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<meta name="keywords" content="C1258215, disease or syndrome, gastrointestinal atony, ileus, ileus of intestine, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Acute obstruction of the intestines preventing passage of the contents of the intestines." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
UID=219874
ConceptID=C1258215
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Ileus</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>219874</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1258215</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
<td>Gastrointestinal atony; ileus; ileus of intestine</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0002595">HP:0002595</a></td></tr>
<tr><td>Monarch Initiative:</td>
<td><a href="https://monarchinitiative.org/disease/MONDO:0004567" target="_blank">MONDO:0004567</a></td></tr>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">Acute obstruction of the intestines preventing passage of the contents of the intestines. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Ileus</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/21047" ref="tree=MeSH" title="MedGen record for Pathological Conditions, Signs and Symptoms">Pathological Conditions, Signs and Symptoms</a></span><ul><li><span class="TLline"><a href="/medgen/19974" ref="tree=MeSH" title="MedGen record for Clinical finding">Clinical finding</a></span><ul><li><span class="TLline"><a href="/medgen/272632" ref="tree=MeSH" title="MedGen record for Finding by Site or System">Finding by Site or System</a></span><ul><li><span class="TLline"><a href="/medgen/272669" ref="tree=MeSH" title="MedGen record for Digestive system finding">Digestive system finding</a></span><ul><li><span class="TLline"><a href="/medgen/437967" ref="tree=MeSH" title="MedGen record for Digestive System Obstruction">Digestive System Obstruction</a></span><ul><li><span class="TLline"><a href="/medgen/43933" ref="tree=MeSH" title="MedGen record for Intestinal obstruction">Intestinal obstruction</a></span><ul><li><span class="matched_ds">Ileus</span><ul><li><span class="TLline"><a href="/medgen/5864" ref="tree=MeSH" title="MedGen record for Intestinal pseudo-obstruction">Intestinal pseudo-obstruction</a></span><ul><li><span class="TLline"><a href="/medgen/3167" ref="tree=MeSH" title="MedGen record for Colonic pseudo-obstruction">Colonic pseudo-obstruction</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/98322" ref="tree=MeSH" title="MedGen record for Mechanical ileus">Mechanical ileus</a></span><ul><li><span class="TLline"><a href="/medgen/473705" ref="tree=MeSH" title="MedGen record for Meconium ileus">Meconium ileus</a></span><ul><li><span class="TLline"><a href="/medgen/639765" ref="tree=MeSH" title="MedGen record for Cystic fibrosis associated meconium ileus">Cystic fibrosis associated meconium ileus</a></span></li><li><span class="TLline"><a href="/medgen/1390359" ref="tree=MeSH" title="MedGen record for Intestinal obstruction in the newborn due to guanylate cyclase 2C deficiency">Intestinal obstruction in the newborn due to guanylate cyclase 2C deficiency</a></span></li></ul></li></ul></li><li><span class="TLline"><a href="/medgen/18293" ref="tree=MeSH" title="MedGen record for Paralytic ileus">Paralytic ileus</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_112">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln clinfeat">
<div class="divPopper rprt" id="rdis_41393"><div><strong>Cystic fibrosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>41393</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0010674</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Cystic fibrosis (CF) is a multisystem disease affecting epithelia of the respiratory tract, exocrine pancreas, intestine, hepatobiliary system, and exocrine sweat glands. Morbidities include recurrent sinusitis and bronchitis, progressive obstructive pulmonary disease with bronchiectasis, exocrine pancreatic deficiency and malnutrition, pancreatitis, gastrointestinal manifestations (meconium ileus, rectal prolapse, distal intestinal obstructive syndrome), liver disease, diabetes, male infertility due to hypoplasia or aplasia of the vas deferens, and reduced fertility or infertility in some women. Pulmonary disease is the major cause of morbidity and mortality in CF.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/41393">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_83339"><div><strong>Insulin-dependent diabetes mellitus secretory diarrhea syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>83339</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0342288</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked) syndrome is characterized by systemic autoimmunity, typically beginning in the first year of life, which includes the triad of enteropathy (manifesting as malabsorption and watery diarrhea), endocrinopathy (most commonly type 1 insulin-dependent diabetes mellitus), and eczematous dermatitis. In addition to these manifestations, many children have other autoimmune phenomena including cytopenias, autoimmune hepatitis, nephropathy, lymphadenopathy, splenomegaly, alopecia, arthritis, and interstitial lung disease related to immune dysregulation. Fetal presentation of IPEX syndrome includes hydrops, echogenic bowel, skin desquamation, intrauterine growth deficiency, and fetal akinesia. Without aggressive immunosuppression or hematopoietic stem cell transplantation (HSCT), the majority of affected males will die within the first one to two years of life from metabolic derangements, severe malabsorption, or sepsis. Individuals with a milder phenotype have survived into the second or third decade of life, but this is uncommon.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/83339">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_373160"><div><strong>PCWH syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>373160</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1836727</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">PCWH syndrome is a complex neurocristopathy that includes features of 4 distinct syndromes: peripheral demyelinating neuropathy (see 118200), central dysmyelination, Waardenburg syndrome, and Hirschsprung disease (see 142623) (Inoue et al., 2004). Inoue et al. (2004) proposed the acronym PCWH for this disorder.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/373160">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_337451"><div><strong>Creatine transporter deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>337451</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information."><span class="highlight" style="background-color:">C1845862</span></a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">The creatine deficiency disorders (CDDs), inborn errors of creatine metabolism and transport, comprise three disorders: the creatine biosynthesis disorders guanidinoacetate methyltransferase (GAMT) deficiency and L-arginine:glycine amidinotransferase (AGAT) deficiency; and creatine transporter (CRTR) deficiency. Developmental delay and cognitive dysfunction or intellectual disability and speech-language disorder are common to all three CDDs. Onset of clinical manifestations of GAMT deficiency (reported in ~130 individuals) is between ages three months and two years; in addition to developmental delays, the majority of individuals have epilepsy and develop a behavior disorder (e.g., hyperactivity, autism, or self-injurious behavior), and about 30% have movement disorder. AGAT deficiency has been reported in 16 individuals; none have had epilepsy or movement disorders. Clinical findings of CRTR deficiency in affected males (reported in ~130 individuals) in addition to developmental delays include epilepsy (variable seizure types and may be intractable) and behavior disorders (e.g., attention deficit and/or hyperactivity, autistic features, impulsivity, social anxiety), hypotonia, and (less commonly) a movement disorder. Poor weight gain with constipation and prolonged QTc on EKG have been reported. While mild-to-moderate intellectual disability is commonly observed up to age four years, the majority of adult males with CRTR deficiency have been reported to have severe intellectual disability. Females heterozygous for CRTR deficiency are typically either asymptomatic or have mild intellectual disability, although a more severe phenotype resembling the male phenotype has been reported.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/337451">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_412871"><div><strong>Congenital generalized lipodystrophy type 4</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>412871</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C2750069</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Berardinelli-Seip congenital lipodystrophy (BSCL) is usually diagnosed at birth or soon thereafter. Because of the absence of functional adipocytes, lipid is stored in other tissues, including muscle and liver. Affected individuals develop insulin resistance and approximately 25%-35% develop diabetes mellitus between ages 15 and 20 years. Hepatomegaly secondary to hepatic steatosis and skeletal muscle hypertrophy occur in all affected individuals. Hypertrophic cardiomyopathy is reported in 20%-25% of affected individuals and is a significant cause of morbidity from cardiac failure and early mortality.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/412871">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_1824043"><div><strong>Cortical dysplasia, complex, with other brain malformations 11</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1824043</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C5774270</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Complex cortical dysplasia with other brain malformations-11 (CDCBM11) is an autosomal recessive disorder characterized by dilated ventricles and reduced white matter and associated with axonal developmental defects (Qian et al., 2022).&#13; For a discussion of genetic heterogeneity of CDCBM, see CDCBM1 (614039).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/1824043">Condition Record</a></div></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_412871" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Congenital generalized lipodystrophy type 4</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1824043" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cortical dysplasia, complex, with other brain malformations 11</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_337451" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Creatine transporter deficiency</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_41393" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cystic fibrosis</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_83339" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Insulin-dependent diabetes mellitus secretory diarrhea syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_373160" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">PCWH syndrome</a></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/38276922">AGA Clinical Practice Update on Diet and Nutritional Therapies in Patients With Inflammatory Bowel Disease: Expert Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Hashash JG,
Elkins J,
Lewis JD,
Binion DG</span><br />
<span class="medgenPMjournal">Gastroenterology</span>
2024 Mar;166(3):521-532.
Epub 2024 Jan 23
doi: 10.1053/j.gastro.2023.11.303.
<span class="bold">PMID: </span><a href="/pubmed/38276922" target="_blank">38276922</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32003951">Clostridioides difficile Infection: Update on Management.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Mounsey A,
Lacy Smith K,
Reddy VC,
Nickolich S</span><br />
<span class="medgenPMjournal">Am Fam Physician</span>
2020 Feb 1;101(3):168-175.
<span class="bold">PMID: </span><a href="/pubmed/32003951" target="_blank">32003951</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31479658">American Gastroenterological Association Clinical Practice Update: Management of Pancreatic Necrosis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Baron TH,
DiMaio CJ,
Wang AY,
Morgan KA</span><br />
<span class="medgenPMjournal">Gastroenterology</span>
2020 Jan;158(1):67-75.e1.
Epub 2019 Aug 31
doi: 10.1053/j.gastro.2019.07.064.
<span class="bold">PMID: </span><a href="/pubmed/31479658" target="_blank">31479658</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22ileus%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (448)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/39341622">Postoperative Complications.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Nye HE,
Shen EP,
Baig F</span><br />
<span class="medgenPMjournal">Med Clin North Am</span>
2024 Nov;108(6):1201-1214.
Epub 2024 Jun 8
doi: 10.1016/j.mcna.2024.04.011.
<span class="bold">PMID: </span><a href="/pubmed/39341622" target="_blank">39341622</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36932773">Effect of early physical therapy interventions on post-operative ileus following abdominal hysterectomy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Zia Z,
Riaz H,
Imtiaz I</span><br />
<span class="medgenPMjournal">J Pak Med Assoc</span>
2023 Mar;73(3):650-652.
doi: 10.47391/JPMA.5447.
<span class="bold">PMID: </span><a href="/pubmed/36932773" target="_blank">36932773</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35048360">Postoperative ileus: A pharmacological perspective.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Buscail E,
Deraison C</span><br />
<span class="medgenPMjournal">Br J Pharmacol</span>
2022 Jul;179(13):3283-3305.
Epub 2022 Feb 15
doi: 10.1111/bph.15800.
<span class="bold">PMID: </span><a href="/pubmed/35048360" target="_blank">35048360</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32683979">Post-cholecystectomy Gallstone Ileus.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Meier J,
Guzzetta AA,
Huerta S</span><br />
<span class="medgenPMjournal">Am Surg</span>
2020 Jun;86(6):675-684.
doi: 10.1177/0003134820923296.
<span class="bold">PMID: </span><a href="/pubmed/32683979" target="_blank">32683979</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27666979">Postoperative ileus: Pathophysiology, incidence, and prevention.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Venara A,
Neunlist M,
Slim K,
Barbieux J,
Colas PA,
Hamy A,
Meurette G</span><br />
<span class="medgenPMjournal">J Visc Surg</span>
2016 Dec;153(6):439-446.
Epub 2016 Sep 23
doi: 10.1016/j.jviscsurg.2016.08.010.
<span class="bold">PMID: </span><a href="/pubmed/27666979" target="_blank">27666979</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ileus%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4182)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/38957962">Ileus at Altitude.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ebert-Santos C,
Campos A</span><br />
<span class="medgenPMjournal">High Alt Med Biol</span>
2024 Dec;25(4):342-344.
Epub 2024 Jul 3
doi: 10.1089/ham.2023.0132.
<span class="bold">PMID: </span><a href="/pubmed/38957962" target="_blank">38957962</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37097249">Gallstone ileus.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Shanmugarajah I,
Letting TS,
Rustad H</span><br />
<span class="medgenPMjournal">Tidsskr Nor Laegeforen</span>
2023 Apr 25;143(6)
Epub 2023 Apr 11
doi: 10.4045/tidsskr.22.0452.
<span class="bold">PMID: </span><a href="/pubmed/37097249" target="_blank">37097249</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28818187">Ileus in Adults.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Vilz TO,
Stoffels B,
Strassburg C,
Schild HH,
Kalff JC</span><br />
<span class="medgenPMjournal">Dtsch Arztebl Int</span>
2017 Jul 24;114(29-30):508-518.
doi: 10.3238/arztebl.2017.0508.
<span class="bold">PMID: </span><a href="/pubmed/28818187" target="_blank">28818187</a><a href="/pmc/articles/PMC5569564" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28433486">Gallstone ileus: An overview of the literature.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ploneda-Valencia CF,
Gallo-Morales M,
Rinchon C,
Navarro-Muñiz E,
Bautista-López CA,
de la Cerda-Trujillo LF,
Rea-Azpeitia LA,
López-Lizarraga CR</span><br />
<span class="medgenPMjournal">Rev Gastroenterol Mex</span>
2017 Jul-Sep;82(3):248-254.
Epub 2017 Apr 19
doi: 10.1016/j.rgmx.2016.07.006.
<span class="bold">PMID: </span><a href="/pubmed/28433486" target="_blank">28433486</a></div>
<div class="nl"><a target="_blank" href="/pubmed/26281633">Postoperative Ileus.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Katrancha ED,
George NM</span><br />
<span class="medgenPMjournal">Medsurg Nurs</span>
2014 Nov-Dec;23(6):387-90, 413.
<span class="bold">PMID: </span><a href="/pubmed/26281633" target="_blank">26281633</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ileus%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2578)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/36932773">Effect of early physical therapy interventions on post-operative ileus following abdominal hysterectomy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Zia Z,
Riaz H,
Imtiaz I</span><br />
<span class="medgenPMjournal">J Pak Med Assoc</span>
2023 Mar;73(3):650-652.
doi: 10.47391/JPMA.5447.
<span class="bold">PMID: </span><a href="/pubmed/36932773" target="_blank">36932773</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31479658">American Gastroenterological Association Clinical Practice Update: Management of Pancreatic Necrosis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Baron TH,
DiMaio CJ,
Wang AY,
Morgan KA</span><br />
<span class="medgenPMjournal">Gastroenterology</span>
2020 Jan;158(1):67-75.e1.
Epub 2019 Aug 31
doi: 10.1053/j.gastro.2019.07.064.
<span class="bold">PMID: </span><a href="/pubmed/31479658" target="_blank">31479658</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25819420">Postoperative ileus: Recent developments in pathophysiology and management.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Bragg D,
El-Sharkawy AM,
Psaltis E,
Maxwell-Armstrong CA,
Lobo DN</span><br />
<span class="medgenPMjournal">Clin Nutr</span>
2015 Jun;34(3):367-76.
Epub 2015 Jan 31
doi: 10.1016/j.clnu.2015.01.016.
<span class="bold">PMID: </span><a href="/pubmed/25819420" target="_blank">25819420</a></div>
<div class="nl"><a target="_blank" href="/pubmed/15882122">Alvimopan.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Neary P,
Delaney CP</span><br />
<span class="medgenPMjournal">Expert Opin Investig Drugs</span>
2005 Apr;14(4):479-88.
doi: 10.1517/13543784.14.4.479.
<span class="bold">PMID: </span><a href="/pubmed/15882122" target="_blank">15882122</a></div>
<div class="nl"><a target="_blank" href="/pubmed/12614092">A critical overview of homeopathy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Jonas WB,
Kaptchuk TJ,
Linde K</span><br />
<span class="medgenPMjournal">Ann Intern Med</span>
2003 Mar 4;138(5):393-9.
doi: 10.7326/0003-4819-138-5-200303040-00009.
<span class="bold">PMID: </span><a href="/pubmed/12614092" target="_blank">12614092</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ileus%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (3592)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/27666979">Postoperative ileus: Pathophysiology, incidence, and prevention.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Venara A,
Neunlist M,
Slim K,
Barbieux J,
Colas PA,
Hamy A,
Meurette G</span><br />
<span class="medgenPMjournal">J Visc Surg</span>
2016 Dec;153(6):439-446.
Epub 2016 Sep 23
doi: 10.1016/j.jviscsurg.2016.08.010.
<span class="bold">PMID: </span><a href="/pubmed/27666979" target="_blank">27666979</a></div>
<div class="nl"><a target="_blank" href="/pubmed/21477397">Appendicitis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">D'Souza N</span><br />
<span class="medgenPMjournal">BMJ Clin Evid</span>
2011 Jan 7;2011
<span class="bold">PMID: </span><a href="/pubmed/21477397" target="_blank">21477397</a><a href="/pmc/articles/PMC3275312" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/18838459">Gallstone ileus.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Koulaouzidis A,
Moschos J,
Bhat S,
Gopal K</span><br />
<span class="medgenPMjournal">CMAJ</span>
2008 Oct 7;179(8):859.
doi: 10.1503/cmaj.070029.
<span class="bold">PMID: </span><a href="/pubmed/18838459" target="_blank">18838459</a><a href="/pmc/articles/PMC2553856" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/15276337">Postoperative ileus.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Nunley JC,
FitzHarris GP</span><br />
<span class="medgenPMjournal">Curr Surg</span>
2004 Jul-Aug;61(4):341-5.
doi: 10.1016/j.cursur.2003.07.008.
<span class="bold">PMID: </span><a href="/pubmed/15276337" target="_blank">15276337</a></div>
<div class="nl"><a target="_blank" href="/pubmed/1403517">Neonatal gastrointestinal perforations.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">St-Vil D,
LeBouthillier G,
Luks FI,
Bensoussan AL,
Blanchard H,
Youssef S</span><br />
<span class="medgenPMjournal">J Pediatr Surg</span>
1992 Oct;27(10):1340-2.
doi: 10.1016/0022-3468(92)90292-f.
<span class="bold">PMID: </span><a href="/pubmed/1403517" target="_blank">1403517</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ileus%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1969)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/35638775">Successful gallstone ileus treatment by endoscopy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Guerro Moya A,
Couto Wörner I,
Alonso Aguirre PA</span><br />
<span class="medgenPMjournal">Rev Esp Enferm Dig</span>
2022 Dec;114(12):754-755.
doi: 10.17235/reed.2022.8898/2022.
<span class="bold">PMID: </span><a href="/pubmed/35638775" target="_blank">35638775</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32580530">Ileus in the critically ill: causes, treatment and prevention.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ariès P,
Huet O</span><br />
<span class="medgenPMjournal">Minerva Anestesiol</span>
2020 Sep;86(9):974-983.
Epub 2020 Jun 23
doi: 10.23736/S0375-9393.20.14778-3.
<span class="bold">PMID: </span><a href="/pubmed/32580530" target="_blank">32580530</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31297663">Dysautonomia in Guillain-Barré Syndrome: Prevalence, Clinical Spectrum, and Outcomes.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Chakraborty T,
Kramer CL,
Wijdicks EFM,
Rabinstein AA</span><br />
<span class="medgenPMjournal">Neurocrit Care</span>
2020 Feb;32(1):113-120.
doi: 10.1007/s12028-019-00781-w.
<span class="bold">PMID: </span><a href="/pubmed/31297663" target="_blank">31297663</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27467866">Gallstone ileus: literature review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Artioli G,
Muri M,
Praticò FE,
Marcantoni EA,
Gazzani SE,
Lana S,
Bacchini E,
Capretti G,
Muri M,
Torri T</span><br />
<span class="medgenPMjournal">Acta Biomed</span>
2016 Jul 28;87 Suppl 3:40-4.
<span class="bold">PMID: </span><a href="/pubmed/27467866" target="_blank">27467866</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25548480">Enterolithiasis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gurvits GE,
Lan G</span><br />
<span class="medgenPMjournal">World J Gastroenterol</span>
2014 Dec 21;20(47):17819-29.
doi: 10.3748/wjg.v20.i47.17819.
<span class="bold">PMID: </span><a href="/pubmed/25548480" target="_blank">25548480</a><a href="/pmc/articles/PMC4273132" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Ileus%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1802)</a></div></div>
</div>
<div class="portlet mgSection" id="ID_104">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">
<div class="nl"><a target="_blank" href="/pubmed/37246124">Complications After Radical Cystectomy: A Systematic Review and Meta-analysis of Randomized Controlled Trials with a Meta-regression Analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Katsimperis S,
Tzelves L,
Tandogdu Z,
Ta A,
Geraghty R,
Bellos T,
Manolitsis I,
Pyrgidis N,
Schulz GB,
Sridhar A,
Shaw G,
Kelly J,
Skolarikos A</span><br />
<span class="medgenPMjournal">Eur Urol Focus</span>
2023 Nov;9(6):920-929.
Epub 2023 May 26
doi: 10.1016/j.euf.2023.05.002.
<span class="bold">PMID: </span><a href="/pubmed/37246124" target="_blank">37246124</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35034068">The Comparison of eTEP and IPOM in Ventral and Incisional Hernia Repair: A Systematic Review and Meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Li J,
Wang Y,
Wu L</span><br />
<span class="medgenPMjournal">Surg Laparosc Endosc Percutan Tech</span>
2022 Jan 17;32(2):252-258.
doi: 10.1097/SLE.0000000000001035.
<span class="bold">PMID: </span><a href="/pubmed/35034068" target="_blank">35034068</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29864216">Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery in adults.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Weibel S,
Jelting Y,
Pace NL,
Helf A,
Eberhart LH,
Hahnenkamp K,
Hollmann MW,
Poepping DM,
Schnabel A,
Kranke P</span><br />
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
2018 Jun 4;6(6):CD009642.
doi: 10.1002/14651858.CD009642.pub3.
<span class="bold">PMID: </span><a href="/pubmed/29864216" target="_blank">29864216</a><a href="/pmc/articles/PMC6513586" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28439845">A Systematic Review of the Clinical Presentation, Diagnosis, and Treatment of Small Bowel Obstruction.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Rami Reddy SR,
Cappell MS</span><br />
<span class="medgenPMjournal">Curr Gastroenterol Rep</span>
2017 Jun;19(6):28.
doi: 10.1007/s11894-017-0566-9.
<span class="bold">PMID: </span><a href="/pubmed/28439845" target="_blank">28439845</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27174045">Prucalopride: For functional constipation only?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Bellini M,
Gambaccini D,
Bassotti G</span><br />
<span class="medgenPMjournal">Tech Coloproctol</span>
2016 Jul;20(7):433-6.
Epub 2016 May 12
doi: 10.1007/s10151-016-1477-8.
<span class="bold">PMID: </span><a href="/pubmed/27174045" target="_blank">27174045</a></div>
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