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<!--
|
||
UID=105441
|
||
ConceptID=C0520463
|
||
-->
|
||
<!--imgCountBooks = 0--><h1 class="medgenTitle"><div class="MedGenTitleText">Chronic active hepatitis</div></h1><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>105441</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0520463</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div><table class="medgenTable"><tbody><tr><td>Synonyms:</td>
|
||
<td>Chronic Active Hepatitis; Hepatitis, Chronic Active</td></tr>
|
||
<tr><td><span class="bold">SNOMED CT: </span></td>
|
||
<td>Chronic active hepatitis (197284004); CAH - Chronic active hepatitis (197284004); CAH - Chronic aggressive hepatitis (197284004)</td></tr>
|
||
<tr><td colspan="2" class="small"> </td></tr><tr><td>HPO:</td>
|
||
<td><a target="_blank" title="Human Phenotype Ontology" href="https://hpo.jax.org/app/browse/term/HP:0200120">HP:0200120</a></td></tr>
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<div class="portlet mgSection" id="ID_100">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Definition">Definition</h1><a sid="100" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">Chronic hepatitis associated with recurrent clinical exacerbations, extrahepatic manifestations, and progression to cirrhosis. [from <a title="Human Phenotype Ontology" href="http://www.human-phenotype-ontology.org" class="defSource" target="_blank">HPO</a>]</div>
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<div class="portlet mgSection" id="ID_118">
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<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Term_Hierarchy">Term Hierarchy</h1><a sid="118" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
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<div class="portlet_content ln HierarchyGTR"><div class="jig-ncbitabs"><ul><li><a href="#tabGTR">GTR</a></li><li><a href="#tabMGEN">MeSH</a></li></ul><div id="tabGTR"><div class="search_result"><div class="rprts"><div class="chiclet_legend"><span class="chiclet_list" style="position:static;"><span title="Clinical test" class="chiclet Ccolor round">C</span><span>Clinical test, </span><span title="Research test" class="chiclet Rcolor round">R</span><span>Research test, </span><span title="OMIM" class="chiclet Ocolor ">O</span><span>OMIM, </span><span title="GeneReview" class="chiclet Gcolor">G</span><span><em>GeneReviews</em>, </span><span title="ClinVar" class="chiclet Vcolor">V</span><span>ClinVar </span></span></div><div id="hierarchy" class="margin_t1"><div class="ds_tree"><ul><li class="matched_ds"><span class="chiclet_list"><span class="chiclet unavailable round" title="Clinical test">C</span><span class="chiclet unavailable round" title="Research Tests">R</span><span class="chiclet unavailable" title="OMIM">O</span><span class="chiclet unavailable" title="GeneReviews">G</span><span class="chiclet unavailable" title="ClinVar">V</span></span><span class="TLline">Chronic active hepatitis</span></li></ul></div></div></div></div></div><div id="tabMGEN"><div class="ds_tree"><ul><li><span class="TLline"><a href="/medgen/21047" ref="tree=MeSH" title="MedGen record for Pathological Conditions, Signs and Symptoms">Pathological Conditions, Signs and Symptoms</a></span><ul><li><span class="TLline"><a href="/medgen/18325" ref="tree=MeSH" title="MedGen record for Pathological process">Pathological process</a></span><ul><li><span class="TLline"><a href="/medgen/199876" ref="tree=MeSH" title="MedGen record for Disease Attributes">Disease Attributes</a></span><ul><li><span class="TLline"><a href="/medgen/3453" ref="tree=MeSH" title="MedGen record for Chronic disease">Chronic disease</a></span><ul><li><span class="TLline"><a href="/medgen/9223" ref="tree=MeSH" title="MedGen record for Chronic hepatitis">Chronic hepatitis</a></span><ul><li><span class="matched_ds">Chronic active hepatitis</span></li></ul></li></ul></li></ul></li></ul></li></ul></li></ul></div></div></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_112">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Conditions_with_this_feature">Conditions with this feature</h1><a sid="112" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln clinfeat">
|
||
<div class="divPopper rprt" id="rdis_39125"><div><strong>Polyglandular autoimmune syndrome, type 1</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>39125</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C0085859</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Autoimmune polyglandular syndrome type I (APS1) is characterized by the presence of 2 of 3 major clinical symptoms: Addison disease, and/or hypoparathyroidism, and/or chronic mucocutaneous candidiasis (Neufeld et al., 1981). However, variable APS1 phenotypes have been observed, even among sibs. In addition, some patients may exhibit apparent isolated hypoparathyroidism, an early manifestation of APS1 with peak incidence at around age 5 years; over long-term follow-up, the development of additional features of APS1 may be observed (Cranston et al., 2022).</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/39125">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_78675"><div><strong>Alstrom syndrome</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>78675</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information."><span class="highlight" style="background-color:">C0268425</span></a></dd><dt><span class="dotprefix"> •</span></dt><dd>Disease or Syndrome</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Alström syndrome is characterized by cone-rod dystrophy, obesity, progressive bilateral sensorineural hearing impairment, acute infantile-onset cardiomyopathy and/or adolescent- or adult-onset restrictive cardiomyopathy, insulin resistance / type 2 diabetes mellitus (T2DM), nonalcoholic fatty liver disease (NAFLD), and chronic progressive kidney disease. Cone-rod dystrophy presents as progressive visual impairment, photophobia, and nystagmus usually starting between birth and age 15 months. Many individuals lose all perception of light by the end of the second decade, but a minority retain the ability to read large print into the third decade. Children usually have normal birth weight but develop truncal obesity during their first year. Sensorineural hearing loss presents in the first decade in as many as 70% of individuals and may progress to the severe or moderately severe range (40-70 db) by the end of the first to second decade. Insulin resistance is typically accompanied by the skin changes of acanthosis nigricans, and proceeds to T2DM in the majority by the third decade. Nearly all demonstrate hypertriglyceridemia. Other findings can include endocrine abnormalities (hypothyroidism, hypogonadotropic hypogonadism in males, and hyperandrogenism in females), urologic dysfunction / detrusor instability, progressive decrease in renal function, and hepatic disease (ranging from elevated transaminases to steatohepatitis/NAFLD). Approximately 20% of affected individuals have delay in early developmental milestones, most commonly in gross and fine motor skills. About 30% have a learning disability. Cognitive impairment (IQ <70) is very rare. Wide clinical variability is observed among affected individuals, even within the same family.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/78675">Condition Record</a></div></div>
|
||
<div class="divPopper rprt" id="rdis_482271"><div><strong>Complement component 4b deficiency</strong><div class="aux"><div class="resc"><dl class="rprtid"><dt>MedGen UID: </dt><dd>482271</dd><dt><span class="dotprefix"> •</span>Concept ID: </dt><dd><a href="/medgen/docs/help/#sources" target="_blank" title="Concept Unique Identifier from NLM's Unified Medical Language system (UMLS) Click for more information.">C3280641</a></dd><dt><span class="dotprefix"> •</span></dt><dd>Finding</dd></dl></div></div></div>
|
||
<div class="spaceAbove">Concentration of the complement component C4b in the blood circulation below the lower limit of normal.</div>
|
||
<div class="spaceAbove nowrap">See: <a href="/medgen/482271">Condition Record</a></div></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_78675" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Alstrom syndrome</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_482271" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Complement component 4b deficiency</a></div>
|
||
<div class="hangingIndent"><a title="click for more information" class="jig-ncbipopper" href="#rdis_39125" data-jigconfig="hasArrow: true, openEvent: 'click', closeEvent: 'mouseout', openAnimation: 'fadeIn', closeAnimation: 'fadeOut', triggerPosition: 'center right', destPosition: 'center left', arrowDirection: 'left'">Polyglandular autoimmune syndrome, type 1</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_105">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Professional_guidelines">Professional guidelines</h1><a sid="105" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">PubMed<a class="help jig-ncbi-popper" data-jig="ncbipopper" href="#guidelinesHelpPM"><img class="pulldown" src="//static.pubmed.gov/portal/portal3rc.fcgi/4223267/img/4204968" /></a></h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/440338">Transfer factor for the treatment of chronic active hepatitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Pizza G,
|
||
Viza D,
|
||
Roda A,
|
||
Aldini R,
|
||
Roda E,
|
||
Barbara L</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
1979 Jun 7;300(23):1332.
|
||
doi: 10.1056/NEJM197906073002311.
|
||
<span class="bold">PMID: </span><a href="/pubmed/440338" target="_blank">440338</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/5130351">Chronic active hepatitis. Definition, diagnosis and management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sherlock S</span><br />
|
||
<span class="medgenPMjournal">Postgrad Med</span>
|
||
1971 Nov;50(5):206-11.
|
||
doi: 10.1080/00325481.1971.11697676.
|
||
<span class="bold">PMID: </span><a href="/pubmed/5130351" target="_blank">5130351</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/6080446">The treatment of active chronic hepatitis with 6-mercaptopurine and azathioprine.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mistilis SP,
|
||
Blackburn CR</span><br />
|
||
<span class="medgenPMjournal">Australas Ann Med</span>
|
||
1967 Nov;16(4):305-11.
|
||
doi: 10.1111/imj.1967.16.4.305.
|
||
<span class="bold">PMID: </span><a href="/pubmed/6080446" target="_blank">6080446</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=(%22chronic%20active%20hepatitis%22%5Btiab%3A~0%5D)%20AND%20(%22english%20and%20humans%22%5BFilter%5D)%20AND%20(%20(%22practice%20guideline%22%5BFilter%5D)%20OR%20(practice*%5Btitl%5D%20AND%20(guideline%5Btitl%5D%20OR%20parameter%5Btitl%5D%20OR%20resource%5Btitl%5D%20OR%20bulletin%5Btitl%5D%20OR%20best%5Btitl%5D))%20OR%20(genetic*%5Btitl%5D%20AND%20(evaluation%5Btitl%5D%20OR%20counseling%5Btitl%5D%20OR%20screening%5Btitl%5D%20OR%20test*%5Btitl%5D))%20OR%20(clinical%5Btitl%5D%20AND%20((expert%5Btitl%5D%20AND%20consensus%5Btitl%5D)%20OR%20utility%5Btitl%5D%20OR%20guideline*%5Btitl%5D))%20OR%20(management%5Btitl%5D%20AND%20(clinical%5Btitl%5D%20OR%20diagnos*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20pain%5Btitl%5D%20OR%20surveillance%5Btitl%5D%20OR%20emergency%5Btitl%5D%20OR%20guideline*%5Btitl%5D%20OR%20therap*))%20OR%20(treatment%5Btitl%5D%20AND%20((evaluation%5Btitl%5D%20AND%20diagnosis%5Btitl%5D)%20OR%20(assessment%5Btitl%5D%20AND%20prevention%5Btitl%5D)%20OR%20therap*))%20OR%20(Diagnos*%5Btitl%5D%20AND%20(prenatal%5Btitl%5D%20OR%20treatment%5Btitl%5D%20OR%20follow-up%5Btitl%5D%20OR%20statement%5Btitl%5D%20OR%20criteria%5Btitl%5D%20OR%20newborn%5Btitl%5D%20OR%20differential%5Btitl%5D%20OR%20neonatal%5Btitl%5D%20OR%20neonate%5Btitl%5D))%20OR%20(guideline*%5Btitl%5D%20AND%20(pharmacogenetic*%5Btitl%5D%20OR%20recommendation%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20evidence-based%5Btitl%5D%20OR%20consensus%5Btitl%5D%20OR%20(technical%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20(molecular%5Btitl%5D%20AND%20testing%5Btitl%5D)))%20OR%20(risk%5Btitl%5D%20AND%20assessment%5Btitl%5D)%20OR%20(recommendation*%5Btitl%5D%20AND%20(statement%5Btitl%5D%20OR%20Evidence-based%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(care%20AND%20((Patient%5Btitl%5D%20AND%20standard*%5Btitl%5D)%20OR%20primary%5Btitl%5D%20OR%20psychosocial%5Btitl%5D))%20OR%20(Health%5Btitl%5D%20AND%20supervision%5Btitl%5D)%20OR%20(statement%5Btitl%5D%20AND%20(policy%5Btitl%5D%20OR%20position%5Btitl%5D%20OR%20Consensus%5Btitl%5D))%20OR%20(pharmacogenetics%5Btitl%5D%20AND%20(Dosing%5Btitl%5D%20OR%20therap*%5Btitl%5D%20OR%20genotype*%5Btitl%5D%20OR%20drug*%5Btitl%5D))%20OR%20(Chemotherapy%5Btitl%5D%20AND%20decision*%5Btitl%5D)%20OR%20(screening%5Btitl%5D%20AND%20(newborn%5Btitl%5D%20OR%20neonat*%5Btitl%5D%20OR%20detection%5Btitl%5D%20OR%20diagnos*%5Btitl%5D))%20OR%20(criteria%5Btitl%5D%20OR%20genotype*%5Btitl%5D)%20)%20NOT%20(%22Case%20reports%22%5BPublication%20type%5D%20OR%20%22clinical%20study%22%5BPublication%20Type%5D%20OR%20%22randomized%20controlled%20trial%22%5BPublication%20Type%5D)" title="PubMed search">See all (164)</a></div></div>
|
||
</div>
|
||
<div class="display-none help-popup" id="guidelinesHelpPM">These guidelines are articles in PubMed that match specific search criteria developed by MedGen to capture the most relevant practice guidelines. This list may not be comprehensive and may include broader topics as well. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div><div class="display-none help-popup" id="guidelinesHelpCurated">These guidelines are manually curated by the MedGen team
|
||
to supplement articles available in PubMed. See the <a href="/medgen/docs/faq/" title="Frequently asked questions" target="_blank">FAQ</a> for details.</div>
|
||
<div class="portlet mgSection" id="ID_103">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_clinical_studies">Recent clinical studies</h1><a sid="103" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln"><h3 class="subhead">Etiology</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/6183875">Chronic active hepatitis and lichen planus.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Rebora A,
|
||
Rongioletti F,
|
||
Canepa A</span><br />
|
||
<span class="medgenPMjournal">Acta Derm Venereol</span>
|
||
1982;62(4):351-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/6183875" target="_blank">6183875</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7350855">Nitrofurantoin and chronic active hepatitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Tolman KG</span><br />
|
||
<span class="medgenPMjournal">Ann Intern Med</span>
|
||
1980 Jan;92(1):119-20.
|
||
doi: 10.7326/0003-4819-92-1-119.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7350855" target="_blank">7350855</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/328194">Autoimmunity in chronic active hepatitis and diabetes mellitus.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Galbraith RM,
|
||
Fudenberg HH</span><br />
|
||
<span class="medgenPMjournal">Clin Immunol Immunopathol</span>
|
||
1977 Jul;8(1):116-49.
|
||
doi: 10.1016/0090-1229(77)90099-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/328194" target="_blank">328194</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/788587">Corticosteroid therapy for chronic active hepatitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Berk PD,
|
||
Jones EA,
|
||
Plotz PH,
|
||
Seeff LB,
|
||
Wright EC</span><br />
|
||
<span class="medgenPMjournal">Ann Intern Med</span>
|
||
1976 Oct;85(4):523-5.
|
||
doi: 10.7326/0003-4819-85-4-523.
|
||
<span class="bold">PMID: </span><a href="/pubmed/788587" target="_blank">788587</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/4338952">Experimental chronic active hepatitis in rabbits following immunization with human liver proteins.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Büschenfelde KH,
|
||
Kössling FK,
|
||
Miescher PA</span><br />
|
||
<span class="medgenPMjournal">Clin Exp Immunol</span>
|
||
1972 May;11(1):99-108.
|
||
<span class="bold">PMID: </span><a href="/pubmed/4338952" target="_blank">4338952</a><a href="/pmc/articles/PMC1553689" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Chronic%20active%20hepatitis%22%20AND%20Etiology%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1212)</a></div><h3 class="subhead">Diagnosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/1925643">The natural course and heterogeneity of autoimmune-type chronic active hepatitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Johnson PJ,
|
||
McFarlane IG,
|
||
Eddleston AL</span><br />
|
||
<span class="medgenPMjournal">Semin Liver Dis</span>
|
||
1991 Aug;11(3):187-96.
|
||
doi: 10.1055/s-2008-1040436.
|
||
<span class="bold">PMID: </span><a href="/pubmed/1925643" target="_blank">1925643</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/6203393">Chronic active hepatitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Kolts BE,
|
||
Spindel E</span><br />
|
||
<span class="medgenPMjournal">Am Fam Physician</span>
|
||
1984 Jun;29(6):228-43.
|
||
<span class="bold">PMID: </span><a href="/pubmed/6203393" target="_blank">6203393</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7051296">Drug-induced chronic liver disease, with emphasis on chronic active hepatitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Seeff LB</span><br />
|
||
<span class="medgenPMjournal">Semin Liver Dis</span>
|
||
1981 May;1(2):104-15.
|
||
doi: 10.1055/s-2008-1040723.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7051296" target="_blank">7051296</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/1010632">Chronic active hepatitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Krishnamurthy L,
|
||
Singh DS,
|
||
Tandon HD,
|
||
Tandon BN</span><br />
|
||
<span class="medgenPMjournal">Indian J Med Res</span>
|
||
1976 Sep;64(9):1376-84.
|
||
<span class="bold">PMID: </span><a href="/pubmed/1010632" target="_blank">1010632</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/5130351">Chronic active hepatitis. Definition, diagnosis and management.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Sherlock S</span><br />
|
||
<span class="medgenPMjournal">Postgrad Med</span>
|
||
1971 Nov;50(5):206-11.
|
||
doi: 10.1080/00325481.1971.11697676.
|
||
<span class="bold">PMID: </span><a href="/pubmed/5130351" target="_blank">5130351</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Chronic%20active%20hepatitis%22%20AND%20Diagnosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (955)</a></div><h3 class="subhead">Therapy</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/1720439">Combination therapy with ARA-AMP and interferon of chronic active hepatitis B. Interim analysis of an ongoing study.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Trépo C,
|
||
Rougier P,
|
||
Bizollon T,
|
||
Poupon R,
|
||
Zarski JP,
|
||
Quinton A,
|
||
Miguet JP,
|
||
Causse X,
|
||
Chossegros P,
|
||
Chevallier M</span><br />
|
||
<span class="medgenPMjournal">J Hepatol</span>
|
||
1991;13 Suppl 1:S3.
|
||
doi: 10.1016/0168-8278(91)91711-o.
|
||
<span class="bold">PMID: </span><a href="/pubmed/1720439" target="_blank">1720439</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/6893265">Propylthiouracil-induced hepatic damage.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Weiss M,
|
||
Hassin D,
|
||
Bank H</span><br />
|
||
<span class="medgenPMjournal">Arch Intern Med</span>
|
||
1980 Sep;140(9):1184-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/6893265" target="_blank">6893265</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/1010632">Chronic active hepatitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Krishnamurthy L,
|
||
Singh DS,
|
||
Tandon HD,
|
||
Tandon BN</span><br />
|
||
<span class="medgenPMjournal">Indian J Med Res</span>
|
||
1976 Sep;64(9):1376-84.
|
||
<span class="bold">PMID: </span><a href="/pubmed/1010632" target="_blank">1010632</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/4753638">Editorial: Chronic active hepatitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Javitt NB</span><br />
|
||
<span class="medgenPMjournal">Am J Med</span>
|
||
1973 Dec;55(6):733-5.
|
||
doi: 10.1016/0002-9343(73)90253-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/4753638" target="_blank">4753638</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/5113720">Oxyphenisatin and chronic active hepatitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Mallory A,
|
||
Frank BW,
|
||
Kern F Jr</span><br />
|
||
<span class="medgenPMjournal">N Engl J Med</span>
|
||
1971 Nov 25;285(22):1266.
|
||
doi: 10.1056/NEJM197111252852220.
|
||
<span class="bold">PMID: </span><a href="/pubmed/5113720" target="_blank">5113720</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Chronic%20active%20hepatitis%22%20AND%20Therapy%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (998)</a></div><h3 class="subhead">Prognosis</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/12848952">The epidemiology of autoimmune diseases.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Cooper GS,
|
||
Stroehla BC</span><br />
|
||
<span class="medgenPMjournal">Autoimmun Rev</span>
|
||
2003 May;2(3):119-25.
|
||
doi: 10.1016/s1568-9972(03)00006-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/12848952" target="_blank">12848952</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/1925643">The natural course and heterogeneity of autoimmune-type chronic active hepatitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Johnson PJ,
|
||
McFarlane IG,
|
||
Eddleston AL</span><br />
|
||
<span class="medgenPMjournal">Semin Liver Dis</span>
|
||
1991 Aug;11(3):187-96.
|
||
doi: 10.1055/s-2008-1040436.
|
||
<span class="bold">PMID: </span><a href="/pubmed/1925643" target="_blank">1925643</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/328194">Autoimmunity in chronic active hepatitis and diabetes mellitus.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Galbraith RM,
|
||
Fudenberg HH</span><br />
|
||
<span class="medgenPMjournal">Clin Immunol Immunopathol</span>
|
||
1977 Jul;8(1):116-49.
|
||
doi: 10.1016/0090-1229(77)90099-x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/328194" target="_blank">328194</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/4753638">Editorial: Chronic active hepatitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Javitt NB</span><br />
|
||
<span class="medgenPMjournal">Am J Med</span>
|
||
1973 Dec;55(6):733-5.
|
||
doi: 10.1016/0002-9343(73)90253-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/4753638" target="_blank">4753638</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/5090106">Chronic active hepatitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Nuzum CT,
|
||
Phillips BA Jr</span><br />
|
||
<span class="medgenPMjournal">J Ky Med Assoc</span>
|
||
1971 Jun;69(6):440-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/5090106" target="_blank">5090106</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Chronic%20active%20hepatitis%22%20AND%20Prognosis%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (729)</a></div><h3 class="subhead">Clinical prediction guides</h3>
|
||
<div class="nl"><a target="_blank" href="/pubmed/3512925">Liver transplantation at the Mayo Clinic.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Krom RA</span><br />
|
||
<span class="medgenPMjournal">Mayo Clin Proc</span>
|
||
1986 Apr;61(4):278-82.
|
||
doi: 10.1016/s0025-6196(12)61930-2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/3512925" target="_blank">3512925</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/6873737">Effect of polyunsaturated phosphatidylcholine on immune mediated hepatocyte damage.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Neuberger J,
|
||
Hegarty JE,
|
||
Eddleston AL,
|
||
Williams R</span><br />
|
||
<span class="medgenPMjournal">Gut</span>
|
||
1983 Aug;24(8):751-5.
|
||
doi: 10.1136/gut.24.8.751.
|
||
<span class="bold">PMID: </span><a href="/pubmed/6873737" target="_blank">6873737</a><a href="/pmc/articles/PMC1420227" target="_blank" class="PubMedFree">Free PMC Article</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/7003492">Immunologic observations in chronic active hepatitis: a disease of different etiologies.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Paronetto F,
|
||
Sagnelli E</span><br />
|
||
<span class="medgenPMjournal">Pathobiol Annu</span>
|
||
1980;10:157-81.
|
||
<span class="bold">PMID: </span><a href="/pubmed/7003492" target="_blank">7003492</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/6893265">Propylthiouracil-induced hepatic damage.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Weiss M,
|
||
Hassin D,
|
||
Bank H</span><br />
|
||
<span class="medgenPMjournal">Arch Intern Med</span>
|
||
1980 Sep;140(9):1184-5.
|
||
<span class="bold">PMID: </span><a href="/pubmed/6893265" target="_blank">6893265</a></div>
|
||
|
||
<div class="nl"><a target="_blank" href="/pubmed/85369">Increased frequency of HLA-DRW4 in chronic active hepatitis.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Williams RM,
|
||
Martin S,
|
||
Falchuk KR,
|
||
Trey C,
|
||
Dubey DP,
|
||
Cannady WG,
|
||
Fitzpatrick D,
|
||
Noreen H,
|
||
Dupont B,
|
||
Yunis EJ</span><br />
|
||
<span class="medgenPMjournal">Vox Sang</span>
|
||
1978;35(6):366-9.
|
||
doi: 10.1111/j.1423-0410.1978.tb02948.x.
|
||
<span class="bold">PMID: </span><a href="/pubmed/85369" target="_blank">85369</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Chronic%20active%20hepatitis%22%20AND%20Clinical%20prediction%20guides%2Fbroad%5Bfilter%5D%20%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (799)</a></div></div>
|
||
</div>
|
||
|
||
<div class="portlet mgSection" id="ID_104">
|
||
<div class="portlet_head mgSectionHead ui-widget-header"><h1 class="nl" id="Recent_systematic_reviews">Recent systematic reviews</h1><a sid="104" href="#" class="portlet_shutter" title="Show/hide content"></a></div>
|
||
<div class="portlet_content ln">
|
||
<div class="nl"><a target="_blank" href="/pubmed/14974011">Azathioprine as an oral corticosteroid sparing agent for asthma.</a></div>
|
||
<div class="portlet_content ln"><span class="medgenPMauthor">Dean T,
|
||
Dewey A,
|
||
Bara A,
|
||
Lasserson TJ,
|
||
Walters EH</span><br />
|
||
<span class="medgenPMjournal">Cochrane Database Syst Rev</span>
|
||
2004;(1):CD003270.
|
||
doi: 10.1002/14651858.CD003270.pub2.
|
||
<span class="bold">PMID: </span><a href="/pubmed/14974011" target="_blank">14974011</a></div>
|
||
<div><a target="_blank" href="https://pubmed.ncbi.nlm.nih.gov/?term=%22Chronic%20active%20hepatitis%22%20AND%20systematic%5Bsb%5D%20AND%20%22english%20and%20humans%22%5Bfilter%5D%20NOT%20comment%5BPTYP%5D%20NOT%20letter%5BPTYP%5D" title="PubMed search">See all (1)</a></div></div>
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