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<meta name="keywords" content="C0034212, disease or syndrome, purulent dermatitis, pus-filled lesion, pyoderma, pyodermas, pyodermia, pyogenic dermatitis, pyogenic infection of skin and subcutis, septic dermatitis, suppurative dermatitis, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Any manifestation of a skin disease associated with the production of pus." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
UID=18783
ConceptID=C0034212
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Pyoderma</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>18783</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0034212</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
<td>Pyodermas</td></tr>
<tr><td><span class="bold">SNOMED CT: </span></td>
<td>Pyoderma (70759006); Pyodermia (70759006); Purulent dermatitis (70759006); Suppurative dermatitis (70759006); Septic dermatitis (70759006); Pyogenic dermatitis (70759006); Pyogenic infection of skin and subcutis (70759006)</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0000999">HP:0000999</a></td></tr>
<tr><td>Monarch Initiative:</td>
<td><a href="https://monarchinitiative.org/disease/MONDO:0002922" target="_blank">MONDO:0002922</a></td></tr>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">Any manifestation of a skin disease associated with the production of pus. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
</div>
<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Pyoderma</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867388" ref="tree=MeSH" title="MedGen record for Abnormality of the immune system">Abnormality of the immune system</a></span><ul><li><span class="TLline"><a href="/medgen/869194" ref="tree=MeSH" title="MedGen record for Abnormality of immune system physiology">Abnormality of immune system physiology</a></span><ul><li><span class="TLline"><a href="/medgen/1685049" ref="tree=MeSH" title="MedGen record for Unusual infection">Unusual infection</a></span><ul><li><span class="TLline"><a href="/medgen/65998" ref="tree=MeSH" title="MedGen record for Recurrent infections">Recurrent infections</a></span><ul><li><span class="TLline"><a href="/medgen/334943" ref="tree=MeSH" title="MedGen record for Recurrent bacterial infections">Recurrent bacterial infections</a></span><ul><li><span class="TLline"><a href="/medgen/322727" ref="tree=MeSH" title="MedGen record for Recurrent bacterial skin infections">Recurrent bacterial skin infections</a></span><ul><li><span class="matched_ds">Pyoderma</span><ul><li><span class="TLline"><a href="/medgen/8541" ref="tree=MeSH" title="MedGen record for Ecthyma">Ecthyma</a></span></li><li><span class="TLline"><a href="/medgen/43224" ref="tree=MeSH" title="MedGen record for Pyoderma gangrenosum">Pyoderma gangrenosum</a></span><ul><li><span class="TLline"><a href="/medgen/590609" ref="tree=MeSH" title="MedGen record for Bullous pyoderma gangrenosum">Bullous pyoderma gangrenosum</a></span></li><li><span class="TLline"><a href="/medgen/1814456" ref="tree=MeSH" title="MedGen record for Classic pyoderma gangrenosum">Classic pyoderma gangrenosum</a></span></li><li><span class="TLline"><a href="/medgen/1814476" ref="tree=MeSH" title="MedGen record for Pustular pyoderma gangrenosum">Pustular pyoderma gangrenosum</a></span></li><li><span class="TLline"><a href="/medgen/1842944" ref="tree=MeSH" title="MedGen record for Vegetative pyoderma gangrenosum">Vegetative pyoderma gangrenosum</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_112">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln clinfeat">
<div class="divPopper rprt" id="rdis_101814"><div><strong>T-lymphocyte deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>101814</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0152094</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">T-cell immunodeficiency with thymic aplasia (TIDTA) is an autosomal recessive disorder that is often detected at birth through newborn SCID screening with the finding of decreased T-cell receptor excision circles (TRECs). Affected individuals have selective hypo- or aplasia of the thymus, which results in T-cell immunodeficiency due to impaired T-cell development and increased susceptibility to viral infections. The phenotype is similar to T-/B+/NK+ SCID. Some patients may die in childhood; thymus transplantation may be curative (summary by Du et al., 2019).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/101814">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_65123"><div><strong>X-linked agammaglobulinemia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>65123</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0221026</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">X-linked agammaglobulinemia (XLA) is characterized by recurrent bacterial infections in affected males in the first two years of life. Recurrent otitis is the most common infection prior to diagnosis. Conjunctivitis, sinopulmonary infections, diarrhea, and skin infections are also frequently seen. Approximately 60% of individuals with XLA are recognized as having immunodeficiency when they develop a severe, life-threatening infection such as pneumonia, empyema, meningitis, sepsis, cellulitis, or septic arthritis. S pneumoniae and H influenzae are the most common organisms found prior to diagnosis and may continue to cause sinusitis and otitis after diagnosis and the initiation of gammaglobulin substitution therapy. Severe, difficult-to-treat enteroviral infections (often manifesting as dermatomyositis or chronic meningoencephalitis) can be prevented by this treatment. The prognosis for individuals with XLA has improved markedly in the last 25 years as a result of earlier diagnosis, the development of preparations of gammaglobulin that allow normal concentrations of serum immunoglobulin G to be achieved, and more liberal use of antibiotics.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/65123">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_98348"><div><strong>Actinic prurigo</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>98348</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0406217</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Hereditary polymorphic light eruption is a form of photosensitivity found in the American Indians of the central plains of Canada and the United States and in the Indians of Central and South America. The disorder has also been called familial actinic prurigo, solar dermatitis, and hydroa aestivale. In northern latitudes, skin lesions appear on exposed areas early in spring, become severe during the summer, and abate in the fall. Usually the disorder appears in childhood with eczematous crusted eruptions on the face and arms. Fissured, crusted exudative cheilitis develops on the lips, especially the lower lip. The dorsum of the hands, the laterodorsal aspects of the forearms, and the lower half of the arms often show excoriated papular and nodular lesions. Children frequently have complicating pyoderma. Adults usually exhibit an erythematous plaquelike eruption on the face and other exposed areas. The disease is more severe in children than in adults. Glomerulonephritis can follow streptococcal pyoderma (summary by Fusaro and Johnson, 1980).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/98348">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_141630"><div><strong>X-linked agammaglobulinemia with growth hormone deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>141630</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information."><span class="highlight" style="background-color:">C0472813</span></a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">IGHD3 is characterized by agammaglobulinemia and markedly reduced numbers of B cells, short stature, delayed bone age, and good response to treatment with growth hormone (summary by Conley et al., 1991).&#13; For general phenotypic information and a discussion of genetic heterogeneity of IGHD, see 262400.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/141630">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_442630"><div><strong>Inflammatory bowel disease 28</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>442630</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C2751053</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">An autosomal recessive condition caused by mutation(s) in the IL10RA gene, encoding interleukin-10 receptor subunit alpha. It is characterized by early-onset chronic relapsing intestinal inflammation.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/442630">Condition Record</a></div></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_98348" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Actinic prurigo</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_442630" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Inflammatory bowel disease 28</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_101814" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">T-lymphocyte deficiency</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_65123" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">X-linked agammaglobulinemia</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_141630" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">X-linked agammaglobulinemia with growth hormone deficiency</a></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/37610614">Pyoderma Gangrenosum: Treatment Options.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Dissemond J,
Marzano AV,
Hampton PJ,
Ortega-Loayza AG</span><br />
<span class="medgenPMjournal">Drugs</span>
2023 Sep;83(14):1255-1267.
Epub 2023 Aug 23
doi: 10.1007/s40265-023-01931-3.
<span class="bold">PMID: </span><a href="/pubmed/37610614" target="_blank">37610614</a><a href="/pmc/articles/PMC10511384" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33493574">Comorbidity screening in hidradenitis suppurativa: Evidence-based recommendations from the US and Canadian Hidradenitis Suppurativa Foundations.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Garg A,
Malviya N,
Strunk A,
Wright S,
Alavi A,
Alhusayen R,
Alikhan A,
Daveluy SD,
Delorme I,
Goldfarb N,
Gulliver W,
Hamzavi I,
Jaleel T,
Kimball AB,
Kirby JS,
Kirchhof MG,
Lester J,
Lev-Tov H,
Lowes MA,
Micheletti R,
Orenstein LA,
Piguet V,
Sayed C,
Tan J,
Naik HB</span><br />
<span class="medgenPMjournal">J Am Acad Dermatol</span>
2022 May;86(5):1092-1101.
Epub 2021 Jan 23
doi: 10.1016/j.jaad.2021.01.059.
<span class="bold">PMID: </span><a href="/pubmed/33493574" target="_blank">33493574</a><a href="/pmc/articles/PMC8298595" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34358489">Extraintestinal Manifestations of Inflammatory Bowel Disease: Current Concepts, Treatment, and Implications for Disease Management.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Rogler G,
Singh A,
Kavanaugh A,
Rubin DT</span><br />
<span class="medgenPMjournal">Gastroenterology</span>
2021 Oct;161(4):1118-1132.
Epub 2021 Aug 3
doi: 10.1053/j.gastro.2021.07.042.
<span class="bold">PMID: </span><a href="/pubmed/34358489" target="_blank">34358489</a><a href="/pmc/articles/PMC8564770" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22pyoderma%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (242)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/38423686">Pediatric Neutrophilic Dermatoses.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Moreno-Artero E,
Torrelo A</span><br />
<span class="medgenPMjournal">Dermatol Clin</span>
2024 Apr;42(2):267-283.
Epub 2024 Jan 20
doi: 10.1016/j.det.2023.12.005.
<span class="bold">PMID: </span><a href="/pubmed/38423686" target="_blank">38423686</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35870984">Neutrophilic dermatoses.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Delaleu J,
Lepelletier C,
Calugareanu A,
De Masson A,
Charvet E,
Petit A,
Giurgea I,
Amselem S,
Karabina S,
Jachiet M,
Mahevas T,
Ram-Wolff C,
Vignon-Pennamen MD,
Bagot M,
Battistella M,
Bouaziz JD</span><br />
<span class="medgenPMjournal">Rev Med Interne</span>
2022 Dec;43(12):727-738.
Epub 2022 Jul 20
doi: 10.1016/j.revmed.2022.06.007.
<span class="bold">PMID: </span><a href="/pubmed/35870984" target="_blank">35870984</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35606650">Pyoderma Gangrenosum: An Updated Literature Review on Established and Emerging Pharmacological Treatments.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Maronese CA,
Pimentel MA,
Li MM,
Genovese G,
Ortega-Loayza AG,
Marzano AV</span><br />
<span class="medgenPMjournal">Am J Clin Dermatol</span>
2022 Sep;23(5):615-634.
Epub 2022 May 24
doi: 10.1007/s40257-022-00699-8.
<span class="bold">PMID: </span><a href="/pubmed/35606650" target="_blank">35606650</a><a href="/pmc/articles/PMC9464730" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32618443">PAPA spectrum disorders.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Genovese G,
Moltrasio C,
Garcovich S,
Marzano AV</span><br />
<span class="medgenPMjournal">G Ital Dermatol Venereol</span>
2020 Oct;155(5):542-550.
Epub 2020 Jul 2
doi: 10.23736/S0392-0488.20.06629-8.
<span class="bold">PMID: </span><a href="/pubmed/32618443" target="_blank">32618443</a></div>
<div class="nl"><a target="_blank" href="/pubmed/22570033">Pyodermitis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Empinotti JC,
Uyeda H,
Ruaro RT,
Galhardo AP,
Bonatto DC</span><br />
<span class="medgenPMjournal">An Bras Dermatol</span>
2012 Mar-Apr;87(2):277-84.
doi: 10.1590/s0365-05962012000200013.
<span class="bold">PMID: </span><a href="/pubmed/22570033" target="_blank">22570033</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Pyoderma%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (820)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/38423686">Pediatric Neutrophilic Dermatoses.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Moreno-Artero E,
Torrelo A</span><br />
<span class="medgenPMjournal">Dermatol Clin</span>
2024 Apr;42(2):267-283.
Epub 2024 Jan 20
doi: 10.1016/j.det.2023.12.005.
<span class="bold">PMID: </span><a href="/pubmed/38423686" target="_blank">38423686</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37673429">Pyoderma gangrenosum.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Yeung KCY,
O'Connor EM,
Hull PR</span><br />
<span class="medgenPMjournal">BMJ</span>
2023 Sep 6;382:e075863.
doi: 10.1136/bmj-2023-075863.
<span class="bold">PMID: </span><a href="/pubmed/37673429" target="_blank">37673429</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35606650">Pyoderma Gangrenosum: An Updated Literature Review on Established and Emerging Pharmacological Treatments.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Maronese CA,
Pimentel MA,
Li MM,
Genovese G,
Ortega-Loayza AG,
Marzano AV</span><br />
<span class="medgenPMjournal">Am J Clin Dermatol</span>
2022 Sep;23(5):615-634.
Epub 2022 May 24
doi: 10.1007/s40257-022-00699-8.
<span class="bold">PMID: </span><a href="/pubmed/35606650" target="_blank">35606650</a><a href="/pmc/articles/PMC9464730" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34910081">Pyoderma Gangrenosum.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Hou YL,
Lee CH</span><br />
<span class="medgenPMjournal">JAMA Dermatol</span>
2022 Feb 1;158(2):202.
doi: 10.1001/jamadermatol.2021.5001.
<span class="bold">PMID: </span><a href="/pubmed/34910081" target="_blank">34910081</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34538436">Pyoderma Gangrenosum: A Literature Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Barbe M,
Batra A,
Golding S,
Hammond O,
Higgins JC,
O'Connor A,
Vlahovic TC</span><br />
<span class="medgenPMjournal">Clin Podiatr Med Surg</span>
2021 Oct;38(4):577-588.
doi: 10.1016/j.cpm.2021.06.002.
<span class="bold">PMID: </span><a href="/pubmed/34538436" target="_blank">34538436</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Pyoderma%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1727)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/38423680">Treatment of Pyoderma Gangrenosum.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tan MG,
Tolkachjov SN</span><br />
<span class="medgenPMjournal">Dermatol Clin</span>
2024 Apr;42(2):183-192.
Epub 2023 Dec 29
doi: 10.1016/j.det.2023.12.002.
<span class="bold">PMID: </span><a href="/pubmed/38423680" target="_blank">38423680</a></div>
<div class="nl"><a target="_blank" href="/pubmed/38397117">The Pathophysiology and Treatment of Pyoderma Gangrenosum-Current Options and New Perspectives.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Łyko M,
Ryguła A,
Kowalski M,
Karska J,
Jankowska-Konsur A</span><br />
<span class="medgenPMjournal">Int J Mol Sci</span>
2024 Feb 19;25(4)
doi: 10.3390/ijms25042440.
<span class="bold">PMID: </span><a href="/pubmed/38397117" target="_blank">38397117</a><a href="/pmc/articles/PMC10889749" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29788368">Pyoderma Gangrenosum: A Review for the Gastroenterologist.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Plumptre I,
Knabel D,
Tomecki K</span><br />
<span class="medgenPMjournal">Inflamm Bowel Dis</span>
2018 Nov 29;24(12):2510-2517.
doi: 10.1093/ibd/izy174.
<span class="bold">PMID: </span><a href="/pubmed/29788368" target="_blank">29788368</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28629662">Pyoderma gangrenosum: Classic and emerging therapies.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Soto Vilches F,
Vera-Kellet C</span><br />
<span class="medgenPMjournal">Med Clin (Barc)</span>
2017 Sep 20;149(6):256-260.
Epub 2017 Jun 16
doi: 10.1016/j.medcli.2017.04.013.
<span class="bold">PMID: </span><a href="/pubmed/28629662" target="_blank">28629662</a></div>
<div class="nl"><a target="_blank" href="/pubmed/9001865">Pediatric dermatology.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Hartley AH,
Rabinowitz LG</span><br />
<span class="medgenPMjournal">Dermatol Clin</span>
1997 Jan;15(1):111-9.
doi: 10.1016/s0733-8635(05)70419-8.
<span class="bold">PMID: </span><a href="/pubmed/9001865" target="_blank">9001865</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Pyoderma%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1678)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/34538436">Pyoderma Gangrenosum: A Literature Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Barbe M,
Batra A,
Golding S,
Hammond O,
Higgins JC,
O'Connor A,
Vlahovic TC</span><br />
<span class="medgenPMjournal">Clin Podiatr Med Surg</span>
2021 Oct;38(4):577-588.
doi: 10.1016/j.cpm.2021.06.002.
<span class="bold">PMID: </span><a href="/pubmed/34538436" target="_blank">34538436</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34358489">Extraintestinal Manifestations of Inflammatory Bowel Disease: Current Concepts, Treatment, and Implications for Disease Management.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Rogler G,
Singh A,
Kavanaugh A,
Rubin DT</span><br />
<span class="medgenPMjournal">Gastroenterology</span>
2021 Oct;161(4):1118-1132.
Epub 2021 Aug 3
doi: 10.1053/j.gastro.2021.07.042.
<span class="bold">PMID: </span><a href="/pubmed/34358489" target="_blank">34358489</a><a href="/pmc/articles/PMC8564770" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/16325070">Pyoderma gangrenosum: uncommon presentations.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ahmadi S,
Powell FC</span><br />
<span class="medgenPMjournal">Clin Dermatol</span>
2005 Nov-Dec;23(6):612-20.
doi: 10.1016/j.clindermatol.2005.01.014.
<span class="bold">PMID: </span><a href="/pubmed/16325070" target="_blank">16325070</a></div>
<div class="nl"><a target="_blank" href="/pubmed/16253886">The global burden of group A streptococcal diseases.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Carapetis JR,
Steer AC,
Mulholland EK,
Weber M</span><br />
<span class="medgenPMjournal">Lancet Infect Dis</span>
2005 Nov;5(11):685-94.
doi: 10.1016/S1473-3099(05)70267-X.
<span class="bold">PMID: </span><a href="/pubmed/16253886" target="_blank">16253886</a></div>
<div class="nl"><a target="_blank" href="/pubmed/9001865">Pediatric dermatology.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Hartley AH,
Rabinowitz LG</span><br />
<span class="medgenPMjournal">Dermatol Clin</span>
1997 Jan;15(1):111-9.
doi: 10.1016/s0733-8635(05)70419-8.
<span class="bold">PMID: </span><a href="/pubmed/9001865" target="_blank">9001865</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Pyoderma%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (548)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/37610614">Pyoderma Gangrenosum: Treatment Options.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Dissemond J,
Marzano AV,
Hampton PJ,
Ortega-Loayza AG</span><br />
<span class="medgenPMjournal">Drugs</span>
2023 Sep;83(14):1255-1267.
Epub 2023 Aug 23
doi: 10.1007/s40265-023-01931-3.
<span class="bold">PMID: </span><a href="/pubmed/37610614" target="_blank">37610614</a><a href="/pmc/articles/PMC10511384" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34538436">Pyoderma Gangrenosum: A Literature Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Barbe M,
Batra A,
Golding S,
Hammond O,
Higgins JC,
O'Connor A,
Vlahovic TC</span><br />
<span class="medgenPMjournal">Clin Podiatr Med Surg</span>
2021 Oct;38(4):577-588.
doi: 10.1016/j.cpm.2021.06.002.
<span class="bold">PMID: </span><a href="/pubmed/34538436" target="_blank">34538436</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34358489">Extraintestinal Manifestations of Inflammatory Bowel Disease: Current Concepts, Treatment, and Implications for Disease Management.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Rogler G,
Singh A,
Kavanaugh A,
Rubin DT</span><br />
<span class="medgenPMjournal">Gastroenterology</span>
2021 Oct;161(4):1118-1132.
Epub 2021 Aug 3
doi: 10.1053/j.gastro.2021.07.042.
<span class="bold">PMID: </span><a href="/pubmed/34358489" target="_blank">34358489</a><a href="/pmc/articles/PMC8564770" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31927079">Perioperative management of pyoderma gangrenosum.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Haag CK,
Bacik L,
Latour E,
Morse DC,
Fett NM,
Ortega-Loayza AG</span><br />
<span class="medgenPMjournal">J Am Acad Dermatol</span>
2020 Aug;83(2):369-374.
Epub 2020 Jan 9
doi: 10.1016/j.jaad.2020.01.002.
<span class="bold">PMID: </span><a href="/pubmed/31927079" target="_blank">31927079</a></div>
<div class="nl"><a target="_blank" href="/pubmed/27230822">Hajj-associated infections.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Salmon-Rousseau A,
Piednoir E,
Cattoir V,
de La Blanchardière A</span><br />
<span class="medgenPMjournal">Med Mal Infect</span>
2016 Oct;46(7):346-354.
Epub 2016 May 24
doi: 10.1016/j.medmal.2016.04.002.
<span class="bold">PMID: </span><a href="/pubmed/27230822" target="_blank">27230822</a><a href="/pmc/articles/PMC7131558" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Pyoderma%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (408)</a></div></div>
</div>
<div class="portlet mgSection" id="ID_104">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">
<div class="nl"><a target="_blank" href="/pubmed/38906261">Investigating historic cases of pyoderma gangrenosum in myelodysplastic syndrome and chronic myelomonocytic leukemia for possible VEXAS syndrome: A systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Croitoru DO,
Huang RS,
McMullen EP,
Maazi M,
Piguet V</span><br />
<span class="medgenPMjournal">J Am Acad Dermatol</span>
2024 Oct;91(4):712-714.
Epub 2024 Jun 19
doi: 10.1016/j.jaad.2024.05.086.
<span class="bold">PMID: </span><a href="/pubmed/38906261" target="_blank">38906261</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35323998">Juvenile gangrenous vasculitis of the scrotum: systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Bazzi N,
Salloum A,
Chebl JA,
Hreibe W,
Bazzi M,
Fiani E,
Benedetto A,
Moussa M</span><br />
<span class="medgenPMjournal">Int J Dermatol</span>
2022 Nov;61(11):1364-1371.
Epub 2022 Mar 24
doi: 10.1111/ijd.16066.
<span class="bold">PMID: </span><a href="/pubmed/35323998" target="_blank">35323998</a></div>
<div class="nl"><a target="_blank" href="/pubmed/35293377">Onset of Pyoderma Gangrenosum in Patients on Biologic Therapies: A Systematic Review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Lytvyn Y,
Mufti A,
Maliyar K,
Sachdeva M,
Yeung J</span><br />
<span class="medgenPMjournal">Adv Skin Wound Care</span>
2022 Aug 1;35(8):454-460.
Epub 2022 Mar 16
doi: 10.1097/01.ASW.0000820252.96869.8e.
<span class="bold">PMID: </span><a href="/pubmed/35293377" target="_blank">35293377</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34942295">Clinical manifestations and treatment outcomes of pyoderma gangrenosum following rituximab exposure: A systematic review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Croitoru D,
Nathanielsz N,
Seigel K,
Elsawi R,
Sibbald C,
Alavi A,
Zipursky J,
Piguet V</span><br />
<span class="medgenPMjournal">J Am Acad Dermatol</span>
2022 Sep;87(3):655-656.
Epub 2021 Dec 20
doi: 10.1016/j.jaad.2021.12.028.
<span class="bold">PMID: </span><a href="/pubmed/34942295" target="_blank">34942295</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31927079">Perioperative management of pyoderma gangrenosum.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Haag CK,
Bacik L,
Latour E,
Morse DC,
Fett NM,
Ortega-Loayza AG</span><br />
<span class="medgenPMjournal">J Am Acad Dermatol</span>
2020 Aug;83(2):369-374.
Epub 2020 Jan 9
doi: 10.1016/j.jaad.2020.01.002.
<span class="bold">PMID: </span><a href="/pubmed/31927079" target="_blank">31927079</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Pyoderma%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (60)</a></div></div>
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