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<!--
|
||
UID=124638
|
||
ConceptID=C0279636
|
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Childhood Acute Myeloid Leukemia with Maturation</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>124638</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0279636</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Neoplastic Process</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Childhood Acute M2 Leukemia; Childhood Acute Myeloblastic Leukemia with Maturation; Childhood Acute Myeloblastic Leukemia with Maturation (M2); Childhood Acute Myelogenous Leukemia with Maturation; M2 Childhood Acute Myeloblastic Leukemia with Maturation; M2 Childhood Acute Myelogenous Leukemia; M2 Childhood Acute Myelogenous Leukemia with Maturation; M2 Childhood Acute Myeloid Leukemia with Maturation; M2 Pediatric Acute Myeloblastic Leukemia with Maturation; M2 Pediatric Acute Myelogenous Leukemia; M2 Pediatric Acute Myelogenous Leukemia with Maturation; M2 Pediatric Acute Myeloid Leukemia with Maturation; M2 Pediatric AGL; Pediatric Acute M2 Leukemia; Pediatric Acute Myeloblastic Leukemia with Maturation; Pediatric Acute Myelogenous Leukemia with Maturation; Pediatric Acute Myeloid Leukemia with Maturation</td></tr>
|
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">An acute myeloid leukemia with maturation occurring in children. [from <a title="NCI Thesaurus" href="http://ncit.nci.nih.gov" class="defSource" target="_blank">NCI</a>]</div>
|
||
</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Childhood Acute Myeloid Leukemia with Maturation</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/5483" ref="tree=MeSH" title="MedGen record for Hematologic disorder">Hematologic disorder</a></span><ul><li><span class="TLline"><a href="/medgen/138213" ref="tree=MeSH" title="MedGen record for Hematologic neoplasm">Hematologic neoplasm</a></span><ul><li><span class="TLline"><a href="/medgen/9725" ref="tree=MeSH" title="MedGen record for Leukemia">Leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/43225" ref="tree=MeSH" title="MedGen record for Acute leukemia">Acute leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/9730" ref="tree=MeSH" title="MedGen record for Acute myeloid leukemia">Acute myeloid leukemia</a></span><ul><li><span class="TLline"><a href="/medgen/361829" ref="tree=MeSH" title="MedGen record for Acute myeloblastic leukemia with maturation">Acute myeloblastic leukemia with maturation</a></span><ul><li><span class="matched_ds">Childhood Acute Myeloid Leukemia with Maturation</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
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<div class="portlet mgSection" id="ID_105">
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||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/30504192">Improving diagnosis and treatment of acute childhood leukemia in Uganda: impact of flow cytometry.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Namazzi R,
|
||
Gaikwad A,
|
||
Wasswa P,
|
||
Cubbage M,
|
||
Kambugu JB,
|
||
Kasirye P,
|
||
Geriga F,
|
||
Allen C,
|
||
Lubega J</span><br />
|
||
<span class="medgenPMjournal">Blood Adv</span>
|
||
2018 Nov 30;2(Suppl 1):21-23.
|
||
doi: 10.1182/bloodadvances.2018GS112620.
|
||
<span class="bold">PMID: </span><a href="/pubmed/30504192" target="_blank">30504192</a><a href="/pmc/articles/PMC6438277" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/22879540">Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Creutzig U,
|
||
van den Heuvel-Eibrink MM,
|
||
Gibson B,
|
||
Dworzak MN,
|
||
Adachi S,
|
||
de Bont E,
|
||
Harbott J,
|
||
Hasle H,
|
||
Johnston D,
|
||
Kinoshita A,
|
||
Lehrnbecher T,
|
||
Leverger G,
|
||
Mejstrikova E,
|
||
Meshinchi S,
|
||
Pession A,
|
||
Raimondi SC,
|
||
Sung L,
|
||
Stary J,
|
||
Zwaan CM,
|
||
Kaspers GJ,
|
||
Reinhardt D;
|
||
AML Committee of the International BFM Study Group</span><br />
|
||
<span class="medgenPMjournal">Blood</span>
|
||
2012 Oct 18;120(16):3187-205.
|
||
Epub 2012 Aug 9
|
||
doi: 10.1182/blood-2012-03-362608.
|
||
<span class="bold">PMID: </span><a href="/pubmed/22879540" target="_blank">22879540</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/8793274">Diagnosis and treatment of acute myelogenous leukemia in childhood.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Creutzig U</span><br />
|
||
<span class="medgenPMjournal">Crit Rev Oncol Hematol</span>
|
||
1996 Apr;22(3):183-96.
|
||
doi: 10.1016/1040-8428(96)00195-3.
|
||
<span class="bold">PMID: </span><a href="/pubmed/8793274" target="_blank">8793274</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(childhood%20acute%20myeloid%20leukemia%20with%20maturation)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (206)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37890156">Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Barajas JM,
|
||
Rasouli M,
|
||
Umeda M,
|
||
Hiltenbrand R,
|
||
Abdelhamed S,
|
||
Mohnani R,
|
||
Arthur B,
|
||
Westover T,
|
||
Thomas ME 3rd,
|
||
Ashtiani M,
|
||
Janke LJ,
|
||
Xu B,
|
||
Chang TC,
|
||
Rosikiewicz W,
|
||
Xiong E,
|
||
Rolle C,
|
||
Low J,
|
||
Krishan R,
|
||
Song G,
|
||
Walsh MP,
|
||
Ma J,
|
||
Rubnitz JE,
|
||
Iacobucci I,
|
||
Chen T,
|
||
Krippner-Heidenreich A,
|
||
Zwaan CM,
|
||
Heidenreich O,
|
||
Klco JM</span><br />
|
||
<span class="medgenPMjournal">Blood</span>
|
||
2024 Feb 15;143(7):619-630.
|
||
doi: 10.1182/blood.2023021359.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37890156" target="_blank">37890156</a><a href="/pmc/articles/PMC10873536" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/37686807">Early Life Nutrition Factors and Risk of Acute Leukemia in Children: Systematic Review and Meta-Analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kintossou AK,
|
||
Blanco-Lopez J,
|
||
Iguacel I,
|
||
Pisanu S,
|
||
Almeida CCB,
|
||
Steliarova-Foucher E,
|
||
Sierens C,
|
||
Gunter MJ,
|
||
Ladas EJ,
|
||
Barr RD,
|
||
Van Herck K,
|
||
Kozlakidis Z,
|
||
Huybrechts I</span><br />
|
||
<span class="medgenPMjournal">Nutrients</span>
|
||
2023 Aug 29;15(17)
|
||
doi: 10.3390/nu15173775.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37686807" target="_blank">37686807</a><a href="/pmc/articles/PMC10489830" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36861399">Relapsed pediatric acute myeloid leukaemia: state-of-the-art in 2023.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Egan G,
|
||
Tasian SK</span><br />
|
||
<span class="medgenPMjournal">Haematologica</span>
|
||
2023 Sep 1;108(9):2275-2288.
|
||
doi: 10.3324/haematol.2022.281106.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36861399" target="_blank">36861399</a><a href="/pmc/articles/PMC10483345" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31815781">Pediatric acute myeloid leukemia: updates on biology, risk stratification, and therapy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Elgarten CW,
|
||
Aplenc R</span><br />
|
||
<span class="medgenPMjournal">Curr Opin Pediatr</span>
|
||
2020 Feb;32(1):57-66.
|
||
doi: 10.1097/MOP.0000000000000855.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31815781" target="_blank">31815781</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29438960">How I treat myelodysplastic syndromes of childhood.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Locatelli F,
|
||
Strahm B</span><br />
|
||
<span class="medgenPMjournal">Blood</span>
|
||
2018 Mar 29;131(13):1406-1414.
|
||
Epub 2018 Feb 8
|
||
doi: 10.1182/blood-2017-09-765214.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29438960" target="_blank">29438960</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Childhood%20Acute%20Myeloid%20Leukemia%20with%20Maturation%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1508)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/37890156">Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Barajas JM,
|
||
Rasouli M,
|
||
Umeda M,
|
||
Hiltenbrand R,
|
||
Abdelhamed S,
|
||
Mohnani R,
|
||
Arthur B,
|
||
Westover T,
|
||
Thomas ME 3rd,
|
||
Ashtiani M,
|
||
Janke LJ,
|
||
Xu B,
|
||
Chang TC,
|
||
Rosikiewicz W,
|
||
Xiong E,
|
||
Rolle C,
|
||
Low J,
|
||
Krishan R,
|
||
Song G,
|
||
Walsh MP,
|
||
Ma J,
|
||
Rubnitz JE,
|
||
Iacobucci I,
|
||
Chen T,
|
||
Krippner-Heidenreich A,
|
||
Zwaan CM,
|
||
Heidenreich O,
|
||
Klco JM</span><br />
|
||
<span class="medgenPMjournal">Blood</span>
|
||
2024 Feb 15;143(7):619-630.
|
||
doi: 10.1182/blood.2023021359.
|
||
<span class="bold">PMID: </span><a href="/pubmed/37890156" target="_blank">37890156</a><a href="/pmc/articles/PMC10873536" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36861399">Relapsed pediatric acute myeloid leukaemia: state-of-the-art in 2023.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Egan G,
|
||
Tasian SK</span><br />
|
||
<span class="medgenPMjournal">Haematologica</span>
|
||
2023 Sep 1;108(9):2275-2288.
|
||
doi: 10.3324/haematol.2022.281106.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36861399" target="_blank">36861399</a><a href="/pmc/articles/PMC10483345" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36130297">Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Duncavage EJ,
|
||
Bagg A,
|
||
Hasserjian RP,
|
||
DiNardo CD,
|
||
Godley LA,
|
||
Iacobucci I,
|
||
Jaiswal S,
|
||
Malcovati L,
|
||
Vannucchi AM,
|
||
Patel KP,
|
||
Arber DA,
|
||
Arcila ME,
|
||
Bejar R,
|
||
Berliner N,
|
||
Borowitz MJ,
|
||
Branford S,
|
||
Brown AL,
|
||
Cargo CA,
|
||
Döhner H,
|
||
Falini B,
|
||
Garcia-Manero G,
|
||
Haferlach T,
|
||
Hellström-Lindberg E,
|
||
Kim AS,
|
||
Klco JM,
|
||
Komrokji R,
|
||
Lee-Cheun Loh M,
|
||
Loghavi S,
|
||
Mullighan CG,
|
||
Ogawa S,
|
||
Orazi A,
|
||
Papaemmanuil E,
|
||
Reiter A,
|
||
Ross DM,
|
||
Savona M,
|
||
Shimamura A,
|
||
Skoda RC,
|
||
Solé F,
|
||
Stone RM,
|
||
Tefferi A,
|
||
Walter MJ,
|
||
Wu D,
|
||
Ebert BL,
|
||
Cazzola M</span><br />
|
||
<span class="medgenPMjournal">Blood</span>
|
||
2022 Nov 24;140(21):2228-2247.
|
||
doi: 10.1182/blood.2022015853.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36130297" target="_blank">36130297</a><a href="/pmc/articles/PMC10488320" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31815781">Pediatric acute myeloid leukemia: updates on biology, risk stratification, and therapy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Elgarten CW,
|
||
Aplenc R</span><br />
|
||
<span class="medgenPMjournal">Curr Opin Pediatr</span>
|
||
2020 Feb;32(1):57-66.
|
||
doi: 10.1097/MOP.0000000000000855.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31815781" target="_blank">31815781</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/29438960">How I treat myelodysplastic syndromes of childhood.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Locatelli F,
|
||
Strahm B</span><br />
|
||
<span class="medgenPMjournal">Blood</span>
|
||
2018 Mar 29;131(13):1406-1414.
|
||
Epub 2018 Feb 8
|
||
doi: 10.1182/blood-2017-09-765214.
|
||
<span class="bold">PMID: </span><a href="/pubmed/29438960" target="_blank">29438960</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Childhood%20Acute%20Myeloid%20Leukemia%20with%20Maturation%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1383)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/39333315">Cytokine-mediated CAR T therapy resistance in AML.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bhagwat AS,
|
||
Torres L,
|
||
Shestova O,
|
||
Shestov M,
|
||
Mellors PW,
|
||
Fisher HR,
|
||
Farooki SN,
|
||
Frost BF,
|
||
Loken MR,
|
||
Gaymon AL,
|
||
Frazee D,
|
||
Rogal W,
|
||
Frey N,
|
||
Hexner EO,
|
||
Luger SM,
|
||
Loren AW,
|
||
Martin ME,
|
||
McCurdy SR,
|
||
Perl AE,
|
||
Stadtmauer EA,
|
||
Brogdon JL,
|
||
Fraietta JA,
|
||
Hwang WT,
|
||
Siegel DL,
|
||
Plesa G,
|
||
Aplenc R,
|
||
Porter DL,
|
||
June CH,
|
||
Gill SI</span><br />
|
||
<span class="medgenPMjournal">Nat Med</span>
|
||
2024 Dec;30(12):3697-3708.
|
||
Epub 2024 Sep 27
|
||
doi: 10.1038/s41591-024-03271-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/39333315" target="_blank">39333315</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36861399">Relapsed pediatric acute myeloid leukaemia: state-of-the-art in 2023.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Egan G,
|
||
Tasian SK</span><br />
|
||
<span class="medgenPMjournal">Haematologica</span>
|
||
2023 Sep 1;108(9):2275-2288.
|
||
doi: 10.3324/haematol.2022.281106.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36861399" target="_blank">36861399</a><a href="/pmc/articles/PMC10483345" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36799929">A global study for acute myeloid leukemia with RARG rearrangement.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Zhu HH,
|
||
Qin YZ,
|
||
Zhang ZL,
|
||
Liu YJ,
|
||
Wen LJ,
|
||
You MJ,
|
||
Zhang C,
|
||
Such E,
|
||
Luo H,
|
||
Yuan HJ,
|
||
Zhou HS,
|
||
Liu HX,
|
||
Xu R,
|
||
Li J,
|
||
Li JH,
|
||
Hao JP,
|
||
Jin J,
|
||
Yu L,
|
||
Zhang JY,
|
||
Liu LP,
|
||
Zhang LP,
|
||
Huang RB,
|
||
Shen SH,
|
||
Gao SJ,
|
||
Wang W,
|
||
Yan XJ,
|
||
Zhang XY,
|
||
Du X,
|
||
Chu XX,
|
||
Yu YF,
|
||
Wang Y,
|
||
Mi YC,
|
||
Lu Y,
|
||
Cai Z,
|
||
Su Z,
|
||
Taussig DC,
|
||
MacMahon S,
|
||
Ball ED,
|
||
Wang HY,
|
||
Welch JS,
|
||
Yin CC,
|
||
Borthakur G,
|
||
Sanz MA,
|
||
Kantarjian HM,
|
||
Huang JY,
|
||
Hu J,
|
||
Chen SN</span><br />
|
||
<span class="medgenPMjournal">Blood Adv</span>
|
||
2023 Jul 11;7(13):2972-2982.
|
||
doi: 10.1182/bloodadvances.2022008364.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36799929" target="_blank">36799929</a><a href="/pmc/articles/PMC10320208" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/36099049">Immune dysfunction signatures predict outcomes and define checkpoint blockade-unresponsive microenvironments in acute myeloid leukemia.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rutella S,
|
||
Vadakekolathu J,
|
||
Mazziotta F,
|
||
Reeder S,
|
||
Yau TO,
|
||
Mukhopadhyay R,
|
||
Dickins B,
|
||
Altmann H,
|
||
Kramer M,
|
||
Knaus HA,
|
||
Blazar BR,
|
||
Radojcic V,
|
||
Zeidner JF,
|
||
Arruda A,
|
||
Wang B,
|
||
Abbas HA,
|
||
Minden MD,
|
||
Tasian SK,
|
||
Bornhäuser M,
|
||
Gojo I,
|
||
Luznik L</span><br />
|
||
<span class="medgenPMjournal">J Clin Invest</span>
|
||
2022 Nov 1;132(21)
|
||
doi: 10.1172/JCI159579.
|
||
<span class="bold">PMID: </span><a href="/pubmed/36099049" target="_blank">36099049</a><a href="/pmc/articles/PMC9621145" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/31815781">Pediatric acute myeloid leukemia: updates on biology, risk stratification, and therapy.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Elgarten CW,
|
||
Aplenc R</span><br />
|
||
<span class="medgenPMjournal">Curr Opin Pediatr</span>
|
||
2020 Feb;32(1):57-66.
|
||
doi: 10.1097/MOP.0000000000000855.
|
||
<span class="bold">PMID: </span><a href="/pubmed/31815781" target="_blank">31815781</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Childhood%20Acute%20Myeloid%20Leukemia%20with%20Maturation%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1051)</a></div><h3 class="subhead">Prognosis</h3>
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<div class="nl"><a target="_blank" href="/pubmed/36799929">A global study for acute myeloid leukemia with RARG rearrangement.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Zhu HH,
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Childhood%20Acute%20Myeloid%20Leukemia%20with%20Maturation%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1277)</a></div><h3 class="subhead">Clinical prediction guides</h3>
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<div class="nl"><a target="_blank" href="/pubmed/39333315">Cytokine-mediated CAR T therapy resistance in AML.</a></div>
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Hexner EO,
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Loren AW,
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Martin ME,
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McCurdy SR,
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Perl AE,
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Stadtmauer EA,
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Brogdon JL,
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<span class="bold">PMID: </span><a href="/pubmed/39333315" target="_blank">39333315</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/38714197">Mapping the cellular biogeography of human bone marrow niches using single-cell transcriptomics and proteomic imaging.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Bandyopadhyay S,
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Duffy MP,
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Ahn KJ,
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Sussman JH,
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Pang M,
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Smith D,
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Duncan G,
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Zhang I,
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Huang J,
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Lin Y,
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Xiong B,
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Imtiaz T,
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Chen CH,
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Thadi A,
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Chen C,
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Xu J,
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Reichart M,
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Martinez Z,
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Diorio C,
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Chen C,
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Pillai V,
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Snaith O,
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Oldridge D,
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Bhattacharyya S,
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Maillard I,
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Carroll M,
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Nelson C,
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Qin L,
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Tan K</span><br />
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<span class="medgenPMjournal">Cell</span>
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2024 Jun 6;187(12):3120-3140.e29.
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Epub 2024 May 6
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doi: 10.1016/j.cell.2024.04.013.
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<span class="bold">PMID: </span><a href="/pubmed/38714197" target="_blank">38714197</a><a href="/pmc/articles/PMC11162340" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/30391350">RUNX1 and the endothelial origin of blood.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Gao L,
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Tober J,
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<span class="bold">PMID: </span><a href="/pubmed/30391350" target="_blank">30391350</a><a href="/pmc/articles/PMC6494457" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/29438960">How I treat myelodysplastic syndromes of childhood.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Locatelli F,
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Strahm B</span><br />
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<span class="medgenPMjournal">Blood</span>
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2018 Mar 29;131(13):1406-1414.
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<span class="bold">PMID: </span><a href="/pubmed/29438960" target="_blank">29438960</a></div>
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<div class="nl"><a target="_blank" href="/pubmed/26980726">Comprehensive mutational profiling of core binding factor acute myeloid leukemia.</a></div>
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Marceau-Renaut A,
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Bucci M,
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Geffroy S,
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Lapillonne H,
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Figeac M,
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Celli-Lebras K,
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Micol JB,
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Abdel-Wahab O,
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<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Childhood%20Acute%20Myeloid%20Leukemia%20with%20Maturation%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (769)</a></div></div>
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<div class="portlet mgSection" id="ID_104">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln">
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||
<div class="nl"><a target="_blank" href="/pubmed/37686807">Early Life Nutrition Factors and Risk of Acute Leukemia in Children: Systematic Review and Meta-Analysis.</a></div>
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<div class="portlet_content ln"><span class="medgenPMauthor">Kintossou AK,
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Blanco-Lopez J,
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Iguacel I,
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Pisanu S,
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Almeida CCB,
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Steliarova-Foucher E,
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Sierens C,
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Gunter MJ,
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Ladas EJ,
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Barr RD,
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Van Herck K,
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Kozlakidis Z,
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Huybrechts I</span><br />
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<span class="medgenPMjournal">Nutrients</span>
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2023 Aug 29;15(17)
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doi: 10.3390/nu15173775.
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<span class="bold">PMID: </span><a href="/pubmed/37686807" target="_blank">37686807</a><a href="/pmc/articles/PMC10489830" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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|
||
<div class="nl"><a target="_blank" href="/pubmed/36162822">Dexrazoxane for preventing or reducing cardiotoxicity in adults and children with cancer receiving anthracyclines.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">de Baat EC,
|
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Mulder RL,
|
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Armenian S,
|
||
Feijen EA,
|
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Grotenhuis H,
|
||
Hudson MM,
|
||
Mavinkurve-Groothuis AM,
|
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Kremer LC,
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van Dalen EC</span><br />
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<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
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2022 Sep 27;9(9):CD014638.
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doi: 10.1002/14651858.CD014638.pub2.
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<span class="bold">PMID: </span><a href="/pubmed/36162822" target="_blank">36162822</a><a href="/pmc/articles/PMC9512638" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/34380208">Exposure to pesticides and childhood leukemia risk: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Karalexi MA,
|
||
Tagkas CF,
|
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Markozannes G,
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Tseretopoulou X,
|
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Hernández AF,
|
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Schüz J,
|
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Halldorsson TI,
|
||
Psaltopoulou T,
|
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Petridou ET,
|
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Tzoulaki I,
|
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Ntzani EE</span><br />
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<span class="medgenPMjournal">Environ Pollut</span>
|
||
2021 Sep 15;285:117376.
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||
Epub 2021 May 18
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||
doi: 10.1016/j.envpol.2021.117376.
|
||
<span class="bold">PMID: </span><a href="/pubmed/34380208" target="_blank">34380208</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/33706635">Measurable residual disease in pediatric acute myeloid leukemia: a systematic review.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Segerink WH,
|
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de Haas V,
|
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Kaspers GJL</span><br />
|
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<span class="medgenPMjournal">Expert Rev Anticancer Ther</span>
|
||
2021 Apr;21(4):451-459.
|
||
Epub 2021 Mar 11
|
||
doi: 10.1080/14737140.2021.1860763.
|
||
<span class="bold">PMID: </span><a href="/pubmed/33706635" target="_blank">33706635</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/32073908">Nutrition of Children With Cancer in Brazil: A Systematic Review.</a></div>
|
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<div class="portlet_content ln"><span class="medgenPMauthor">Viani K,
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Albuquerque L,
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Barr RD,
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Ladas EJ</span><br />
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<span class="medgenPMjournal">JCO Glob Oncol</span>
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2020 Feb;6:242-259.
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doi: 10.1200/JGO.19.00285.
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<span class="bold">PMID: </span><a href="/pubmed/32073908" target="_blank">32073908</a><a href="/pmc/articles/PMC7051796" target="_blank" class="PubMedFree">Free PMC Article</a></div>
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||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Childhood%20Acute%20Myeloid%20Leukemia%20with%20Maturation%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (20)</a></div></div>
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