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<!--
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UID=1632671
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ConceptID=C4552011
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Gonadotropin deficiency</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1632671</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4552011</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Gonadotropin insufficiency</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0008213">HP:0008213</a></td></tr>
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<tr><td>Orphanet:</td>
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<td><a target="_blank" title="Orphanet: The portal for rare diseases and orphan drugs" href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=181387">ORPHA181387</a></td></tr></tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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||
<div class="portlet_content ln">A reduced ability to secrete gonadotropins, which are protein hormones secreted by gonadotrope cells of the anterior pituitary gland, including the hormones follitropin (FSH) and luteinizing hormone (LH). [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="TLline">Gonadotropin deficiency</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/892343" ref="tree=MeSH" title="MedGen record for Morphological central nervous system abnormality">Morphological central nervous system abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/866738" ref="tree=MeSH" title="MedGen record for Abnormal brain morphology">Abnormal brain morphology</a></span><ul><li><span class="TLline"><a href="/medgen/1843446" ref="tree=MeSH" title="MedGen record for Abnormal pituitary gland morphology">Abnormal pituitary gland morphology</a></span><ul><li><span class="TLline"><a href="/medgen/892315" ref="tree=MeSH" title="MedGen record for Abnormality of the anterior pituitary">Abnormality of the anterior pituitary</a></span><ul><li><span class="TLline"><a href="/medgen/9386" ref="tree=MeSH" title="MedGen record for Hypopituitarism">Hypopituitarism</a></span><ul><li><span class="TLline"><a href="/medgen/871333" ref="tree=MeSH" title="MedGen record for Anterior hypopituitarism">Anterior hypopituitarism</a></span><ul><li><span class="matched_ds">Gonadotropin deficiency</span><ul><li><span class="TLline"><a href="/medgen/394313" ref="tree=MeSH" title="MedGen record for ANE syndrome">ANE syndrome</a></span></li><li><span class="TLline"><a href="/medgen/347798" ref="tree=MeSH" title="MedGen record for Ataxia-hypogonadism-choroidal dystrophy syndrome">Ataxia-hypogonadism-choroidal dystrophy syndrome</a></span></li><li><span class="TLline"><a href="/medgen/156019" ref="tree=MeSH" title="MedGen record for Bardet-Biedl syndrome">Bardet-Biedl syndrome</a></span><ul><li><span class="TLline"><a href="/medgen/422452" ref="tree=MeSH" title="MedGen record for Bardet-Biedl syndrome 1">Bardet-Biedl syndrome 1</a></span></li><li><span class="TLline"><a href="/medgen/422453" ref="tree=MeSH" title="MedGen record for Bardet-Biedl syndrome 2">Bardet-Biedl syndrome 2</a></span></li><li><span class="TLline"><a href="/medgen/347179" ref="tree=MeSH" title="MedGen record for Bardet-Biedl syndrome 3">Bardet-Biedl syndrome 3</a></span></li><li><span class="TLline"><a href="/medgen/423627" ref="tree=MeSH" title="MedGen record for Bardet-Biedl syndrome 4">Bardet-Biedl syndrome 4</a></span></li><li><span class="TLline"><a href="/medgen/856141" ref="tree=MeSH" title="MedGen record for Bardet-Biedl syndrome 5">Bardet-Biedl syndrome 5</a></span></li><li><span class="TLline"><a href="/medgen/347610" ref="tree=MeSH" title="MedGen record for Bardet-Biedl syndrome 6">Bardet-Biedl syndrome 6</a></span></li><li><span class="TLline"><a href="/medgen/347180" ref="tree=MeSH" title="MedGen record for Bardet-Biedl syndrome 7">Bardet-Biedl syndrome 7</a></span></li><li><span class="TLline"><a href="/medgen/347181" ref="tree=MeSH" title="MedGen record for Bardet-Biedl syndrome 8">Bardet-Biedl syndrome 8</a></span></li><li><span class="TLline"><a href="/medgen/347182" ref="tree=MeSH" title="MedGen record for Bardet-Biedl syndrome 9">Bardet-Biedl syndrome 9</a></span></li><li><span class="TLline"><a href="/medgen/347909" ref="tree=MeSH" title="MedGen record for Bardet-Biedl syndrome 10">Bardet-Biedl syndrome 10</a></span></li><li><span class="TLline"><a href="/medgen/395295" ref="tree=MeSH" title="MedGen record for Bardet-Biedl syndrome 11">Bardet-Biedl syndrome 11</a></span></li><li><span class="TLline"><a href="/medgen/347910" ref="tree=MeSH" title="MedGen record for Bardet-Biedl syndrome 12">Bardet-Biedl syndrome 12</a></span></li><li><span class="TLline"><a href="/medgen/393032" ref="tree=MeSH" title="MedGen record for Bardet-Biedl syndrome 13">Bardet-Biedl syndrome 13</a></span></li><li><span class="TLline"><a href="/medgen/393033" ref="tree=MeSH" title="MedGen record for Bardet-Biedl syndrome 14">Bardet-Biedl syndrome 14</a></span></li><li><span class="TLline"><a href="/medgen/461477" ref="tree=MeSH" title="MedGen record for Bardet-Biedl syndrome 15">Bardet-Biedl syndrome 15</a></span></li><li><span class="TLline"><a href="/medgen/855172" ref="tree=MeSH" title="MedGen record for Bardet-Biedl syndrome 16">Bardet-Biedl syndrome 16</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/444052" ref="tree=MeSH" title="MedGen record for Brachytelephalangy-dysmorphism-Kallmann syndrome">Brachytelephalangy-dysmorphism-Kallmann syndrome</a></span></li><li><span class="TLline"><a href="/medgen/349137" ref="tree=MeSH" title="MedGen record for Cerebellar ataxia-hypogonadism syndrome">Cerebellar ataxia-hypogonadism syndrome</a></span></li><li><span class="TLline"><a href="/medgen/75567" ref="tree=MeSH" title="MedGen record for CHARGE syndrome">CHARGE syndrome</a></span></li><li><span class="TLline"><a href="/medgen/928748" ref="tree=MeSH" title="MedGen record for Hypogonadotropic hypogonadism-frontoparietal alopecia syndrome">Hypogonadotropic hypogonadism-frontoparietal alopecia syndrome</a></span></li><li><span class="TLline"><a href="/medgen/419479" ref="tree=MeSH" title="MedGen record for Hypogonadotropic hypogonadism-retinitis pigmentosa syndrome">Hypogonadotropic hypogonadism-retinitis pigmentosa syndrome</a></span></li><li><span class="TLline"><a href="/medgen/1663043" ref="tree=MeSH" title="MedGen record for Hypogonadotropic hypogonadism-severe microcephaly-sensorineural hearing loss-dysmorphism syndrome">Hypogonadotropic hypogonadism-severe microcephaly-sensorineural hearing loss-dysmorphism syndrome</a></span></li><li><span class="TLline"><a href="/medgen/957899" ref="tree=MeSH" title="MedGen record for Hyposmia-nasal and ocular hypoplasia-hypogonadotropic hypogonadism syndrome">Hyposmia-nasal and ocular hypoplasia-hypogonadotropic hypogonadism syndrome</a></span></li><li><span class="TLline"><a href="/medgen/928566" ref="tree=MeSH" title="MedGen record for Kallmann syndrome-heart disease syndrome">Kallmann syndrome-heart disease syndrome</a></span></li><li><span class="TLline"><a href="/medgen/44078" ref="tree=MeSH" title="MedGen record for Laurence-Moon syndrome">Laurence-Moon syndrome</a></span></li><li><span class="TLline"><a href="/medgen/1778114" ref="tree=MeSH" title="MedGen record for Martsolf syndrome 1">Martsolf syndrome 1</a></span></li><li><span class="TLline"><a href="/medgen/419697" ref="tree=MeSH" title="MedGen record for Moebius syndrome-axonal neuropathy-hypogonadotropic hypogonadism syndrome">Moebius syndrome-axonal neuropathy-hypogonadotropic hypogonadism syndrome</a></span></li><li><span class="TLline"><a href="/medgen/863698" ref="tree=MeSH" title="MedGen record for Polyendocrine-polyneuropathy syndrome">Polyendocrine-polyneuropathy syndrome</a></span></li><li><span class="TLline"><a href="/medgen/46057" ref="tree=MeSH" title="MedGen record for Prader-Willi syndrome">Prader-Willi syndrome</a></span><ul><li><span class="TLline"><a href="/medgen/1826086" ref="tree=MeSH" title="MedGen record for Prader-Willi syndrome due to imprinting mutation">Prader-Willi syndrome due to imprinting mutation</a></span></li><li><span class="TLline"><a href="/medgen/1826079" ref="tree=MeSH" title="MedGen record for Prader-Willi syndrome due to maternal uniparental disomy of chromosome 15">Prader-Willi syndrome due to maternal uniparental disomy of chromosome 15</a></span></li><li><span class="TLline"><a href="/medgen/1826129" ref="tree=MeSH" title="MedGen record for Prader-Willi syndrome due to paternal 15q11q13 deletion">Prader-Willi syndrome due to paternal 15q11q13 deletion</a></span></li><li><span class="TLline"><a href="/medgen/1826085" ref="tree=MeSH" title="MedGen record for Prader-Willi syndrome due to translocation">Prader-Willi syndrome due to translocation</a></span></li></ul></li><li><span class="TLline"><a href="/medgen/83337" ref="tree=MeSH" title="MedGen record for Woodhouse-Sakati syndrome">Woodhouse-Sakati syndrome</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_75567"><div><strong>CHARGE syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>75567</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0265354</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">CHD7 disorder encompasses the entire phenotypic spectrum of heterozygous CHD7 pathogenic variants that includes CHARGE syndrome as well as subsets of features that comprise the CHARGE syndrome phenotype. The mnemonic CHARGE syndrome, introduced in the premolecular era, stands for coloboma, heart defect, choanal atresia, retarded growth and development, genital hypoplasia, ear anomalies (including deafness). Following the identification of the genetic cause of CHD7 disorder, the phenotypic spectrum expanded to include cranial nerve anomalies, vestibular defects, cleft lip and/or palate, hypothyroidism, tracheoesophageal anomalies, brain anomalies, seizures, and renal anomalies. Life expectancy highly depends on the severity of manifestations; mortality can be high in the first few years when severe birth defects (particularly complex heart defects) are present and often complicated by airway and feeding issues. In childhood, adolescence, and adulthood, decreased life expectancy is likely related to a combination of residual heart defects, infections, aspiration or choking, respiratory issues including obstructive and central apnea, and possibly seizures. Despite these complications, the life expectancy for many individuals can be normal.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/75567">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_335111"><div><strong>Hartsfield-Bixler-Demyer syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>335111</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1845146</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Congenital Abnormality</dd></dl></div></div></div>
|
||
<div class="spaceAbove">FGFR1-related Hartsfield syndrome comprises two core features: holoprosencephaly (HPE) spectrum disorder and ectrodactyly spectrum disorder. HPE spectrum disorder, resulting from failed or incomplete forebrain division early in gestation, includes alobar, semilobar, or lobar HPE. Other observed midline brain malformations include corpus callosum agenesis, absent septum pellucidum, absent olfactory bulbs and tracts, and vermian hypoplasia. Other findings associated with the HPE spectrum such as craniofacial dysmorphism, neurologic issues (developmental delay, spasticity, seizures, hypothalamic dysfunction), feeding problems, and endocrine issues (hypogonadotropic hypogonadism and central insipidus diabetes) are common. Ectrodactyly spectrum disorders are unilateral or bilateral malformations of the hands and/or feet characterized by a median cleft of hand or foot due to absence of the longitudinal central rays (also called split-hand/foot malformation). The number of digits on the right and left can vary. Polydactyly and syndactyly can also be seen.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/335111">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_341863"><div><strong>Obesity due to pro-opiomelanocortin deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>341863</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1857854</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Early-onset obesity with adrenal insuficiency and red hair (OBAIRH) is an autosomal recessive endocrine disorder characterized by early-onset obesity due to severe hyperphagia, pigmentary abnormalities, mainly pale skin and red hair, and secondary hypocortisolism. In the neonatal period, affected individuals are prone to hypoglycemia, hyperbilirubinemia, and cholestasis that may result in death if not treated. The disorder results from mutation in the POMC gene, which encodes a preproprotein that is processed into a range of bioactive peptides, including alpha-melanocyte-stimulating hormone (MSH) and ACTH (summary by Kuhnen et al., 2016 and Clement et al., 2008).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/341863">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_369694"><div><strong>Brain-lung-thyroid syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>369694</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1970269</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">NKX2-1-related disorders range from benign hereditary chorea (BHC) to choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress syndrome (also known as brain-lung-thyroid syndrome). Childhood-onset chorea, the hallmark feature of NKX2-1-related disorders, may or may not be associated with pulmonary disease or congenital hypothyroidism. Age of onset of chorea varies from early infancy (most commonly) to late childhood or adolescence and may progress into the second decade, after which it remains static or (rarely) remits. Pulmonary disease, the second most common manifestation, can include respiratory distress syndrome in neonates, interstitial lung disease in young children, and pulmonary fibrosis in older individuals. The risk for pulmonary carcinoma is increased in young adults with NKX2-1-related disorders. Thyroid dysfunction, occurring as a result of thyroid dysgenesis, can present as congenital or compensated hypothyroidism. In one review, 50% of affected individuals had the full brain-lung-thyroid syndrome, 30% had brain and thyroid involvement only, and 13% had chorea only.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/369694">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_483740"><div><strong>Non-acquired combined pituitary hormone deficiency with spine abnormalities</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>483740</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3489787</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Combined pituitary hormone deficiency-3 (CPHD3) is an autosomal recessive disorder characterized by hypopituitarism with structural anterior pituitary defects and cervical abnormalities with or without restricted neck rotation. Some patients have sensorineural hearing loss (summary by Rajab et al., 2008). For a discussion of phenotypic and genetic heterogeneity of combined pituitary hormone deficiency, see CPHD1 (613038).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/483740">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_369694" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Brain-lung-thyroid syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_75567" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">CHARGE syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_335111" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hartsfield-Bixler-Demyer syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_483740" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Non-acquired combined pituitary hormone deficiency with spine abnormalities</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_341863" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Obesity due to pro-opiomelanocortin deficiency</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37737473">Clinical management of nonobstructive azoospermia: An update.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Takeshima T,
|
||
Karibe J,
|
||
Saito T,
|
||
Kuroda S,
|
||
Komeya M,
|
||
Uemura H,
|
||
Yumura Y</span><br />
|
||
<span class="medgenPMjournal">Int J Urol</span>
|
||
2024 Jan;31(1):17-24.
|
||
Epub 2023 Sep 22
|
||
doi: 10.1111/iju.15301.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37737473" target="_blank">37737473</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24683947">Treatment of hypogonadism in males.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Watson S,
|
||
Fuqua JS,
|
||
Lee PA</span><br />
|
||
<span class="medgenPMjournal">Pediatr Endocrinol Rev</span>
|
||
2014 Feb;11 Suppl 2:230-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24683947" target="_blank">24683947</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22541999">Male acquired hypogonadotropic hypogonadism: diagnosis and treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Salenave S,
|
||
Trabado S,
|
||
Maione L,
|
||
Brailly-Tabard S,
|
||
Young J</span><br />
|
||
<span class="medgenPMjournal">Ann Endocrinol (Paris)</span>
|
||
2012 Apr;73(2):141-6.
|
||
Epub 2012 Apr 25
|
||
doi: 10.1016/j.ando.2012.03.040.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22541999" target="_blank">22541999</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22gonadotropin%20deficiency%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (27)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37737473">Clinical management of nonobstructive azoospermia: An update.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Takeshima T,
|
||
Karibe J,
|
||
Saito T,
|
||
Kuroda S,
|
||
Komeya M,
|
||
Uemura H,
|
||
Yumura Y</span><br />
|
||
<span class="medgenPMjournal">Int J Urol</span>
|
||
2024 Jan;31(1):17-24.
|
||
Epub 2023 Sep 22
|
||
doi: 10.1111/iju.15301.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37737473" target="_blank">37737473</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23167686">Mechanism of human chorionic gonadotrophin-mediated immunomodulation in pregnancy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bansal AS,
|
||
Bora SA,
|
||
Saso S,
|
||
Smith JR,
|
||
Johnson MR,
|
||
Thum MY</span><br />
|
||
<span class="medgenPMjournal">Expert Rev Clin Immunol</span>
|
||
2012 Nov;8(8):747-53.
|
||
doi: 10.1586/eci.12.77.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23167686" target="_blank">23167686</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17077946">Hypopituitarism.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ascoli P,
|
||
Cavagnini F</span><br />
|
||
<span class="medgenPMjournal">Pituitary</span>
|
||
2006;9(4):335-42.
|
||
doi: 10.1007/s11102-006-0416-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17077946" target="_blank">17077946</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7705320">Male infertility.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Baker HW</span><br />
|
||
<span class="medgenPMjournal">Endocrinol Metab Clin North Am</span>
|
||
1994 Dec;23(4):783-93.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7705320" target="_blank">7705320</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/2889818">Isolated gonadotropin deficiency in boys: clinical characteristics and growth.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Van Dop C,
|
||
Burstein S,
|
||
Conte FA,
|
||
Grumbach MM</span><br />
|
||
<span class="medgenPMjournal">J Pediatr</span>
|
||
1987 Nov;111(5):684-92.
|
||
doi: 10.1016/s0022-3476(87)80243-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/2889818" target="_blank">2889818</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Gonadotropin%20deficiency%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (104)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34238452">Neuroendocrine manifestations of Langerhans cell histiocytosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yavropoulou MP,
|
||
Tsoli M,
|
||
Kaltsas G</span><br />
|
||
<span class="medgenPMjournal">Handb Clin Neurol</span>
|
||
2021;181:127-135.
|
||
doi: 10.1016/B978-0-12-820683-6.00009-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34238452" target="_blank">34238452</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32748610">Delayed puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Butler G,
|
||
Purushothaman P</span><br />
|
||
<span class="medgenPMjournal">Minerva Pediatr</span>
|
||
2020 Dec;72(6):484-490.
|
||
Epub 2020 Aug 4
|
||
doi: 10.23736/S0026-4946.20.05968-X.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32748610" target="_blank">32748610</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24716396">Aromatase excess syndrome: a rare autosomal dominant disorder leading to pre- or peri-pubertal onset gynecomastia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fukami M,
|
||
Miyado M,
|
||
Nagasaki K,
|
||
Shozu M,
|
||
Ogata T</span><br />
|
||
<span class="medgenPMjournal">Pediatr Endocrinol Rev</span>
|
||
2014 Mar;11(3):298-305.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24716396" target="_blank">24716396</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17077946">Hypopituitarism.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ascoli P,
|
||
Cavagnini F</span><br />
|
||
<span class="medgenPMjournal">Pituitary</span>
|
||
2006;9(4):335-42.
|
||
doi: 10.1007/s11102-006-0416-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17077946" target="_blank">17077946</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7705320">Male infertility.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Baker HW</span><br />
|
||
<span class="medgenPMjournal">Endocrinol Metab Clin North Am</span>
|
||
1994 Dec;23(4):783-93.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7705320" target="_blank">7705320</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Gonadotropin%20deficiency%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (136)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/27697201">Clinical Applications of Gonadotropins in the Male.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ulloa-Aguirre A,
|
||
Lira-Albarrán S</span><br />
|
||
<span class="medgenPMjournal">Prog Mol Biol Transl Sci</span>
|
||
2016;143:121-174.
|
||
Epub 2016 Sep 13
|
||
doi: 10.1016/bs.pmbts.2016.08.003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27697201" target="_blank">27697201</a></div>
|
||
|
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<div class="nl"><a target="_blank" href="/pubmed/24716396">Aromatase excess syndrome: a rare autosomal dominant disorder leading to pre- or peri-pubertal onset gynecomastia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Fukami M,
|
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Miyado M,
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Nagasaki K,
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Shozu M,
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Ogata T</span><br />
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<span class="medgenPMjournal">Pediatr Endocrinol Rev</span>
|
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2014 Mar;11(3):298-305.
|
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<span class="bold">PMID: </span><a href="/pubmed/24716396" target="_blank">24716396</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23775378">Male reproductive endocrinology: when to replace gonadotropins.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Trussell JC</span><br />
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<span class="medgenPMjournal">Semin Reprod Med</span>
|
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2013 Jul;31(4):237-44.
|
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Epub 2013 Jun 17
|
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doi: 10.1055/s-0033-1345270.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23775378" target="_blank">23775378</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17077946">Hypopituitarism.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ascoli P,
|
||
Cavagnini F</span><br />
|
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<span class="medgenPMjournal">Pituitary</span>
|
||
2006;9(4):335-42.
|
||
doi: 10.1007/s11102-006-0416-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17077946" target="_blank">17077946</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/4586101">Isolated gonadotropin deficiency. A heterogenous syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Spitz IM,
|
||
Diamant Y,
|
||
Rosen E,
|
||
Bell J,
|
||
David MB,
|
||
Polishuk W,
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||
Rabinowitz D</span><br />
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<span class="medgenPMjournal">N Engl J Med</span>
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1974 Jan 3;290(1):10-5.
|
||
doi: 10.1056/NEJM197401032900103.
|
||
<span class="bold">PMID: </span><a href="/pubmed/4586101" target="_blank">4586101</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Gonadotropin%20deficiency%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (116)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/38715016">Partial hypopituitarism with ACTH deficiency as the main manifestation as a complication of hemorrhagic fever with renal syndrome.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shi S,
|
||
Zhang A,
|
||
Zhang J,
|
||
Xu S</span><br />
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||
<span class="medgenPMjournal">BMC Endocr Disord</span>
|
||
2024 May 7;24(1):61.
|
||
doi: 10.1186/s12902-024-01587-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38715016" target="_blank">38715016</a><a href="/pmc/articles/PMC11075197" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37737473">Clinical management of nonobstructive azoospermia: An update.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Takeshima T,
|
||
Karibe J,
|
||
Saito T,
|
||
Kuroda S,
|
||
Komeya M,
|
||
Uemura H,
|
||
Yumura Y</span><br />
|
||
<span class="medgenPMjournal">Int J Urol</span>
|
||
2024 Jan;31(1):17-24.
|
||
Epub 2023 Sep 22
|
||
doi: 10.1111/iju.15301.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37737473" target="_blank">37737473</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35358314">Reproductive Phenotypes in Men With Acquired or Congenital Hypogonadotropic Hypogonadism: A Comparative Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Maione L,
|
||
Sarfati J,
|
||
Gonfroy-Leymarie C,
|
||
Salenave S,
|
||
Brailly-Tabard S,
|
||
Chanson P,
|
||
Trabado S,
|
||
Kaiser UB,
|
||
Young J</span><br />
|
||
<span class="medgenPMjournal">J Clin Endocrinol Metab</span>
|
||
2022 Jun 16;107(7):e2812-e2824.
|
||
doi: 10.1210/clinem/dgac194.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35358314" target="_blank">35358314</a><a href="/pmc/articles/PMC10310981" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32748610">Delayed puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Butler G,
|
||
Purushothaman P</span><br />
|
||
<span class="medgenPMjournal">Minerva Pediatr</span>
|
||
2020 Dec;72(6):484-490.
|
||
Epub 2020 Aug 4
|
||
doi: 10.23736/S0026-4946.20.05968-X.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32748610" target="_blank">32748610</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16423605">Evaluation of the buserelin stimulation test in diagnosing gonadotropin deficiency in males with delayed puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wilson DA,
|
||
Hofman PL,
|
||
Miles HL,
|
||
Unwin KE,
|
||
McGrail CE,
|
||
Cutfield WS</span><br />
|
||
<span class="medgenPMjournal">J Pediatr</span>
|
||
2006 Jan;148(1):89-94.
|
||
doi: 10.1016/j.jpeds.2005.08.045.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16423605" target="_blank">16423605</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Gonadotropin%20deficiency%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (56)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37737473">Clinical management of nonobstructive azoospermia: An update.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Takeshima T,
|
||
Karibe J,
|
||
Saito T,
|
||
Kuroda S,
|
||
Komeya M,
|
||
Uemura H,
|
||
Yumura Y</span><br />
|
||
<span class="medgenPMjournal">Int J Urol</span>
|
||
2024 Jan;31(1):17-24.
|
||
Epub 2023 Sep 22
|
||
doi: 10.1111/iju.15301.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37737473" target="_blank">37737473</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35358314">Reproductive Phenotypes in Men With Acquired or Congenital Hypogonadotropic Hypogonadism: A Comparative Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Maione L,
|
||
Sarfati J,
|
||
Gonfroy-Leymarie C,
|
||
Salenave S,
|
||
Brailly-Tabard S,
|
||
Chanson P,
|
||
Trabado S,
|
||
Kaiser UB,
|
||
Young J</span><br />
|
||
<span class="medgenPMjournal">J Clin Endocrinol Metab</span>
|
||
2022 Jun 16;107(7):e2812-e2824.
|
||
doi: 10.1210/clinem/dgac194.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35358314" target="_blank">35358314</a><a href="/pmc/articles/PMC10310981" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32748610">Delayed puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Butler G,
|
||
Purushothaman P</span><br />
|
||
<span class="medgenPMjournal">Minerva Pediatr</span>
|
||
2020 Dec;72(6):484-490.
|
||
Epub 2020 Aug 4
|
||
doi: 10.23736/S0026-4946.20.05968-X.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32748610" target="_blank">32748610</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18987493">The role of SOX2 in hypogonadotropic hypogonadism.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tziaferi V,
|
||
Kelberman D,
|
||
Dattani MT</span><br />
|
||
<span class="medgenPMjournal">Sex Dev</span>
|
||
2008;2(4-5):194-9.
|
||
Epub 2008 Nov 5
|
||
doi: 10.1159/000152035.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18987493" target="_blank">18987493</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16423605">Evaluation of the buserelin stimulation test in diagnosing gonadotropin deficiency in males with delayed puberty.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wilson DA,
|
||
Hofman PL,
|
||
Miles HL,
|
||
Unwin KE,
|
||
McGrail CE,
|
||
Cutfield WS</span><br />
|
||
<span class="medgenPMjournal">J Pediatr</span>
|
||
2006 Jan;148(1):89-94.
|
||
doi: 10.1016/j.jpeds.2005.08.045.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16423605" target="_blank">16423605</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Gonadotropin%20deficiency%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (77)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/39445789">Efficacy of Gonadotropin Treatment for Induction of Spermatogenesis in Men With Pathologic Gonadotropin Deficiency: A Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Muir CA,
|
||
Zhang T,
|
||
Jayadev V,
|
||
Conway AJ,
|
||
Handelsman DJ</span><br />
|
||
<span class="medgenPMjournal">Clin Endocrinol (Oxf)</span>
|
||
2025 Feb;102(2):167-177.
|
||
Epub 2024 Oct 24
|
||
doi: 10.1111/cen.15151.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39445789" target="_blank">39445789</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Gonadotropin%20deficiency%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
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|
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|
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|
||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
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|
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|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Expert=181387" target="_blank">Orphanet</a></li><li><a href="https://clinicaltrials.gov/search?cond=Gonadotropin%20deficiency" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22gonadotropin%20deficiency%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Gonadotropin%20deficiency%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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<div class="portlet_content ln"><ul><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Gonadotropin%20deficiency" target="_blank">MedlinePlus</a></li></ul></div>
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<a href="/pubmed?term=Gonadotropin%20deficiency%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=2&linkpostotal=2" target="_blank">Reviews in PubMed</a>
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