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<meta name="keywords" content="C5418756, metastatic malignant breast neoplasm, neoplastic process, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A malignant breast neoplasm that has metastasized to another anatomic site." /><meta name="robots" content="index,nofollow,noarchive" />
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<title>Metastatic Malignant Breast Neoplasm (Concept Id: C5418756)
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<!--
UID=1737420
ConceptID=C5418756
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Metastatic Malignant Breast Neoplasm</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1737420</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C5418756</a></dd><dt><span class="dotprefix"></span></dt><dd>Neoplastic Process</dd></dl></div></div></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">A malignant breast neoplasm that has metastasized to another anatomic site. [from <a title="NCI Thesaurus" href="http://ncit.nci.nih.gov" class="defSource" target="_blank">NCI</a>]</div>
</div>
<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Metastatic Malignant Breast Neoplasm</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/871338" ref="tree=MeSH" title="MedGen record for Abnormality of the breast">Abnormality of the breast</a></span><ul><li><span class="TLline"><a href="/medgen/1627648" ref="tree=MeSH" title="MedGen record for Abnormal breast morphology">Abnormal breast morphology</a></span><ul><li><span class="TLline"><a href="/medgen/264172" ref="tree=MeSH" title="MedGen record for Breast neoplasm">Breast neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/651" ref="tree=MeSH" title="MedGen record for Malignant tumor of breast">Malignant tumor of breast</a></span><ul><li><span class="matched_ds">Metastatic Malignant Breast Neoplasm</span><ul><li><span class="TLline"><a href="/medgen/1651514" ref="tree=MeSH" title="MedGen record for Metastatic Breast Carcinoma">Metastatic Breast Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1687643" ref="tree=MeSH" title="MedGen record for Advanced Breast Carcinoma">Advanced Breast Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1719544" ref="tree=MeSH" title="MedGen record for Advanced Breast Adenocarcinoma">Advanced Breast Adenocarcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/272383" ref="tree=MeSH" title="MedGen record for Breast Carcinoma Metastatic in the Bone">Breast Carcinoma Metastatic in the Bone</a></span><ul><li><span class="TLline"><a href="/medgen/1650310" ref="tree=MeSH" title="MedGen record for Breast Carcinoma Metastatic in the Spine">Breast Carcinoma Metastatic in the Spine</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1612003" ref="tree=MeSH" title="MedGen record for Breast Carcinoma Metastatic in the Central Nervous System">Breast Carcinoma Metastatic in the Central Nervous System</a></span><ul><li><span class="TLline"><a href="/medgen/234049" ref="tree=MeSH" title="MedGen record for Breast Carcinoma Metastatic in the Brain">Breast Carcinoma Metastatic in the Brain</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/272384" ref="tree=MeSH" title="MedGen record for Breast Carcinoma Metastatic in the Liver">Breast Carcinoma Metastatic in the Liver</a></span></li><li><span class="TLline"><a href="/medgen/231964" ref="tree=MeSH" title="MedGen record for Breast Carcinoma Metastatic in the Lung">Breast Carcinoma Metastatic in the Lung</a></span></li><li><span class="TLline"><a href="/medgen/1659340" ref="tree=MeSH" title="MedGen record for Breast Carcinoma Metastatic in the Lymph Nodes">Breast Carcinoma Metastatic in the Lymph Nodes</a></span></li><li><span class="TLline"><a href="/medgen/1703295" ref="tree=MeSH" title="MedGen record for Locally Advanced Breast Carcinoma">Locally Advanced Breast Carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1714254" ref="tree=MeSH" title="MedGen record for Locally Advanced Breast Adenocarcinoma">Locally Advanced Breast Adenocarcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1698790" ref="tree=MeSH" title="MedGen record for Locally Advanced Unresectable Breast Carcinoma">Locally Advanced Unresectable Breast Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1697431" ref="tree=MeSH" title="MedGen record for Metastatic BRCA-Associated Breast Carcinoma">Metastatic BRCA-Associated Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1712425" ref="tree=MeSH" title="MedGen record for Metastatic Breast Adenocarcinoma">Metastatic Breast Adenocarcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/395080" ref="tree=MeSH" title="MedGen record for Metastatic Breast Ductal Carcinoma">Metastatic Breast Ductal Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1793703" ref="tree=MeSH" title="MedGen record for Metastatic Breast Inflammatory Carcinoma">Metastatic Breast Inflammatory Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/437465" ref="tree=MeSH" title="MedGen record for Metastatic Breast Lobular Carcinoma">Metastatic Breast Lobular Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/233187" ref="tree=MeSH" title="MedGen record for Metastatic Breast Signet Ring Cell Carcinoma">Metastatic Breast Signet Ring Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1794008" ref="tree=MeSH" title="MedGen record for Metastatic HER2-Low Breast Carcinoma">Metastatic HER2-Low Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1709546" ref="tree=MeSH" title="MedGen record for Metastatic HER2-Negative Breast Carcinoma">Metastatic HER2-Negative Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1793161" ref="tree=MeSH" title="MedGen record for Metastatic HER2-Positive Breast Carcinoma">Metastatic HER2-Positive Breast Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1654154" ref="tree=MeSH" title="MedGen record for Metastatic Triple-Negative Breast Carcinoma">Metastatic Triple-Negative Breast Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/182595" ref="tree=MeSH" title="MedGen record for Metastatic Breast Carcinoma in the Skin">Metastatic Breast Carcinoma in the Skin</a></span></li><li><span class="TLline"><a href="/medgen/233188" ref="tree=MeSH" title="MedGen record for Metastatic Breast Squamous Cell Carcinoma">Metastatic Breast Squamous Cell Carcinoma</a></span></li><li><span class="TLline"><a href="/medgen/1792180" ref="tree=MeSH" title="MedGen record for Oligometastatic Breast Carcinoma">Oligometastatic Breast Carcinoma</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/1666248" ref="tree=MeSH" title="MedGen record for Metastatic Breast Neuroendocrine Neoplasm">Metastatic Breast Neuroendocrine Neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/233179" ref="tree=MeSH" title="MedGen record for Metastatic Breast Neuroendocrine Tumor G1">Metastatic Breast Neuroendocrine Tumor G1</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/35964548">Optimizing treatment management of trastuzumab deruxtecan in clinical practice of breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Rugo HS,
Bianchini G,
Cortes J,
Henning JW,
Untch M</span><br />
<span class="medgenPMjournal">ESMO Open</span>
2022 Aug;7(4):100553.
Epub 2022 Aug 11
doi: 10.1016/j.esmoop.2022.100553.
<span class="bold">PMID: </span><a href="/pubmed/35964548" target="_blank">35964548</a><a href="/pmc/articles/PMC9375150" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34678411">ESMO Clinical Practice Guideline for the diagnosis, staging and treatment of patients with metastatic breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gennari A,
André F,
Barrios CH,
Cortés J,
de Azambuja E,
DeMichele A,
Dent R,
Fenlon D,
Gligorov J,
Hurvitz SA,
Im SA,
Krug D,
Kunz WG,
Loi S,
Penault-Llorca F,
Ricke J,
Robson M,
Rugo HS,
Saura C,
Schmid P,
Singer CF,
Spanic T,
Tolaney SM,
Turner NC,
Curigliano G,
Loibl S,
Paluch-Shimon S,
Harbeck N;
ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org</span><br />
<span class="medgenPMjournal">Ann Oncol</span>
2021 Dec;32(12):1475-1495.
Epub 2021 Oct 19
doi: 10.1016/j.annonc.2021.09.019.
<span class="bold">PMID: </span><a href="/pubmed/34678411" target="_blank">34678411</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31894937">Lymphoma: Diagnosis and Treatment.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Lewis WD,
Lilly S,
Jones KL</span><br />
<span class="medgenPMjournal">Am Fam Physician</span>
2020 Jan 1;101(1):34-41.
<span class="bold">PMID: </span><a href="/pubmed/31894937" target="_blank">31894937</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(metastatic%20malignant%20breast%20neoplasm)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (4567)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/37943547">Global Stage Distribution of Breast Cancer at Diagnosis: A Systematic Review and Meta-Analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Benitez Fuentes JD,
Morgan E,
de Luna Aguilar A,
Mafra A,
Shah R,
Giusti F,
Vignat J,
Znaor A,
Musetti C,
Yip CH,
Van Eycken L,
Jedy-Agba E,
Piñeros M,
Soerjomataram I</span><br />
<span class="medgenPMjournal">JAMA Oncol</span>
2024 Jan 1;10(1):71-78.
doi: 10.1001/jamaoncol.2023.4837.
<span class="bold">PMID: </span><a href="/pubmed/37943547" target="_blank">37943547</a><a href="/pmc/articles/PMC10636649" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32399646">Molecular and cellular mechanisms underlying brain metastasis of breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Hosonaga M,
Saya H,
Arima Y</span><br />
<span class="medgenPMjournal">Cancer Metastasis Rev</span>
2020 Sep;39(3):711-720.
doi: 10.1007/s10555-020-09881-y.
<span class="bold">PMID: </span><a href="/pubmed/32399646" target="_blank">32399646</a><a href="/pmc/articles/PMC7497304" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31456182">Bone Metastasis of Breast Cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tahara RK,
Brewer TM,
Theriault RL,
Ueno NT</span><br />
<span class="medgenPMjournal">Adv Exp Med Biol</span>
2019;1152:105-129.
doi: 10.1007/978-3-030-20301-6_7.
<span class="bold">PMID: </span><a href="/pubmed/31456182" target="_blank">31456182</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30324552">Oligometastatic breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kwapisz D</span><br />
<span class="medgenPMjournal">Breast Cancer</span>
2019 Mar;26(2):138-146.
Epub 2018 Oct 15
doi: 10.1007/s12282-018-0921-1.
<span class="bold">PMID: </span><a href="/pubmed/30324552" target="_blank">30324552</a></div>
<div class="nl"><a target="_blank" href="/pubmed/20498394">Metastatic behavior of breast cancer subtypes.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kennecke H,
Yerushalmi R,
Woods R,
Cheang MC,
Voduc D,
Speers CH,
Nielsen TO,
Gelmon K</span><br />
<span class="medgenPMjournal">J Clin Oncol</span>
2010 Jul 10;28(20):3271-7.
Epub 2010 May 24
doi: 10.1200/JCO.2009.25.9820.
<span class="bold">PMID: </span><a href="/pubmed/20498394" target="_blank">20498394</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Metastatic%20Malignant%20Breast%20Neoplasm%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (23017)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/37943547">Global Stage Distribution of Breast Cancer at Diagnosis: A Systematic Review and Meta-Analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Benitez Fuentes JD,
Morgan E,
de Luna Aguilar A,
Mafra A,
Shah R,
Giusti F,
Vignat J,
Znaor A,
Musetti C,
Yip CH,
Van Eycken L,
Jedy-Agba E,
Piñeros M,
Soerjomataram I</span><br />
<span class="medgenPMjournal">JAMA Oncol</span>
2024 Jan 1;10(1):71-78.
doi: 10.1001/jamaoncol.2023.4837.
<span class="bold">PMID: </span><a href="/pubmed/37943547" target="_blank">37943547</a><a href="/pmc/articles/PMC10636649" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37958607">Organ-Specificity of Breast Cancer Metastasis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ibragimova MK,
Tsyganov MM,
Kravtsova EA,
Tsydenova IA,
Litviakov NV</span><br />
<span class="medgenPMjournal">Int J Mol Sci</span>
2023 Oct 26;24(21)
doi: 10.3390/ijms242115625.
<span class="bold">PMID: </span><a href="/pubmed/37958607" target="_blank">37958607</a><a href="/pmc/articles/PMC10650169" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37611540">Metastatic and Malignant Phyllodes Tumors of the Breast: An Update for Current Management.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Goodwin B,
Oyinlola AF,
Palhang M,
Lehman D,
Platoff R,
Atabek U,
Spitz F,
Hong Y</span><br />
<span class="medgenPMjournal">Am Surg</span>
2023 Dec;89(12):6190-6196.
Epub 2023 Aug 23
doi: 10.1177/00031348231198114.
<span class="bold">PMID: </span><a href="/pubmed/37611540" target="_blank">37611540</a></div>
<div class="nl"><a target="_blank" href="/pubmed/21755793">Treatment and care of patients with metastatic breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Beaumont T,
Leadbeater M</span><br />
<span class="medgenPMjournal">Nurs Stand</span>
2011 Jun 8-14;25(40):49-56.
doi: 10.7748/ns2011.06.25.40.49.c8566.
<span class="bold">PMID: </span><a href="/pubmed/21755793" target="_blank">21755793</a></div>
<div class="nl"><a target="_blank" href="/pubmed/18396194">Introduction: role of surgery in the diagnosis and management of metastatic cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Berger AC</span><br />
<span class="medgenPMjournal">Semin Oncol</span>
2008 Apr;35(2):98-9.
doi: 10.1053/j.seminoncol.2008.01.002.
<span class="bold">PMID: </span><a href="/pubmed/18396194" target="_blank">18396194</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Metastatic%20Malignant%20Breast%20Neoplasm%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (20136)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/30324552">Oligometastatic breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kwapisz D</span><br />
<span class="medgenPMjournal">Breast Cancer</span>
2019 Mar;26(2):138-146.
Epub 2018 Oct 15
doi: 10.1007/s12282-018-0921-1.
<span class="bold">PMID: </span><a href="/pubmed/30324552" target="_blank">30324552</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29542106">Breast surgery for metastatic breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tosello G,
Torloni MR,
Mota BS,
Neeman T,
Riera R</span><br />
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
2018 Mar 15;3(3):CD011276.
doi: 10.1002/14651858.CD011276.pub2.
<span class="bold">PMID: </span><a href="/pubmed/29542106" target="_blank">29542106</a><a href="/pmc/articles/PMC6494198" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28097656">Palliation and breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Yip CH</span><br />
<span class="medgenPMjournal">J Surg Oncol</span>
2017 Apr;115(5):538-543.
Epub 2017 Jan 18
doi: 10.1002/jso.24560.
<span class="bold">PMID: </span><a href="/pubmed/28097656" target="_blank">28097656</a></div>
<div class="nl"><a target="_blank" href="/pubmed/8312119">Breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Bailey HH,
Carbone PP</span><br />
<span class="medgenPMjournal">Cancer Chemother Biol Response Modif</span>
1993;14:557-76.
<span class="bold">PMID: </span><a href="/pubmed/8312119" target="_blank">8312119</a></div>
<div class="nl"><a target="_blank" href="/pubmed/8305549">Metastatic breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Rubens RD</span><br />
<span class="medgenPMjournal">Curr Opin Oncol</span>
1993 Nov;5(6):991-5.
doi: 10.1097/00001622-199311000-00007.
<span class="bold">PMID: </span><a href="/pubmed/8305549" target="_blank">8305549</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Metastatic%20Malignant%20Breast%20Neoplasm%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (24064)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/33581774">Pyrotinib plus capecitabine versus lapatinib plus capecitabine for the treatment of HER2-positive metastatic breast cancer (PHOEBE): a multicentre, open-label, randomised, controlled, phase 3 trial.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Xu B,
Yan M,
Ma F,
Hu X,
Feng J,
Ouyang Q,
Tong Z,
Li H,
Zhang Q,
Sun T,
Wang X,
Yin Y,
Cheng Y,
Li W,
Gu Y,
Chen Q,
Liu J,
Cheng J,
Geng C,
Qin S,
Wang S,
Lu J,
Shen K,
Liu Q,
Wang X,
Wang H,
Luo T,
Yang J,
Wu Y,
Yu Z,
Zhu X,
Chen C,
Zou J;
PHOEBE Investigators</span><br />
<span class="medgenPMjournal">Lancet Oncol</span>
2021 Mar;22(3):351-360.
Epub 2021 Feb 11
doi: 10.1016/S1470-2045(20)30702-6.
<span class="bold">PMID: </span><a href="/pubmed/33581774" target="_blank">33581774</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29781189">Esthesioneuroblastoma metastatic to the breast.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Moalla S,
Gharbi S,
Mbarki C,
Chennoufi H,
Melliti S,
Mezghani Boussetta S</span><br />
<span class="medgenPMjournal">Breast J</span>
2018 Sep;24(5):836-837.
Epub 2018 May 20
doi: 10.1111/tbj.13054.
<span class="bold">PMID: </span><a href="/pubmed/29781189" target="_blank">29781189</a></div>
<div class="nl"><a target="_blank" href="/pubmed/20498394">Metastatic behavior of breast cancer subtypes.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kennecke H,
Yerushalmi R,
Woods R,
Cheang MC,
Voduc D,
Speers CH,
Nielsen TO,
Gelmon K</span><br />
<span class="medgenPMjournal">J Clin Oncol</span>
2010 Jul 10;28(20):3271-7.
Epub 2010 May 24
doi: 10.1200/JCO.2009.25.9820.
<span class="bold">PMID: </span><a href="/pubmed/20498394" target="_blank">20498394</a></div>
<div class="nl"><a target="_blank" href="/pubmed/1444787">Pulmonary resection for metastatic breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Staren ED,
Salerno C,
Rongione A,
Witt TR,
Faber LP</span><br />
<span class="medgenPMjournal">Arch Surg</span>
1992 Nov;127(11):1282-4.
doi: 10.1001/archsurg.1992.01420110024006.
<span class="bold">PMID: </span><a href="/pubmed/1444787" target="_blank">1444787</a></div>
<div class="nl"><a target="_blank" href="/pubmed/1291890">The Neuro-Oncology Register.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Lassouw GM,
Twijnstra A,
Schouten LJ,
van de Pol M</span><br />
<span class="medgenPMjournal">Neuroepidemiology</span>
1992;11(4-6):261-6.
doi: 10.1159/000110939.
<span class="bold">PMID: </span><a href="/pubmed/1291890" target="_blank">1291890</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Metastatic%20Malignant%20Breast%20Neoplasm%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (21577)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/37541274">Artificial intelligence-supported screen reading versus standard double reading in the Mammography Screening with Artificial Intelligence trial (MASAI): a clinical safety analysis of a randomised, controlled, non-inferiority, single-blinded, screening accuracy study.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Lång K,
Josefsson V,
Larsson AM,
Larsson S,
Högberg C,
Sartor H,
Hofvind S,
Andersson I,
Rosso A</span><br />
<span class="medgenPMjournal">Lancet Oncol</span>
2023 Aug;24(8):936-944.
doi: 10.1016/S1470-2045(23)00298-X.
<span class="bold">PMID: </span><a href="/pubmed/37541274" target="_blank">37541274</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34000244">Updated recommendations regarding the management of older patients with breast cancer: a joint paper from the European Society of Breast Cancer Specialists (EUSOMA) and the International Society of Geriatric Oncology (SIOG).</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Biganzoli L,
Battisti NML,
Wildiers H,
McCartney A,
Colloca G,
Kunkler IH,
Cardoso MJ,
Cheung KL,
de Glas NA,
Trimboli RM,
Korc-Grodzicki B,
Soto-Perez-de-Celis E,
Ponti A,
Tsang J,
Marotti L,
Benn K,
Aapro MS,
Brain EGC</span><br />
<span class="medgenPMjournal">Lancet Oncol</span>
2021 Jul;22(7):e327-e340.
Epub 2021 May 14
doi: 10.1016/S1470-2045(20)30741-5.
<span class="bold">PMID: </span><a href="/pubmed/34000244" target="_blank">34000244</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30100082">Imaging Tumor Proliferation in Breast Cancer: Current Update on Predictive Imaging Biomarkers.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Elmi A,
McDonald ES,
Mankoff D</span><br />
<span class="medgenPMjournal">PET Clin</span>
2018 Jul;13(3):445-457.
doi: 10.1016/j.cpet.2018.02.007.
<span class="bold">PMID: </span><a href="/pubmed/30100082" target="_blank">30100082</a><a href="/pmc/articles/PMC6092945" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/26339424">Clinicopathological classification and traditional prognostic indicators of breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Li J,
Chen Z,
Su K,
Zeng J</span><br />
<span class="medgenPMjournal">Int J Clin Exp Pathol</span>
2015;8(7):8500-5.
Epub 2015 Jul 1
<span class="bold">PMID: </span><a href="/pubmed/26339424" target="_blank">26339424</a><a href="/pmc/articles/PMC4555752" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/17706530">Diagnosis of recurrent and metastatic disease using f-18 fluorodeoxyglucose-positron emission tomography in breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Eubank WB</span><br />
<span class="medgenPMjournal">Radiol Clin North Am</span>
2007 Jul;45(4):659-67, vi.
doi: 10.1016/j.rcl.2007.05.005.
<span class="bold">PMID: </span><a href="/pubmed/17706530" target="_blank">17706530</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Metastatic%20Malignant%20Breast%20Neoplasm%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (18391)</a></div></div>
</div>
<div class="portlet mgSection" id="ID_104">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">
<div class="nl"><a target="_blank" href="/pubmed/37943547">Global Stage Distribution of Breast Cancer at Diagnosis: A Systematic Review and Meta-Analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Benitez Fuentes JD,
Morgan E,
de Luna Aguilar A,
Mafra A,
Shah R,
Giusti F,
Vignat J,
Znaor A,
Musetti C,
Yip CH,
Van Eycken L,
Jedy-Agba E,
Piñeros M,
Soerjomataram I</span><br />
<span class="medgenPMjournal">JAMA Oncol</span>
2024 Jan 1;10(1):71-78.
doi: 10.1001/jamaoncol.2023.4837.
<span class="bold">PMID: </span><a href="/pubmed/37943547" target="_blank">37943547</a><a href="/pmc/articles/PMC10636649" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37336117">Safety profile of cyclin-dependent kinase (CDK) 4/6 inhibitors with concurrent radiation therapy: A systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Becherini C,
Visani L,
Caini S,
Bhattacharya IS,
Kirby AM,
Nader Marta G,
Morgan G,
Salvestrini V,
Coles CE,
Cortes J,
Curigliano G,
de Azambuja E,
Harbeck N,
Isacke CM,
Kaidar-Person O,
Marangoni E,
Offersen B,
Rugo HS,
Morandi A,
Lambertini M,
Poortmans P,
Livi L,
Meattini I</span><br />
<span class="medgenPMjournal">Cancer Treat Rev</span>
2023 Sep;119:102586.
Epub 2023 Jun 15
doi: 10.1016/j.ctrv.2023.102586.
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Dayao Z,
Elias A,
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McShane LM,
Moy B,
Park BH,
Shanahan KM,
Sharma P,
Shatsky R,
Stringer-Reasor E,
Telli M,
Turner NC,
DeMichele A</span><br />
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2022 Sep 20;40(27):3205-3221.
Epub 2022 Jun 27
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Barton DL,
Dorris A,
Fallowfield LJ,
Jain D,
Johnston SRD,
Korde LA,
Litton JK,
Macrae ER,
Peterson LL,
Vikas P,
Yung RL,
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<span class="medgenPMjournal">J Clin Oncol</span>
2021 Dec 10;39(35):3959-3977.
Epub 2021 Jul 29
doi: 10.1200/JCO.21.01392.
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<div class="nl"><a target="_blank" href="/pubmed/29542106">Breast surgery for metastatic breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tosello G,
Torloni MR,
Mota BS,
Neeman T,
Riera R</span><br />
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
2018 Mar 15;3(3):CD011276.
doi: 10.1002/14651858.CD011276.pub2.
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Metastatic%20Malignant%20Breast%20Neoplasm%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (916)</a></div></div>
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