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<meta name="keywords" content="C4477024, finding, increased circulating nt-probnp concentration, increased nt-probnp level, autosomal dominant, autosomal recessive, birth defects, chromosomal disease, chromosome, clinical features, clinical findings, clinical genetics, clinical recommendations, clinvar, congenital chromosomal disease, consumer genetic resources, cytogenetic location, disease characteristics, disease definitions, disease descriptions, disease ontology, disease synonyms, disease vocabulary, dysmorphology, entrez, familial disease, gene, gene-disease relationship, genereviews, genetic disease, genetic disorder, genetic terminology, genetic testing registry, genetics home reference, genomic disease, gtr, hereditary disease, heritable disease, hpo, human phenotype ontology, inherited disease, management guidelines, maternal inheritance, medgen, medical genetics, medical subject headings, mesh, mitochondrial inheritance, mode of inheritance, national center for biotechnology information, national institutes of health, national library of medicine, ncbi, nih, nlm, omim, ordo, orphanet, paternal inheritance, phenome, position statements, professional practice guidelines, rare disease, reference sequence, refseq, snomed ct, syndrome, undiagnosed diseases, x-linked recessive" /><meta name="description" content="An elevated level of circulating N-terminal part of the prohormone of B-type natriuretic peptide (BNP)." /><meta name="robots" content="index,nofollow,noarchive" />
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<!--
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UID=1385064
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ConceptID=C4477024
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Increased circulating NT-proBNP concentration</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1385064</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4477024</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
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<td>Increased NT-proBNP level</td></tr>
|
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<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0031185">HP:0031185</a></td></tr>
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</tbody></table></div><div class="rprt-body jig-ncbiinpagenav" data-jigconfig="smoothScroll: false, gotoTopLink: true, gotoTopLinkText: '', gotoTopLinkAttrs: {'title': 'Go to the top of the page'},allHeadingLevels: ['h1'], topOfPageTOC: true, tocId: 'my-toc'"><div id="rprt-tabs-1" class="rprt-tab"><div id="tb-termsProp-1"><div class="leftCol mgCol"><div>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln">An elevated level of circulating N-terminal part of the prohormone of B-type natriuretic peptide (BNP). [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Increased circulating NT-proBNP concentration</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/867443" ref="tree=MeSH" title="MedGen record for Phenotypic abnormality">Phenotypic abnormality</a></span><ul><li><span class="TLline"><a href="/medgen/867398" ref="tree=MeSH" title="MedGen record for Abnormality of metabolism/homeostasis">Abnormality of metabolism/homeostasis</a></span><ul><li><span class="TLline"><a href="/medgen/1701080" ref="tree=MeSH" title="MedGen record for Abnormal circulating metabolite concentration">Abnormal circulating metabolite concentration</a></span><ul><li><span class="TLline"><a href="/medgen/892289" ref="tree=MeSH" title="MedGen record for Abnormal circulating protein concentration">Abnormal circulating protein concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1863990" ref="tree=MeSH" title="MedGen record for Abnormal circulating atrial natriuretic peptide pro-hormone concentration">Abnormal circulating atrial natriuretic peptide pro-hormone concentration</a></span><ul><li><span class="TLline"><a href="/medgen/1389340" ref="tree=MeSH" title="MedGen record for Abnormal circulating B-type natriuretic peptide concentration">Abnormal circulating B-type natriuretic peptide concentration</a></span><ul><li><span class="matched_ds">Increased circulating NT-proBNP concentration</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
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</div>
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<div class="portlet mgSection" id="ID_112">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln clinfeat">
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<div class="divPopper rprt" id="rdis_5340"><div><strong>Glycogen storage disease, type II</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>5340</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0017921</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Pompe disease is classified by age of onset, organ involvement, severity, and rate of progression. Infantile-onset Pompe disease (IOPD; individuals with onset before age 12 months with cardiomyopathy) may be apparent in utero but more typically onset is at the median age of four months with hypotonia, generalized muscle weakness, feeding difficulties, failure to thrive, respiratory distress, and hypertrophic cardiomyopathy. Without treatment by enzyme replacement therapy (ERT), IOPD commonly results in death by age two years from progressive left ventricular outflow obstruction and respiratory insufficiency. Late-onset Pompe disease (LOPD; including: (a) individuals with onset before age 12 months without cardiomyopathy; and (b) all individuals with onset after age 12 months) is characterized by proximal muscle weakness and respiratory insufficiency; clinically significant cardiac involvement is uncommon.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/5340">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_354526"><div><strong>Familial partial lipodystrophy, Dunnigan type</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>354526</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1720860</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Familial partial lipodystrophy (FPLD) is a metabolic disorder characterized by abnormal subcutaneous adipose tissue distribution beginning in late childhood or early adult life. Affected individuals gradually lose fat from the upper and lower extremities and the gluteal and truncal regions, resulting in a muscular appearance with prominent superficial veins. In some patients, adipose tissue accumulates on the face and neck, causing a double chin, fat neck, or cushingoid appearance. Metabolic abnormalities include insulin-resistant diabetes mellitus with acanthosis nigricans and hypertriglyceridemia; hirsutism and menstrual abnormalities occur infrequently. Familial partial lipodystrophy may also be referred to as lipoatrophic diabetes mellitus, but the essential feature is loss of subcutaneous fat (review by Garg, 2004). The disorder may be misdiagnosed as Cushing disease (see 219080) (Kobberling and Dunnigan, 1986; Garg, 2004). Genetic Heterogeneity of Familial Partial Lipodystrophy Familial partial lipodystrophy is a clinically and genetically heterogeneous disorder. Types 1 and 2 were originally described as clinical subtypes: type 1 (FPLD1; 608600), characterized by loss of subcutaneous fat confined to the limbs (Kobberling et al., 1975), and FPLD2, characterized by loss of subcutaneous fat from the limbs and trunk (Dunnigan et al., 1974; Kobberling and Dunnigan, 1986). No genetic basis for FPLD1 has yet been delineated. FPLD3 (604367) is caused by mutation in the PPARG gene (601487) on chromosome 3p25; FPLD4 (613877) is caused by mutation in the PLIN1 gene (170290) on chromosome 15q26; FPLD5 (615238) is caused by mutation in the CIDEC gene (612120) on chromosome 3p25; FPLD6 (615980) is caused by mutation in the LIPE gene (151750) on chromosome 19q13; FPLD7 (606721) is caused by mutation in the CAV1 gene (601047) on chromosome 7q31; FPLD8 (620679), caused by mutation in the ADRA2A gene (104210) on chromosome 10q25; and FPLD9 (620683), caused by mutation in the PLAAT3 gene (613867) on chromosome 11q12.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/354526">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1841010"><div><strong>Mitochondrial trifunctional protein deficiency 2</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1841010</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5830374</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Long-chain hydroxyacyl-CoA dehydrogenase (LCHAD) deficiency and trifunctional protein (TFP) deficiency are caused by impairment of mitochondrial TFP. TFP has three enzymatic activities – long-chain enoyl-CoA hydratase, long-chain 3-hydroxyacyl-CoA dehydrogenase, and long-chain 3-ketoacyl-CoA thiolase. In individuals with LCHAD deficiency, there is isolated deficiency of long-chain 3-hydroxyacyl-CoA dehydrogenase, while deficiency of all three enzymes occurs in individuals with TFP deficiency. Individuals with TFP deficiency can present with a severe-to-mild phenotype, while individuals with LCHAD deficiency typically present with a severe-to-intermediate phenotype. Neonates with the severe phenotype present within a few days of birth with hypoglycemia, hepatomegaly, encephalopathy, and often cardiomyopathy. The intermediate phenotype is characterized by hypoketotic hypoglycemia precipitated by infection or fasting in infancy. The mild (late-onset) phenotype is characterized by myopathy and/or neuropathy. Long-term complications include peripheral neuropathy and retinopathy.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1841010">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1863339"><div><strong>Pulmonary hypertension, primary, 6</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1863339</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5935600</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Primary pulmonary hypertension-6 (PPH6) is characterized by markedly elevated pulmonary arterial hypertension, associated with reduced oxygen saturation and diffuse ground-glass opacities on chest x-ray. Lung biopsy shows thickening of the alveolar septae and abnormally proliferating capillaries (Postma et al., 2023). For a general phenotypic description and a discussion of genetic heterogeneity of primary pulmonary hypertension, see PPH1 (178600).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1863339">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1857440"><div><strong>Proteasome-associated autoinflammatory syndrome 6</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1857440</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5935614</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Proteasome-associated autoinflammatory syndrome-6 (PRAAS6) is characterized by a proteasome-associated autoinflammatory syndrome with immunodeficiency (Kanazawa et al., 2021).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1857440">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1861075"><div><strong>Cardiomyopathy, dilated, 2K</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1861075</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5935636</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Dilated cardiomyopathy-2K (CMD2K) is a severe form of autosomal recessive CMD, characterized by predominantly left ventricular involvement, although patients with biventricular disease have been observed. Affected individuals show localized subepicardial and midmyocardial fibrosis, fibrofatty infiltration of the septum and posterior wall, and/or diffuse myocardial fibrosis. Patients experience atrial and ventricular arrhythmias, including atrial tachycardia, flutter, and fibrillation; ventricular and supraventricular extrasystoles; and nonsustained as well as sustained ventricular tachycardia. Severe systolic dysfunction results in heart failure; sudden death may occur, and some patients require cardiac transplantation (Helio et al., 2021; Maver et al., 2022; Ochoa et al., 2024). For a general phenotypic description and discussion of genetic heterogeneity of dilated cardiomyopathy, see CMD1A (115200).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1861075">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1861075" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Cardiomyopathy, dilated, 2K</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_354526" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Familial partial lipodystrophy, Dunnigan type</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_5340" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Glycogen storage disease, type II</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1841010" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Mitochondrial trifunctional protein deficiency 2</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1857440" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Proteasome-associated autoinflammatory syndrome 6</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1863339" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Pulmonary hypertension, primary, 6</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/36966429">Fetal NT-proBNP levels and their course in severe anemia during intrauterine treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Siebers P,
|
||
Gembruch U,
|
||
Merz WM,
|
||
Recker F,
|
||
Müller A,
|
||
Strizek B,
|
||
Geipel A,
|
||
Berg C,
|
||
Weber EC</span><br />
|
||
<span class="medgenPMjournal">Arch Gynecol Obstet</span>
|
||
2024 Apr;309(4):1341-1351.
|
||
Epub 2023 Mar 26
|
||
doi: 10.1007/s00404-023-07006-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36966429" target="_blank">36966429</a><a href="/pmc/articles/PMC10894143" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22546865">Circulating N-terminal pro-B-type natriuretic peptide in fetal anemia before and after treatment.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Merz WM,
|
||
Kübler K,
|
||
Fimmers R,
|
||
Stoffel-Wagner B,
|
||
Geipel A,
|
||
Gembruch U</span><br />
|
||
<span class="medgenPMjournal">Pediatr Res</span>
|
||
2012 Aug;72(2):174-8.
|
||
doi: 10.1038/pr.2012.53.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22546865" target="_blank">22546865</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22156668">Circulating troponin as measured by a sensitive assay for cardiovascular risk assessment in primary prevention.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Leistner DM,
|
||
Klotsche J,
|
||
Pieper L,
|
||
Stalla GK,
|
||
Lehnert H,
|
||
Silber S,
|
||
März W,
|
||
Wittchen HU,
|
||
Zeiher AM;
|
||
DETECT Study Group</span><br />
|
||
<span class="medgenPMjournal">Clin Chem</span>
|
||
2012 Jan;58(1):200-8.
|
||
Epub 2011 Dec 7
|
||
doi: 10.1373/clinchem.2011.174292.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22156668" target="_blank">22156668</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(increased%20circulating%20nt-probnp%20concentration)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (5)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39540306">A Proteomics-Based Approach for Prediction of Different Cardiovascular Diseases and Dementia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ho FK,
|
||
Mark PB,
|
||
Lees JS,
|
||
Pell JP,
|
||
Strawbridge RJ,
|
||
Kimenai DM,
|
||
Mills NL,
|
||
Woodward M,
|
||
McMurray JJV,
|
||
Sattar N,
|
||
Welsh P</span><br />
|
||
<span class="medgenPMjournal">Circulation</span>
|
||
2025 Feb 4;151(5):277-287.
|
||
Epub 2024 Nov 14
|
||
doi: 10.1161/CIRCULATIONAHA.124.070454.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39540306" target="_blank">39540306</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37603600">Cardiorenal Biomarkers, Canagliflozin, and Outcomes in Diabetic Kidney Disease: The CREDENCE Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Januzzi JL,
|
||
Mohebi R,
|
||
Liu Y,
|
||
Sattar N,
|
||
Heerspink HJL,
|
||
Tefera E,
|
||
Vaduganathan M,
|
||
Butler J,
|
||
Yavin Y,
|
||
Li J,
|
||
Pollock CA,
|
||
Perkovic V,
|
||
Neal B,
|
||
Hansen MK</span><br />
|
||
<span class="medgenPMjournal">Circulation</span>
|
||
2023 Aug 22;148(8):651-660.
|
||
Epub 2023 Aug 21
|
||
doi: 10.1161/CIRCULATIONAHA.123.065251.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37603600" target="_blank">37603600</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37184278">Increased circulating phenylacetylglutamine concentration elevates the predictive value of cardiovascular event risk in heart failure patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wei H,
|
||
Wu J,
|
||
Wang H,
|
||
Huang J,
|
||
Li C,
|
||
Zhang Y,
|
||
Song Y,
|
||
Zhou Z,
|
||
Sun Y,
|
||
Xiao L,
|
||
Peng L,
|
||
Chen C,
|
||
Zhao C,
|
||
Wang DW</span><br />
|
||
<span class="medgenPMjournal">J Intern Med</span>
|
||
2023 Oct;294(4):515-530.
|
||
Epub 2023 May 30
|
||
doi: 10.1111/joim.13653.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37184278" target="_blank">37184278</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36148485">Albuminuria as a marker of systemic congestion in patients with heart failure.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Boorsma EM,
|
||
Ter Maaten JM,
|
||
Damman K,
|
||
van Essen BJ,
|
||
Zannad F,
|
||
van Veldhuisen DJ,
|
||
Samani NJ,
|
||
Dickstein K,
|
||
Metra M,
|
||
Filippatos G,
|
||
Lang CC,
|
||
Ng L,
|
||
Anker SD,
|
||
Cleland JG,
|
||
Pellicori P,
|
||
Gansevoort RT,
|
||
Heerspink HJL,
|
||
Voors AA,
|
||
Emmens JE</span><br />
|
||
<span class="medgenPMjournal">Eur Heart J</span>
|
||
2023 Feb 1;44(5):368-380.
|
||
doi: 10.1093/eurheartj/ehac528.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36148485" target="_blank">36148485</a><a href="/pmc/articles/PMC9890244" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30846338">B-Type Natriuretic Peptide During Treatment With Sacubitril/Valsartan: The PARADIGM-HF Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Myhre PL,
|
||
Vaduganathan M,
|
||
Claggett B,
|
||
Packer M,
|
||
Desai AS,
|
||
Rouleau JL,
|
||
Zile MR,
|
||
Swedberg K,
|
||
Lefkowitz M,
|
||
Shi V,
|
||
McMurray JJV,
|
||
Solomon SD</span><br />
|
||
<span class="medgenPMjournal">J Am Coll Cardiol</span>
|
||
2019 Mar 26;73(11):1264-1272.
|
||
Epub 2019 Mar 4
|
||
doi: 10.1016/j.jacc.2019.01.018.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30846338" target="_blank">30846338</a><a href="/pmc/articles/PMC7955687" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Increased%20circulating%20NT-proBNP%20concentration%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (141)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39540306">A Proteomics-Based Approach for Prediction of Different Cardiovascular Diseases and Dementia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ho FK,
|
||
Mark PB,
|
||
Lees JS,
|
||
Pell JP,
|
||
Strawbridge RJ,
|
||
Kimenai DM,
|
||
Mills NL,
|
||
Woodward M,
|
||
McMurray JJV,
|
||
Sattar N,
|
||
Welsh P</span><br />
|
||
<span class="medgenPMjournal">Circulation</span>
|
||
2025 Feb 4;151(5):277-287.
|
||
Epub 2024 Nov 14
|
||
doi: 10.1161/CIRCULATIONAHA.124.070454.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39540306" target="_blank">39540306</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/38299345">Proteomic Associations of NT-proBNP (N-Terminal Pro-B-Type Natriuretic Peptide) in Heart Failure With Preserved Ejection Fraction.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Azzo JD,
|
||
Dib MJ,
|
||
Zagkos L,
|
||
Zhao L,
|
||
Wang Z,
|
||
Chang CP,
|
||
Ebert C,
|
||
Salman O,
|
||
Gan S,
|
||
Zamani P,
|
||
Cohen JB,
|
||
van Empel V,
|
||
Richards AM,
|
||
Javaheri A,
|
||
Mann DL,
|
||
Rietzschel ER,
|
||
Schafer PH,
|
||
Seiffert DA,
|
||
Gill D,
|
||
Burgess S,
|
||
Ramirez-Valle F,
|
||
Gordon DA,
|
||
Cappola TP,
|
||
Chirinos JA</span><br />
|
||
<span class="medgenPMjournal">Circ Heart Fail</span>
|
||
2024 Feb;17(2):e011146.
|
||
Epub 2024 Feb 1
|
||
doi: 10.1161/CIRCHEARTFAILURE.123.011146.
|
||
<span class="bold">PMID: </span><a href="/pubmed/38299345" target="_blank">38299345</a><a href="/pmc/articles/PMC7615693" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37603600">Cardiorenal Biomarkers, Canagliflozin, and Outcomes in Diabetic Kidney Disease: The CREDENCE Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Januzzi JL,
|
||
Mohebi R,
|
||
Liu Y,
|
||
Sattar N,
|
||
Heerspink HJL,
|
||
Tefera E,
|
||
Vaduganathan M,
|
||
Butler J,
|
||
Yavin Y,
|
||
Li J,
|
||
Pollock CA,
|
||
Perkovic V,
|
||
Neal B,
|
||
Hansen MK</span><br />
|
||
<span class="medgenPMjournal">Circulation</span>
|
||
2023 Aug 22;148(8):651-660.
|
||
Epub 2023 Aug 21
|
||
doi: 10.1161/CIRCULATIONAHA.123.065251.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37603600" target="_blank">37603600</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36148485">Albuminuria as a marker of systemic congestion in patients with heart failure.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Boorsma EM,
|
||
Ter Maaten JM,
|
||
Damman K,
|
||
van Essen BJ,
|
||
Zannad F,
|
||
van Veldhuisen DJ,
|
||
Samani NJ,
|
||
Dickstein K,
|
||
Metra M,
|
||
Filippatos G,
|
||
Lang CC,
|
||
Ng L,
|
||
Anker SD,
|
||
Cleland JG,
|
||
Pellicori P,
|
||
Gansevoort RT,
|
||
Heerspink HJL,
|
||
Voors AA,
|
||
Emmens JE</span><br />
|
||
<span class="medgenPMjournal">Eur Heart J</span>
|
||
2023 Feb 1;44(5):368-380.
|
||
doi: 10.1093/eurheartj/ehac528.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36148485" target="_blank">36148485</a><a href="/pmc/articles/PMC9890244" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31744130">Towards Point-of-Care Heart Failure Diagnostic Platforms: BNP and NT-proBNP Biosensors.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Alawieh H,
|
||
Chemaly TE,
|
||
Alam S,
|
||
Khraiche M</span><br />
|
||
<span class="medgenPMjournal">Sensors (Basel)</span>
|
||
2019 Nov 16;19(22)
|
||
doi: 10.3390/s19225003.
|
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<span class="bold">PMID: </span><a href="/pubmed/31744130" target="_blank">31744130</a><a href="/pmc/articles/PMC6891483" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Increased%20circulating%20NT-proBNP%20concentration%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (109)</a></div><h3 class="subhead">Therapy</h3>
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<div class="nl"><a target="_blank" href="/pubmed/38299345">Proteomic Associations of NT-proBNP (N-Terminal Pro-B-Type Natriuretic Peptide) in Heart Failure With Preserved Ejection Fraction.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Azzo JD,
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Dib MJ,
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Zagkos L,
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Zhao L,
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Wang Z,
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Chang CP,
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Ebert C,
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Salman O,
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Gan S,
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Zamani P,
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Cohen JB,
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van Empel V,
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Richards AM,
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Javaheri A,
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Mann DL,
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Rietzschel ER,
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Schafer PH,
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Seiffert DA,
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Gill D,
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Burgess S,
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Ramirez-Valle F,
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Gordon DA,
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Cappola TP,
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Chirinos JA</span><br />
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<span class="medgenPMjournal">Circ Heart Fail</span>
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2024 Feb;17(2):e011146.
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Epub 2024 Feb 1
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doi: 10.1161/CIRCHEARTFAILURE.123.011146.
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<span class="bold">PMID: </span><a href="/pubmed/38299345" target="_blank">38299345</a><a href="/pmc/articles/PMC7615693" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/37603600">Cardiorenal Biomarkers, Canagliflozin, and Outcomes in Diabetic Kidney Disease: The CREDENCE Trial.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Januzzi JL,
|
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Mohebi R,
|
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Liu Y,
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Sattar N,
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Heerspink HJL,
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Tefera E,
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Vaduganathan M,
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Butler J,
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Yavin Y,
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Li J,
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Pollock CA,
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Perkovic V,
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Neal B,
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Hansen MK</span><br />
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<span class="medgenPMjournal">Circulation</span>
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2023 Aug 22;148(8):651-660.
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Epub 2023 Aug 21
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doi: 10.1161/CIRCULATIONAHA.123.065251.
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<span class="bold">PMID: </span><a href="/pubmed/37603600" target="_blank">37603600</a></div>
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||
<div class="nl"><a target="_blank" href="/pubmed/37323111">Evolocumab has no effects on heart failure with reduced ejection fraction injury biomarkers: The EVO-HF trial.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Bayes-Genis A,
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Lupón J,
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Revuelta-Lopez E,
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Llibre C,
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Gastelurrutia P,
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Domingo M,
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Cediel G,
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Codina P,
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Santiago-Vacas E,
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Rangel-Sousa D,
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Fernández-Cisnal A,
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Miñana G,
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Mollar A,
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Núñez J</span><br />
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<span class="medgenPMjournal">Eur J Heart Fail</span>
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2023 Aug;25(8):1439-1443.
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Epub 2023 Jun 27
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doi: 10.1002/ejhf.2932.
|
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<span class="bold">PMID: </span><a href="/pubmed/37323111" target="_blank">37323111</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30846338">B-Type Natriuretic Peptide During Treatment With Sacubitril/Valsartan: The PARADIGM-HF Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Myhre PL,
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Vaduganathan M,
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Claggett B,
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Packer M,
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Desai AS,
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Rouleau JL,
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Zile MR,
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Swedberg K,
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Lefkowitz M,
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Shi V,
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McMurray JJV,
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Solomon SD</span><br />
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<span class="medgenPMjournal">J Am Coll Cardiol</span>
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2019 Mar 26;73(11):1264-1272.
|
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Epub 2019 Mar 4
|
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doi: 10.1016/j.jacc.2019.01.018.
|
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<span class="bold">PMID: </span><a href="/pubmed/30846338" target="_blank">30846338</a><a href="/pmc/articles/PMC7955687" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
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|
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<div class="nl"><a target="_blank" href="/pubmed/17596101">Clinical pharmacology of levosimendan.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Antila S,
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Sundberg S,
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Lehtonen LA</span><br />
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<span class="medgenPMjournal">Clin Pharmacokinet</span>
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2007;46(7):535-52.
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doi: 10.2165/00003088-200746070-00001.
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<span class="bold">PMID: </span><a href="/pubmed/17596101" target="_blank">17596101</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Increased%20circulating%20NT-proBNP%20concentration%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (50)</a></div><h3 class="subhead">Prognosis</h3>
|
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<div class="nl"><a target="_blank" href="/pubmed/39540306">A Proteomics-Based Approach for Prediction of Different Cardiovascular Diseases and Dementia.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Ho FK,
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Mark PB,
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Lees JS,
|
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Pell JP,
|
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Strawbridge RJ,
|
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Kimenai DM,
|
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Mills NL,
|
||
Woodward M,
|
||
McMurray JJV,
|
||
Sattar N,
|
||
Welsh P</span><br />
|
||
<span class="medgenPMjournal">Circulation</span>
|
||
2025 Feb 4;151(5):277-287.
|
||
Epub 2024 Nov 14
|
||
doi: 10.1161/CIRCULATIONAHA.124.070454.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39540306" target="_blank">39540306</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37603600">Cardiorenal Biomarkers, Canagliflozin, and Outcomes in Diabetic Kidney Disease: The CREDENCE Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Januzzi JL,
|
||
Mohebi R,
|
||
Liu Y,
|
||
Sattar N,
|
||
Heerspink HJL,
|
||
Tefera E,
|
||
Vaduganathan M,
|
||
Butler J,
|
||
Yavin Y,
|
||
Li J,
|
||
Pollock CA,
|
||
Perkovic V,
|
||
Neal B,
|
||
Hansen MK</span><br />
|
||
<span class="medgenPMjournal">Circulation</span>
|
||
2023 Aug 22;148(8):651-660.
|
||
Epub 2023 Aug 21
|
||
doi: 10.1161/CIRCULATIONAHA.123.065251.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37603600" target="_blank">37603600</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37184278">Increased circulating phenylacetylglutamine concentration elevates the predictive value of cardiovascular event risk in heart failure patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wei H,
|
||
Wu J,
|
||
Wang H,
|
||
Huang J,
|
||
Li C,
|
||
Zhang Y,
|
||
Song Y,
|
||
Zhou Z,
|
||
Sun Y,
|
||
Xiao L,
|
||
Peng L,
|
||
Chen C,
|
||
Zhao C,
|
||
Wang DW</span><br />
|
||
<span class="medgenPMjournal">J Intern Med</span>
|
||
2023 Oct;294(4):515-530.
|
||
Epub 2023 May 30
|
||
doi: 10.1111/joim.13653.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37184278" target="_blank">37184278</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31744130">Towards Point-of-Care Heart Failure Diagnostic Platforms: BNP and NT-proBNP Biosensors.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Alawieh H,
|
||
Chemaly TE,
|
||
Alam S,
|
||
Khraiche M</span><br />
|
||
<span class="medgenPMjournal">Sensors (Basel)</span>
|
||
2019 Nov 16;19(22)
|
||
doi: 10.3390/s19225003.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31744130" target="_blank">31744130</a><a href="/pmc/articles/PMC6891483" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30846338">B-Type Natriuretic Peptide During Treatment With Sacubitril/Valsartan: The PARADIGM-HF Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Myhre PL,
|
||
Vaduganathan M,
|
||
Claggett B,
|
||
Packer M,
|
||
Desai AS,
|
||
Rouleau JL,
|
||
Zile MR,
|
||
Swedberg K,
|
||
Lefkowitz M,
|
||
Shi V,
|
||
McMurray JJV,
|
||
Solomon SD</span><br />
|
||
<span class="medgenPMjournal">J Am Coll Cardiol</span>
|
||
2019 Mar 26;73(11):1264-1272.
|
||
Epub 2019 Mar 4
|
||
doi: 10.1016/j.jacc.2019.01.018.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30846338" target="_blank">30846338</a><a href="/pmc/articles/PMC7955687" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Increased%20circulating%20NT-proBNP%20concentration%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (112)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39540306">A Proteomics-Based Approach for Prediction of Different Cardiovascular Diseases and Dementia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ho FK,
|
||
Mark PB,
|
||
Lees JS,
|
||
Pell JP,
|
||
Strawbridge RJ,
|
||
Kimenai DM,
|
||
Mills NL,
|
||
Woodward M,
|
||
McMurray JJV,
|
||
Sattar N,
|
||
Welsh P</span><br />
|
||
<span class="medgenPMjournal">Circulation</span>
|
||
2025 Feb 4;151(5):277-287.
|
||
Epub 2024 Nov 14
|
||
doi: 10.1161/CIRCULATIONAHA.124.070454.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39540306" target="_blank">39540306</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37603600">Cardiorenal Biomarkers, Canagliflozin, and Outcomes in Diabetic Kidney Disease: The CREDENCE Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Januzzi JL,
|
||
Mohebi R,
|
||
Liu Y,
|
||
Sattar N,
|
||
Heerspink HJL,
|
||
Tefera E,
|
||
Vaduganathan M,
|
||
Butler J,
|
||
Yavin Y,
|
||
Li J,
|
||
Pollock CA,
|
||
Perkovic V,
|
||
Neal B,
|
||
Hansen MK</span><br />
|
||
<span class="medgenPMjournal">Circulation</span>
|
||
2023 Aug 22;148(8):651-660.
|
||
Epub 2023 Aug 21
|
||
doi: 10.1161/CIRCULATIONAHA.123.065251.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37603600" target="_blank">37603600</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37184278">Increased circulating phenylacetylglutamine concentration elevates the predictive value of cardiovascular event risk in heart failure patients.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Wei H,
|
||
Wu J,
|
||
Wang H,
|
||
Huang J,
|
||
Li C,
|
||
Zhang Y,
|
||
Song Y,
|
||
Zhou Z,
|
||
Sun Y,
|
||
Xiao L,
|
||
Peng L,
|
||
Chen C,
|
||
Zhao C,
|
||
Wang DW</span><br />
|
||
<span class="medgenPMjournal">J Intern Med</span>
|
||
2023 Oct;294(4):515-530.
|
||
Epub 2023 May 30
|
||
doi: 10.1111/joim.13653.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37184278" target="_blank">37184278</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/30846338">B-Type Natriuretic Peptide During Treatment With Sacubitril/Valsartan: The PARADIGM-HF Trial.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Myhre PL,
|
||
Vaduganathan M,
|
||
Claggett B,
|
||
Packer M,
|
||
Desai AS,
|
||
Rouleau JL,
|
||
Zile MR,
|
||
Swedberg K,
|
||
Lefkowitz M,
|
||
Shi V,
|
||
McMurray JJV,
|
||
Solomon SD</span><br />
|
||
<span class="medgenPMjournal">J Am Coll Cardiol</span>
|
||
2019 Mar 26;73(11):1264-1272.
|
||
Epub 2019 Mar 4
|
||
doi: 10.1016/j.jacc.2019.01.018.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30846338" target="_blank">30846338</a><a href="/pmc/articles/PMC7955687" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/28242284">NT-proBNP is increased in differentiated thyroid carcinoma patients and may predict cardiovascular risk.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Klein Hesselink EN,
|
||
van der Horst-Schrivers ANA,
|
||
van der Horst ICC,
|
||
Bakker SJL,
|
||
Muller Kobold AC,
|
||
Brouwers AH,
|
||
de Bock GH,
|
||
Gietema JA,
|
||
Dullaart RPF,
|
||
Links TP,
|
||
Lefrandt JD</span><br />
|
||
<span class="medgenPMjournal">Clin Biochem</span>
|
||
2017 Aug;50(12):696-702.
|
||
Epub 2017 Feb 27
|
||
doi: 10.1016/j.clinbiochem.2017.02.020.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28242284" target="_blank">28242284</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Increased%20circulating%20NT-proBNP%20concentration%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (115)</a></div></div>
|
||
</div>
|
||
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|
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