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<!--
|
||
UID=1670959
|
||
ConceptID=C4732780
|
||
-->
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||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Reduced blood urea nitrogen</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1670959</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4732780</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Reduced BUN</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0031969">HP:0031969</a></td></tr>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">An abnormally low concentration of urea nitrogen in the blood. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
|
||
</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Reduced blood urea nitrogen</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/867398" ref="tree=MeSH" title="MedGen record for Abnormality of metabolism/homeostasis">Abnormality of metabolism/homeostasis</a></span><ul><li><span class="TLline"><a href="/medgen/1701080" ref="tree=MeSH" title="MedGen record for Abnormal circulating metabolite concentration">Abnormal circulating metabolite concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1864085" ref="tree=MeSH" title="MedGen record for Abnormal circulating organic compound concentration">Abnormal circulating organic compound concentration</a></span><ul><li><span class="TLline"><a href="/medgen/870875" ref="tree=MeSH" title="MedGen record for Abnormal circulating nitrogen compound concentration">Abnormal circulating nitrogen compound concentration</a></span><ul><li><span class="TLline"><a href="/medgen/614150" ref="tree=MeSH" title="MedGen record for Abnormal blood urea nitrogen concentration">Abnormal blood urea nitrogen concentration</a></span><ul><li><span class="matched_ds">Reduced blood urea nitrogen</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_336877"><div><strong>Nephrogenic syndrome of inappropriate antidiuresis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>336877</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1845202</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a common cause of hyponatremia. The syndrome manifests as an inability to excrete a free water load, with inappropriately concentrated urine and resultant hyponatremia, hypoosmolality, and natriuresis. SIADH occurs in a setting of normal blood volume, without evidence of renal disease or deficiency of thyroxine or cortisol. Although usually transient, SIADH may be chronic; it is often associated with drug use or a lesion in the central nervous system or lung. When the cardinal features of SIADH were defined by Bartter and Schwartz (1967), levels of AVP could not be measured. Subsequently, radioimmunoassays revealed that SIADH is usually associated with measurably elevated serum levels of AVP. Nephrogenic syndrome of inappropriate antidiuresis (NSIAD) is characterized by a clinical picture similar to SIADH, but is associated with undetectable levels of AVP (Feldman et al., 2005).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/336877">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_419735"><div><strong>Nephropathic cystinosis</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>419735</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C2931187</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Cystinosis comprises three allelic phenotypes: Nephropathic cystinosis in untreated children is characterized by renal Fanconi syndrome, poor growth, hypophosphatemic/calcipenic rickets, impaired glomerular function resulting in complete glomerular failure, and accumulation of cystine in almost all cells, leading to cellular dysfunction with tissue and organ impairment. The typical untreated child has short stature, rickets, and photophobia. Failure to thrive is generally noticed after approximately age six months; signs of renal tubular Fanconi syndrome (polyuria, polydipsia, dehydration, and acidosis) appear as early as age six months; corneal crystals can be present before age one year and are always present after age 16 months. Prior to the use of renal transplantation and cystine-depleting therapy, the life span in nephropathic cystinosis was no longer than ten years. With these interventions, affected individuals can survive at least into the mid-forties or fifties with satisfactory quality of life. Intermediate cystinosis is characterized by all the typical manifestations of nephropathic cystinosis, but onset is at a later age. Renal glomerular failure occurs in all untreated affected individuals, usually between ages 15 and 25 years. The non-nephropathic (ocular) form of cystinosis is characterized clinically only by photophobia resulting from corneal cystine crystal accumulation.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/419735">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_336877" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Nephrogenic syndrome of inappropriate antidiuresis</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_419735" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Nephropathic cystinosis</a></div></div>
|
||
</div>
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||
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||
<div class="portlet mgSection" id="ID_105">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39284427">Mechanism of Biqi capsules in the treatment of gout based on network pharmacology and experimental verification.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Li G,
|
||
Du S,
|
||
Yan S,
|
||
Wang Y,
|
||
Bu R,
|
||
Cheng M,
|
||
Zhang Y,
|
||
Chen Q,
|
||
Wu Y,
|
||
Zhang X,
|
||
Wang D,
|
||
Wang T</span><br />
|
||
<span class="medgenPMjournal">J Ethnopharmacol</span>
|
||
2025 Jan 30;337(Pt 1):118817.
|
||
Epub 2024 Sep 14
|
||
doi: 10.1016/j.jep.2024.118817.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39284427" target="_blank">39284427</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/39456955">Early Diagnosis and Treatment of Kidney Injury: A Focus on Urine Protein.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zeng D,
|
||
Wang B,
|
||
Xiao Z,
|
||
Wang X,
|
||
Tang X,
|
||
Yao X,
|
||
Wang P,
|
||
Li M,
|
||
Dai Y,
|
||
Yu X</span><br />
|
||
<span class="medgenPMjournal">Int J Mol Sci</span>
|
||
2024 Oct 17;25(20)
|
||
doi: 10.3390/ijms252011171.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39456955" target="_blank">39456955</a><a href="/pmc/articles/PMC11508809" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33592850">Efficacy and safety of blood purification in the treatment of deep burns: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang G,
|
||
Liu W,
|
||
Li J,
|
||
Wang D,
|
||
Duan J,
|
||
Luo H</span><br />
|
||
<span class="medgenPMjournal">Medicine (Baltimore)</span>
|
||
2021 Feb 5;100(5):e23968.
|
||
doi: 10.1097/MD.0000000000023968.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33592850" target="_blank">33592850</a><a href="/pmc/articles/PMC7870217" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(reduced%20blood%20urea%20nitrogen)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (67)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39015062">Effects of ginsenoside Rh2 on cisplatin-induced nephrotoxicity in renal tubular epithelial cells by inhibiting endoplasmic reticulum stress.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang L,
|
||
Hao X,
|
||
Li X,
|
||
Li Q,
|
||
Fang X</span><br />
|
||
<span class="medgenPMjournal">J Biochem Mol Toxicol</span>
|
||
2024 Aug;38(8):e23768.
|
||
doi: 10.1002/jbt.23768.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39015062" target="_blank">39015062</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32340375">Effect of Increased Daily Water Intake and Hydration on Health in Japanese Adults.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nakamura Y,
|
||
Watanabe H,
|
||
Tanaka A,
|
||
Yasui M,
|
||
Nishihira J,
|
||
Murayama N</span><br />
|
||
<span class="medgenPMjournal">Nutrients</span>
|
||
2020 Apr 23;12(4)
|
||
doi: 10.3390/nu12041191.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32340375" target="_blank">32340375</a><a href="/pmc/articles/PMC7231288" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31335763">Metformin Attenuates Cyclosporine A-induced Renal Fibrosis in Rats.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lin CX,
|
||
Li Y,
|
||
Liang S,
|
||
Tao J,
|
||
Zhang LS,
|
||
Su YF,
|
||
Huang YX,
|
||
Zhao ZK,
|
||
Liu SY,
|
||
Zheng JM</span><br />
|
||
<span class="medgenPMjournal">Transplantation</span>
|
||
2019 Oct;103(10):e285-e296.
|
||
doi: 10.1097/TP.0000000000002864.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31335763" target="_blank">31335763</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18722318">Cardiac resynchronization therapy improves renal function in human heart failure with reduced glomerular filtration rate.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Boerrigter G,
|
||
Costello-Boerrigter LC,
|
||
Abraham WT,
|
||
Sutton MG,
|
||
Heublein DM,
|
||
Kruger KM,
|
||
Hill MR,
|
||
McCullough PA,
|
||
Burnett JC Jr</span><br />
|
||
<span class="medgenPMjournal">J Card Fail</span>
|
||
2008 Sep;14(7):539-46.
|
||
Epub 2008 May 27
|
||
doi: 10.1016/j.cardfail.2008.03.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18722318" target="_blank">18722318</a><a href="/pmc/articles/PMC2717624" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/12009355">Effect of paracentesis of ascitic fluids on urinary output and blood indices in patients with severe ovarian hyperstimulation syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Levin I,
|
||
Almog B,
|
||
Avni A,
|
||
Baram A,
|
||
Lessing JB,
|
||
Gamzu R</span><br />
|
||
<span class="medgenPMjournal">Fertil Steril</span>
|
||
2002 May;77(5):986-8.
|
||
doi: 10.1016/s0015-0282(02)02973-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12009355" target="_blank">12009355</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Reduced%20blood%20urea%20nitrogen%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/28430139">The Metalloproteinase ADAM28 Promotes Metabolic Dysfunction in Mice.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Herat L,
|
||
Rudnicka C,
|
||
Okada Y,
|
||
Mochizuki S,
|
||
Schlaich M,
|
||
Matthews V</span><br />
|
||
<span class="medgenPMjournal">Int J Mol Sci</span>
|
||
2017 Apr 21;18(4)
|
||
doi: 10.3390/ijms18040884.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28430139" target="_blank">28430139</a><a href="/pmc/articles/PMC5412464" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Reduced%20blood%20urea%20nitrogen%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39015062">Effects of ginsenoside Rh2 on cisplatin-induced nephrotoxicity in renal tubular epithelial cells by inhibiting endoplasmic reticulum stress.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang L,
|
||
Hao X,
|
||
Li X,
|
||
Li Q,
|
||
Fang X</span><br />
|
||
<span class="medgenPMjournal">J Biochem Mol Toxicol</span>
|
||
2024 Aug;38(8):e23768.
|
||
doi: 10.1002/jbt.23768.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39015062" target="_blank">39015062</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32622666">Rutaecarpine derivative Cpd-6c alleviates acute kidney injury by targeting PDE4B, a key enzyme mediating inflammation in cisplatin nephropathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu XQ,
|
||
Jin J,
|
||
Li Z,
|
||
Jiang L,
|
||
Dong YH,
|
||
Cai YT,
|
||
Wu MF,
|
||
Wang JN,
|
||
Ma TT,
|
||
Wen JG,
|
||
Liu MM,
|
||
Li J,
|
||
Wu YG,
|
||
Meng XM</span><br />
|
||
<span class="medgenPMjournal">Biochem Pharmacol</span>
|
||
2020 Oct;180:114132.
|
||
Epub 2020 Jul 3
|
||
doi: 10.1016/j.bcp.2020.114132.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32622666" target="_blank">32622666</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32340375">Effect of Increased Daily Water Intake and Hydration on Health in Japanese Adults.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nakamura Y,
|
||
Watanabe H,
|
||
Tanaka A,
|
||
Yasui M,
|
||
Nishihira J,
|
||
Murayama N</span><br />
|
||
<span class="medgenPMjournal">Nutrients</span>
|
||
2020 Apr 23;12(4)
|
||
doi: 10.3390/nu12041191.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32340375" target="_blank">32340375</a><a href="/pmc/articles/PMC7231288" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31335763">Metformin Attenuates Cyclosporine A-induced Renal Fibrosis in Rats.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lin CX,
|
||
Li Y,
|
||
Liang S,
|
||
Tao J,
|
||
Zhang LS,
|
||
Su YF,
|
||
Huang YX,
|
||
Zhao ZK,
|
||
Liu SY,
|
||
Zheng JM</span><br />
|
||
<span class="medgenPMjournal">Transplantation</span>
|
||
2019 Oct;103(10):e285-e296.
|
||
doi: 10.1097/TP.0000000000002864.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31335763" target="_blank">31335763</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/9649574">Osteogenic protein-1 (bone morphogenetic protein-7) reduces severity of injury after ischemic acute renal failure in rat.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Vukicevic S,
|
||
Basic V,
|
||
Rogic D,
|
||
Basic N,
|
||
Shih MS,
|
||
Shepard A,
|
||
Jin D,
|
||
Dattatreyamurty B,
|
||
Jones W,
|
||
Dorai H,
|
||
Ryan S,
|
||
Griffiths D,
|
||
Maliakal J,
|
||
Jelic M,
|
||
Pastorcic M,
|
||
Stavljenic A,
|
||
Sampath TK</span><br />
|
||
<span class="medgenPMjournal">J Clin Invest</span>
|
||
1998 Jul 1;102(1):202-14.
|
||
doi: 10.1172/JCI2237.
|
||
<span class="bold">PMID: </span><a href="/pubmed/9649574" target="_blank">9649574</a><a href="/pmc/articles/PMC509082" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Reduced%20blood%20urea%20nitrogen%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (8)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/32622666">Rutaecarpine derivative Cpd-6c alleviates acute kidney injury by targeting PDE4B, a key enzyme mediating inflammation in cisplatin nephropathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu XQ,
|
||
Jin J,
|
||
Li Z,
|
||
Jiang L,
|
||
Dong YH,
|
||
Cai YT,
|
||
Wu MF,
|
||
Wang JN,
|
||
Ma TT,
|
||
Wen JG,
|
||
Liu MM,
|
||
Li J,
|
||
Wu YG,
|
||
Meng XM</span><br />
|
||
<span class="medgenPMjournal">Biochem Pharmacol</span>
|
||
2020 Oct;180:114132.
|
||
Epub 2020 Jul 3
|
||
doi: 10.1016/j.bcp.2020.114132.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32622666" target="_blank">32622666</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18722318">Cardiac resynchronization therapy improves renal function in human heart failure with reduced glomerular filtration rate.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Boerrigter G,
|
||
Costello-Boerrigter LC,
|
||
Abraham WT,
|
||
Sutton MG,
|
||
Heublein DM,
|
||
Kruger KM,
|
||
Hill MR,
|
||
McCullough PA,
|
||
Burnett JC Jr</span><br />
|
||
<span class="medgenPMjournal">J Card Fail</span>
|
||
2008 Sep;14(7):539-46.
|
||
Epub 2008 May 27
|
||
doi: 10.1016/j.cardfail.2008.03.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18722318" target="_blank">18722318</a><a href="/pmc/articles/PMC2717624" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Reduced%20blood%20urea%20nitrogen%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/32622666">Rutaecarpine derivative Cpd-6c alleviates acute kidney injury by targeting PDE4B, a key enzyme mediating inflammation in cisplatin nephropathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Liu XQ,
|
||
Jin J,
|
||
Li Z,
|
||
Jiang L,
|
||
Dong YH,
|
||
Cai YT,
|
||
Wu MF,
|
||
Wang JN,
|
||
Ma TT,
|
||
Wen JG,
|
||
Liu MM,
|
||
Li J,
|
||
Wu YG,
|
||
Meng XM</span><br />
|
||
<span class="medgenPMjournal">Biochem Pharmacol</span>
|
||
2020 Oct;180:114132.
|
||
Epub 2020 Jul 3
|
||
doi: 10.1016/j.bcp.2020.114132.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32622666" target="_blank">32622666</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22331429">Expression and function of transforming growth factor β in melioidosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Weehuizen TA,
|
||
Wieland CW,
|
||
van der Windt GJ,
|
||
Duitman JW,
|
||
Boon L,
|
||
Day NP,
|
||
Peacock SJ,
|
||
van der Poll T,
|
||
Wiersinga WJ</span><br />
|
||
<span class="medgenPMjournal">Infect Immun</span>
|
||
2012 May;80(5):1853-7.
|
||
Epub 2012 Feb 13
|
||
doi: 10.1128/IAI.05534-11.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22331429" target="_blank">22331429</a><a href="/pmc/articles/PMC3347439" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21493813">Conditional VHL gene deletion activates a local NO-VEGF axis in a balanced manner reinforcing resistance to endothelium-targeted glomerulonephropathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Morita T,
|
||
Kakinuma Y,
|
||
Kurabayashi A,
|
||
Fujieda M,
|
||
Sato T,
|
||
Shuin T,
|
||
Furihata M,
|
||
Wakiguchi H</span><br />
|
||
<span class="medgenPMjournal">Nephrol Dial Transplant</span>
|
||
2011 Dec;26(12):4023-31.
|
||
Epub 2011 Apr 14
|
||
doi: 10.1093/ndt/gfr176.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21493813" target="_blank">21493813</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18722318">Cardiac resynchronization therapy improves renal function in human heart failure with reduced glomerular filtration rate.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Boerrigter G,
|
||
Costello-Boerrigter LC,
|
||
Abraham WT,
|
||
Sutton MG,
|
||
Heublein DM,
|
||
Kruger KM,
|
||
Hill MR,
|
||
McCullough PA,
|
||
Burnett JC Jr</span><br />
|
||
<span class="medgenPMjournal">J Card Fail</span>
|
||
2008 Sep;14(7):539-46.
|
||
Epub 2008 May 27
|
||
doi: 10.1016/j.cardfail.2008.03.009.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18722318" target="_blank">18722318</a><a href="/pmc/articles/PMC2717624" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Reduced%20blood%20urea%20nitrogen%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4)</a></div></div>
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