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||
<!--
|
||
UID=148270
|
||
ConceptID=C0751273
|
||
-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Infantile Krabbe disease</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>148270</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0751273</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Classic Globoid Cell Leukodystrophy; Early Onset Globoid Cell Leukodystrophy; Early-Onset Globoid Cell Leukodystrophy; Infantile Globoid Cell Leukodystrophy; Leukodystrophy, Globoid Cell, Classic; Leukodystrophy, Globoid Cell, Early-Onset; Leukodystrophy, Globoid Cell, Infantile</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Globoid cell leukodystrophy, early onset (189979005); Galactosylceramide lipidosis (189979005); Familial infantile diffuse brain sclerosis (189979005); Galactocerebroside beta-galactosidase deficiency - early onset (238030005); Infantile Krabbe disease (238030005)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>Monarch Initiative:</td>
|
||
<td><a href="https://monarchinitiative.org/disease/MONDO:0016089" target="_blank">MONDO:0016089</a></td></tr>
|
||
<tr><td>Orphanet:</td>
|
||
<td><a target="_blank" title="Orphanet: The portal for rare diseases and orphan drugs" href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=206436">ORPHA206436</a></td></tr></tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li><li><a href="#tabORDO">Orphanet</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet Ccolor round" title="Clinical test"><a target="_blank" href="/gtr/tests/?term=C0751273[DISCUI]&test_type=Clinical" ref="ncbi_uid=148270">C</a></span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Infantile Krabbe disease</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/14319" ref="tree=MeSH" title="MedGen record for Congenital, Hereditary, and Neonatal Diseases and Abnormalities">Congenital, Hereditary, and Neonatal Diseases and Abnormalities</a></span><ul><li><span class="TLline"><a href="/medgen/181981" ref="tree=MeSH" title="MedGen record for Inborn genetic diseases">Inborn genetic diseases</a></span><ul><li><span class="TLline"><a href="/medgen/6323" ref="tree=MeSH" title="MedGen record for Inborn errors of metabolism">Inborn errors of metabolism</a></span><ul><li><span class="TLline"><a href="/medgen/156005" ref="tree=MeSH" title="MedGen record for Brain Diseases, Metabolic, Inborn">Brain Diseases, Metabolic, Inborn</a></span><ul><li><span class="TLline"><a href="/medgen/148407" ref="tree=MeSH" title="MedGen record for Hereditary Central Nervous System Demyelinating Diseases">Hereditary Central Nervous System Demyelinating Diseases</a></span><ul><li><span class="TLline"><a href="/medgen/44131" ref="tree=MeSH" title="MedGen record for Galactosylceramide beta-galactosidase deficiency">Galactosylceramide beta-galactosidase deficiency</a></span><ul><li><span class="matched_ds">Infantile Krabbe disease</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div><div id="tabORDO">Follow <a target="_blank" href="http://www.orpha.net/consor/cgi-bin/Disease_Classif.php?lng=EN&data_id=156&PatId=18495&search=Disease_Classif_Simple&new=1" class="ital bold">this link</a> to review classifications for <span class="ital">Infantile Krabbe disease</span> in Orphanet.</div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/31090922">Ethical issues with testing and treatment for Krabbe disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ehmann P,
|
||
Lantos JD</span><br />
|
||
<span class="medgenPMjournal">Dev Med Child Neurol</span>
|
||
2019 Dec;61(12):1358-1361.
|
||
Epub 2019 May 15
|
||
doi: 10.1111/dmcn.14258.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31090922" target="_blank">31090922</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29391017">Consensus guidelines for newborn screening, diagnosis and treatment of infantile Krabbe disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kwon JM,
|
||
Matern D,
|
||
Kurtzberg J,
|
||
Wrabetz L,
|
||
Gelb MH,
|
||
Wenger DA,
|
||
Ficicioglu C,
|
||
Waldman AT,
|
||
Burton BK,
|
||
Hopkins PV,
|
||
Orsini JJ</span><br />
|
||
<span class="medgenPMjournal">Orphanet J Rare Dis</span>
|
||
2018 Feb 1;13(1):30.
|
||
doi: 10.1186/s13023-018-0766-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29391017" target="_blank">29391017</a><a href="/pmc/articles/PMC5796396" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27491217">Insights into the Pathogenesis and Treatment of Krabbe Disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bongarzone ER,
|
||
Escolar ML,
|
||
Gray SJ,
|
||
Kafri T,
|
||
Vite CH,
|
||
Sands MS</span><br />
|
||
<span class="medgenPMjournal">Pediatr Endocrinol Rev</span>
|
||
2016 Jun;13 Suppl 1:689-96.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27491217" target="_blank">27491217</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22infantile%20krabbe%20disease%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (10)</a></div><h3 class="subhead">Curated<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpCurated"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3><h3 class="nl vspace"><a href="https://www.acmg.net/PDFLibrary/Krabbe-Infantile.pdf" target="_blank">American College of Medical Genetics and Genomics, Newborn Screening ACT Sheet, Decreased galactocerebrosidase, elevated psychosine, Krabbe Disease (infantile form), 2022</a></h3>
|
||
<h3 class="nl vspace"><a href="https://www.acmg.net/PDFLibrary/Krabbe-Algorithm.pdf" target="_blank">American College of Medical Genetics and Genomics, Algorithm, Krabbe disease: galactocerebrosidase deficiency, 2022</a></h3>
|
||
</div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39499628">Infantile Krabbe disease (0-12 months), progression, and recommended endpoints for clinical trials.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Greco MR,
|
||
Lopez MA,
|
||
Beltran-Quintero ML,
|
||
Tuc Bengur E,
|
||
Poe MD,
|
||
Escolar ML</span><br />
|
||
<span class="medgenPMjournal">Ann Clin Transl Neurol</span>
|
||
2024 Dec;11(12):3064-3080.
|
||
Epub 2024 Nov 5
|
||
doi: 10.1002/acn3.52114.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39499628" target="_blank">39499628</a><a href="/pmc/articles/PMC11651195" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/35042231">Benefits of newborn screening and hematopoietic cell transplant in infantile Krabbe disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Page KM,
|
||
Ream MA,
|
||
Rangarajan HG,
|
||
Galindo R,
|
||
Mian AY,
|
||
Ho ML,
|
||
Provenzale J,
|
||
Gustafson KE,
|
||
Rubin J,
|
||
Shenoy S,
|
||
Kurtzberg J</span><br />
|
||
<span class="medgenPMjournal">Blood Adv</span>
|
||
2022 May 10;6(9):2947-2956.
|
||
doi: 10.1182/bloodadvances.2021006094.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35042231" target="_blank">35042231</a><a href="/pmc/articles/PMC9092415" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33150395">Long-term neurodevelopmental outcomes of hematopoietic stem cell transplantation for late-infantile Krabbe disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yoon IC,
|
||
Bascou NA,
|
||
Poe MD,
|
||
Szabolcs P,
|
||
Escolar ML</span><br />
|
||
<span class="medgenPMjournal">Blood</span>
|
||
2021 Apr 1;137(13):1719-1730.
|
||
doi: 10.1182/blood.2020005477.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33150395" target="_blank">33150395</a><a href="/pmc/articles/PMC8020262" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31090922">Ethical issues with testing and treatment for Krabbe disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ehmann P,
|
||
Lantos JD</span><br />
|
||
<span class="medgenPMjournal">Dev Med Child Neurol</span>
|
||
2019 Dec;61(12):1358-1361.
|
||
Epub 2019 May 15
|
||
doi: 10.1111/dmcn.14258.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31090922" target="_blank">31090922</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29391017">Consensus guidelines for newborn screening, diagnosis and treatment of infantile Krabbe disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kwon JM,
|
||
Matern D,
|
||
Kurtzberg J,
|
||
Wrabetz L,
|
||
Gelb MH,
|
||
Wenger DA,
|
||
Ficicioglu C,
|
||
Waldman AT,
|
||
Burton BK,
|
||
Hopkins PV,
|
||
Orsini JJ</span><br />
|
||
<span class="medgenPMjournal">Orphanet J Rare Dis</span>
|
||
2018 Feb 1;13(1):30.
|
||
doi: 10.1186/s13023-018-0766-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29391017" target="_blank">29391017</a><a href="/pmc/articles/PMC5796396" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Infantile%20Krabbe%20disease%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (17)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/31090922">Ethical issues with testing and treatment for Krabbe disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ehmann P,
|
||
Lantos JD</span><br />
|
||
<span class="medgenPMjournal">Dev Med Child Neurol</span>
|
||
2019 Dec;61(12):1358-1361.
|
||
Epub 2019 May 15
|
||
doi: 10.1111/dmcn.14258.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31090922" target="_blank">31090922</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29391017">Consensus guidelines for newborn screening, diagnosis and treatment of infantile Krabbe disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kwon JM,
|
||
Matern D,
|
||
Kurtzberg J,
|
||
Wrabetz L,
|
||
Gelb MH,
|
||
Wenger DA,
|
||
Ficicioglu C,
|
||
Waldman AT,
|
||
Burton BK,
|
||
Hopkins PV,
|
||
Orsini JJ</span><br />
|
||
<span class="medgenPMjournal">Orphanet J Rare Dis</span>
|
||
2018 Feb 1;13(1):30.
|
||
doi: 10.1186/s13023-018-0766-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29391017" target="_blank">29391017</a><a href="/pmc/articles/PMC5796396" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22585439">Intracranial optic nerve enlargement in infantile Krabbe disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Shah S,
|
||
Freeman E,
|
||
Wolf V,
|
||
Murthy S,
|
||
Lotze T</span><br />
|
||
<span class="medgenPMjournal">Neurology</span>
|
||
2012 May 15;78(20):e126.
|
||
doi: 10.1212/WNL.0b013e3182563bad.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22585439" target="_blank">22585439</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/14623741">Infantile Krabbe disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Korn-Lubetzki I,
|
||
Nevo Y</span><br />
|
||
<span class="medgenPMjournal">Arch Neurol</span>
|
||
2003 Nov;60(11):1643-4.
|
||
doi: 10.1001/archneur.60.11.1643.
|
||
<span class="bold">PMID: </span><a href="/pubmed/14623741" target="_blank">14623741</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8237697">Infantile Krabbe disease: complementary CT and MR findings.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Choi S,
|
||
Enzmann DR</span><br />
|
||
<span class="medgenPMjournal">AJNR Am J Neuroradiol</span>
|
||
1993 Sep-Oct;14(5):1164-6.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8237697" target="_blank">8237697</a><a href="/pmc/articles/PMC8332761" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Infantile%20Krabbe%20disease%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (39)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39499628">Infantile Krabbe disease (0-12 months), progression, and recommended endpoints for clinical trials.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Greco MR,
|
||
Lopez MA,
|
||
Beltran-Quintero ML,
|
||
Tuc Bengur E,
|
||
Poe MD,
|
||
Escolar ML</span><br />
|
||
<span class="medgenPMjournal">Ann Clin Transl Neurol</span>
|
||
2024 Dec;11(12):3064-3080.
|
||
Epub 2024 Nov 5
|
||
doi: 10.1002/acn3.52114.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39499628" target="_blank">39499628</a><a href="/pmc/articles/PMC11651195" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27491217">Insights into the Pathogenesis and Treatment of Krabbe Disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bongarzone ER,
|
||
Escolar ML,
|
||
Gray SJ,
|
||
Kafri T,
|
||
Vite CH,
|
||
Sands MS</span><br />
|
||
<span class="medgenPMjournal">Pediatr Endocrinol Rev</span>
|
||
2016 Jun;13 Suppl 1:689-96.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27491217" target="_blank">27491217</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/27171547">Clinical outcomes of children with abnormal newborn screening results for Krabbe disease in New York State.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wasserstein MP,
|
||
Andriola M,
|
||
Arnold G,
|
||
Aron A,
|
||
Duffner P,
|
||
Erbe RW,
|
||
Escolar ML,
|
||
Estrella L,
|
||
Galvin-Parton P,
|
||
Iglesias A,
|
||
Kay DM,
|
||
Kronn DF,
|
||
Kurtzberg J,
|
||
Kwon JM,
|
||
Langan TJ,
|
||
Levy PA,
|
||
Naidich TP,
|
||
Orsini JJ,
|
||
Pellegrino JE,
|
||
Provenzale JM,
|
||
Wenger DA,
|
||
Caggana M</span><br />
|
||
<span class="medgenPMjournal">Genet Med</span>
|
||
2016 Dec;18(12):1235-1243.
|
||
Epub 2016 May 12
|
||
doi: 10.1038/gim.2016.35.
|
||
<span class="bold">PMID: </span><a href="/pubmed/27171547" target="_blank">27171547</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22964446">Prolonged survival and serial magnetic resonance imaging/magnetic resonance spectroscopy changes in infantile Krabbe disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Udow S,
|
||
Bunge M,
|
||
Ryner L,
|
||
Mhanni AA,
|
||
Salman MS</span><br />
|
||
<span class="medgenPMjournal">Pediatr Neurol</span>
|
||
2012 Oct;47(4):299-302.
|
||
doi: 10.1016/j.pediatrneurol.2012.06.015.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22964446" target="_blank">22964446</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/18265968">Thickening and enhancement of multiple cranial nerves in conjunction with cystic white matter lesions in early infantile Krabbe disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Beslow LA,
|
||
Schwartz ES,
|
||
Bönnemann CG</span><br />
|
||
<span class="medgenPMjournal">Pediatr Radiol</span>
|
||
2008 Jun;38(6):694-6.
|
||
Epub 2008 Feb 12
|
||
doi: 10.1007/s00247-008-0763-7.
|
||
<span class="bold">PMID: </span><a href="/pubmed/18265968" target="_blank">18265968</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Infantile%20Krabbe%20disease%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (5)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/29120458">Precision newborn screening for lysosomal disorders.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Minter Baerg MM,
|
||
Stoway SD,
|
||
Hart J,
|
||
Mott L,
|
||
Peck DS,
|
||
Nett SL,
|
||
Eckerman JS,
|
||
Lacey JM,
|
||
Turgeon CT,
|
||
Gavrilov D,
|
||
Oglesbee D,
|
||
Raymond K,
|
||
Tortorelli S,
|
||
Matern D,
|
||
Mørkrid L,
|
||
Rinaldo P</span><br />
|
||
<span class="medgenPMjournal">Genet Med</span>
|
||
2018 Aug;20(8):847-854.
|
||
Epub 2017 Nov 9
|
||
doi: 10.1038/gim.2017.194.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29120458" target="_blank">29120458</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25844309">Regional differences in fiber tractography predict neurodevelopmental outcomes in neonates with infantile Krabbe disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gupta A,
|
||
Poe MD,
|
||
Styner MA,
|
||
Panigrahy A,
|
||
Escolar ML</span><br />
|
||
<span class="medgenPMjournal">Neuroimage Clin</span>
|
||
2015;7:792-8.
|
||
Epub 2014 Sep 26
|
||
doi: 10.1016/j.nicl.2014.09.014.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25844309" target="_blank">25844309</a><a href="/pmc/articles/PMC4375637" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21824559">Early infantile Krabbe disease: results of the World-Wide Krabbe Registry.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Duffner PK,
|
||
Barczykowski A,
|
||
Jalal K,
|
||
Yan L,
|
||
Kay DM,
|
||
Carter RL</span><br />
|
||
<span class="medgenPMjournal">Pediatr Neurol</span>
|
||
2011 Sep;45(3):141-8.
|
||
doi: 10.1016/j.pediatrneurol.2011.05.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21824559" target="_blank">21824559</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/20601893">Weighing the evidence for newborn screening for early-infantile Krabbe disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kemper AR,
|
||
Knapp AA,
|
||
Green NS,
|
||
Comeau AM,
|
||
Metterville DR,
|
||
Perrin JM</span><br />
|
||
<span class="medgenPMjournal">Genet Med</span>
|
||
2010 Sep;12(9):539-43.
|
||
doi: 10.1097/GIM.0b013e3181e85721.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20601893" target="_blank">20601893</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16923928">A staging system for infantile Krabbe disease to predict outcome after unrelated umbilical cord blood transplantation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Escolar ML,
|
||
Poe MD,
|
||
Martin HR,
|
||
Kurtzberg J</span><br />
|
||
<span class="medgenPMjournal">Pediatrics</span>
|
||
2006 Sep;118(3):e879-89.
|
||
Epub 2006 Aug 21
|
||
doi: 10.1542/peds.2006-0747.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16923928" target="_blank">16923928</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Infantile%20Krabbe%20disease%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (12)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/29933067">Long-Term Functional Outcomes after Hematopoietic Stem Cell Transplant for Early Infantile Krabbe Disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Allewelt H,
|
||
Taskindoust M,
|
||
Troy J,
|
||
Page K,
|
||
Wood S,
|
||
Parikh S,
|
||
Prasad VK,
|
||
Kurtzberg J</span><br />
|
||
<span class="medgenPMjournal">Biol Blood Marrow Transplant</span>
|
||
2018 Nov;24(11):2233-2238.
|
||
Epub 2018 Jun 20
|
||
doi: 10.1016/j.bbmt.2018.06.020.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29933067" target="_blank">29933067</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29120458">Precision newborn screening for lysosomal disorders.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Minter Baerg MM,
|
||
Stoway SD,
|
||
Hart J,
|
||
Mott L,
|
||
Peck DS,
|
||
Nett SL,
|
||
Eckerman JS,
|
||
Lacey JM,
|
||
Turgeon CT,
|
||
Gavrilov D,
|
||
Oglesbee D,
|
||
Raymond K,
|
||
Tortorelli S,
|
||
Matern D,
|
||
Mørkrid L,
|
||
Rinaldo P</span><br />
|
||
<span class="medgenPMjournal">Genet Med</span>
|
||
2018 Aug;20(8):847-854.
|
||
Epub 2017 Nov 9
|
||
doi: 10.1038/gim.2017.194.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29120458" target="_blank">29120458</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/25844309">Regional differences in fiber tractography predict neurodevelopmental outcomes in neonates with infantile Krabbe disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Gupta A,
|
||
Poe MD,
|
||
Styner MA,
|
||
Panigrahy A,
|
||
Escolar ML</span><br />
|
||
<span class="medgenPMjournal">Neuroimage Clin</span>
|
||
2015;7:792-8.
|
||
Epub 2014 Sep 26
|
||
doi: 10.1016/j.nicl.2014.09.014.
|
||
<span class="bold">PMID: </span><a href="/pubmed/25844309" target="_blank">25844309</a><a href="/pmc/articles/PMC4375637" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/21824559">Early infantile Krabbe disease: results of the World-Wide Krabbe Registry.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Duffner PK,
|
||
Barczykowski A,
|
||
Jalal K,
|
||
Yan L,
|
||
Kay DM,
|
||
Carter RL</span><br />
|
||
<span class="medgenPMjournal">Pediatr Neurol</span>
|
||
2011 Sep;45(3):141-8.
|
||
doi: 10.1016/j.pediatrneurol.2011.05.007.
|
||
<span class="bold">PMID: </span><a href="/pubmed/21824559" target="_blank">21824559</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16923928">A staging system for infantile Krabbe disease to predict outcome after unrelated umbilical cord blood transplantation.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Escolar ML,
|
||
Poe MD,
|
||
Martin HR,
|
||
Kurtzberg J</span><br />
|
||
<span class="medgenPMjournal">Pediatrics</span>
|
||
2006 Sep;118(3):e879-89.
|
||
Epub 2006 Aug 21
|
||
doi: 10.1542/peds.2006-0747.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16923928" target="_blank">16923928</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Infantile%20Krabbe%20disease%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (8)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/20601893">Weighing the evidence for newborn screening for early-infantile Krabbe disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kemper AR,
|
||
Knapp AA,
|
||
Green NS,
|
||
Comeau AM,
|
||
Metterville DR,
|
||
Perrin JM</span><br />
|
||
<span class="medgenPMjournal">Genet Med</span>
|
||
2010 Sep;12(9):539-43.
|
||
doi: 10.1097/GIM.0b013e3181e85721.
|
||
<span class="bold">PMID: </span><a href="/pubmed/20601893" target="_blank">20601893</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Infantile%20Krabbe%20disease%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1)</a></div></div>
|
||
</div>
|
||
</div></div></div></div></div></div></div>
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last">
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div>
|
||
|
||
<!-- MedGen supplemental column starts here -->
|
||
<div class="rightCol mgCol">
|
||
<div class="portlet mgSection" id="ID_113">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul id="my-toc"></ul></div>
|
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|
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|
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<div class="portlet mgSection" id="ID_106">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Genetic_Testing_Registry">Genetic Testing Registry</h1><a sid="106" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul><li><a href="/gtr/tests?term=C0751273%5bDISCUI%5d&filter=method%3A1%5F1" target="_blank">Analyte (3)</a></li>
|
||
<li><a href="/gtr/tests?term=C0751273%5bDISCUI%5d&filter=method%3A2%5F8" target="_blank">Deletion/duplication analysis (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C0751273%5bDISCUI%5d&filter=method%3A1%5F2" target="_blank">Enzyme assay (3)</a></li>
|
||
<li><a href="/gtr/tests?term=C0751273%5bDISCUI%5d&filter=method%3A2%5F7" target="_blank">Sequence analysis of the entire coding region (1)</a></li>
|
||
<li><a href="/gtr/tests?term=C0751273%5bDISCUI%5d&filter=method%3A2%5F19" target="_blank">Targeted variant analysis (2)</a></li>
|
||
<li class="portletSeeAll portletSeeAllPad"><total><a href="/gtr/tests?term=C0751273%5bDISCUI%5d" target="_blank">See all (9)</a></total></li>
|
||
</ul></div>
|
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|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Clinical_resources">Clinical resources</h1><a sid="119" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln"><ul><li><a href="http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Expert=206436" target="_blank">Orphanet</a></li><li><a href="https://clinicaltrials.gov/search?cond=Infantile%20Krabbe%20disease" target="_blank">ClinicalTrials.gov</a></li></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_121">
|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Practice_guidelines">Practice guidelines</h1><a sid="121" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22infantile%20krabbe%20disease%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li><li><a target="_blank" href="/books/?term=((%22clinical%20guidelines%22%5BResource%20Type%5D)%20OR%20%22practice%20guideline%22%5BPublication%20Type%5D)%20AND%20(%22Infantile%20Krabbe%20disease%22)">Bookshelf</a><div class="help-popup">See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul><h3 class="subhead">Curated</h3><ul class="a_poppers"><li><a target="_blank" href="https://www.acmg.net/PDFLibrary/Krabbe-Infantile.pdf">ACMG ACT, 2022</a><div>American College of Medical Genetics and Genomics, Newborn Screening ACT Sheet, Decreased galactocerebrosidase, elevated psychosine, Krabbe Disease (infantile form), 2022</div></li><li><a target="_blank" href="https://www.acmg.net/PDFLibrary/Krabbe-Algorithm.pdf">ACMG Algorithm, 2022</a><div>American College of Medical Genetics and Genomics, Algorithm, Krabbe disease: galactocerebrosidase deficiency, 2022</div></li></ul></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_116">
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<div class="portlet_content ln"><ul><li><a href="https://vsearch.nlm.nih.gov/vivisimo/cgi-bin/query-meta?v:project=medlineplus&query=Infantile%20Krabbe%20disease" target="_blank">MedlinePlus</a></li><li><a href="https://rarediseases.info.nih.gov/diseases/20343/disease" target="_blank">NCATS Office of Rare Diseases Research (GARD)</a></li></ul></div>
|
||
</div>
|
||
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|
||
<div class="portlet brieflink">
|
||
<div class="portlet_head">
|
||
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|
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<h3>Reviews</h3>
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<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenReviews.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Reviews" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.MedGen_SingleItemSuplCluster.MedGenReviews.Shutter"></a>
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||
<div class="portlet_content">
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<ul>
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<li>
|
||
<a href="/pubmed/clinical?term=Infantile%20Krabbe%20disease" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=1&linkpostotal=2" target="_blank">PubMed Clinical Queries</a>
|
||
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|
||
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|
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<a href="/pubmed?term=Infantile%20Krabbe%20disease%20AND%20humans[mesh]%20AND%20review[publication%20type]" ref="ncbi_uid=&discoId=gtr_reviews&linkpos=2&linkpostotal=2" target="_blank">Reviews in PubMed</a>
|
||
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|
||
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|
||
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|
||
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|
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|
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<!-- MedGen supplemental column ends here -->
|
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<div class="portlet brieflink">
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||
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|
||
<h3>Related information</h3>
|
||
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|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests?term=C0751273[DISCUI]" ref="log$=recordlinks">GTR</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related information in GTR</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
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<a class="brieflinkpopperctrl" href="/gtr/tests?term=C0751273[DISCUI]&test_type=Clinical" ref="log$=recordlinks">GTR(Clinical)</a>
|
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<div class="brieflinkpop offscreen_noflow">Clinical tests in GTR</div>
|
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<a class="brieflinkpopperctrl" href="/mesh?LinkName=medgen_mesh&from_uid=148270" ref="log$=recordlinks">MeSH</a>
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<div class="brieflinkpop offscreen_noflow">Related Medical Subject Headings</div>
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<a class="brieflinkpopperctrl" href="/pubmed?LinkName=medgen_pubmed&from_uid=148270" ref="log$=recordlinks">PubMed</a>
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<div class="brieflinkpop offscreen_noflow">Related literature resources in PubMed</div>
|
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|
||
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|
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|
||
|
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<a name="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory" sid="1" realname="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory" cmd="ClearHT" href="?cmd=ClearHT&" onclick="return false;" id="EntrezSystem2.PEntrez.MedGen.MedGen_ResultsPanel.HistoryDisplay.ClearHistory">
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Turn On
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|
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|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67d4897984f3725e59022177">Infantile Krabbe disease</a>
|
||
<div class="ralinkpop offscreen_noflow">Infantile Krabbe disease<div class="brieflinkpopdesc"></div></div>
|
||
<div class="tertiary">MedGen</div>
|
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</li>
|
||
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|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=2" href="/portal/utils/pageresolver.fcgi?recordid=67d489772f30673f7bc14ada">Adult Krabbe disease</a>
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