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<meta name="keywords" content="C1277187, disease or syndrome, dysfunction, lv systolic, left cardiac ventricular systolic dysfunction, left ventricular systolic dysfunction, lv systolic dysfunction, lv systolic dysfunctions, systolic dysfunction, lv, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Abnormality of left ventricular contraction, often defined operationally as an ejection fraction of less than 40 percent." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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UID=226908
|
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ConceptID=C1277187
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Left ventricular systolic dysfunction</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>226908</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1277187</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Dysfunction, LV Systolic; Left Ventricular Systolic Dysfunction; LV Systolic Dysfunction; LV Systolic Dysfunctions; Systolic Dysfunction, LV</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Left ventricular systolic dysfunction (134401001)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0025169">HP:0025169</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Abnormality of left ventricular contraction, often defined operationally as an ejection fraction of less than 40 percent. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Left ventricular systolic dysfunction</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/232130" ref="tree=MeSH" title="MedGen record for Disorder by Site">Disorder by Site</a></span><ul><li><span class="TLline"><a href="/medgen/2848" ref="tree=MeSH" title="MedGen record for Disorder of cardiovascular system">Disorder of cardiovascular system</a></span><ul><li><span class="TLline"><a href="/medgen/116727" ref="tree=MeSH" title="MedGen record for Abnormality of the cardiovascular system">Abnormality of the cardiovascular system</a></span><ul><li><span class="TLline"><a href="/medgen/869166" ref="tree=MeSH" title="MedGen record for Abnormal cardiovascular system physiology">Abnormal cardiovascular system physiology</a></span><ul><li><span class="TLline"><a href="/medgen/906971" ref="tree=MeSH" title="MedGen record for Abnormal cardiac ventricular function">Abnormal cardiac ventricular function</a></span><ul><li><span class="TLline"><a href="/medgen/69237" ref="tree=MeSH" title="MedGen record for Abnormal left ventricular function">Abnormal left ventricular function</a></span><ul><li><span class="matched_ds">Left ventricular systolic dysfunction</span><ul><li><span class="TLline"><a href="/medgen/1815108" ref="tree=MeSH" title="MedGen record for Abnormal left ventricular endsystolic diameter">Abnormal left ventricular endsystolic diameter</a></span><ul><li><span class="TLline"><a href="/medgen/1815109" ref="tree=MeSH" title="MedGen record for Reduced left ventricular endsystolic diameter">Reduced left ventricular endsystolic diameter</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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||
</div>
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<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_416441"><div><strong>Dilated cardiomyopathy 1DD</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>416441</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2750995</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">An autosomal dominant subtype of dilated cardiomyopathy caused by mutation(s) in the RBM20 gene, encoding RNA-binding protein 20.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/416441">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_461766"><div><strong>Muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>461766</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3150416</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">MDDGB2 is an autosomal recessive congenital muscular dystrophy associated with impaired intellectual development and mild structural brain abnormalities (Yanagisawa et al., 2007). It is part of a group of similar disorders, collectively known as 'dystroglycanopathies,' resulting from defective glycosylation of alpha-dystroglycan (DAG1; 128239) (Godfrey et al., 2007). For a discussion of genetic heterogeneity of congenital muscular dystrophy-dystroglycanopathy type B, see MDDGB1 (613155).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/461766">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_815618"><div><strong>Left ventricular noncompaction 8</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>815618</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3809288</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Some individuals with left ventricular noncompaction experience no symptoms at all; others have heart problems that can include sudden cardiac death. Additional signs and symptoms include abnormal blood clots, irregular heart rhythm (arrhythmia), a sensation of fluttering or pounding in the chest (palpitations), extreme fatigue during exercise (exercise intolerance), shortness of breath (dyspnea), fainting (syncope), swelling of the legs (lymphedema), and trouble laying down flat. Some affected individuals have features of other heart defects. Left ventricular noncompaction can be diagnosed at any age, from birth to late adulthood. Approximately two-thirds of individuals with left ventricular noncompaction develop heart failure.\n\nLeft ventricular noncompaction is a heart (cardiac) muscle disorder that occurs when the lower left chamber of the heart (left ventricle), which helps the heart pump blood, does not develop correctly. Instead of the muscle being smooth and firm, the cardiac muscle in the left ventricle is thick and appears spongy. The abnormal cardiac muscle is weak and has an impaired ability to pump blood because it either cannot completely contract or it cannot completely relax. For the heart to pump blood normally, cardiac muscle must contract and relax fully.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/815618">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1751884"><div><strong>Mitochondrial complex 2 deficiency, nuclear type 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1751884</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5436934</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Mitochondrial complex II deficiency nuclear type 3 (MC2DN3) is an autosomal recessive multisystemic metabolic disorder with a highly variable phenotype. Some patients may have an encephalomyopathic picture with episodic developmental regression, loss of motor skills, hypotonia, ataxia, dystonia, and seizures or myoclonus. Other patients present in infancy with hypertrophic cardiomyopathy, which may be fatal. Laboratory studies show increased serum lactate and mitochondrial complex II deficiency in muscle and fibroblasts (summary by Jackson et al., 2014 and Alston et al., 2015). For a discussion of genetic heterogeneity of MC2DN, see MC2DN1 (252011).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1751884">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1779589"><div><strong>Hypotaurinemic retinal degeneration and cardiomyopathy</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1779589</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5542181</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hypotaurinemic retinal degeneration and cardiomyopathy (HTRDC) is an autosomal recessive disorder characterized by low plasma taurine, childhood-onset progressive retinal degeneration, and cardiomyopathy (Ansar et al., 2020).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1779589">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1808193"><div><strong>Intellectual disability and myopathy syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1808193</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5676904</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Intellectual disability and myopathy syndrome (IDMYS) is an autosomal recessive developmental disorder characterized by global developmental delay with mildly impaired intellectual development, hypotonia, muscle weakness and fatigue, and white matter abnormalities on brain imaging. Variable additional features may include sensorineural hearing loss, dysmorphic facies, and progressive heart disease (summary by Smeland et al., 2019).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1808193">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1847702"><div><strong>Arrhythmogenic cardiomyopathy with variable ectodermal abnormalities</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1847702</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5882696</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Arrhythmogenic cardiomyopathy with variable ectodermal abnormalities (ARCME) is characterized by severe dilated cardiomyopathy resulting in death or cardiac transplantation in childhood. Ventricular tachycardia, sustained or nonsustained, has been reported. In addition, some patients exhibit ectodermal manifestations including woolly or wiry hair, dental anomalies, dry skin, and/or dystrophic nails. Cleft lip and palate and corneal abnormalities have also been observed (Robinson et al., 2020; Henry et al., 2022).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1847702">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1847702" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Arrhythmogenic cardiomyopathy with variable ectodermal abnormalities</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_416441" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Dilated cardiomyopathy 1DD</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1779589" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hypotaurinemic retinal degeneration and cardiomyopathy</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1808193" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Intellectual disability and myopathy syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_815618" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Left ventricular noncompaction 8</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1751884" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Mitochondrial complex 2 deficiency, nuclear type 3</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_461766" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Muscular dystrophy-dystroglycanopathy (congenital with intellectual disability), type B2</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33153586">Evaluation and Management of Patients With Stable Angina: Beyond the Ischemia Paradigm: JACC State-of-the-Art Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ferraro R,
|
||
Latina JM,
|
||
Alfaddagh A,
|
||
Michos ED,
|
||
Blaha MJ,
|
||
Jones SR,
|
||
Sharma G,
|
||
Trost JC,
|
||
Boden WE,
|
||
Weintraub WS,
|
||
Lima JAC,
|
||
Blumenthal RS,
|
||
Fuster V,
|
||
Arbab-Zadeh A</span><br />
|
||
<span class="medgenPMjournal">J Am Coll Cardiol</span>
|
||
2020 Nov 10;76(19):2252-2266.
|
||
doi: 10.1016/j.jacc.2020.08.078.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33153586" target="_blank">33153586</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27753502">Carbon Monoxide Poisoning: Pathogenesis, Management, and Future Directions of Therapy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rose JJ,
|
||
Wang L,
|
||
Xu Q,
|
||
McTiernan CF,
|
||
Shiva S,
|
||
Tejero J,
|
||
Gladwin MT</span><br />
|
||
<span class="medgenPMjournal">Am J Respir Crit Care Med</span>
|
||
2017 Mar 1;195(5):596-606.
|
||
doi: 10.1164/rccm.201606-1275CI.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27753502" target="_blank">27753502</a><a href="/pmc/articles/PMC5363978" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26926974">Aortic Stenosis: Diagnosis and Treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Grimard BH,
|
||
Safford RE,
|
||
Burns EL</span><br />
|
||
<span class="medgenPMjournal">Am Fam Physician</span>
|
||
2016 Mar 1;93(5):371-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26926974" target="_blank">26926974</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22left%20ventricular%20systolic%20dysfunction%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (215)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39551553">Cardiotoxicity of Anthracyclines.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Balough E,
|
||
Ariza A,
|
||
Asnani A,
|
||
Hoeger CW</span><br />
|
||
<span class="medgenPMjournal">Cardiol Clin</span>
|
||
2025 Feb;43(1):111-127.
|
||
Epub 2024 Oct 5
|
||
doi: 10.1016/j.ccl.2024.08.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39551553" target="_blank">39551553</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/39389744">Myocardial Revascularization in Heart Failure: A State-of-the-Art Review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tannu M,
|
||
Nelson AJ,
|
||
Rymer JA,
|
||
Jones WS</span><br />
|
||
<span class="medgenPMjournal">J Card Fail</span>
|
||
2024 Oct;30(10):1330-1342.
|
||
doi: 10.1016/j.cardfail.2024.08.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39389744" target="_blank">39389744</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38639702">Mapping and Ablation of Premature Ventricular Complexes: State of the Art.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Enriquez A,
|
||
Muser D,
|
||
Markman TM,
|
||
Garcia F</span><br />
|
||
<span class="medgenPMjournal">JACC Clin Electrophysiol</span>
|
||
2024 Jun;10(6):1206-1222.
|
||
Epub 2024 Apr 17
|
||
doi: 10.1016/j.jacep.2024.02.008.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38639702" target="_blank">38639702</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37321694">Pacing-Induced Cardiomyopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Khurshid S,
|
||
Frankel DS</span><br />
|
||
<span class="medgenPMjournal">Cardiol Clin</span>
|
||
2023 Aug;41(3):449-461.
|
||
doi: 10.1016/j.ccl.2023.03.010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37321694" target="_blank">37321694</a><a href="/pmc/articles/PMC11194687" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34689900">Pacing-Induced Cardiomyopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Khurshid S,
|
||
Frankel DS</span><br />
|
||
<span class="medgenPMjournal">Card Electrophysiol Clin</span>
|
||
2021 Dec;13(4):741-753.
|
||
Epub 2021 Sep 23
|
||
doi: 10.1016/j.ccep.2021.06.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34689900" target="_blank">34689900</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Left%20ventricular%20systolic%20dysfunction%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2052)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35688470">An interesting case of fever and left ventricular systolic dysfunction.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ioannou A</span><br />
|
||
<span class="medgenPMjournal">Heart</span>
|
||
2022 Jun 10;108(13):1011-1074.
|
||
doi: 10.1136/heartjnl-2022-320831.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35688470" target="_blank">35688470</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34449851">Peripartum Cardiomyopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Farrell AS,
|
||
Kuller JA,
|
||
Goldstein SA,
|
||
Dotters-Katz SK</span><br />
|
||
<span class="medgenPMjournal">Obstet Gynecol Surv</span>
|
||
2021 Aug;76(8):485-492.
|
||
doi: 10.1097/OGX.0000000000000903.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34449851" target="_blank">34449851</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30328663">Markers of left ventricular systolic dysfunction when left ventricular ejection fraction is normal.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nauta JF,
|
||
Jin X,
|
||
Hummel YM,
|
||
Voors AA</span><br />
|
||
<span class="medgenPMjournal">Eur J Heart Fail</span>
|
||
2018 Dec;20(12):1636-1638.
|
||
Epub 2018 Oct 17
|
||
doi: 10.1002/ejhf.1326.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30328663" target="_blank">30328663</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27884252">Differentiation of Constriction and Restriction: Complex Cardiovascular Hemodynamics.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Geske JB,
|
||
Anavekar NS,
|
||
Nishimura RA,
|
||
Oh JK,
|
||
Gersh BJ</span><br />
|
||
<span class="medgenPMjournal">J Am Coll Cardiol</span>
|
||
2016 Nov 29;68(21):2329-2347.
|
||
doi: 10.1016/j.jacc.2016.08.050.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27884252" target="_blank">27884252</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26926974">Aortic Stenosis: Diagnosis and Treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Grimard BH,
|
||
Safford RE,
|
||
Burns EL</span><br />
|
||
<span class="medgenPMjournal">Am Fam Physician</span>
|
||
2016 Mar 1;93(5):371-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26926974" target="_blank">26926974</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Left%20ventricular%20systolic%20dysfunction%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1369)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37321694">Pacing-Induced Cardiomyopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Khurshid S,
|
||
Frankel DS</span><br />
|
||
<span class="medgenPMjournal">Cardiol Clin</span>
|
||
2023 Aug;41(3):449-461.
|
||
doi: 10.1016/j.ccl.2023.03.010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37321694" target="_blank">37321694</a><a href="/pmc/articles/PMC11194687" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25480690">Outpatient management of chronic heart failure.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kaldara E,
|
||
Sanoudou D,
|
||
Adamopoulos S,
|
||
Nanas JN</span><br />
|
||
<span class="medgenPMjournal">Expert Opin Pharmacother</span>
|
||
2015 Jan;16(1):17-41.
|
||
Epub 2014 Dec 5
|
||
doi: 10.1517/14656566.2015.978286.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25480690" target="_blank">25480690</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23313577">Biomarkers and diagnostics in heart failure.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gaggin HK,
|
||
Januzzi JL Jr</span><br />
|
||
<span class="medgenPMjournal">Biochim Biophys Acta</span>
|
||
2013 Dec;1832(12):2442-50.
|
||
Epub 2013 Jan 9
|
||
doi: 10.1016/j.bbadis.2012.12.014.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23313577" target="_blank">23313577</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15753115">The effect of cardiac resynchronization on morbidity and mortality in heart failure.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cleland JG,
|
||
Daubert JC,
|
||
Erdmann E,
|
||
Freemantle N,
|
||
Gras D,
|
||
Kappenberger L,
|
||
Tavazzi L;
|
||
Cardiac Resynchronization-Heart Failure (CARE-HF) Study Investigators</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2005 Apr 14;352(15):1539-49.
|
||
Epub 2005 Mar 7
|
||
doi: 10.1056/NEJMoa050496.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15753115" target="_blank">15753115</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11356434">Effect of carvedilol on outcome after myocardial infarction in patients with left-ventricular dysfunction: the CAPRICORN randomised trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dargie HJ</span><br />
|
||
<span class="medgenPMjournal">Lancet</span>
|
||
2001 May 5;357(9266):1385-90.
|
||
doi: 10.1016/s0140-6736(00)04560-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11356434" target="_blank">11356434</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Left%20ventricular%20systolic%20dysfunction%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1261)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38334818">Epidemiology of heart failure in diabetes: a disease in disguise.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hoek AG,
|
||
Dal Canto E,
|
||
Wenker E,
|
||
Bindraban N,
|
||
Handoko ML,
|
||
Elders PJM,
|
||
Beulens JWJ</span><br />
|
||
<span class="medgenPMjournal">Diabetologia</span>
|
||
2024 Apr;67(4):574-601.
|
||
Epub 2024 Feb 9
|
||
doi: 10.1007/s00125-023-06068-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38334818" target="_blank">38334818</a><a href="/pmc/articles/PMC10904471" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29764898">Clinical Presentation and Outcome in a Contemporary Cohort of Patients With Acute Myocarditis: Multicenter Lombardy Registry.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ammirati E,
|
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Cipriani M,
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Moro C,
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Raineri C,
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Pini D,
|
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Sormani P,
|
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Mantovani R,
|
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Varrenti M,
|
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Pedrotti P,
|
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Conca C,
|
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Mafrici A,
|
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Grosu A,
|
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Briguglia D,
|
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Guglielmetto S,
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Perego GB,
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Colombo S,
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Caico SI,
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Giannattasio C,
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Maestroni A,
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Carubelli V,
|
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Metra M,
|
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Lombardi C,
|
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Campodonico J,
|
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Agostoni P,
|
||
Peretto G,
|
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Scelsi L,
|
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Turco A,
|
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Di Tano G,
|
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Campana C,
|
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Belloni A,
|
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Morandi F,
|
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Mortara A,
|
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Cirò A,
|
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Senni M,
|
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Gavazzi A,
|
||
Frigerio M,
|
||
Oliva F,
|
||
Camici PG;
|
||
Registro Lombardo delle Miocarditi</span><br />
|
||
<span class="medgenPMjournal">Circulation</span>
|
||
2018 Sep 11;138(11):1088-1099.
|
||
doi: 10.1161/CIRCULATIONAHA.118.035319.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29764898" target="_blank">29764898</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28571635">β-Blockers and Mortality After Acute Myocardial Infarction in Patients Without Heart Failure or Ventricular Dysfunction.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dondo TB,
|
||
Hall M,
|
||
West RM,
|
||
Jernberg T,
|
||
Lindahl B,
|
||
Bueno H,
|
||
Danchin N,
|
||
Deanfield JE,
|
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Hemingway H,
|
||
Fox KAA,
|
||
Timmis AD,
|
||
Gale CP</span><br />
|
||
<span class="medgenPMjournal">J Am Coll Cardiol</span>
|
||
2017 Jun 6;69(22):2710-2720.
|
||
doi: 10.1016/j.jacc.2017.03.578.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28571635" target="_blank">28571635</a><a href="/pmc/articles/PMC5457288" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27040723">Coronary-Artery Bypass Surgery in Patients with Ischemic Cardiomyopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Velazquez EJ,
|
||
Lee KL,
|
||
Jones RH,
|
||
Al-Khalidi HR,
|
||
Hill JA,
|
||
Panza JA,
|
||
Michler RE,
|
||
Bonow RO,
|
||
Doenst T,
|
||
Petrie MC,
|
||
Oh JK,
|
||
She L,
|
||
Moore VL,
|
||
Desvigne-Nickens P,
|
||
Sopko G,
|
||
Rouleau JL;
|
||
STICHES Investigators</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2016 Apr 21;374(16):1511-20.
|
||
Epub 2016 Apr 3
|
||
doi: 10.1056/NEJMoa1602001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27040723" target="_blank">27040723</a><a href="/pmc/articles/PMC4938005" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15753115">The effect of cardiac resynchronization on morbidity and mortality in heart failure.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cleland JG,
|
||
Daubert JC,
|
||
Erdmann E,
|
||
Freemantle N,
|
||
Gras D,
|
||
Kappenberger L,
|
||
Tavazzi L;
|
||
Cardiac Resynchronization-Heart Failure (CARE-HF) Study Investigators</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2005 Apr 14;352(15):1539-49.
|
||
Epub 2005 Mar 7
|
||
doi: 10.1056/NEJMoa050496.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15753115" target="_blank">15753115</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Left%20ventricular%20systolic%20dysfunction%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1529)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39231876">The promise of machine learning models in cardiovascular risk prediction : Machine learning predictions of the adverse events of different treatments in patients with ischemic left ventricular systolic dysfunction.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cardona A</span><br />
|
||
<span class="medgenPMjournal">Intern Emerg Med</span>
|
||
2024 Oct;19(7):1805-1806.
|
||
Epub 2024 Sep 4
|
||
doi: 10.1007/s11739-024-03759-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39231876" target="_blank">39231876</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37321694">Pacing-Induced Cardiomyopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Khurshid S,
|
||
Frankel DS</span><br />
|
||
<span class="medgenPMjournal">Cardiol Clin</span>
|
||
2023 Aug;41(3):449-461.
|
||
doi: 10.1016/j.ccl.2023.03.010.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37321694" target="_blank">37321694</a><a href="/pmc/articles/PMC11194687" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35156906">Irreversible Cabozantinib-induced left ventricular systolic dysfunction, a potentially novel observation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Verran C,
|
||
Guha K</span><br />
|
||
<span class="medgenPMjournal">J Chemother</span>
|
||
2023 Feb;35(1):72-74.
|
||
Epub 2022 Feb 14
|
||
doi: 10.1080/1120009X.2022.2033567.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35156906" target="_blank">35156906</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35863062">Coronary Jeopardy Score Predicts Ischemic Etiology in Patients With Left Ventricular Systolic Dysfunction.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Morgan H,
|
||
Ryan M,
|
||
Briceno N,
|
||
Modi B,
|
||
Rahman H,
|
||
Arnold S,
|
||
Villa A,
|
||
Chiribiri A,
|
||
Perera D</span><br />
|
||
<span class="medgenPMjournal">J Invasive Cardiol</span>
|
||
2022 Sep;34(9):E683-E685.
|
||
Epub 2022 Jul 22
|
||
doi: 10.25270/jic/21.00435.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35863062" target="_blank">35863062</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34689900">Pacing-Induced Cardiomyopathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Khurshid S,
|
||
Frankel DS</span><br />
|
||
<span class="medgenPMjournal">Card Electrophysiol Clin</span>
|
||
2021 Dec;13(4):741-753.
|
||
Epub 2021 Sep 23
|
||
doi: 10.1016/j.ccep.2021.06.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34689900" target="_blank">34689900</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Left%20ventricular%20systolic%20dysfunction%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1360)</a></div></div>
|
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|
||
|
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<div class="portlet mgSection" id="ID_104">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/38334818">Epidemiology of heart failure in diabetes: a disease in disguise.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hoek AG,
|
||
Dal Canto E,
|
||
Wenker E,
|
||
Bindraban N,
|
||
Handoko ML,
|
||
Elders PJM,
|
||
Beulens JWJ</span><br />
|
||
<span class="medgenPMjournal">Diabetologia</span>
|
||
2024 Apr;67(4):574-601.
|
||
Epub 2024 Feb 9
|
||
doi: 10.1007/s00125-023-06068-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38334818" target="_blank">38334818</a><a href="/pmc/articles/PMC10904471" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31732195">Left Ventricular Systolic Dysfunction and Cardiovascular Outcomes in Tetralogy of Fallot: Systematic Review and Meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Egbe AC,
|
||
Adigun R,
|
||
Anand V,
|
||
West CP,
|
||
Montori VM,
|
||
Murad MH,
|
||
Akintoye E,
|
||
Osman K,
|
||
Connolly HM</span><br />
|
||
<span class="medgenPMjournal">Can J Cardiol</span>
|
||
2019 Dec;35(12):1784-1790.
|
||
Epub 2019 Aug 8
|
||
doi: 10.1016/j.cjca.2019.07.634.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31732195" target="_blank">31732195</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28245343">Eplerenone for hypertension.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tam TS,
|
||
Wu MH,
|
||
Masson SC,
|
||
Tsang MP,
|
||
Stabler SN,
|
||
Kinkade A,
|
||
Tung A,
|
||
Tejani AM</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2017 Feb 28;2(2):CD008996.
|
||
doi: 10.1002/14651858.CD008996.pub2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28245343" target="_blank">28245343</a><a href="/pmc/articles/PMC6464701" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21878135">Heart failure.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McKelvie RS</span><br />
|
||
<span class="medgenPMjournal">BMJ Clin Evid</span>
|
||
2011 Aug 30;2011
|
||
<span class="bold">PMID: </span><a href="/pubmed/21878135" target="_blank">21878135</a><a href="/pmc/articles/PMC3275321" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21718583">Heart failure.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McKelvie RS</span><br />
|
||
<span class="medgenPMjournal">BMJ Clin Evid</span>
|
||
2010 Feb 25;2010
|
||
<span class="bold">PMID: </span><a href="/pubmed/21718583" target="_blank">21718583</a><a href="/pmc/articles/PMC2907608" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Left%20ventricular%20systolic%20dysfunction%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (68)</a></div></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22left%20ventricular%20systolic%20dysfunction%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Left%20ventricular%20systolic%20dysfunction%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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