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<div class="search"><div class="search_form"><label for="database" class="offscreen_noflow">Search database</label><select id="database"><optgroup label="Recent"><option value="medgen">MedGen</option><option value="books">Books</option><option value="pubmed">PubMed</option><option value="clinvar" class="last">ClinVar</option></optgroup><optgroup label="All"><option value="gquery">All Databases</option><option value="assembly" data-ac_dict="assembly">Assembly</option><option value="biocollections">Biocollections</option><option value="bioproject">BioProject</option><option value="biosample">BioSample</option><option value="books">Books</option><option value="clinvar">ClinVar</option><option value="cdd">Conserved Domains</option><option value="gap">dbGaP</option><option value="dbvar">dbVar</option><option value="gene" selected="selected" data-ac_dict="gene">Gene</option><option value="genome" data-ac_dict="genome">Genome</option><option value="gds">GEO DataSets</option><option value="geoprofiles">GEO Profiles</option><option value="gtr">GTR</option><option value="ipg">Identical Protein Groups</option><option value="medgen">MedGen</option><option value="mesh">MeSH</option><option value="nlmcatalog">NLM Catalog</option><option value="nuccore" data-ac_dict="nuccore">Nucleotide</option><option value="omim">OMIM</option><option value="pmc">PMC</option><option value="protein" data-ac_dict="protein">Protein</option><option value="proteinclusters">Protein Clusters</option><option value="protfam">Protein Family Models</option><option value="pcassay">PubChem BioAssay</option><option value="pccompound">PubChem Compound</option><option value="pcsubstance">PubChem Substance</option><option value="pubmed">PubMed</option><option value="snp">SNP</option><option value="sra">SRA</option><option value="structure">Structure</option><option value="taxonomy">Taxonomy</option><option value="toolkit">ToolKit</option><option value="toolkitall">ToolKitAll</option><option value="toolkitbookgh">ToolKitBookgh</option></optgroup></select><div class="nowrap"><label for="term" class="offscreen_noflow" accesskey="/">Search term</label><div class="nowrap"><input type="text" name="term" id="term" title="Search Gene. Use up and down arrows to choose an item from the autocomplete." value="" class="jig-ncbiclearbutton jig-ncbiautocomplete" data-jigconfig="dictionary:'gene',disableUrl:'NcbiSearchBarAutoComplCtrl'" autocomplete="off" data-sbconfig="ds:'no',pjs:'yes',afs:'yes'" /></div><button id="search" type="submit" class="button_search nowrap" cmd="go">Search</button></div></div><ul class="searchlinks inline_list"><set></set><li><a href="/gene/advanced">Advanced</a></li><li class="help"><a id="help" class="jig-ncbihelpwindow" target="ncbihelp" name="help" href="/books/NBK3841/">Help</a></li></ul></div>
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<div class="facet_cont" data-db="gene" data-default_grps="fg_gene-sources,fg_categories,fg_sequence-content,fg_status" data-sd="db:'gene',op:'select',term:'',qk:'925',linkname:'',idsfromresult:'7046',extra:''"><ul class="facet" data-filter_id="gene-sources" id="_gene-sources"><li class="filter_grp "><div class="clearfix"><h3>Gene sources</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="genomic">Genomic</a></li></ul></li></ul><ul class="facet" data-filter_id="categories" id="_categories"><li class="filter_grp "><div class="clearfix"><h3>Categories</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="alt-splicing">Alternatively spliced</a></li><li class="fil_val"><a href="#" data-value_id="annotated-genes">Annotated genes</a></li><li class="fil_val"><a href="#" data-value_id="gene-type-protein-coding">Protein-coding</a></li></ul></li></ul><ul class="facet" data-filter_id="sequence-content" id="_sequence-content"><li class="filter_grp "><div class="clearfix"><h3>Sequence content</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="seq-ccds">CCDS</a></li><li class="fil_val"><a href="#" data-value_id="seq-ensembl">Ensembl</a></li><li class="fil_val"><a href="#" data-value_id="refseq">RefSeq</a></li><li class="fil_val"><a href="#" data-value_id="seq-refseqgene">RefSeqGene</a></li></ul></li></ul><ul class="facet" data-filter_id="status" id="_status"><li class="filter_grp "><div class="clearfix"><h3>Status</h3><a href="#" data-value_id="" class="clear clear_show">Clear</a></div><ul><li class="fil_val selected"><a href="#" data-value_id="current-only">Current</a><span class="fcount">(1)</span></li></ul></li></ul><div id="chr-location-facet-wrapper" data-bid="MCID_67d68c534f3d5e000db75ff4" data-hid="MCID_67d65d956cc2d93e6b179a3d" data-qky="925" class="disabled" style="display:none"><ul class="facet" data-filter_id="chromosomal-region" id="_chromosomal-region" data-of="yes"><li class="filter_grp of_grp"><div class="clearfix"><h3>Chromosome locations</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><a id="facet_ofchromosomal-region" href="#facet_of_divchromosomal-region" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'middle left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '375px'" data-value_id="fetch_more">more...</a><div id="facet_of_divchromosomal-region" style="display:none;" class="of_popup"><h4>Chromosome locations</h4><label for="organism-filter" style="width:100%;margin-bottom:.2em;" class="">Select an organism by typing or scrolling</label><input type="text" placeholder="Enter text to narrow down the list" id="organism-filter" style="width:98%;" autocomplete="off" /><br /><div id="chr-region-tax-list"><select id="of_chromosomal-region" size="9" class="chr-region-tax-list" style="width:100%;"></select></div><div id="chr-location-info-ctrl" data-disabled="disabled"><div class="chr-field"><label for="chr-name">Chromosome</label><br /><select id="chr-name" class="chr-field" disabled="disabled"></select></div><div class="chr-field"><label for="chr-from">From</label><br /><input type="text" name="chr-from" id="chr-from" disabled="disabled" class="chr-field" /></div><div class="chr-field"><label for="chr-to">To</label><br /><input type="text" name="chr-to" id="chr-to" disabled="disabled" class="chr-field" /></div></div><div class="actions clearfix"><button class="jig-ncbibutton of_add apply-chr" data-jigconfig="'color': 'ui-ncbibutton-blue'">Apply</button></div></div></ul></li></ul></div><ul class="facet facet_reset"><li><a href="#" data-value_id="reset">Clear all</a></li></ul><ul class="facet_tools"><li><a id="more_filter_groups_link" href="#more_filter_groups" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'top left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '180px'">
Show additional filters</a></li><div id="more_filter_groups" style="display:none;" class="facets_dialog"><button class="ui-ncbipopper-close-button ui-ncbipopper-close-button-generated ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-blue" generated="true" role="button" aria-disabled="false"><span class="ui-button-text">x</span></button><h4>Additional filters</h4><ul class="filter_groups_more facet"><li><input type="checkbox" id="fg_gene-sources" /><label for="fg_gene-sources">Gene sources</label></li><li><input type="checkbox" id="fg_categories" /><label for="fg_categories">Categories</label></li><li><input type="checkbox" id="fg_sequence-content" /><label for="fg_sequence-content">Sequence content</label></li><li><input type="checkbox" id="fg_status" /><label for="fg_status">Status</label></li><li><input type="checkbox" id="fg_chromosomal-region" /><label for="fg_chromosomal-region">Chromosome locations</label></li><li><input id="fg_field_search" type="checkbox" /><label for="fg_field_search">Search fields</label></li></ul><div class="actions clearfix"><button class="filter_groups_more_apply jig-ncbibutton primary-action" id="filter_groups_apply" data-jigconfig="'color': 'ui-ncbibutton-blue'">Show</button></div></div></ul><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetsUrlFrag" sid="1" type="hidden" value="filters=current-only" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetSubmitted" sid="1" type="hidden" value="false" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.BMFacets" sid="1" type="hidden" value="" /></div>
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<h1 class="title" id="gene-name"><span class="gn" style="padding-right:.5em;">TGFBR1</span> transforming growth factor beta receptor 1 [ <em class="tax">Homo sapiens</em> (human)
]
</h1>
<span class="geneid">Gene ID: 7046, updated on
8-Mar-2025</span>
</div>
<div class="download-datasets">
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<p style="margin-left:5px;">In addition, your package will include a detailed data report in both TSV and JSONL formats.</p>
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<div class="rprt-body">
<div class="rprt-section gene-summary">
<section class="rprt-section-header" id="summary">
<h2 id="header-summary">
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</section>
<div class="rprt-section-body">
<div id="summaryDiv" class="section">
<dl id="summaryDl">
<dt class="noline"> Official
Symbol</dt>
<dd class="noline">TGFBR1<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
<dt> Official
Full Name</dt>
<dd>transforming growth factor beta receptor 1<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
<dt>Primary source</dt>
<dd>
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11772" data-gblink-text="Ensembl">HGNC:HGNC:11772</a>
</dd>
<dt>See related</dt>
<dd>
<a href="http://www.ensembl.org/id/ENSG00000106799" data-gblink-text="Ensembl" class="genome-browser-link" data-genome-browser-link-sort="5" data-gb-url="http://www.ensembl.org/loc/ENSG00000106799">Ensembl:ENSG00000106799</a>
<a href="https://www.ncbi.nlm.nih.gov/omim/190181" data-gblink-text="Ensembl" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=190181">MIM:190181;</a>
<a href="https://www.alliancegenome.org/gene/HGNC:11772" data-gblink-text="Ensembl" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=HGNC:11772">AllianceGenome:HGNC:11772</a>
</dd>
<dt>Gene type</dt>
<dd>protein coding</dd>
<dt>RefSeq status</dt>
<dd>REVIEWED</dd>
<dt>Organism</dt>
<dd class="tax">
<a href="/Taxonomy/Browser/wwwtax.cgi?id=9606" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=9606">Homo sapiens</a>
</dd>
<dt>Lineage</dt>
<dd class="tax">Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo</dd>
<dt>Also known as</dt>
<dd>AAT5; ALK5; ESS1; LDS1; MSSE; SKR4; TBRI; ALK-5; LDS1A; LDS2A; TBR-i; TGFR-1; ACVRLK4; tbetaR-I</dd>
<dt>Summary</dt>
<dd>The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]</dd>
<dt>Expression</dt>
<dd>Ubiquitous expression in placenta (RPKM 13.6), gall bladder (RPKM 8.0) and 24 other tissues <a href="#gene-expression">See more</a></dd>
<dt>Orthologs</dt>
<dd class="ortholog-links">
<a href="https://www.ncbi.nlm.nih.gov/gene/21812">mouse</a>
<a href="/gene/7046/ortholog/">all</a>
</dd>
<dt style="padding-top:.5em;">
<span class="new-icon">NEW</span>
</dt>
<dd style="padding-top:.5em;">
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/7046/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="gene_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Gene table</a></strong>
<br />
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/7046/products/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="transcript_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Transcript table</a></strong>
</dd>
</dl>
</div>
</div>
</div>
<div class="rprt-section gene-genomic-context">
<section class="rprt-section-header" id="genomic-context">
<h2 id="header-genomic-context">
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<span class="ui-ncbitoggler-master-text">Genomic context</span>
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</h2>
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</a>
</div>
</section>
<div class="rprt-section-body">
<div class="gc_cont">
<div class="gt_cont_contents">
<div style="float:right"><span>See TGFBR1 in </span><a href="/genome/gdv/?context=gene&amp;acc=7046" class="link-to-gdv genome-browser-link" data-genome-browser-link-sort="1" data-acc="GCF_000001405.40">Genome Data Viewer</a> </div>
<dl class="dl-chr-info" style="float:left;margin-top:0;">
<dt>Location: </dt>
<dd>
<span style="display:inline-block;">9q22.33</span>
</dd>
</dl>
</div>
<dl class="dl-chr-info exon-count">
<dt>Exon count: </dt>
<dd>19</dd>
</dl>
<div class="ui-ncbigrid-outer-div" id="genomic-context-tbl-location">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-jigconfig="">
<thead>
<tr>
<th style="max-width:15%">Annotation release</th>
<th style="max-width:10%">Status</th>
<th>Assembly</th>
<th>
<span title="Chromosome">Chr</span>
</th>
<th>Location</th>
</tr>
</thead>
<tbody>
<tr>
<td>RS_2024_08</td>
<td>current</td>
<td>GRCh38.p14 (<a href="/assembly/GCF_000001405.40/" ref="ncbi_uid=7046&amp;link_uid=GCF_000001405.40">GCF_000001405.40</a>)</td>
<td>9</td>
<td>NC_000009.12 (99103647..99154192) </td>
</tr>
<tr>
<td>RS_2024_08</td>
<td>current</td>
<td>T2T-CHM13v2.0 (<a href="/assembly/GCF_009914755.1/" ref="ncbi_uid=7046&amp;link_uid=GCF_009914755.1">GCF_009914755.1</a>)</td>
<td>9</td>
<td>NC_060933.1 (111275348..111325904) </td>
</tr>
<tr>
<td>RS_2024_09</td>
<td>previous assembly</td>
<td>GRCh37.p13 (<a href="/assembly/GCF_000001405.25/" ref="ncbi_uid=7046&amp;link_uid=GCF_000001405.25">GCF_000001405.25</a>)</td>
<td>9</td>
<td>NC_000009.11 (101865929..101916474) </td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
<p class="withnote margin_t2em"><strong>Chromosome 9 - NC_000009.12</strong><img usemap="#nbrMap7046_568815589" border="0" alt="Genomic Context describing neighboring genes" src="/gutils/geneneighb.fcgi?geneid=7046&amp;nuc_gi=568815589&amp;n0=ADIPINT&amp;n1=LOC116216096&amp;n2=LOC121811713&amp;n3=COL15A1&amp;n4=LOC127815459&amp;n5=LOC127815460&amp;n6=LOC127815461&amp;n7=LOC127815462&amp;n8=LOC127815463&amp;n9=LOC127815464&amp;n10=LOC127815465&amp;n11=LOC127815466&amp;n12=LOC116216097&amp;n13=TGFBR1&amp;n14=LOC130002223&amp;n15=LOC130002224&amp;n16=LOC130002225&amp;n17=RNA5SP290&amp;n18=LOC121331339&amp;n19=LOC127815467&amp;n20=LOC132089611&amp;n21=LOC127815468&amp;n22=LOC127815469&amp;n23=LOC130002226&amp;n24=LOC105376174&amp;n25=LOC130002227&amp;n26=RN7SL794P" /><map name="nbrMap7046_568815589" id="nbrMap7046_568815589">
<area shape="rect" onMouseOver="showtip(this,event,'adipocyte associated pyruvate carboxylase interacting lncRNA')" onMouseOut="hidetip()" coords="27,23,88,31" alt="Neighboring gene adipocyte associated pyruvate carboxylase interacting lncRNA" href="/gene/125906382" />
<area shape="rect" onMouseOver="showtip(this,event,'CRISPRi-validated cis-regulatory element chr9.1708')" onMouseOut="hidetip()" coords="29,35,99,43" alt="Neighboring gene CRISPRi-validated cis-regulatory element chr9.1708" href="/gene/116216096" />
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 4619')" onMouseOut="hidetip()" coords="33,47,103,55" alt="Neighboring gene Sharpr-MPRA regulatory region 4619" href="/gene/121811713" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr9:101724037-101724537')" onMouseOut="hidetip()" coords="68,59,138,67" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:101724037-101724537" href="/gene/127815459" />
<area shape="rect" onMouseOver="showtip(this,event,'OCT4-NANOG hESC enhancer GRCh37_chr9:101725038-101725622')" onMouseOut="hidetip()" coords="69,71,139,79" alt="Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr9:101725038-101725622" href="/gene/127815460" />
<area shape="rect" onMouseOver="showtip(this,event,'collagen type XV alpha 1 chain')" onMouseOut="hidetip()" coords="70,83,273,91" alt="Neighboring gene collagen type XV alpha 1 chain" href="/gene/1306" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:101733335-101733912')" onMouseOut="hidetip()" coords="80,95,150,103" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:101733335-101733912" href="/gene/127815461" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:101733913-101734490')" onMouseOut="hidetip()" coords="81,107,151,115" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:101733913-101734490" href="/gene/127815462" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr9:101760575-101761331')" onMouseOut="hidetip()" coords="116,23,186,31" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:101760575-101761331" href="/gene/127815463" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr9:101761332-101762087')" onMouseOut="hidetip()" coords="117,35,187,43" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:101761332-101762087" href="/gene/127815464" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac hESC enhancer GRCh37_chr9:101834020-101834520')" onMouseOut="hidetip()" coords="212,23,282,31" alt="Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:101834020-101834520" href="/gene/127815465" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac hESC enhancer GRCh37_chr9:101834521-101835021')" onMouseOut="hidetip()" coords="212,35,282,43" alt="Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:101834521-101835021" href="/gene/127815466" />
<area shape="rect" onMouseOver="showtip(this,event,'CRISPRi-validated cis-regulatory element chr9.1735')" onMouseOut="hidetip()" coords="216,47,286,55" alt="Neighboring gene CRISPRi-validated cis-regulatory element chr9.1735" href="/gene/116216097" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 20124')" onMouseOut="hidetip()" coords="255,59,325,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20124" href="/gene/130002223" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 20125')" onMouseOut="hidetip()" coords="256,71,326,79" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20125" href="/gene/130002224" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 28699')" onMouseOut="hidetip()" coords="297,35,367,43" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28699" href="/gene/130002225" />
<area shape="rect" onMouseOver="showtip(this,event,'RNA, 5S ribosomal pseudogene 290')" onMouseOut="hidetip()" coords="324,47,379,55" alt="Neighboring gene RNA, 5S ribosomal pseudogene 290" href="/gene/100873543" />
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 12902')" onMouseOut="hidetip()" coords="337,59,407,67" alt="Neighboring gene Sharpr-MPRA regulatory region 12902" href="/gene/121331339" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr9:101932965-101933747')" onMouseOut="hidetip()" coords="341,71,411,79" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:101932965-101933747" href="/gene/127815467" />
<area shape="rect" onMouseOver="showtip(this,event,'Neanderthal introgressed variant-containing enhancer experimental_103896')" onMouseOut="hidetip()" coords="342,83,412,91" alt="Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_103896" href="/gene/132089611" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac hESC enhancer GRCh37_chr9:101941126-101941626')" onMouseOut="hidetip()" coords="352,95,422,103" alt="Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:101941126-101941626" href="/gene/127815468" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac hESC enhancer GRCh37_chr9:101941627-101942127')" onMouseOut="hidetip()" coords="352,107,422,115" alt="Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:101941627-101942127" href="/gene/127815469" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 28700')" onMouseOut="hidetip()" coords="353,119,423,127" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28700" href="/gene/130002226" />
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC105376174')" onMouseOut="hidetip()" coords="353,131,423,139" alt="Neighboring gene uncharacterized LOC105376174" href="/gene/105376174" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 28701')" onMouseOut="hidetip()" coords="353,143,423,151" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 28701" href="/gene/130002227" />
<area shape="rect" onMouseOver="showtip(this,event,'RNA, 7SL, cytoplasmic 794, pseudogene')" onMouseOut="hidetip()" coords="368,35,423,43" alt="Neighboring gene RNA, 7SL, cytoplasmic 794, pseudogene" href="/gene/106479510" />
</map>
</p>
</div>
</div>
<div class="rprt-section gene-genomic-regions-transcripts-products">
<section class="rprt-section-header" id="genomic-regions-transcripts-products">
<h2 id="header-genomic-regions-transcripts-products">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-regions-transcripts-products .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Genomic regions, transcripts, and products</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Genomic_Regions_Transcripts_a" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div>
<div style="text-align:right;">Go to <a href="#reference-sequences">reference sequence details</a></div>
</div>
<div>
<p class="choose">
<label for="accession" class="label">Genomic Sequence: </label>
<select name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.accessionList" sid="1" id="accessionList" data-taxid="9606" data-geneid="7046">
<option value="NC_000009.12_99103646_99154191">NC_000009.12 Chromosome 9 Reference GRCh38.p14 Primary Assembly</option>
<option value="NG_007461.1_4983_54062">NG_007461.1 RefSeqGene</option>
<option value="NC_060933.1_111275347_111325903">NC_060933.1 Chromosome 9 Alternate T2T-CHM13v2.0</option>
<option value="NC_000009.11_101865928_101916473">NC_000009.11 Chromosome 9 Reference GRCh37.p13 Primary Assembly</option>
</select>
</p>
</div>
<div id="NC_000009" class="divAccession">
<div class="seq-viewer">
<p class="note-link">
<strong>Go to nucleotide:</strong>
<a title="Nucleotide Graphic report" href="/nuccore/NC_000009.12?report=graph&amp;from=99096064&amp;to=99161773&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=NC_000009.12">Graphics</a>
<a title="Nucleotide FASTA report" href="/nuccore/NC_000009.12?report=fasta&amp;from=99103647&amp;to=99154192" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=NC_000009.12">FASTA</a>
<a title="Nucleotide GenBank report" href="/nuccore/NC_000009.12?report=genbank&amp;from=99103647&amp;to=99154192" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=NC_000009.12">GenBank</a>
</p>
<div id="divNC_000009" class="SeqViewerApp" style="clear:both;" data-sv="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000009.12&amp;from=99096064&amp;to=99161773&amp;app_context=Gene&amp;assm_context=GCF_000001405.40">
<a href="?appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000009.12&amp;from=99096064&amp;to=99161773&amp;app_context=Gene&amp;assm_context=GCF_000001405.40"></a>
</div>
</div>
</div>
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000009.12" sid="1" type="hidden" id="nucleotideLink_NC_000009_12_99103646_99154191" value="&lt;p class=&quot;note-link&quot;&gt;&lt;strong&gt;Go to nucleotide:&lt;/strong&gt;&lt;a title=&quot;Nucleotide Graphic report&quot; href=&quot;/nuccore/NC_000009.12?report=graph&amp;amp;from=99096064&amp;amp;to=99161773&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.40&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7046&amp;amp;link_uid=NC_000009.12&quot;&gt;Graphics&lt;/a&gt;&lt;a title=&quot;Nucleotide FASTA report&quot; href=&quot;/nuccore/NC_000009.12?report=fasta&amp;amp;from=99103647&amp;amp;to=99154192&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7046&amp;amp;link_uid=NC_000009.12&quot;&gt;FASTA&lt;/a&gt;&lt;a title=&quot;Nucleotide GenBank report&quot; href=&quot;/nuccore/NC_000009.12?report=genbank&amp;amp;from=99103647&amp;amp;to=99154192&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7046&amp;amp;link_uid=NC_000009.12&quot;&gt;GenBank&lt;/a&gt;&lt;/p&gt;" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000009.12" sid="1" type="hidden" id="relString_NC_000009_12_99103646_99154191" value="appname=ncbigene&amp;amp;embedded=true&amp;amp;noslider=1&amp;amp;id=NC_000009.12&amp;amp;from=99096064&amp;amp;to=99161773&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.40" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NG_007461.1" sid="1" type="hidden" id="nucleotideLink_NG_007461_1_4983_54062" value="&lt;p class=&quot;note-link&quot;&gt;&lt;strong&gt;Go to nucleotide:&lt;/strong&gt;&lt;a title=&quot;Nucleotide Graphic report&quot; href=&quot;/nuccore/NG_007461.1?report=graph&amp;amp;from=1&amp;amp;to=61424&amp;amp;tracks=[key:sequence_track,name:Sequence,display_name:Sequence,category:Sequence,annots:Sequence,ShowLabel:false][key:gene_model_track,name:Genes---Unnamed,display_name:Genes,annots:Unnamed,Options:ShowAllButGenes,SNPs:false,CDSProductFeats:false,ShowLabelsForAllFeatures:true,HighlightMode:2][key:SNP_track,name:SNP,annots:SNP,Layout:Adaptive][key:SNP_Bins_track,name:Clinical Variants][key:SNP_Bins_track,name:Cited Variants][key:GWAS_track,name:GWAS Tracks,display_name:Association Results][key:alignment_track,category:Alignments,annots:Unnamed][key:alignment_track,category:Alignments,annots:NA000079160.1][key:alignment_track,category:Alignments,annots:NA000010065.1]&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7046&amp;amp;link_uid=NG_007461.1&quot;&gt;Graphics&lt;/a&gt;&lt;a title=&quot;Nucleotide FASTA report&quot; href=&quot;/nuccore/NG_007461.1?report=fasta&amp;amp;from=4984&amp;amp;to=54063&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7046&amp;amp;link_uid=NG_007461.1&quot;&gt;FASTA&lt;/a&gt;&lt;a title=&quot;Nucleotide GenBank report&quot; href=&quot;/nuccore/NG_007461.1?report=genbank&amp;amp;from=4984&amp;amp;to=54063&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7046&amp;amp;link_uid=NG_007461.1&quot;&gt;GenBank&lt;/a&gt;&lt;/p&gt;" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NG_007461.1" sid="1" type="hidden" id="relString_NG_007461_1_4983_54062" value="appname=ncbigene&amp;amp;embedded=true&amp;amp;noslider=1&amp;amp;id=NG_007461.1&amp;amp;from=1&amp;amp;to=61424&amp;amp;tracks=[key:sequence_track,name:Sequence,display_name:Sequence,category:Sequence,annots:Sequence,ShowLabel:false][key:gene_model_track,name:Genes---Unnamed,display_name:Genes,annots:Unnamed,Options:ShowAllButGenes,SNPs:false,CDSProductFeats:false,ShowLabelsForAllFeatures:true,HighlightMode:2][key:SNP_track,name:SNP,annots:SNP,Layout:Adaptive][key:SNP_Bins_track,name:Clinical Variants][key:SNP_Bins_track,name:Cited Variants][key:GWAS_track,name:GWAS Tracks,display_name:Association Results][key:alignment_track,category:Alignments,annots:Unnamed][key:alignment_track,category:Alignments,annots:NA000079160.1][key:alignment_track,category:Alignments,annots:NA000010065.1]" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_060933.1" sid="1" type="hidden" id="nucleotideLink_NC_060933_1_111275347_111325903" value="&lt;p class=&quot;note-link&quot;&gt;&lt;strong&gt;Go to nucleotide:&lt;/strong&gt;&lt;a title=&quot;Nucleotide Graphic report&quot; href=&quot;/nuccore/NC_060933.1?report=graph&amp;amp;from=111267764&amp;amp;to=111333486&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_009914755.1&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7046&amp;amp;link_uid=NC_060933.1&quot;&gt;Graphics&lt;/a&gt;&lt;a title=&quot;Nucleotide FASTA report&quot; href=&quot;/nuccore/NC_060933.1?report=fasta&amp;amp;from=111275348&amp;amp;to=111325904&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7046&amp;amp;link_uid=NC_060933.1&quot;&gt;FASTA&lt;/a&gt;&lt;a title=&quot;Nucleotide GenBank report&quot; href=&quot;/nuccore/NC_060933.1?report=genbank&amp;amp;from=111275348&amp;amp;to=111325904&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7046&amp;amp;link_uid=NC_060933.1&quot;&gt;GenBank&lt;/a&gt;&lt;/p&gt;" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_060933.1" sid="1" type="hidden" id="relString_NC_060933_1_111275347_111325903" value="appname=ncbigene&amp;amp;embedded=true&amp;amp;noslider=1&amp;amp;id=NC_060933.1&amp;amp;from=111267764&amp;amp;to=111333486&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_009914755.1" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000009.11" sid="1" type="hidden" id="nucleotideLink_NC_000009_11_101865928_101916473" value="&lt;p class=&quot;note-link&quot;&gt;&lt;strong&gt;Go to nucleotide:&lt;/strong&gt;&lt;a title=&quot;Nucleotide Graphic report&quot; href=&quot;/nuccore/NC_000009.11?report=graph&amp;amp;from=101858346&amp;amp;to=101924055&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.25&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7046&amp;amp;link_uid=NC_000009.11&quot;&gt;Graphics&lt;/a&gt;&lt;a title=&quot;Nucleotide FASTA report&quot; href=&quot;/nuccore/NC_000009.11?report=fasta&amp;amp;from=101865929&amp;amp;to=101916474&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7046&amp;amp;link_uid=NC_000009.11&quot;&gt;FASTA&lt;/a&gt;&lt;a title=&quot;Nucleotide GenBank report&quot; href=&quot;/nuccore/NC_000009.11?report=genbank&amp;amp;from=101865929&amp;amp;to=101916474&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=7046&amp;amp;link_uid=NC_000009.11&quot;&gt;GenBank&lt;/a&gt;&lt;/p&gt;" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000009.11" sid="1" type="hidden" id="relString_NC_000009_11_101865928_101916473" value="appname=ncbigene&amp;amp;embedded=true&amp;amp;noslider=1&amp;amp;id=NC_000009.11&amp;amp;from=101858346&amp;amp;to=101924055&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.25" />
</div>
</div>
<div class="rprt-section gene-gene-expression">
<section class="rprt-section-header" id="gene-expression">
<h2 id="header-gene-expression">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-gene-expression .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Expression</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Expression" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div>
<div style="text-align:right;">
<a href="/gene/7046/?report=expression" data-url="/gene/7046/?report=expression" id="gene-expression-see-details">See details</a>
</div>
<div id="gene-expression-app" data-url="https://www.ncbi.nlm.nih.gov/gene/7046" data-report-type="summary">
<div>
<script type="text/javascript">
window.tissues_data = {'adrenal 10wk': {'id': '7046_Adrenal_10wk_PRJNA270632', 'gene': 7046, 'source_name': 'adrenal 10wk', 'full_rpkm': 5.64005, 'exp_rpkm': 5.64, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734405942149160}, 'adrenal 16wk': {'id': '7046_Adrenal_16wk_PRJNA270632', 'gene': 7046, 'source_name': 'adrenal 16wk', 'full_rpkm': 3.07156, 'exp_rpkm': 3.07, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734405942149161}, 'adrenal 18wk': {'id': '7046_Adrenal_18wk_PRJNA270632', 'gene': 7046, 'source_name': 'adrenal 18wk', 'full_rpkm': 4.1889, 'exp_rpkm': 4.19, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734405942149162}, 'adrenal 20wk': {'id': '7046_Adrenal_20wk_PRJNA270632', 'gene': 7046, 'source_name': 'adrenal 20wk', 'full_rpkm': 2.91403, 'exp_rpkm': 2.91, 'var': 0.455064, 'project_desc': 'PRJNA270632', '_version_': 1785734405942149163}, 'heart 10wk': {'id': '7046_Heart_10wk;_PRJNA270632', 'gene': 7046, 'source_name': 'heart 10wk', 'full_rpkm': 8.60764, 'exp_rpkm': 8.61, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734405942149164}, 'heart 11wk': {'id': '7046_Heart_11wk;_PRJNA270632', 'gene': 7046, 'source_name': 'heart 11wk', 'full_rpkm': 5.50111, 'exp_rpkm': 5.5, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734405943197696}, 'heart 17wk': {'id': '7046_Heart_17wk;_PRJNA270632', 'gene': 7046, 'source_name': 'heart 17wk', 'full_rpkm': 3.72307, 'exp_rpkm': 3.72, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734405943197697}, 'heart 18wk': {'id': '7046_Heart_18wk;_PRJNA270632', 'gene': 7046, 'source_name': 'heart 18wk', 'full_rpkm': 3.50942, 'exp_rpkm': 3.51, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734405943197698}, 'heart 20wk': {'id': '7046_Heart_20wk_PRJNA270632', 'gene': 7046, 'source_name': 'heart 20wk', 'full_rpkm': 4.49747, 'exp_rpkm': 4.5, 'var': 1.170126, 'project_desc': 'PRJNA270632', '_version_': 1785734405943197699}, 'intestine 10wk': {'id': '7046_Intestine_10wk_PRJNA270632', 'gene': 7046, 'source_name': 'intestine 10wk', 'full_rpkm': 7.12298, 'exp_rpkm': 7.12, 'var': 4.12772, 'project_desc': 'PRJNA270632', '_version_': 1785734405943197700}, 'intestine 11wk': {'id': '7046_Intestine_11wk_PRJNA270632', 'gene': 7046, 'source_name': 'intestine 11wk', 'full_rpkm': 8.23723, 'exp_rpkm': 8.24, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734405943197701}, 'intestine 15wk': {'id': '7046_Intestine_15wk_PRJNA270632', 'gene': 7046, 'source_name': 'intestine 15wk', 'full_rpkm': 5.21716, 'exp_rpkm': 5.22, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734405943197702}, 'intestine 17wk': {'id': '7046_Intestine_17wk_PRJNA270632', 'gene': 7046, 'source_name': 'intestine 17wk', 'full_rpkm': 2.97985, 'exp_rpkm': 2.98, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734405943197703}, 'intestine 20wk': {'id': '7046_Intestine_20wk_PRJNA270632', 'gene': 7046, 'source_name': 'intestine 20wk', 'full_rpkm': 7.46947, 'exp_rpkm': 7.47, 'var': 1.052646, 'project_desc': 'PRJNA270632', '_version_': 1785734405943197704}, 'kidney 10wk': {'id': '7046_Kidney_10wk_PRJNA270632', 'gene': 7046, 'source_name': 'kidney 10wk', 'full_rpkm': 8.61175, 'exp_rpkm': 8.61, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734405943197705}, 'kidney 16wk': {'id': '7046_Kidney_16wk_PRJNA270632', 'gene': 7046, 'source_name': 'kidney 16wk', 'full_rpkm': 3.1362, 'exp_rpkm': 3.14, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734405943197706}, 'kidney 20wk': {'id': '7046_Kidney_20wk_PRJNA270632', 'gene': 7046, 'source_name': 'kidney 20wk', 'full_rpkm': 1.54692, 'exp_rpkm': 1.55, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734405943197707}, 'lung 10wk': {'id': '7046_Lung_10wk_PRJNA270632', 'gene': 7046, 'source_name': 'lung 10wk', 'full_rpkm': 6.38947, 'exp_rpkm': 6.39, 'var': 0.1329, 'project_desc': 'PRJNA270632', '_version_': 1785734405943197708}, 'lung 17wk': {'id': 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<select name="p" id="project-selector">
<option value="SRP051249" selected="selected" data-bioproject="PRJNA270632">
Tissue-specific circular RNA induction during human fetal development
</option>
<option value="SRP056969" data-bioproject="PRJNA280600">
RNA sequencing of total RNA from 20 human tissues
</option>
<option value="ERP003613" data-bioproject="PRJEB4337">
HPA RNA-seq normal tissues
</option>
</select>
<ul id="project-summary">
<li id="project-summary-title">Project title:
Tissue-specific circular RNA induction during human fetal development
</li>
<li id="project-summary-desc">Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA</li>
<li id="project-summary-bioprojects">BioProject: <a href="/bioproject/PRJNA270632/">PRJNA270632</a>
</li>
<li id="project-summary-pubs">Publication:
<span><a href="/pubmed/26076956/">PMID 26076956</a></span>
</li>
<li id="project-summary-analysis-date">Analysis date: Mon Apr 2 22:54:59 2018</li>
</ul>
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<a href="#" class="jig-ncbitoggler-open">GeneRIFs: Gene References Into Functions</a>
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</li>
<li class="gene-rif-popper">
<a href="/pubmed/39333849" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=39333849">CD9 promotes TbetaR2-TbetaR1 association driving the transition of human dermal fibroblasts to myofibroblast under hypoxia.</a>
<div id="gene-popper2" class="gene-rif-popper">Title: CD9 promotes TβR2-TβR1 association driving the transition of human dermal fibroblasts to myofibroblast under hypoxia.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/38981014" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=38981014">Stabilization of TGF-beta Receptor 1 by a Receptor-Associated Adaptor Dictates Feedback Activation of the TGF-beta Signaling Pathway to Maintain Liver Cancer Stemness and Drug Resistance.</a>
<div id="gene-popper3" class="gene-rif-popper">Title: Stabilization of TGF-β Receptor 1 by a Receptor-Associated Adaptor Dictates Feedback Activation of the TGF-β Signaling Pathway to Maintain Liver Cancer Stemness and Drug Resistance.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/39113797" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=39113797">ISG15 accelerates acute kidney injury and the subsequent AKI-to-CKD transition by promoting TGFbetaR1 ISGylation.</a>
<div id="gene-popper4" class="gene-rif-popper">Title: ISG15 accelerates acute kidney injury and the subsequent AKI-to-CKD transition by promoting TGFβR1 ISGylation.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/38730107" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=38730107">Polymorphism of Transforming Growth Factor TGFB and Its Receptors TGFBRI, TGFBRII, TGFBRIIII Genes in Western Siberia Patients with Open-Angle Glaucoma.</a>
<div id="gene-popper5" class="gene-rif-popper">Title: Polymorphism of Transforming Growth Factor TGFB and Its Receptors TGFBRI, TGFBRII, TGFBRIIII Genes in Western Siberia Patients with Open-Angle Glaucoma.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/38582012" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=38582012">Gut microbiota regulates the ALK5/NOX1 axis by altering glutamine metabolism to inhibit ferroptosis of intrahepatic cholangiocarcinoma cells.</a>
<div id="gene-popper6" class="gene-rif-popper">Title: Gut microbiota regulates the ALK5/NOX1 axis by altering glutamine metabolism to inhibit ferroptosis of intrahepatic cholangiocarcinoma cells.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/38522762" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=38522762">Blockade of endothelial adenosine receptor 2 A suppresses atherosclerosis in vivo through inhibiting CREB-ALK5-mediated endothelial to mesenchymal transition.</a>
<div id="gene-popper7" class="gene-rif-popper">Title: Blockade of endothelial adenosine receptor 2A suppresses atherosclerosis in vivo through inhibiting CREB-ALK5-mediated endothelial to mesenchymal transition.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/38328944" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=38328944">TGFbetaR1 inhibition drives hepatocellular carcinoma proliferation through induction of toll-like-receptor signalling.</a>
<div id="gene-popper8" class="gene-rif-popper">Title: TGFβR1 inhibition drives hepatocellular carcinoma proliferation through induction of toll-like-receptor signalling.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/37743142" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=37743142">Exosomes from human adipose-derived mesenchymal stem cells attenuate localized scleroderma fibrosis by the let-7a-5p/TGF-betaR1/Smad axis.</a>
<div id="gene-popper9" class="gene-rif-popper">Title: Exosomes from human adipose-derived mesenchymal stem cells attenuate localized scleroderma fibrosis by the let-7a-5p/TGF-βR1/Smad axis.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/37327315" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=37327315">Functional Genetic Variants in TGFbeta1 and TGFbetaR1 in miRNA-Binding Sites Predict Outcomes in Patients with HPV-positive Oropharyngeal Squamous Cell Carcinoma.</a>
<div id="gene-popper10" class="gene-rif-popper">Title: Functional Genetic Variants in TGFβ1 and TGFβR1 in miRNA-Binding Sites Predict Outcomes in Patients with HPV-positive Oropharyngeal Squamous Cell Carcinoma.</div>
</li>
</ol>
</div>
<div class="submit-genrif">
<span>Submit:</span>
<a href="/gene/submit-generif/?geneId=7046&amp;sym=TGFBR1&amp;name=transforming growth factor beta receptor 1&amp;org=Homo sapiens">New GeneRIF</a>
<a href="/RefSeq/update.cgi?geneid=7046&amp;symbol=TGFBR1;task=fixpub">Correction</a>
<a href="https://www.ncbi.nlm.nih.gov/gene?db=gene&amp;report=generif&amp;term=7046" class="seeall-generif">See all GeneRIFs (370)</a>
</div>
</div>
</div>
</div>
</div>
<div class="rprt-section gene-phenotypes">
<section class="rprt-section-header" id="phenotypes">
<h2 id="header-phenotypes">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-phenotypes .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Phenotypes</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Phenotype" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body info-phenotype">
<p class="nochild-link">
<a href="/gtr/tests/?term=TGFBR1[gene]">Find tests for this gene in the NIH Genetic Testing Registry (GTR)</a>
</p>
<p class="nochild-link">
<a href="/gap/PheGenI?tab=1&amp;gene=7046">Review eQTL and phenotype association data in this region using PheGenI</a>
</p>
<div>
<h3 id="professionalguidelines">Professional guidelines</h3>
<table class="jig-ncbigrid gtr-associated-cond" data-jigconfig="isPageable: true, pageSize: 10">
<thead>
<tr>
<th class="description">Description</th>
</tr>
</thead>
<tbody>
<tr>
<td>Professional guideline<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">ACMG 2013</span><div><p>The ACMG recommends that laboratories performing clinical sequencing seek and report mutations in TGFBR1 that are pathogenic or expected to be pathogenic.</p><span class="gtr-associated-cond-extra-i"><a href="http://www.acmg.net/docs/ACMG_Releases_Highly-Anticipated_Recommendations_on_Incidental_Findings_in_Clinical_Exome_and_Genome_Sequencing.pdf">Guideline</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/23788249">PubMed</a></span></div></div></div></td>
</tr>
</tbody>
</table>
</div>
<div>
<h3 id="associatedconditions">Associated conditions</h3>
<table class="jig-ncbigrid gtr-associated-cond">
<thead>
<tr>
<th class="description">Description</th>
<th>Tests</th>
</tr>
</thead>
<tbody>
<tr>
<td>
<a href="/gtr/conditions/C4707243" ref="ncbi_uid=7046&amp;link_uid=C4707243">Familial thoracic aortic aneurysm and aortic dissection</a>
<div class="gtr-associated-cond-extra">
<span class="gtr-associated-cond-extra-i">MedGen: <a href="/medgen/C4707243" ref="ncbi_uid=7046&amp;link_uid=C4707243">C4707243</a></span>
<span class="gtr-associated-cond-extra-i">GeneReviews: <a href="/books/NBK1120" ref="ncbi_uid=7046">Heritable Thoracic Aortic Disease Overview</a></span>
</div>
</td>
<td>
<a href="/gtr/tests/?term=C4707243[DISCUI]&amp;condition=C4707243&amp;compare_labs=1" ref="ncbi_uid=7046">Compare labs</a>
</td>
</tr>
<tr>
<td>
<a href="/gtr/conditions/C4551955" ref="ncbi_uid=7046&amp;link_uid=C4551955">Loeys-Dietz syndrome 1</a>
<div class="gtr-associated-cond-extra">
<span class="gtr-associated-cond-extra-i">MedGen: <a href="/medgen/C4551955" ref="ncbi_uid=7046&amp;link_uid=C4551955">C4551955</a></span>
<span class="gtr-associated-cond-extra-i">OMIM: <a href="https://www.ncbi.nlm.nih.gov/omim/609192" ref="ncbi_uid=7046"> 609192</a></span>
<span class="gtr-associated-cond-extra-i">GeneReviews: <a href="/books/NBK1133" ref="ncbi_uid=7046">Loeys-Dietz Syndrome</a></span>
</div>
</td>
<td>
<a href="/gtr/tests/?term=C4551955[DISCUI]&amp;condition=C4551955&amp;compare_labs=1" ref="ncbi_uid=7046">Compare labs</a>
</td>
</tr>
<tr>
<td>
<a href="/gtr/conditions/C0546476" ref="ncbi_uid=7046&amp;link_uid=C0546476">Multiple self-healing squamous epithelioma</a>
<div class="gtr-associated-cond-extra">
<span class="gtr-associated-cond-extra-i">MedGen: <a href="/medgen/C0546476" ref="ncbi_uid=7046&amp;link_uid=C0546476">C0546476</a></span>
<span class="gtr-associated-cond-extra-i">OMIM: <a href="https://www.ncbi.nlm.nih.gov/omim/132800" ref="ncbi_uid=7046"> 132800</a></span>
<span class="gtr-associated-cond-extra-i">GeneReviews: <span>Not available</span></span>
</div>
</td>
<td>
<a href="/gtr/tests/?term=C0546476[DISCUI]&amp;condition=C0546476&amp;compare_labs=1" ref="ncbi_uid=7046">Compare labs</a>
</td>
</tr>
</tbody>
</table>
</div>
<div>
<h3 id="copynumberresponse">Copy number response</h3>
<table class="jig-ncbigrid gtr-associated-cond" data-jigconfig="isPageable: true, pageSize: 10">
<thead>
<tr>
<th class="description">Description</th>
</tr>
</thead>
<tbody>
<tr>
<td>Copy number response<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">Triplosensitivity</span><div><p>No evidence available (Last evaluated 2024-02-13)</p><span class="gtr-associated-cond-extra-i"><a href="https://www.ncbi.nlm.nih.gov/projects/dbvar/ISCA/isca_gene.cgi?sym=TGFBR1">ClinGen Genome Curation Page</a></span></div></div><div class="gtr-associated-cond-extra-c"><span style="color:#000;">Haploinsufficency</span><div><p>Sufficient evidence for dosage pathogenicity (Last evaluated 2024-02-13)</p><span class="gtr-associated-cond-extra-i"><a href="https://www.ncbi.nlm.nih.gov/projects/dbvar/ISCA/isca_gene.cgi?sym=TGFBR1">ClinGen Genome Curation Page</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/21358634,25525159,29706644,33256177">PubMed</a></span></div></div></div></td>
</tr>
</tbody>
</table>
</div>
<div>
<h3 id="ebigwascatalog">EBI GWAS Catalog</h3>
<table class="jig-ncbigrid gtr-associated-cond" data-jigconfig="isPageable: true, pageSize: 10">
<thead>
<tr>
<th class="description">Description</th>
</tr>
</thead>
<tbody>
<tr>
<td>Genetics of callous-unemotional behavior in children.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/23874384">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/23874384">PubMed</a></span></div></div></div></td>
</tr>
<tr>
<td>Genome-wide association study identifies new susceptibility loci for epithelial ovarian cancer in Han Chinese women.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/25134534">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/25134534">PubMed</a></span></div></div></div></td>
</tr>
<tr>
<td>GWAS of dental caries patterns in the permanent dentition.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/23064961">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/23064961">PubMed</a></span></div></div></div></td>
</tr>
<tr>
<td>Seven new loci associated with age-related macular degeneration.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/23455636">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/23455636">PubMed</a></span></div></div></div></td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
<div class="rprt-section gene-variation">
<section class="rprt-section-header" id="variation">
<h2 id="header-variation">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-variation .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Variation</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.variation" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<p class="nochild-link">
<a href="/clinvar/?term=TGFBR1[gene]" ref="log$=recordlinks">See variants in ClinVar</a>
</p>
<p class="nochild-link">
<a href="/dbvar?LinkName=gene_dbvar&amp;from_uid=7046" ref="log$=recordlinks">See studies and variants in dbVar</a>
</p>
<p class="nochild-link">
<a href="/variation/view/?q=7046[geneid]&amp;assm=GCF_000001405.25" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh37.p13)">See Variation Viewer (GRCh37.p13)</a>
</p>
<p class="nochild-link">
<a href="/variation/view/?q=7046[geneid]" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh38)">See Variation Viewer (GRCh38)</a>
</p>
<set></set>
<set></set>
</div>
</div>
<div class="rprt-section gene-HIV-1-interactions">
<section class="rprt-section-header" id="HIV-1-interactions">
<h2 id="header-HIV-1-interactions">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-HIV-1-interactions .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">HIV-1 interactions</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.HIV1_interactions" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div class="fgrid">
<h3 id="proteininteractions">Protein interactions</h3>
<table summary="protein interactions" class="jig-ncbigrid">
<thead>
<tr>
<th id="hivprotein">Protein</th>
<th id="gene-hivprotein">Gene</th>
<th id="hivinter">Interaction</th>
<th id="hivpub">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="hivprotein">
<a href="/protein/9629366">Vpu</a>
</td>
<td headers="gene-hivprotein">
<a href="/gene/155945">vpu</a>
</td>
<td headers="hivinter">Antibodies against TGF-beta or a TGF-beta receptor inhibitor SB431452 reverse HIV-1 Vpu-mediated profibrogenic activation of LX2 cells, suggesting that TGF-beta mediates these effects</td>
<td headers="hivpub">
<a title="PubMed Id(s): 24551192" href="/pubmed/24551192">PubMed</a>
</td>
</tr>
</tbody>
</table>
<p class="withnote">
<a class="note" href="/genome/viruses/retroviruses/hiv-1/interactions/">Go to the HIV-1, Human Interaction Database </a>
</p>
</div>
</div>
</div>
<div class="rprt-section gene-pathways">
<section class="rprt-section-header" id="pathways">
<h2 id="header-pathways">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-pathways .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Pathways from PubChem</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<ul class="geneinfo-subsec infopathway">
<iframe title="Pathways in which the gene target is involved" class="pubchem-widget" scrolling="no" src="https://pubchem.ncbi.nlm.nih.gov/gene/7046#section=Pathways&amp;embed=true&amp;hide_all_headings=true&amp;page_size=25" style="border: 0; width: 100%;"></iframe>
<script type="text/javascript" src="https://pubchem.ncbi.nlm.nih.gov/pcfe/libs/iframeResizer.min.js"></script>
<script type="text/javascript">iFrameResize({log: false, checkOrigin: false}, '.pubchem-widget')</script>
</ul>
</div>
</div>
<div class="rprt-section gene-interactions">
<section class="rprt-section-header" id="interactions">
<h2 id="header-interactions">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-interactions .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Interactions</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Interactions" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<table summary="Gene Interaction" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/7046/data/interaction/',webserviceParams: 'p$l=Ajax&amp;p$debugoutput=off', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
<thead>
<tr>
<th id="inter-prod">Products</th>
<th id="inter-interactant">Interactant</th>
<th id="inter-otherGene">Other Gene</th>
<th id="inter-compl">Complex</th>
<th id="inter-source">Source</th>
<th id="inter-pubs">Pubs</th>
<th id="inter-desc">Description</th>
</tr>
</thead>
<tbody></tbody>
</table>
</div>
</div>
<div class="rprt-section gene-general-gene-info">
<section class="rprt-section-header" id="general-gene-info">
<h2 id="header-general-gene-info">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-gene-info .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">General gene information</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.General_Gene_Information" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body" style="">
<div id="gene-markers">
<h3 id="markers">
<a class="jig-ncbitoggler">Markers</a>
</h3>
<div>
<ul class="marker odd">
<li class="marker">RH35823 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=25098%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=25098">UniSTS:25098</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">RH121979 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=137747%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=137747">UniSTS:137747</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">SHGC-57485 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=31771%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=31771">UniSTS:31771</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">RH69005 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=72996%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=72996">UniSTS:72996</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">SHGC-12551 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=37420%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=37420">UniSTS:37420</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">TGFBR1_1095 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=277808%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=277808">UniSTS:277808</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">GDB:437164 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=157239%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=157239">UniSTS:157239</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">RH45434 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=33095%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=33095">UniSTS:33095</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">RH45880 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=40540%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=40540">UniSTS:40540</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">D9S2089 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=70764%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=70764">UniSTS:70764</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">SHGC-78743 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=95601%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=95601">UniSTS:95601</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">SHGC-12551 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=4731%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=4731">UniSTS:4731</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">Tgfbr1 (e-PCR), detects polymorphism<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=496000%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=496000">UniSTS:496000</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">SHGC-34660 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=79773%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=79773">UniSTS:79773</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">SHGC-147856 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=176054%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=176054">UniSTS:176054</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">RH45113 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=38612%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=38612">UniSTS:38612</a></li></ul></li>
</ul>
</div>
</div>
<div>
<div class="infosec" id="Relatedpseudogenes"><h3 id="relatedpseudogenes"><a class="jig-ncbitoggler-open">Related pseudogene(s)</a></h3>
<dl class="geneinfo-subsec"><dt>1 found
 
<a href="/gene/?Term=related_functional_gene_7046%5Bgroup%5D">Review record(s) in Gene</a></dt></dl>
</div>
</div>
<div class="infosec">
<h3 id="homology">
<a class="jig-ncbitoggler-open">Homology</a>
</h3>
<ul class="geneinfo-subsec">
<li>
<a href="/gene/7046/ortholog/" id="ncbi-ortholog-link">NCBI Orthologs</a>
</li>
<a href="https://www.orthodb.org/?ncbi=7046" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8178" target="_blank">
Orthologs from OrthoDB
</a>
</ul>
</div>
<!--<component id="Gene_InfoPathway"/>-->
<div class="gene-ontology infosec">
<h3 id="gene-ontology">
<a class="jig-ncbitoggler-open">
<span>Gene Ontology</span>
</a>
<a target="_blank" href="http://www.ebi.ac.uk/GOA" class="g-ontology-src" title="Provided by GOA">Provided by GOA</a>
</h3>
<div class="ontology-tables">
<div class="ui-ncbigrid-outer-div">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
<thead>
<tr>
<th class="col1">Function</th>
<th style="width:12%;">Evidence Code</th>
<th style="width:10%;">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005524">enables ATP binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-1-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/12065756" target="_blank" title="PubMed ID 12065756" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=12065756">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0098821">enables BMP receptor activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-2-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0070411">enables I-SMAD binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
<div id="evidence-code-3-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/11278251" target="_blank" title="PubMed ID 11278251" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=11278251">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0046332">enables SMAD binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-4-0" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0046332">enables SMAD binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-5-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/12065756,18625725" target="_blank" title="PubMed ID 12065756,18625725" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=12065756,18625725">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0046332">enables SMAD binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
<div id="evidence-code-6-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/8980228,9311995" target="_blank" title="PubMed ID 8980228,9311995" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=8980228,9311995">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0048185">enables activin binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-7-0" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0016361">enables activin receptor activity, type I</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-8-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-8-0" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0016362">enables activin receptor activity, type II</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-9-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-9-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0019838">contributes_to growth factor binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-10-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
<div id="evidence-code-10-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/14517293" target="_blank" title="PubMed ID 14517293" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=14517293">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0046872">enables metal ion binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-11-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-11-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005515">enables protein binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-12-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
<div id="evidence-code-12-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/8622651,10025408,11278302,11279102,11583628,12015308,14517293,14580334,15702480,15761148,17099224,18243111,18625725,18758450,18974388,19732720,20856203,21791611,22344298,23723426,23868260,24263861,24658140,25893292,26583432" target="_blank" title="PubMed ID 8622651,10025408,11278302,11279102,11583628,12015308,14517293,14580334,15702480,15761148,17099224,18243111,18625725,18758450,18974388,19732720,20856203,21791611,22344298,23723426,23868260,24263861,24658140,25893292,26583432" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=8622651,10025408,11278302,11279102,11583628,12015308,14517293,14580334,15702480,15761148,17099224,18243111,18625725,18758450,18974388,19732720,20856203,21791611,22344298,23723426,23868260,24263861,24658140,25893292,26583432">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0004672">enables protein kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-13-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-13-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/19736306" target="_blank" title="PubMed ID 19736306" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=19736306">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0004674">enables protein serine/threonine kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-14-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-14-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/12065756,18625725" target="_blank" title="PubMed ID 12065756,18625725" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=12065756,18625725">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0050431">contributes_to transforming growth factor beta binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-15-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-15-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/11157754" target="_blank" title="PubMed ID 11157754" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=11157754">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0050431">enables transforming growth factor beta binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-16-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-16-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/14633705" target="_blank" title="PubMed ID 14633705" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=14633705">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0050431">contributes_to transforming growth factor beta binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-17-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-17-0" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/1333888" target="_blank" title="PubMed ID 1333888" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=1333888">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0050431">enables transforming growth factor beta binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-18-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
<div id="evidence-code-18-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/1326540" target="_blank" title="PubMed ID 1326540" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=1326540">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0050431">enables transforming growth factor beta binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-19-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-19-0" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005024">enables transforming growth factor beta receptor activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-20-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IC</a>
<div id="evidence-code-20-0" class="ecode">Inferred by Curator<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/1326540" target="_blank" title="PubMed ID 1326540" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=1326540">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005024">enables transforming growth factor beta receptor activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-21-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-21-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/12015308,12065756,14633705" target="_blank" title="PubMed ID 12015308,12065756,14633705" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=12015308,12065756,14633705">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005024">contributes_to transforming growth factor beta receptor activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-22-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-22-0" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/1333888" target="_blank" title="PubMed ID 1333888" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=1333888">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005024">enables transforming growth factor beta receptor activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-23-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-23-0" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/18625725" target="_blank" title="PubMed ID 18625725" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=18625725">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005025">enables transforming growth factor beta receptor activity, type I</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-24-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-24-0" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005025">enables transforming growth factor beta receptor activity, type I</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-25-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-25-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/8752209" target="_blank" title="PubMed ID 8752209" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=8752209">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005025">enables transforming growth factor beta receptor activity, type I</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-26-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-26-0" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005026">enables transforming growth factor beta receptor activity, type II</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-27-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-27-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0070123">enables transforming growth factor beta receptor activity, type III</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-28-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-28-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0004675">enables transmembrane receptor protein serine/threonine kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-29-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-29-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/12015308,19736306" target="_blank" title="PubMed ID 12015308,19736306" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=12015308,19736306">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005114">enables type II transforming growth factor beta receptor binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-30-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-30-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/11157754" target="_blank" title="PubMed ID 11157754" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=11157754">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005114">enables type II transforming growth factor beta receptor binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-31-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
<div id="evidence-code-31-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/1333888" target="_blank" title="PubMed ID 1333888" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=1333888">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0031625">enables ubiquitin protein ligase binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-32-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
<div id="evidence-code-32-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/12151385" target="_blank" title="PubMed ID 12151385" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=12151385">PubMed</a> </td>
</tr>
</tbody>
</table>
</div>
</div>
<div class="ui-ncbigrid-outer-div">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
<thead>
<tr>
<th class="col1">Process</th>
<th style="width:12%;">Evidence Code</th>
<th style="width:10%;">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0030509">involved_in BMP signaling pathway</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-1-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0032924">involved_in activin receptor signaling pathway</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-2-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0032924">involved_in activin receptor signaling pathway</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-3-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0060978">involved_in angiogenesis involved in coronary vascular morphogenesis</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-4-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0009952">involved_in anterior/posterior pattern specification</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-5-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0006915">involved_in apoptotic process</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-6-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0048844">involved_in artery morphogenesis</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-7-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0001824">involved_in blastocyst development</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-8-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-8-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0060317">involved_in cardiac epithelial to mesenchymal transition</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-9-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-9-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0048870">involved_in cell motility</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-10-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-10-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/18625725" target="_blank" title="PubMed ID 18625725" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=18625725">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0071363">involved_in cellular response to growth factor stimulus</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-11-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-11-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0071560">involved_in cellular response to transforming growth factor beta stimulus</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-12-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-12-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/19494318" target="_blank" title="PubMed ID 19494318" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=19494318">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0030199">involved_in collagen fibril organization</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-13-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-13-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0060982">involved_in coronary artery morphogenesis</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-14-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-14-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0048701">involved_in embryonic cranial skeleton morphogenesis</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-15-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-15-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0042118">involved_in endothelial cell activation</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-16-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-16-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0043542">involved_in endothelial cell migration</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-17-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-17-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:1905223">involved_in epicardium morphogenesis</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-18-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-18-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0001837">involved_in epithelial to mesenchymal transition</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-19-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-19-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/15761148" target="_blank" title="PubMed ID 15761148" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=15761148">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0043062">involved_in extracellular structure organization</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-20-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-20-1" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/9759503" target="_blank" title="PubMed ID 9759503" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=9759503">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0046847">involved_in filopodium assembly</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-21-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-21-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0008354">involved_in germ cell migration</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-22-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-22-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0007507">involved_in heart development</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-23-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-23-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0007507">involved_in heart development</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-24-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-24-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0001701">involved_in in utero embryonic development</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-25-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-25-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0035556">involved_in intracellular signal transduction</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-26-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-26-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0001822">involved_in kidney development</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-27-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-27-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0002088">involved_in lens development in camera-type eye</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-28-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-28-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0008584">involved_in male gonad development</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-29-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-29-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0048762">involved_in mesenchymal cell differentiation</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-30-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-30-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0048762">involved_in mesenchymal cell differentiation</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-31-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-31-1" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/9759503" target="_blank" title="PubMed ID 9759503" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=9759503">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0036446">involved_in myofibroblast differentiation</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-32-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-32-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/28251559" target="_blank" title="PubMed ID 28251559" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=28251559">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0030336">acts_upstream_of negative regulation of cell migration</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-33-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-33-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/23424236" target="_blank" title="PubMed ID 23424236" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=23424236">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0032331">involved_in negative regulation of chondrocyte differentiation</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-34-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-34-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0001937">involved_in negative regulation of endothelial cell proliferation</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-35-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-35-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:2001237">involved_in negative regulation of extrinsic apoptotic signaling pathway</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-36-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-36-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/18625725" target="_blank" title="PubMed ID 18625725" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=18625725">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0007399">involved_in nervous system development</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-37-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-37-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0048663">involved_in neuron fate commitment</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-38-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-38-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0060017">involved_in parathyroid gland development</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-39-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-39-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0018105">involved_in peptidyl-serine phosphorylation</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-40-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-40-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/15761148" target="_blank" title="PubMed ID 15761148" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=15761148">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0060037">involved_in pharyngeal system development</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-41-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-41-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0045893">involved_in positive regulation of DNA-templated transcription</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-42-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-42-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/9311995,9389648" target="_blank" title="PubMed ID 9311995,9389648" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=9311995,9389648">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0045893">involved_in positive regulation of DNA-templated transcription</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-43-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-43-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0060391">involved_in positive regulation of SMAD protein signal transduction</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-44-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-44-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/9311995,9389648,11157754,12015308,18625725,19736306" target="_blank" title="PubMed ID 9311995,9389648,11157754,12015308,18625725,19736306" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=9311995,9389648,11157754,12015308,18625725,19736306">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0060391">involved_in positive regulation of SMAD protein signal transduction</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-45-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IGI</a>
<div id="evidence-code-45-1" class="ecode">Inferred from Genetic Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/22714950" target="_blank" title="PubMed ID 22714950" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=22714950">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0060391">involved_in positive regulation of SMAD protein signal transduction</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-46-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-46-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/27693460" target="_blank" title="PubMed ID 27693460" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=27693460">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:2001235">involved_in positive regulation of apoptotic signaling pathway</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-47-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-47-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/18758450" target="_blank" title="PubMed ID 18758450" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=18758450">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0030307">involved_in positive regulation of cell growth</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-48-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-48-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/18625725" target="_blank" title="PubMed ID 18625725" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=18625725">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0030335">involved_in positive regulation of cell migration</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-49-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-49-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/19736306" target="_blank" title="PubMed ID 19736306" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=19736306">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0008284">involved_in positive regulation of cell population proliferation</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-50-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-50-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/14633705" target="_blank" title="PubMed ID 14633705" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=14633705">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0001938">involved_in positive regulation of endothelial cell proliferation</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-51-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-51-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0010718">involved_in positive regulation of epithelial to mesenchymal transition</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-52-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-52-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:1905007">involved_in positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-53-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-53-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:1901203">acts_upstream_of positive regulation of extracellular matrix assembly</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-54-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-54-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/28251559" target="_blank" title="PubMed ID 28251559" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=28251559">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0051491">involved_in positive regulation of filopodium assembly</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-55-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-55-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0010628">involved_in positive regulation of gene expression</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-56-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-56-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/27162619" target="_blank" title="PubMed ID 27162619" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=27162619">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0010628">involved_in positive regulation of gene expression</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-57-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-57-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:1902462">involved_in positive regulation of mesenchymal stem cell proliferation</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-58-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IGI</a>
<div id="evidence-code-58-1" class="ecode">Inferred from Genetic Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/22714950" target="_blank" title="PubMed ID 22714950" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=22714950">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0051897">involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-59-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-59-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/18625725" target="_blank" title="PubMed ID 18625725" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=18625725">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0051496">involved_in positive regulation of stress fiber assembly</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-60-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-60-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:1905075">involved_in positive regulation of tight junction disassembly</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-61-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-61-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:1904018">involved_in positive regulation of vasculature development</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-62-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-62-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/27693460" target="_blank" title="PubMed ID 27693460" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=27693460">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0009791">involved_in post-embryonic development</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-63-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-63-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0003342">NOT involved_in proepicardium development</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-64-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-64-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0006355">involved_in regulation of DNA-templated transcription</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-65-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-65-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/14517293" target="_blank" title="PubMed ID 14517293" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=14517293">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0006355">involved_in regulation of DNA-templated transcription</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-66-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-66-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/15702480" target="_blank" title="PubMed ID 15702480" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=15702480">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0060043">involved_in regulation of cardiac muscle cell proliferation</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-67-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-67-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0051726">involved_in regulation of cell cycle</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-68-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-68-1" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/9759503" target="_blank" title="PubMed ID 9759503" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=9759503">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0010717">involved_in regulation of epithelial to mesenchymal transition</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-69-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-69-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0010468">involved_in regulation of gene expression</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-70-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-70-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0031396">involved_in regulation of protein ubiquitination</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-71-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-71-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/18758450" target="_blank" title="PubMed ID 18758450" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=18758450">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0070723">involved_in response to cholesterol</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-72-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-72-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/17878231" target="_blank" title="PubMed ID 17878231" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=17878231">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0060021">involved_in roof of mouth development</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-73-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-73-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0007165">involved_in signal transduction</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-74-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-74-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/14633705" target="_blank" title="PubMed ID 14633705" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=14633705">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0001501">involved_in skeletal system development</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-75-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-75-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0048705">involved_in skeletal system morphogenesis</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-76-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-76-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0048538">involved_in thymus development</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-77-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-77-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0007179">involved_in transforming growth factor beta receptor signaling pathway</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-78-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-78-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0007179">involved_in transforming growth factor beta receptor signaling pathway</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-79-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IC</a>
<div id="evidence-code-79-1" class="ecode">Inferred by Curator<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/1326540" target="_blank" title="PubMed ID 1326540" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=1326540">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0007179">involved_in transforming growth factor beta receptor signaling pathway</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-80-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-80-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/1333888,9311995,9389648,11157754,12065756" target="_blank" title="PubMed ID 1333888,9311995,9389648,11157754,12065756" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=1333888,9311995,9389648,11157754,12065756">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0007179">involved_in transforming growth factor beta receptor signaling pathway</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-81-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IGI</a>
<div id="evidence-code-81-1" class="ecode">Inferred from Genetic Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/22714950" target="_blank" title="PubMed ID 22714950" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=22714950">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0007179">involved_in transforming growth factor beta receptor signaling pathway</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-82-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-82-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/1333888,24978044,27693460,28251559" target="_blank" title="PubMed ID 1333888,24978044,27693460,28251559" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=1333888,24978044,27693460,28251559">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0007179">involved_in transforming growth factor beta receptor signaling pathway</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-83-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-83-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0061450">involved_in trophoblast cell migration</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-84-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-84-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/34432647" target="_blank" title="PubMed ID 34432647" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=34432647">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0101023">involved_in vascular endothelial cell proliferation</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-85-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-85-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0003223">involved_in ventricular compact myocardium morphogenesis</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-86-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-86-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0060412">involved_in ventricular septum morphogenesis</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-87-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-87-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0003222">involved_in ventricular trabecula myocardium morphogenesis</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-88-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-88-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0042060">involved_in wound healing</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-89-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-89-1" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/9759503" target="_blank" title="PubMed ID 9759503" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=9759503">PubMed</a> </td>
</tr>
</tbody>
</table>
</div>
</div>
<div class="ui-ncbigrid-outer-div">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-config="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
<thead>
<tr>
<th class="col1">Component</th>
<th style="width:12%;">Evidence Code</th>
<th style="width:10%;">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0048179">part_of activin receptor complex</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-1-2" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005923">located_in bicellular tight junction</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-2-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/15761148" target="_blank" title="PubMed ID 15761148" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=15761148">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0009986">located_in cell surface</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-3-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/25893292" target="_blank" title="PubMed ID 25893292" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=25893292">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005929">located_in cilium</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-4-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005768">located_in endosome</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-5-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/26583432" target="_blank" title="PubMed ID 26583432" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=26583432">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0016020">located_in membrane</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-6-2" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0045121">located_in membrane raft</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-7-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/25893292" target="_blank" title="PubMed ID 25893292" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=25893292">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005654">located_in nucleoplasm</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-8-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-8-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005634">located_in nucleus</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-9-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-9-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/26583432" target="_blank" title="PubMed ID 26583432" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=26583432">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005886">is_active_in plasma membrane</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-10-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-10-2" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005886">located_in plasma membrane</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-11-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-11-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/17878231,21791611,25893292" target="_blank" title="PubMed ID 17878231,21791611,25893292" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=17878231,21791611,25893292">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005886">located_in plasma membrane</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-12-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> NAS</a>
<div id="evidence-code-12-2" class="ecode">Non-traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/18243111,20207738" target="_blank" title="PubMed ID 18243111,20207738" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=18243111,20207738">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005886">located_in plasma membrane</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-13-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-13-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0043235">part_of receptor complex</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-14-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-14-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/8774881,14517293" target="_blank" title="PubMed ID 8774881,14517293" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=8774881,14517293">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0070021">part_of transforming growth factor beta ligand-receptor complex</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-15-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
<div id="evidence-code-15-2" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/18243111,20207738" target="_blank" title="PubMed ID 18243111,20207738" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=18243111,20207738">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0070021">part_of transforming growth factor beta ligand-receptor complex</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-16-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-16-2" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
</div>
</div>
</div>
<div class="rprt-section gene-general-protein-info">
<section class="rprt-section-header" id="general-protein-info">
<h2 id="header-general-protein-info">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-protein-info .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">General protein information</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.General_Protein_Information" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<dl>
<dt>Preferred Names</dt>
<dd>TGF-beta receptor type-1</dd>
</dl>
<dl>
<dt>Names</dt>
<dd>activin A receptor type II-like kinase, 53kDa</dd>
<dd>activin A receptor type II-like protein kinase of 53kD</dd>
<dd>activin receptor-like kinase 5</dd>
<dd>mutant transforming growth factor beta receptor I</dd>
<dd>serine/threonine-protein kinase receptor R4</dd>
<dd>transforming growth factor beta receptor I</dd>
<dd>transforming growth factor-beta receptor type I</dd>
</dl>
<dl>
<dt class="heading">NP_001124388.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001293139.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394345.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394346.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394347.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394348.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394349.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394351.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394352.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394353.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394354.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394355.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394356.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394357.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394358.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394359.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394361.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394362.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394363.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394364.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394365.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394366.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_001394367.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_004603.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_011517250.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054219631.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.30">2.7.11.30</a></li>
</ul>
</dd>
</dl>
</div>
</div>
<div class="rprt-section gene-reference-sequences">
<section class="rprt-section-header" id="reference-sequences">
<h2 id="header-reference-sequences">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-reference-sequences .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">NCBI Reference Sequences (RefSeq)</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.NCBI_Reference_Sequences_RefS" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<p>
<span class="new-icon">NEW</span>
<strong>Try the new <a href="/datasets/tables/genes/?table_type=transcripts&amp;ids=7046&amp;utm_source=gene&amp;utm_medium=referral&amp;utm_campaign=refseq" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report." data-ga-category="refseq" data-ga-action="click_datasets_link" data-ga-label="transcript_table">Transcript table</a></strong>
</p>
<h3 class="genomerefseqs gene_std_toggler" id="refseqset-independent">
<a class="jig-ncbitoggler-open">RefSeqs maintained independently of Annotated
Genomes</a>
</h3>
<div class="genomerefseqs_slave">
<p class="desc"> These reference sequences exist independently of genome builds. <a href="#refseq-expl" id="expl-refseg">Explain</a></p>
<p id="refseq-expl"> These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in <a href="#geneGenomic regions, transcripts, and products">Genomic regions,
transcripts, and products</a> above. </p>
<h4 id="genomic-p103852528">Genomic </h4>
<ol>
<li>
<p>NG_007461.1 RefSeqGene</p>
<dl>
<dt>Range</dt>
<dd class="rs-range">
<span>4984..54063</span>
</dd>
<dt>Download</dt>
<dd><a href="/nuccore/NG_007461.1?from=4984&amp;to=54063&amp;report=genbank" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=NG_007461.1?from=4984&amp;to=54063&amp;report=genbank">GenBank</a>, <a href="/nuccore/NG_007461.1?from=4984&amp;to=54063&amp;report=fasta" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=NG_007461.1?from=4984&amp;to=54063&amp;report=fasta">FASTA</a>, <a href="/nuccore/NG_007461.1?from=1&amp;to=61424&amp;report=graph&amp;content=5" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=NG_007461.1?from=1&amp;to=61424&amp;report=graph&amp;content=5">Sequence Viewer (Graphics)</a></dd>
</dl>
</li>
</ol>
<h4 id="mrnaandproteins-p41402368">mRNA and Protein(s) </h4>
<ol>
<li>
<p><a href="/nuccore/NM_001130916.3">NM_001130916.3</a><a href="/protein/NP_001124388.1">NP_001124388.1</a>  TGF-beta receptor type-1 isoform 2 precursor</p>
<p>
<a href="/ipg/NP_001124388.1/" ref="ncbi_uid=7046">See identical proteins and their annotated locations for NP_001124388.1</a>
</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AJ619019, BC071181">AJ619019, BC071181</a>
</dd>
<dt>Consensus CDS</dt>
<dd>
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&amp;GO=MainBrowse&amp;DATA=CCDS47998.1">CCDS47998.1</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>
</dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000364129.2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">ENSP00000364129.2</a>, <a href="http://www.ensembl.org/id/ENST00000374990.6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">ENST00000374990.6</a></dd>
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001124388.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=271045">cd14143</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">132</span><span class="cddto">419</span></dt>
<dd class="clearfix"> STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=307282">pfam01064</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">35</span><span class="cddto">110</span></dt>
<dd class="clearfix"> Activin_recp; Activin types I and II receptor domain</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=312125">pfam08515</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">114</span><span class="cddto">126</span></dt>
<dd class="clearfix"> TGF_beta_GS; Transforming growth factor beta type I GS-motif</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001306210.2">NM_001306210.2</a><a href="/protein/NP_001293139.1">NP_001293139.1</a>  TGF-beta receptor type-1 isoform 3 precursor</p>
<p>
<a href="/ipg/NP_001293139.1/" ref="ncbi_uid=7046">See identical proteins and their annotated locations for NP_001293139.1</a>
</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AJ619019, AK302059">AJ619019, AK302059</a>
</dd>
<dt>Consensus CDS</dt>
<dd>
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&amp;GO=MainBrowse&amp;DATA=CCDS78413.1">CCDS78413.1</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>
</dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000447297.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">ENSP00000447297.1</a>, <a href="http://www.ensembl.org/id/ENST00000552516.5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">ENST00000552516.5</a></dd>
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001293139.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=271045">cd14143</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">213</span><span class="cddto">500</span></dt>
<dd class="clearfix"> STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=279413">pfam01064</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">35</span><span class="cddto">114</span></dt>
<dd class="clearfix"> Activin_recp; Activin types I and II receptor domain</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=285015">pfam07714</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">209</span><span class="cddto">496</span></dt>
<dd class="clearfix"> Pkinase_Tyr; Protein tyrosine kinase</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=285687">pfam08515</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">180</span><span class="cddto">207</span></dt>
<dd class="clearfix"> TGF_beta_GS; Transforming growth factor beta type I GS-motif</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407416.1">NM_001407416.1</a><a href="/protein/NP_001394345.1">NP_001394345.1</a>  TGF-beta receptor type-1 isoform 4 precursor</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0AAQ5BHT0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BHT0</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407417.1">NM_001407417.1</a><a href="/protein/NP_001394346.1">NP_001394346.1</a>  TGF-beta receptor type-1 isoform 5 precursor</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0AAQ5BHT0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BHT0</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407418.1">NM_001407418.1</a><a href="/protein/NP_001394347.1">NP_001394347.1</a>  TGF-beta receptor type-1 isoform 6</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A8V8TMH4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0A8V8TMH4</a>, <a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>, <a href="https://www.uniprot.org/uniprot/F8W0K6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">F8W0K6</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407419.1">NM_001407419.1</a><a href="/protein/NP_001394348.1">NP_001394348.1</a>  TGF-beta receptor type-1 isoform 6</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A8V8TMH4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0A8V8TMH4</a>, <a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>, <a href="https://www.uniprot.org/uniprot/F8W0K6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">F8W0K6</a></dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000514048.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">ENSP00000514048.1</a>, <a href="http://www.ensembl.org/id/ENST00000698941.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">ENST00000698941.1</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407420.1">NM_001407420.1</a><a href="/protein/NP_001394349.1">NP_001394349.1</a>  TGF-beta receptor type-1 isoform 6</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A8V8TMH4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0A8V8TMH4</a>, <a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>, <a href="https://www.uniprot.org/uniprot/F8W0K6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">F8W0K6</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407422.1">NM_001407422.1</a><a href="/protein/NP_001394351.1">NP_001394351.1</a>  TGF-beta receptor type-1 isoform 6</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A8V8TMH4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0A8V8TMH4</a>, <a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>, <a href="https://www.uniprot.org/uniprot/F8W0K6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">F8W0K6</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407423.1">NM_001407423.1</a><a href="/protein/NP_001394352.1">NP_001394352.1</a>  TGF-beta receptor type-1 isoform 7</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>, <a href="https://www.uniprot.org/uniprot/B4DY26" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">B4DY26</a>, <a href="https://www.uniprot.org/uniprot/F8VVC4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">F8VVC4</a>, <a href="https://www.uniprot.org/uniprot/H0YHS4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">H0YHS4</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407424.1">NM_001407424.1</a><a href="/protein/NP_001394353.1">NP_001394353.1</a>  TGF-beta receptor type-1 isoform 7</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>Consensus CDS</dt>
<dd>
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&amp;GO=MainBrowse&amp;DATA=CCDS94447.1">CCDS94447.1</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>, <a href="https://www.uniprot.org/uniprot/B4DY26" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">B4DY26</a>, <a href="https://www.uniprot.org/uniprot/F8VVC4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">F8VVC4</a>, <a href="https://www.uniprot.org/uniprot/H0YHS4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">H0YHS4</a></dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000449934.2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">ENSP00000449934.2</a>, <a href="http://www.ensembl.org/id/ENST00000547314.6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">ENST00000547314.6</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407425.1">NM_001407425.1</a><a href="/protein/NP_001394354.1">NP_001394354.1</a>  TGF-beta receptor type-1 isoform 7</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>, <a href="https://www.uniprot.org/uniprot/B4DY26" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">B4DY26</a>, <a href="https://www.uniprot.org/uniprot/F8VVC4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">F8VVC4</a>, <a href="https://www.uniprot.org/uniprot/H0YHS4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">H0YHS4</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407426.1">NM_001407426.1</a><a href="/protein/NP_001394355.1">NP_001394355.1</a>  TGF-beta receptor type-1 isoform 7</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>, <a href="https://www.uniprot.org/uniprot/B4DY26" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">B4DY26</a>, <a href="https://www.uniprot.org/uniprot/F8VVC4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">F8VVC4</a>, <a href="https://www.uniprot.org/uniprot/H0YHS4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">H0YHS4</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407427.1">NM_001407427.1</a><a href="/protein/NP_001394356.1">NP_001394356.1</a>  TGF-beta receptor type-1 isoform 7</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>, <a href="https://www.uniprot.org/uniprot/B4DY26" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">B4DY26</a>, <a href="https://www.uniprot.org/uniprot/F8VVC4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">F8VVC4</a>, <a href="https://www.uniprot.org/uniprot/H0YHS4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">H0YHS4</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407428.1">NM_001407428.1</a><a href="/protein/NP_001394357.1">NP_001394357.1</a>  TGF-beta receptor type-1 isoform 7</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>, <a href="https://www.uniprot.org/uniprot/B4DY26" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">B4DY26</a>, <a href="https://www.uniprot.org/uniprot/F8VVC4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">F8VVC4</a>, <a href="https://www.uniprot.org/uniprot/H0YHS4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">H0YHS4</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407429.1">NM_001407429.1</a><a href="/protein/NP_001394358.1">NP_001394358.1</a>  TGF-beta receptor type-1 isoform 7</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>, <a href="https://www.uniprot.org/uniprot/B4DY26" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">B4DY26</a>, <a href="https://www.uniprot.org/uniprot/F8VVC4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">F8VVC4</a>, <a href="https://www.uniprot.org/uniprot/H0YHS4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">H0YHS4</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407430.1">NM_001407430.1</a><a href="/protein/NP_001394359.1">NP_001394359.1</a>  TGF-beta receptor type-1 isoform 7</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>, <a href="https://www.uniprot.org/uniprot/B4DY26" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">B4DY26</a>, <a href="https://www.uniprot.org/uniprot/F8VVC4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">F8VVC4</a>, <a href="https://www.uniprot.org/uniprot/H0YHS4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">H0YHS4</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407432.1">NM_001407432.1</a><a href="/protein/NP_001394361.1">NP_001394361.1</a>  TGF-beta receptor type-1 isoform 7</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>, <a href="https://www.uniprot.org/uniprot/B4DY26" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">B4DY26</a>, <a href="https://www.uniprot.org/uniprot/F8VVC4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">F8VVC4</a>, <a href="https://www.uniprot.org/uniprot/H0YHS4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">H0YHS4</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407433.1">NM_001407433.1</a><a href="/protein/NP_001394362.1">NP_001394362.1</a>  TGF-beta receptor type-1 isoform 7</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>, <a href="https://www.uniprot.org/uniprot/B4DY26" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">B4DY26</a>, <a href="https://www.uniprot.org/uniprot/F8VVC4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">F8VVC4</a>, <a href="https://www.uniprot.org/uniprot/H0YHS4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">H0YHS4</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407434.1">NM_001407434.1</a><a href="/protein/NP_001394363.1">NP_001394363.1</a>  TGF-beta receptor type-1 isoform 7</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>, <a href="https://www.uniprot.org/uniprot/B4DY26" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">B4DY26</a>, <a href="https://www.uniprot.org/uniprot/F8VVC4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">F8VVC4</a>, <a href="https://www.uniprot.org/uniprot/H0YHS4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">H0YHS4</a></dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000447707.3" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">ENSP00000447707.3</a>, <a href="http://www.ensembl.org/id/ENST00000546584.2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">ENST00000546584.2</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407435.1">NM_001407435.1</a><a href="/protein/NP_001394364.1">NP_001394364.1</a>  TGF-beta receptor type-1 isoform 8 precursor</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407436.1">NM_001407436.1</a><a href="/protein/NP_001394365.1">NP_001394365.1</a>  TGF-beta receptor type-1 isoform 9</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407437.1">NM_001407437.1</a><a href="/protein/NP_001394366.1">NP_001394366.1</a>  TGF-beta receptor type-1 isoform 11 precursor</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_001407438.1">NM_001407438.1</a><a href="/protein/NP_001394367.1">NP_001394367.1</a>  TGF-beta receptor type-1 isoform 10 precursor</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/F8VXZ5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">F8VXZ5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_004612.4">NM_004612.4</a><a href="/protein/NP_004603.1">NP_004603.1</a>  TGF-beta receptor type-1 isoform 1 precursor</p>
<p>
<a href="/ipg/NP_004603.1/" ref="ncbi_uid=7046">See identical proteins and their annotated locations for NP_004603.1</a>
</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AJ619019, AK302059, L11695">AJ619019, AK302059, L11695</a>
</dd>
<dt>Consensus CDS</dt>
<dd>
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&amp;GO=MainBrowse&amp;DATA=CCDS6738.1">CCDS6738.1</a>
</dd>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/P36897" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">P36897</a>, <a href="https://www.uniprot.org/uniprot/Q6IR47" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">Q6IR47</a>, <a href="https://www.uniprot.org/uniprot/Q706C0" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">Q706C0</a>, <a href="https://www.uniprot.org/uniprot/Q706C1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">Q706C1</a></dd>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>, <a href="https://www.uniprot.org/uniprot/Q5T7S2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">Q5T7S2</a></dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000364133.4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">ENSP00000364133.4</a>, <a href="http://www.ensembl.org/id/ENST00000374994.9" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">ENST00000374994.9</a></dd>
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_004603.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=271045">cd14143</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">209</span><span class="cddto">496</span></dt>
<dd class="clearfix"> STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=279413">pfam01064</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">35</span><span class="cddto">114</span></dt>
<dd class="clearfix"> Activin_recp; Activin types I and II receptor domain</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=285015">pfam07714</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">205</span><span class="cddto">492</span></dt>
<dd class="clearfix"> Pkinase_Tyr; Protein tyrosine kinase</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=285687">pfam08515</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">176</span><span class="cddto">203</span></dt>
<dd class="clearfix"> TGF_beta_GS; Transforming growth factor beta type I GS-motif</dd>
</dl>
</dd>
</dl>
</li>
</ol>
<h4 id="rna-p31170960">RNA</h4>
<ol>
<li>
<p><a href="/nuccore/NR_176360.1">NR_176360.1</a> RNA Sequence </p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>Related</dt>
<dd>
<a href="http://www.ensembl.org/id/ENST00000714349.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">ENST00000714349.1</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NR_176361.1">NR_176361.1</a> RNA Sequence </p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>Related</dt>
<dd>
<a href="http://www.ensembl.org/id/ENST00000714351.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">ENST00000714351.1</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NR_176362.1">NR_176362.1</a> RNA Sequence </p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NR_176363.1">NR_176363.1</a> RNA Sequence </p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AL162427">AL162427</a>
</dd>
<dt>Related</dt>
<dd>
<a href="http://www.ensembl.org/id/ENST00000714347.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">ENST00000714347.1</a>
</dd>
</dl>
</li>
</ol>
</div>
<h3 class="genomerefseqs gene_std_toggler" id="annotatedrefseq-title">
<a class="jig-ncbitoggler-open">RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08</a>
</h3>
<div class="genomerefseqs_slave">
<p class="desc"> The following sections contain reference sequences that belong to a
specific genome build. <a href="#" id="expl-genomes">Explain</a></p>
<p id="expl-genomes-desc" style="display:none">This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.</p>
<h3 id="refseq-sequencedescription-p43969840">Reference GRCh38.p14 Primary Assembly</h3>
<h4 id="genomic-p43969840">Genomic </h4>
<ol>
<li>
<p>NC_000009.12 Reference GRCh38.p14 Primary Assembly</p>
<dl>
<dt>Range</dt>
<dd class="rs-range">
<span>99103647..99154192</span>
</dd>
<dt>Download</dt>
<dd><a href="/nuccore/NC_000009.12?from=99103647&amp;to=99154192&amp;report=genbank" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=NC_000009.12?from=99103647&amp;to=99154192&amp;report=genbank">GenBank</a>, <a href="/nuccore/NC_000009.12?from=99103647&amp;to=99154192&amp;report=fasta" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=NC_000009.12?from=99103647&amp;to=99154192&amp;report=fasta">FASTA</a>, <a href="/nuccore/NC_000009.12?from=99096064&amp;to=99161773&amp;report=graph&amp;content=5" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=NC_000009.12?from=99096064&amp;to=99161773&amp;report=graph&amp;content=5">Sequence Viewer (Graphics)</a></dd>
</dl>
</li>
</ol>
<h4 id="mrnaandproteins-p122472512">mRNA and Protein(s) </h4>
<ol>
<li>
<p><a href="/nuccore/XM_011518948.3">XM_011518948.3</a><a href="/protein/XP_011517250.1">XP_011517250.1</a>  TGF-beta receptor type-1 isoform X1</p>
<p>
<a href="/ipg/XP_011517250.1/" ref="ncbi_uid=7046">See identical proteins and their annotated locations for XP_011517250.1</a>
</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A8V8TMH4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0A8V8TMH4</a>, <a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>, <a href="https://www.uniprot.org/uniprot/F8W0K6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">F8W0K6</a></dd>
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011517250.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=271045">cd14143</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">144</span><span class="cddto">431</span></dt>
<dd class="clearfix"> STKc_TGFbR1_ACVR1b_ACVR1c; Catalytic domain of the Serine/Threonine Kinases, Transforming Growth Factor beta Type I Receptor and Activin Type IB/IC Receptors</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=395845">pfam01064</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">6</span><span class="cddto">41</span></dt>
<dd class="clearfix"> Activin_recp; Activin types I and II receptor domain</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=400699">pfam08515</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">111</span><span class="cddto">138</span></dt>
<dd class="clearfix"> TGF_beta_GS; Transforming growth factor beta type I GS-motif</dd>
</dl>
</dd>
</dl>
</li>
</ol>
<h3 id="refseq-sequencedescription-p134532736">Alternate T2T-CHM13v2.0</h3>
<h4 id="genomic-p134532736">Genomic </h4>
<ol>
<li>
<p>NC_060933.1 Alternate T2T-CHM13v2.0</p>
<dl>
<dt>Range</dt>
<dd class="rs-range">
<span>111275348..111325904</span>
</dd>
<dt>Download</dt>
<dd><a href="/nuccore/NC_060933.1?from=111275348&amp;to=111325904&amp;report=genbank" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=NC_060933.1?from=111275348&amp;to=111325904&amp;report=genbank">GenBank</a>, <a href="/nuccore/NC_060933.1?from=111275348&amp;to=111325904&amp;report=fasta" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=NC_060933.1?from=111275348&amp;to=111325904&amp;report=fasta">FASTA</a>, <a href="/nuccore/NC_060933.1?from=111267764&amp;to=111333486&amp;report=graph&amp;content=5" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=NC_060933.1?from=111267764&amp;to=111333486&amp;report=graph&amp;content=5">Sequence Viewer (Graphics)</a></dd>
</dl>
</li>
</ol>
<h4 id="mrnaandproteins-p102598720">mRNA and Protein(s) </h4>
<ol>
<li>
<p><a href="/nuccore/XM_054363656.1">XM_054363656.1</a><a href="/protein/XP_054219631.1">XP_054219631.1</a>  TGF-beta receptor type-1 isoform X1</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd><a href="https://www.uniprot.org/uniprot/A0A8V8TMH4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0A8V8TMH4</a>, <a href="https://www.uniprot.org/uniprot/A0AAQ5BI21" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">A0AAQ5BI21</a>, <a href="https://www.uniprot.org/uniprot/F8W0K6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=7046&amp;nlmid=&amp;db=gene">F8W0K6</a></dd>
</dl>
</li>
</ol>
</div>
</div>
</div>
<div class="rprt-section gene-related-sequences">
<section class="rprt-section-header" id="related-sequences">
<h2 id="header-related-sequences">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-related-sequences .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Related sequences</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Related_Sequences" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div>
<table id="proteinTblId" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/7046/data/related-sequences/',webserviceParams: 'p$l=Ajax', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
<thead>
<tr>
<th colspan="2" id="rs-nucleo">Nucleotide</th>
<th rowspan="2" id="rs-protein">Protein</th>
</tr>
<tr>
<th id="rs-heading">Heading</th>
<th id="rs-heading-acc">Accession and Version</th>
</tr>
</thead>
<tbody></tbody>
</table>
<table id="proteinTblId" class="jig-ncbigrid" data-jigconfig="isPageable:true, pageSize:25">
<thead>
<tr>
<th class="proteinTblTh" rowspan="2" id="rs-prot-acc">Protein Accession</th>
<th class="proteinTblTh" colspan="2" id="rs-link">Links</th>
</tr>
<tr>
<th id="rs-genepept">GenPept Link</th>
<th id="rs-uniprot">UniProtKB Link</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="rs-prot-acc">P36897.1</td>
<td headers="rs-link rs-genepept">
<a href="/protein/547777" ref="ordinalpos=1&amp;ncbi_uid=7046&amp;link_uid=547777">GenPept</a>
</td>
<td>
<a href="https://www.uniprot.org/uniprot/P36897">UniProtKB/Swiss-Prot:P36897</a>
</td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
<div class="rprt-section gene-additional-links">
<section class="rprt-section-header" id="additional-links"><h2 id="header-additional-links"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-additional-links .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Additional links</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Additional_Links" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
<div class="rprt-section-body" style="">
<h3 class="withnote" id="genelinkout">
<a class="jig-ncbitoggler">Gene LinkOut</a>
</h3><div>
<p>The following <a href="https://www.ncbi.nlm.nih.gov/projects/linkout/index.html">LinkOut</a> resources are supplied by external providers. These providers are responsible for maintaining the links. </p>
<div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Chemical Information</span>
</a>
<ul>
<li><span class="free-rsc"></span>Interologous Interaction Database</li>
<ul>
<li>
<a target="_blank" href="http://ophid.utoronto.ca/redirect/ncbi/human?proteins=7046" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7911">
<span>Interologous Interaction Database</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>MilliporeSigma</li>
<ul>
<li>
<a target="_blank" href="https://www.sigmaaldrich.com/catalog/genes/TGFBR1?lang=en&amp;region=US" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9978">
<span>Tgfbr1 products</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Medical</span>
</a>
<ul>
<li><span class="free-rsc"></span>MedlinePlus Health Information</li>
<ul>
<li>
<a target="_blank" href="https://medlineplus.gov/genetics/gene/tgfbr1" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=3162">
<span>TGFBR1 gene</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Molecular Biology Databases</span>
</a>
<ul>
<li><span class="free-rsc"></span>Bgee database</li>
<ul>
<li>
<a target="_blank" href="https://www.bgee.org/gene/ENSG00000106799" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10418">
<span>TGFBR1 gene expression</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>BioGPS</li>
<ul>
<li>
<a target="_blank" href="http://biogps.org/gene/7046/" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5059">
<span>BioGPS</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>BioGRID Open Repository of CRISPR Screens (ORCS)</li>
<ul>
<li>
<a target="_blank" href="https://orcs.thebiogrid.org/Gene/7046" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10164">
<span>BioGRID CRISPR Screen Phenotypes (67 hits/1394 screens)</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Domain Mapping of Disease Mutations</li>
<ul>
<li>
<a target="_blank" href="http://bioinf.umbc.edu/DMDM/gene_prot_page.php?id=7046" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7642">
<span>TGFBR1</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Eukaryotic Promoter Database</li>
<ul>
<li>
<a target="_blank" href="http://epd.vital-it.ch/cgi-bin/get_doc?db=hgEpdNew&amp;format=genome&amp;entry=TGFBR1_1" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9624">
<span>TGFBR1_1</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>GlyGen glycoinformatics resource</li>
<ul>
<li>
<a target="_blank" href="https://glygen.org/protein/P36897" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10227">
<span>GlyGen glycoinformatics resource</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Guide to Pharmacology</li>
<ul>
<li>
<a target="_blank" href="https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1788" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8191">
<span>transforming growth factor beta receptor 1 gene</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span><span class="regis-rsc"></span>Human Gene Mutation Database</li>
<ul>
<li>
<a target="_blank" href="http://www.hgmd.cf.ac.uk/ac/gene.php?gene=TGFBR1" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=3100">
<span>Human Gene Mutation Database</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Human eFP Browser</li>
<ul>
<li>
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Circulatory_Respiratory&amp;modeInput=Absolute&amp;primaryGene=7046" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8875">
<span>Human eFP Browser</span>
</a>
</li>
<li>
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Skeletal_Immune_Digestive&amp;modeInput=Absolute&amp;primaryGene=7046" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8875">
<span>Human eFP Browser</span>
</a>
</li>
<li>
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Reproductive&amp;modeInput=Absolute&amp;primaryGene=7046" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8875">
<span>Human eFP Browser</span>
</a>
</li>
</ul>
<li>Ingenuity Pathways Analysis</li>
<ul>
<li>
<a target="_blank" href="http://partnersolution.ingenuity.com/?cid=97ae3f91eab87a&amp;p1=Entrez&amp;p2=GV&amp;s=&amp;ipaUri=%2Fpa%2Fapi%2Fv2%2Fgeneview%3Fapplicationname%3DEntrez%26geneId%3D7046%26geneidtype%3Dentrezgene" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5628">
<span>Ingenuity Pathways Analysis</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>InnateDB</li>
<ul>
<li>
<a target="_blank" href="http://www.innatedb.com/getGeneCard.do?id=78488" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7894">
<span>InnateDB</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>InterMine</li>
<ul>
<li>
<a target="_blank" href="https://www.humanmine.org/humanmine/search?keyword=ENSG00000106799" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9169">
<span>InterMine</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Kyoto Encyclopedia of Genes and Genomes</li>
<ul>
<li>
<a target="_blank" href="http://www.genome.jp/dbget-bin/www_bget?hsa:7046" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5174">
<span>Kyoto Encyclopedia of Genes and Genomes</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>OMA Browser: Orthologous MAtrix</li>
<ul>
<li>
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN97801/" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9822">
<span>OMA Browser: Orthologous MAtrix</span>
</a>
</li>
<li>
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN97795/" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9822">
<span>OMA Browser: Orthologous MAtrix</span>
</a>
</li>
<li>
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN97796/" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9822">
<span>OMA Browser: Orthologous MAtrix</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>OrthoDB catalog of orthologs</li>
<ul>
<li>
<a target="_blank" href="https://www.orthodb.org/?ncbi=7046" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8178">
<span>Orthologs</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Pharmacogenomics Knowledge Base</li>
<ul>
<li>
<a target="_blank" href="https://www.pharmgkb.org/gene/PA36485" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=4067">
<span>Annotated Pharmacogenomic Information for TGFBR1 [PharmGKB]</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>PhosphoSitePlus</li>
<ul>
<li>
<a target="_blank" href="https://www.phosphosite.org/entrezGeneIdAction.action?id=7046" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7987">
<span>PhosphoSitePlus® - comprehensive post-translational modification resource</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>The Gene Wiki</li>
<ul>
<li>
<a target="_blank" href="https://en.wikipedia.org/wiki/TGF_beta_receptor_1" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=6933">
<span>The Gene Wiki</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>The Weizmann Institute of Science GeneCards and MalaCards databases</li>
<ul>
<li>
<a target="_blank" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=TGFBR1" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8598">
<span>GeneCard for TGFBR1</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Research Materials</span>
</a>
<ul>
<li><span class="order-rsc"></span>Addgene Non-profit plasmid repository</li>
<ul>
<li>
<a target="_blank" href="https://addgene.org//browse/gene/7046" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5304">
<span>Get Plasmids - Addgene</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>Bio-Techne</li>
<ul>
<li>
<a target="_blank" href="https://www.bio-techne.com/t/tgf-beta-ri-alk-5/proteins-enzymes?utm_source=linkout&amp;utm_medium=referral&amp;utm_campaign=product&amp;utm_term=proteins" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8242">
<span>TGF-beta RI/ALK-5 Proteins</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.bio-techne.com/t/tgf-beta-ri-alk-5/antibodies?utm_source=linkout&amp;utm_medium=referral&amp;utm_campaign=product&amp;utm_term=antibodies" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8242">
<span>TGF-beta RI/ALK-5 Antibodies</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.bio-techne.com/t/tgf-beta-ri-alk-5/lysates?utm_source=linkout&amp;utm_medium=referral&amp;utm_campaign=product&amp;utm_term=lysates" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8242">
<span>TGF-beta RI/ALK-5 Lysates</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>Creative Biogene</li>
<ul>
<li>
<a target="_blank" href="https://www.creative-biogene.com/genesearch/TGFBR1.html" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10094">
<span>transforming growth factor, beta receptor 1</span>
</a>
</li>
</ul>
<li>ExactAntigen/Labome</li>
<ul>
<li>
<a target="_blank" href="https://www.labome.com/review/gene/human/TGFBR1-antibody.html" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5753">
<span>reagent review</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.labome.com/gene/human/TGFBR1-antibody.html" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5753">
<span>reagents</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>GenScript latest version of gene cDNA ORF Clone</li>
<ul>
<li>
<a target="_blank" href="http://www.genscript.com/gene/7046" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8012">
<span>GenScript latest version of gene cDNA ORF Clone</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>GeneCopoeia Inc.</li>
<ul>
<li>
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=11&amp;field=5&amp;key=7046" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7255">
<span>Order shRNA clones</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=1&amp;field=5&amp;key=7046" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7255">
<span>Order full-length ORF clone</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?tax_id=9606&amp;field=5&amp;prt=16&amp;key=7046" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7255">
<span>Order miRNA target clones</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>Kazusa DNA Research Institute</li>
<ul>
<li>
<a target="_blank" href="http://www.kazusa.or.jp/kop/dsearch/symsearch.cgi?keyword=TGFBR1;" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=3267">
<span>Kazusa DNA Research Institute</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>OriGene</li>
<ul>
<li>
<a target="_blank" href="https://www.origene.com/search?q=Tgfbr1" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7994">
<span>Order Tgfbr1 cDNA clone/Protein/Antibody/RNAi</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Tools</span>
</a>
<ul>
<li><span class="free-rsc"></span>GeneMANIA</li>
<ul>
<li>
<a target="_blank" href="http://genemania.org/link?o=9606&amp;g=7046" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7529">
<span>GeneMANIA</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open">
<span>Miscellaneous</span>
</a>
<ul>
<li><span class="free-rsc"></span>Reactome</li>
<ul>
<li>
<a target="_blank" href="https://reactome.org/PathwayBrowser/#/R-HSA-1643685" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=4914">
<span>Reactome Event:Disease</span>
</a>
</li>
<li>
<a target="_blank" href="https://reactome.org/PathwayBrowser/#/R-HSA-162582" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=4914">
<span>Reactome Event:Signal Transduction</span>
</a>
</li>
<li>
<a target="_blank" href="https://reactome.org/content/query?q=UniProt:P36897" ref="itool=Gene_FullReport&amp;uid=7046&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=4914">
<span>Reactome Entity:P36897</span>
</a>
</li>
</ul>
</ul>
</div>
</div>
</div>
<div id="urls-in-genombrowser" style="display:none">
</div>
</div>
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</div>
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<!-- sidebar close/hide button-->
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<h2 class="offscreen_noflow">Supplemental Content</h2>
<div id="gene-sidebar">
<div>
<div class="portlet brieflink dis-table-of-contents">
<div class="portlet_head">
<div class="portlet_title">
<h3>Table of contents</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_TableOfContents" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter"></a>
</div>
<div class="portlet_content">
<ul>
<li class="">
<a href="#summary">Summary</a>
</li>
<li class="">
<a href="#genomic-context">Genomic context</a>
</li>
<li class="">
<a href="#genomic-regions-transcripts-products">Genomic regions, transcripts, and products</a>
</li>
<li class="">
<a href="#gene-expression">Expression</a>
</li>
<li class="">
<a href="#bibliography">Bibliography</a>
</li>
<li class="">
<a href="#phenotypes">Phenotypes</a>
</li>
<li class="">
<a href="#variation">Variation</a>
</li>
<li class="">
<a href="#HIV-1-interactions">HIV-1 interactions</a>
</li>
<li class="">
<a href="#pathways">Pathways from PubChem</a>
</li>
<li class="">
<a href="#interactions">Interactions</a>
</li>
<li class="">
<a href="#general-gene-info">General gene information</a>
<div class="subsection-links"><a href="#gene-markers">Markers</a>, <a href="#Relatedpseudogenes">Related pseudogene(s)</a>, <a href="#homology">Homology</a>, <a href="#gene-ontology">Gene Ontology</a></div>
</li>
<li class="">
<a href="#general-protein-info">General protein information</a>
</li>
<li class="">
<a href="#reference-sequences">NCBI Reference Sequences (RefSeq)</a>
</li>
<li class="">
<a href="#related-sequences">Related sequences</a>
</li>
<li class="">
<a href="#additional-links">Additional links</a>
</li>
</ul>
</div>
</div>
<div class="portlet brieflink dis-genomesbrowser brieflink dis-genomesbrowser">
<div class="portlet_head">
<div class="portlet_title">
<h3>Genome Browsers</h3>
</div>
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<li>
<a href="#">Loading...</a>
</li>
</ul>
</div>
</div>
<div class="portlet dis-related-info brieflink">
<div class="portlet_head">
<div class="portlet_title">
<h3>Related information</h3>
</div>
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</div>
<div class="portlet_content DiscoveryDbLinks">
<ul>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/clone/order/gene/7046" ref="log$=recordlinks">Order cDNA clone</a>
<div class="brieflinkpop offscreen_noflow">Order cDNA clone</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/structure?LinkName=gene_structure&amp;from_uid=7046" ref="log$=recordlinks">3D structures</a>
<div class="brieflinkpop offscreen_noflow">3D structure of a gene</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_alltarget_list&amp;from_uid=7046" ref="log$=recordlinks">BioAssay by Target (List)</a>
<div class="brieflinkpop offscreen_noflow">BioAssays related to the gene by protein target or RNAi target</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="//pubchem.ncbi.nlm.nih.gov/assay/bioactivity.html?geneid=7046" ref="log$=recordlinks">BioAssay by Target (Summary)</a>
<div class="brieflinkpop offscreen_noflow">Summarized PubChem Data on the gene, showing the active data by default</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_target&amp;from_uid=7046" ref="log$=recordlinks">BioAssay, by Gene target</a>
<div class="brieflinkpop offscreen_noflow">PubChem BioAssays done on the Gene target</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_rnai&amp;from_uid=7046" ref="log$=recordlinks">BioAssays, RNAi Target, Tested</a>
<div class="brieflinkpop offscreen_noflow">BioAssays that contain the gene as the target of a RNAi reagent</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/bioproject?LinkName=gene_bioproject&amp;from_uid=7046" ref="log$=recordlinks">BioProjects</a>
<div class="brieflinkpop offscreen_noflow">BioProjects related to a gene</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/biosystems?LinkName=gene_biosystems&amp;from_uid=7046" ref="log$=recordlinks">BioSystems</a>
<div class="brieflinkpop offscreen_noflow">BioSystems</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/books?LinkName=gene_books&amp;from_uid=7046" ref="log$=recordlinks">Books</a>
<div class="brieflinkpop offscreen_noflow">Books</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/CCDS/CcdsBrowse.cgi?REQUEST=GENEID&amp;DATA=7046" ref="log$=recordlinks">CCDS</a>
<div class="brieflinkpop offscreen_noflow">Link to CCDS</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar&amp;from_uid=7046" ref="log$=recordlinks">ClinVar</a>
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/cdd?LinkName=gene_cdd&amp;from_uid=7046" ref="log$=recordlinks">Conserved Domains</a>
<div class="brieflinkpop offscreen_noflow">Related CDD</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/dbvar?LinkName=gene_dbvar&amp;from_uid=7046" ref="log$=recordlinks">dbVar</a>
<div class="brieflinkpop offscreen_noflow">Link from Gene to dbVar</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc&amp;from_uid=7046" ref="log$=recordlinks">Full text in PMC</a>
<div class="brieflinkpop offscreen_noflow">PMC links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc_nucleotide&amp;from_uid=7046" ref="log$=recordlinks">Full text in PMC_nucleotide</a>
<div class="brieflinkpop offscreen_noflow">Full text in PubMedCentral identified from shared sequence links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/sparcle?LinkName=gene_sparcle&amp;from_uid=7046" ref="log$=recordlinks">Functional Class</a>
<div class="brieflinkpop offscreen_noflow">Functional class of the sequence domain architecture</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gap?LinkName=gene_gap&amp;from_uid=7046" ref="log$=recordlinks">GAP</a>
<div class="brieflinkpop offscreen_noflow">GAP Links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_neighbors&amp;from_uid=7046" ref="log$=recordlinks">Gene neighbors</a>
<div class="brieflinkpop offscreen_noflow">Overlapping genes and two nearest non-overlapping genes on either side</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/genome?LinkName=gene_genome&amp;from_uid=7046" ref="log$=recordlinks">Genome</a>
<div class="brieflinkpop offscreen_noflow">Related Genome</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/geoprofiles?LinkName=gene_geoprofiles&amp;from_uid=7046" ref="log$=recordlinks">GEO Profiles</a>
<div class="brieflinkpop offscreen_noflow">Related GEO</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gtr/tests/?term=7046[geneid]" ref="log$=recordlinks">GTR</a>
<div class="brieflinkpop offscreen_noflow">Tests for this gene in the NIH Genetic Testing Registry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/homologene?LinkName=gene_homologene&amp;from_uid=7046" ref="log$=recordlinks">HomoloGene</a>
<div class="brieflinkpop offscreen_noflow">Related HomoloGene</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/medgen?LinkName=gene_medgen_diseases&amp;from_uid=7046" ref="log$=recordlinks">MedGen</a>
<div class="brieflinkpop offscreen_noflow">Related information in MedGen</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore&amp;from_uid=7046" ref="log$=recordlinks">Nucleotide</a>
<div class="brieflinkpop offscreen_noflow">Link to related Nucleotide entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/omim?LinkName=gene_omim&amp;from_uid=7046" ref="log$=recordlinks">OMIM</a>
<div class="brieflinkpop offscreen_noflow">Link to related OMIM entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/probe?LinkName=gene_probe&amp;from_uid=7046" ref="log$=recordlinks">Probe</a>
<div class="brieflinkpop offscreen_noflow">Related Probe entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein&amp;from_uid=7046" ref="log$=recordlinks">Protein</a>
<div class="brieflinkpop offscreen_noflow">Link to related protein entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pccompound?LinkName=gene_pccompound&amp;from_uid=7046" ref="log$=recordlinks">PubChem Compound</a>
<div class="brieflinkpop offscreen_noflow">PubChem Compounds</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcsubstance?LinkName=gene_pcsubstance&amp;from_uid=7046" ref="log$=recordlinks">PubChem Substance</a>
<div class="brieflinkpop offscreen_noflow">PubChem Substances</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed&amp;from_uid=7046" ref="log$=recordlinks">PubMed</a>
<div class="brieflinkpop offscreen_noflow">Link to related PubMed entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_rif&amp;from_uid=7046" ref="log$=recordlinks">PubMed (GeneRIF)</a>
<div class="brieflinkpop offscreen_noflow">Link to related PubMed article from GeneRIFs</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_citedinomim&amp;from_uid=7046" ref="log$=recordlinks">PubMed (OMIM)</a>
<div class="brieflinkpop offscreen_noflow">Gene links to PubMed derived from omim_pubmed_cited links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_pmc_nucleotide&amp;from_uid=7046" ref="log$=recordlinks">PubMed(nucleotide/PMC)</a>
<div class="brieflinkpop offscreen_noflow">Citations in PubMed identified from shared sequence and PMC links.</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein_refseq&amp;from_uid=7046" ref="log$=recordlinks">RefSeq Proteins</a>
<div class="brieflinkpop offscreen_noflow">Link to Protein RefSeqs</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore_refseqrna&amp;from_uid=7046" ref="log$=recordlinks">RefSeq RNAs</a>
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeq RNAs</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/nuccore/170014713?report=graph" ref="log$=recordlinks">RefSeqGene</a>
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeqGenes</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar_specific&amp;from_uid=7046" ref="log$=recordlinks">Related gene-specific medical variations</a>
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/snp?LinkName=gene_snp&amp;from_uid=7046" ref="log$=recordlinks">SNP</a>
<div class="brieflinkpop offscreen_noflow">Related SNP records</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/taxonomy?LinkName=gene_taxonomy&amp;from_uid=7046" ref="log$=recordlinks">Taxonomy</a>
<div class="brieflinkpop offscreen_noflow">Link to related taxonomy entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/variation/view/?q=7046[geneid]" ref="log$=recordlinks">Variation Viewer</a>
<div class="brieflinkpop offscreen_noflow">Related Variants</div>
</li>
</ul>
</div>
</div>
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<div class="portlet_head">
<div class="portlet_title">
<h3>Links to other resources</h3>
</div>
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<div class="portlet_content">
<ul>
<li>
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11772">HGNC</a>
</li>
<li>
<a href="http://www.ensembl.org/id/ENSG00000106799">Ensembl</a>
</li>
<li>
<a href="https://www.alliancegenome.org/gene/HGNC:11772">AllianceGenome</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=geneid&amp;org=9606&amp;l=7046">AceView</a>
</li>
<li>
<a href="http://www.sanger.ac.uk/perl/genetics/CGP/cosmic?action=gene&amp;ln=TGFBR1">Catalogue of Somatic Mutations in Cancer (COSMIC)</a>
</li>
<li>
<a href="https://databases.lovd.nl/shared/genes/TGFBR1">TGFBR1 database</a>
</li>
<li>
<a href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&amp;position=NM_001407420">UCSC</a>
</li>
<li>
<a href="https://genecollections.nci.nih.gov/MGC/?ORG=Hs&amp;LIST=BC071181">MGC</a>
</li>
<li>
<a href="https://phgkb.cdc.gov/PHGKB/huGEPedia.action?firstQuery=TGFBR1&amp;geneID=7046&amp;typeOption=gene&amp;which=2&amp;pubOrderType=pubD&amp;typeSubmit=GO&amp;check=y">HuGE Navigator</a>
</li>
<li>
<a href="http://www.genome.jp/dbget-bin/www_bget?hsa:7046">KEGG</a>
</li>
<li>
<a href="https://reactome.org/content/query?q=UniProt:P36897">Reactome</a>
</li>
</ul>
</div>
</div>
<div class="portlet brieflink dis-general-info">
<div class="portlet_head">
<div class="portlet_title">
<h3>General information</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_GeneralInfo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter"></a>
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<div class="portlet_content">
<ul>
<li>
<a href="/pmc/?term=PMC4383897+OR+PMC3013746+OR+PMC1761442+OR+PMC539985">About Gene</a>
</li>
<li>
<a href="/books/NBK3840">FAQ</a>
</li>
<li>
<a href="https://ftp.ncbi.nlm.nih.gov/gene/">FTP site</a>
</li>
<li>
<a href="/books/NBK3841/">Help</a>
</li>
<li>
<a href="/books/NBK3842/">My NCBI help</a>
</li>
<li>
<a href="/books/NBK21085/">NCBI Handbook</a>
</li>
<li>
<a href="/gene/statistics/">Statistics</a>
</li>
</ul>
</div>
</div>
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<div class="portlet_head">
<div class="portlet_title">
<h3>Related sites</h3>
</div>
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<a href="https://www.ncbi.nlm.nih.gov/BLAST">BLAST</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/genome">Genome</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/bioproject">BioProject</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/genome/gdv/">Genome Data Viewer</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/geo">GEO</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/omim">OMIM</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/probe">Probe</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/RefSeq">RefSeq</a>
</li>
</ul>
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<a href="https://support.ncbi.nlm.nih.gov/ics/support/ticketnewwizard.asp?style=classic&amp;deptID=28049">Contact Help Desk</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/RefSeq/update.cgi?geneid=7046&amp;symbol=TGFBR1">Submit Correction</a>
</li>
<li>
<a href="/gene/submit-generif?geneId=7046&amp;sym=TGFBR1&amp;name=transforming growth factor beta receptor 1&amp;org=Homo sapiens">Submit GeneRIF</a>
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<a href="https://www.ncbi.nlm.nih.gov/mailman/listinfo/refseq-announce">RefSeq</a>
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<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67d68c5484f3725e59a99572">TGFBR1 transforming growth factor beta receptor 1 [Homo sapiens]</a>
<div class="ralinkpop offscreen_noflow">TGFBR1 transforming growth factor beta receptor 1 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:7046</div></div>
<div class="tertiary">Gene</div>
</li>
<li class="ra_rcd ralinkpopper two_line">
<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=2" href="/portal/utils/pageresolver.fcgi?recordid=67d68c5267c23b31e0310bb9">Loeys Dietz Aortic Aneurysm Syndrome</a>
<div class="ralinkpop offscreen_noflow">Loeys Dietz Aortic Aneurysm Syndrome<div class="brieflinkpopdesc"></div></div>
<div class="tertiary">MedGen</div>
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<li class="ra_qry two_line">
<a class="htb" ref="log$=activity&amp;linkpos=3" href="/portal/utils/pageresolver.fcgi?recordid=67d68c512f30673f7b774634">C1836635[conceptid] <span class="number">(1)</span></a>
<div class="tertiary">MedGen</div>
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<li class="ra_qry ralinkpopper two_line">
<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=4" href="/portal/utils/pageresolver.fcgi?recordid=67d68c4c84f3725e59a97a7b">(("clinical guidelines"[Resource Type]) OR "practice guideline"[P... <span class="number">(4)</span></a>
<div class="ralinkpop offscreen_noflow">(("clinical guidelines"[Resource Type]) OR "practice guideline"[Publication Type]) AND ("Loeys Dietz Aortic Aneurysm Syndrome")<div class="brieflinkpopdesc">Search</div></div>
<div class="tertiary">Books</div>
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<li class="ra_rcd ralinkpopper two_line">
<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=5" href="/portal/utils/pageresolver.fcgi?recordid=67d68c1084f3725e59a88b31">TP53 tumor protein p53 [Homo sapiens]</a>
<div class="ralinkpop offscreen_noflow">TP53 tumor protein p53 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:7157</div></div>
<div class="tertiary">Gene</div>
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