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<!--
|
||
UID=154303
|
||
ConceptID=C0553730
|
||
-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Chondrocalcinosis</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>154303</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0553730</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Calcium Pyrophosphate Deposition Disease; Chondrocalcinoses; Pseudogout</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Pseudogout (201637001); Chondrocalcinosis due to pyrophosphate crystals (201637001); Calcium pyrophosphate arthritis and periarthritis (239832006); CPPD - Calcium pyrophosphate deposition disease (239832006); CPDD - Calcium pyrophosphate deposition disease (239832006); Calcium pyrophosphate deposition disease (239832006); Chondrocalcinosis (239838005)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0000934">HP:0000934</a></td></tr>
|
||
<tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0001314" target="_blank">MONDO:0001314</a></td></tr>
|
||
</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Radiographic evidence of articular calcification that represent calcium pyrophosphate depositions in soft tissue surrounding joints and at the insertions of tendons near joints (Entheses/Sharpey fibers) . [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0553730[DISCUI]&test_type=Clinical" ref="ncbi_uid=154303">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet Vcolor" title="ClinVar"><a target="_blank" href="/clinvar?LinkName=medgen_clinvar&from_uid=154303" ref="ncbi_uid=154303">V</a></span></span><span class="TLline">Chondrocalcinosis</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/1763488" ref="tree=MeSH" title="MedGen record for Abnormality of the musculoskeletal system">Abnormality of the musculoskeletal system</a></span><ul><li><span class="TLline"><a href="/medgen/871127" ref="tree=MeSH" title="MedGen record for Abnormality of connective tissue">Abnormality of connective tissue</a></span><ul><li><span class="TLline"><a href="/medgen/892797" ref="tree=MeSH" title="MedGen record for Abnormal Sharpey fiber morphology">Abnormal Sharpey fiber morphology</a></span><ul><li><span class="matched_ds">Chondrocalcinosis</span><ul><li><span class="TLline"><a href="/medgen/870801" ref="tree=MeSH" title="MedGen record for Polyarticular chondrocalcinosis">Polyarticular chondrocalcinosis</a></span></li><li><span class="TLline"><a href="/medgen/592677" ref="tree=MeSH" title="MedGen record for Rotator cuff tear arthropathy">Rotator cuff tear arthropathy</a></span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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</div>
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<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_42426"><div><strong>Wilson disease</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>42426</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0019202</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Wilson disease is a disorder of copper metabolism that, when untreated, can present with hepatic, neurologic, or psychiatric disturbances – or a combination of these – in individuals ages three years to older than 70 years. Manifestations in untreated individuals vary among and within families. Liver disease can include recurrent jaundice, simple acute self-limited hepatitis-like illness, autoimmune-type hepatitis, fulminant hepatic failure, or chronic liver disease. Neurologic presentations can include dysarthria, movement disorders (tremors, involuntary movements, chorea, choreoathetosis), dystonia (mask-like facies, rigidity, gait disturbance, pseudobulbar involvement), dysautonomia, seizures, sleep disorders, or insomnia. Psychiatric disturbances can include depression, bipolar disorder / bipolar spectrum disorder, neurotic behaviors, personality changes, or psychosis. Other multisystem involvement can include the eye (Kayser-Fleischer rings), hemolytic anemia, the kidneys, the endocrine glands, and the heart.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/42426">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_120636"><div><strong>Adult hypophosphatasia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>120636</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0268413</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Hypophosphatasia is characterized by defective mineralization of growing or remodeling bone, with or without root-intact tooth loss, in the presence of low activity of serum and bone alkaline phosphatase. Clinical features range from stillbirth without mineralized bone at the severe end to pathologic fractures of the lower extremities in later adulthood at the mild end. While the disease spectrum is a continuum, seven clinical forms of hypophosphatasia are usually recognized based on age at diagnosis and severity of features: Perinatal (severe): Characterized by pulmonary insufficiency and hypercalcemia Perinatal (benign): Prenatal skeletal manifestations that slowly resolve into one of the milder forms Infantile: Onset between birth and age six months of clinical features of rickets without elevated serum alkaline phosphatase activity Severe childhood (juvenile): Variable presenting features progressing to rickets Mild childhood: Low bone mineral density for age, increased risk of fracture, and premature loss of primary teeth with intact roots Adult: Characterized by stress fractures and pseudofractures of the lower extremities in middle age, sometimes associated with early loss of adult dentition Odontohypophosphatasia: Characterized by premature exfoliation of primary teeth and/or severe dental caries without skeletal manifestations</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/120636">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_75681"><div><strong>Familial hypokalemia-hypomagnesemia</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>75681</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0268450</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Gitelman syndrome (GTLMNS) is an autosomal recessive renal tubular salt-wasting disorder characterized by hypokalemic metabolic alkalosis with hypomagnesemia and hypocalciuria. It is the most common renal tubular disorder among Caucasians (prevalence of 1 in 40,000). Most patients have onset of symptoms as adults, but some present in childhood. Clinical features include transient periods of muscle weakness and tetany, abdominal pains, and chondrocalcinosis (summary by Glaudemans et al., 2012). Gitelman syndrome is sometimes referred to as a mild variant of classic Bartter syndrome (607364). For a discussion of genetic heterogeneity of Bartter syndrome, see 607364.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/75681">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_226942"><div><strong>Deficiency of hyaluronoglucosaminidase</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>226942</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1291490</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Mucopolysaccharidosis type IX (MPS9) is a rare progressive lysosomal storage disorder caused by the deficiency of the enzyme hyaluronoglucosaminidase-1, which degrades hyaluronan (summary by Imundo et al., 2011).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/226942">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_322173"><div><strong>Familial hypocalciuric hypercalcemia 3</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>322173</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1833372</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Any familial hypocalciuric hypercalcemia in which the cause of the disease is a mutation in the AP2S1 gene.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/322173">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_331527"><div><strong>Chondrocalcinosis 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>331527</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1833499</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/331527">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_320542"><div><strong>Renal hypomagnesemia 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>320542</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1835171</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Autosomal dominant renal hypomagnesium wasting (HOMG2) is characterized by hypomagnesemia due to renal magnesium loss and is associated with hypocalciuria. Patients may have convulsions and muscle cramps, but they may also be asymptomatic except for the development of chondrocalcinosis at an adult age (summary by Knoers, 2009 and de Baaij et al., 2015). For a discussion of genetic heterogeneity of renal hypomagnesemia, see 602014.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/320542">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_374447"><div><strong>Familial hypocalciuric hypercalcemia 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>374447</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1840347</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Familial hypocalciuric hypercalcemia type II (HHC2) is an autosomal dominant disorder characterized by lifelong elevations of serum calcium concentrations with low urinary calcium excretion and normal circulating parathyroid hormone concentrations in most patients. Patients are generally asymptomatic (summary by Nesbit et al., 2013). For a general phenotypic description and a discussion of genetic heterogeneity of hypocalciuric hypercalcemia, see HHC1 (145980).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/374447">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_343428"><div><strong>Bartter disease type 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>343428</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1855849</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Bartter syndrome refers to a group of disorders that are unified by autosomal recessive transmission of impaired salt reabsorption in the thick ascending loop of Henle with pronounced salt wasting, hypokalemic metabolic alkalosis, and hypercalciuria. Clinical disease results from defective renal reabsorption of sodium chloride in the thick ascending limb (TAL) of the Henle loop, where 30% of filtered salt is normally reabsorbed (Simon et al., 1997). Patients with antenatal forms of Bartter syndrome typically present with premature birth associated with polyhydramnios and low birth weight and may develop life-threatening dehydration in the neonatal period. Patients with classic Bartter syndrome (see BARTS3, 607364) present later in life and may be sporadically asymptomatic or mildly symptomatic (summary by Simon et al., 1996 and Fremont and Chan, 2012). For a discussion of genetic heterogeneity of Bartter syndrome, see 607364.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/343428">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_355727"><div><strong>Bartter disease type 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>355727</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1866495</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Bartter syndrome refers to a group of disorders that are unified by autosomal recessive transmission of impaired salt reabsorption in the thick ascending loop of Henle with pronounced salt wasting, hypokalemic metabolic alkalosis, and hypercalciuria. Clinical disease results from defective renal reabsorption of sodium chloride in the thick ascending limb (TAL) of the Henle loop, where 30% of filtered salt is normally reabsorbed (Simon et al., 1997). Patients with antenatal forms of Bartter syndrome typically present with premature birth associated with polyhydramnios and low birth weight and may develop life-threatening dehydration in the neonatal period. Patients with classic Bartter syndrome (see BARTS3, 607364) present later in life and may be sporadically asymptomatic or mildly symptomatic (summary by Simon et al., 1996 and Fremont and Chan, 2012). For a discussion of genetic heterogeneity of Bartter syndrome, see 607364.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/355727">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_120636" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Adult hypophosphatasia</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_355727" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Bartter disease type 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_343428" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Bartter disease type 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_331527" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Chondrocalcinosis 1</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_226942" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Deficiency of hyaluronoglucosaminidase</a></div><div class="jig-moreless" data-jigconfig="class: 'moveDown', moreText: 'See full list (10)', lessText: 'Show less', nodeBefore: 0"><span id="clinMore">
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_374447" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial hypocalciuric hypercalcemia 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_322173" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial hypocalciuric hypercalcemia 3</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_75681" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial hypokalemia-hypomagnesemia</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_320542" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Renal hypomagnesemia 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_42426" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Wilson disease</a></div></span></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34075537">The role of Interleukin-1 receptor antagonist as a treatment option in calcium pyrophosphate crystal deposition disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Altomare A,
|
||
Corrado A,
|
||
Maruotti N,
|
||
Cici D,
|
||
Cantatore FP</span><br />
|
||
<span class="medgenPMjournal">Mol Biol Rep</span>
|
||
2021 May;48(5):4789-4796.
|
||
Epub 2021 Jun 1
|
||
doi: 10.1007/s11033-021-06457-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34075537" target="_blank">34075537</a><a href="/pmc/articles/PMC8260411" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32072352">Treatment of hypophosphatasia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Simon S,
|
||
Resch H</span><br />
|
||
<span class="medgenPMjournal">Wien Med Wochenschr</span>
|
||
2020 Apr;170(5-6):112-115.
|
||
Epub 2020 Feb 18
|
||
doi: 10.1007/s10354-020-00736-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/32072352" target="_blank">32072352</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21216817">European League Against Rheumatism recommendations for calcium pyrophosphate deposition. Part I: terminology and diagnosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhang W,
|
||
Doherty M,
|
||
Bardin T,
|
||
Barskova V,
|
||
Guerne PA,
|
||
Jansen TL,
|
||
Leeb BF,
|
||
Perez-Ruiz F,
|
||
Pimentao J,
|
||
Punzi L,
|
||
Richette P,
|
||
Sivera F,
|
||
Uhlig T,
|
||
Watt I,
|
||
Pascual E</span><br />
|
||
<span class="medgenPMjournal">Ann Rheum Dis</span>
|
||
2011 Apr;70(4):563-70.
|
||
Epub 2011 Jan 7
|
||
doi: 10.1136/ard.2010.139105.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21216817" target="_blank">21216817</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22chondrocalcinosis%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (19)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37249457">Hypophosphatasia: from birth to adulthood.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Reis FS,
|
||
Lazaretti-Castro M</span><br />
|
||
<span class="medgenPMjournal">Arch Endocrinol Metab</span>
|
||
2023 May 25;67(5):e000626.
|
||
doi: 10.20945/2359-3997000000626.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37249457" target="_blank">37249457</a><a href="/pmc/articles/PMC10665056" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35672096">Imaging of Crystal Disorders:: Calcium Pyrophosphate Dihydrate Crystal Deposition Disease, Calcium Hydroxyapatite Crystal Deposition Disease and Gout Pathophysiology, Imaging, and Diagnosis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Reijnierse M,
|
||
Schwabl C,
|
||
Klauser A</span><br />
|
||
<span class="medgenPMjournal">Radiol Clin North Am</span>
|
||
2022 Jul;60(4):641-656.
|
||
doi: 10.1016/j.rcl.2022.03.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35672096" target="_blank">35672096</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30054011">Pain after stroke: A review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Delpont B,
|
||
Blanc C,
|
||
Osseby GV,
|
||
Hervieu-Bègue M,
|
||
Giroud M,
|
||
Béjot Y</span><br />
|
||
<span class="medgenPMjournal">Rev Neurol (Paris)</span>
|
||
2018 Dec;174(10):671-674.
|
||
Epub 2018 Jul 24
|
||
doi: 10.1016/j.neurol.2017.11.011.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30054011" target="_blank">30054011</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29759121">Diagnosis and Treatment of Gout and Pseudogout for Everyday Practice.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sidari A,
|
||
Hill E</span><br />
|
||
<span class="medgenPMjournal">Prim Care</span>
|
||
2018 Jun;45(2):213-236.
|
||
doi: 10.1016/j.pop.2018.02.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29759121" target="_blank">29759121</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27355536">Calcium Pyrophosphate Deposition Disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rosenthal AK,
|
||
Ryan LM</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2016 Jun 30;374(26):2575-84.
|
||
doi: 10.1056/NEJMra1511117.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27355536" target="_blank">27355536</a><a href="/pmc/articles/PMC6240444" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Chondrocalcinosis%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (378)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/34623546">Chondrocalcinosis: Advances in Diagnostic Imaging.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sullivan J,
|
||
Pillinger MH,
|
||
Toprover M</span><br />
|
||
<span class="medgenPMjournal">Curr Rheumatol Rep</span>
|
||
2021 Oct 8;23(10):77.
|
||
doi: 10.1007/s11926-021-01044-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34623546" target="_blank">34623546</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29759121">Diagnosis and Treatment of Gout and Pseudogout for Everyday Practice.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sidari A,
|
||
Hill E</span><br />
|
||
<span class="medgenPMjournal">Prim Care</span>
|
||
2018 Jun;45(2):213-236.
|
||
doi: 10.1016/j.pop.2018.02.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29759121" target="_blank">29759121</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27355536">Calcium Pyrophosphate Deposition Disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rosenthal AK,
|
||
Ryan LM</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2016 Jun 30;374(26):2575-84.
|
||
doi: 10.1056/NEJMra1511117.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27355536" target="_blank">27355536</a><a href="/pmc/articles/PMC6240444" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24703345">Imaging in the crystal arthropathies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McQueen FM,
|
||
Doyle A,
|
||
Dalbeth N</span><br />
|
||
<span class="medgenPMjournal">Rheum Dis Clin North Am</span>
|
||
2014 May;40(2):231-49.
|
||
Epub 2014 Feb 20
|
||
doi: 10.1016/j.rdc.2014.01.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24703345" target="_blank">24703345</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/4354552">Pseudogout.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rubinstein HM,
|
||
Shah DM</span><br />
|
||
<span class="medgenPMjournal">Semin Arthritis Rheum</span>
|
||
1972-1973;2(3):259-80.
|
||
doi: 10.1016/0049-0172(72)90011-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/4354552" target="_blank">4354552</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Chondrocalcinosis%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (832)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/30741851">Acute monoarthritis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ellis JM</span><br />
|
||
<span class="medgenPMjournal">JAAPA</span>
|
||
2019 Mar;32(3):25-31.
|
||
doi: 10.1097/01.JAA.0000553379.52389.eb.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30741851" target="_blank">30741851</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29759121">Diagnosis and Treatment of Gout and Pseudogout for Everyday Practice.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sidari A,
|
||
Hill E</span><br />
|
||
<span class="medgenPMjournal">Prim Care</span>
|
||
2018 Jun;45(2):213-236.
|
||
doi: 10.1016/j.pop.2018.02.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29759121" target="_blank">29759121</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29675606">Therapy for CPPD: Options and Evidence.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Andrés M,
|
||
Sivera F,
|
||
Pascual E</span><br />
|
||
<span class="medgenPMjournal">Curr Rheumatol Rep</span>
|
||
2018 Apr 19;20(6):31.
|
||
doi: 10.1007/s11926-018-0739-z.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29675606" target="_blank">29675606</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27355536">Calcium Pyrophosphate Deposition Disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rosenthal AK,
|
||
Ryan LM</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
2016 Jun 30;374(26):2575-84.
|
||
doi: 10.1056/NEJMra1511117.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27355536" target="_blank">27355536</a><a href="/pmc/articles/PMC6240444" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/54937">Radionuclide joint imaging.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Hoffer PB,
|
||
Genant HK</span><br />
|
||
<span class="medgenPMjournal">Semin Nucl Med</span>
|
||
1976 Jan;6(1):121-37.
|
||
doi: 10.1016/s0001-2998(76)80041-4.
|
||
<span class="bold">PMID: </span><a href="/pubmed/54937" target="_blank">54937</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Chondrocalcinosis%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (285)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37249457">Hypophosphatasia: from birth to adulthood.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Reis FS,
|
||
Lazaretti-Castro M</span><br />
|
||
<span class="medgenPMjournal">Arch Endocrinol Metab</span>
|
||
2023 May 25;67(5):e000626.
|
||
doi: 10.20945/2359-3997000000626.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37249457" target="_blank">37249457</a><a href="/pmc/articles/PMC10665056" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28003083">Gitelman syndrome: consensus and guidance from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Blanchard A,
|
||
Bockenhauer D,
|
||
Bolignano D,
|
||
Calò LA,
|
||
Cosyns E,
|
||
Devuyst O,
|
||
Ellison DH,
|
||
Karet Frankl FE,
|
||
Knoers NV,
|
||
Konrad M,
|
||
Lin SH,
|
||
Vargas-Poussou R</span><br />
|
||
<span class="medgenPMjournal">Kidney Int</span>
|
||
2017 Jan;91(1):24-33.
|
||
doi: 10.1016/j.kint.2016.09.046.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28003083" target="_blank">28003083</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24703345">Imaging in the crystal arthropathies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McQueen FM,
|
||
Doyle A,
|
||
Dalbeth N</span><br />
|
||
<span class="medgenPMjournal">Rheum Dis Clin North Am</span>
|
||
2014 May;40(2):231-49.
|
||
Epub 2014 Feb 20
|
||
doi: 10.1016/j.rdc.2014.01.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24703345" target="_blank">24703345</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7656347">Crystal arthritis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Poór G</span><br />
|
||
<span class="medgenPMjournal">Baillieres Clin Rheumatol</span>
|
||
1995 May;9(2):397-406.
|
||
doi: 10.1016/s0950-3579(05)80197-9.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7656347" target="_blank">7656347</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/227047">Pyrophosphate arthropathy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bjelle A</span><br />
|
||
<span class="medgenPMjournal">Scand J Rheumatol</span>
|
||
1979;8(3):145-53.
|
||
doi: 10.3109/03009747909114447.
|
||
<span class="bold">PMID: </span><a href="/pubmed/227047" target="_blank">227047</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Chondrocalcinosis%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (170)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39059972">Current Role of Conventional Radiology in Rheumatology.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Arrigoni F,
|
||
Daffinà J,
|
||
Barile A</span><br />
|
||
<span class="medgenPMjournal">Radiol Clin North Am</span>
|
||
2024 Sep;62(5):799-807.
|
||
Epub 2024 Apr 23
|
||
doi: 10.1016/j.rcl.2024.03.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39059972" target="_blank">39059972</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37495237">The 2023 ACR/EULAR classification criteria for calcium pyrophosphate deposition disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Abhishek A,
|
||
Tedeschi SK,
|
||
Pascart T,
|
||
Latourte A,
|
||
Dalbeth N,
|
||
Neogi T,
|
||
Fuller A,
|
||
Rosenthal A,
|
||
Becce F,
|
||
Bardin T,
|
||
Ea HK,
|
||
Filippou G,
|
||
Fitzgerald J,
|
||
Iagnocco A,
|
||
Lioté F,
|
||
McCarthy GM,
|
||
Ramonda R,
|
||
Richette P,
|
||
Sivera F,
|
||
Andrés M,
|
||
Cipolletta E,
|
||
Doherty M,
|
||
Pascual E,
|
||
Perez-Ruiz F,
|
||
So A,
|
||
Jansen TL,
|
||
Kohler MJ,
|
||
Stamp LK,
|
||
Yinh J,
|
||
Adinolfi A,
|
||
Arad U,
|
||
Aung T,
|
||
Benillouche E,
|
||
Bortoluzzi A,
|
||
Dau J,
|
||
Maningding E,
|
||
Fang MA,
|
||
Figus FA,
|
||
Filippucci E,
|
||
Haslett J,
|
||
Janssen M,
|
||
Kaldas M,
|
||
Kimoto M,
|
||
Leamy K,
|
||
Navarro GM,
|
||
Sarzi-Puttini P,
|
||
Scirè C,
|
||
Silvagni E,
|
||
Sirotti S,
|
||
Stack JR,
|
||
Truong L,
|
||
Xie C,
|
||
Yokose C,
|
||
Hendry AM,
|
||
Terkeltaub R,
|
||
Taylor WJ,
|
||
Choi HK</span><br />
|
||
<span class="medgenPMjournal">Ann Rheum Dis</span>
|
||
2023 Oct;82(10):1248-1257.
|
||
Epub 2023 Jul 26
|
||
doi: 10.1136/ard-2023-224575.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37495237" target="_blank">37495237</a><a href="/pmc/articles/PMC10529191" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37494275">The 2023 ACR/EULAR Classification Criteria for Calcium Pyrophosphate Deposition Disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Abhishek A,
|
||
Tedeschi SK,
|
||
Pascart T,
|
||
Latourte A,
|
||
Dalbeth N,
|
||
Neogi T,
|
||
Fuller A,
|
||
Rosenthal A,
|
||
Becce F,
|
||
Bardin T,
|
||
Ea HK,
|
||
Filippou G,
|
||
FitzGerald J,
|
||
Iagnocco A,
|
||
Lioté F,
|
||
McCarthy GM,
|
||
Ramonda R,
|
||
Richette P,
|
||
Sivera F,
|
||
Andres M,
|
||
Cipolletta E,
|
||
Doherty M,
|
||
Pascual E,
|
||
Perez-Ruiz F,
|
||
So A,
|
||
Jansen TL,
|
||
Kohler MJ,
|
||
Stamp LK,
|
||
Yinh J,
|
||
Adinolfi A,
|
||
Arad U,
|
||
Aung T,
|
||
Benillouche E,
|
||
Bortoluzzi A,
|
||
Dau J,
|
||
Maningding E,
|
||
Fang MA,
|
||
Figus FA,
|
||
Filippucci E,
|
||
Haslett J,
|
||
Janssen M,
|
||
Kaldas M,
|
||
Kimoto M,
|
||
Leamy K,
|
||
Navarro GM,
|
||
Sarzi-Puttini P,
|
||
Scirè C,
|
||
Silvagni E,
|
||
Sirotti S,
|
||
Stack JR,
|
||
Truong L,
|
||
Xie C,
|
||
Yokose C,
|
||
Hendry AM,
|
||
Terkeltaub R,
|
||
Taylor WJ,
|
||
Choi HK</span><br />
|
||
<span class="medgenPMjournal">Arthritis Rheumatol</span>
|
||
2023 Oct;75(10):1703-1713.
|
||
Epub 2023 Jul 26
|
||
doi: 10.1002/art.42619.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37494275" target="_blank">37494275</a><a href="/pmc/articles/PMC10543651" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33012644">Imaging of crystalline arthropathy in 2020.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Filippucci E,
|
||
Reginato AM,
|
||
Thiele RG</span><br />
|
||
<span class="medgenPMjournal">Best Pract Res Clin Rheumatol</span>
|
||
2020 Dec;34(6):101595.
|
||
Epub 2020 Oct 1
|
||
doi: 10.1016/j.berh.2020.101595.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33012644" target="_blank">33012644</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24703345">Imaging in the crystal arthropathies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">McQueen FM,
|
||
Doyle A,
|
||
Dalbeth N</span><br />
|
||
<span class="medgenPMjournal">Rheum Dis Clin North Am</span>
|
||
2014 May;40(2):231-49.
|
||
Epub 2014 Feb 20
|
||
doi: 10.1016/j.rdc.2014.01.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24703345" target="_blank">24703345</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Chondrocalcinosis%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (295)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/38702175">Systematic literature review to inform the EULAR recommendations for the use of imaging in crystal-induced arthropathies in clinical practice.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gessl I,
|
||
Sakellariou G,
|
||
Wildner B,
|
||
Filippou G,
|
||
Mandl P,
|
||
D'Agostino MA,
|
||
Navarro-Compán V</span><br />
|
||
<span class="medgenPMjournal">Ann Rheum Dis</span>
|
||
2024 Aug 27;83(9):1208-1224.
|
||
doi: 10.1136/ard-2023-225247.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38702175" target="_blank">38702175</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36224305">Efficacy and safety of colchicine for the treatment of osteoarthritis: a systematic review and meta-analysis of intervention trials.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Singh A,
|
||
Molina-Garcia P,
|
||
Hussain S,
|
||
Paul A,
|
||
Das SK,
|
||
Leung YY,
|
||
Hill CL,
|
||
Danda D,
|
||
Samuels J,
|
||
Antony B</span><br />
|
||
<span class="medgenPMjournal">Clin Rheumatol</span>
|
||
2023 Mar;42(3):889-902.
|
||
Epub 2022 Oct 12
|
||
doi: 10.1007/s10067-022-06402-w.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36224305" target="_blank">36224305</a><a href="/pmc/articles/PMC9935673" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33677614">Chondrocalcinosis does not affect functional outcome and prosthesis survival in patients after total or unicompartmental knee arthroplasty: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Moret CS,
|
||
Iordache E,
|
||
D'Ambrosi R,
|
||
Hirschmann MT</span><br />
|
||
<span class="medgenPMjournal">Knee Surg Sports Traumatol Arthrosc</span>
|
||
2022 Mar;30(3):1039-1049.
|
||
Epub 2021 Mar 6
|
||
doi: 10.1007/s00167-021-06519-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33677614" target="_blank">33677614</a><a href="/pmc/articles/PMC8901495" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32359034">Biologics in the treatment of calcium pyrophosphate deposition disease: a systematic literature review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cipolletta E,
|
||
Di Matteo A,
|
||
Scanu A,
|
||
Isidori M,
|
||
Di Battista J,
|
||
Punzi L,
|
||
Grassi W,
|
||
Filippucci E</span><br />
|
||
<span class="medgenPMjournal">Clin Exp Rheumatol</span>
|
||
2020 Sep-Oct;38(5):1001-1007.
|
||
Epub 2020 Apr 28
|
||
<span class="bold">PMID: </span><a href="/pubmed/32359034" target="_blank">32359034</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31058426">Association between chondrocalcinosis and osteoarthritis: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wang Y,
|
||
Wei J,
|
||
Zeng C,
|
||
Xie D,
|
||
Li H,
|
||
Yang T,
|
||
Ding X,
|
||
Cui Y,
|
||
Xiong Y,
|
||
Li J,
|
||
Lei G</span><br />
|
||
<span class="medgenPMjournal">Int J Rheum Dis</span>
|
||
2019 Jul;22(7):1175-1182.
|
||
Epub 2019 May 6
|
||
doi: 10.1111/1756-185X.13583.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31058426" target="_blank">31058426</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Chondrocalcinosis%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (11)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
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|
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|
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|
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|
||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
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|
||
|
||
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<div class="portlet mgSection" id="ID_113">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0553730%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (7)</a></li>
|
||
<li><a href="/gtr/tests?term=C0553730%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (7)</a></li>
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