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<meta name="keywords" content="C0042133, benign uterine leiomyomas, body of uterus fibroid, body of uterus leiomyoma, corpus uteri fibroid, corpus uteri leiomyoma, fibroid of body of uterus, fibroid of corpus uteri, fibroid of the body of uterus, fibroid of the corpus uteri, fibroid of the uterine body, fibroid of the uterine corpus, fibroid of uterine body, fibroid of uterine corpus, fibroid uterus, fibroid, uterine, fibroids, fibroids, uterine, fibroma, uterine, fibromas, uterine, leiomyoma, leiomyoma of body of uterus, leiomyoma of corpus uteri, leiomyoma of the body of uterus, leiomyoma of the corpus uteri, leiomyoma of the uterine body, leiomyoma of the uterine corpus, leiomyoma of uterine body, leiomyoma of uterine corpus, leiomyoma of uterus, leiomyoma, uterine, neoplastic process, plexiform leiomyoma, ul, uterine body fibroid, uterine body leiomyoma, uterine corpus fibroid, uterine corpus leiomyoma, uterine corpus leiomyomata, uterine fibroid, uterine fibroids, uterine fibroma, uterine fibromas, uterine leiomyoma, uterine leiomyoma - fibroids, uterine leiomyomas, uterine leiomyomas, benign, uterine leiomyomata, uterus fibroma, uterus, fibroid, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Uterine leiomyoma (UL), commonly known as fibroids, are benign tumors of the uterine myometrium. They represent the most prevalent pelvic tumors in women and are found in more than 75% of women of reproductive age. Approximately 20 to 25% of women with UL exhibit symptoms including menorrhagia, infertility, pelvic pain, and a range of complications during pregnancy. UL are the leading cause for hysterectomy in the United States, accounting for 30% of all hysterectomies (summary by Eggert et al., 2012)." /><meta name="robots" content="index,nofollow,noarchive" />
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<title>Uterine leiomyoma (Concept Id: C0042133)
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<!--
UID=21801
ConceptID=C0042133
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Uterine leiomyoma<span class="h1sub">(UL)</span></div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>21801</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0042133</a></dd><dt><span class="dotprefix"></span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
<td>UL; Uterine corpus leiomyoma</td></tr>
<tr><td><span class="bold">SNOMED CT: </span></td>
<td>Uterine leiomyoma (95315005); Leiomyoma of uterus (95315005); Leiomyoma (146801000119103); Uterine fibroid (95315005); Uterine fibroids (95315005); Uterine leiomyoma - fibroids (95315005); Fibroids (95315005); Leiomyoma of body of uterus (95315005); Fibroid uterus (95315005)</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0000131">HP:0000131</a></td></tr>
<tr><td>Monarch Initiative:</td>
<td><a href="https://monarchinitiative.org/disease/MONDO:0007886" target="_blank">MONDO:0007886</a></td></tr>
<tr><td>OMIM<span class="superscript">®</span>:</td>
<td><a href="https://omim.org/entry/150699" target="_blank">150699</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">Uterine leiomyoma (UL), commonly known as fibroids, are benign tumors of the uterine myometrium. They represent the most prevalent pelvic tumors in women and are found in more than 75% of women of reproductive age. Approximately 20 to 25% of women with UL exhibit symptoms including menorrhagia, infertility, pelvic pain, and a range of complications during pregnancy. UL are the leading cause for hysterectomy in the United States, accounting for 30% of all hysterectomies (summary by Eggert et al., 2012). [from <a title="Online Mendelian Inheritance in Man" href="http://www.omim.org" class="defSource" target="_blank">OMIM</a>]</div>
</div>
<div class="portlet mgSection" id="ID_102">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_features">Clinical features</h1><a sid="102" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln clinfeat"><strong>From HPO</strong><br />
<div class="divPopper rprt" id="clin_21801"><div><strong>Uterine leiomyoma</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>21801</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0042133</a></dd><dt><span class="dotprefix"></span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
<div class="spaceAbove">Uterine leiomyoma (UL), commonly known as fibroids, are benign tumors of the uterine myometrium. They represent the most prevalent pelvic tumors in women and are found in more than 75% of women of reproductive age. Approximately 20 to 25% of women with UL exhibit symptoms including menorrhagia, infertility, pelvic pain, and a range of complications during pregnancy. UL are the leading cause for hysterectomy in the United States, accounting for 30% of all hysterectomies (summary by Eggert et al., 2012).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/21801">Feature record</a> | <a href="/medgen?term=%22Uterine%20leiomyoma%22%5BClinical%20Features%5D%20OR%2021801%5Buid%5D">Search on this feature</a></div></div><div class="TreeLite"><ul><li><span class="TLline">Neoplasm</span><ul><li class="TLline">
<span class="TLline"><a title="click for more information" class="jig-ncbipopper" href="#clin_21801" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Uterine leiomyoma</a></span></li></ul></li></ul></div></div>
</div>
<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0042133[DISCUI]&amp;test_type=Clinical" ref="ncbi_uid=21801">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet Ocolor" title="OMIM"><a ref="ncbi_uid=21801" target="_blank" href="/omim/150699">O</a></span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&amp;from_uid=21801" ref="ncbi_uid=21801">V</a></span></span><span class="TLline">Uterine leiomyoma</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/61253" ref="tree=MeSH" title="MedGen record for Reproductive system disorder">Reproductive system disorder</a></span><ul><li><span class="TLline"><a href="/medgen/65928" ref="tree=MeSH" title="MedGen record for Female reproductive system disorder">Female reproductive system disorder</a></span><ul><li><span class="TLline"><a href="/medgen/9004" ref="tree=MeSH" title="MedGen record for Female reproductive system neoplasm">Female reproductive system neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/12030" ref="tree=MeSH" title="MedGen record for Neoplasm of uterus">Neoplasm of uterus</a></span><ul><li><span class="TLline"><a href="/medgen/226810" ref="tree=MeSH" title="MedGen record for Corpus uteri neoplasm">Corpus uteri neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/57808" ref="tree=MeSH" title="MedGen record for Benign neoplasm of corpus uteri">Benign neoplasm of corpus uteri</a></span><ul><li><span class="matched_ds">Uterine leiomyoma</span><ul><li><span class="TLline"><a href="/medgen/307261" ref="tree=MeSH" title="MedGen record for Benign metastasizing leiomyoma">Benign metastasizing leiomyoma</a></span></li><li><span class="TLline"><a href="/medgen/83417" ref="tree=MeSH" title="MedGen record for Intravenous leiomyomatosis">Intravenous leiomyomatosis</a></span></li><li><span class="TLline"><a href="/medgen/274364" ref="tree=MeSH" title="MedGen record for Uterine corpus apoplectic leiomyoma">Uterine corpus apoplectic leiomyoma</a></span></li><li><span class="TLline"><a href="/medgen/275555" ref="tree=MeSH" title="MedGen record for Uterine corpus bizarre leiomyoma">Uterine corpus bizarre leiomyoma</a></span></li><li><span class="TLline"><a href="/medgen/276938" ref="tree=MeSH" title="MedGen record for Uterine corpus cellular leiomyoma">Uterine corpus cellular leiomyoma</a></span></li><li><span class="TLline"><a href="/medgen/56255" ref="tree=MeSH" title="MedGen record for Uterine Corpus Degenerated Leiomyoma">Uterine Corpus Degenerated Leiomyoma</a></span></li><li><span class="TLline"><a href="/medgen/275556" ref="tree=MeSH" title="MedGen record for Uterine corpus diffuse leiomyomatosis">Uterine corpus diffuse leiomyomatosis</a></span></li><li><span class="TLline"><a href="/medgen/275552" ref="tree=MeSH" title="MedGen record for Uterine corpus dissecting leiomyoma">Uterine corpus dissecting leiomyoma</a></span></li><li><span class="TLline"><a href="/medgen/275554" ref="tree=MeSH" title="MedGen record for Uterine corpus epithelioid leiomyoma">Uterine corpus epithelioid leiomyoma</a></span></li><li><span class="TLline"><a href="/medgen/925581" ref="tree=MeSH" title="MedGen record for Uterine Corpus Hydropic Leiomyoma">Uterine Corpus Hydropic Leiomyoma</a></span></li><li><span class="TLline"><a href="/medgen/274365" ref="tree=MeSH" title="MedGen record for Uterine Corpus Leiomyoma, Mitotically Active Variant">Uterine Corpus Leiomyoma, Mitotically Active Variant</a></span></li><li><span class="TLline"><a href="/medgen/311424" ref="tree=MeSH" title="MedGen record for Uterine corpus lipoleiomyoma">Uterine corpus lipoleiomyoma</a></span></li><li><span class="TLline"><a href="/medgen/275558" ref="tree=MeSH" title="MedGen record for Uterine corpus myxoid leiomyoma">Uterine corpus myxoid leiomyoma</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_112">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln clinfeat">
<div class="divPopper rprt" id="rdis_21801"><div><strong>Uterine leiomyoma</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>21801</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0042133</a></dd><dt><span class="dotprefix"></span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
<div class="spaceAbove">Uterine leiomyoma (UL), commonly known as fibroids, are benign tumors of the uterine myometrium. They represent the most prevalent pelvic tumors in women and are found in more than 75% of women of reproductive age. Approximately 20 to 25% of women with UL exhibit symptoms including menorrhagia, infertility, pelvic pain, and a range of complications during pregnancy. UL are the leading cause for hysterectomy in the United States, accounting for 30% of all hysterectomies (summary by Eggert et al., 2012).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/21801">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_353771"><div><strong>Hereditary leiomyomatosis and renal cell cancer</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>353771</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information."><span class="highlight" style="background-color:">C1708350</span></a></dd><dt><span class="dotprefix"></span></dt><dd>Neoplastic Process</dd></dl></div></div></div>
<div class="spaceAbove">FH tumor predisposition syndrome is characterized by cutaneous leiomyomata, uterine leiomyomata (fibroids), and/or renal tumors. Pheochromocytoma and paraganglioma have also been described in a small number of families. Cutaneous leiomyomata appear as skin-colored to light brown papules or nodules distributed over the trunk and extremities, and occasionally on the face, and appear at a mean age of 30 years, increasing in size and number with age. Uterine leiomyomata tend to be numerous and large; age at diagnosis ranges from 18 to 53 years, with most women experiencing irregular or heavy menstruation and pelvic pain. Renal tumors are usually unilateral, solitary, and aggressive. They are associated with poor survival due to clinical aggressiveness and propensity to metastasize despite small primary tumor size. The median age of detection is approximately age 40 years.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/353771">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_393098"><div><strong>Severe achondroplasia-developmental delay-acanthosis nigricans syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>393098</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C2674173</a></dd><dt><span class="dotprefix"></span></dt><dd>Congenital Abnormality</dd></dl></div></div></div>
<div class="spaceAbove">SADDAN dysplasia (severe achondroplasia with developmental delay and acanthosis nigricans) is a very rare skeletal dysplasia characterized by the constellation of these features. Radiology reveals 'ram's horn' shaped clavicles and reverse bowing of lower limbs. Approximately half of patients die before the fourth week of life secondary to respiratory failure (summary by Zankl et al., 2008).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/393098">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_934686"><div><strong>Familial adenomatous polyposis 4</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>934686</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C4310719</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Familial adenomatous polyposis-4 is an autosomal recessive tumor predisposition syndrome characterized by the development of multiple colonic adenomas in adulthood, often with progression to colorectal cancer. Proliferative lesions in other tissues may also occur (summary by Adam et al., 2016).&#13; For a discussion of genetic heterogeneity of familial adenomatous polyposis, see FAP1 (175100).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/934686">Condition Record</a></div></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_934686" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial adenomatous polyposis 4</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_353771" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hereditary leiomyomatosis and renal cell cancer</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_393098" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Severe achondroplasia-developmental delay-acanthosis nigricans syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_21801" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Uterine leiomyoma</a></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/38790186">Genetic Mechanisms Driving Uterine Leiomyoma Pathobiology, Epidemiology, and Treatment.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ramaiyer MS,
Saad E,
Kurt I,
Borahay MA</span><br />
<span class="medgenPMjournal">Genes (Basel)</span>
2024 Apr 27;15(5)
doi: 10.3390/genes15050558.
<span class="bold">PMID: </span><a href="/pubmed/38790186" target="_blank">38790186</a><a href="/pmc/articles/PMC11121260" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/38066476">A differential diagnosis between uterine leiomyoma and leiomyosarcoma using transcriptome analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kim K,
Kim S,
Ahn T,
Kim H,
Shin SJ,
Choi CH,
Park S,
Kim YB,
No JH,
Suh DH</span><br />
<span class="medgenPMjournal">BMC Cancer</span>
2023 Dec 8;23(1):1215.
doi: 10.1186/s12885-023-11394-0.
<span class="bold">PMID: </span><a href="/pubmed/38066476" target="_blank">38066476</a><a href="/pmc/articles/PMC10709939" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25681841">Clinical management of leiomyoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Owen C,
Armstrong AY</span><br />
<span class="medgenPMjournal">Obstet Gynecol Clin North Am</span>
2015 Mar;42(1):67-85.
Epub 2014 Dec 5
doi: 10.1016/j.ogc.2014.09.009.
<span class="bold">PMID: </span><a href="/pubmed/25681841" target="_blank">25681841</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22uterine%20leiomyoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (88)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/36357960">Long-term Relugolix Combination Therapy for Symptomatic Uterine Leiomyomas.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Al-Hendy A,
Lukes AS,
Poindexter AN 3rd,
Venturella R,
Villarroel C,
McKain L,
Li Y,
Wagman RB,
Stewart EA</span><br />
<span class="medgenPMjournal">Obstet Gynecol</span>
2022 Dec 1;140(6):920-930.
Epub 2022 Nov 2
doi: 10.1097/AOG.0000000000004988.
<span class="bold">PMID: </span><a href="/pubmed/36357960" target="_blank">36357960</a><a href="/pmc/articles/PMC9665945" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34142343">Uterine Fibroids and Pregnancy: How Do They Affect Each Other?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Coutinho LM,
Assis WA,
Spagnuolo-Souza A,
Reis FM</span><br />
<span class="medgenPMjournal">Reprod Sci</span>
2022 Aug;29(8):2145-2151.
Epub 2021 Jun 17
doi: 10.1007/s43032-021-00656-6.
<span class="bold">PMID: </span><a href="/pubmed/34142343" target="_blank">34142343</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29254389">Successes and failures of uterine leiomyoma drug discovery.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ali M,
Chaudhry ZT,
Al-Hendy A</span><br />
<span class="medgenPMjournal">Expert Opin Drug Discov</span>
2018 Feb;13(2):169-177.
Epub 2017 Dec 18
doi: 10.1080/17460441.2018.1417381.
<span class="bold">PMID: </span><a href="/pubmed/29254389" target="_blank">29254389</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28278535">Recent Advances in Uterine Fibroid Etiology.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">McWilliams MM,
Chennathukuzhi VM</span><br />
<span class="medgenPMjournal">Semin Reprod Med</span>
2017 Mar;35(2):181-189.
Epub 2017 Mar 9
doi: 10.1055/s-0037-1599090.
<span class="bold">PMID: </span><a href="/pubmed/28278535" target="_blank">28278535</a><a href="/pmc/articles/PMC5490981" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23200685">Biomarkers in uterine leiomyoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Levy G,
Hill MJ,
Plowden TC,
Catherino WH,
Armstrong AY</span><br />
<span class="medgenPMjournal">Fertil Steril</span>
2013 Mar 15;99(4):1146-52.
Epub 2012 Nov 29
doi: 10.1016/j.fertnstert.2012.10.048.
<span class="bold">PMID: </span><a href="/pubmed/23200685" target="_blank">23200685</a><a href="/pmc/articles/PMC4209733" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Uterine%20leiomyoma%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (678)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/36598763">Comorbidities of Keloid and Hypertrophic Scars Among Participants in UK Biobank.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ung CY,
Warwick A,
Onoufriadis A,
Barker JN,
Parsons M,
McGrath JA,
Shaw TJ,
Dand N</span><br />
<span class="medgenPMjournal">JAMA Dermatol</span>
2023 Feb 1;159(2):172-181.
doi: 10.1001/jamadermatol.2022.5607.
<span class="bold">PMID: </span><a href="/pubmed/36598763" target="_blank">36598763</a><a href="/pmc/articles/PMC9857738" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34142343">Uterine Fibroids and Pregnancy: How Do They Affect Each Other?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Coutinho LM,
Assis WA,
Spagnuolo-Souza A,
Reis FM</span><br />
<span class="medgenPMjournal">Reprod Sci</span>
2022 Aug;29(8):2145-2151.
Epub 2021 Jun 17
doi: 10.1007/s43032-021-00656-6.
<span class="bold">PMID: </span><a href="/pubmed/34142343" target="_blank">34142343</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34053612">Incidental Ovarian and Uterine Findings on Cross-sectional Imaging.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Revzin MV,
Sailer A,
Moshiri M</span><br />
<span class="medgenPMjournal">Radiol Clin North Am</span>
2021 Jul;59(4):661-692.
doi: 10.1016/j.rcl.2021.03.013.
<span class="bold">PMID: </span><a href="/pubmed/34053612" target="_blank">34053612</a></div>
<div class="nl"><a target="_blank" href="/pubmed/12548202">High cumulative incidence of uterine leiomyoma in black and white women: ultrasound evidence.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Baird DD,
Dunson DB,
Hill MC,
Cousins D,
Schectman JM</span><br />
<span class="medgenPMjournal">Am J Obstet Gynecol</span>
2003 Jan;188(1):100-7.
doi: 10.1067/mob.2003.99.
<span class="bold">PMID: </span><a href="/pubmed/12548202" target="_blank">12548202</a></div>
<div class="nl"><a target="_blank" href="/pubmed/11972229">Benign metastasizing leiomyoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Houck WV,
Broderick TJ,
Cohen SA,
Cohen NM</span><br />
<span class="medgenPMjournal">Surg Endosc</span>
2002 Apr;16(4):716.
Epub 2002 Feb 8
doi: 10.1007/s00464-001-4138-5.
<span class="bold">PMID: </span><a href="/pubmed/11972229" target="_blank">11972229</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Uterine%20leiomyoma%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (758)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/36357960">Long-term Relugolix Combination Therapy for Symptomatic Uterine Leiomyomas.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Al-Hendy A,
Lukes AS,
Poindexter AN 3rd,
Venturella R,
Villarroel C,
McKain L,
Li Y,
Wagman RB,
Stewart EA</span><br />
<span class="medgenPMjournal">Obstet Gynecol</span>
2022 Dec 1;140(6):920-930.
Epub 2022 Nov 2
doi: 10.1097/AOG.0000000000004988.
<span class="bold">PMID: </span><a href="/pubmed/36357960" target="_blank">36357960</a><a href="/pmc/articles/PMC9665945" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34142343">Uterine Fibroids and Pregnancy: How Do They Affect Each Other?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Coutinho LM,
Assis WA,
Spagnuolo-Souza A,
Reis FM</span><br />
<span class="medgenPMjournal">Reprod Sci</span>
2022 Aug;29(8):2145-2151.
Epub 2021 Jun 17
doi: 10.1007/s43032-021-00656-6.
<span class="bold">PMID: </span><a href="/pubmed/34142343" target="_blank">34142343</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34063835">Diet and Nutrition in Gynecological Disorders: A Focus on Clinical Studies.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Afrin S,
AlAshqar A,
El Sabeh M,
Miyashita-Ishiwata M,
Reschke L,
Brennan JT,
Fader A,
Borahay MA</span><br />
<span class="medgenPMjournal">Nutrients</span>
2021 May 21;13(6)
doi: 10.3390/nu13061747.
<span class="bold">PMID: </span><a href="/pubmed/34063835" target="_blank">34063835</a><a href="/pmc/articles/PMC8224039" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25106763">Genomics of uterine leiomyomas: insights from high-throughput sequencing.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Mehine M,
Mäkinen N,
Heinonen HR,
Aaltonen LA,
Vahteristo P</span><br />
<span class="medgenPMjournal">Fertil Steril</span>
2014 Sep;102(3):621-9.
Epub 2014 Aug 5
doi: 10.1016/j.fertnstert.2014.06.050.
<span class="bold">PMID: </span><a href="/pubmed/25106763" target="_blank">25106763</a></div>
<div class="nl"><a target="_blank" href="/pubmed/12227898">Progestins and uterine leiomyoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Schweppe KW</span><br />
<span class="medgenPMjournal">Gynecol Endocrinol</span>
1999 Jun;13 Suppl 4:21-4.
doi: 10.1080/gye.13.s4.21.24.
<span class="bold">PMID: </span><a href="/pubmed/12227898" target="_blank">12227898</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Uterine%20leiomyoma%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (417)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/37576957">Genetic liability to multiple factors and uterine leiomyoma risk: a Mendelian randomization study.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Qu Y,
Chen L,
Guo S,
Liu Y,
Wu H</span><br />
<span class="medgenPMjournal">Front Endocrinol (Lausanne)</span>
2023;14:1133260.
Epub 2023 Jul 27
doi: 10.3389/fendo.2023.1133260.
<span class="bold">PMID: </span><a href="/pubmed/37576957" target="_blank">37576957</a><a href="/pmc/articles/PMC10415162" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36720535">Pyomyoma associated with bacteremia and puerperal pyrexia: A case report.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kenix Choi MC,
Chen LC,
Lee CC,
Tsai MS</span><br />
<span class="medgenPMjournal">Taiwan J Obstet Gynecol</span>
2023 Jan;62(1):171-174.
doi: 10.1016/j.tjog.2022.10.007.
<span class="bold">PMID: </span><a href="/pubmed/36720535" target="_blank">36720535</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25681841">Clinical management of leiomyoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Owen C,
Armstrong AY</span><br />
<span class="medgenPMjournal">Obstet Gynecol Clin North Am</span>
2015 Mar;42(1):67-85.
Epub 2014 Dec 5
doi: 10.1016/j.ogc.2014.09.009.
<span class="bold">PMID: </span><a href="/pubmed/25681841" target="_blank">25681841</a></div>
<div class="nl"><a target="_blank" href="/pubmed/24177458">Postnatal pyomyoma: a diagnostic dilemma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sirha R,
Miskin A,
Abdelmagied A</span><br />
<span class="medgenPMjournal">BMJ Case Rep</span>
2013 Oct 31;2013
doi: 10.1136/bcr-2013-201137.
<span class="bold">PMID: </span><a href="/pubmed/24177458" target="_blank">24177458</a><a href="/pmc/articles/PMC3822213" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/7746743">Peritoneal strumosis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Karseladze AI,
Kulinitch SI</span><br />
<span class="medgenPMjournal">Pathol Res Pract</span>
1994 Nov;190(11):1082-5; discussion 1086-8.
doi: 10.1016/S0344-0338(11)80905-2.
<span class="bold">PMID: </span><a href="/pubmed/7746743" target="_blank">7746743</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Uterine%20leiomyoma%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (320)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/37576957">Genetic liability to multiple factors and uterine leiomyoma risk: a Mendelian randomization study.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Qu Y,
Chen L,
Guo S,
Liu Y,
Wu H</span><br />
<span class="medgenPMjournal">Front Endocrinol (Lausanne)</span>
2023;14:1133260.
Epub 2023 Jul 27
doi: 10.3389/fendo.2023.1133260.
<span class="bold">PMID: </span><a href="/pubmed/37576957" target="_blank">37576957</a><a href="/pmc/articles/PMC10415162" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/36357960">Long-term Relugolix Combination Therapy for Symptomatic Uterine Leiomyomas.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Al-Hendy A,
Lukes AS,
Poindexter AN 3rd,
Venturella R,
Villarroel C,
McKain L,
Li Y,
Wagman RB,
Stewart EA</span><br />
<span class="medgenPMjournal">Obstet Gynecol</span>
2022 Dec 1;140(6):920-930.
Epub 2022 Nov 2
doi: 10.1097/AOG.0000000000004988.
<span class="bold">PMID: </span><a href="/pubmed/36357960" target="_blank">36357960</a><a href="/pmc/articles/PMC9665945" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34063835">Diet and Nutrition in Gynecological Disorders: A Focus on Clinical Studies.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Afrin S,
AlAshqar A,
El Sabeh M,
Miyashita-Ishiwata M,
Reschke L,
Brennan JT,
Fader A,
Borahay MA</span><br />
<span class="medgenPMjournal">Nutrients</span>
2021 May 21;13(6)
doi: 10.3390/nu13061747.
<span class="bold">PMID: </span><a href="/pubmed/34063835" target="_blank">34063835</a><a href="/pmc/articles/PMC8224039" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33569612">Uterine angiomyolipoma: a clinical analysis of 8 cases and literature review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wang J,
Yang Q,
Zhang N,
Wang D</span><br />
<span class="medgenPMjournal">Arch Gynecol Obstet</span>
2021 Jul;304(1):171-177.
Epub 2021 Feb 10
doi: 10.1007/s00404-021-05992-1.
<span class="bold">PMID: </span><a href="/pubmed/33569612" target="_blank">33569612</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27844480">The association between uterine leiomyoma and placenta abruption: A meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Jenabi E,
Ebrahimzadeh Zagami S</span><br />
<span class="medgenPMjournal">J Matern Fetal Neonatal Med</span>
2017 Nov;30(22):2742-2746.
Epub 2016 Nov 29
doi: 10.1080/14767058.2016.1261401.
<span class="bold">PMID: </span><a href="/pubmed/27844480" target="_blank">27844480</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Uterine%20leiomyoma%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (453)</a></div></div>
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<div class="nl"><a target="_blank" href="/pubmed/32795307">Correlation of low serum vitamin-D with uterine leiomyoma: a systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Mohammadi R,
Tabrizi R,
Hessami K,
Ashari H,
Nowrouzi-Sohrabi P,
Hosseini-Bensenjan M,
Asadi N</span><br />
<span class="medgenPMjournal">Reprod Biol Endocrinol</span>
2020 Aug 14;18(1):85.
doi: 10.1186/s12958-020-00644-6.
<span class="bold">PMID: </span><a href="/pubmed/32795307" target="_blank">32795307</a><a href="/pmc/articles/PMC7427296" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32474012">A systematic review of the psychosocial impact of fibroids before and after treatment.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Go VAA,
Thomas MC,
Singh B,
Prenatt S,
Sims H,
Blanck JF,
Segars JH</span><br />
<span class="medgenPMjournal">Am J Obstet Gynecol</span>
2020 Nov;223(5):674-708.e8.
Epub 2020 May 28
doi: 10.1016/j.ajog.2020.05.044.
<span class="bold">PMID: </span><a href="/pubmed/32474012" target="_blank">32474012</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27733017">Short-term and long-term effects of tibolone in postmenopausal women.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Formoso G,
Perrone E,
Maltoni S,
Balduzzi S,
Wilkinson J,
Basevi V,
Marata AM,
Magrini N,
D'Amico R,
Bassi C,
Maestri E</span><br />
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
2016 Oct 12;10(10):CD008536.
doi: 10.1002/14651858.CD008536.pub3.
<span class="bold">PMID: </span><a href="/pubmed/27733017" target="_blank">27733017</a><a href="/pmc/articles/PMC6458045" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/26838756">A systematic review on efficacy and safety of gasless laparoscopy in the management of uterine leiomyoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Liu QW,
Han T,
Yang M,
Tong XW,
Wang JJ</span><br />
<span class="medgenPMjournal">J Huazhong Univ Sci Technolog Med Sci</span>
2016 Feb;36(1):142-149.
Epub 2016 Feb 3
doi: 10.1007/s11596-016-1557-z.
<span class="bold">PMID: </span><a href="/pubmed/26838756" target="_blank">26838756</a></div>
<div class="nl"><a target="_blank" href="/pubmed/25609056">Presentation and treatment of uterine leiomyoma in adolescence: a systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Moroni RM,
Vieira CS,
Ferriani RA,
Reis RM,
Nogueira AA,
Brito LG</span><br />
<span class="medgenPMjournal">BMC Womens Health</span>
2015 Jan 22;15:4.
doi: 10.1186/s12905-015-0162-9.
<span class="bold">PMID: </span><a href="/pubmed/25609056" target="_blank">25609056</a><a href="/pmc/articles/PMC4308853" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Uterine%20leiomyoma%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (34)</a></div></div>
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<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0042133%5bDISCUI%5d&amp;filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (1)</a></li>
<li><a href="/gtr/tests?term=C0042133%5bDISCUI%5d&amp;filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (2)</a></li>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22uterine%20leiomyoma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Uterine%20leiomyoma%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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<div class="portlet_content ln"><ul><li><a href="https://catalog.coriell.org/Search?q=150699" target="_blank">Coriell Institute for Medical Research</a></li></ul></div>
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<div class="portlet_content ln"><ul><li><a href="https://www.malacards.org/card/leiomyoma_uterine" target="_blank">MalaCards</a></li><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&amp;query=Uterine%20leiomyoma" target="_blank">MedlinePlus</a></li></ul></div>
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