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<!--
|
||
UID=20772
|
||
ConceptID=C0037199
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Sinusitis</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>20772</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0037199</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Infection, Sinus; Infections, Sinus; Sinus Infection; Sinus Infections; Sinusitides</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Sinusitis (36971009)</td></tr>
|
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<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0000246">HP:0000246</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0005961" target="_blank">MONDO:0005961</a></td></tr>
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</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">Inflammation of the paranasal sinuses owing to a viral, bacterial, or fungal infection, allergy, or an autoimmune reaction. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0037199[DISCUI]&test_type=Clinical" ref="ncbi_uid=20772">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Sinusitis</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/19750" ref="tree=MeSH" title="MedGen record for Disease, Respiratory Tract">Disease, Respiratory Tract</a></span><ul><li><span class="TLline"><a href="/medgen/10385" ref="tree=MeSH" title="MedGen record for Nasal disorder">Nasal disorder</a></span><ul><li><span class="TLline"><a href="/medgen/14608" ref="tree=MeSH" title="MedGen record for Disorder of nasal sinus">Disorder of nasal sinus</a></span><ul><li><span class="matched_ds">Sinusitis</span><ul><li><span class="TLline"><a href="/medgen/56188" ref="tree=MeSH" title="MedGen record for Acute sinusitis">Acute sinusitis</a></span></li><li><span class="TLline"><a href="/medgen/101751" ref="tree=MeSH" title="MedGen record for Chronic sinusitis">Chronic sinusitis</a></span><ul><li><span class="TLline"><a href="/medgen/3454" ref="tree=MeSH" title="MedGen record for Chronic ethmoidal sinusitis">Chronic ethmoidal sinusitis</a></span></li><li><span class="TLline"><a href="/medgen/3455" ref="tree=MeSH" title="MedGen record for Chronic frontal sinusitis">Chronic frontal sinusitis</a></span></li><li><span class="TLline"><a href="/medgen/966" ref="tree=MeSH" title="MedGen record for Chronic maxillary sinusitis">Chronic maxillary sinusitis</a></span></li><li><span class="TLline"><a href="/medgen/3087" ref="tree=MeSH" title="MedGen record for Chronic sphenoidal sinusitis">Chronic sphenoidal sinusitis</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/5046" ref="tree=MeSH" title="MedGen record for Ethmoid sinusitis">Ethmoid sinusitis</a></span></li><li><span class="TLline"><a href="/medgen/8919" ref="tree=MeSH" title="MedGen record for Frontal sinusitis">Frontal sinusitis</a></span></li><li><span class="TLline"><a href="/medgen/44313" ref="tree=MeSH" title="MedGen record for Maxillary sinusitis">Maxillary sinusitis</a></span></li><li><span class="TLline"><a href="/medgen/923118" ref="tree=MeSH" title="MedGen record for Rhinosinusitis">Rhinosinusitis</a></span></li><li><span class="TLline"><a href="/medgen/11543" ref="tree=MeSH" title="MedGen record for Sphenoid sinusitis">Sphenoid sinusitis</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_439"><div><strong>Ataxia-telangiectasia syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>439</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0004135</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The phenotypic spectrum of ataxia-telangiectasia (A-T), a multisystem disorder, is a continuum ranging from classic A-T at the severe end and variant A-T at the milder end. Nonetheless, distinguishing between classic A-T and variant A-T on this spectrum helps understand differences in disease course, rate of progression, and life expectancy. Classic A-T is characterized by childhood onset of progressive neurologic manifestations (initially cerebellar ataxia, followed typically by extrapyramidal involvement and peripheral sensorimotor neuropathy), immunodeficiency (variably associated with abnormalities of humoral immunity, cellular immunity, or combined immune deficiency), pulmonary disease (resulting from recurrent infections, immune deficiency, aspiration, interstitial lung disease, and neurologic abnormalities), and increased risk of malignancy. Although it is generally accepted that intellectual disability is not common in A-T, disturbances in cerebellar as well as non-cerebellar brain areas and networks may result in cognitive deficits. Increased sensitivity to ionizing radiation (x-ray and gamma ray) can result in severe side effects from such treatments. Life expectancy is significantly reduced due to cancer, pulmonary disease, and infections. Variant A-T has a significantly milder disease course. While cerebellar ataxia can be absent, extrapyramidal movement disorders are common (typically dystonia and dystonic tremor) and most individuals have manifestations of axonal sensorimotor polyneuropathy. In contrast to classic A-T, immune function is generally normal, respiratory infections are not increased, and pulmonary disease is not a major feature. However, risk of developing malignancies is increased, particularly in premenopausal females who have an increased risk of developing breast cancer and hematologic malignancies.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/439">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_75653"><div><strong>Purine-nucleoside phosphorylase deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>75653</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0268125</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Purine nucleoside phosphorylase deficiency is a rare autosomal recessive immunodeficiency disorder characterized mainly by decreased T-cell function. Some patients also have neurologic impairment (review by Aust et al., 1992).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/75653">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_137933"><div><strong>Immotile cilia syndrome due to defective radial spokes</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>137933</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0340035</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/137933">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_140771"><div><strong>Microcephaly, normal intelligence and immunodeficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>140771</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0398791</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Nijmegen breakage syndrome (NBS) is characterized by progressive microcephaly, early growth deficiency that improves with age, recurrent respiratory infections, an increased risk for malignancy (primarily lymphoma), and premature ovarian failure in females. Developmental milestones are attained at the usual time during the first year; however, borderline delays in development and hyperactivity may be observed in early childhood. Intellectual abilities tend to decline over time. Recurrent pneumonia and bronchitis may result in respiratory failure and early death. Other reported malignancies include solid tumors (e.g., medulloblastoma, glioma, rhabdomyosarcoma).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/140771">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_141630"><div><strong>X-linked agammaglobulinemia with growth hormone deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>141630</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0472813</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">IGHD3 is characterized by agammaglobulinemia and markedly reduced numbers of B cells, short stature, delayed bone age, and good response to treatment with growth hormone (summary by Conley et al., 1991). For general phenotypic information and a discussion of genetic heterogeneity of IGHD, see 262400.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/141630">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_220906"><div><strong>X-linked severe combined immunodeficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>220906</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1279481</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The phenotypic spectrum of X-linked severe combined immunodeficiency (X-SCID) ranges from typical X-SCID (early-onset disease in males that is fatal if not treated with hematopoietic stem cell transplantation [HSCT] or gene therapy) to atypical X-SCID (later-onset disease comprising phenotypes caused by variable immunodeficiency, immune dysregulation, and/or autoimmunity). Typical X-SCID. Prior to universal newborn screening (NBS) for SCID most males with typical X-SCID came to medical attention between ages three and six months because of recurrent infections, persistent infections, and infections with opportunistic organisms. With universal NBS for SCID, the common presentation for typical X-SCID is now an asymptomatic, healthy-appearing male infant. Atypical X-SCID, which usually is not detected by NBS, can manifest in the first years of life or later with one of the following: recurrent upper and lower respiratory tract infections with bronchiectasis; Omenn syndrome, a clinical phenotype caused by immune dysregulation; X-SCID combined immunodeficiency (often with recurrent infections, warts, and dermatitis); immune dysregulation and autoimmunity; or Epstein-Barr virus-related lymphoproliferative complications.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/220906">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_332018"><div><strong>Familial congenital nasolacrimal duct obstruction</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>332018</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1835612</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
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||
<div class="spaceAbove">Congenital nasolacrimal drainage system impatency is relatively common, occurring in approximately 20% of children within the first year of life. Such infants typically manifest persistent epiphora and/or recurrent infections of the lacrimal pathway such as conjunctivitis. The most frequent site of such obstruction occurs at the distal intranasal segment of the nasolacrimal drainage system at the valve of Hasner (summary by Wang and Cunningham, 2011). Congenital dacryocystocele, an uncommon variant of nasolacrimal duct obstruction, characterized by the appearance of a cystic blue mass over the area of the lacrimal duct soon after birth. Dacryocystoceles are thought to result from a persistent membrane at the valve of Hasner and a functional obstruction of the common canaliculus or valve of Rosenmuller. The resulting lacrimal sac distention has been reported to be more common in female and non-Hispanic white patients, and familial cases have been described only sporadically. Common presenting signs include dacryocystitis, facial cellulitis, and respiratory distress; the development of astigmatism in association with dacryocystocele has only rarely been observed (summary by Shekunov et al., 2010).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/332018">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_338258"><div><strong>Primary ciliary dyskinesia 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>338258</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1847554</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Primary ciliary dyskinesia-2 (CILD2) is an autosomal recessive disorder arising from immotile cilia that lack both outer and inner dynein arms. Ineffective airway mucociliary clearance usually manifests within the first year of life with recurrent infections resulting in a chronic respiratory condition and progressing to permanent lung damage. Some patients have nasal polyps, infertility, or hearing loss. About half of patients have situs inversus (Mitchison et al., 2012). For a phenotypic description and a discussion of genetic heterogeneity of primary ciliary dyskinesia, see 244400.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/338258">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_383722"><div><strong>Keutel syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>383722</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1855607</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Keutel syndrome (KTLS) is an autosomal recessive disorder characterized by multiple peripheral pulmonary stenoses, brachytelephalangy, inner ear deafness, and abnormal cartilage ossification or calcification (summary by Khosroshahi et al., 2014).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/383722">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_354935"><div><strong>Severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-negative, due to adenosine deaminase deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>354935</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C1863236</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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||
<div class="spaceAbove">Adenosine deaminase (ADA) deficiency is a systemic purine metabolic disorder that primarily affects lymphocyte development, viability, and function. The ADA deficiency phenotypic spectrum includes typical early-onset severe combined immunodeficiency (ADA-SCID), diagnosed in infancy (about 80% of individuals), and less severe "delayed" or "late-onset" combined immunodeficiency (ADA-CID), diagnosed in older children and adults (15%-20% of individuals). Some healthy individuals who are deficient in red blood cell ADA (termed "partial ADA deficiency") have been discovered by screening populations or relatives of individuals with ADA-SCID. Newborn screening (NBS) for SCID uses extracts from Guthrie card dried blood spots to measure T-cell receptor excision circle (TREC) DNA by polymerase chain reaction (PCR). Screening specific for ADA deficiency can also be performed by detection of elevated levels of adenosine (Ado) and deoxyadenosine (dAdo) by tandem mass spectrometry (TMS). Both techniques can identify ADA-SCID before affected infants become symptomatic. Untreated ADA-SCID presents as life-threatening opportunistic illnesses in the first weeks to months of life with poor linear growth and weight gain secondary to persistent diarrhea, extensive dermatitis, and recurrent pneumonia. Skeletal abnormalities affecting ribs and vertebra, pulmonary alveolar proteinosis, hemolytic anemia, neurologic abnormalities, and transaminitis may also suggest untreated ADA-SCID. Characteristic immune abnormalities are lymphocytopenia (low numbers of T, B, and NK cells) combined with the absence of both humoral and cellular immune function. If immune function is not restored with enzyme replacement therapy (ERT), gene therapy, or hematopoietic stem cell transplantation (HSCT), children with ADA-SCID rarely survive beyond age one to two years. NBS for SCID does not identify individuals with the ADA-CID phenotype whose TREC numbers are above the threshold values of most screening laboratories. However, ADA-CID is identified by TMS NBS since the ADA substrates Ado and dAdo are increased. As TMS NBS for Ado/dAdo is not yet widely performed, individuals with ADA-CID are more often clinically diagnosed between ages one and ten years ("delayed" onset), or less often in the second to fourth decades ("late"/"adult" onset). Because the immunologic abnormalities are less pronounced than those of ADA-SCID, infections in ADA-CID may not be life-threatening and include recurrent otitis media, sinusitis, upper respiratory infections, and human papilloma viral infections. Untreated individuals with ADA-CID can develop over time chronic pulmonary disease, autoimmunity, atopic disease with elevated immunoglobulin E, and malignancy.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/354935">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_370930"><div><strong>Primary ciliary dyskinesia 6</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>370930</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1970506</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
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||
<div class="spaceAbove">Rarely, individuals with primary ciliary dyskinesia have an accumulation of fluid in the brain (hydrocephalus), likely due to abnormal cilia in the brain.\n\nAnother feature of primary ciliary dyskinesia is recurrent ear infections (otitis media), especially in young children. Otitis media can lead to permanent hearing loss if untreated. The ear infections are likely related to abnormal cilia within the inner ear.\n\nPrimary ciliary dyskinesia can also lead to infertility. Vigorous movements of the flagella are necessary to propel the sperm cells forward to the female egg cell. Because their sperm do not move properly, males with primary ciliary dyskinesia are usually unable to father children. Infertility occurs in some affected females and is likely due to abnormal cilia in the fallopian tubes.\n\nApproximately 12 percent of people with primary ciliary dyskinesia have a condition known as heterotaxy syndrome or situs ambiguus, which is characterized by abnormalities of the heart, liver, intestines, or spleen. These organs may be structurally abnormal or improperly positioned. In addition, affected individuals may lack a spleen (asplenia) or have multiple spleens (polysplenia). Heterotaxy syndrome results from problems establishing the left and right sides of the body during embryonic development. The severity of heterotaxy varies widely among affected individuals.\n\nSome individuals with primary ciliary dyskinesia have abnormally placed organs within their chest and abdomen. These abnormalities arise early in embryonic development when the differences between the left and right sides of the body are established. About 50 percent of people with primary ciliary dyskinesia have a mirror-image reversal of their internal organs (situs inversus totalis). For example, in these individuals the heart is on the right side of the body instead of on the left. Situs inversus totalis does not cause any apparent health problems. When someone with primary ciliary dyskinesia has situs inversus totalis, they are often said to have Kartagener syndrome.\n\nIn the respiratory tract, cilia move back and forth in a coordinated way to move mucus towards the throat. This movement of mucus helps to eliminate fluid, bacteria, and particles from the lungs. Most babies with primary ciliary dyskinesia experience breathing problems at birth, which suggests that cilia play an important role in clearing fetal fluid from the lungs. Beginning in early childhood, affected individuals develop frequent respiratory tract infections. Without properly functioning cilia in the airway, bacteria remain in the respiratory tract and cause infection. People with primary ciliary dyskinesia also have year-round nasal congestion and a chronic cough. Chronic respiratory tract infections can result in a condition called bronchiectasis, which damages the passages, called bronchi, leading from the windpipe to the lungs and can cause life-threatening breathing problems.\n\nPrimary ciliary dyskinesia is a disorder characterized by chronic respiratory tract infections, abnormally positioned internal organs, and the inability to have children (infertility). The signs and symptoms of this condition are caused by abnormal cilia and flagella. Cilia are microscopic, finger-like projections that stick out from the surface of cells. They are found in the linings of the airway, the reproductive system, and other organs and tissues. Flagella are tail-like structures, similar to cilia, that propel sperm cells forward.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/370930">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_811223"><div><strong>Granulomatosis with polyangiitis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>811223</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3495801</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Granulomatosis with polyangiitis, formerly termed Wegener granulomatosis, is a systemic disease with a complex genetic background. It is characterized by necrotizing granulomatous inflammation of the upper and lower respiratory tract, glomerulonephritis, vasculitis, and the presence of antineutrophil cytoplasmatic autoantibodies (ANCAs) in patient sera. These ANCAs are antibodies to a defined target antigen, proteinase-3 (PR3, PRTN3; 177020), which is present within primary azurophil granules of neutrophils (PMNs) and lysozymes of monocytes. On cytokine priming of PMNs, PR3 translocates to the cell surface, where PR3-ANCAs can interact with their antigens and activate PMNs. PMNs from patients with active GPA express PR3 on their surface, produce respiratory burst, and release proteolytic enzymes after activation with PR3-ANCAs. The consequence is a self-sustaining inflammatory process (Jagiello et al., 2004).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/811223">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_865178"><div><strong>Immunodeficiency 32B</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>865178</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4016741</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Immunodeficiency-32B is an autosomal recessive primary immunodeficiency characterized by recurrent infections resulting from variable defects in immune cell development or function, including monocytes, dendritic cells, and natural killer (NK) cells. Patients have particular susceptibility to viral disease (summary by Mace et al., 2017).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/865178">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1636193"><div><strong>Immunodeficiency-centromeric instability-facial anomalies syndrome 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1636193</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4551557</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Immunodeficiency, centromeric instability, and facial dysmorphism (ICF) syndrome is a rare autosomal recessive disease characterized by facial dysmorphism, immunoglobulin deficiency, and branching of chromosomes 1, 9, and 16 after phytohemagglutinin (PHA) stimulation of lymphocytes. Hypomethylation of DNA of a small fraction of the genome is an unusual feature of ICF patients that is explained by mutations in the DNMT3B gene in some, but not all, ICF patients (Hagleitner et al., 2008). Genetic Heterogeneity of Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome See also ICF2 (614069), caused by mutation in the ZBTB24 gene (614064) on chromosome 6q21; ICF3 (616910), caused by mutation in the CDCA7 gene (609937) on chromosome 2q31; and ICF4 (616911), caused by mutation in the HELLS gene (603946) on chromosome 10q23.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1636193">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1648456"><div><strong>Proteasome-associated autoinflammatory syndrome 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1648456</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4747850</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Proteasome-associated autoinflammatory syndrome-3 (PRAAS3) is an autosomal recessive syndrome with onset in early infancy. Affected individuals present with nodular dermatitis, recurrent fever, myositis, panniculitis-induced lipodystrophy, lymphadenopathy, and dysregulation of the immune response, particularly associated with abnormal type I interferon-induced gene expression patterns. Additional features are highly variable, but may include joint contractures, hepatosplenomegaly, anemia, thrombocytopenia, recurrent infections, autoantibodies, and hypergammaglobulinemia. Some patients may have intracranial calcifications (summary by Brehm et al., 2015). For a discussion of genetic heterogeneity of PRAAS, see PRAAS1 (256040).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1648456">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1848763"><div><strong>Immunodeficiency 117</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1848763</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5882739</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Immunodeficiency-117 (IMD117) is an autosomal recessive immunologic disorder characterized by increased susceptibility to disseminated mycobacterial infection apparent in early childhood. Affected individuals develop mycobacterial disease after BCG (bacille Calmette-Guerin) vaccination and show increased susceptibility to other mycobacterial infections, such as M. avium. Immunologic workup shows impaired development of myeloid and lymphoid cell subsets that secrete and respond to gamma-interferon (IFNG; 147570) (et al., 2023).</div>
|
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<div class="spaceAbove nowrap">See: <a href="/medgen/1848763">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_439" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Ataxia-telangiectasia syndrome</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_332018" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial congenital nasolacrimal duct obstruction</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_811223" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Granulomatosis with polyangiitis</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_137933" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Immotile cilia syndrome due to defective radial spokes</a></div>
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||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1848763" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Immunodeficiency 117</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (16)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_865178" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Immunodeficiency 32B</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1636193" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Immunodeficiency-centromeric instability-facial anomalies syndrome 1</a></div>
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||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_383722" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Keutel syndrome</a></div>
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||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_140771" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Microcephaly, normal intelligence and immunodeficiency</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_338258" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Primary ciliary dyskinesia 2</a></div>
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||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_370930" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Primary ciliary dyskinesia 6</a></div>
|
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1648456" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Proteasome-associated autoinflammatory syndrome 3</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_75653" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Purine-nucleoside phosphorylase deficiency</a></div>
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||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_354935" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-negative, due to adenosine deaminase deficiency</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_141630" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">X-linked agammaglobulinemia with growth hormone deficiency</a></div>
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<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_220906" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">X-linked severe combined immunodeficiency</a></div></span></div></div>
|
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</div>
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<div class="portlet mgSection" id="ID_105">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
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<div class="nl"><a target="_blank" href="/pubmed/36878860">International consensus statement on allergy and rhinology: Allergic rhinitis - 2023.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Wise SK,
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Damask C,
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Roland LT,
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Ebert C,
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Levy JM,
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Lin S,
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Luong A,
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Rodriguez K,
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Sedaghat AR,
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Toskala E,
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Villwock J,
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Abdullah B,
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Akdis C,
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Alt JA,
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Ansotegui IJ,
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Azar A,
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Baroody F,
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Benninger MS,
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Bernstein J,
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Brook C,
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Campbell R,
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Casale T,
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Chaaban MR,
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Chew FT,
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Chambliss J,
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Cianferoni A,
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Custovic A,
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Davis EM,
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DelGaudio JM,
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Ellis AK,
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Flanagan C,
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Fokkens WJ,
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Franzese C,
|
||
Greenhawt M,
|
||
Gill A,
|
||
Halderman A,
|
||
Hohlfeld JM,
|
||
Incorvaia C,
|
||
Joe SA,
|
||
Joshi S,
|
||
Kuruvilla ME,
|
||
Kim J,
|
||
Klein AM,
|
||
Krouse HJ,
|
||
Kuan EC,
|
||
Lang D,
|
||
Larenas-Linnemann D,
|
||
Laury AM,
|
||
Lechner M,
|
||
Lee SE,
|
||
Lee VS,
|
||
Loftus P,
|
||
Marcus S,
|
||
Marzouk H,
|
||
Mattos J,
|
||
McCoul E,
|
||
Melen E,
|
||
Mims JW,
|
||
Mullol J,
|
||
Nayak JV,
|
||
Oppenheimer J,
|
||
Orlandi RR,
|
||
Phillips K,
|
||
Platt M,
|
||
Ramanathan M Jr,
|
||
Raymond M,
|
||
Rhee CS,
|
||
Reitsma S,
|
||
Ryan M,
|
||
Sastre J,
|
||
Schlosser RJ,
|
||
Schuman TA,
|
||
Shaker MS,
|
||
Sheikh A,
|
||
Smith KA,
|
||
Soyka MB,
|
||
Takashima M,
|
||
Tang M,
|
||
Tantilipikorn P,
|
||
Taw MB,
|
||
Tversky J,
|
||
Tyler MA,
|
||
Veling MC,
|
||
Wallace D,
|
||
Wang Y,
|
||
White A,
|
||
Zhang L</span><br />
|
||
<span class="medgenPMjournal">Int Forum Allergy Rhinol</span>
|
||
2023 Apr;13(4):293-859.
|
||
Epub 2023 Mar 6
|
||
doi: 10.1002/alr.23090.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36878860" target="_blank">36878860</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35243888">Allergic rhinitis: diagnosis and management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Siddiqui ZA,
|
||
Walker A,
|
||
Pirwani MM,
|
||
Tahiri M,
|
||
Syed I</span><br />
|
||
<span class="medgenPMjournal">Br J Hosp Med (Lond)</span>
|
||
2022 Feb 2;83(2):1-9.
|
||
Epub 2022 Feb 23
|
||
doi: 10.12968/hmed.2021.0570.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35243888" target="_blank">35243888</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25832968">Clinical practice guideline (update): adult sinusitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rosenfeld RM,
|
||
Piccirillo JF,
|
||
Chandrasekhar SS,
|
||
Brook I,
|
||
Ashok Kumar K,
|
||
Kramper M,
|
||
Orlandi RR,
|
||
Palmer JN,
|
||
Patel ZM,
|
||
Peters A,
|
||
Walsh SA,
|
||
Corrigan MD</span><br />
|
||
<span class="medgenPMjournal">Otolaryngol Head Neck Surg</span>
|
||
2015 Apr;152(2 Suppl):S1-S39.
|
||
doi: 10.1177/0194599815572097.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25832968" target="_blank">25832968</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22sinusitis%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (1108)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35477843">Novel Devices for Sinus Headache.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Miglani A,
|
||
Soler Z,
|
||
Schlosser RJ</span><br />
|
||
<span class="medgenPMjournal">Otolaryngol Clin North Am</span>
|
||
2022 Jun;55(3):519-529.
|
||
Epub 2022 Apr 25
|
||
doi: 10.1016/j.otc.2022.02.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35477843" target="_blank">35477843</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33122642">Adult chronic rhinosinusitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMjournal">Nat Rev Dis Primers</span>
|
||
2020 Oct 29;6(1):87.
|
||
doi: 10.1038/s41572-020-00229-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33122642" target="_blank">33122642</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26749201">EDITORIAL.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kern RC</span><br />
|
||
<span class="medgenPMjournal">Int Forum Allergy Rhinol</span>
|
||
2016 Jan;6(1):5-7.
|
||
doi: 10.1002/alr.21713.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26749201" target="_blank">26749201</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21047024">Acute sinusitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mehrtens JM,
|
||
Spigarelli MG</span><br />
|
||
<span class="medgenPMjournal">Adolesc Med State Art Rev</span>
|
||
2010 Aug;21(2):187-201, vii.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21047024" target="_blank">21047024</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18589842">Occupational rhinosinusitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hellgren J</span><br />
|
||
<span class="medgenPMjournal">Curr Allergy Asthma Rep</span>
|
||
2008 May;8(3):234-9.
|
||
doi: 10.1007/s11882-008-0039-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18589842" target="_blank">18589842</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Sinusitis%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (8954)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/30454779">Sinusitis Update.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wyler B,
|
||
Mallon WK</span><br />
|
||
<span class="medgenPMjournal">Emerg Med Clin North Am</span>
|
||
2019 Feb;37(1):41-54.
|
||
doi: 10.1016/j.emc.2018.09.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30454779" target="_blank">30454779</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27622225">Sinusitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Morcom S,
|
||
Phillips N,
|
||
Pastuszek A,
|
||
Timperley D</span><br />
|
||
<span class="medgenPMjournal">Aust Fam Physician</span>
|
||
2016 Jun;45(6):374-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27622225" target="_blank">27622225</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26476380">Fungal Sinusitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Raz E,
|
||
Win W,
|
||
Hagiwara M,
|
||
Lui YW,
|
||
Cohen B,
|
||
Fatterpekar GM</span><br />
|
||
<span class="medgenPMjournal">Neuroimaging Clin N Am</span>
|
||
2015 Nov;25(4):569-76.
|
||
Epub 2015 Aug 21
|
||
doi: 10.1016/j.nic.2015.07.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26476380" target="_blank">26476380</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21047024">Acute sinusitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mehrtens JM,
|
||
Spigarelli MG</span><br />
|
||
<span class="medgenPMjournal">Adolesc Med State Art Rev</span>
|
||
2010 Aug;21(2):187-201, vii.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21047024" target="_blank">21047024</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2035989">Sinusitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Friedman RA,
|
||
Harris JP</span><br />
|
||
<span class="medgenPMjournal">Annu Rev Med</span>
|
||
1991;42:471-89.
|
||
doi: 10.1146/annurev.me.42.020191.002351.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2035989" target="_blank">2035989</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Sinusitis%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (9244)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/30851191">Conjunctivitis in dupilumab clinical trials.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Akinlade B,
|
||
Guttman-Yassky E,
|
||
de Bruin-Weller M,
|
||
Simpson EL,
|
||
Blauvelt A,
|
||
Cork MJ,
|
||
Prens E,
|
||
Asbell P,
|
||
Akpek E,
|
||
Corren J,
|
||
Bachert C,
|
||
Hirano I,
|
||
Weyne J,
|
||
Korotzer A,
|
||
Chen Z,
|
||
Hultsch T,
|
||
Zhu X,
|
||
Davis JD,
|
||
Mannent L,
|
||
Hamilton JD,
|
||
Teper A,
|
||
Staudinger H,
|
||
Rizova E,
|
||
Pirozzi G,
|
||
Graham NMH,
|
||
Shumel B,
|
||
Ardeleanu M,
|
||
Wollenberg A</span><br />
|
||
<span class="medgenPMjournal">Br J Dermatol</span>
|
||
2019 Sep;181(3):459-473.
|
||
Epub 2019 May 7
|
||
doi: 10.1111/bjd.17869.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30851191" target="_blank">30851191</a><a href="/pmc/articles/PMC6850316" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30198548">Antibiotics for acute rhinosinusitis in adults.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lemiengre MB,
|
||
van Driel ML,
|
||
Merenstein D,
|
||
Liira H,
|
||
Mäkelä M,
|
||
De Sutter AI</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2018 Sep 10;9(9):CD006089.
|
||
doi: 10.1002/14651858.CD006089.pub5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30198548" target="_blank">30198548</a><a href="/pmc/articles/PMC6513448" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29562756">Whither Sinusitis?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Weinberger M</span><br />
|
||
<span class="medgenPMjournal">Clin Pediatr (Phila)</span>
|
||
2018 Aug;57(9):1013-1019.
|
||
Epub 2018 Mar 22
|
||
doi: 10.1177/0009922818764927.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29562756" target="_blank">29562756</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26314824">For the Patient.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bellanti JA,
|
||
Settipane RA</span><br />
|
||
<span class="medgenPMjournal">Allergy Asthma Proc</span>
|
||
2015 Sep-Oct;36(5):412.
|
||
doi: 10.2500/aap.2015.36.3894.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26314824" target="_blank">26314824</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/15202731">Talniflumate (Genaera).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Knight D</span><br />
|
||
<span class="medgenPMjournal">Curr Opin Investig Drugs</span>
|
||
2004 May;5(5):557-62.
|
||
<span class="bold">PMID: </span><a href="/pubmed/15202731" target="_blank">15202731</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Sinusitis%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (7787)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/33122665">Adult chronic rhinosinusitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bachert C,
|
||
Marple B,
|
||
Schlosser RJ,
|
||
Hopkins C,
|
||
Schleimer RP,
|
||
Lambrecht BN,
|
||
Bröker BM,
|
||
Laidlaw T,
|
||
Song WJ</span><br />
|
||
<span class="medgenPMjournal">Nat Rev Dis Primers</span>
|
||
2020 Oct 29;6(1):86.
|
||
doi: 10.1038/s41572-020-00218-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33122665" target="_blank">33122665</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33122642">Adult chronic rhinosinusitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMjournal">Nat Rev Dis Primers</span>
|
||
2020 Oct 29;6(1):87.
|
||
doi: 10.1038/s41572-020-00229-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33122642" target="_blank">33122642</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29562756">Whither Sinusitis?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Weinberger M</span><br />
|
||
<span class="medgenPMjournal">Clin Pediatr (Phila)</span>
|
||
2018 Aug;57(9):1013-1019.
|
||
Epub 2018 Mar 22
|
||
doi: 10.1177/0009922818764927.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29562756" target="_blank">29562756</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21358193">Chronic rhinosinusitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang X,
|
||
Cutting GR</span><br />
|
||
<span class="medgenPMjournal">Adv Otorhinolaryngol</span>
|
||
2011;70:114-121.
|
||
Epub 2011 Feb 24
|
||
doi: 10.1159/000322487.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21358193" target="_blank">21358193</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7848639">Endoscopic sinus surgery.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Maran AG</span><br />
|
||
<span class="medgenPMjournal">Eur Arch Otorhinolaryngol</span>
|
||
1994;251(6):309-18.
|
||
doi: 10.1007/BF00171536.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7848639" target="_blank">7848639</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Sinusitis%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4262)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39149992">Comparative Effectiveness of Dupilumab Versus Sinus Surgery for Chronic Rhinosinusitis With Polyps: Systematic Review and a Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kim DH,
|
||
Stybayeva G,
|
||
Hwang SH</span><br />
|
||
<span class="medgenPMjournal">Am J Rhinol Allergy</span>
|
||
2024 Nov;38(6):428-436.
|
||
Epub 2024 Aug 16
|
||
doi: 10.1177/19458924241272978.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39149992" target="_blank">39149992</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37987873">Type 2 Biomarkers for the Indication and Response to Biologics in CRSwNP.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Guo CL,
|
||
Liu FF,
|
||
Wang DY,
|
||
Liu Z</span><br />
|
||
<span class="medgenPMjournal">Curr Allergy Asthma Rep</span>
|
||
2023 Dec;23(12):703-713.
|
||
Epub 2023 Nov 21
|
||
doi: 10.1007/s11882-023-01114-w.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37987873" target="_blank">37987873</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26836729">Effect of Subcutaneous Dupilumab on Nasal Polyp Burden in Patients With Chronic Sinusitis and Nasal Polyposis: A Randomized Clinical Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bachert C,
|
||
Mannent L,
|
||
Naclerio RM,
|
||
Mullol J,
|
||
Ferguson BJ,
|
||
Gevaert P,
|
||
Hellings P,
|
||
Jiao L,
|
||
Wang L,
|
||
Evans RR,
|
||
Pirozzi G,
|
||
Graham NM,
|
||
Swanson B,
|
||
Hamilton JD,
|
||
Radin A,
|
||
Gandhi NA,
|
||
Stahl N,
|
||
Yancopoulos GD,
|
||
Sutherland ER</span><br />
|
||
<span class="medgenPMjournal">JAMA</span>
|
||
2016 Feb 2;315(5):469-79.
|
||
doi: 10.1001/jama.2015.19330.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26836729" target="_blank">26836729</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25945591">Novel scoring system and algorithm for classifying chronic rhinosinusitis: the JESREC Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tokunaga T,
|
||
Sakashita M,
|
||
Haruna T,
|
||
Asaka D,
|
||
Takeno S,
|
||
Ikeda H,
|
||
Nakayama T,
|
||
Seki N,
|
||
Ito S,
|
||
Murata J,
|
||
Sakuma Y,
|
||
Yoshida N,
|
||
Terada T,
|
||
Morikura I,
|
||
Sakaida H,
|
||
Kondo K,
|
||
Teraguchi K,
|
||
Okano M,
|
||
Otori N,
|
||
Yoshikawa M,
|
||
Hirakawa K,
|
||
Haruna S,
|
||
Himi T,
|
||
Ikeda K,
|
||
Ishitoya J,
|
||
Iino Y,
|
||
Kawata R,
|
||
Kawauchi H,
|
||
Kobayashi M,
|
||
Yamasoba T,
|
||
Miwa T,
|
||
Urashima M,
|
||
Tamari M,
|
||
Noguchi E,
|
||
Ninomiya T,
|
||
Imoto Y,
|
||
Morikawa T,
|
||
Tomita K,
|
||
Takabayashi T,
|
||
Fujieda S</span><br />
|
||
<span class="medgenPMjournal">Allergy</span>
|
||
2015 Aug;70(8):995-1003.
|
||
Epub 2015 May 26
|
||
doi: 10.1111/all.12644.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25945591" target="_blank">25945591</a><a href="/pmc/articles/PMC5032997" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17767604">Exhaled nitric oxide in children with asthma and sinusitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Carraro S,
|
||
Gottardi G,
|
||
Bonetto G,
|
||
Baraldi E</span><br />
|
||
<span class="medgenPMjournal">Pediatr Allergy Immunol</span>
|
||
2007 Nov;18 Suppl 18:28-30.
|
||
doi: 10.1111/j.1399-3038.2007.00629.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17767604" target="_blank">17767604</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Sinusitis%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5379)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/37157782">Efficacy and safety of bromelain: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Leelakanok N,
|
||
Petchsomrit A,
|
||
Janurai T,
|
||
Saechan C,
|
||
Sunsandee N</span><br />
|
||
<span class="medgenPMjournal">Nutr Health</span>
|
||
2023 Sep;29(3):479-503.
|
||
Epub 2023 May 8
|
||
doi: 10.1177/02601060231173732.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37157782" target="_blank">37157782</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36305427">Progression of noninvasive fungal sinusitis to invasive fungal sinusitis: A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Goyal SS,
|
||
Doering M,
|
||
Kendall PL,
|
||
Farrell N,
|
||
Schneider JS,
|
||
Roland LT</span><br />
|
||
<span class="medgenPMjournal">Int Forum Allergy Rhinol</span>
|
||
2023 Jun;13(6):1024-1033.
|
||
Epub 2022 Nov 8
|
||
doi: 10.1002/alr.23097.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36305427" target="_blank">36305427</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31973547">TNF-Alpha Inhibitors and Rhinosinusitis-A Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Piski Z,
|
||
Gerlinger I,
|
||
Nepp N,
|
||
Farkas K,
|
||
Weber R</span><br />
|
||
<span class="medgenPMjournal">Am J Rhinol Allergy</span>
|
||
2020 May;34(3):436-442.
|
||
Epub 2020 Jan 23
|
||
doi: 10.1177/1945892419898988.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31973547" target="_blank">31973547</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30198548">Antibiotics for acute rhinosinusitis in adults.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lemiengre MB,
|
||
van Driel ML,
|
||
Merenstein D,
|
||
Liira H,
|
||
Mäkelä M,
|
||
De Sutter AI</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2018 Sep 10;9(9):CD006089.
|
||
doi: 10.1002/14651858.CD006089.pub5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30198548" target="_blank">30198548</a><a href="/pmc/articles/PMC6513448" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29859573">Management of pediatric orbital cellulitis: A systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wong SJ,
|
||
Levi J</span><br />
|
||
<span class="medgenPMjournal">Int J Pediatr Otorhinolaryngol</span>
|
||
2018 Jul;110:123-129.
|
||
Epub 2018 May 8
|
||
doi: 10.1016/j.ijporl.2018.05.006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29859573" target="_blank">29859573</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Sinusitis%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (505)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
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||
|
||
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|
||
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|
||
|
||
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|
||
|
||
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|
||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div>
|
||
|
||
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0037199%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (17)</a></li>
|
||
<li><a href="/gtr/tests?term=C0037199%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (17)</a></li>
|
||
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0037199%5bDISCUI%5d" target="_blank">See all (17)</a></total></li>
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Sinusitis" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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||
<div class="portlet mgSection" id="ID_121">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22sinusitis%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Sinusitis%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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<div class="portlet_content ln"><ul><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Sinusitis" target="_blank">MedlinePlus</a></li></ul></div>
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<li>
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<a href="/pubmed/clinical?term=Sinusitis" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=1&linkpostotal=2" target="_blank">PubMed Clinical Queries</a>
|
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</li>
|
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<li>
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||
<a href="/pubmed?term=Sinusitis%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=2&linkpostotal=2" target="_blank">Reviews in PubMed</a>
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</li>
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|
||
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|
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<!-- MedGen supplemental column ends here -->
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<div class="portlet brieflink">
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<h3>Related information</h3>
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<div class="portlet_content DiscoveryDbLinks">
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<ul>
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<li class="brieflinkpopper">
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<a class="brieflinkpopperctrl" href="/gtr/tests?term=C0037199[DISCUI]" ref="log$=recordlinks">GTR</a>
|
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<div class="brieflinkpop offscreen_noflow">Related information in GTR</div>
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||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests?term=C0037199[DISCUI]&test_type=Clinical" ref="log$=recordlinks">GTR(Clinical)</a>
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<div class="brieflinkpop offscreen_noflow">Clinical tests in GTR</div>
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||
</li>
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||
<li class="brieflinkpopper">
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||
<a class="brieflinkpopperctrl" href="/mesh?LinkName=medgen_mesh&from_uid=20772" ref="log$=recordlinks">MeSH</a>
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<div class="brieflinkpop offscreen_noflow">Related Medical Subject Headings</div>
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<a class="brieflinkpopperctrl" href="/pmc?LinkName=medgen_pmc&from_uid=20772" ref="log$=recordlinks">PMC Articles</a>
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<div class="brieflinkpop offscreen_noflow">Related information in PubMed Central Links</div>
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</li>
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<li class="brieflinkpopper">
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<a class="brieflinkpopperctrl" href="/pubmed?LinkName=medgen_pubmed&from_uid=20772" ref="log$=recordlinks">PubMed</a>
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<div class="brieflinkpop offscreen_noflow">Related literature resources in PubMed</div>
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<h3>Recent activity</h3>
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|
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<li>
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<a class="text-white" href="https://www.nih.gov/">NIH</a>
|
||
</li>
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||
<li>
|
||
<a class="text-white" href="https://www.hhs.gov/">HHS</a>
|
||
</li>
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||
<li>
|
||
<a class="text-white" href="https://www.usa.gov/">USA.gov</a>
|
||
</li>
|
||
</ul>
|
||
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|
||
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|
||
</div>
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||
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