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<meta name="keywords" content="CN208474, difficulty getting a full erection, difficulty getting an erection, finding, impotence, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="Inability to develop or maintain an erection of the penis." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
UID=1720680
ConceptID=CN208474
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Impotence</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1720680</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier assigned by MedGen (starting with CN) for terms&#10;that cannot be identified in NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">CN208474</a></dd><dt><span class="dotprefix"></span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
<td>Difficulty getting a full erection; Difficulty getting an erection</td></tr>
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0000802">HP:0000802</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">Inability to develop or maintain an erection of the penis. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
</div>
<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Impotence</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/19974" ref="tree=MeSH" title="MedGen record for Clinical finding">Clinical finding</a></span><ul><li><span class="TLline"><a href="/medgen/761917" ref="tree=MeSH" title="MedGen record for Sign or Symptom">Sign or Symptom</a></span><ul><li><span class="TLline"><a href="/medgen/234308" ref="tree=MeSH" title="MedGen record for Genitourinary Signs and Symptoms">Genitourinary Signs and Symptoms</a></span><ul><li><span class="TLline"><a href="/medgen/76197" ref="tree=MeSH" title="MedGen record for Sexual Dysfunction and Infertility">Sexual Dysfunction and Infertility</a></span><ul><li><span class="TLline"><a href="/medgen/154293" ref="tree=MeSH" title="MedGen record for Decreased sexual function">Decreased sexual function</a></span><ul><li><span class="TLline"><a href="/medgen/66879" ref="tree=MeSH" title="MedGen record for Erectile dysfunction">Erectile dysfunction</a></span><ul><li><span class="matched_ds">Impotence</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_112">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln clinfeat">
<div class="divPopper rprt" id="rdis_11313"><div><strong>Sandhoff disease</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>11313</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0036161</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Sandhoff disease comprises a phenotypic continuum encompassing acute infantile, subacute juvenile, and late-onset disease. Although classification into these phenotypes is somewhat arbitrary, it is helpful in understanding the variation observed in the timing of disease onset, presenting manifestations, rate of progression, and life span. Acute infantile Sandhoff disease (onset age &lt;6 months). Infants are generally normal at birth followed by progressive weakness and slowing of developmental progress, then developmental regression and severe neurologic impairment. Seizures are common. Death usually occurs between ages two and three years. Subacute juvenile Sandhoff disease (onset age 2-5 years). After attaining normal developmental milestones, developmental progress slows, followed by developmental regression and neurologic impairment (abnormal gait, dysarthria, and cognitive decline). Death (usually from aspiration) typically occurs in the early to late teens. Late-onset Sandhoff disease (onset older teen years or young adulthood). Nearly normal psychomotor development is followed by a range of neurologic findings (e.g., weakness, spasticity, dysarthria, and deficits in cerebellar function) and psychiatric findings (e.g., deficits in executive function and memory). Life expectancy is not necessarily decreased.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/11313">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_57667"><div><strong>Adrenoleukodystrophy</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>57667</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C0162309</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">X-linked adrenoleukodystrophy (X-ALD) involves the central or peripheral nervous system and the adrenal cortex. The nervous system and adrenal glands are involved independently; thus, an affected male may be diagnosed with cerebral adrenoleukodystrophy (CALD), adrenomyeloneuropathy (AMN), and/or primary adrenocortical insufficiency. CALD is characterized by progressive behavioral, cognitive, and neurologic deficits; onset of symptoms ranges from childhood (typically ages 4 to 8 years) to adolescence (ages 11 to 21 years) and adulthood. AMN is characterized by leg weakness, spasticity, clumsy gait, pain, and bladder and bowel dysfunction; onset is typically in the 20s and 30s. Onset of primary adrenocortical insufficiency ranges from age two years to adulthood (most commonly by age 7.5 years). Heterozygous females are not at increased risk to develop CALD, but are at increased risk to develop AMN and primary adrenocortical insufficiency with increasing age.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/57667">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_333403"><div><strong>Fragile X-associated tremor/ataxia syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>333403</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1839780</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">FMR1 disorders include fragile X syndrome (FXS), fragile X-associated tremor/ataxia syndrome (FXTAS), and fragile X-associated primary ovarian insufficiency (FXPOI). Fragile X syndrome occurs in individuals with an FMR1 full mutation or other loss-of-function variant and is nearly always characterized in affected males by developmental delay and intellectual disability along with a variety of behavioral issues. Autism spectrum disorder is present in 50%-70% of individuals with FXS. Affected males may have characteristic craniofacial features (which become more obvious with age) and medical problems including hypotonia, gastroesophageal reflux, strabismus, seizures, sleep disorders, joint laxity, pes planus, scoliosis, and recurrent otitis media. Adults may have mitral valve prolapse or aortic root dilatation. The physical and behavioral features seen in males with FXS have been reported in females heterozygous for the FMR1 full mutation, but with lower frequency and milder involvement. FXTAS occurs in individuals who have an FMR1 premutation and is characterized by late-onset, progressive cerebellar ataxia and intention tremor followed by cognitive impairment. Psychiatric disorders are common. Age of onset is typically between 60 and 65 years and is more common among males who are hemizygous for the premutation (40%) than among females who are heterozygous for the premutation (16%-20%). FXPOI, defined as hypergonadotropic hypogonadism before age 40 years, has been observed in 20% of women who carry a premutation allele compared to 1% in the general population.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/333403">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_330880"><div><strong>Hereditary sensory and autonomic neuropathy type 1B</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>330880</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1842586</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">The hereditary sensory and autonomic neuropathies (HSAN), which are also referred to as hereditary sensory neuropathies (HSN) in the absence of significant autonomic features, are a genetically and clinically heterogeneous group of disorders associated with sensory dysfunction. For a discussion of genetic heterogeneity of HSAN, see HSAN1A (162400).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/330880">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_340044"><div><strong>Hemochromatosis type 4</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>340044</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1853733</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Hemochromatosis type 4 (HFE4) is a dominantly inherited iron overload disorder with heterogeneous phenotypic manifestations that can be classified into 2 groups. One group is characterized by an early rise in ferritin (see 134790) levels with low to normal transferrin (190000) saturation and iron accumulation predominantly in macrophages. The other group is similar to classical hemochromatosis, with high transferrin saturation and prominent parenchymal iron loading (summary by De Domenico et al., 2005).&#13; For general background information and a discussion of genetic heterogeneity of hereditary hemochromatosis, see 235200.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/340044">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_388114"><div><strong>Hemochromatosis type 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>388114</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information."><span class="highlight" style="background-color:">C1858664</span></a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">TFR2-related hemochromatosis (TFR2-HC) is characterized by increased intestinal iron absorption resulting in iron accumulation in the liver, heart, pancreas, and endocrine organs. Age of onset is earlier than in HFE-related hemochromatosis. The majority of individuals present with signs and symptoms of iron overload in the third decade (e.g., weakness, fatigue, abdominal pain, hepatomegaly, arthritis, arthralgia, and progressive increase in skin pigmentation). Others present as young adults with nonspecific symptoms and abnormal serum iron studies or as adults with abnormal serum iron studies and signs of organ involvement including cirrhosis, diabetes mellitus, arthropathy, hypogonadism, cardiomyopathy, and increase in skin pigmentation.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/388114">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_356995"><div><strong>Adult-onset autosomal dominant demyelinating leukodystrophy</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>356995</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C1868512</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">LMNB1-related autosomal dominant leukodystrophy (ADLD) is a slowly progressive disorder of central nervous system white matter characterized by onset of autonomic dysfunction in the fourth to fifth decade, followed by pyramidal and cerebellar abnormalities resulting in spasticity, ataxia, and tremor. Autonomic dysfunction can include bladder dysfunction, constipation, postural hypotension, erectile dysfunction, and (less often) impaired sweating. Pyramidal signs are often more prominent in the lower extremities (e.g., spastic weakness, hypertonia, clonus, brisk deep tendon reflexes, and bilateral Babinski signs). Cerebellar signs typically appear at the same time as the pyramidal signs and include gait ataxia, dysdiadochokinesia, intention tremor, dysmetria, and nystagmus. Many individuals have sensory deficits starting in the lower limbs. Pseudobulbar palsy with dysarthria, dysphagia, and forced crying and laughing may appear in the seventh or eighth decade. Although cognitive function is usually preserved or only mildly impaired early in the disease course, dementia and psychiatric manifestations can occur as late manifestations. Affected individuals may survive for decades after onset.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/356995">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_414031"><div><strong>Amyloidosis, hereditary systemic 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>414031</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C2751492</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Hereditary transthyretin amyloidosis (ATTRv amyloidosis) is characterized by a slowly progressive peripheral sensorimotor and/or autonomic neuropathy. Amyloidosis can involve the heart, central nervous system (CNS), eyes, and kidneys. The disease usually begins in the third to fifth decade in persons from endemic foci in Portugal and Japan; onset is later in persons from other areas. Typically, sensory neuropathy starts in the lower extremities with paresthesia and hypesthesia of the feet, followed within a few years by motor neuropathy. In some persons, particularly those with early-onset disease, autonomic neuropathy is the first manifestation of the condition; findings can include orthostatic hypotension, constipation alternating with diarrhea, attacks of nausea and vomiting, delayed gastric emptying, sexual impotence, anhidrosis, and urinary retention or incontinence. Cardiac amyloidosis is mainly characterized by progressive restrictive cardiomyopathy. Individuals with leptomeningeal amyloidosis may have the following CNS findings: dementia, psychosis, visual impairment, headache, seizures, motor paresis, ataxia, myelopathy, hydrocephalus, or intracranial hemorrhage. Ocular involvement includes vitreous opacity, glaucoma, dry eye, and ocular amyloid angiopathy. Mild-to-severe kidney disease can develop.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/414031">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_854011"><div><strong>Hemochromatosis type 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>854011</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C3469186</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">HFE-related hemochromatosis (HFE HC) is characterized by increased intestinal iron absorption and increased recycling of iron derived from senescent red blood cells. The phenotypic spectrum of HFE HC includes clinical HFE HC (increased serum ferritin and transferrin saturation and end-organ damage secondary to iron overload), biochemical HFE HC (increased serum ferritin and transferrin saturation without end-organ damage), and non-penetrant HFE HC (neither clinical manifestations of HFE HC nor iron overload are present, although elevated transferrin saturation may occur). Clinical HFE HC is characterized by excessive iron in the liver, pancreas, heart, skin, joints, and anterior pituitary gland. In untreated individuals, early manifestations include weakness, chronic fatigue, abdominal pain, weight loss, arthralgias, and diabetes mellitus. Individuals with HFE HC have an increased risk of cirrhosis when their serum ferritin is higher than 1,000 µg/L. Other findings of severe iron overload include hypogonadism, congestive heart failure, arrhythmias, and progressive increase in skin pigmentation. Clinical HFE HC is more common in males than females.</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/854011">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_811503"><div><strong>Multiple system atrophy 1, susceptibility to</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>811503</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C3714927</a></dd><dt><span class="dotprefix"></span></dt><dd>Finding</dd></dl></div></div></div>
<div class="spaceAbove">Multiple system atrophy (MSA) is a distinct clinicopathologic entity that manifests as a progressive adult-onset neurodegenerative disorder causing parkinsonism, cerebellar ataxia, and autonomic, urogenital, and pyramidal dysfunction in various combinations. Two main subtypes are recognized: 'subtype C,' characterized predominantly by cerebellar ataxia, and 'subtype P,' characterized predominantly by parkinsonism. MSA is characterized pathologically by the degeneration of striatonigral and olivopontocerebellar structures and glial cytoplasmic inclusions (GCIs) that consist of abnormally phosphorylated alpha-synuclein (SNCA; 163890) or tau (MAPT; 157140) (Gilman et al., 1998; Gilman et al., 2008; Scholz et al., 2009). 'Subtype C' of MSA has been reported to be more prevalent than 'subtype P' in the Japanese population (65-67% vs 33-35%), whereas 'subtype P' has been reported to be more prevalent than 'subtype C' in Europe (63% vs 34%) and North America (60% vs 13%, with 27% of cases unclassified) (summary by The Multiple-System Atrophy Research Collaboration, 2013).&#13; MSA is similar clinically and pathologically to Parkinson disease (PD; 168600) and Lewy body dementia (127750). See also PARK1 (168601), which is specifically caused by mutation in the SNCA gene.&#13; Pure autonomic failure manifests as orthostatic hypotension and other autonomic abnormalities without other neurologic involvement. Although there is some phenotypic overlap, the relationship of pure autonomic failure to MSA is unclear (Vanderhaeghen et al., 1970; Schatz, 1996).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/811503">Condition Record</a></div></div>
<div class="divPopper rprt" id="rdis_816733"><div><strong>Moyamoya disease with early-onset achalasia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>816733</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C3810403</a></dd><dt><span class="dotprefix"></span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
<div class="spaceAbove">Moyamoya disease-6 (MYMY6) is a progressive vasculopathy characterized by occlusion of the terminal portion of the internal carotid arteries and its branches, and the formation of compensatory neovascularization and the moyamoya, or 'puff of smoke,' appearance of these vessels on angiogram. Affected individuals may present with ischemic strokes, intracerebral hemorrhage, or transient ischemic attacks. Patients with MYMY6 usually present early in life with achalasia. Hypertension and Raynaud phenomenon may be associated features (summary by Wallace et al., 2016; Herve et al., 2014).&#13; For a general phenotypic description and a discussion of genetic heterogeneity of moyamoya disease, see MYMY1 (252350).</div>
<div class="spaceAbove nowrap">See: <a href="/medgen/816733">Condition Record</a></div></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_57667" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Adrenoleukodystrophy</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_356995" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Adult-onset autosomal dominant demyelinating leukodystrophy</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_414031" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Amyloidosis, hereditary systemic 1</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_333403" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Fragile X-associated tremor/ataxia syndrome</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_854011" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hemochromatosis type 1</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (11)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_388114" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hemochromatosis type 3</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_340044" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hemochromatosis type 4</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_330880" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hereditary sensory and autonomic neuropathy type 1B</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_816733" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Moyamoya disease with early-onset achalasia</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_811503" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Multiple system atrophy 1, susceptibility to</a></div>
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_11313" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Sandhoff disease</a></div></span></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/8479008">Venous impotence: pathophysiology, diagnosis and treatment.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Wespes E,
Schulman C</span><br />
<span class="medgenPMjournal">J Urol</span>
1993 May;149(5 Pt 2):1238-45.
doi: 10.1016/s0022-5347(17)36358-9.
<span class="bold">PMID: </span><a href="/pubmed/8479008" target="_blank">8479008</a></div>
<div class="nl"><a target="_blank" href="/pubmed/8173631">Consensus development conference statement. National Institutes of Health. Impotence. December 7-9, 1992.</a></div>
<div class="portlet_content ln"><span class="medgenPMjournal">Int J Impot Res</span>
1993 Dec;5(4):181-284.
<span class="bold">PMID: </span><a href="/pubmed/8173631" target="_blank">8173631</a></div>
<div class="nl"><a target="_blank" href="/pubmed/7266447">Impotence--evaluation and treatment.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Godec CJ,
Cass AS</span><br />
<span class="medgenPMjournal">Minn Med</span>
1981 Jul;64(7):405-9.
<span class="bold">PMID: </span><a href="/pubmed/7266447" target="_blank">7266447</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22impotence%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (505)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/33227246">Vasculogenic Erectile Dysfunction: The Impact of Diet and Lifestyle.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ostfeld RJ,
Allen KE,
Aspry K,
Brandt EJ,
Spitz A,
Liberman J,
Belardo D,
O'Keefe JH,
Aggarwal M,
Miller M,
Batiste C,
Kopecky S,
White B,
Shah N,
Hawamdeh H,
Batts T,
Blankstein R,
Reddy K,
Ornish D,
Freeman AM</span><br />
<span class="medgenPMjournal">Am J Med</span>
2021 Mar;134(3):310-316.
Epub 2020 Nov 20
doi: 10.1016/j.amjmed.2020.09.033.
<span class="bold">PMID: </span><a href="/pubmed/33227246" target="_blank">33227246</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28486869">Erectile dysfunction - overview from a cardiovascular perspective.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Baumann F,
Hehli D,
Makaloski V,
Schumacher M,
Schönhofen H,
Diehm N</span><br />
<span class="medgenPMjournal">Vasa</span>
2017 Aug;46(5):347-353.
Epub 2017 May 10
doi: 10.1024/0301-1526/a000627.
<span class="bold">PMID: </span><a href="/pubmed/28486869" target="_blank">28486869</a></div>
<div class="nl"><a target="_blank" href="/pubmed/22581395">Antihypertensive treatment and sexual dysfunction.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Manolis A,
Doumas M</span><br />
<span class="medgenPMjournal">Curr Hypertens Rep</span>
2012 Aug;14(4):285-92.
doi: 10.1007/s11906-012-0276-5.
<span class="bold">PMID: </span><a href="/pubmed/22581395" target="_blank">22581395</a></div>
<div class="nl"><a target="_blank" href="/pubmed/12755990">Pathophysiology of erectile dysfunction.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Salonia A,
Briganti A,
Dehò F,
Naspro R,
Scapaticci E,
Scattoni V,
Rigatti P,
Montorsi F</span><br />
<span class="medgenPMjournal">Int J Androl</span>
2003 Jun;26(3):129-36.
doi: 10.1046/j.1365-2605.2003.00342.x.
<span class="bold">PMID: </span><a href="/pubmed/12755990" target="_blank">12755990</a></div>
<div class="nl"><a target="_blank" href="/pubmed/10076652">Cigarette smoking and erectile dysfunction.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Jeremy JY,
Mikhailidis DP</span><br />
<span class="medgenPMjournal">J R Soc Promot Health</span>
1998 Jun;118(3):151-5.
doi: 10.1177/146642409811800305.
<span class="bold">PMID: </span><a href="/pubmed/10076652" target="_blank">10076652</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Impotence%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1887)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/28486869">Erectile dysfunction - overview from a cardiovascular perspective.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Baumann F,
Hehli D,
Makaloski V,
Schumacher M,
Schönhofen H,
Diehm N</span><br />
<span class="medgenPMjournal">Vasa</span>
2017 Aug;46(5):347-353.
Epub 2017 May 10
doi: 10.1024/0301-1526/a000627.
<span class="bold">PMID: </span><a href="/pubmed/28486869" target="_blank">28486869</a></div>
<div class="nl"><a target="_blank" href="/pubmed/24182973">Office-based management of impotence and Peyronie's disease.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tapscott AH,
Hakim LS</span><br />
<span class="medgenPMjournal">Urol Clin North Am</span>
2013 Nov;40(4):521-43.
Epub 2013 Sep 3
doi: 10.1016/j.ucl.2013.07.003.
<span class="bold">PMID: </span><a href="/pubmed/24182973" target="_blank">24182973</a></div>
<div class="nl"><a target="_blank" href="/pubmed/22971225">SOP: corpus cavernosum assessment (cavernosography/cavernosometry).</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Glina S,
Ghanem H</span><br />
<span class="medgenPMjournal">J Sex Med</span>
2013 Jan;10(1):111-4.
Epub 2012 Sep 12
doi: 10.1111/j.1743-6109.2012.02795.x.
<span class="bold">PMID: </span><a href="/pubmed/22971225" target="_blank">22971225</a></div>
<div class="nl"><a target="_blank" href="/pubmed/10568586">Male impotence.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Morgentaler A</span><br />
<span class="medgenPMjournal">Lancet</span>
1999 Nov 13;354(9191):1713-8.
doi: 10.1016/S0140-6736(99)06586-1.
<span class="bold">PMID: </span><a href="/pubmed/10568586" target="_blank">10568586</a></div>
<div class="nl"><a target="_blank" href="/pubmed/10458660">Penile arteriography.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Borge MA</span><br />
<span class="medgenPMjournal">Tech Urol</span>
1999 Jun;5(2):81-6.
<span class="bold">PMID: </span><a href="/pubmed/10458660" target="_blank">10458660</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Impotence%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1425)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/25532580">Endovascular treatment of vasculogenic erectile dysfunction.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kim ED,
Owen RC,
White GS,
Elkelany OO,
Rahnema CD</span><br />
<span class="medgenPMjournal">Asian J Androl</span>
2015 Jan-Feb;17(1):40-3.
doi: 10.4103/1008-682x.143752.
<span class="bold">PMID: </span><a href="/pubmed/25532580" target="_blank">25532580</a><a href="/pmc/articles/PMC4291874" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23040455">Erectile dysfunction.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Shamloul R,
Ghanem H</span><br />
<span class="medgenPMjournal">Lancet</span>
2013 Jan 12;381(9861):153-65.
Epub 2012 Oct 5
doi: 10.1016/S0140-6736(12)60520-0.
<span class="bold">PMID: </span><a href="/pubmed/23040455" target="_blank">23040455</a></div>
<div class="nl"><a target="_blank" href="/pubmed/16336086">Exisulind in the treatment of prostate cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Webster WS,
Leibovich BC</span><br />
<span class="medgenPMjournal">Expert Rev Anticancer Ther</span>
2005 Dec;5(6):957-62.
doi: 10.1586/14737140.5.6.957.
<span class="bold">PMID: </span><a href="/pubmed/16336086" target="_blank">16336086</a></div>
<div class="nl"><a target="_blank" href="/pubmed/12755990">Pathophysiology of erectile dysfunction.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Salonia A,
Briganti A,
Dehò F,
Naspro R,
Scapaticci E,
Scattoni V,
Rigatti P,
Montorsi F</span><br />
<span class="medgenPMjournal">Int J Androl</span>
2003 Jun;26(3):129-36.
doi: 10.1046/j.1365-2605.2003.00342.x.
<span class="bold">PMID: </span><a href="/pubmed/12755990" target="_blank">12755990</a></div>
<div class="nl"><a target="_blank" href="/pubmed/10076652">Cigarette smoking and erectile dysfunction.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Jeremy JY,
Mikhailidis DP</span><br />
<span class="medgenPMjournal">J R Soc Promot Health</span>
1998 Jun;118(3):151-5.
doi: 10.1177/146642409811800305.
<span class="bold">PMID: </span><a href="/pubmed/10076652" target="_blank">10076652</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Impotence%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1853)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/30014525">Erectile dysfunction and atrial fibrillation: A systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Chokesuwattanaskul R,
Thongprayoon C,
Pachariyanon P,
Sharma K,
Ungprasert P,
Bathini T,
Cheungpasitporn W</span><br />
<span class="medgenPMjournal">Int J Urol</span>
2018 Aug;25(8):752-757.
Epub 2018 Jul 16
doi: 10.1111/iju.13725.
<span class="bold">PMID: </span><a href="/pubmed/30014525" target="_blank">30014525</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28486869">Erectile dysfunction - overview from a cardiovascular perspective.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Baumann F,
Hehli D,
Makaloski V,
Schumacher M,
Schönhofen H,
Diehm N</span><br />
<span class="medgenPMjournal">Vasa</span>
2017 Aug;46(5):347-353.
Epub 2017 May 10
doi: 10.1024/0301-1526/a000627.
<span class="bold">PMID: </span><a href="/pubmed/28486869" target="_blank">28486869</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23040455">Erectile dysfunction.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Shamloul R,
Ghanem H</span><br />
<span class="medgenPMjournal">Lancet</span>
2013 Jan 12;381(9861):153-65.
Epub 2012 Oct 5
doi: 10.1016/S0140-6736(12)60520-0.
<span class="bold">PMID: </span><a href="/pubmed/23040455" target="_blank">23040455</a></div>
<div class="nl"><a target="_blank" href="/pubmed/22971225">SOP: corpus cavernosum assessment (cavernosography/cavernosometry).</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Glina S,
Ghanem H</span><br />
<span class="medgenPMjournal">J Sex Med</span>
2013 Jan;10(1):111-4.
Epub 2012 Sep 12
doi: 10.1111/j.1743-6109.2012.02795.x.
<span class="bold">PMID: </span><a href="/pubmed/22971225" target="_blank">22971225</a></div>
<div class="nl"><a target="_blank" href="/pubmed/6341341">Psychological factors involved in impotence. A review of the literature.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Turnbull JM,
Weinberg PC</span><br />
<span class="medgenPMjournal">J Androl</span>
1983 Jan-Feb;4(1):59-66.
doi: 10.1002/j.1939-4640.1983.tb00720.x.
<span class="bold">PMID: </span><a href="/pubmed/6341341" target="_blank">6341341</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Impotence%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (855)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/28486869">Erectile dysfunction - overview from a cardiovascular perspective.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Baumann F,
Hehli D,
Makaloski V,
Schumacher M,
Schönhofen H,
Diehm N</span><br />
<span class="medgenPMjournal">Vasa</span>
2017 Aug;46(5):347-353.
Epub 2017 May 10
doi: 10.1024/0301-1526/a000627.
<span class="bold">PMID: </span><a href="/pubmed/28486869" target="_blank">28486869</a></div>
<div class="nl"><a target="_blank" href="/pubmed/24423973">All men with vasculogenic erectile dysfunction require a cardiovascular workup.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Miner M,
Nehra A,
Jackson G,
Bhasin S,
Billups K,
Burnett AL,
Buvat J,
Carson C,
Cunningham G,
Ganz P,
Goldstein I,
Guay A,
Hackett G,
Kloner RA,
Kostis JB,
LaFlamme KE,
Montorsi P,
Ramsey M,
Rosen R,
Sadovsky R,
Seftel A,
Shabsigh R,
Vlachopoulos C,
Wu F</span><br />
<span class="medgenPMjournal">Am J Med</span>
2014 Mar;127(3):174-82.
Epub 2013 Nov 1
doi: 10.1016/j.amjmed.2013.10.013.
<span class="bold">PMID: </span><a href="/pubmed/24423973" target="_blank">24423973</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23040455">Erectile dysfunction.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Shamloul R,
Ghanem H</span><br />
<span class="medgenPMjournal">Lancet</span>
2013 Jan 12;381(9861):153-65.
Epub 2012 Oct 5
doi: 10.1016/S0140-6736(12)60520-0.
<span class="bold">PMID: </span><a href="/pubmed/23040455" target="_blank">23040455</a></div>
<div class="nl"><a target="_blank" href="/pubmed/22971225">SOP: corpus cavernosum assessment (cavernosography/cavernosometry).</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Glina S,
Ghanem H</span><br />
<span class="medgenPMjournal">J Sex Med</span>
2013 Jan;10(1):111-4.
Epub 2012 Sep 12
doi: 10.1111/j.1743-6109.2012.02795.x.
<span class="bold">PMID: </span><a href="/pubmed/22971225" target="_blank">22971225</a></div>
<div class="nl"><a target="_blank" href="/pubmed/10076652">Cigarette smoking and erectile dysfunction.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Jeremy JY,
Mikhailidis DP</span><br />
<span class="medgenPMjournal">J R Soc Promot Health</span>
1998 Jun;118(3):151-5.
doi: 10.1177/146642409811800305.
<span class="bold">PMID: </span><a href="/pubmed/10076652" target="_blank">10076652</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Impotence%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1011)</a></div></div>
</div>
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<div class="nl"><a target="_blank" href="/pubmed/34013796">The Association Between Periodontitis and Erectile Dysfunction: A Systematic Review and Meta-Analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Farook F,
Al Meshrafi A,
Mohamed Nizam N,
Al Shammari A</span><br />
<span class="medgenPMjournal">Am J Mens Health</span>
2021 May-Jun;15(3):15579883211007277.
doi: 10.1177/15579883211007277.
<span class="bold">PMID: </span><a href="/pubmed/34013796" target="_blank">34013796</a><a href="/pmc/articles/PMC8142012" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31793443">Epidemiology regarding penile prosthetic surgery.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Saavedra-Belaunde JA,
Clavell-Hernandez J,
Wang R</span><br />
<span class="medgenPMjournal">Asian J Androl</span>
2020 Jan-Feb;22(1):2-7.
doi: 10.4103/aja.aja_124_19.
<span class="bold">PMID: </span><a href="/pubmed/31793443" target="_blank">31793443</a><a href="/pmc/articles/PMC6958974" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/31795911">Angiotensin Receptor Blockers for Erectile Dysfunction in Hypertensive Men: A Brief Meta-Analysis of Randomized Control Trials.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ismail SB,
Noor NM,
Hussain NHN,
Sulaiman Z,
Shamsudin MA,
Irfan M</span><br />
<span class="medgenPMjournal">Am J Mens Health</span>
2019 Nov-Dec;13(6):1557988319892735.
doi: 10.1177/1557988319892735.
<span class="bold">PMID: </span><a href="/pubmed/31795911" target="_blank">31795911</a><a href="/pmc/articles/PMC6893938" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30740770">Platelet indices and erectile dysfunction: A systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Yang G,
Muzepper M</span><br />
<span class="medgenPMjournal">Andrologia</span>
2019 Jun;51(5):e13248.
Epub 2019 Feb 10
doi: 10.1111/and.13248.
<span class="bold">PMID: </span><a href="/pubmed/30740770" target="_blank">30740770</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28622464">The impact of drugs on male fertility: a review.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Semet M,
Paci M,
Saïas-Magnan J,
Metzler-Guillemain C,
Boissier R,
Lejeune H,
Perrin J</span><br />
<span class="medgenPMjournal">Andrology</span>
2017 Jul;5(4):640-663.
Epub 2017 Jun 16
doi: 10.1111/andr.12366.
<span class="bold">PMID: </span><a href="/pubmed/28622464" target="_blank">28622464</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Impotence%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (53)</a></div></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22impotence%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Impotence%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=5" href="/portal/utils/pageresolver.fcgi?recordid=67d57c1d2f30673f7ba03f3a">Homo sapiens BAC clone RP13-530H6 from 7, complete sequence</a>
<div class="ralinkpop offscreen_noflow">Homo sapiens BAC clone RP13-530H6 from 7, complete sequence<div class="brieflinkpopdesc">gi|18855125|gb|AC099394.6||gnl|wugs 3-530H6</div></div>
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