan Y,
|
||
Yao Y,
|
||
Fam X,
|
||
Ma X,
|
||
Zhang X</span><br />
|
||
<span class="medgenPMjournal">Urol J</span>
|
||
2021 Oct 4;18(6):618-622.
|
||
doi: 10.22037/uj.v18i.6629.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34606083" target="_blank">34606083</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30859760">Radiological nodule behavior: A critical parameter in the surgical management of pediatric pulmonary metastases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Divarcı E,
|
||
Arslan S,
|
||
Dökümcü Z,
|
||
Kantar M,
|
||
Demirağ B,
|
||
Öniz H,
|
||
Ertan Y,
|
||
Alper H,
|
||
Erdener A,
|
||
Özcan C</span><br />
|
||
<span class="medgenPMjournal">Turk J Pediatr</span>
|
||
2018;60(4):372-379.
|
||
doi: 10.24953/turkjped.2018.04.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30859760" target="_blank">30859760</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15073113">Gene expression profiling of early- and late-relapse nonseminomatous germ cell tumor and primitive neuroectodermal tumor of the testis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sugimura J,
|
||
Foster RS,
|
||
Cummings OW,
|
||
Kort EJ,
|
||
Takahashi M,
|
||
Lavery TT,
|
||
Furge KA,
|
||
Einhorn LH,
|
||
Teh BT</span><br />
|
||
<span class="medgenPMjournal">Clin Cancer Res</span>
|
||
2004 Apr 1;10(7):2368-78.
|
||
doi: 10.1158/1078-0432.ccr-03-0341.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15073113" target="_blank">15073113</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9615319">The stage I yolk sac tumor of testis in children younger than 2 years, chemotherapy or not?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu HC,
|
||
Liang DC,
|
||
Chen SH,
|
||
Liu FL,
|
||
Chang PY,
|
||
Sheu JC,
|
||
Wang NL</span><br />
|
||
<span class="medgenPMjournal">Pediatr Hematol Oncol</span>
|
||
1998 May-Jun;15(3):223-8.
|
||
doi: 10.3109/08880019809028788.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9615319" target="_blank">9615319</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2171316">Observation after orchiectomy in clinical stage I nonseminomatous germ cell tumor of testis. Mayo Clinic experience.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Patel SR,
|
||
Richardson RL,
|
||
Kvols L,
|
||
Zincke H</span><br />
|
||
<span class="medgenPMjournal">Am J Clin Oncol</span>
|
||
1990 Oct;13(5):379-81.
|
||
doi: 10.1097/00000421-199010000-00003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2171316" target="_blank">2171316</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Germ%20cell%20tumor%20of%20testis%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (6)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/30859760">Radiological nodule behavior: A critical parameter in the surgical management of pediatric pulmonary metastases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Divarcı E,
|
||
Arslan S,
|
||
Dökümcü Z,
|
||
Kantar M,
|
||
Demirağ B,
|
||
Öniz H,
|
||
Ertan Y,
|
||
Alper H,
|
||
Erdener A,
|
||
Özcan C</span><br />
|
||
<span class="medgenPMjournal">Turk J Pediatr</span>
|
||
2018;60(4):372-379.
|
||
doi: 10.24953/turkjped.2018.04.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30859760" target="_blank">30859760</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25204991">Clinical presentation features of testicular cancer in public hospitals in the Autonomous Community of Madrid, Spain.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Moreno A,
|
||
Domínguez A,
|
||
Alpuente C,
|
||
Hernándo A,
|
||
Torres J,
|
||
Cabrera JA</span><br />
|
||
<span class="medgenPMjournal">Actas Urol Esp</span>
|
||
2015 Jan-Feb;39(1):2-7.
|
||
Epub 2014 Sep 7
|
||
doi: 10.1016/j.acuro.2014.03.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25204991" target="_blank">25204991</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15073113">Gene expression profiling of early- and late-relapse nonseminomatous germ cell tumor and primitive neuroectodermal tumor of the testis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sugimura J,
|
||
Foster RS,
|
||
Cummings OW,
|
||
Kort EJ,
|
||
Takahashi M,
|
||
Lavery TT,
|
||
Furge KA,
|
||
Einhorn LH,
|
||
Teh BT</span><br />
|
||
<span class="medgenPMjournal">Clin Cancer Res</span>
|
||
2004 Apr 1;10(7):2368-78.
|
||
doi: 10.1158/1078-0432.ccr-03-0341.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15073113" target="_blank">15073113</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9615319">The stage I yolk sac tumor of testis in children younger than 2 years, chemotherapy or not?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu HC,
|
||
Liang DC,
|
||
Chen SH,
|
||
Liu FL,
|
||
Chang PY,
|
||
Sheu JC,
|
||
Wang NL</span><br />
|
||
<span class="medgenPMjournal">Pediatr Hematol Oncol</span>
|
||
1998 May-Jun;15(3):223-8.
|
||
doi: 10.3109/08880019809028788.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9615319" target="_blank">9615319</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2171316">Observation after orchiectomy in clinical stage I nonseminomatous germ cell tumor of testis. Mayo Clinic experience.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Patel SR,
|
||
Richardson RL,
|
||
Kvols L,
|
||
Zincke H</span><br />
|
||
<span class="medgenPMjournal">Am J Clin Oncol</span>
|
||
1990 Oct;13(5):379-81.
|
||
doi: 10.1097/00000421-199010000-00003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2171316" target="_blank">2171316</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Germ%20cell%20tumor%20of%20testis%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (8)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34606083">Robotic versus Laparoscopic Retroperitoneal Lymph node Dissection for Clinical Stage I Non-seminomatous Germ Cell Tumor of Testis: A Comparative Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Xu Y,
|
||
Li H,
|
||
Wang B,
|
||
Gu L,
|
||
Gao Y,
|
||
Fan Y,
|
||
Yao Y,
|
||
Fam X,
|
||
Ma X,
|
||
Zhang X</span><br />
|
||
<span class="medgenPMjournal">Urol J</span>
|
||
2021 Oct 4;18(6):618-622.
|
||
doi: 10.22037/uj.v18i.6629.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34606083" target="_blank">34606083</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15302506">Solitary skull recurrence from stage I seminomatous germ cell tumor of testis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Spermon JR,
|
||
Oyen WJ,
|
||
Strijk SP,
|
||
Hulsbergen-van de Kaa CA,
|
||
Witjes JA</span><br />
|
||
<span class="medgenPMjournal">Urology</span>
|
||
2004 Aug;64(2):377-9.
|
||
doi: 10.1016/j.urology.2004.03.048.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15302506" target="_blank">15302506</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9615319">The stage I yolk sac tumor of testis in children younger than 2 years, chemotherapy or not?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu HC,
|
||
Liang DC,
|
||
Chen SH,
|
||
Liu FL,
|
||
Chang PY,
|
||
Sheu JC,
|
||
Wang NL</span><br />
|
||
<span class="medgenPMjournal">Pediatr Hematol Oncol</span>
|
||
1998 May-Jun;15(3):223-8.
|
||
doi: 10.3109/08880019809028788.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9615319" target="_blank">9615319</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/3036401">Initial assessment of tumor-associated antigen CA-125 in patients with ovarian, cervical, and testicular tumors.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Buamah PK,
|
||
Cornell C,
|
||
Skillen AW,
|
||
Cantwell BM,
|
||
Harris AL</span><br />
|
||
<span class="medgenPMjournal">Clin Chem</span>
|
||
1987 Jul;33(7):1124-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/3036401" target="_blank">3036401</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/3008399">Indolent nonseminomatous germ cell tumor of testis. Prolonged survival of patient with persistent metastatic disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Baker TM,
|
||
Chan AH,
|
||
Stutz FH</span><br />
|
||
<span class="medgenPMjournal">Urology</span>
|
||
1986 Apr;27(4):349-52.
|
||
doi: 10.1016/0090-4295(86)90312-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/3008399" target="_blank">3008399</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Germ%20cell%20tumor%20of%20testis%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/30859760">Radiological nodule behavior: A critical parameter in the surgical management of pediatric pulmonary metastases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Divarcı E,
|
||
Arslan S,
|
||
Dökümcü Z,
|
||
Kantar M,
|
||
Demirağ B,
|
||
Öniz H,
|
||
Ertan Y,
|
||
Alper H,
|
||
Erdener A,
|
||
Özcan C</span><br />
|
||
<span class="medgenPMjournal">Turk J Pediatr</span>
|
||
2018;60(4):372-379.
|
||
doi: 10.24953/turkjped.2018.04.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30859760" target="_blank">30859760</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15073113">Gene expression profiling of early- and late-relapse nonseminomatous germ cell tumor and primitive neuroectodermal tumor of the testis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sugimura J,
|
||
Foster RS,
|
||
Cummings OW,
|
||
Kort EJ,
|
||
Takahashi M,
|
||
Lavery TT,
|
||
Furge KA,
|
||
Einhorn LH,
|
||
Teh BT</span><br />
|
||
<span class="medgenPMjournal">Clin Cancer Res</span>
|
||
2004 Apr 1;10(7):2368-78.
|
||
doi: 10.1158/1078-0432.ccr-03-0341.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15073113" target="_blank">15073113</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9615319">The stage I yolk sac tumor of testis in children younger than 2 years, chemotherapy or not?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu HC,
|
||
Liang DC,
|
||
Chen SH,
|
||
Liu FL,
|
||
Chang PY,
|
||
Sheu JC,
|
||
Wang NL</span><br />
|
||
<span class="medgenPMjournal">Pediatr Hematol Oncol</span>
|
||
1998 May-Jun;15(3):223-8.
|
||
doi: 10.3109/08880019809028788.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9615319" target="_blank">9615319</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2171316">Observation after orchiectomy in clinical stage I nonseminomatous germ cell tumor of testis. Mayo Clinic experience.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Patel SR,
|
||
Richardson RL,
|
||
Kvols L,
|
||
Zincke H</span><br />
|
||
<span class="medgenPMjournal">Am J Clin Oncol</span>
|
||
1990 Oct;13(5):379-81.
|
||
doi: 10.1097/00000421-199010000-00003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2171316" target="_blank">2171316</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/3008399">Indolent nonseminomatous germ cell tumor of testis. Prolonged survival of patient with persistent metastatic disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Baker TM,
|
||
Chan AH,
|
||
Stutz FH</span><br />
|
||
<span class="medgenPMjournal">Urology</span>
|
||
1986 Apr;27(4):349-52.
|
||
doi: 10.1016/0090-4295(86)90312-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/3008399" target="_blank">3008399</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Germ%20cell%20tumor%20of%20testis%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/30859760">Radiological nodule behavior: A critical parameter in the surgical management of pediatric pulmonary metastases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Divarcı E,
|
||
Arslan S,
|
||
Dökümcü Z,
|
||
Kantar M,
|
||
Demirağ B,
|
||
Öniz H,
|
||
Ertan Y,
|
||
Alper H,
|
||
Erdener A,
|
||
Özcan C</span><br />
|
||
<span class="medgenPMjournal">Turk J Pediatr</span>
|
||
2018;60(4):372-379.
|
||
doi: 10.24953/turkjped.2018.04.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30859760" target="_blank">30859760</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2171316">Observation after orchiectomy in clinical stage I nonseminomatous germ cell tumor of testis. Mayo Clinic experience.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Patel SR,
|
||
Richardson RL,
|
||
Kvols L,
|
||
Zincke H</span><br />
|
||
<span class="medgenPMjournal">Am J Clin Oncol</span>
|
||
1990 Oct;13(5):379-81.
|
||
doi: 10.1097/00000421-199010000-00003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2171316" target="_blank">2171316</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Germ%20cell%20tumor%20of%20testis%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div>
|
||
|
||
<!-- MedGen supplemental column starts here -->
|
||
<div class="rightCol mgCol">
|
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<div class="portlet mgSection" id="ID_113">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul id="my-toc"></ul></div>
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<div class="portlet mgSection" id="ID_106">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C1336708%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (23)</a></li>
|
||
<li><a href="/gtr/tests?term=C1336708%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (17)</a></li>
|
||
<li><a href="/gtr/tests?term=C1336708%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (3)</a></li>
|
||
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C1336708%5bDISCUI%5d" target="_blank">See all (27)</a></total></li>
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</ul></div>
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</div>
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<div class="portlet mgSection" id="ID_119">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="https://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=273300" target="_blank">OMIM</a></li><li><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Expert=363504" target="_blank">Orphanet</a></li><li><a href="https://clinicaltrials.gov/search?cond=Germ%20cell%20tumor%20of%20testis" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(germ%20cell%20tumor%20of%20testis)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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<div class="portlet mgSection" id="ID_115">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Molecular_resources">Molecular resources</h1><a sid="115" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="http://www.omim.org/search?index=entry&start=1&limit=10&sort=score%20desc&field=number&search=134934%20164920%20602216%20603517" target="_blank">OMIM</a></li><li><a href="/clinvar/?term=2261[geneid]" target="_blank">View FGFR3 variations in ClinVar</a></li><li><a href="/clinvar/?term=3815[geneid]" target="_blank">View KIT variations in ClinVar</a></li><li><a href="/clinvar/?term=6794[geneid]" target="_blank">View STK11 variations in ClinVar</a></li><li><a href="/clinvar/?term=8915[geneid]" target="_blank">View BCL10 variations in ClinVar</a></li><li><a href="/nuccore/170014706,170014710,238018114,255522834" target="_blank">RefSeqGene</a></li><li><a href="https://catalog.coriell.org/Search?q=273300" target="_blank">Coriell Institute for Medical Research</a></li></ul></div>
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</div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Consumer_resources">Consumer resources</h1><a sid="116" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="https://www.malacards.org/card/testicular_germ_cell_tumor" target="_blank">MalaCards</a></li><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Germ%20cell%20tumor%20of%20testis" target="_blank">MedlinePlus</a></li><li><a href="https://rarediseases.info.nih.gov/diseases/13047/disease" target="_blank">NCATS Office of Rare Diseases Research (GARD)</a></li></ul></div>
|
||
</div>
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||
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<h3>Reviews</h3>
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<ul>
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<a href="/pubmed/clinical?term=Germ%20cell%20tumor%20of%20testis" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=1&linkpostotal=2" target="_blank">PubMed Clinical Queries</a>
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|
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<a href="/pubmed?term=Germ%20cell%20tumor%20of%20testis%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=2&linkpostotal=2" target="_blank">Reviews in PubMed</a>
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