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<meta name="keywords" content="C0030185, breast paget disease, disease, mammary paget, disease, mammary paget's, mammary paget disease, mammary paget's disease, mammary pagets disease, neoplastic process, paget cell neoplasm, paget disease of breast, paget disease of the breast, paget disease, breast, paget disease, mammary, paget's disease of breast, paget's disease of the breast, paget's disease of the nipple, paget's disease of the nipple and areola, paget's disease, mammary, pagets disease, breast, pagets disease, mammary, pigmented mammary paget disease, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A malignant neoplasm in which there is infiltration of the skin overlying the breast by neoplastic large cells with abundant pale cytoplasm and large nuclei with prominent nucleoli (Paget cells). It is almost always associated with an intraductal or invasive ductal carcinoma of the breast. The clinical features include focal skin reddening, and eczema. Retraction of the nipple may sometimes occur." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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UID=18263
|
||
ConceptID=C0030185
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Mammary Paget disease</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>18263</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0030185</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Paget disease of the breast; Paget's disease of the nipple; Paget's disease, mammary</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Mammary Paget's disease (2985005); Paget disease, mammary (2985005); Paget's disease, mammary (2985005); Paget's disease of breast (2985005)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0002648" target="_blank">MONDO:0002648</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">A malignant neoplasm in which there is infiltration of the skin overlying the breast by neoplastic large cells with abundant pale cytoplasm and large nuclei with prominent nucleoli (Paget cells). It is almost always associated with an intraductal or invasive ductal carcinoma of the breast. The clinical features include focal skin reddening, and eczema. Retraction of the nipple may sometimes occur. [from <a title="NCI Thesaurus" href="http://ncit.nci.nih.gov" class="defSource" target="_blank">NCI</a>]</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Mammary Paget disease</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/4347" ref="tree=MeSH" title="MedGen record for Disease">Disease</a></span><ul><li><span class="TLline"><a href="/medgen/10294" ref="tree=MeSH" title="MedGen record for Neoplasm">Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/277963" ref="tree=MeSH" title="MedGen record for Epithelial neoplasm">Epithelial neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/2867" ref="tree=MeSH" title="MedGen record for Carcinoma">Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/122" ref="tree=MeSH" title="MedGen record for Adenocarcinoma">Adenocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/167809" ref="tree=MeSH" title="MedGen record for Breast adenocarcinoma">Breast adenocarcinoma</a></span><ul><li><span class="matched_ds">Mammary Paget disease</span><ul><li><span class="TLline"><a href="/medgen/569658" ref="tree=MeSH" title="MedGen record for Breast Paget Disease with Invasive Ductal Carcinoma">Breast Paget Disease with Invasive Ductal Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/311101" ref="tree=MeSH" title="MedGen record for Breast Paget Disease without Invasive Carcinoma">Breast Paget Disease without Invasive Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/124632" ref="tree=MeSH" title="MedGen record for Breast Paget Disease and Intraductal Carcinoma">Breast Paget Disease and Intraductal Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/352830" ref="tree=MeSH" title="MedGen record for Paget disease of the nipple">Paget disease of the nipple</a></span></li><li><span class="TLline"><a href="/medgen/1667595" ref="tree=MeSH" title="MedGen record for Recurrent Breast Paget Disease">Recurrent Breast Paget Disease</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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</div>
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<div class="portlet mgSection" id="ID_105">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/28614205">Spectrum of Changes in Anogenital Mammary-like Glands in Primary Extramammary (Anogenital) Paget Disease and Their Possible Role in the Pathogenesis of the Disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Konstantinova AM,
|
||
Spagnolo DV,
|
||
Stewart CJR,
|
||
Kacerovska D,
|
||
Shelekhova KV,
|
||
Plaza JA,
|
||
Suster S,
|
||
Bouda J,
|
||
Kyrpychova L,
|
||
Michal M,
|
||
Belousova IE,
|
||
Kerl K,
|
||
Kazakov DV</span><br />
|
||
<span class="medgenPMjournal">Am J Surg Pathol</span>
|
||
2017 Aug;41(8):1053-1058.
|
||
doi: 10.1097/PAS.0000000000000857.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28614205" target="_blank">28614205</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22mammary%20paget%20disease%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (1)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.nccn.org/professionals/physician_gls/pdf/breast.pdf" target="_blank">NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Breast Cancer, 2023</a></h3>
|
||
<h3 class="nl vspace"><a href="https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1419" target="_blank">Breast Cancer, NCCN Guidelines Version 4.2022</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36309195">Treatment of Mammary Paget Disease: A systematic review and meta-analysis of real-world data.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lin CW,
|
||
Chiang MH,
|
||
Tam KW</span><br />
|
||
<span class="medgenPMjournal">Int J Surg</span>
|
||
2022 Nov;107:106964.
|
||
Epub 2022 Oct 26
|
||
doi: 10.1016/j.ijsu.2022.106964.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36309195" target="_blank">36309195</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35263404">CK 8∕18: the key to differentiating intracutaneous lesions with pagetoid features.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tinca AC,
|
||
Cocuz IG,
|
||
Şincu MC,
|
||
Niculescu R,
|
||
Sabău AH,
|
||
Chiorean DM,
|
||
Morariu SH,
|
||
Turdean SG,
|
||
Cotoi OS</span><br />
|
||
<span class="medgenPMjournal">Rom J Morphol Embryol</span>
|
||
2021 Jul-Sep;62(3):757-763.
|
||
doi: 10.47162/RJME.62.3.13.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35263404" target="_blank">35263404</a><a href="/pmc/articles/PMC9019624" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33371071">Expression of lipoma preferred partner in mammary and extramammary Paget disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu Y,
|
||
Wang Y,
|
||
Qi R,
|
||
Mao X,
|
||
Jin F</span><br />
|
||
<span class="medgenPMjournal">Medicine (Baltimore)</span>
|
||
2020 Dec 18;99(51):e23443.
|
||
doi: 10.1097/MD.0000000000023443.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33371071" target="_blank">33371071</a><a href="/pmc/articles/PMC7748372" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31593076">Paget disease of the vulva an analysis of 24 cases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Loiacono RMR,
|
||
Traversi P,
|
||
Deliso MA,
|
||
Gargano G,
|
||
Kardhashi A,
|
||
Francescato R,
|
||
Loizzi V,
|
||
Spinelli M,
|
||
Lovascio S,
|
||
Fiorito M,
|
||
Resta L,
|
||
Popescu O,
|
||
Cicinelli E,
|
||
Cormio G</span><br />
|
||
<span class="medgenPMjournal">Medicine (Baltimore)</span>
|
||
2019 Oct;98(41):e17018.
|
||
doi: 10.1097/MD.0000000000017018.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31593076" target="_blank">31593076</a><a href="/pmc/articles/PMC6799860" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29943071">Expression of CD3, PD-L1 and CTLA-4 in mammary and extra-mammary Paget disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Karpathiou G,
|
||
Chauleur C,
|
||
Hathroubi S,
|
||
Habougit C,
|
||
Peoc'h M</span><br />
|
||
<span class="medgenPMjournal">Cancer Immunol Immunother</span>
|
||
2018 Aug;67(8):1297-1303.
|
||
Epub 2018 Jun 25
|
||
doi: 10.1007/s00262-018-2189-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29943071" target="_blank">29943071</a><a href="/pmc/articles/PMC11028266" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Mammary%20Paget%20disease%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (10)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38286721">Mammary Paget disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Brufau-Cochs M,
|
||
Guilarte-Cadavide C,
|
||
Ferrer-Artola M</span><br />
|
||
<span class="medgenPMjournal">Med Clin (Barc)</span>
|
||
2024 Jul 12;163(1):e2.
|
||
Epub 2024 Jan 28
|
||
doi: 10.1016/j.medcli.2023.11.022.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38286721" target="_blank">38286721</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31046904">Extramammary Paget disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">St Claire K,
|
||
Hoover A,
|
||
Ashack K,
|
||
Khachemoune A</span><br />
|
||
<span class="medgenPMjournal">Dermatol Online J</span>
|
||
2019 Apr 15;25(4)
|
||
<span class="bold">PMID: </span><a href="/pubmed/31046904" target="_blank">31046904</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26941231">Mimics of Mammary Paget Disease: A Rogues' Gallery.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hoda S,
|
||
Cheng E</span><br />
|
||
<span class="medgenPMjournal">Int J Surg Pathol</span>
|
||
2016 Sep;24(6):532-3.
|
||
Epub 2016 Mar 2
|
||
doi: 10.1177/1066896916635276.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26941231" target="_blank">26941231</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25773433">Pigmented mammary Paget disease mimicking cutaneous malignant melanoma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Brugués A,
|
||
Iranzo P,
|
||
Díaz A,
|
||
Peña A,
|
||
Estrach MT,
|
||
Carrera C</span><br />
|
||
<span class="medgenPMjournal">J Am Acad Dermatol</span>
|
||
2015 Apr;72(4):e97-8.
|
||
doi: 10.1016/j.jaad.2015.01.015.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25773433" target="_blank">25773433</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24005092">Mammary Paget disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Burke MJ,
|
||
Middleton TO</span><br />
|
||
<span class="medgenPMjournal">J Am Osteopath Assoc</span>
|
||
2013 Sep;113(9):712.
|
||
doi: 10.7556/jaoa.2013.038.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24005092" target="_blank">24005092</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Mammary%20Paget%20disease%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (34)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35939768">Phase II Study of Afatinib in Patients With Tumors With Human Epidermal Growth Factor Receptor 2-Activating Mutations: Results From the National Cancer Institute-Molecular Analysis for Therapy Choice ECOG-ACRIN Trial (EAY131) Subprotocol EAY131-B.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bedard PL,
|
||
Li S,
|
||
Wisinski KB,
|
||
Yang ES,
|
||
Limaye SA,
|
||
Mitchell EP,
|
||
Zwiebel JA,
|
||
Moscow JA,
|
||
Gray RJ,
|
||
Wang V,
|
||
McShane LM,
|
||
Rubinstein LV,
|
||
Patton DR,
|
||
Williams PM,
|
||
Hamilton SR,
|
||
Conley BA,
|
||
Arteaga CL,
|
||
Harris LN,
|
||
O'Dwyer PJ,
|
||
Chen AP,
|
||
Flaherty KT</span><br />
|
||
<span class="medgenPMjournal">JCO Precis Oncol</span>
|
||
2022 Jul;6:e2200165.
|
||
doi: 10.1200/PO.22.00165.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35939768" target="_blank">35939768</a><a href="/pmc/articles/PMC9384949" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33128407">Toker cell hyperplasia in Zuska disease: A tricky association.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Torre-Castro J,
|
||
Haya-Martínez L,
|
||
Ruffin-Vicente B,
|
||
Moya-Martínez C,
|
||
Núñez-Hipólito L,
|
||
Díaz de la Pinta J,
|
||
Cullen-Aravena D,
|
||
Jo-Velasco M,
|
||
Requena L</span><br />
|
||
<span class="medgenPMjournal">J Cutan Pathol</span>
|
||
2021 Jan;48(1):180-183.
|
||
Epub 2020 Nov 10
|
||
doi: 10.1111/cup.13908.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33128407" target="_blank">33128407</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20803209">Treatment of recurrent vulvar Paget disease with imiquimod cream: a case report and review of the literature.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tonguc E,
|
||
Güngor T,
|
||
Var T,
|
||
Ozat M,
|
||
Sahin I,
|
||
Sirvan L</span><br />
|
||
<span class="medgenPMjournal">Arch Gynecol Obstet</span>
|
||
2011 Jan;283(1):97-101.
|
||
Epub 2010 Aug 29
|
||
doi: 10.1007/s00404-010-1653-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20803209" target="_blank">20803209</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18369301">Complete resolution of Paget disease of the vulva with imiquimod cream.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hatch KD,
|
||
Davis JR</span><br />
|
||
<span class="medgenPMjournal">J Low Genit Tract Dis</span>
|
||
2008 Apr;12(2):90-4.
|
||
doi: 10.1097/LGT.0b013e31815a58a5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18369301" target="_blank">18369301</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Mammary%20Paget%20disease%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36309195">Treatment of Mammary Paget Disease: A systematic review and meta-analysis of real-world data.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lin CW,
|
||
Chiang MH,
|
||
Tam KW</span><br />
|
||
<span class="medgenPMjournal">Int J Surg</span>
|
||
2022 Nov;107:106964.
|
||
Epub 2022 Oct 26
|
||
doi: 10.1016/j.ijsu.2022.106964.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36309195" target="_blank">36309195</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35263404">CK 8∕18: the key to differentiating intracutaneous lesions with pagetoid features.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tinca AC,
|
||
Cocuz IG,
|
||
Şincu MC,
|
||
Niculescu R,
|
||
Sabău AH,
|
||
Chiorean DM,
|
||
Morariu SH,
|
||
Turdean SG,
|
||
Cotoi OS</span><br />
|
||
<span class="medgenPMjournal">Rom J Morphol Embryol</span>
|
||
2021 Jul-Sep;62(3):757-763.
|
||
doi: 10.47162/RJME.62.3.13.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35263404" target="_blank">35263404</a><a href="/pmc/articles/PMC9019624" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33592901">A strengthening the reporting of observational studies in epidemiology (STROBE): Are HE4 and CA 125 suitable to detect a Paget disease of the vulva?</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dellino M,
|
||
Gargano G,
|
||
Tinelli R,
|
||
Carriero C,
|
||
Minoia C,
|
||
Tetania S,
|
||
Silvestris E,
|
||
Loizzi V,
|
||
Paradiso A,
|
||
Casamassima P,
|
||
Tufaro A,
|
||
Cormio G,
|
||
Garrisi VM</span><br />
|
||
<span class="medgenPMjournal">Medicine (Baltimore)</span>
|
||
2021 Feb 5;100(5):e24485.
|
||
doi: 10.1097/MD.0000000000024485.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33592901" target="_blank">33592901</a><a href="/pmc/articles/PMC7870238" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31046904">Extramammary Paget disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">St Claire K,
|
||
Hoover A,
|
||
Ashack K,
|
||
Khachemoune A</span><br />
|
||
<span class="medgenPMjournal">Dermatol Online J</span>
|
||
2019 Apr 15;25(4)
|
||
<span class="bold">PMID: </span><a href="/pubmed/31046904" target="_blank">31046904</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29943071">Expression of CD3, PD-L1 and CTLA-4 in mammary and extra-mammary Paget disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Karpathiou G,
|
||
Chauleur C,
|
||
Hathroubi S,
|
||
Habougit C,
|
||
Peoc'h M</span><br />
|
||
<span class="medgenPMjournal">Cancer Immunol Immunother</span>
|
||
2018 Aug;67(8):1297-1303.
|
||
Epub 2018 Jun 25
|
||
doi: 10.1007/s00262-018-2189-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29943071" target="_blank">29943071</a><a href="/pmc/articles/PMC11028266" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Mammary%20Paget%20disease%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (15)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36309195">Treatment of Mammary Paget Disease: A systematic review and meta-analysis of real-world data.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lin CW,
|
||
Chiang MH,
|
||
Tam KW</span><br />
|
||
<span class="medgenPMjournal">Int J Surg</span>
|
||
2022 Nov;107:106964.
|
||
Epub 2022 Oct 26
|
||
doi: 10.1016/j.ijsu.2022.106964.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36309195" target="_blank">36309195</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33371071">Expression of lipoma preferred partner in mammary and extramammary Paget disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu Y,
|
||
Wang Y,
|
||
Qi R,
|
||
Mao X,
|
||
Jin F</span><br />
|
||
<span class="medgenPMjournal">Medicine (Baltimore)</span>
|
||
2020 Dec 18;99(51):e23443.
|
||
doi: 10.1097/MD.0000000000023443.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33371071" target="_blank">33371071</a><a href="/pmc/articles/PMC7748372" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32527320">Angiogenesis in mammary Paget disease: histopathological analyses of blood vessel density and angiogenic factors.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Akishima-Fukasawa Y,
|
||
Honma N,
|
||
Ogata H,
|
||
Akasaka Y,
|
||
Mikami T</span><br />
|
||
<span class="medgenPMjournal">Diagn Pathol</span>
|
||
2020 Jun 11;15(1):75.
|
||
doi: 10.1186/s13000-020-00988-y.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32527320" target="_blank">32527320</a><a href="/pmc/articles/PMC7288480" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31593076">Paget disease of the vulva an analysis of 24 cases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Loiacono RMR,
|
||
Traversi P,
|
||
Deliso MA,
|
||
Gargano G,
|
||
Kardhashi A,
|
||
Francescato R,
|
||
Loizzi V,
|
||
Spinelli M,
|
||
Lovascio S,
|
||
Fiorito M,
|
||
Resta L,
|
||
Popescu O,
|
||
Cicinelli E,
|
||
Cormio G</span><br />
|
||
<span class="medgenPMjournal">Medicine (Baltimore)</span>
|
||
2019 Oct;98(41):e17018.
|
||
doi: 10.1097/MD.0000000000017018.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31593076" target="_blank">31593076</a><a href="/pmc/articles/PMC6799860" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31046904">Extramammary Paget disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">St Claire K,
|
||
Hoover A,
|
||
Ashack K,
|
||
Khachemoune A</span><br />
|
||
<span class="medgenPMjournal">Dermatol Online J</span>
|
||
2019 Apr 15;25(4)
|
||
<span class="bold">PMID: </span><a href="/pubmed/31046904" target="_blank">31046904</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Mammary%20Paget%20disease%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (15)</a></div></div>
|
||
</div>
|
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|
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<div class="portlet mgSection" id="ID_104">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/36309195">Treatment of Mammary Paget Disease: A systematic review and meta-analysis of real-world data.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lin CW,
|
||
Chiang MH,
|
||
Tam KW</span><br />
|
||
<span class="medgenPMjournal">Int J Surg</span>
|
||
2022 Nov;107:106964.
|
||
Epub 2022 Oct 26
|
||
doi: 10.1016/j.ijsu.2022.106964.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36309195" target="_blank">36309195</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Mammary%20Paget%20disease%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1)</a></div></div>
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<h2 class="offscreen_noflow">Supplemental Content</h2>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22mammary%20paget%20disease%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Mammary%20Paget%20disease%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.nccn.org/professionals/physician_gls/pdf/breast.pdf">NCCN, 2023</a><div>NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) Breast Cancer, 2023</div></li><li><a target="_blank" href="https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1419">NCCN, 2023</a><div>Breast Cancer, NCCN Guidelines Version 4.2022</div></li></ul></div>
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