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<!--
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||
UID=105466
|
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ConceptID=C0520878
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-->
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<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Shortened PR interval</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>105466</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0520878</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonym:</td>
|
||
<td>Short PR interval</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Shortened PR interval (49578007)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
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<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0005165">HP:0005165</a></td></tr>
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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||
<div class="portlet_content ln">Reduced time for the PR interval (beginning of the P wave to the beginning of the QRS complex). In adults, normal values are 120 to 200 ms long. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Shortened PR interval</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/1715859" ref="tree=MeSH" title="MedGen record for Abnormal Cardiac Study">Abnormal Cardiac Study</a></span><ul><li><span class="TLline"><a href="/medgen/105507" ref="tree=MeSH" title="MedGen record for Abnormal EKG">Abnormal EKG</a></span><ul><li><span class="TLline"><a href="/medgen/1634800" ref="tree=MeSH" title="MedGen record for Abnormal PR interval">Abnormal PR interval</a></span><ul><li><span class="matched_ds">Shortened PR interval</span></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_5340"><div><strong>Glycogen storage disease, type II</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>5340</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0017921</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Pompe disease is classified by age of onset, organ involvement, severity, and rate of progression. Infantile-onset Pompe disease (IOPD; individuals with onset before age 12 months with cardiomyopathy) may be apparent in utero but more typically onset is at the median age of four months with hypotonia, generalized muscle weakness, feeding difficulties, failure to thrive, respiratory distress, and hypertrophic cardiomyopathy. Without treatment by enzyme replacement therapy (ERT), IOPD commonly results in death by age two years from progressive left ventricular outflow obstruction and respiratory insufficiency. Late-onset Pompe disease (LOPD; including: (a) individuals with onset before age 12 months without cardiomyopathy; and (b) all individuals with onset after age 12 months) is characterized by proximal muscle weakness and respiratory insufficiency; clinically significant cardiac involvement is uncommon.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/5340">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_12162"><div><strong>Wolff-Parkinson-White pattern</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>12162</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0043202</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Wolff-Parkinson-White syndrome is a condition characterized by abnormal electrical pathways in the heart that cause a disruption of the heart's normal rhythm (arrhythmia).\n\nThe heartbeat is controlled by electrical signals that move through the heart in a highly coordinated way. A specialized cluster of cells called the atrioventricular node conducts electrical impulses from the heart's upper chambers (the atria) to the lower chambers (the ventricles). Impulses move through the atrioventricular node during each heartbeat, stimulating the ventricles to contract slightly later than the atria.\n\nPeople with Wolff-Parkinson-White syndrome are born with an extra connection in the heart, called an accessory pathway, that allows electrical signals to bypass the atrioventricular node and move from the atria to the ventricles faster than usual. The accessory pathway may also transmit electrical impulses abnormally from the ventricles back to the atria. This extra connection can disrupt the coordinated movement of electrical signals through the heart, leading to an abnormally fast heartbeat (tachycardia) and other changes in heart rhythm. Resulting symptoms include dizziness, a sensation of fluttering or pounding in the chest (palpitations), shortness of breath, and fainting (syncope). In rare cases, arrhythmias associated with Wolff-Parkinson-White syndrome can lead to cardiac arrest and sudden death. The most common arrhythmia associated with Wolff-Parkinson-White syndrome is called paroxysmal supraventricular tachycardia.\n\nComplications of Wolff-Parkinson-White syndrome can occur at any age, although some individuals born with an accessory pathway in the heart never experience any health problems associated with the condition.\n\nWolff-Parkinson-White syndrome often occurs with other structural abnormalities of the heart or underlying heart disease. The most common heart defect associated with the condition is Ebstein anomaly, which affects the valve that allows blood to flow from the right atrium to the right ventricle (the tricuspid valve). Additionally, the heart rhythm problems associated with Wolff-Parkinson-White syndrome can be a component of several other genetic syndromes, including hypokalemic periodic paralysis (a condition that causes episodes of extreme muscle weakness), Pompe disease (a disorder characterized by the storage of excess glycogen), Danon disease (a condition that weakens the heart and skeletal muscles and causes intellectual disability), and tuberous sclerosis complex (a condition that results in the growth of noncancerous tumors in many parts of the body).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/12162">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_331466"><div><strong>Hypertrophic cardiomyopathy 6</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>331466</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1833236</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Mutations in the PRKAG2 gene (602743) give rise to a moderate, essentially heart-specific, nonlysosomal glycogenosis with clinical onset typically in late adolescence or in the third decade of life, ventricular pre-excitation predisposing to supraventricular arrhythmias, mild to severe cardiac hypertrophy, enhanced risk of sudden cardiac death in midlife, and autosomal dominant inheritance with full penetrance (summary by Burwinkel et al., 2005).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/331466">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_337919"><div><strong>Lethal congenital glycogen storage disease of heart</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>337919</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1849813</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A rare glycogen storage disease with fetal or neonatal onset of severe cardiomyopathy with non-lysosomal glycogen accumulation and fatal outcome in infancy. Patients present with massive cardiomegaly, severe cardiac and respiratory complications and failure to thrive. Non-specific facial dysmorphism, bilateral cataracts, macroglossia, hydrocephalus, enlarged kidneys and skeletal muscle involvement have been reported in some cases.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/337919">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_354734"><div><strong>Lown-Ganong-Levine syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>354734</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1862387</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Lown-Ganong-Levine syndrome is an extremely rare conduction disorder characterized by a short PR interval (less than or equal to 120 ms) with normal QRS complex on electrocardiogram associated with the occurrence of episodes of atrial tachyarrythmias (e.g. atrial fibrillation, atrial tachycardia).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/354734">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_370220"><div><strong>Progressive familial heart block type IB</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>370220</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C1970298</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Progressive familial heart block can be divided into type I and type II, with type I being further divided into types IA and IB. These types differ in where in the heart signaling is interrupted and the genetic cause. In types IA and IB, the heart block originates in the bundle branch, and in type II, the heart block originates in the atrioventricular node. The different types of progressive familial heart block have similar signs and symptoms.\n\nMost cases of heart block are not genetic and are not considered progressive familial heart block. The most common cause of heart block is fibrosis of the heart, which occurs as a normal process of aging. Other causes of heart block can include the use of certain medications or an infection of the heart tissue.\n\nHeart block occurs when the electrical signaling is obstructed anywhere from the atria to the ventricles. In people with progressive familial heart block, the condition worsens over time: early in the disorder, the electrical signals are partially blocked, but the block eventually becomes complete, preventing any signals from passing through the heart. Partial heart block causes a slow or irregular heartbeat (bradycardia or arrhythmia, respectively), and can lead to the buildup of scar tissue (fibrosis) in the cells that carry electrical impulses. Fibrosis contributes to the development of complete heart block, resulting in uncoordinated electrical signaling between the atria and the ventricles and inefficient pumping of blood in the heart. Complete heart block can cause a sensation of fluttering or pounding in the chest (palpitations), shortness of breath, fainting (syncope), or sudden cardiac arrest and death.\n\nProgressive familial heart block is a genetic condition that alters the normal beating of the heart. A normal heartbeat is controlled by electrical signals that move through the heart in a highly coordinated way. These signals begin in a specialized cluster of cells called the sinoatrial node (the heart's natural pacemaker) located in the heart's upper chambers (the atria). From there, a group of cells called the atrioventricular node carries the electrical signals to another cluster of cells called the bundle of His. This bundle separates into multiple thin spindles called bundle branches, which carry electrical signals into the heart's lower chambers (the ventricles). Electrical impulses move from the sinoatrial node down to the bundle branches, stimulating a normal heartbeat in which the ventricles contract slightly later than the atria.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/370220">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1646555"><div><strong>Combined oxidative phosphorylation defect type 15</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1646555</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C4706313</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">A rare mitochondrial disease due to a defect in mitochondrial protein synthesis with onset in infancy or early childhood of muscular hypotonia, gait ataxia, mild bilateral pyramidal tract signs, developmental delay (affecting mostly speech and coordination) and subsequent intellectual disability. Short stature, obesity, microcephaly, strabismus, nystagmus, reduced visual acuity, lactic acidosis, and a brain neuropathology consistent with Leigh syndrome are also reported. Caused by homozygous or compound heterozygous mutation in the MTFMT gene on chromosome 15q22.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1646555">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_1823998"><div><strong>Neurodevelopmental disorder with microcephaly, cerebral atrophy, and visual impairment</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>1823998</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C5774225</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Neurodevelopmental disorder with microcephaly, cerebral atrophy, and visual impairment (NEDMVIC) is an autosomal recessive disorder characterized by global developmental delay, impaired intellectual development, facial dysmorphism, and microcephaly (Ziegler et al., 2022).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/1823998">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1646555" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Combined oxidative phosphorylation defect type 15</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_5340" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Glycogen storage disease, type II</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_331466" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Hypertrophic cardiomyopathy 6</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_337919" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Lethal congenital glycogen storage disease of heart</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_354734" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Lown-Ganong-Levine syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_1823998" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Neurodevelopmental disorder with microcephaly, cerebral atrophy, and visual impairment</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_370220" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Progressive familial heart block type IB</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_12162" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Wolff-Parkinson-White pattern</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/35094613">High-intensity focused ultrasound treatment for symptomatic uterine fibroids: a systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Yan L,
|
||
Huang H,
|
||
Lin J,
|
||
Yu R</span><br />
|
||
<span class="medgenPMjournal">Int J Hyperthermia</span>
|
||
2022;39(1):230-238.
|
||
doi: 10.1080/02656736.2022.2029956.
|
||
<span class="bold">PMID: </span><a href="/pubmed/35094613" target="_blank">35094613</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/26686022">Subcutaneous administration of methotrexate at high doses makes a better performance in the treatment of rheumatoid arthritis compared with oral administration of methotrexate: A systematic review and meta-analysis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Li D,
|
||
Yang Z,
|
||
Kang P,
|
||
Xie X</span><br />
|
||
<span class="medgenPMjournal">Semin Arthritis Rheum</span>
|
||
2016 Jun;45(6):656-62.
|
||
Epub 2015 Dec 1
|
||
doi: 10.1016/j.semarthrit.2015.11.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26686022" target="_blank">26686022</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/24287008">New electrocardiographic criteria to differentiate acute pericarditis and myocardial infarction.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rossello X,
|
||
Wiegerinck RF,
|
||
Alguersuari J,
|
||
Bardají A,
|
||
Worner F,
|
||
Sutil M,
|
||
Ferrero A,
|
||
Cinca J</span><br />
|
||
<span class="medgenPMjournal">Am J Med</span>
|
||
2014 Mar;127(3):233-9.
|
||
Epub 2013 Nov 25
|
||
doi: 10.1016/j.amjmed.2013.11.006.
|
||
<span class="bold">PMID: </span><a href="/pubmed/24287008" target="_blank">24287008</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(shortened%20pr%20interval)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (9)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/28109825">Trends in coronary risk factors and electrocardiogram findings from 1977 to 2009 with 10-year mortality in Japanese elderly males - The Tanushimaru Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nakamura S,
|
||
Adachi H,
|
||
Enomoto M,
|
||
Fukami A,
|
||
Kumagai E,
|
||
Nohara Y,
|
||
Kono S,
|
||
Nakao E,
|
||
Sakaue A,
|
||
Tsuru T,
|
||
Morikawa N,
|
||
Fukumoto Y</span><br />
|
||
<span class="medgenPMjournal">J Cardiol</span>
|
||
2017 Oct;70(4):353-358.
|
||
Epub 2017 Jan 18
|
||
doi: 10.1016/j.jjcc.2016.12.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28109825" target="_blank">28109825</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23768165">Resting ECG findings in elite football players.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bohm P,
|
||
Ditzel R,
|
||
Ditzel H,
|
||
Urhausen A,
|
||
Meyer T</span><br />
|
||
<span class="medgenPMjournal">J Sports Sci</span>
|
||
2013;31(13):1475-80.
|
||
Epub 2013 Jun 17
|
||
doi: 10.1080/02640414.2013.796067.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23768165" target="_blank">23768165</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17223994">Effects of testosterone and nandrolone on cardiac function: a randomized, placebo-controlled study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chung T,
|
||
Kelleher S,
|
||
Liu PY,
|
||
Conway AJ,
|
||
Kritharides L,
|
||
Handelsman DJ</span><br />
|
||
<span class="medgenPMjournal">Clin Endocrinol (Oxf)</span>
|
||
2007 Feb;66(2):235-45.
|
||
doi: 10.1111/j.1365-2265.2006.02715.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17223994" target="_blank">17223994</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16702879">Electrocardiographic response to enzyme replacement therapy for Pompe disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ansong AK,
|
||
Li JS,
|
||
Nozik-Grayck E,
|
||
Ing R,
|
||
Kravitz RM,
|
||
Idriss SF,
|
||
Kanter RJ,
|
||
Rice H,
|
||
Chen YT,
|
||
Kishnani PS</span><br />
|
||
<span class="medgenPMjournal">Genet Med</span>
|
||
2006 May;8(5):297-301.
|
||
doi: 10.1097/01.gim.0000195896.04069.5f.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16702879" target="_blank">16702879</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Shortened%20PR%20interval%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/26989114">Atypical patterns of cardiac involvement in Fabry disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Coughlan JJ,
|
||
Elkholy K,
|
||
O'Brien J,
|
||
Kiernan T</span><br />
|
||
<span class="medgenPMjournal">BMJ Case Rep</span>
|
||
2016 Mar 17;2016
|
||
doi: 10.1136/bcr-2015-213819.
|
||
<span class="bold">PMID: </span><a href="/pubmed/26989114" target="_blank">26989114</a><a href="/pmc/articles/PMC4800201" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23768165">Resting ECG findings in elite football players.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Bohm P,
|
||
Ditzel R,
|
||
Ditzel H,
|
||
Urhausen A,
|
||
Meyer T</span><br />
|
||
<span class="medgenPMjournal">J Sports Sci</span>
|
||
2013;31(13):1475-80.
|
||
Epub 2013 Jun 17
|
||
doi: 10.1080/02640414.2013.796067.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23768165" target="_blank">23768165</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/23224264">Second-degree atrioventricular block revisited.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Barold SS,
|
||
Herweg B</span><br />
|
||
<span class="medgenPMjournal">Herzschrittmacherther Elektrophysiol</span>
|
||
2012 Dec;23(4):296-304.
|
||
Epub 2012 Dec 7
|
||
doi: 10.1007/s00399-012-0240-8.
|
||
<span class="bold">PMID: </span><a href="/pubmed/23224264" target="_blank">23224264</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/11155413">Second-degree atrioventricular block: a reappraisal.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Barold SS,
|
||
Hayes DL</span><br />
|
||
<span class="medgenPMjournal">Mayo Clin Proc</span>
|
||
2001 Jan;76(1):44-57.
|
||
doi: 10.4065/76.1.44.
|
||
<span class="bold">PMID: </span><a href="/pubmed/11155413" target="_blank">11155413</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/10409546">A new ECG sign of an accessory pathway in sinus rhythm: pseudo partial right bundle branch block.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Lau EW,
|
||
Ng GA,
|
||
Griffith MJ</span><br />
|
||
<span class="medgenPMjournal">Heart</span>
|
||
1999 Aug;82(2):244-5.
|
||
doi: 10.1136/hrt.82.2.244.
|
||
<span class="bold">PMID: </span><a href="/pubmed/10409546" target="_blank">10409546</a><a href="/pmc/articles/PMC1729155" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Shortened%20PR%20interval%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (7)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/28109825">Trends in coronary risk factors and electrocardiogram findings from 1977 to 2009 with 10-year mortality in Japanese elderly males - The Tanushimaru Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nakamura S,
|
||
Adachi H,
|
||
Enomoto M,
|
||
Fukami A,
|
||
Kumagai E,
|
||
Nohara Y,
|
||
Kono S,
|
||
Nakao E,
|
||
Sakaue A,
|
||
Tsuru T,
|
||
Morikawa N,
|
||
Fukumoto Y</span><br />
|
||
<span class="medgenPMjournal">J Cardiol</span>
|
||
2017 Oct;70(4):353-358.
|
||
Epub 2017 Jan 18
|
||
doi: 10.1016/j.jjcc.2016.12.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28109825" target="_blank">28109825</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17223994">Effects of testosterone and nandrolone on cardiac function: a randomized, placebo-controlled study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chung T,
|
||
Kelleher S,
|
||
Liu PY,
|
||
Conway AJ,
|
||
Kritharides L,
|
||
Handelsman DJ</span><br />
|
||
<span class="medgenPMjournal">Clin Endocrinol (Oxf)</span>
|
||
2007 Feb;66(2):235-45.
|
||
doi: 10.1111/j.1365-2265.2006.02715.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17223994" target="_blank">17223994</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16702879">Electrocardiographic response to enzyme replacement therapy for Pompe disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ansong AK,
|
||
Li JS,
|
||
Nozik-Grayck E,
|
||
Ing R,
|
||
Kravitz RM,
|
||
Idriss SF,
|
||
Kanter RJ,
|
||
Rice H,
|
||
Chen YT,
|
||
Kishnani PS</span><br />
|
||
<span class="medgenPMjournal">Genet Med</span>
|
||
2006 May;8(5):297-301.
|
||
doi: 10.1097/01.gim.0000195896.04069.5f.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16702879" target="_blank">16702879</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7361796">Phenytoin toxicity and blood levels after a large oral dose.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Evens RP,
|
||
Fraser DG,
|
||
Ludden TM,
|
||
Sutherland EW 3rd</span><br />
|
||
<span class="medgenPMjournal">Am J Hosp Pharm</span>
|
||
1980 Feb;37(2):232-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7361796" target="_blank">7361796</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Shortened%20PR%20interval%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/28109825">Trends in coronary risk factors and electrocardiogram findings from 1977 to 2009 with 10-year mortality in Japanese elderly males - The Tanushimaru Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nakamura S,
|
||
Adachi H,
|
||
Enomoto M,
|
||
Fukami A,
|
||
Kumagai E,
|
||
Nohara Y,
|
||
Kono S,
|
||
Nakao E,
|
||
Sakaue A,
|
||
Tsuru T,
|
||
Morikawa N,
|
||
Fukumoto Y</span><br />
|
||
<span class="medgenPMjournal">J Cardiol</span>
|
||
2017 Oct;70(4):353-358.
|
||
Epub 2017 Jan 18
|
||
doi: 10.1016/j.jjcc.2016.12.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28109825" target="_blank">28109825</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Shortened%20PR%20interval%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/28109825">Trends in coronary risk factors and electrocardiogram findings from 1977 to 2009 with 10-year mortality in Japanese elderly males - The Tanushimaru Study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nakamura S,
|
||
Adachi H,
|
||
Enomoto M,
|
||
Fukami A,
|
||
Kumagai E,
|
||
Nohara Y,
|
||
Kono S,
|
||
Nakao E,
|
||
Sakaue A,
|
||
Tsuru T,
|
||
Morikawa N,
|
||
Fukumoto Y</span><br />
|
||
<span class="medgenPMjournal">J Cardiol</span>
|
||
2017 Oct;70(4):353-358.
|
||
Epub 2017 Jan 18
|
||
doi: 10.1016/j.jjcc.2016.12.004.
|
||
<span class="bold">PMID: </span><a href="/pubmed/28109825" target="_blank">28109825</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/17223994">Effects of testosterone and nandrolone on cardiac function: a randomized, placebo-controlled study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Chung T,
|
||
Kelleher S,
|
||
Liu PY,
|
||
Conway AJ,
|
||
Kritharides L,
|
||
Handelsman DJ</span><br />
|
||
<span class="medgenPMjournal">Clin Endocrinol (Oxf)</span>
|
||
2007 Feb;66(2):235-45.
|
||
doi: 10.1111/j.1365-2265.2006.02715.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/17223994" target="_blank">17223994</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/16702879">Electrocardiographic response to enzyme replacement therapy for Pompe disease.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Ansong AK,
|
||
Li JS,
|
||
Nozik-Grayck E,
|
||
Ing R,
|
||
Kravitz RM,
|
||
Idriss SF,
|
||
Kanter RJ,
|
||
Rice H,
|
||
Chen YT,
|
||
Kishnani PS</span><br />
|
||
<span class="medgenPMjournal">Genet Med</span>
|
||
2006 May;8(5):297-301.
|
||
doi: 10.1097/01.gim.0000195896.04069.5f.
|
||
<span class="bold">PMID: </span><a href="/pubmed/16702879" target="_blank">16702879</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7361796">Phenytoin toxicity and blood levels after a large oral dose.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Evens RP,
|
||
Fraser DG,
|
||
Ludden TM,
|
||
Sutherland EW 3rd</span><br />
|
||
<span class="medgenPMjournal">Am J Hosp Pharm</span>
|
||
1980 Feb;37(2):232-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7361796" target="_blank">7361796</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Shortened%20PR%20interval%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (4)</a></div></div>
|
||
</div>
|
||
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|
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|
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|
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|
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|
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<div class="supplemental col three_col last">
|
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<h2 class="offscreen_noflow">Supplemental Content</h2>
|
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|
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|
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|
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Table_of_contents">Table of contents</h1><a sid="113" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln"><ul><li><a href="https://clinicaltrials.gov/search?cond=Shortened%20PR%20interval" target="_blank">ClinicalTrials.gov</a></li></ul></div>
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<div class="portlet_content ln"><ul class="a_poppers"><li><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(shortened%20pr%20interval)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">PubMed</a><div class="help-popup">See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div></li></ul></div>
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