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<meta name="keywords" content="C4727106, breast carcinoma metastatic in lymph node, breast carcinoma metastatic in the lymph nodes, neoplastic process, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="A carcinoma that arises from the breast and has spread to the lymph nodes." /><meta name="robots" content="index,nofollow,noarchive" />
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<title>Breast Carcinoma Metastatic in the Lymph Nodes (Concept Id: C4727106)
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<!--
UID=1659340
ConceptID=C4727106
-->
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Breast Carcinoma Metastatic in the Lymph Nodes</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1659340</dd><dt><span class="dotprefix"></span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS)&#10;Click for more information.">C4727106</a></dd><dt><span class="dotprefix"></span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
<td>Breast Carcinoma Metastatic in Lymph Node</td></tr>
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
<div class="portlet mgSection" id="ID_100">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">A carcinoma that arises from the breast and has spread to the lymph nodes. [from <a title="NCI Thesaurus" href="http://ncit.nci.nih.gov" class="defSource" target="_blank">NCI</a>]</div>
</div>
<div class="portlet mgSection" id="ID_118">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test,  </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test,  </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM,  </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>,  </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar  </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Breast Carcinoma Metastatic in the Lymph Nodes</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/871338" ref="tree=MeSH" title="MedGen record for Abnormality of the breast">Abnormality of the breast</a></span><ul><li><span class="TLline"><a href="/medgen/1627648" ref="tree=MeSH" title="MedGen record for Abnormal breast morphology">Abnormal breast morphology</a></span><ul><li><span class="TLline"><a href="/medgen/264172" ref="tree=MeSH" title="MedGen record for Breast neoplasm">Breast neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/146260" ref="tree=MeSH" title="MedGen record for Breast carcinoma">Breast carcinoma</a></span><ul><li><span class="TLline"><a href="/medgen/1651514" ref="tree=MeSH" title="MedGen record for Metastatic Breast Carcinoma">Metastatic Breast Carcinoma</a></span><ul><li><span class="matched_ds">Breast Carcinoma Metastatic in the Lymph Nodes</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
</div>
<div class="portlet mgSection" id="ID_105">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
<div class="nl"><a target="_blank" href="/pubmed/36112842">AIRO Breast Cancer Group Best Clinical Practice 2022 Update.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ciabattoni A,
Gregucci F,
De Rose F,
Falivene S,
Fozza A,
Daidone A,
Morra A,
Smaniotto D,
Barbara R,
Lozza L,
Vidali C,
Borghesi S,
Palumbo I,
Huscher A,
Perrucci E,
Baldissera A,
Tolento G,
Rovea P,
Franco P,
De Santis MC,
Grazia AD,
Marino L,
Meduri B,
Cucciarelli F,
Aristei C,
Bertoni F,
Guenzi M,
Leonardi MC,
Livi L,
Nardone L,
De Felice F,
Rosetto ME,
Mazzuoli L,
Anselmo P,
Arcidiacono F,
Barbarino R,
Martinetti M,
Pasinetti N,
Desideri I,
Marazzi F,
Ivaldi G,
Bonzano E,
Cavallari M,
Cerreta V,
Fusco V,
Sarno L,
Bonanni A,
Mangiacotti MG,
Prisco A,
Buonfrate G,
Andrulli D,
Fontana A,
Bagnoli R,
Marinelli L,
Reverberi C,
Scalabrino G,
Corazzi F,
Doino D,
Di Genesio-Pagliuca M,
Lazzari M,
Mascioni F,
Pace MP,
Mazza M,
Vitucci P,
Spera A,
Macchia G,
Boccardi M,
Evangelista G,
Sola B,
La Porta MR,
Fiorentino A,
Levra NG,
Ippolito E,
Silipigni S,
Osti MF,
Mignogna M,
Alessandro M,
Ursini LA,
Nuzzo M,
Meattini I,
D'Ermo G</span><br />
<span class="medgenPMjournal">Tumori</span>
2022 Jul;108(2_suppl):1-144.
doi: 10.1177/03008916221088885.
<span class="bold">PMID: </span><a href="/pubmed/36112842" target="_blank">36112842</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33023426">Indications and Strategy for Active Surveillance of Adult Low-Risk Papillary Thyroid Microcarcinoma: Consensus Statements from the Japan Association of Endocrine Surgery Task Force on Management for Papillary Thyroid Microcarcinoma.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sugitani I,
Ito Y,
Takeuchi D,
Nakayama H,
Masaki C,
Shindo H,
Teshima M,
Horiguchi K,
Yoshida Y,
Kanai T,
Hirokawa M,
Hames KY,
Tabei I,
Miyauchi A</span><br />
<span class="medgenPMjournal">Thyroid</span>
2021 Feb;31(2):183-192.
Epub 2020 Nov 2
doi: 10.1089/thy.2020.0330.
<span class="bold">PMID: </span><a href="/pubmed/33023426" target="_blank">33023426</a><a href="/pmc/articles/PMC7891203" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/20521754">Treatment of breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Maughan KL,
Lutterbie MA,
Ham PS</span><br />
<span class="medgenPMjournal">Am Fam Physician</span>
2010 Jun 1;81(11):1339-46.
<span class="bold">PMID: </span><a href="/pubmed/20521754" target="_blank">20521754</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(breast%20carcinoma%20metastatic%20in%20the%20lymph%20nodes)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (233)</a></div></div>
</div>
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
<div class="portlet mgSection" id="ID_103">
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
<div class="nl"><a target="_blank" href="/pubmed/36410350">Radiation Treatment for Breast Cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Bauer A</span><br />
<span class="medgenPMjournal">Surg Clin North Am</span>
2023 Feb;103(1):187-199.
Epub 2022 Oct 17
doi: 10.1016/j.suc.2022.08.015.
<span class="bold">PMID: </span><a href="/pubmed/36410350" target="_blank">36410350</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33464028">Ultrasound Evaluation of the Axilla in the Breast Imaging Setting.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Teichgraeber DC,
Perez F,
Guirguis MS,
Kapoor MM,
Whitman GJ</span><br />
<span class="medgenPMjournal">Ultrasound Q</span>
2021 Jan 13;37(1):43-51.
doi: 10.1097/RUQ.0000000000000546.
<span class="bold">PMID: </span><a href="/pubmed/33464028" target="_blank">33464028</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30845281">Intraoperative assessment of sentinel lymph nodes in early-stage breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Costin AI,
Păun I,
Vârcuş F,
Răcăreanu MM,
Lomaca I,
Costin AG,
Iovan L,
Radu L,
Mihai GM</span><br />
<span class="medgenPMjournal">Rom J Morphol Embryol</span>
2018;59(4):1033-1039.
<span class="bold">PMID: </span><a href="/pubmed/30845281" target="_blank">30845281</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30843891">Contemporary management of the axilla in breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Nurudeen S,
Hunt KK</span><br />
<span class="medgenPMjournal">Clin Adv Hematol Oncol</span>
2018 Dec;16(12):823-831.
<span class="bold">PMID: </span><a href="/pubmed/30843891" target="_blank">30843891</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23683750">Sentinel-lymph-node biopsy in patients with breast cancer before and after neoadjuvant chemotherapy (SENTINA): a prospective, multicentre cohort study.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kuehn T,
Bauerfeind I,
Fehm T,
Fleige B,
Hausschild M,
Helms G,
Lebeau A,
Liedtke C,
von Minckwitz G,
Nekljudova V,
Schmatloch S,
Schrenk P,
Staebler A,
Untch M</span><br />
<span class="medgenPMjournal">Lancet Oncol</span>
2013 Jun;14(7):609-18.
Epub 2013 May 15
doi: 10.1016/S1470-2045(13)70166-9.
<span class="bold">PMID: </span><a href="/pubmed/23683750" target="_blank">23683750</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Breast%20Carcinoma%20Metastatic%20in%20the%20Lymph%20Nodes%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2563)</a></div><h3 class="subhead">Diagnosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/35953742">ASO Author Reflections: Do We Need to Clip Metastatic Lymph Nodes at Diagnosis and Localize Them After Neoadjuvant Chemotherapy?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Montagna G,
Morrow M</span><br />
<span class="medgenPMjournal">Ann Surg Oncol</span>
2022 Oct;29(10):6140-6141.
Epub 2022 Aug 11
doi: 10.1245/s10434-022-12405-3.
<span class="bold">PMID: </span><a href="/pubmed/35953742" target="_blank">35953742</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33993211">Management of the axilla after neoadjuvant chemotherapy in breast cancer patients.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Boland MR,
Al-Hilli Z</span><br />
<span class="medgenPMjournal">Br J Surg</span>
2021 Jul 23;108(7):748-749.
doi: 10.1093/bjs/znab137.
<span class="bold">PMID: </span><a href="/pubmed/33993211" target="_blank">33993211</a><a href="/pmc/articles/PMC10364851" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33130487">Occult breast cancer: Where are we at?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Ofri A,
Moore K</span><br />
<span class="medgenPMjournal">Breast</span>
2020 Dec;54:211-215.
Epub 2020 Oct 27
doi: 10.1016/j.breast.2020.10.012.
<span class="bold">PMID: </span><a href="/pubmed/33130487" target="_blank">33130487</a><a href="/pmc/articles/PMC7599122" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30845281">Intraoperative assessment of sentinel lymph nodes in early-stage breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Costin AI,
Păun I,
Vârcuş F,
Răcăreanu MM,
Lomaca I,
Costin AG,
Iovan L,
Radu L,
Mihai GM</span><br />
<span class="medgenPMjournal">Rom J Morphol Embryol</span>
2018;59(4):1033-1039.
<span class="bold">PMID: </span><a href="/pubmed/30845281" target="_blank">30845281</a></div>
<div class="nl"><a target="_blank" href="/pubmed/29413659">Axillary Lymph Node Inclusions.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Cimino-Mathews A</span><br />
<span class="medgenPMjournal">Surg Pathol Clin</span>
2018 Mar;11(1):43-59.
Epub 2017 Nov 29
doi: 10.1016/j.path.2017.09.004.
<span class="bold">PMID: </span><a href="/pubmed/29413659" target="_blank">29413659</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Breast%20Carcinoma%20Metastatic%20in%20the%20Lymph%20Nodes%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2487)</a></div><h3 class="subhead">Therapy</h3>
<div class="nl"><a target="_blank" href="/pubmed/38598571">Omitting Axillary Dissection in Breast Cancer with Sentinel-Node Metastases.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">de Boniface J,
Filtenborg Tvedskov T,
Rydén L,
Szulkin R,
Reimer T,
Kühn T,
Kontos M,
Gentilini OD,
Olofsson Bagge R,
Sund M,
Lundstedt D,
Appelgren M,
Ahlgren J,
Norenstedt S,
Celebioglu F,
Sackey H,
Scheel Andersen I,
Hoyer U,
Nyman PF,
Vikhe Patil E,
Wieslander E,
Dahl Nissen H,
Alkner S,
Andersson Y,
Offersen BV,
Bergkvist L,
Frisell J,
Christiansen P;
SENOMAC Trialists Group;
SENOMAC Trialists' Group</span><br />
<span class="medgenPMjournal">N Engl J Med</span>
2024 Apr 4;390(13):1163-1175.
doi: 10.1056/NEJMoa2313487.
<span class="bold">PMID: </span><a href="/pubmed/38598571" target="_blank">38598571</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37733364">Sentinel Lymph Node Biopsy vs No Axillary Surgery in Patients With Small Breast Cancer and Negative Results on Ultrasonography of Axillary Lymph Nodes: The SOUND Randomized Clinical Trial.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Gentilini OD,
Botteri E,
Sangalli C,
Galimberti V,
Porpiglia M,
Agresti R,
Luini A,
Viale G,
Cassano E,
Peradze N,
Toesca A,
Massari G,
Sacchini V,
Munzone E,
Leonardi MC,
Cattadori F,
Di Micco R,
Esposito E,
Sgarella A,
Cattaneo S,
Busani M,
Dessena M,
Bianchi A,
Cretella E,
Ripoll Orts F,
Mueller M,
Tinterri C,
Chahuan Manzur BJ,
Benedetto C,
Veronesi P;
SOUND Trial Group</span><br />
<span class="medgenPMjournal">JAMA Oncol</span>
2023 Nov 1;9(11):1557-1564.
doi: 10.1001/jamaoncol.2023.3759.
<span class="bold">PMID: </span><a href="/pubmed/37733364" target="_blank">37733364</a><a href="/pmc/articles/PMC10514873" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/37471574">Sentinel lymph node biopsy versus axillary lymph node dissection in breast cancer patients undergoing mastectomy with one to two metastatic sentinel lymph nodes: sub-analysis of the SINODAR-ONE multicentre randomized clinical trial and reopening of enrolment.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Tinterri C,
Canavese G,
Gatzemeier W,
Barbieri E,
Bottini A,
Sagona A,
Caraceni G,
Testori A,
Di Maria Grimaldi S,
Dani C,
Boni L,
Bruzzi P,
Fernandes B,
Scorsetti M,
Zambelli A,
Gentile D;
SINODAR-ONE Collaborative Group</span><br />
<span class="medgenPMjournal">Br J Surg</span>
2023 Aug 11;110(9):1143-1152.
doi: 10.1093/bjs/znad215.
<span class="bold">PMID: </span><a href="/pubmed/37471574" target="_blank">37471574</a><a href="/pmc/articles/PMC10492188" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28898379">Effect of Axillary Dissection vs No Axillary Dissection on 10-Year Overall Survival Among Women With Invasive Breast Cancer and Sentinel Node Metastasis: The ACOSOG Z0011 (Alliance) Randomized Clinical Trial.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Giuliano AE,
Ballman KV,
McCall L,
Beitsch PD,
Brennan MB,
Kelemen PR,
Ollila DW,
Hansen NM,
Whitworth PW,
Blumencranz PW,
Leitch AM,
Saha S,
Hunt KK,
Morrow M</span><br />
<span class="medgenPMjournal">JAMA</span>
2017 Sep 12;318(10):918-926.
doi: 10.1001/jama.2017.11470.
<span class="bold">PMID: </span><a href="/pubmed/28898379" target="_blank">28898379</a><a href="/pmc/articles/PMC5672806" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23683750">Sentinel-lymph-node biopsy in patients with breast cancer before and after neoadjuvant chemotherapy (SENTINA): a prospective, multicentre cohort study.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kuehn T,
Bauerfeind I,
Fehm T,
Fleige B,
Hausschild M,
Helms G,
Lebeau A,
Liedtke C,
von Minckwitz G,
Nekljudova V,
Schmatloch S,
Schrenk P,
Staebler A,
Untch M</span><br />
<span class="medgenPMjournal">Lancet Oncol</span>
2013 Jun;14(7):609-18.
Epub 2013 May 15
doi: 10.1016/S1470-2045(13)70166-9.
<span class="bold">PMID: </span><a href="/pubmed/23683750" target="_blank">23683750</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Breast%20Carcinoma%20Metastatic%20in%20the%20Lymph%20Nodes%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1197)</a></div><h3 class="subhead">Prognosis</h3>
<div class="nl"><a target="_blank" href="/pubmed/33982209">New horizons in imaging and surgical assessment of breast cancer lymph node metastasis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Arjmandi F,
Mootz A,
Farr D,
Reddy S,
Dogan B</span><br />
<span class="medgenPMjournal">Breast Cancer Res Treat</span>
2021 Jun;187(2):311-322.
Epub 2021 May 12
doi: 10.1007/s10549-021-06248-x.
<span class="bold">PMID: </span><a href="/pubmed/33982209" target="_blank">33982209</a></div>
<div class="nl"><a target="_blank" href="/pubmed/30845281">Intraoperative assessment of sentinel lymph nodes in early-stage breast cancer.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Costin AI,
Păun I,
Vârcuş F,
Răcăreanu MM,
Lomaca I,
Costin AG,
Iovan L,
Radu L,
Mihai GM</span><br />
<span class="medgenPMjournal">Rom J Morphol Embryol</span>
2018;59(4):1033-1039.
<span class="bold">PMID: </span><a href="/pubmed/30845281" target="_blank">30845281</a></div>
<div class="nl"><a target="_blank" href="/pubmed/28139362">Eight-year follow up result of the OTOASOR trial: The Optimal Treatment Of the Axilla - Surgery Or Radiotherapy after positive sentinel lymph node biopsy in early-stage breast cancer: A randomized, single centre, phase III, non-inferiority trial.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Sávolt Á,
Péley G,
Polgár C,
Udvarhelyi N,
Rubovszky G,
Kovács E,
Győrffy B,
Kásler M,
Mátrai Z</span><br />
<span class="medgenPMjournal">Eur J Surg Oncol</span>
2017 Apr;43(4):672-679.
Epub 2017 Jan 16
doi: 10.1016/j.ejso.2016.12.011.
<span class="bold">PMID: </span><a href="/pubmed/28139362" target="_blank">28139362</a></div>
<div class="nl"><a target="_blank" href="/pubmed/26400157">Axillary Ultrasound in the Management of the Newly Diagnosed Breast Cancer Patient.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Al-Hilli Z,
Hieken TJ,
Boughey JC</span><br />
<span class="medgenPMjournal">Breast J</span>
2015 Nov-Dec;21(6):634-41.
Epub 2015 Sep 24
doi: 10.1111/tbj.12497.
<span class="bold">PMID: </span><a href="/pubmed/26400157" target="_blank">26400157</a></div>
<div class="nl"><a target="_blank" href="/pubmed/23683750">Sentinel-lymph-node biopsy in patients with breast cancer before and after neoadjuvant chemotherapy (SENTINA): a prospective, multicentre cohort study.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Kuehn T,
Bauerfeind I,
Fehm T,
Fleige B,
Hausschild M,
Helms G,
Lebeau A,
Liedtke C,
von Minckwitz G,
Nekljudova V,
Schmatloch S,
Schrenk P,
Staebler A,
Untch M</span><br />
<span class="medgenPMjournal">Lancet Oncol</span>
2013 Jun;14(7):609-18.
Epub 2013 May 15
doi: 10.1016/S1470-2045(13)70166-9.
<span class="bold">PMID: </span><a href="/pubmed/23683750" target="_blank">23683750</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Breast%20Carcinoma%20Metastatic%20in%20the%20Lymph%20Nodes%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (2765)</a></div><h3 class="subhead">Clinical prediction guides</h3>
<div class="nl"><a target="_blank" href="/pubmed/35244929">Epidemiological and anatomopathological profile of breast cancer in the region of North-West of Tunisia.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Mahjoub N,
Ben Salem K,
Mokrani A,
Mansouri H,
Achouri L,
Chraiet N,
Fehri R</span><br />
<span class="medgenPMjournal">Tunis Med</span>
2021 Avril;99(4):441-448.
<span class="bold">PMID: </span><a href="/pubmed/35244929" target="_blank">35244929</a><a href="/pmc/articles/PMC8734481" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33571371">Endosalpingiosis Is Negative for GATA3.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">White MJ,
Vang R,
Argani P,
Cimino-Mathews A</span><br />
<span class="medgenPMjournal">Arch Pathol Lab Med</span>
2021 Nov 1;145(11):1448-1452.
doi: 10.5858/arpa.2020-0359-OA.
<span class="bold">PMID: </span><a href="/pubmed/33571371" target="_blank">33571371</a></div>
<div class="nl"><a target="_blank" href="/pubmed/32043792">Lymph Node Imaging in Patients with Primary Breast Cancer: Concurrent Diagnostic Tools.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Marino MA,
Avendano D,
Zapata P,
Riedl CC,
Pinker K</span><br />
<span class="medgenPMjournal">Oncologist</span>
2020 Feb;25(2):e231-e242.
Epub 2019 Oct 14
doi: 10.1634/theoncologist.2019-0427.
<span class="bold">PMID: </span><a href="/pubmed/32043792" target="_blank">32043792</a><a href="/pmc/articles/PMC7011661" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/26055316">Ratio and log odds of positive lymph nodes in breast cancer patients with mastectomy.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Chen LJ,
Chung KP,
Chang YJ,
Chang YJ</span><br />
<span class="medgenPMjournal">Surg Oncol</span>
2015 Sep;24(3):239-47.
Epub 2015 May 19
doi: 10.1016/j.suronc.2015.05.001.
<span class="bold">PMID: </span><a href="/pubmed/26055316" target="_blank">26055316</a></div>
<div class="nl"><a target="_blank" href="/pubmed/22649167">The significance of intramammary lymph nodes in breast cancer: a systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Abdullgaffar B,
Gopal P,
Abdulrahim M,
Ghazi E,
Mohamed E</span><br />
<span class="medgenPMjournal">Int J Surg Pathol</span>
2012 Dec;20(6):555-63.
Epub 2012 May 30
doi: 10.1177/1066896912448425.
<span class="bold">PMID: </span><a href="/pubmed/22649167" target="_blank">22649167</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Breast%20Carcinoma%20Metastatic%20in%20the%20Lymph%20Nodes%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1998)</a></div></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
<div class="portlet_content ln">
<div class="nl"><a target="_blank" href="/pubmed/34652689">Systematic review of synchronous contralateral axillary metastases in breast cancer: really M1 disease?</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Díaz-Roldán J,
Eguía-Larrea M,
Rubio-Sánchez T,
Muñoz-Bellvís L</span><br />
<span class="medgenPMjournal">Breast Cancer</span>
2022 Jan;29(1):9-18.
Epub 2021 Oct 15
doi: 10.1007/s12282-021-01293-2.
<span class="bold">PMID: </span><a href="/pubmed/34652689" target="_blank">34652689</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34508873">A systematic review and meta-analysis of vascularized lymph node transfer for breast cancer-related lymphedema.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Winters H,
Tielemans HJP,
Paulus V,
Hummelink S,
Slater NJ,
Ulrich DJO</span><br />
<span class="medgenPMjournal">J Vasc Surg Venous Lymphat Disord</span>
2022 May;10(3):786-795.e1.
Epub 2021 Sep 8
doi: 10.1016/j.jvsv.2021.08.023.
<span class="bold">PMID: </span><a href="/pubmed/34508873" target="_blank">34508873</a></div>
<div class="nl"><a target="_blank" href="/pubmed/34933868">Evaluation of pathological complete response as surrogate endpoint in neoadjuvant randomised clinical trials of early stage breast cancer: systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Conforti F,
Pala L,
Sala I,
Oriecuia C,
De Pas T,
Specchia C,
Graffeo R,
Pagan E,
Queirolo P,
Pennacchioli E,
Colleoni M,
Viale G,
Bagnardi V,
Gelber RD</span><br />
<span class="medgenPMjournal">BMJ</span>
2021 Dec 21;375:e066381.
doi: 10.1136/bmj-2021-066381.
<span class="bold">PMID: </span><a href="/pubmed/34933868" target="_blank">34933868</a><a href="/pmc/articles/PMC8689398" target="_blank" class="PubMedFree">Free PMC Article</a></div>
<div class="nl"><a target="_blank" href="/pubmed/33819852">Axillary staging in ductal carcinoma in situ with microinvasion: A meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Choi B,
Jegatheeswaran L,
Nakhoul M,
Haria P,
Srivastava R,
Karki S,
Lupi M,
Patel V,
Chakravorty A,
Babu E</span><br />
<span class="medgenPMjournal">Surg Oncol</span>
2021 Jun;37:101557.
Epub 2021 Mar 31
doi: 10.1016/j.suronc.2021.101557.
<span class="bold">PMID: </span><a href="/pubmed/33819852" target="_blank">33819852</a></div>
<div class="nl"><a target="_blank" href="/pubmed/22649167">The significance of intramammary lymph nodes in breast cancer: a systematic review and meta-analysis.</a></div>
<div class="portlet_content ln"><span class="medgenPMauthor">Abdullgaffar B,
Gopal P,
Abdulrahim M,
Ghazi E,
Mohamed E</span><br />
<span class="medgenPMjournal">Int J Surg Pathol</span>
2012 Dec;20(6):555-63.
Epub 2012 May 30
doi: 10.1177/1066896912448425.
<span class="bold">PMID: </span><a href="/pubmed/22649167" target="_blank">22649167</a></div>
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Breast%20Carcinoma%20Metastatic%20in%20the%20Lymph%20Nodes%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (45)</a></div></div>
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