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1116 lines
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109 KiB
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<!--
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UID=1929
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ConceptID=C0002962
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Angina pectoris</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1929</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0002962</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Sign or Symptom</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Angina Pectoris; Angor Pectoris; Stenocardia; Stenocardias</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Angina (194828000); Cardiac angina (194828000); Angina pectoris (194828000); Stenocardia (194828000); Anginal syndrome (194828000); AP - Angina pectoris (194828000); Ischemic heart disease - angina (194828000); Ischemic chest pain (225566008)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0001681">HP:0001681</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_content ln">Paroxysmal chest pain that occurs with exertion or stress and is related to myocardial ischemia. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Angina pectoris</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/18325" ref="tree=MeSH" title="MedGen record for Pathological process">Pathological process</a></span><ul><li><span class="TLline"><a href="/medgen/4347" ref="tree=MeSH" title="MedGen record for Disease">Disease</a></span><ul><li><span class="TLline"><a href="/medgen/232130" ref="tree=MeSH" title="MedGen record for Disorder by Site">Disorder by Site</a></span><ul><li><span class="TLline"><a href="/medgen/2848" ref="tree=MeSH" title="MedGen record for Disorder of cardiovascular system">Disorder of cardiovascular system</a></span><ul><li><span class="TLline"><a href="/medgen/116727" ref="tree=MeSH" title="MedGen record for Abnormality of the cardiovascular system">Abnormality of the cardiovascular system</a></span><ul><li><span class="TLline"><a href="/medgen/869166" ref="tree=MeSH" title="MedGen record for Abnormal cardiovascular system physiology">Abnormal cardiovascular system physiology</a></span><ul><li><span class="matched_ds">Angina pectoris</span><ul><li><span class="TLline"><a href="/medgen/149267" ref="tree=MeSH" title="MedGen record for Atypical angina">Atypical angina</a></span></li><li><span class="TLline"><a href="/medgen/104771" ref="tree=MeSH" title="MedGen record for Coronary microvascular disorder">Coronary microvascular disorder</a></span></li><li><span class="TLline"><a href="/medgen/296" ref="tree=MeSH" title="MedGen record for Intermediate coronary syndrome">Intermediate coronary syndrome</a></span><ul><li><span class="TLline"><a href="/medgen/295" ref="tree=MeSH" title="MedGen record for Prinzmetal angina">Prinzmetal angina</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/87401" ref="tree=MeSH" title="MedGen record for Stable angina">Stable angina</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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<div class="portlet mgSection" id="ID_112">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln clinfeat">
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||
<div class="divPopper rprt" id="rdis_8083"><div><strong>Fabry disease</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>8083</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0002986</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Fabry disease is the most common of the lysosomal storage disorders and results from deficient activity of the enzyme alpha-galactosidase A (a-Gal A), leading to progressive lysosomal deposition of globotriaosylceramide and its derivatives in cells throughout the body. The classic form, occurring in males with less than 1% a-Gal A enzyme activity, usually has its onset in childhood or adolescence with periodic crises of severe pain in the extremities (acroparesthesia), the appearance of vascular cutaneous lesions (angiokeratomas), sweating abnormalities (anhidrosis, hypohidrosis, and rarely hyperhidrosis), characteristic corneal and lenticular opacities, and proteinuria. Gradual deterioration of kidney function to end-stage kidney disease (ESKD) usually occurs in men in the third to fifth decade. In middle age, most males successfully treated for ESKD develop cardiac and/or cerebrovascular disease, a major cause of morbidity and mortality. Heterozygous females typically have milder symptoms at a later age of onset than males. Rarely, females may be relatively asymptomatic throughout a normal life span or may have symptoms as severe as those observed in males with the classic phenotype. In contrast, late-onset forms occur in males with greater than 1% a-Gal A activity. Clinical manifestations include cardiac disease, which usually presents in the sixth to eighth decade with left ventricular hypertrophy, cardiomyopathy, arrhythmia, and proteinuria; kidney failure, associated with ESKD but without the skin lesions or pain; or cerebrovascular disease presenting as stroke or transient ischemic attack.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/8083">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_46123"><div><strong>Hutchinson-Gilford syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>46123</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0033300</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hutchinson-Gilford progeria syndrome (HGPS) is characterized by clinical features that typically develop in childhood and resemble some features of accelerated aging. Children with HGPS usually appear normal at birth. Profound failure to thrive occurs during the first year. Characteristic facial features include head that is disproportionately large for the face, narrow nasal ridge, narrow nasal tip, thin vermilion of the upper and lower lips, small mouth, and retro- and micrognathia. Common features include loss of subcutaneous fat, delayed eruption and loss of primary teeth, abnormal skin with small outpouchings over the abdomen and upper thighs, alopecia, nail dystrophy, coxa valga, and progressive joint contractures. Later findings include low-frequency conductive hearing loss, dental crowding, and partial lack of secondary tooth eruption. Motor and mental development is normal. Death occurs as a result of complications of severe atherosclerosis, either cardiac disease (myocardial infarction or heart failure) or cerebrovascular disease (stroke), generally between ages six and 20 years (average 14.5 years) without lonafarnib treatment or cardiac surgery intervention. Average life span is extended to approximately 17-19.5 years with lonafarnib therapy.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/46123">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_116041"><div><strong>Cholestanol storage disease</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>116041</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0238052</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Cerebrotendinous xanthomatosis (CTX) is a lipid storage disease characterized by infantile-onset diarrhea, childhood-onset cataract, adolescent- to young adult-onset tendon xanthomas, and adult-onset progressive neurologic dysfunction (dementia, psychiatric disturbances, pyramidal and/or cerebellar signs, dystonia, atypical parkinsonism, peripheral neuropathy, and seizures). Chronic diarrhea from infancy and/or neonatal cholestasis may be the earliest clinical manifestation. In approximately 75% of affected individuals, cataracts are the first finding, often appearing in the first decade of life. Xanthomas appear in the second or third decade; they occur on the Achilles tendon, the extensor tendons of the elbow and hand, the patellar tendon, and the neck tendons. Xanthomas have been reported in the lung, bones, and central nervous system. Some individuals show cognitive impairment from early infancy, whereas the majority have normal or only slightly impaired intellectual function until puberty; dementia with slow deterioration in intellectual abilities occurs in the third decade in more than 50% of individuals. Neuropsychiatric symptoms such as behavioral changes, hallucinations, agitation, aggression, depression, and suicide attempts may be prominent. Pyramidal signs (i.e., spasticity) and/or cerebellar signs almost invariably become evident between ages 20 and 30 years. The biochemical abnormalities that distinguish CTX from other conditions with xanthomas include high plasma and tissue cholestanol concentration, normal-to-low plasma cholesterol concentration, decreased chenodeoxycholic acid (CDCA), increased concentration of bile alcohols and their glyconjugates, and increased concentrations of cholestanol and apolipoprotein B in cerebrospinal fluid.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/116041">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_698415"><div><strong>Autosomal recessive inherited pseudoxanthoma elasticum</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>698415</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1275116</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Pseudoxanthoma elasticum (PXE) is a systemic disorder that affects the elastic tissue of the skin, the eye, and vascular system. Individuals most commonly present with angioid streaks of the retina found on routine eye examination or associated with retinal hemorrhage and/or characteristic papules in the skin. The most frequent cause of morbidity and disability in PXE is reduced vision due to complications of subretinal neovascularizations and macular atrophy. Other manifestations include premature gastrointestinal angina and/or bleeding, intermittent claudication of arm and leg muscles, stroke, renovascular hypertension, and cardiovascular complications (angina/myocardial infarction). Most affected individuals live a normal life span.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/698415">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_349383"><div><strong>Hypertrophic cardiomyopathy 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>349383</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1861864</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hypertrophic cardiomyopathy is a heart condition characterized by thickening (hypertrophy) of the heart (cardiac) muscle. When multiple members of a family have the condition, it is known as familial hypertrophic cardiomyopathy. Hypertrophic cardiomyopathy also occurs in people with no family history; these cases are considered nonfamilial hypertrophic cardiomyopathy. \n\nIn familial hypertrophic cardiomyopathy, cardiac thickening usually occurs in the interventricular septum, which is the muscular wall that separates the lower left chamber of the heart (the left ventricle) from the lower right chamber (the right ventricle). In some people, thickening of the interventricular septum impedes the flow of oxygen-rich blood from the heart, which may lead to an abnormal heart sound during a heartbeat (heart murmur) and other signs and symptoms of the condition. Other affected individuals do not have physical obstruction of blood flow, but the pumping of blood is less efficient, which can also lead to symptoms of the condition. Familial hypertrophic cardiomyopathy often begins in adolescence or young adulthood, although it can develop at any time throughout life.\n\nThe symptoms of familial hypertrophic cardiomyopathy are variable, even within the same family. Many affected individuals have no symptoms. Other people with familial hypertrophic cardiomyopathy may experience chest pain; shortness of breath, especially with physical exertion; a sensation of fluttering or pounding in the chest (palpitations); lightheadedness; dizziness; and fainting.\n\nNonfamilial hypertrophic cardiomyopathy tends to be milder. This form typically begins later in life than familial hypertrophic cardiomyopathy, and affected individuals have a lower risk of serious cardiac events and sudden death than people with the familial form.\n\nWhile most people with familial hypertrophic cardiomyopathy are symptom-free or have only mild symptoms, this condition can have serious consequences. It can cause abnormal heart rhythms (arrhythmias) that may be life threatening. People with familial hypertrophic cardiomyopathy have an increased risk of sudden death, even if they have no other symptoms of the condition. A small number of affected individuals develop potentially fatal heart failure, which may require heart transplantation.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/349383">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_357280"><div><strong>Pseudoxanthoma elasticum, forme fruste</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>357280</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1867450</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Pseudoxanthoma elasticum (PXE) is a systemic disorder that affects the elastic tissue of the skin, the eye, and vascular system. Individuals most commonly present with angioid streaks of the retina found on routine eye examination or associated with retinal hemorrhage and/or characteristic papules in the skin. The most frequent cause of morbidity and disability in PXE is reduced vision due to complications of subretinal neovascularizations and macular atrophy. Other manifestations include premature gastrointestinal angina and/or bleeding, intermittent claudication of arm and leg muscles, stroke, renovascular hypertension, and cardiovascular complications (angina/myocardial infarction). Most affected individuals live a normal life span.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/357280">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_436962"><div><strong>Hypertrophic cardiomyopathy 11</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>436962</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2677506</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">An autosomal dominant subtype of familial hypertrophic cardiomyopathy caused by mutation(s) in the ACTC1 gene, encoding actin, alpha cardiac muscle 1.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/436962">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_442487"><div><strong>Hypertrophic cardiomyopathy 13</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>442487</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2750472</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Any hypertrophic cardiomyopathy in which the cause of the disease is a mutation in the TNNC1 gene.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/442487">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_462614"><div><strong>Hypertrophic cardiomyopathy 17</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>462614</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3151264</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">An autosomal dominant subtype of familial hypertrophic cardiomyopathy caused by mutation(s) in the JPH2 gene, encoding junctophilin-2.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/462614">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_462816"><div><strong>Hyperlipidemia due to hepatic triglyceride lipase deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>462816</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3151466</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hepatic lipase deficiency is characterized by premature atherosclerosis, elevated total cholesterol, triglycerides (TG), and very low density lipoprotein (VLDL), as well as TG-rich low density lipoprotein (LDL) and HDL subfractions (summary by Hegele et al., 1991).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/462816">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1802382"><div><strong>Pulmonary hypertension, primary, autosomal recessive</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1802382</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5676877</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Primary pulmonary hypertension-5 (PPH5) is an autosomal recessive disorder characterized by the onset of pulmonary arterial hypertension in infancy, resulting in right heart dysfunction and ultimately right heart failure. Death in early childhood is common (Machado et al., 2022). For a discussion of genetic heterogeneity of primary pulmonary hypertension, see PPH1 (178600).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1802382">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_698415" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Autosomal recessive inherited pseudoxanthoma elasticum</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_116041" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cholestanol storage disease</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_8083" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Fabry disease</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_46123" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hutchinson-Gilford syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_462816" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hyperlipidemia due to hepatic triglyceride lipase deficiency</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (11)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_436962" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hypertrophic cardiomyopathy 11</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_442487" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hypertrophic cardiomyopathy 13</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_462614" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hypertrophic cardiomyopathy 17</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_349383" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hypertrophic cardiomyopathy 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_357280" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Pseudoxanthoma elasticum, forme fruste</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1802382" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Pulmonary hypertension, primary, autosomal recessive</a></div></span></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/31504439">2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Knuuti J,
|
||
Wijns W,
|
||
Saraste A,
|
||
Capodanno D,
|
||
Barbato E,
|
||
Funck-Brentano C,
|
||
Prescott E,
|
||
Storey RF,
|
||
Deaton C,
|
||
Cuisset T,
|
||
Agewall S,
|
||
Dickstein K,
|
||
Edvardsen T,
|
||
Escaned J,
|
||
Gersh BJ,
|
||
Svitil P,
|
||
Gilard M,
|
||
Hasdai D,
|
||
Hatala R,
|
||
Mahfoud F,
|
||
Masip J,
|
||
Muneretto C,
|
||
Valgimigli M,
|
||
Achenbach S,
|
||
Bax JJ;
|
||
ESC Scientific Document Group</span><br />
|
||
<span class="medgenPMjournal">Eur Heart J</span>
|
||
2020 Jan 14;41(3):407-477.
|
||
doi: 10.1093/eurheartj/ehz425.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31504439" target="_blank">31504439</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28196437">Angina and Its Management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kloner RA,
|
||
Chaitman B</span><br />
|
||
<span class="medgenPMjournal">J Cardiovasc Pharmacol Ther</span>
|
||
2017 May;22(3):199-209.
|
||
Epub 2016 Dec 14
|
||
doi: 10.1177/1074248416679733.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28196437" target="_blank">28196437</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23996286">2013 ESC guidelines on the management of stable coronary artery disease: the Task Force on the management of stable coronary artery disease of the European Society of Cardiology.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Task Force Members,
|
||
Montalescot G,
|
||
Sechtem U,
|
||
Achenbach S,
|
||
Andreotti F,
|
||
Arden C,
|
||
Budaj A,
|
||
Bugiardini R,
|
||
Crea F,
|
||
Cuisset T,
|
||
Di Mario C,
|
||
Ferreira JR,
|
||
Gersh BJ,
|
||
Gitt AK,
|
||
Hulot JS,
|
||
Marx N,
|
||
Opie LH,
|
||
Pfisterer M,
|
||
Prescott E,
|
||
Ruschitzka F,
|
||
Sabaté M,
|
||
Senior R,
|
||
Taggart DP,
|
||
van der Wall EE,
|
||
Vrints CJ;
|
||
ESC Committee for Practice Guidelines,
|
||
Zamorano JL,
|
||
Achenbach S,
|
||
Baumgartner H,
|
||
Bax JJ,
|
||
Bueno H,
|
||
Dean V,
|
||
Deaton C,
|
||
Erol C,
|
||
Fagard R,
|
||
Ferrari R,
|
||
Hasdai D,
|
||
Hoes AW,
|
||
Kirchhof P,
|
||
Knuuti J,
|
||
Kolh P,
|
||
Lancellotti P,
|
||
Linhart A,
|
||
Nihoyannopoulos P,
|
||
Piepoli MF,
|
||
Ponikowski P,
|
||
Sirnes PA,
|
||
Tamargo JL,
|
||
Tendera M,
|
||
Torbicki A,
|
||
Wijns W,
|
||
Windecker S;
|
||
Document Reviewers,
|
||
Knuuti J,
|
||
Valgimigli M,
|
||
Bueno H,
|
||
Claeys MJ,
|
||
Donner-Banzhoff N,
|
||
Erol C,
|
||
Frank H,
|
||
Funck-Brentano C,
|
||
Gaemperli O,
|
||
Gonzalez-Juanatey JR,
|
||
Hamilos M,
|
||
Hasdai D,
|
||
Husted S,
|
||
James SK,
|
||
Kervinen K,
|
||
Kolh P,
|
||
Kristensen SD,
|
||
Lancellotti P,
|
||
Maggioni AP,
|
||
Piepoli MF,
|
||
Pries AR,
|
||
Romeo F,
|
||
Rydén L,
|
||
Simoons ML,
|
||
Sirnes PA,
|
||
Steg PG,
|
||
Timmis A,
|
||
Wijns W,
|
||
Windecker S,
|
||
Yildirir A,
|
||
Zamorano JL</span><br />
|
||
<span class="medgenPMjournal">Eur Heart J</span>
|
||
2013 Oct;34(38):2949-3003.
|
||
Epub 2013 Aug 30
|
||
doi: 10.1093/eurheartj/eht296.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23996286" target="_blank">23996286</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22angina%20pectoris%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (942)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nice.org.uk/guidance/ng185" target="_blank">UK NICE guideline NG185, Acute coronary syndromes, 2020</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38662950">Ballerina foot in heart.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rengan A,
|
||
Agstam S,
|
||
Mantoo MR,
|
||
Ramakrishnan S</span><br />
|
||
<span class="medgenPMjournal">J Invasive Cardiol</span>
|
||
2024 Sep;36(9)
|
||
doi: 10.25270/jic/24.00116.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38662950" target="_blank">38662950</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33036723">Refractory Angina-Unsolved Problem.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Makowski M,
|
||
Makowska JS,
|
||
Zielińska M</span><br />
|
||
<span class="medgenPMjournal">Cardiol Clin</span>
|
||
2020 Nov;38(4):629-637.
|
||
Epub 2020 Sep 17
|
||
doi: 10.1016/j.ccl.2020.07.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33036723" target="_blank">33036723</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30197243">Vasospastic angina: A literature review of current evidence.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Picard F,
|
||
Sayah N,
|
||
Spagnoli V,
|
||
Adjedj J,
|
||
Varenne O</span><br />
|
||
<span class="medgenPMjournal">Arch Cardiovasc Dis</span>
|
||
2019 Jan;112(1):44-55.
|
||
Epub 2018 Sep 7
|
||
doi: 10.1016/j.acvd.2018.08.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30197243" target="_blank">30197243</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/341754">Establishing the diagnosis and etiology of angina pectoris.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Groves BM</span><br />
|
||
<span class="medgenPMjournal">Angiology</span>
|
||
1977 Dec;28(12):817-31.
|
||
doi: 10.1177/000331977702801202.
|
||
<span class="bold">PMID: </span><a href="/pubmed/341754" target="_blank">341754</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/5662192">Propranolol in hypertension.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tewari SN,
|
||
Grant RH</span><br />
|
||
<span class="medgenPMjournal">Postgrad Med J</span>
|
||
1968 Jul;44(513):509-12.
|
||
doi: 10.1136/pgmj.44.513.509.
|
||
<span class="bold">PMID: </span><a href="/pubmed/5662192" target="_blank">5662192</a><a href="/pmc/articles/PMC2466278" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Angina%20pectoris%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (13334)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36724392">How to deal with myocardial bridge and angina.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ghizzoni G,
|
||
Ancona MB,
|
||
Gentile D,
|
||
Bellini B,
|
||
Ferri L,
|
||
Russo F,
|
||
Vella C,
|
||
Montorfano M</span><br />
|
||
<span class="medgenPMjournal">J Cardiovasc Med (Hagerstown)</span>
|
||
2023 Mar 1;24(3):219-220.
|
||
Epub 2023 Jan 24
|
||
doi: 10.2459/JCM.0000000000001428.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36724392" target="_blank">36724392</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33792542">Reducing refractory angina.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">de Silva R,
|
||
Cheng K</span><br />
|
||
<span class="medgenPMjournal">EuroIntervention</span>
|
||
2021 Apr 2;16(18):e1466-e1467.
|
||
doi: 10.4244/EIJV16I18A265.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33792542" target="_blank">33792542</a><a href="/pmc/articles/PMC9707452" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/3321016">Angina pectoris.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gribbin B</span><br />
|
||
<span class="medgenPMjournal">Practitioner</span>
|
||
1987 May 22;231(1430):741-2, 745-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/3321016" target="_blank">3321016</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/3297506">Angina pectoris: diagnosis, treatment, and prognosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dehmer GJ</span><br />
|
||
<span class="medgenPMjournal">Curr Probl Cardiol</span>
|
||
1987 Apr;12(4):213-81.
|
||
doi: 10.1016/0146-2806(87)90008-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/3297506" target="_blank">3297506</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/5061002">Angina pectoris.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kerr RA</span><br />
|
||
<span class="medgenPMjournal">J Am Pharm Assoc</span>
|
||
1972 Apr;12(4):178-82.
|
||
doi: 10.1016/s0003-0465(16)32179-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/5061002" target="_blank">5061002</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Angina%20pectoris%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (9746)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39109689">Angina Pectoris and Orbita 2 Trial: Reflections on the Future of Angina Treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Martins EB,
|
||
Lima EG,
|
||
Linhares Filho JPP,
|
||
Pinesi HT,
|
||
Pitta FG,
|
||
Serrano Júnior CV</span><br />
|
||
<span class="medgenPMjournal">Arq Bras Cardiol</span>
|
||
2024;121(6):e20230848.
|
||
Epub 2024 Aug 2
|
||
doi: 10.36660/abc.20230848.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39109689" target="_blank">39109689</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12528309">ZK-807834. Berlex.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sinha U</span><br />
|
||
<span class="medgenPMjournal">Curr Opin Investig Drugs</span>
|
||
2002 Dec;3(12):1736-41.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12528309" target="_blank">12528309</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/3117861">Thrombolytic therapy for unstable angina pectoris: rationale and results.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gold HK,
|
||
Johns JA,
|
||
Leinbach RC,
|
||
Yasuda T,
|
||
Collen D</span><br />
|
||
<span class="medgenPMjournal">J Am Coll Cardiol</span>
|
||
1987 Nov;10(5 Suppl B):91B-95B.
|
||
doi: 10.1016/s0735-1097(87)80433-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/3117861" target="_blank">3117861</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/6641092">Alinidine in angina.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Meinertz T,
|
||
Kasper W,
|
||
Meier R,
|
||
Wiegand U,
|
||
Bechtold H,
|
||
Förster I,
|
||
Pop T,
|
||
Jähnchen E</span><br />
|
||
<span class="medgenPMjournal">Clin Pharmacol Ther</span>
|
||
1983 Dec;34(6):770-6.
|
||
doi: 10.1038/clpt.1983.248.
|
||
<span class="bold">PMID: </span><a href="/pubmed/6641092" target="_blank">6641092</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/6337762">Glucose and lipid metabolism during acebutolol and propranolol therapy of angina in nondiabetic patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Birnbaum J,
|
||
DiBianco R,
|
||
Becker KL,
|
||
Muesing R,
|
||
Costello RB,
|
||
Singh SN,
|
||
Gottdiener JS,
|
||
Fletcher RD</span><br />
|
||
<span class="medgenPMjournal">Clin Pharmacol Ther</span>
|
||
1983 Mar;33(3):294-300.
|
||
doi: 10.1038/clpt.1983.36.
|
||
<span class="bold">PMID: </span><a href="/pubmed/6337762" target="_blank">6337762</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Angina%20pectoris%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (12178)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35261278">Risk Factors of Cardiac Death for Elderly Patients with Severe Chronic Kidney Disease after Percutaneous Coronary Intervention.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang Y,
|
||
Zhai G,
|
||
Wang J,
|
||
Zhou Y</span><br />
|
||
<span class="medgenPMjournal">Clin Appl Thromb Hemost</span>
|
||
2022 Jan-Dec;28:10760296221081848.
|
||
doi: 10.1177/10760296221081848.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35261278" target="_blank">35261278</a><a href="/pmc/articles/PMC8918957" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34342407">Analysis of clinical efficacy and incidence of complications of percutaneous coronary intervention in the treatment of angina pectoris in elderly patients with coronary heart disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wei F,
|
||
Zhang J,
|
||
Bao X</span><br />
|
||
<span class="medgenPMjournal">Minerva Surg</span>
|
||
2022 Jun;77(3):309-310.
|
||
Epub 2021 Aug 3
|
||
doi: 10.23736/S2724-5691.21.09039-0.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34342407" target="_blank">34342407</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27115377">Association Between Rotating Night Shift Work and Risk of Coronary Heart Disease Among Women.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vetter C,
|
||
Devore EE,
|
||
Wegrzyn LR,
|
||
Massa J,
|
||
Speizer FE,
|
||
Kawachi I,
|
||
Rosner B,
|
||
Stampfer MJ,
|
||
Schernhammer ES</span><br />
|
||
<span class="medgenPMjournal">JAMA</span>
|
||
2016 Apr 26;315(16):1726-34.
|
||
doi: 10.1001/jama.2016.4454.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27115377" target="_blank">27115377</a><a href="/pmc/articles/PMC5102147" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8960457">Diagnostic procedures for myocardial ischaemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gottlieb SO</span><br />
|
||
<span class="medgenPMjournal">Eur Heart J</span>
|
||
1996 Dec;17 Suppl G:53-8.
|
||
doi: 10.1093/eurheartj/17.suppl_g.53.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8960457" target="_blank">8960457</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2044105">Coronary heart disease: black-white differences.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cooper RS,
|
||
Ghali JK</span><br />
|
||
<span class="medgenPMjournal">Cardiovasc Clin</span>
|
||
1991;21(3):205-25.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2044105" target="_blank">2044105</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Angina%20pectoris%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (8391)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/31709984">1-Year Outcomes of Angina Management Guided by Invasive Coronary Function Testing (CorMicA).</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ford TJ,
|
||
Stanley B,
|
||
Sidik N,
|
||
Good R,
|
||
Rocchiccioli P,
|
||
McEntegart M,
|
||
Watkins S,
|
||
Eteiba H,
|
||
Shaukat A,
|
||
Lindsay M,
|
||
Robertson K,
|
||
Hood S,
|
||
McGeoch R,
|
||
McDade R,
|
||
Yii E,
|
||
McCartney P,
|
||
Corcoran D,
|
||
Collison D,
|
||
Rush C,
|
||
Sattar N,
|
||
McConnachie A,
|
||
Touyz RM,
|
||
Oldroyd KG,
|
||
Berry C</span><br />
|
||
<span class="medgenPMjournal">JACC Cardiovasc Interv</span>
|
||
2020 Jan 13;13(1):33-45.
|
||
Epub 2019 Nov 11
|
||
doi: 10.1016/j.jcin.2019.11.001.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31709984" target="_blank">31709984</a><a href="/pmc/articles/PMC8310942" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31912714">Evaluation of acute chest pain: Evolving paradigm of coronary risk scores and imaging.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Alderwish E,
|
||
Schultz E,
|
||
Kassam Z,
|
||
Poon M,
|
||
Coplan N</span><br />
|
||
<span class="medgenPMjournal">Rev Cardiovasc Med</span>
|
||
2019 Dec 30;20(4):231-244.
|
||
doi: 10.31083/j.rcm.2019.04.589.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31912714" target="_blank">31912714</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30197243">Vasospastic angina: A literature review of current evidence.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Picard F,
|
||
Sayah N,
|
||
Spagnoli V,
|
||
Adjedj J,
|
||
Varenne O</span><br />
|
||
<span class="medgenPMjournal">Arch Cardiovasc Dis</span>
|
||
2019 Jan;112(1):44-55.
|
||
Epub 2018 Sep 7
|
||
doi: 10.1016/j.acvd.2018.08.002.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30197243" target="_blank">30197243</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28279382">Trials of Imaging Use in the Emergency Department for Acute Chest Pain.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Raff GL,
|
||
Hoffmann U,
|
||
Udelson JE</span><br />
|
||
<span class="medgenPMjournal">JACC Cardiovasc Imaging</span>
|
||
2017 Mar;10(3):338-349.
|
||
doi: 10.1016/j.jcmg.2016.10.015.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28279382" target="_blank">28279382</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/19282605">Silent myocardial ischemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gutterman DD</span><br />
|
||
<span class="medgenPMjournal">Circ J</span>
|
||
2009 May;73(5):785-97.
|
||
Epub 2009 Mar 13
|
||
doi: 10.1253/circj.cj-08-1209.
|
||
<span class="bold">PMID: </span><a href="/pubmed/19282605" target="_blank">19282605</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Angina%20pectoris%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (7621)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/36130740">Association of gestational diabetes mellitus with overall and type specific cardiovascular and cerebrovascular diseases: systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Xie W,
|
||
Wang Y,
|
||
Xiao S,
|
||
Qiu L,
|
||
Yu Y,
|
||
Zhang Z</span><br />
|
||
<span class="medgenPMjournal">BMJ</span>
|
||
2022 Sep 21;378:e070244.
|
||
doi: 10.1136/bmj-2022-070244.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36130740" target="_blank">36130740</a><a href="/pmc/articles/PMC9490552" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34741536">Exercise-based cardiac rehabilitation for coronary heart disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dibben G,
|
||
Faulkner J,
|
||
Oldridge N,
|
||
Rees K,
|
||
Thompson DR,
|
||
Zwisler AD,
|
||
Taylor RS</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2021 Nov 6;11(11):CD001800.
|
||
doi: 10.1002/14651858.CD001800.pub4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34741536" target="_blank">34741536</a><a href="/pmc/articles/PMC8571912" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29884191">Prevalence of cardiovascular disease in type 2 diabetes: a systematic literature review of scientific evidence from across the world in 2007-2017.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Einarson TR,
|
||
Acs A,
|
||
Ludwig C,
|
||
Panton UH</span><br />
|
||
<span class="medgenPMjournal">Cardiovasc Diabetol</span>
|
||
2018 Jun 8;17(1):83.
|
||
doi: 10.1186/s12933-018-0728-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29884191" target="_blank">29884191</a><a href="/pmc/articles/PMC5994068" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29212370">Psychological interventions for coronary heart disease: Cochrane systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Richards SH,
|
||
Anderson L,
|
||
Jenkinson CE,
|
||
Whalley B,
|
||
Rees K,
|
||
Davies P,
|
||
Bennett P,
|
||
Liu Z,
|
||
West R,
|
||
Thompson DR,
|
||
Taylor RS</span><br />
|
||
<span class="medgenPMjournal">Eur J Prev Cardiol</span>
|
||
2018 Feb;25(3):247-259.
|
||
Epub 2017 Dec 7
|
||
doi: 10.1177/2047487317739978.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29212370" target="_blank">29212370</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26764059">Exercise-Based Cardiac Rehabilitation for Coronary Heart Disease: Cochrane Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Anderson L,
|
||
Oldridge N,
|
||
Thompson DR,
|
||
Zwisler AD,
|
||
Rees K,
|
||
Martin N,
|
||
Taylor RS</span><br />
|
||
<span class="medgenPMjournal">J Am Coll Cardiol</span>
|
||
2016 Jan 5;67(1):1-12.
|
||
doi: 10.1016/j.jacc.2015.10.044.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26764059" target="_blank">26764059</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Angina%20pectoris%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (215)</a></div></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22angina%20pectoris%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Angina%20pectoris%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nice.org.uk/guidance/ng185">NICE, 2020</a><div>UK NICE guideline NG185, Acute coronary syndromes, 2020</div></li></ul></div>
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