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<meta name="keywords" content="C5139292, decreased fef25-75%, decreased forced expiratory flow 25-75%, finding, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A reduction compared to the predicted value of the forced expiratory flow over the middle one-half of the FVC; the average flow from the point at which 25% of the FVC has been exhaled to the point at which 75% of the FVC has been exhaled." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
|
||
UID=1686759
|
||
ConceptID=C5139292
|
||
-->
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||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Decreased forced expiratory flow 25-75%</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1686759</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5139292</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Decreased FEF25-75%</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0032359">HP:0032359</a></td></tr>
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</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">A reduction compared to the predicted value of the forced expiratory flow over the middle one-half of the FVC; the average flow from the point at which 25% of the FVC has been exhaled to the point at which 75% of the FVC has been exhaled. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
|
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</div>
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||
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||
<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Decreased forced expiratory flow 25-75%</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/866322" ref="tree=MeSH" title="MedGen record for Abnormality of the respiratory system">Abnormality of the respiratory system</a></span><ul><li><span class="TLline"><a href="/medgen/220360" ref="tree=MeSH" title="MedGen record for Abnormal respiratory system physiology">Abnormal respiratory system physiology</a></span><ul><li><span class="TLline"><a href="/medgen/635153" ref="tree=MeSH" title="MedGen record for Abnormality on pulmonary function testing">Abnormality on pulmonary function testing</a></span><ul><li><span class="matched_ds">Decreased forced expiratory flow 25-75%</span><ul><li><span class="TLline"><a href="/medgen/1704624" ref="tree=MeSH" title="MedGen record for Decreased post-bronchodilator forced expiratory flow 25-75%">Decreased post-bronchodilator forced expiratory flow 25-75%</a></span></li><li><span class="TLline"><a href="/medgen/1688020" ref="tree=MeSH" title="MedGen record for Decreased pre-bronchodilator forced expiratory flow 25-75%">Decreased pre-bronchodilator forced expiratory flow 25-75%</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_41393"><div><strong>Cystic fibrosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>41393</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0010674</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Cystic fibrosis (CF) is a multisystem disease affecting epithelia of the respiratory tract, exocrine pancreas, intestine, hepatobiliary system, and exocrine sweat glands. Morbidities include recurrent sinusitis and bronchitis, progressive obstructive pulmonary disease with bronchiectasis, exocrine pancreatic deficiency and malnutrition, pancreatitis, gastrointestinal manifestations (meconium ileus, rectal prolapse, distal intestinal obstructive syndrome), liver disease, diabetes, male infertility due to hypoplasia or aplasia of the vas deferens, and reduced fertility or infertility in some women. Pulmonary disease is the major cause of morbidity and mortality in CF.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/41393">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1385152"><div><strong>Autosomal recessive limb-girdle muscular dystrophy type 2Y</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1385152</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4511482</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Autosomal recessive myopathy with rigid spine and distal joint contractures (MRRSDC) is characterized by onset of slowly progressive muscle weakness in the first or second decades of life. There is initial involvement of the proximal lower limbs, followed by distal upper and lower limb muscle weakness and atrophy. Other features include joint contractures, rigid spine, and restricted pulmonary function; some patients may have mild cardiac involvement (summary by Kayman-Kurekci et al., 2014).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1385152">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1385152" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Autosomal recessive limb-girdle muscular dystrophy type 2Y</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_41393" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cystic fibrosis</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/24236632">Short-term effectiveness of smoking-cessation treatment on respiratory function and CEA level.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pezzuto A,
|
||
Spoto C,
|
||
Vincenzi B,
|
||
Tonini G</span><br />
|
||
<span class="medgenPMjournal">J Comp Eff Res</span>
|
||
2013 May;2(3):335-43.
|
||
doi: 10.2217/cer.13.25.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24236632" target="_blank">24236632</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21679494">Systemic inflammation and its response to treatment in patients with asthma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Girdhar A,
|
||
Kumar V,
|
||
Singh A,
|
||
Menon B,
|
||
Vijayan VK</span><br />
|
||
<span class="medgenPMjournal">Respir Care</span>
|
||
2011 Jun;56(6):800-5.
|
||
doi: 10.4187/respcare.00601.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21679494" target="_blank">21679494</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18386434">FEF75 in asthma management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Luigi DB,
|
||
Emanuel DT,
|
||
Federica DB,
|
||
Fabrizio DT</span><br />
|
||
<span class="medgenPMjournal">Eur Ann Allergy Clin Immunol</span>
|
||
2007 Dec;39(10):333-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18386434" target="_blank">18386434</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(decreased%20forced%20expiratory%20flow%2025-75%25)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (3)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36202407">Small airway function measured using forced expiratory flow between 25% and 75% of vital capacity and its relationship to airflow limitation in symptomatic ever-smokers: a cross-sectional study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Alobaidi NY,
|
||
Almeshari M,
|
||
Stockley J,
|
||
Stockley RA,
|
||
Sapey E</span><br />
|
||
<span class="medgenPMjournal">BMJ Open Respir Res</span>
|
||
2022 Oct;9(1)
|
||
doi: 10.1136/bmjresp-2022-001385.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36202407" target="_blank">36202407</a><a href="/pmc/articles/PMC9540854" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35247313">The role of small airway dysfunction in asthma control and exacerbations: a longitudinal, observational analysis using data from the ATLANTIS study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kraft M,
|
||
Richardson M,
|
||
Hallmark B,
|
||
Billheimer D,
|
||
Van den Berge M,
|
||
Fabbri LM,
|
||
Van der Molen T,
|
||
Nicolini G,
|
||
Papi A,
|
||
Rabe KF,
|
||
Singh D,
|
||
Brightling C,
|
||
Siddiqui S;
|
||
ATLANTIS study group</span><br />
|
||
<span class="medgenPMjournal">Lancet Respir Med</span>
|
||
2022 Jul;10(7):661-668.
|
||
Epub 2022 Mar 2
|
||
doi: 10.1016/S2213-2600(21)00536-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35247313" target="_blank">35247313</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34058148">Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Radicioni G,
|
||
Ceppe A,
|
||
Ford AA,
|
||
Alexis NE,
|
||
Barr RG,
|
||
Bleecker ER,
|
||
Christenson SA,
|
||
Cooper CB,
|
||
Han MK,
|
||
Hansel NN,
|
||
Hastie AT,
|
||
Hoffman EA,
|
||
Kanner RE,
|
||
Martinez FJ,
|
||
Ozkan E,
|
||
Paine R 3rd,
|
||
Woodruff PG,
|
||
O'Neal WK,
|
||
Boucher RC,
|
||
Kesimer M</span><br />
|
||
<span class="medgenPMjournal">Lancet Respir Med</span>
|
||
2021 Nov;9(11):1241-1254.
|
||
Epub 2021 May 28
|
||
doi: 10.1016/S2213-2600(21)00079-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34058148" target="_blank">34058148</a><a href="/pmc/articles/PMC8570975" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33962511">Effect of osteopathic manipulative treatment on pulmonary function testing in children with asthma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jones LM,
|
||
Regan C,
|
||
Wolf K,
|
||
Bryant J,
|
||
Rakowsky A,
|
||
Pe M,
|
||
Snyder DA</span><br />
|
||
<span class="medgenPMjournal">J Osteopath Med</span>
|
||
2021 May 7;121(6):589-596.
|
||
doi: 10.1515/jom-2020-0040.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33962511" target="_blank">33962511</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33468239">Association between air flow limitation and body composition in young adults.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Muñoz-Cofré R,
|
||
Lizana PA,
|
||
Cabello ME,
|
||
García-Herrera C,
|
||
Del Sol M</span><br />
|
||
<span class="medgenPMjournal">J Physiol Anthropol</span>
|
||
2021 Jan 19;40(1):2.
|
||
doi: 10.1186/s40101-021-00252-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33468239" target="_blank">33468239</a><a href="/pmc/articles/PMC7816486" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Decreased%20forced%20expiratory%20flow%2025-75%25%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (141)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36202407">Small airway function measured using forced expiratory flow between 25% and 75% of vital capacity and its relationship to airflow limitation in symptomatic ever-smokers: a cross-sectional study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Alobaidi NY,
|
||
Almeshari M,
|
||
Stockley J,
|
||
Stockley RA,
|
||
Sapey E</span><br />
|
||
<span class="medgenPMjournal">BMJ Open Respir Res</span>
|
||
2022 Oct;9(1)
|
||
doi: 10.1136/bmjresp-2022-001385.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36202407" target="_blank">36202407</a><a href="/pmc/articles/PMC9540854" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35247313">The role of small airway dysfunction in asthma control and exacerbations: a longitudinal, observational analysis using data from the ATLANTIS study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kraft M,
|
||
Richardson M,
|
||
Hallmark B,
|
||
Billheimer D,
|
||
Van den Berge M,
|
||
Fabbri LM,
|
||
Van der Molen T,
|
||
Nicolini G,
|
||
Papi A,
|
||
Rabe KF,
|
||
Singh D,
|
||
Brightling C,
|
||
Siddiqui S;
|
||
ATLANTIS study group</span><br />
|
||
<span class="medgenPMjournal">Lancet Respir Med</span>
|
||
2022 Jul;10(7):661-668.
|
||
Epub 2022 Mar 2
|
||
doi: 10.1016/S2213-2600(21)00536-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35247313" target="_blank">35247313</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34058148">Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Radicioni G,
|
||
Ceppe A,
|
||
Ford AA,
|
||
Alexis NE,
|
||
Barr RG,
|
||
Bleecker ER,
|
||
Christenson SA,
|
||
Cooper CB,
|
||
Han MK,
|
||
Hansel NN,
|
||
Hastie AT,
|
||
Hoffman EA,
|
||
Kanner RE,
|
||
Martinez FJ,
|
||
Ozkan E,
|
||
Paine R 3rd,
|
||
Woodruff PG,
|
||
O'Neal WK,
|
||
Boucher RC,
|
||
Kesimer M</span><br />
|
||
<span class="medgenPMjournal">Lancet Respir Med</span>
|
||
2021 Nov;9(11):1241-1254.
|
||
Epub 2021 May 28
|
||
doi: 10.1016/S2213-2600(21)00079-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34058148" target="_blank">34058148</a><a href="/pmc/articles/PMC8570975" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33962511">Effect of osteopathic manipulative treatment on pulmonary function testing in children with asthma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jones LM,
|
||
Regan C,
|
||
Wolf K,
|
||
Bryant J,
|
||
Rakowsky A,
|
||
Pe M,
|
||
Snyder DA</span><br />
|
||
<span class="medgenPMjournal">J Osteopath Med</span>
|
||
2021 May 7;121(6):589-596.
|
||
doi: 10.1515/jom-2020-0040.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33962511" target="_blank">33962511</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26688518">Forced midexpiratory flow between 25% and 75% of forced vital capacity is associated with long-term persistence of asthma and poor asthma outcomes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Siroux V,
|
||
Boudier A,
|
||
Dolgopoloff M,
|
||
Chanoine S,
|
||
Bousquet J,
|
||
Gormand F,
|
||
Just J,
|
||
Le Moual N,
|
||
Nadif R,
|
||
Pison C,
|
||
Varraso R,
|
||
Matran R,
|
||
Pin I</span><br />
|
||
<span class="medgenPMjournal">J Allergy Clin Immunol</span>
|
||
2016 Jun;137(6):1709-1716.e6.
|
||
Epub 2015 Dec 11
|
||
doi: 10.1016/j.jaci.2015.10.029.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26688518" target="_blank">26688518</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Decreased%20forced%20expiratory%20flow%2025-75%25%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (56)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38413986">Improvements in lung function following vitamin C supplementation to pregnant smokers are associated with buccal DNA methylation at 5 years of age.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shorey-Kendrick LE,
|
||
McEvoy CT,
|
||
Milner K,
|
||
Harris J,
|
||
Brownsberger J,
|
||
Tepper RS,
|
||
Park B,
|
||
Gao L,
|
||
Vu A,
|
||
Morris CD,
|
||
Spindel ER</span><br />
|
||
<span class="medgenPMjournal">Clin Epigenetics</span>
|
||
2024 Feb 27;16(1):35.
|
||
doi: 10.1186/s13148-024-01644-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38413986" target="_blank">38413986</a><a href="/pmc/articles/PMC10900729" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38061586">Exposure to endocrine-disrupting plasticisers and lung function in children and adolescents: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Boissiere-O'Neill T,
|
||
Lee WR,
|
||
Blake TL,
|
||
Sly PD,
|
||
Vilcins D</span><br />
|
||
<span class="medgenPMjournal">Environ Res</span>
|
||
2024 Feb 15;243:117751.
|
||
Epub 2023 Dec 5
|
||
doi: 10.1016/j.envres.2023.117751.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38061586" target="_blank">38061586</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36736759">The impact of occupational exposure to crystalline silica dust on respiratory function (airway obstruction and FEF(25-75)) in the French general population.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wardyn PM,
|
||
Edme JL,
|
||
de Broucker V,
|
||
Cherot-Kornobis N,
|
||
Ringeval D,
|
||
Amouyel P,
|
||
Sobaszek A,
|
||
Dauchet L,
|
||
Hulo S</span><br />
|
||
<span class="medgenPMjournal">Environ Res</span>
|
||
2023 Apr 1;222:115382.
|
||
Epub 2023 Feb 1
|
||
doi: 10.1016/j.envres.2023.115382.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36736759" target="_blank">36736759</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33962511">Effect of osteopathic manipulative treatment on pulmonary function testing in children with asthma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jones LM,
|
||
Regan C,
|
||
Wolf K,
|
||
Bryant J,
|
||
Rakowsky A,
|
||
Pe M,
|
||
Snyder DA</span><br />
|
||
<span class="medgenPMjournal">J Osteopath Med</span>
|
||
2021 May 7;121(6):589-596.
|
||
doi: 10.1515/jom-2020-0040.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33962511" target="_blank">33962511</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10673171">Forced expiratory flows and volumes in infants. Normative data and lung growth.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Jones M,
|
||
Castile R,
|
||
Davis S,
|
||
Kisling J,
|
||
Filbrun D,
|
||
Flucke R,
|
||
Goldstein A,
|
||
Emsley C,
|
||
Ambrosius W,
|
||
Tepper RS</span><br />
|
||
<span class="medgenPMjournal">Am J Respir Crit Care Med</span>
|
||
2000 Feb;161(2 Pt 1):353-9.
|
||
doi: 10.1164/ajrccm.161.2.9903026.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10673171" target="_blank">10673171</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Decreased%20forced%20expiratory%20flow%2025-75%25%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (107)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35247313">The role of small airway dysfunction in asthma control and exacerbations: a longitudinal, observational analysis using data from the ATLANTIS study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kraft M,
|
||
Richardson M,
|
||
Hallmark B,
|
||
Billheimer D,
|
||
Van den Berge M,
|
||
Fabbri LM,
|
||
Van der Molen T,
|
||
Nicolini G,
|
||
Papi A,
|
||
Rabe KF,
|
||
Singh D,
|
||
Brightling C,
|
||
Siddiqui S;
|
||
ATLANTIS study group</span><br />
|
||
<span class="medgenPMjournal">Lancet Respir Med</span>
|
||
2022 Jul;10(7):661-668.
|
||
Epub 2022 Mar 2
|
||
doi: 10.1016/S2213-2600(21)00536-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35247313" target="_blank">35247313</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34058148">Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Radicioni G,
|
||
Ceppe A,
|
||
Ford AA,
|
||
Alexis NE,
|
||
Barr RG,
|
||
Bleecker ER,
|
||
Christenson SA,
|
||
Cooper CB,
|
||
Han MK,
|
||
Hansel NN,
|
||
Hastie AT,
|
||
Hoffman EA,
|
||
Kanner RE,
|
||
Martinez FJ,
|
||
Ozkan E,
|
||
Paine R 3rd,
|
||
Woodruff PG,
|
||
O'Neal WK,
|
||
Boucher RC,
|
||
Kesimer M</span><br />
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2021 Nov;9(11):1241-1254.
|
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Epub 2021 May 28
|
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doi: 10.1016/S2213-2600(21)00079-5.
|
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<span class="bold">PMID: </span><a href="/pubmed/34058148" target="_blank">34058148</a><a href="/pmc/articles/PMC8570975" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29659309">Peak expiratory flow in obese subjects in different positions.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Nascimento JP,
|
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Perossi L,
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Holtz M,
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Baddini-Martinez JA,
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2019 Oct;35(10):956-963.
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Epub 2018 Apr 16
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<span class="bold">PMID: </span><a href="/pubmed/29659309" target="_blank">29659309</a></div>
|
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|
||
<div class="nl"><a target="_blank" href="/pubmed/26688518">Forced midexpiratory flow between 25% and 75% of forced vital capacity is associated with long-term persistence of asthma and poor asthma outcomes.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Siroux V,
|
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Boudier A,
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Dolgopoloff M,
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Chanoine S,
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Just J,
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<span class="bold">PMID: </span><a href="/pubmed/26688518" target="_blank">26688518</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17390762">Role of forced expiratory flow at 25-75% as an early marker of small airways impairment in subjects with allergic rhinitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Marseglia GL,
|
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Cirillo I,
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Vizzaccaro A,
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Klersy C,
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Tosca MA,
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La Rosa M,
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Marseglia A,
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<span class="bold">PMID: </span><a href="/pubmed/17390762" target="_blank">17390762</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Decreased%20forced%20expiratory%20flow%2025-75%25%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (72)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36736759">The impact of occupational exposure to crystalline silica dust on respiratory function (airway obstruction and FEF(25-75)) in the French general population.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wardyn PM,
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Edme JL,
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de Broucker V,
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Cherot-Kornobis N,
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Ringeval D,
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Amouyel P,
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Sobaszek A,
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<span class="medgenPMjournal">Environ Res</span>
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2023 Apr 1;222:115382.
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Epub 2023 Feb 1
|
||
doi: 10.1016/j.envres.2023.115382.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36736759" target="_blank">36736759</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36202407">Small airway function measured using forced expiratory flow between 25% and 75% of vital capacity and its relationship to airflow limitation in symptomatic ever-smokers: a cross-sectional study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Alobaidi NY,
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Almeshari M,
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Stockley J,
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||
Stockley RA,
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||
Sapey E</span><br />
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||
<span class="medgenPMjournal">BMJ Open Respir Res</span>
|
||
2022 Oct;9(1)
|
||
doi: 10.1136/bmjresp-2022-001385.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36202407" target="_blank">36202407</a><a href="/pmc/articles/PMC9540854" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35247313">The role of small airway dysfunction in asthma control and exacerbations: a longitudinal, observational analysis using data from the ATLANTIS study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kraft M,
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||
Richardson M,
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Hallmark B,
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Billheimer D,
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Van den Berge M,
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Fabbri LM,
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Van der Molen T,
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Nicolini G,
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Papi A,
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Rabe KF,
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Singh D,
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Brightling C,
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Siddiqui S;
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ATLANTIS study group</span><br />
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<span class="medgenPMjournal">Lancet Respir Med</span>
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||
2022 Jul;10(7):661-668.
|
||
Epub 2022 Mar 2
|
||
doi: 10.1016/S2213-2600(21)00536-1.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35247313" target="_blank">35247313</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34058148">Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Radicioni G,
|
||
Ceppe A,
|
||
Ford AA,
|
||
Alexis NE,
|
||
Barr RG,
|
||
Bleecker ER,
|
||
Christenson SA,
|
||
Cooper CB,
|
||
Han MK,
|
||
Hansel NN,
|
||
Hastie AT,
|
||
Hoffman EA,
|
||
Kanner RE,
|
||
Martinez FJ,
|
||
Ozkan E,
|
||
Paine R 3rd,
|
||
Woodruff PG,
|
||
O'Neal WK,
|
||
Boucher RC,
|
||
Kesimer M</span><br />
|
||
<span class="medgenPMjournal">Lancet Respir Med</span>
|
||
2021 Nov;9(11):1241-1254.
|
||
Epub 2021 May 28
|
||
doi: 10.1016/S2213-2600(21)00079-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34058148" target="_blank">34058148</a><a href="/pmc/articles/PMC8570975" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33468239">Association between air flow limitation and body composition in young adults.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Muñoz-Cofré R,
|
||
Lizana PA,
|
||
Cabello ME,
|
||
García-Herrera C,
|
||
Del Sol M</span><br />
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||
<span class="medgenPMjournal">J Physiol Anthropol</span>
|
||
2021 Jan 19;40(1):2.
|
||
doi: 10.1186/s40101-021-00252-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33468239" target="_blank">33468239</a><a href="/pmc/articles/PMC7816486" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Decreased%20forced%20expiratory%20flow%2025-75%25%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (114)</a></div></div>
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<div class="nl"><a target="_blank" href="/pubmed/38061586">Exposure to endocrine-disrupting plasticisers and lung function in children and adolescents: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Boissiere-O'Neill T,
|
||
Lee WR,
|
||
Blake TL,
|
||
Sly PD,
|
||
Vilcins D</span><br />
|
||
<span class="medgenPMjournal">Environ Res</span>
|
||
2024 Feb 15;243:117751.
|
||
Epub 2023 Dec 5
|
||
doi: 10.1016/j.envres.2023.117751.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38061586" target="_blank">38061586</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Decreased%20forced%20expiratory%20flow%2025-75%25%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1)</a></div></div>
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