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4222 lines
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327 KiB
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<h1 class="res_name"><a href="/gene/">Gene</a></h1>
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<h2 class="res_tagline">Genes and mapped phenotypes</h2>
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<div class="search"><div class="search_form"><label for="database" class="offscreen_noflow">Search database</label><select id="database"><optgroup label="Recent"><option value="pubmed">PubMed</option><option value="clinvar">ClinVar</option><option value="medgen">MedGen</option><option value="books" class="last">Books</option></optgroup><optgroup label="All"><option value="gquery">All Databases</option><option value="assembly" data-ac_dict="assembly">Assembly</option><option value="biocollections">Biocollections</option><option value="bioproject">BioProject</option><option value="biosample">BioSample</option><option value="books">Books</option><option value="clinvar">ClinVar</option><option value="cdd">Conserved Domains</option><option value="gap">dbGaP</option><option value="dbvar">dbVar</option><option value="gene" selected="selected" data-ac_dict="gene">Gene</option><option value="genome" data-ac_dict="genome">Genome</option><option value="gds">GEO DataSets</option><option value="geoprofiles">GEO Profiles</option><option value="gtr">GTR</option><option value="ipg">Identical Protein Groups</option><option value="medgen">MedGen</option><option value="mesh">MeSH</option><option value="nlmcatalog">NLM Catalog</option><option value="nuccore" data-ac_dict="nuccore">Nucleotide</option><option value="omim">OMIM</option><option value="pmc">PMC</option><option value="protein" data-ac_dict="protein">Protein</option><option value="proteinclusters">Protein Clusters</option><option value="protfam">Protein Family Models</option><option value="pcassay">PubChem BioAssay</option><option value="pccompound">PubChem Compound</option><option value="pcsubstance">PubChem Substance</option><option value="pubmed">PubMed</option><option value="snp">SNP</option><option value="sra">SRA</option><option value="structure">Structure</option><option value="taxonomy">Taxonomy</option><option value="toolkit">ToolKit</option><option value="toolkitall">ToolKitAll</option><option value="toolkitbookgh">ToolKitBookgh</option></optgroup></select><div class="nowrap"><label for="term" class="offscreen_noflow" accesskey="/">Search term</label><div class="nowrap"><input type="text" name="term" id="term" title="Search Gene. Use up and down arrows to choose an item from the autocomplete." value="" class="jig-ncbiclearbutton jig-ncbiautocomplete" data-jigconfig="dictionary:'gene',disableUrl:'NcbiSearchBarAutoComplCtrl'" autocomplete="off" data-sbconfig="ds:'no',pjs:'yes',afs:'yes'" /></div><button id="search" type="submit" class="button_search nowrap" cmd="go">Search</button></div></div><ul class="searchlinks inline_list"><set></set><li><a href="/gene/advanced">Advanced</a></li><li class="help"><a id="help" class="jig-ncbihelpwindow" target="ncbihelp" name="help" href="/books/NBK3841/">Help</a></li></ul></div>
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<input name="EntrezSystem2.PEntrez.Gene.Gene_PageController.PreviousPageName" sid="1" type="hidden" value="results" />
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<h2 class="offscreen_noflow">Result Filters</h2>
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<div class="facet_cont" data-db="gene" data-default_grps="fg_gene-sources,fg_categories,fg_sequence-content,fg_status" data-sd="db:'gene',op:'select',term:'',qk:'2894',linkname:'',idsfromresult:'4261',extra:''"><ul class="facet" data-filter_id="gene-sources" id="_gene-sources"><li class="filter_grp "><div class="clearfix"><h3>Gene sources</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="genomic">Genomic</a></li></ul></li></ul><ul class="facet" data-filter_id="categories" id="_categories"><li class="filter_grp "><div class="clearfix"><h3>Categories</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="alt-splicing">Alternatively spliced</a></li><li class="fil_val"><a href="#" data-value_id="annotated-genes">Annotated genes</a></li><li class="fil_val"><a href="#" data-value_id="gene-type-protein-coding">Protein-coding</a></li></ul></li></ul><ul class="facet" data-filter_id="sequence-content" id="_sequence-content"><li class="filter_grp "><div class="clearfix"><h3>Sequence content</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="seq-ccds">CCDS</a></li><li class="fil_val"><a href="#" data-value_id="seq-ensembl">Ensembl</a></li><li class="fil_val"><a href="#" data-value_id="refseq">RefSeq</a></li><li class="fil_val"><a href="#" data-value_id="seq-refseqgene">RefSeqGene</a></li></ul></li></ul><ul class="facet" data-filter_id="status" id="_status"><li class="filter_grp "><div class="clearfix"><h3>Status</h3><a href="#" data-value_id="" class="clear clear_show">Clear</a></div><ul><li class="fil_val selected"><a href="#" data-value_id="current-only">Current</a><span class="fcount">(1)</span></li></ul></li></ul><div id="chr-location-facet-wrapper" data-bid="MCID_67c9da53d74f6769103f27b5" data-hid="MCID_67c90f2d64f30b25346ccae2" data-qky="2894" class="disabled" style="display:none"><ul class="facet" data-filter_id="chromosomal-region" id="_chromosomal-region" data-of="yes"><li class="filter_grp of_grp"><div class="clearfix"><h3>Chromosome locations</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><a id="facet_ofchromosomal-region" href="#facet_of_divchromosomal-region" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'middle left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '375px'" data-value_id="fetch_more">more...</a><div id="facet_of_divchromosomal-region" style="display:none;" class="of_popup"><h4>Chromosome locations</h4><label for="organism-filter" style="width:100%;margin-bottom:.2em;" class="">Select an organism by typing or scrolling</label><input type="text" placeholder="Enter text to narrow down the list" id="organism-filter" style="width:98%;" autocomplete="off" /><br /><div id="chr-region-tax-list"><select id="of_chromosomal-region" size="9" class="chr-region-tax-list" style="width:100%;"></select></div><div id="chr-location-info-ctrl" data-disabled="disabled"><div class="chr-field"><label for="chr-name">Chromosome</label><br /><select id="chr-name" class="chr-field" disabled="disabled"></select></div><div class="chr-field"><label for="chr-from">From</label><br /><input type="text" name="chr-from" id="chr-from" disabled="disabled" class="chr-field" /></div><div class="chr-field"><label for="chr-to">To</label><br /><input type="text" name="chr-to" id="chr-to" disabled="disabled" class="chr-field" /></div></div><div class="actions clearfix"><button class="jig-ncbibutton of_add apply-chr" data-jigconfig="'color': 'ui-ncbibutton-blue'">Apply</button></div></div></ul></li></ul></div><ul class="facet facet_reset"><li><a href="#" data-value_id="reset">Clear all</a></li></ul><ul class="facet_tools"><li><a id="more_filter_groups_link" href="#more_filter_groups" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'top left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '180px'">
|
||
Show additional filters</a></li><div id="more_filter_groups" style="display:none;" class="facets_dialog"><button class="ui-ncbipopper-close-button ui-ncbipopper-close-button-generated ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-blue" generated="true" role="button" aria-disabled="false"><span class="ui-button-text">x</span></button><h4>Additional filters</h4><ul class="filter_groups_more facet"><li><input type="checkbox" id="fg_gene-sources" /><label for="fg_gene-sources">Gene sources</label></li><li><input type="checkbox" id="fg_categories" /><label for="fg_categories">Categories</label></li><li><input type="checkbox" id="fg_sequence-content" /><label for="fg_sequence-content">Sequence content</label></li><li><input type="checkbox" id="fg_status" /><label for="fg_status">Status</label></li><li><input type="checkbox" id="fg_chromosomal-region" /><label for="fg_chromosomal-region">Chromosome locations</label></li><li><input id="fg_field_search" type="checkbox" /><label for="fg_field_search">Search fields</label></li></ul><div class="actions clearfix"><button class="filter_groups_more_apply jig-ncbibutton primary-action" id="filter_groups_apply" data-jigconfig="'color': 'ui-ncbibutton-blue'">Show</button></div></div></ul><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetsUrlFrag" sid="1" type="hidden" value="filters=current-only" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetSubmitted" sid="1" type="hidden" value="false" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.BMFacets" sid="1" type="hidden" value="" /></div>
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|
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<span style="display: block; text-align: center;">S</span>
|
||
<span style="display: block; text-align: center;">I</span>
|
||
<span style="display: block; text-align: center;">D</span>
|
||
<span style="display: block; text-align: center;">E</span>
|
||
<span style="display: block; text-align: center;">B</span>
|
||
<span style="display: block; text-align: center;">A</span>
|
||
<span style="display: block; text-align: center;">R</span>
|
||
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<div class="results_settings one_setting"><ul class="inline_list left display_settings"><li><a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Display" sid="0" href="#" class="jig-ncbipopper" data-jigconfig="triggerPosition : 'bottom center',destPosition : 'top center',destSelector : '#display_settings_menu_report', hasArrow : false,openEvent : 'click',closeEvent : 'click',isTriggerElementCloseClick: false,addCloseButton : false, groupName: 'entrez_pg'" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Display">Full Report<span href="#" class="tgt_dark"></span></a></li></ul><div id="display_settings_menu_report" class="disp_settings tabPopper"><fieldset class="format"><legend>Format</legend><ul class="column_list"><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="1" value="full_report" format="" id="full_report" checked="true" /><label for="full_report">Full Report</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="2" value="full_report" format="text" id="full_reporttext" /><label for="full_reporttext">Full Report (text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="3" value="expression" format="" id="expression" /><label for="expression">Expression</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="4" value="gene_table" format="" id="gene_table" /><label for="gene_table">Gene Table</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="5" value="gene_table" format="text" id="gene_tabletext" /><label for="gene_tabletext">Gene Table (text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="6" value="generif" format="" id="generif" /><label for="generif">GeneRIF</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="7" value="docsum" format="" id="docsum" /><label for="docsum">Summary</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="8" value="docsum" format="text" id="docsumtext" /><label for="docsumtext">Summary (text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="9" value="tabular" format="" id="tabular" /><label for="tabular">Tabular</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="10" value="tabular" format="text" id="tabulartext" /><label for="tabulartext">Tabular (text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="11" value="asn1" format="text" id="asn1text" /><label for="asn1text">ASN.1</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="12" value="xml" format="text" id="xmltext" /><label for="xmltext">XML</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="13" value="uilist" format="text" id="uilisttext" /><label for="uilisttext">UI List</label></li></ul></fieldset></div><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SetDisplay" sid="1" class="button_apply ncbipopper-close-button" style="display:none">Apply</button><h4 class="content_header send_to align_right jig-ncbipopper" id="sendto" data-jigconfig="triggerPosition:'bottom center', destPosition : 'top center',destSelector : '#send_to_menu', hasArrow : false, openEvent : 'click',closeEvent : 'click', isTriggerElementCloseClick: false, addCloseButton:true, groupName: 'entrez_pg', adjustFit:'none'"><a href="#" sourceContent="send_to_menu" class="tgt_dark">Send to:</a><script type="text/javascript">
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</script></h4><div id="send_to_menu" class="tabPopper send_to"><fieldset><legend>Choose Destination</legend><ul class="column_list"><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="1" value="File" id="dest_File" /><label for="dest_File">File</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="2" value="AddToClipboard" id="dest_AddToClipboard" /><label for="dest_AddToClipboard">Clipboard</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="3" value="AddToCollections" id="dest_AddToCollections" /><label for="dest_AddToCollections">Collections</label></li></ul></fieldset><div class="submenu file" id="submenu_File" style="display: none;"><p id="submenu_File_hint" class="hidden"></p><ul><li><label for="file_format">Format</label><select id="file_format" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FFormat" sid="1"><option value="full_report" format="text" selected="selected">Full Report (text)</option><option value="gene_table" format="text">Gene Table (text)</option><option value="docsum" format="text">Summary (text)</option><option value="tabular" format="text">Tabular (text)</option><option value="asn1" format="text">ASN.1</option><option value="xml" format="text">XML</option><option value="uilist" format="text">UI List</option></select></li></ul><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="1" class="button_apply file ncbipopper-close-button" type="submit" cmd="File">Create File</button></div><div class="submenu addtoclipboard" id="submenu_AddToClipboard" style="display: none;"><p id="submenu_AddToClipboard_hint" class="hidden"></p><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="2" class="button_apply clipboard ncbipopper-close-button" type="submit" cmd="AddToClipboard">Add to Clipboard</button></div><div class="submenu addtocollections" id="submenu_AddToCollections" style="display: none;"><p id="submenu_AddToCollections_hint" class="hidden"></p><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="3" class="button_apply collections ncbipopper-close-button" type="submit" cmd="AddToCollections">Add to Collections</button></div></div><div><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FileFormat" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastPresentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Presentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastPageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Sort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastSort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FileSort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Format" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastFormat" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevPageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevPresentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevSort" sid="1" type="hidden" value="" /><input type="hidden" id="coll_startindex" name="CollectionStartIndex" value="1" /></div></div>
|
||
<div>
|
||
|
||
|
||
|
||
</div>
|
||
<div class="">
|
||
<div><span id="result_sel" class="nowrap"></span><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_ResultsController.ResultCount" sid="1" type="hidden" id="resultcount" value="1" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_ResultsController.RunLastQuery" sid="1" type="hidden" /></div>
|
||
|
||
</div>
|
||
<div id="messagearea" class="empty">
|
||
|
||
|
||
|
||
|
||
</div>
|
||
<div class="rprt full-rprt">
|
||
<div>
|
||
<div class="rprt-header">
|
||
<input type="hidden" id="gene-tax-id" value="9606" />
|
||
<h1 class="title" id="gene-name"><span class="gn" style="padding-right:.5em;">CIITA</span> class II major histocompatibility complex transactivator [ <em class="tax">Homo sapiens</em> (human)
|
||
]
|
||
</h1>
|
||
<span class="geneid">Gene ID: 4261, updated on
|
||
4-Mar-2025</span>
|
||
</div>
|
||
<div class="download-datasets">
|
||
<script type="text/javascript" src="https://cdnjs.cloudflare.com/ajax/libs/axios/0.23.0/axios.min.js"></script>
|
||
<h4 class="download-datasets-popper jig-ncbipopper" id="download-asm" style="align-self:start" data-jigconfig="triggerPosition:'bottom center', destPosition : 'top center',destSelector : '#download-datasets-popper-menu', hasArrow : false, openEvent : 'click',closeEvent : 'click', isTriggerElementCloseClick: false, groupName: 'entrez_pg', adjustFit:'none'" role="button" aria-expanded="false" aria-haspopup="true">
|
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<svg alt="download" class="dlbtn-icon" x="0px" y="0px" width="15px" height="15px" viewBox="0 0 60 60" enable-background="new 0 0 60 60" xml:space="preserve">
|
||
<g>
|
||
<polygon points="48.75,36.25 48.75,48.75 11.25,48.75 11.25,36.25 5,36.25 5,55 55,55 55,36.25 "></polygon>
|
||
<polygon points="42.5,23.75 36.25,23.75 36.25,5 23.75,5 23.75,23.75 17.5,23.75 30,42.5 "></polygon>
|
||
</g>
|
||
</svg>
|
||
<a href="#">Download Datasets</a>
|
||
</h4>
|
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<div id="download-datasets-popper-menu" style="display:none;">
|
||
<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-gene-seq-fasta" value="FASTA_GENE" checked="checked" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-gene-seq-fasta">Gene Sequences (FASTA)</label>
|
||
</div>
|
||
<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-transcript-seq-fasta" value="FASTA_RNA" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-transcript-seq-fasta">Transcript sequences (FASTA)</label>
|
||
</div>
|
||
<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-protein-seq-fasta" value="FASTA_PROTEIN" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-protein-seq-fasta">Protein sequences(FASTA)</label>
|
||
</div>
|
||
<p style="margin-left:5px;">In addition, your package will include a detailed data report in both TSV and JSONL formats.</p>
|
||
<div class="input-group">
|
||
<label for="datasets-download-file-name">File name</label>
|
||
<input type="text" id="datasets-download-file-name" placeholder="Name your file" style="padding:5px;" value="CIITA_datasets.zip" />
|
||
</div>
|
||
<input type="hidden" id="download-datasets-base-url" value="https://api.ncbi.nlm.nih.gov/datasets/v2alpha/gene/download" />
|
||
<input type="hidden" id="gene-id-value" value="4261" />
|
||
<button id="datasets-download-submit" data-ga-action="click_begin_download" data-ga-label="download" class="jig-ncbibutton ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-gray" role="button">
|
||
<span class="ui-button-text">Download</span>
|
||
</button>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-body">
|
||
|
||
|
||
<div class="rprt-section gene-summary">
|
||
<section class="rprt-section-header" id="summary">
|
||
<h2 id="header-summary">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-summary .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Summary</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Summary_2" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div id="summaryDiv" class="section">
|
||
<dl id="summaryDl">
|
||
<dt class="noline"> Official
|
||
Symbol</dt>
|
||
<dd class="noline">CIITA<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
|
||
<dt> Official
|
||
Full Name</dt>
|
||
<dd>class II major histocompatibility complex transactivator<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
|
||
<dt>Primary source</dt>
|
||
<dd>
|
||
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7067" data-gblink-text="Ensembl">HGNC:HGNC:7067</a>
|
||
</dd>
|
||
<dt>See related</dt>
|
||
<dd>
|
||
<a href="http://www.ensembl.org/id/ENSG00000179583" data-gblink-text="Ensembl" class="genome-browser-link" data-genome-browser-link-sort="5" data-gb-url="http://www.ensembl.org/loc/ENSG00000179583">Ensembl:ENSG00000179583</a>
|
||
<a href="https://www.ncbi.nlm.nih.gov/omim/600005" data-gblink-text="Ensembl" ref="ordinalpos=1&ncbi_uid=4261&link_uid=600005">MIM:600005;</a>
|
||
<a href="https://www.alliancegenome.org/gene/HGNC:7067" data-gblink-text="Ensembl" ref="ordinalpos=1&ncbi_uid=4261&link_uid=HGNC:7067">AllianceGenome:HGNC:7067</a>
|
||
</dd>
|
||
<dt>Gene type</dt>
|
||
<dd>protein coding</dd>
|
||
<dt>RefSeq status</dt>
|
||
<dd>REVIEWED</dd>
|
||
<dt>Organism</dt>
|
||
<dd class="tax">
|
||
<a href="/Taxonomy/Browser/wwwtax.cgi?id=9606" ref="ordinalpos=1&ncbi_uid=4261&link_uid=9606">Homo sapiens</a>
|
||
</dd>
|
||
<dt>Lineage</dt>
|
||
<dd class="tax">Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo</dd>
|
||
<dt>Also known as</dt>
|
||
<dd>C2TA; NLRA; MHC2D1; MHC2TA; CIITAIV</dd>
|
||
<dt>Summary</dt>
|
||
<dd>This gene encodes a protein with an acidic transcriptional activation domain, 4 LRRs (leucine-rich repeats) and a GTP binding domain. The protein is located in the nucleus and acts as a positive regulator of class II major histocompatibility complex gene transcription, and is referred to as the "master control factor" for the expression of these genes. The protein also binds GTP and uses GTP binding to facilitate its own transport into the nucleus. Once in the nucleus it does not bind DNA but rather uses an intrinsic acetyltransferase (AT) activity to act in a coactivator-like fashion. Mutations in this gene have been associated with bare lymphocyte syndrome type II (also known as hereditary MHC class II deficiency or HLA class II-deficient combined immunodeficiency), increased susceptibility to rheumatoid arthritis, multiple sclerosis, and possibly myocardial infarction. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]</dd>
|
||
<dt>Expression</dt>
|
||
<dd>Broad expression in spleen (RPKM 12.7), lymph node (RPKM 11.9) and 19 other tissues <a href="#gene-expression">See more</a></dd>
|
||
<dt>Orthologs</dt>
|
||
<dd class="ortholog-links">
|
||
<a href="https://www.ncbi.nlm.nih.gov/gene/12265">mouse</a>
|
||
<a href="/gene/4261/ortholog/">all</a>
|
||
</dd>
|
||
<dt style="padding-top:.5em;">
|
||
<span class="new-icon">NEW</span>
|
||
</dt>
|
||
<dd style="padding-top:.5em;">
|
||
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/4261/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="gene_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Gene table</a></strong>
|
||
<br />
|
||
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/4261/products/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="transcript_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Transcript table</a></strong>
|
||
</dd>
|
||
</dl>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-genomic-context">
|
||
<section class="rprt-section-header" id="genomic-context">
|
||
<h2 id="header-genomic-context">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-context .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Genomic context</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Genomic_Context" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div class="gc_cont">
|
||
<div class="gt_cont_contents">
|
||
<div style="float:right"><span>See CIITA in </span><a href="/genome/gdv/?context=gene&acc=4261" class="link-to-gdv genome-browser-link" data-genome-browser-link-sort="1" data-acc="GCF_000001405.40">Genome Data Viewer</a> </div>
|
||
<dl class="dl-chr-info" style="float:left;margin-top:0;">
|
||
<dt>Location: </dt>
|
||
<dd>
|
||
<span style="display:inline-block;">16p13.13</span>
|
||
</dd>
|
||
</dl>
|
||
</div>
|
||
<dl class="dl-chr-info exon-count">
|
||
<dt>Exon count: </dt>
|
||
<dd>26</dd>
|
||
</dl>
|
||
<div class="ui-ncbigrid-outer-div" id="genomic-context-tbl-location">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="">
|
||
<thead>
|
||
<tr>
|
||
<th style="max-width:15%">Annotation release</th>
|
||
<th style="max-width:10%">Status</th>
|
||
<th>Assembly</th>
|
||
<th>
|
||
<span title="Chromosome">Chr</span>
|
||
</th>
|
||
<th>Location</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td>RS_2024_08</td>
|
||
<td>current</td>
|
||
<td>GRCh38.p14 (<a href="/assembly/GCF_000001405.40/" ref="ncbi_uid=4261&link_uid=GCF_000001405.40">GCF_000001405.40</a>)</td>
|
||
<td>16</td>
|
||
<td>NC_000016.10 (10866206..10943021) </td>
|
||
</tr>
|
||
<tr>
|
||
<td>RS_2024_08</td>
|
||
<td>current</td>
|
||
<td>T2T-CHM13v2.0 (<a href="/assembly/GCF_009914755.1/" ref="ncbi_uid=4261&link_uid=GCF_009914755.1">GCF_009914755.1</a>)</td>
|
||
<td>16</td>
|
||
<td>NC_060940.1 (10902173..10978992) </td>
|
||
</tr>
|
||
<tr>
|
||
<td>RS_2024_09</td>
|
||
<td>previous assembly</td>
|
||
<td>GRCh37.p13 (<a href="/assembly/GCF_000001405.25/" ref="ncbi_uid=4261&link_uid=GCF_000001405.25">GCF_000001405.25</a>)</td>
|
||
<td>16</td>
|
||
<td>NC_000016.9 (10971055..11030251) </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<p class="withnote margin_t2em"><strong>Chromosome 16 - NC_000016.10</strong><img usemap="#nbrMap4261_568815582" border="0" alt="Genomic Context describing neighboring genes" src="/gutils/geneneighb.fcgi?geneid=4261&nuc_gi=568815582&n0=NUBP1&n1=TVP23A&n2=LOC127883123&n3=LOC130058435&n4=LOC130058436&n5=LOC130058437&n6=LOC130058438&n7=LOC130058439&n8=LOC127883124&n9=LOC729945&n10=LOC130058440&n11=CIITA&n12=LOC126862287&n13=LOC130058441&n14=LOC130058442&n15=LOC130058443&n16=LOC130058444&n17=LOC130058445&n18=LOC130058446&n19=LOC130058447&n20=LOC130058448&n21=LOC130058449&n22=DEXI&n23=LOC130058450&n24=LOC130058451&n25=LOC130058452&n26=CLEC16A&n27=LOC130058453&n28=LOC130058454&n29=LOC130058455&n30=LOC130058456&n31=LOC125146406&n32=LOC129663760&n33=LOC127883125&n34=LOC127883126&n35=LOC130058457&n36=LOC129663761&n37=LOC127883127&n38=LOC125146407&n39=RPL7P46&n40=LOC127883128&n41=LOC127883129&n42=LOC130058458&n43=LOC130058459&n44=LOC130058460&n45=LOC130058461&n46=LOC130058462&n47=LOC130058463&n48=LOC121530617&n49=LOC105371081" /><map name="nbrMap4261_568815582" id="nbrMap4261_568815582">
|
||
<area shape="rect" onMouseOver="showtip(this,event,'NUBP iron-sulfur cluster assembly factor 1, cytosolic')" onMouseOut="hidetip()" coords="37,23,85,31" alt="Neighboring gene NUBP iron-sulfur cluster assembly factor 1, cytosolic" href="/gene/4682" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'NANOG hESC enhancer GRCh37_chr16:10883659-10884197')" onMouseOut="hidetip()" coords="40,35,110,43" alt="Neighboring gene NANOG hESC enhancer GRCh37_chr16:10883659-10884197" href="/gene/127883123" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'trans-golgi network vesicle protein 23 homolog A')" onMouseOut="hidetip()" coords="43,47,125,55" alt="Neighboring gene trans-golgi network vesicle protein 23 homolog A" href="/gene/780776" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10387')" onMouseOut="hidetip()" coords="44,59,114,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10387" href="/gene/130058435" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10388')" onMouseOut="hidetip()" coords="59,71,129,79" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10388" href="/gene/130058436" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10389')" onMouseOut="hidetip()" coords="65,83,135,91" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10389" href="/gene/130058437" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 7194')" onMouseOut="hidetip()" coords="72,95,142,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7194" href="/gene/130058438" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10390')" onMouseOut="hidetip()" coords="76,107,146,115" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10390" href="/gene/130058439" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr16:10932437-10932956')" onMouseOut="hidetip()" coords="80,119,150,127" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:10932437-10932956" href="/gene/127883124" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10391')" onMouseOut="hidetip()" coords="83,131,153,139" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10391" href="/gene/130058440" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'Rho GTPase activating protein 21 pseudogene')" onMouseOut="hidetip()" coords="95,23,150,31" alt="Neighboring gene Rho GTPase activating protein 21 pseudogene" href="/gene/729945" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'BRD4-independent group 4 enhancer GRCh37_chr16:10964767-10965966')" onMouseOut="hidetip()" coords="106,143,176,151" alt="Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr16:10964767-10965966" href="/gene/126862287" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10393')" onMouseOut="hidetip()" coords="111,35,181,43" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10393" href="/gene/130058442" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10395')" onMouseOut="hidetip()" coords="111,155,181,163" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10395" href="/gene/130058444" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10394')" onMouseOut="hidetip()" coords="111,167,181,175" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10394" href="/gene/130058443" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10392')" onMouseOut="hidetip()" coords="111,179,181,187" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10392" href="/gene/130058441" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10396')" onMouseOut="hidetip()" coords="113,191,183,199" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10396" href="/gene/130058445" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10397')" onMouseOut="hidetip()" coords="113,203,183,211" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10397" href="/gene/130058446" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10398')" onMouseOut="hidetip()" coords="113,215,183,223" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10398" href="/gene/130058447" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10399')" onMouseOut="hidetip()" coords="119,59,189,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10399" href="/gene/130058448" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10400')" onMouseOut="hidetip()" coords="140,71,210,79" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10400" href="/gene/130058449" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10401')" onMouseOut="hidetip()" coords="155,23,225,31" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10401" href="/gene/130058450" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 7195')" onMouseOut="hidetip()" coords="164,83,234,91" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7195" href="/gene/130058451" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10403')" onMouseOut="hidetip()" coords="166,95,236,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10403" href="/gene/130058453" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10402')" onMouseOut="hidetip()" coords="166,107,236,115" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10402" href="/gene/130058452" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10404')" onMouseOut="hidetip()" coords="170,119,240,127" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10404" href="/gene/130058454" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10405')" onMouseOut="hidetip()" coords="174,131,244,139" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10405" href="/gene/130058455" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10406')" onMouseOut="hidetip()" coords="184,35,254,43" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10406" href="/gene/130058456" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 12638')" onMouseOut="hidetip()" coords="188,143,258,151" alt="Neighboring gene Sharpr-MPRA regulatory region 12638" href="/gene/125146406" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ReSE screen-validated silencer GRCh37_chr16:11066007-11066184')" onMouseOut="hidetip()" coords="189,155,259,163" alt="Neighboring gene ReSE screen-validated silencer GRCh37_chr16:11066007-11066184" href="/gene/129663760" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'C-type lectin domain containing 16A')" onMouseOut="hidetip()" coords="191,59,423,67" alt="Neighboring gene C-type lectin domain containing 16A" href="/gene/23274" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'Dexi homolog')" onMouseOut="hidetip()" coords="194,167,227,175" alt="Neighboring gene Dexi homolog" href="/gene/28955" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr16:11073759-11074260')" onMouseOut="hidetip()" coords="195,179,265,187" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:11073759-11074260" href="/gene/127883125" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr16:11074261-11074760')" onMouseOut="hidetip()" coords="196,191,266,199" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:11074261-11074760" href="/gene/127883126" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 7196')" onMouseOut="hidetip()" coords="197,203,267,211" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7196" href="/gene/130058457" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ReSE screen-validated silencer GRCh37_chr16:11099817-11100053')" onMouseOut="hidetip()" coords="217,71,287,79" alt="Neighboring gene ReSE screen-validated silencer GRCh37_chr16:11099817-11100053" href="/gene/129663761" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'NANOG hESC enhancer GRCh37_chr16:11101530-11102234')" onMouseOut="hidetip()" coords="218,215,288,223" alt="Neighboring gene NANOG hESC enhancer GRCh37_chr16:11101530-11102234" href="/gene/127883127" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 10204')" onMouseOut="hidetip()" coords="225,227,295,235" alt="Neighboring gene Sharpr-MPRA regulatory region 10204" href="/gene/125146407" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:11144189-11144765')" onMouseOut="hidetip()" coords="253,23,323,31" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:11144189-11144765" href="/gene/127883128" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr16:11144766-11145343')" onMouseOut="hidetip()" coords="253,47,323,55" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:11144766-11145343" href="/gene/127883129" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10407')" onMouseOut="hidetip()" coords="255,35,325,43" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10407" href="/gene/130058458" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ribosomal protein L7 pseudogene 46')" onMouseOut="hidetip()" coords="259,83,304,91" alt="Neighboring gene ribosomal protein L7 pseudogene 46" href="/gene/642451" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10408')" onMouseOut="hidetip()" coords="287,95,357,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10408" href="/gene/130058459" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10409')" onMouseOut="hidetip()" coords="289,71,359,79" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10409" href="/gene/130058460" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10410')" onMouseOut="hidetip()" coords="294,107,364,115" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10410" href="/gene/130058461" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10411')" onMouseOut="hidetip()" coords="298,119,368,127" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10411" href="/gene/130058462" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 10412')" onMouseOut="hidetip()" coords="298,131,368,139" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10412" href="/gene/130058463" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 12604')" onMouseOut="hidetip()" coords="304,143,374,151" alt="Neighboring gene Sharpr-MPRA regulatory region 12604" href="/gene/121530617" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC105371081')" onMouseOut="hidetip()" coords="318,83,388,91" alt="Neighboring gene uncharacterized LOC105371081" href="/gene/105371081" />
|
||
</map>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-genomic-regions-transcripts-products">
|
||
<section class="rprt-section-header" id="genomic-regions-transcripts-products">
|
||
<h2 id="header-genomic-regions-transcripts-products">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-regions-transcripts-products .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Genomic regions, transcripts, and products</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Genomic_Regions_Transcripts_a" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<div style="text-align:right;">Go to <a href="#reference-sequences">reference sequence details</a></div>
|
||
</div>
|
||
<div>
|
||
<p class="choose">
|
||
<label for="accession" class="label">Genomic Sequence: </label>
|
||
<select name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.accessionList" sid="1" id="accessionList" data-taxid="9606" data-geneid="4261">
|
||
<option value="NC_000016.10_10866205_10943020">NC_000016.10 Chromosome 16 Reference GRCh38.p14 Primary Assembly</option>
|
||
<option value="NG_009628.1_5000_52785">NG_009628.1 RefSeqGene</option>
|
||
<option value="NC_060940.1_10902172_10978991">NC_060940.1 Chromosome 16 Alternate T2T-CHM13v2.0</option>
|
||
<option value="NC_000016.9_10971054_11030250">NC_000016.9 Chromosome 16 Reference GRCh37.p13 Primary Assembly</option>
|
||
</select>
|
||
</p>
|
||
</div>
|
||
<div id="NC_000016" class="divAccession">
|
||
<div class="seq-viewer">
|
||
<p class="note-link">
|
||
<strong>Go to nucleotide:</strong>
|
||
<a title="Nucleotide Graphic report" href="/nuccore/NC_000016.10?report=graph&from=10854683&to=10954542&app_context=Gene&assm_context=GCF_000001405.40" ref="ordinalpos=1&ncbi_uid=4261&link_uid=NC_000016.10">Graphics</a>
|
||
<a title="Nucleotide FASTA report" href="/nuccore/NC_000016.10?report=fasta&from=10866206&to=10943021" ref="ordinalpos=1&ncbi_uid=4261&link_uid=NC_000016.10">FASTA</a>
|
||
<a title="Nucleotide GenBank report" href="/nuccore/NC_000016.10?report=genbank&from=10866206&to=10943021" ref="ordinalpos=1&ncbi_uid=4261&link_uid=NC_000016.10">GenBank</a>
|
||
</p>
|
||
<div id="divNC_000016" class="SeqViewerApp" style="clear:both;" data-sv="appname=ncbigene&embedded=true&noslider=1&id=NC_000016.10&from=10854683&to=10954542&app_context=Gene&assm_context=GCF_000001405.40">
|
||
<a href="?appname=ncbigene&embedded=true&noslider=1&id=NC_000016.10&from=10854683&to=10954542&app_context=Gene&assm_context=GCF_000001405.40"></a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000016.10" sid="1" type="hidden" id="nucleotideLink_NC_000016_10_10866205_10943020" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_000016.10?report=graph&amp;from=10854683&amp;to=10954542&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" ref="ordinalpos=1&amp;ncbi_uid=4261&amp;link_uid=NC_000016.10">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_000016.10?report=fasta&amp;from=10866206&amp;to=10943021" ref="ordinalpos=1&amp;ncbi_uid=4261&amp;link_uid=NC_000016.10">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_000016.10?report=genbank&amp;from=10866206&amp;to=10943021" ref="ordinalpos=1&amp;ncbi_uid=4261&amp;link_uid=NC_000016.10">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000016.10" sid="1" type="hidden" id="relString_NC_000016_10_10866205_10943020" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000016.10&amp;from=10854683&amp;to=10954542&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NG_009628.1" sid="1" type="hidden" id="nucleotideLink_NG_009628_1_5000_52785" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NG_009628.1?report=graph&amp;from=1&amp;to=59953&amp;tracks=[key:sequence_track,name:Sequence,display_name:Sequence,category:Sequence,annots:Sequence,ShowLabel:false][key:gene_model_track,name:Genes---Unnamed,display_name:Genes,annots:Unnamed,Options:ShowAllButGenes,SNPs:false,CDSProductFeats:false,ShowLabelsForAllFeatures:true,HighlightMode:2][key:SNP_track,name:SNP,annots:SNP,Layout:Adaptive][key:SNP_Bins_track,name:Clinical Variants][key:SNP_Bins_track,name:Cited Variants][key:GWAS_track,name:GWAS Tracks,display_name:Association Results][key:alignment_track,category:Alignments,annots:Unnamed][key:alignment_track,category:Alignments,annots:NA000079160.1][key:alignment_track,category:Alignments,annots:NA000010065.1]" ref="ordinalpos=1&amp;ncbi_uid=4261&amp;link_uid=NG_009628.1">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NG_009628.1?report=fasta&amp;from=5001&amp;to=52786" ref="ordinalpos=1&amp;ncbi_uid=4261&amp;link_uid=NG_009628.1">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NG_009628.1?report=genbank&amp;from=5001&amp;to=52786" ref="ordinalpos=1&amp;ncbi_uid=4261&amp;link_uid=NG_009628.1">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NG_009628.1" sid="1" type="hidden" id="relString_NG_009628_1_5000_52785" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NG_009628.1&amp;from=1&amp;to=59953&amp;tracks=[key:sequence_track,name:Sequence,display_name:Sequence,category:Sequence,annots:Sequence,ShowLabel:false][key:gene_model_track,name:Genes---Unnamed,display_name:Genes,annots:Unnamed,Options:ShowAllButGenes,SNPs:false,CDSProductFeats:false,ShowLabelsForAllFeatures:true,HighlightMode:2][key:SNP_track,name:SNP,annots:SNP,Layout:Adaptive][key:SNP_Bins_track,name:Clinical Variants][key:SNP_Bins_track,name:Cited Variants][key:GWAS_track,name:GWAS Tracks,display_name:Association Results][key:alignment_track,category:Alignments,annots:Unnamed][key:alignment_track,category:Alignments,annots:NA000079160.1][key:alignment_track,category:Alignments,annots:NA000010065.1]" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_060940.1" sid="1" type="hidden" id="nucleotideLink_NC_060940_1_10902172_10978991" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_060940.1?report=graph&amp;from=10890649&amp;to=10990514&amp;app_context=Gene&amp;assm_context=GCF_009914755.1" ref="ordinalpos=1&amp;ncbi_uid=4261&amp;link_uid=NC_060940.1">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_060940.1?report=fasta&amp;from=10902173&amp;to=10978992" ref="ordinalpos=1&amp;ncbi_uid=4261&amp;link_uid=NC_060940.1">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_060940.1?report=genbank&amp;from=10902173&amp;to=10978992" ref="ordinalpos=1&amp;ncbi_uid=4261&amp;link_uid=NC_060940.1">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_060940.1" sid="1" type="hidden" id="relString_NC_060940_1_10902172_10978991" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_060940.1&amp;from=10890649&amp;to=10990514&amp;app_context=Gene&amp;assm_context=GCF_009914755.1" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000016.9" sid="1" type="hidden" id="nucleotideLink_NC_000016_9_10971054_11030250" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_000016.9?report=graph&amp;from=10962175&amp;to=11039129&amp;app_context=Gene&amp;assm_context=GCF_000001405.25" ref="ordinalpos=1&amp;ncbi_uid=4261&amp;link_uid=NC_000016.9">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_000016.9?report=fasta&amp;from=10971055&amp;to=11030251" ref="ordinalpos=1&amp;ncbi_uid=4261&amp;link_uid=NC_000016.9">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_000016.9?report=genbank&amp;from=10971055&amp;to=11030251" ref="ordinalpos=1&amp;ncbi_uid=4261&amp;link_uid=NC_000016.9">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000016.9" sid="1" type="hidden" id="relString_NC_000016_9_10971054_11030250" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000016.9&amp;from=10962175&amp;to=11039129&amp;app_context=Gene&amp;assm_context=GCF_000001405.25" />
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-gene-expression">
|
||
<section class="rprt-section-header" id="gene-expression">
|
||
<h2 id="header-gene-expression">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-gene-expression .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Expression</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Expression" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<div style="text-align:right;">
|
||
<a href="/gene/4261/?report=expression" data-url="/gene/4261/?report=expression" id="gene-expression-see-details">See details</a>
|
||
</div>
|
||
<div id="gene-expression-app" data-url="https://www.ncbi.nlm.nih.gov/gene/4261" data-report-type="summary">
|
||
<div>
|
||
<script type="text/javascript">
|
||
|
||
window.tissues_data = {'adrenal 10wk': {'id': '4261_Adrenal_10wk_PRJNA270632', 'gene': 4261, 'source_name': 'adrenal 10wk', 'full_rpkm': 0.161424, 'exp_rpkm': 0.161, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734397665738794}, 'adrenal 16wk': {'id': '4261_Adrenal_16wk_PRJNA270632', 'gene': 4261, 'source_name': 'adrenal 16wk', 'full_rpkm': 0.133625, 'exp_rpkm': 0.134, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734397666787328}, 'adrenal 18wk': {'id': '4261_Adrenal_18wk_PRJNA270632', 'gene': 4261, 'source_name': 'adrenal 18wk', 'full_rpkm': 0.210453, 'exp_rpkm': 0.21, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734397666787329}, 'adrenal 20wk': {'id': '4261_Adrenal_20wk_PRJNA270632', 'gene': 4261, 'source_name': 'adrenal 20wk', 'full_rpkm': 0.209132, 'exp_rpkm': 0.209, 'var': 0.00245872, 'project_desc': 'PRJNA270632', '_version_': 1785734397666787330}, 'heart 10wk': {'id': '4261_Heart_10wk;_PRJNA270632', 'gene': 4261, 'source_name': 'heart 10wk', 'full_rpkm': 0.122525, 'exp_rpkm': 0.123, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734397666787331}, 'heart 11wk': {'id': '4261_Heart_11wk;_PRJNA270632', 'gene': 4261, 'source_name': 'heart 11wk', 'full_rpkm': 0.0728212, 'exp_rpkm': 0.0728, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734397666787332}, 'heart 17wk': {'id': '4261_Heart_17wk;_PRJNA270632', 'gene': 4261, 'source_name': 'heart 17wk', 'full_rpkm': 0.0553073, 'exp_rpkm': 0.0553, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734397666787333}, 'heart 18wk': {'id': '4261_Heart_18wk;_PRJNA270632', 'gene': 4261, 'source_name': 'heart 18wk', 'full_rpkm': 0.0978343, 'exp_rpkm': 0.0978, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734397666787334}, 'heart 20wk': {'id': '4261_Heart_20wk_PRJNA270632', 'gene': 4261, 'source_name': 'heart 20wk', 'full_rpkm': 0.0433463, 'exp_rpkm': 0.0433, 'var': 0.001315485, 'project_desc': 'PRJNA270632', '_version_': 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'gene': 4261, 'source_name': 'intestine 20wk', 'full_rpkm': 0.246648, 'exp_rpkm': 0.247, 'var': 0.0139946, 'project_desc': 'PRJNA270632', '_version_': 1785734397666787340}, 'kidney 10wk': {'id': '4261_Kidney_10wk_PRJNA270632', 'gene': 4261, 'source_name': 'kidney 10wk', 'full_rpkm': 0.0824438, 'exp_rpkm': 0.0824, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734397666787341}, 'kidney 16wk': {'id': '4261_Kidney_16wk_PRJNA270632', 'gene': 4261, 'source_name': 'kidney 16wk', 'full_rpkm': 0.0617871, 'exp_rpkm': 0.0618, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734397666787342}, 'kidney 20wk': {'id': '4261_Kidney_20wk_PRJNA270632', 'gene': 4261, 'source_name': 'kidney 20wk', 'full_rpkm': 0.034011, 'exp_rpkm': 0.034, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734397666787343}, 'lung 10wk': {'id': '4261_Lung_10wk_PRJNA270632', 'gene': 4261, 'source_name': 'lung 10wk', 'full_rpkm': 0.12105, 'exp_rpkm': 0.121, 'var': 6.54124e-05, 'project_desc': 'PRJNA270632', '_version_': 1785734397666787344}, 'lung 17wk': {'id': '4261_Lung_17wk_PRJNA270632', 'gene': 4261, 'source_name': 'lung 17wk', 'full_rpkm': 0.1132, 'exp_rpkm': 0.113, 'var': 0.0001244034, 'project_desc': 'PRJNA270632', '_version_': 1785734397666787345}, 'lung 20wk': {'id': '4261_Lung_20wk_PRJNA270632', 'gene': 4261, 'source_name': 'lung 20wk', 'full_rpkm': 0.121172, 'exp_rpkm': 0.121, 'var': 3.4696e-05, 'project_desc': 'PRJNA270632', '_version_': 1785734397666787346}, 'stomach 10wk': {'id': '4261_Stomach_10wk_PRJNA270632', 'gene': 4261, 'source_name': 'stomach 10wk', 'full_rpkm': 0.147635, 'exp_rpkm': 0.148, 'var': 0.000865286, 'project_desc': 'PRJNA270632', '_version_': 1785734397666787347}, 'stomach 16wk': {'id': '4261_Stomach_16wk_PRJNA270632', 'gene': 4261, 'source_name': 'stomach 16wk', 'full_rpkm': 0.122618, 'exp_rpkm': 0.123, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734397666787348}, 'stomach 18wk': {'id': '4261_Stomach_18wk_PRJNA270632', 'gene': 4261, 'source_name': 'stomach 18wk', 'full_rpkm': 0.165634, 'exp_rpkm': 0.166, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734397666787349}, 'stomach 20wk': {'id': '4261_Stomach_20wk_PRJNA270632', 'gene': 4261, 'source_name': 'stomach 20wk', 'full_rpkm': 0.230211, 'exp_rpkm': 0.23, 'var': 0.00840162, 'project_desc': 'PRJNA270632', '_version_': 1785734397666787350}};
|
||
|
||
|
||
|
||
|
||
window.details_data = {"adrenal 10wk": [{"id": "metadata_9606_SAMN03267754", "gene": 4261, "sample_id": "SAMN03267754", "full_rpkm": 0.161424, "exp_rpkm": 0.161, "exp_total": 9547, "project_desc": "PRJNA270632", "_version_": 1785734387345653765, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 10wk", "exp_Mcount": 4852.92}], "adrenal 16wk": [{"id": "metadata_9606_SAMN03267755", "gene": 4261, "sample_id": "SAMN03267755", "full_rpkm": 0.133625, "exp_rpkm": 0.134, "exp_total": 11838, "project_desc": "PRJNA270632", "_version_": 1785734387345653764, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 16wk", "exp_Mcount": 7269.31}], "adrenal 18wk": [{"id": "metadata_9606_SAMN03267761", "gene": 4261, "sample_id": "SAMN03267761", "full_rpkm": 0.210453, "exp_rpkm": 0.21, "exp_total": 17121, "project_desc": "PRJNA270632", "_version_": 1785734387345653763, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 18wk", 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[{"id": "metadata_9606_SAMN03267752", "gene": 4261, "sample_id": "SAMN03267752", "full_rpkm": 0.115399, "exp_rpkm": 0.115, "exp_total": 10982, "project_desc": "PRJNA270632", "_version_": 1785734387344605203, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 10wk", "exp_Mcount": 7808.8}, {"id": "metadata_9606_SAMN03267759", "gene": 4261, "sample_id": "SAMN03267759", "full_rpkm": 0.100079, "exp_rpkm": 0.1, "exp_total": 8424, "project_desc": "PRJNA270632", "_version_": 1785734387344605204, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 10wk", "exp_Mcount": 6906.84}], "intestine 11wk": [{"id": "metadata_9606_SAMN03267758", "gene": 4261, "sample_id": "SAMN03267758", "full_rpkm": 0.122545, "exp_rpkm": 0.123, "exp_total": 6474, "project_desc": "PRJNA270632", "_version_": 1785734387344605202, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 11wk", "exp_Mcount": 4334.9}], "intestine 15wk": [{"id": 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"metadata_9606_SAMN03267778", "gene": 4261, "sample_id": "SAMN03267778", "full_rpkm": 0.102046, "exp_rpkm": 0.102, "exp_total": 7778, "project_desc": "PRJNA270632", "_version_": 1785734387344605191, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 17wk", "exp_Mcount": 6254.23}, {"id": "metadata_9606_SAMN03267776", "gene": 4261, "sample_id": "SAMN03267776", "full_rpkm": 0.124353, "exp_rpkm": 0.124, "exp_total": 5673, "project_desc": "PRJNA270632", "_version_": 1785734387344605192, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 17wk", "exp_Mcount": 3743.33}], "lung 20wk": [{"id": "metadata_9606_SAMN03267780", "gene": 4261, "sample_id": "SAMN03267780", "full_rpkm": 0.115282, "exp_rpkm": 0.115, "exp_total": 13024, "project_desc": "PRJNA270632", "_version_": 1785734387344605189, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 20wk", "exp_Mcount": 9270.13}, {"id": "metadata_9606_SAMN03267768", "gene": 4261, "sample_id": "SAMN03267768", "full_rpkm": 0.127063, "exp_rpkm": 0.127, "exp_total": 9837, "project_desc": "PRJNA270632", "_version_": 1785734387344605190, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 20wk", "exp_Mcount": 6352.54}], "stomach 10wk": [{"id": "metadata_9606_SAMN03267773", "gene": 4261, "sample_id": "SAMN03267773", "full_rpkm": 0.11822, "exp_rpkm": 0.118, "exp_total": 9483, "project_desc": "PRJNA270632", "_version_": 1785734387344605187, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 10wk", "exp_Mcount": 6582.02}, {"id": "metadata_9606_SAMN03267779", "gene": 4261, "sample_id": "SAMN03267779", "full_rpkm": 0.177051, "exp_rpkm": 0.177, "exp_total": 15609, "project_desc": "PRJNA270632", "_version_": 1785734387344605188, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 10wk", "exp_Mcount": 7234.02}], "stomach 16wk": [{"id": "metadata_9606_SAMN03267774", "gene": 4261, "sample_id": "SAMN03267774", "full_rpkm": 0.122618, "exp_rpkm": 0.123, "exp_total": 9294, "project_desc": "PRJNA270632", "_version_": 1785734387344605186, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 16wk", "exp_Mcount": 6219.43}], "stomach 18wk": [{"id": "metadata_9606_SAMN03267771", "gene": 4261, "sample_id": "SAMN03267771", "full_rpkm": 0.165634, "exp_rpkm": 0.166, "exp_total": 11749, "project_desc": "PRJNA270632", "_version_": 1785734387344605185, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 18wk", "exp_Mcount": 5820.42}], "stomach 20wk": [{"id": "metadata_9606_SAMN03267765", "gene": 4261, "sample_id": "SAMN03267765", "full_rpkm": 0.347565, "exp_rpkm": 0.348, "exp_total": 19038, "project_desc": "PRJNA270632", "_version_": 1785734387342508032, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4494.58}, {"id": "metadata_9606_SAMN03267781", "gene": 4261, "sample_id": "SAMN03267781", "full_rpkm": 0.219214, "exp_rpkm": 0.219, "exp_total": 12199, "project_desc": "PRJNA270632", "_version_": 1785734387343556608, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4566.24}, {"id": "metadata_9606_SAMN03267783", "gene": 4261, "sample_id": "SAMN03267783", "full_rpkm": 0.123853, "exp_rpkm": 0.124, "exp_total": 7252, "project_desc": "PRJNA270632", "_version_": 1785734387344605184, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4804.58}]}
|
||
window.taxId = 9606
|
||
</script>
|
||
|
||
|
||
<div>
|
||
|
||
|
||
|
||
<select name="p" id="project-selector">
|
||
|
||
|
||
<option value="SRP051249" selected="selected" data-bioproject="PRJNA270632">
|
||
|
||
Tissue-specific circular RNA induction during human fetal development
|
||
|
||
</option>
|
||
|
||
|
||
|
||
<option value="SRP056969" data-bioproject="PRJNA280600">
|
||
|
||
RNA sequencing of total RNA from 20 human tissues
|
||
|
||
|
||
</option>
|
||
|
||
|
||
|
||
<option value="ERP003613" data-bioproject="PRJEB4337">
|
||
|
||
HPA RNA-seq normal tissues
|
||
|
||
|
||
</option>
|
||
|
||
|
||
|
||
</select>
|
||
|
||
|
||
|
||
<ul id="project-summary">
|
||
<li id="project-summary-title">Project title:
|
||
|
||
Tissue-specific circular RNA induction during human fetal development
|
||
|
||
</li>
|
||
|
||
|
||
<li id="project-summary-desc">Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA</li>
|
||
|
||
|
||
|
||
<li id="project-summary-bioprojects">BioProject: <a href="/bioproject/PRJNA270632/">PRJNA270632</a>
|
||
</li>
|
||
|
||
<li id="project-summary-pubs">Publication:
|
||
|
||
|
||
<span><a href="/pubmed/26076956/">PMID 26076956</a></span>
|
||
|
||
</li>
|
||
|
||
|
||
<li id="project-summary-analysis-date">Analysis date: Mon Apr 2 22:54:59 2018</li>
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
<div id="gene-expr-details" class="expression-chart"></div>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<script type="text/javascript" src="https://www.gstatic.com/charts/loader.js"></script>
|
||
<script type="text/javascript">
|
||
google.charts.load('current', {
|
||
'packages':[ 'corechart']
|
||
});
|
||
|
||
</script>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-bibliography">
|
||
<section class="rprt-section-header" id="bibliography"><h2 id="header-bibliography"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-bibliography .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Bibliography</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Bibliography" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
|
||
<div class="rprt-section-body" style="">
|
||
<div class="generif-pubmed">
|
||
<h3 id="relatedarticlesinpubmed">
|
||
<a href="#" class="jig-ncbitoggler-open">Related articles in PubMed</a>
|
||
</h3>
|
||
<div class="generefbl-link">
|
||
<ol class="generef-link">
|
||
<li>
|
||
<a href="/pubmed/19659749/" ref="ordinalpos=1&ncbi_uid=4261&link_uid=19659749">MHC2TA rs4774C and HHV-6A active replication in multiple sclerosis patients.</a>
|
||
<span class="pubmed-auth-date"> Alvarez-Lafuente R, <em>et al</em>. Eur J Neurol, 2010 Jan. PMID 19659749</span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/16776848/" ref="ordinalpos=2&ncbi_uid=4261&link_uid=16776848">The MHC2TA -168A>G gene polymorphism is not associated with rheumatoid arthritis in Austrian patients.</a>
|
||
<span class="pubmed-auth-date"> Yazdani-Biuki B, <em>et al</em>. Arthritis Res Ther, 2006. PMID 16776848, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC1779415/" ref="ordinalpos=0&ncbi_uid=4261&link_uid=PMC1779415">Free PMC Article</a></span></span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/16920747/" ref="ordinalpos=3&ncbi_uid=4261&link_uid=16920747">MHC2TA promoter polymorphism (-168*G/A, rs3087456) is not associated with susceptibility to rheumatoid arthritis in British Caucasian rheumatoid arthritis patients.</a>
|
||
<span class="pubmed-auth-date"> Harrison P, <em>et al</em>. Rheumatology (Oxford), 2007 Mar. PMID 16920747</span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/16996793/" ref="ordinalpos=4&ncbi_uid=4261&link_uid=16996793">Not polymorphism but methylation of class II transactivator gene promoter IV associated with persistent HBV infection.</a>
|
||
<span class="pubmed-auth-date"> He Y, <em>et al</em>. J Clin Virol, 2006 Dec. PMID 16996793</span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/17012290/" ref="ordinalpos=5&ncbi_uid=4261&link_uid=17012290">Role of the MHC2TA gene in autoimmune diseases.</a>
|
||
<span class="pubmed-auth-date"> Martínez A, <em>et al</em>. Ann Rheum Dis, 2007 Mar. PMID 17012290, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC1855999/" ref="ordinalpos=0&ncbi_uid=4261&link_uid=PMC1855999">Free PMC Article</a></span></span>
|
||
</li>
|
||
</ol>
|
||
<p class="see-all-pm">
|
||
<a href="/pubmed?LinkName=gene_pubmed&from_uid=4261" title="See all 223 citations in Pubmed">See all (223) citations in PubMed</a>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="generif-pubmed generif">
|
||
<h3 id="generifsgenereferencesintofunctions">
|
||
<a href="#" class="jig-ncbitoggler-open">GeneRIFs: Gene References Into Functions</a>
|
||
</h3>
|
||
<div>
|
||
<a href="/gene/about-generif" class="whatisthis">What's a GeneRIF?</a>
|
||
<div class="generefbl-link">
|
||
<ol class="generef-link">
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/38073129" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=4261&link_uid=38073129">The intrinsically disordered transcriptional activation domain of CIITA is functionally tuneable by single substitutions: An exception or a new paradigm?</a>
|
||
<div id="gene-popper1" class="gene-rif-popper">Title: The intrinsically disordered transcriptional activation domain of CIITA is functionally tuneable by single substitutions: An exception or a new paradigm?</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/37467968" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=4261&link_uid=37467968">The NLR member CIITA: Master controller of adaptive and intrinsic immunity and unexpected tool in cancer immunotherapy.</a>
|
||
<div id="gene-popper2" class="gene-rif-popper">Title: The NLR member CIITA: Master controller of adaptive and intrinsic immunity and unexpected tool in cancer immunotherapy.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/37108368" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=4261&link_uid=37108368">NLRC5-CIITA Fusion Protein as an Effective Inducer of MHC-I Expression and Antitumor Immunity.</a>
|
||
<div id="gene-popper3" class="gene-rif-popper">Title: NLRC5-CIITA Fusion Protein as an Effective Inducer of MHC-I Expression and Antitumor Immunity.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/36223747" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=4261&link_uid=36223747">Cancer-specific T helper shared and neo-epitopes uncovered by expression of the MHC class II master regulator CIITA.</a>
|
||
<div id="gene-popper4" class="gene-rif-popper">Title: Cancer-specific T helper shared and neo-epitopes uncovered by expression of the MHC class II master regulator CIITA.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/35835655" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=4261&link_uid=35835655">Novel missense variant of CIITA contributing to endometriosis.</a>
|
||
<div id="gene-popper5" class="gene-rif-popper">Title: Novel missense variant of CIITA contributing to endometriosis.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/34180145" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=4261&link_uid=34180145">CIITA gene polymorphism (rs3087456) in systemic lupus erythematosus and rheumatoid arthritis: A population-based cohort study.</a>
|
||
<div id="gene-popper6" class="gene-rif-popper">Title: CIITA gene polymorphism (rs3087456) in systemic lupus erythematosus and rheumatoid arthritis: A population-based cohort study.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/32853948" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=4261&link_uid=32853948">Inactivating mutations of class II transactivator (CIITA) gene in gastric and colorectal cancers.</a>
|
||
<div id="gene-popper7" class="gene-rif-popper">Title: Inactivating mutations of class II transactivator (CIITA) gene in gastric and colorectal cancers.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/33754173" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=4261&link_uid=33754173">HLA-DRB1 genes and the expression dynamics of HLA CIITA determine the susceptibility to T2DM.</a>
|
||
<div id="gene-popper8" class="gene-rif-popper">Title: HLA-DRB1 genes and the expression dynamics of HLA CIITA determine the susceptibility to T2DM.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/32103629" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=4261&link_uid=32103629">Genetic variants in class II transactivator are associated with chronic hepatitis B virus infection in the Han Chinese population.</a>
|
||
<div id="gene-popper9" class="gene-rif-popper">Title: Genetic variants in class II transactivator are associated with chronic hepatitis B virus infection in the Han Chinese population.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/33499042" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=4261&link_uid=33499042">The MHC Class II Transactivator CIITA: Not (Quite) the Odd-One-Out Anymore among NLR Proteins.</a>
|
||
<div id="gene-popper10" class="gene-rif-popper">Title: The MHC Class II Transactivator CIITA: Not (Quite) the Odd-One-Out Anymore among NLR Proteins.</div>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
<div class="submit-genrif">
|
||
<span>Submit:</span>
|
||
<a href="/gene/submit-generif/?geneId=4261&sym=CIITA&name=class II major histocompatibility complex transactivator&org=Homo sapiens">New GeneRIF</a>
|
||
<a href="/RefSeq/update.cgi?geneid=4261&symbol=CIITA;task=fixpub">Correction</a>
|
||
<a href="https://www.ncbi.nlm.nih.gov/gene?db=gene&report=generif&term=4261" class="seeall-generif">See all GeneRIFs (168)</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-phenotypes">
|
||
<section class="rprt-section-header" id="phenotypes">
|
||
<h2 id="header-phenotypes">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-phenotypes .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Phenotypes</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Phenotype" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body info-phenotype">
|
||
<p class="nochild-link">
|
||
<a href="/gtr/tests/?term=CIITA[gene]">Find tests for this gene in the NIH Genetic Testing Registry (GTR)</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/gap/PheGenI?tab=1&gene=4261">Review eQTL and phenotype association data in this region using PheGenI</a>
|
||
</p>
|
||
<div>
|
||
<h3 id="associatedconditions">Associated conditions</h3>
|
||
<table class="jig-ncbigrid gtr-associated-cond">
|
||
<thead>
|
||
<tr>
|
||
<th class="description">Description</th>
|
||
<th>Tests</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td>
|
||
<a href="/gtr/conditions/CN377826" ref="ncbi_uid=4261&link_uid=CN377826">MHC class II deficiency 1</a>
|
||
<div class="gtr-associated-cond-extra">
|
||
<span class="gtr-associated-cond-extra-i">MedGen: <a href="/medgen/CN377826" ref="ncbi_uid=4261&link_uid=CN377826">CN377826</a></span>
|
||
<span class="gtr-associated-cond-extra-i">OMIM: <a href="https://www.ncbi.nlm.nih.gov/omim/209920" ref="ncbi_uid=4261"> 209920</a></span>
|
||
<span class="gtr-associated-cond-extra-i">GeneReviews: <span>Not available</span></span>
|
||
</div>
|
||
</td>
|
||
<td>
|
||
<span class="gtr-na">not available</span>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td>
|
||
<a href="/gtr/conditions/C0003873" ref="ncbi_uid=4261&link_uid=C0003873">Rheumatoid arthritis</a>
|
||
<div class="gtr-associated-cond-extra">
|
||
<span class="gtr-associated-cond-extra-i">MedGen: <a href="/medgen/C0003873" ref="ncbi_uid=4261&link_uid=C0003873">C0003873</a></span>
|
||
<span class="gtr-associated-cond-extra-i">OMIM: <a href="https://www.ncbi.nlm.nih.gov/omim/180300" ref="ncbi_uid=4261"> 180300</a></span>
|
||
<span class="gtr-associated-cond-extra-i">GeneReviews: <span>Not available</span></span>
|
||
</div>
|
||
</td>
|
||
<td>
|
||
<a href="/gtr/tests/?term=C0003873[DISCUI]&condition=C0003873&compare_labs=1" ref="ncbi_uid=4261">Compare labs</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
<div>
|
||
<h3 id="ebigwascatalog">EBI GWAS Catalog</h3>
|
||
<table class="jig-ncbigrid gtr-associated-cond" data-jigconfig="isPageable: true, pageSize: 10">
|
||
<thead>
|
||
<tr>
|
||
<th class="description">Description</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td>Genome-wide association identifies multiple ulcerative colitis susceptibility loci.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/20228799">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/20228799">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Multiple common variants for celiac disease influencing immune gene expression.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/20190752">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/20190752">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-variation">
|
||
<section class="rprt-section-header" id="variation">
|
||
<h2 id="header-variation">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-variation .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Variation</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.variation" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<p class="nochild-link">
|
||
<a href="/clinvar/?term=CIITA[gene]" ref="log$=recordlinks">See variants in ClinVar</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/dbvar?LinkName=gene_dbvar&from_uid=4261" ref="log$=recordlinks">See studies and variants in dbVar</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/variation/view/?q=4261[geneid]&assm=GCF_000001405.25" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh37.p13)">See Variation Viewer (GRCh37.p13)</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/variation/view/?q=4261[geneid]" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh38)">See Variation Viewer (GRCh38)</a>
|
||
</p>
|
||
<set></set>
|
||
<set></set>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-HIV-1-interactions">
|
||
<section class="rprt-section-header" id="HIV-1-interactions">
|
||
<h2 id="header-HIV-1-interactions">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-HIV-1-interactions .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">HIV-1 interactions</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.HIV1_interactions" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div class="fgrid">
|
||
<h3 id="proteininteractions">Protein interactions</h3>
|
||
<table summary="protein interactions" class="jig-ncbigrid">
|
||
<thead>
|
||
<tr>
|
||
<th id="hivprotein">Protein</th>
|
||
<th id="gene-hivprotein">Gene</th>
|
||
<th id="hivinter">Interaction</th>
|
||
<th id="hivpub">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="hivprotein">
|
||
<a href="/protein/28876544">Envelope surface glycoprotein gp120</a>
|
||
</td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155971">env</a>
|
||
</td>
|
||
<td headers="hivinter">CIITA-mediated enhancement of HIV-1 infection is gp120/gp41/CD4-dependent and occurs at the early steps in the infection cycle</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 21041720" href="/pubmed/21041720">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein">
|
||
<a href="/protein/19172954">Envelope transmembrane glycoprotein gp41</a>
|
||
</td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155971">env</a>
|
||
</td>
|
||
<td headers="hivinter">CIITA-mediated enhancement of HIV-1 infection is gp120/gp41/CD4-dependent and occurs at the early steps in the infection cycle</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 21041720" href="/pubmed/21041720">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein">
|
||
<a href="/protein/28872819">Gag-Pol</a>
|
||
</td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155348">gag-pol</a>
|
||
</td>
|
||
<td headers="hivinter">CIITA increases the viral protease activity through increased HIV-1 Gag-Pol levels</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 20585587" href="/pubmed/20585587">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein">
|
||
<a href="/protein/9629360">Pr55(Gag)</a>
|
||
</td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155030">gag</a>
|
||
</td>
|
||
<td headers="hivinter">CIITA enhancement of HIV-1 Gag processing is through the viral protease activity</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 20585587" href="/pubmed/20585587">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein"></td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155030">gag</a>
|
||
</td>
|
||
<td headers="hivinter">Gag production is significantly increased by fusing HIV-1-infected CD4- and CXCR4-expressing rat fibroblasts with uninfected human T-, B-, and macrophage cell lines. This process is regulated by HP68 and MHC class II transactivator (CIITA)</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 20585587,17222823" href="/pubmed/20585587,17222823">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein">
|
||
<a href="/protein/9629358">Tat</a>
|
||
</td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155871">tat</a>
|
||
</td>
|
||
<td headers="hivinter">HIV-1 Tat transactivation is inhibited by the amino acids 64-285 in CIITA in U937 cells</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 27089879" href="/pubmed/27089879">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein"></td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155871">tat</a>
|
||
</td>
|
||
<td headers="hivinter">The HLA class II transcriptional activator, CIITA, inhibits HIV-1 Tat and virus replication</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 27089879,12355430,11118314" href="/pubmed/27089879,12355430,11118314">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein"></td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155871">tat</a>
|
||
</td>
|
||
<td headers="hivinter">HIV-1 Tat inhibits CIITA by competing with CIITA for binding to P-TEFb</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 10661406" href="/pubmed/10661406">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein"></td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155871">tat</a>
|
||
</td>
|
||
<td headers="hivinter">HIV-1 Tat downregulates expression of MHC class II genes in antigen-presenting cells (APC) by inhibiting the transactivator of MHC class II genes, CIITA</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 11118314,10661406" href="/pubmed/11118314,10661406">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein">
|
||
<a href="/protein/19172948">capsid</a>
|
||
</td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155030">gag</a>
|
||
</td>
|
||
<td headers="hivinter">p24 production is significantly increased by fusing HIV-1-infected CD4- and CXCR4-expressing rat fibroblasts with uninfected human T-, B-, and macrophage cell lines. This process is regulated by HP68 and MHC class II transactivator (CIITA)</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 17222823" href="/pubmed/17222823">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein">
|
||
<a href="/protein/25121906">retropepsin</a>
|
||
</td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155348">gag-pol</a>
|
||
</td>
|
||
<td headers="hivinter">CIITA enhancement of HIV-1 Gag processing is through the viral protease activity, which results from increased levels of HIV-1 Gag-Pol by CIITA</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 20585587" href="/pubmed/20585587">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
<p class="withnote">
|
||
<a class="note" href="/genome/viruses/retroviruses/hiv-1/interactions/">Go to the HIV-1, Human Interaction Database </a>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-pathways">
|
||
<section class="rprt-section-header" id="pathways">
|
||
<h2 id="header-pathways">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-pathways .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Pathways from PubChem</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<ul class="geneinfo-subsec infopathway">
|
||
<iframe title="Pathways in which the gene target is involved" class="pubchem-widget" scrolling="no" src="https://pubchem.ncbi.nlm.nih.gov/gene/4261#section=Pathways&embed=true&hide_all_headings=true&page_size=25" style="border: 0; width: 100%;"></iframe>
|
||
<script type="text/javascript" src="https://pubchem.ncbi.nlm.nih.gov/pcfe/libs/iframeResizer.min.js"></script>
|
||
<script type="text/javascript">iFrameResize({log: false, checkOrigin: false}, '.pubchem-widget')</script>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-interactions">
|
||
<section class="rprt-section-header" id="interactions">
|
||
<h2 id="header-interactions">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-interactions .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Interactions</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Interactions" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<table summary="Gene Interaction" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/4261/data/interaction/',webserviceParams: 'p$l=Ajax&p$debugoutput=off', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th id="inter-prod">Products</th>
|
||
<th id="inter-interactant">Interactant</th>
|
||
<th id="inter-otherGene">Other Gene</th>
|
||
<th id="inter-compl">Complex</th>
|
||
<th id="inter-source">Source</th>
|
||
<th id="inter-pubs">Pubs</th>
|
||
<th id="inter-desc">Description</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody></tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-general-gene-info">
|
||
<section class="rprt-section-header" id="general-gene-info">
|
||
<h2 id="header-general-gene-info">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-gene-info .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">General gene information</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.General_Gene_Information" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
|
||
<div class="rprt-section-body" style="">
|
||
<div id="gene-markers">
|
||
<h3 id="markers">
|
||
<a class="jig-ncbitoggler">Markers</a>
|
||
</h3>
|
||
<div>
|
||
<ul class="marker odd">
|
||
<li class="marker">RH65129 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=92434%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=4261&link_uid=92434">UniSTS:92434</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">GDB:434012 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=157204%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=4261&link_uid=157204">UniSTS:157204</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">PMC83901P1 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=273434%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=4261&link_uid=273434">UniSTS:273434</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">RH79123 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=15185%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=4261&link_uid=15185">UniSTS:15185</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">PMC133907P1 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=270680%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=4261&link_uid=270680">UniSTS:270680</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">PMC133907P2 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=270681%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=4261&link_uid=270681">UniSTS:270681</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">PMC133907P3 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=270682%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=4261&link_uid=270682">UniSTS:270682</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">PMC133907P4 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=270683%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=4261&link_uid=270683">UniSTS:270683</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">PMC133916P2 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=270687%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=4261&link_uid=270687">UniSTS:270687</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">D1S1423 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=149619%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=4261&link_uid=149619">UniSTS:149619</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">PMC316580P8 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=273015%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=4261&link_uid=273015">UniSTS:273015</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">SHGC-67307 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=89991%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=4261&link_uid=89991">UniSTS:89991</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">SHGC-60649 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=37017%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=4261&link_uid=37017">UniSTS:37017</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">PMC125964P1 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=270517%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=4261&link_uid=270517">UniSTS:270517</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">STS-U18288 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=29661%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=4261&link_uid=29661">UniSTS:29661</a></li></ul></li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div></div>
|
||
|
||
<div class="infosec">
|
||
<h3 id="homology">
|
||
<a class="jig-ncbitoggler-open">Homology</a>
|
||
</h3>
|
||
<ul class="geneinfo-subsec">
|
||
<li>
|
||
<a href="/gene/4261/ortholog/" id="ncbi-ortholog-link">NCBI Orthologs</a>
|
||
</li>
|
||
<a href="https://www.orthodb.org/?ncbi=4261" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=8178" target="_blank">
|
||
Orthologs from OrthoDB
|
||
</a>
|
||
</ul>
|
||
</div>
|
||
|
||
<!--<component id="Gene_InfoPathway"/>-->
|
||
|
||
|
||
<div class="gene-ontology infosec">
|
||
<h3 id="gene-ontology">
|
||
<a class="jig-ncbitoggler-open">
|
||
<span>Gene Ontology</span>
|
||
</a>
|
||
<a target="_blank" href="http://www.ebi.ac.uk/GOA" class="g-ontology-src" title="Provided by GOA">Provided by GOA</a>
|
||
</h3>
|
||
<div class="ontology-tables">
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Function</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0004676">enables 3-phosphoinositide-dependent protein kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-1-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0004679">enables AMP-activated protein kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-2-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005524">enables ATP binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-3-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0003677">NOT enables DNA binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-4-0" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/15771576" target="_blank" title="PubMed ID 15771576" ref="ordinalpos=1&ncbi_uid=4261&link_uid=15771576">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0140297">enables DNA-binding transcription factor binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
|
||
<div id="evidence-code-5-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/9171108" target="_blank" title="PubMed ID 9171108" ref="ordinalpos=1&ncbi_uid=4261&link_uid=9171108">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0004677">enables DNA-dependent protein kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-6-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005525">enables GTP binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-7-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0072518">enables Rho-dependent protein serine/threonine kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-8-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-8-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0016746">enables acyltransferase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-9-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-9-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0004694">enables eukaryotic translation initiation factor 2alpha kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-10-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-10-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0044024">enables histone H2AS1 kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-11-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-11-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0072371">enables histone H2AS121 kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-12-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-12-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:1990244">enables histone H2AT120 kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-13-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-13-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0035979">enables histone H2AXS139 kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-14-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-14-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0044025">enables histone H2BS14 kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-15-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-15-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0140823">enables histone H2BS36 kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-16-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-16-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0035175">enables histone H3S10 kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-17-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-17-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0044022">enables histone H3S28 kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-18-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-18-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0140855">enables histone H3S57 kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-19-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-19-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0035402">enables histone H3T11 kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-20-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-20-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0072354">enables histone H3T3 kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-21-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-21-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0140857">enables histone H3T45 kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-22-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-22-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0035403">enables histone H3T6 kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-23-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-23-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0044023">enables histone H4S1 kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-24-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-24-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005515">enables protein binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-25-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
|
||
<div id="evidence-code-25-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/10938133,16600381,17493635,21890893,23007646" target="_blank" title="PubMed ID 10938133,16600381,17493635,21890893,23007646" ref="ordinalpos=1&ncbi_uid=4261&link_uid=10938133,16600381,17493635,21890893,23007646">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0106310">enables protein serine kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-26-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-26-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0044877">enables protein-containing complex binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-27-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-27-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/17493635" target="_blank" title="PubMed ID 17493635" ref="ordinalpos=1&ncbi_uid=4261&link_uid=17493635">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0004711">enables ribosomal protein S6 kinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-28-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-28-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0000976">enables transcription cis-regulatory region binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-29-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-29-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/19041327" target="_blank" title="PubMed ID 19041327" ref="ordinalpos=1&ncbi_uid=4261&link_uid=19041327">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0003713">enables transcription coactivator activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-30-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-30-0" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/7749984" target="_blank" title="PubMed ID 7749984" ref="ordinalpos=1&ncbi_uid=4261&link_uid=7749984">PubMed</a> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Process</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0006338">involved_in chromatin remodeling</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-1-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0046597">involved_in host-mediated suppression of symbiont invasion</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-2-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/32855215" target="_blank" title="PubMed ID 32855215" ref="ordinalpos=1&ncbi_uid=4261&link_uid=32855215">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0006955">involved_in immune response</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-3-1" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/8402893" target="_blank" title="PubMed ID 8402893" ref="ordinalpos=1&ncbi_uid=4261&link_uid=8402893">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0045892">involved_in negative regulation of DNA-templated transcription</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-4-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/19041327" target="_blank" title="PubMed ID 19041327" ref="ordinalpos=1&ncbi_uid=4261&link_uid=19041327">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0032966">involved_in negative regulation of collagen biosynthetic process</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IC</a>
|
||
<div id="evidence-code-5-1" class="ecode">Inferred by Curator<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/19041327" target="_blank" title="PubMed ID 19041327" ref="ordinalpos=1&ncbi_uid=4261&link_uid=19041327">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0000122">involved_in negative regulation of transcription by RNA polymerase II</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
|
||
<div id="evidence-code-6-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/19041327" target="_blank" title="PubMed ID 19041327" ref="ordinalpos=1&ncbi_uid=4261&link_uid=19041327">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0045893">involved_in positive regulation of DNA-templated transcription</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-7-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/19041327" target="_blank" title="PubMed ID 19041327" ref="ordinalpos=1&ncbi_uid=4261&link_uid=19041327">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0045345">involved_in positive regulation of MHC class I biosynthetic process</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-8-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-8-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0045345">involved_in positive regulation of MHC class I biosynthetic process</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-9-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-9-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/20639463" target="_blank" title="PubMed ID 20639463" ref="ordinalpos=1&ncbi_uid=4261&link_uid=20639463">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0045348">involved_in positive regulation of MHC class II biosynthetic process</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-10-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-10-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0045348">involved_in positive regulation of MHC class II biosynthetic process</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-11-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IC</a>
|
||
<div id="evidence-code-11-1" class="ecode">Inferred by Curator<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/9171108" target="_blank" title="PubMed ID 9171108" ref="ordinalpos=1&ncbi_uid=4261&link_uid=9171108">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0045944">involved_in positive regulation of transcription by RNA polymerase II</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-12-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-12-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0045944">involved_in positive regulation of transcription by RNA polymerase II</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-13-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-13-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/20639463,32855215" target="_blank" title="PubMed ID 20639463,32855215" ref="ordinalpos=1&ncbi_uid=4261&link_uid=20639463,32855215">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0045944">involved_in positive regulation of transcription by RNA polymerase II</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-14-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
|
||
<div id="evidence-code-14-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/9171108" target="_blank" title="PubMed ID 9171108" ref="ordinalpos=1&ncbi_uid=4261&link_uid=9171108">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0046677">acts_upstream_of_or_within response to antibiotic</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-15-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-15-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/107465" target="_blank" title="PubMed ID 107465" ref="ordinalpos=1&ncbi_uid=4261&link_uid=107465">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0034341">involved_in response to type II interferon</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-16-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-16-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/19041327,32855215" target="_blank" title="PubMed ID 19041327,32855215" ref="ordinalpos=1&ncbi_uid=4261&link_uid=19041327,32855215">PubMed</a> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-config="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Component</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0016605">located_in PML body</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-1-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/23007646" target="_blank" title="PubMed ID 23007646" ref="ordinalpos=1&ncbi_uid=4261&link_uid=23007646">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005829">located_in cytosol</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-2-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005654">located_in nucleoplasm</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-3-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005654">located_in nucleoplasm</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-4-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-general-protein-info">
|
||
<section class="rprt-section-header" id="general-protein-info">
|
||
<h2 id="header-general-protein-info">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-protein-info .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">General protein information</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.General_Protein_Information" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<dl>
|
||
<dt>Preferred Names</dt>
|
||
<dd>MHC class II transactivator</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt>Names</dt>
|
||
<dd>MHC class II transactivator type I</dd>
|
||
<dd>MHC class II transactivator type III</dd>
|
||
<dd>NLR family, acid domain containing</dd>
|
||
<dd>nucleotide-binding oligomerization domain, leucine rich repeat and acid domain containing</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">NP_000237.2</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">NP_001273331.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">NP_001273332.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">NP_001366259.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">NP_001366260.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">NP_001366261.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">NP_001366262.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">NP_001366263.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_006720943.2</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_011520786.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_011520787.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_011520788.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_011520792.2</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_011520793.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047290070.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047290071.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047290072.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047290073.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047290074.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047290075.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047290076.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047290078.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047290079.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047290080.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047290081.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047290082.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047290083.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_047290084.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054236303.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054236304.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054236305.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054236306.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054236307.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054236308.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054236309.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054236310.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054236311.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054236312.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054236313.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054236314.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054236315.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054236316.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054236317.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054236318.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054236319.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054236320.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054236321.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">XP_054236322.1</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-reference-sequences">
|
||
<section class="rprt-section-header" id="reference-sequences">
|
||
<h2 id="header-reference-sequences">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-reference-sequences .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">NCBI Reference Sequences (RefSeq)</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.NCBI_Reference_Sequences_RefS" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<p>
|
||
<span class="new-icon">NEW</span>
|
||
<strong>Try the new <a href="/datasets/tables/genes/?table_type=transcripts&ids=4261&utm_source=gene&utm_medium=referral&utm_campaign=refseq" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report." data-ga-category="refseq" data-ga-action="click_datasets_link" data-ga-label="transcript_table">Transcript table</a></strong>
|
||
</p>
|
||
<h3 class="genomerefseqs gene_std_toggler" id="refseqset-independent">
|
||
<a class="jig-ncbitoggler-open">RefSeqs maintained independently of Annotated
|
||
Genomes</a>
|
||
</h3>
|
||
<div class="genomerefseqs_slave">
|
||
<p class="desc"> These reference sequences exist independently of genome builds. <a href="#refseq-expl" id="expl-refseg">Explain</a></p>
|
||
<p id="refseq-expl"> These reference sequences are curated independently of the genome
|
||
annotation cycle, so their versions may not match the RefSeq versions in the current
|
||
genome build. Identify version mismatches by comparing the version of the RefSeq in
|
||
this section to the one reported in <a href="#geneGenomic regions, transcripts, and products">Genomic regions,
|
||
transcripts, and products</a> above. </p>
|
||
<h4 id="genomic-p19760432">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NG_009628.1 RefSeqGene</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>5001..52786</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NG_009628.1?from=5001&to=52786&report=genbank" ref="ordinalpos=1&ncbi_uid=4261&link_uid=NG_009628.1?from=5001&to=52786&report=genbank">GenBank</a>, <a href="/nuccore/NG_009628.1?from=5001&to=52786&report=fasta" ref="ordinalpos=1&ncbi_uid=4261&link_uid=NG_009628.1?from=5001&to=52786&report=fasta">FASTA</a>, <a href="/nuccore/NG_009628.1?from=1&to=59953&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=4261&link_uid=NG_009628.1?from=1&to=59953&report=graph&content=5">Sequence Viewer (Graphics)</a>, <a href="ftp://ftp.ebi.ac.uk/pub/databases/lrgex/LRG_49.xml">LRG_49</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="mrnaandproteins-p36877120">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/NM_000246.4">NM_000246.4</a> → <a href="/protein/NP_000237.2">NP_000237.2</a> MHC class II transactivator isoform 2</p>
|
||
<p>
|
||
<a href="/ipg/NP_000237.2/" ref="ncbi_uid=4261">See identical proteins and their annotated locations for NP_000237.2</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (2) is 1 aa shorter compared to isoform 1.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC133065, KF459560">AC133065, KF459560</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS10544.1">CCDS10544.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A0B4J1S1" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0A0B4J1S1</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000316328.8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">ENSP00000316328.8</a>, <a href="http://www.ensembl.org/id/ENST00000324288.14" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">ENST00000324288.14</a></dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_000237.2">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238064">cd00116</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">789</span> → <span class="cddto">1114</span></dt>
|
||
<dd class="clearfix"> LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275378">sd00031</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">989</span> → <span class="cddto">1016</span></dt>
|
||
<dd class="clearfix"> LRR_1; leucine-rich repeat [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275381">sd00034</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1071</span> → <span class="cddto">1101</span></dt>
|
||
<dd class="clearfix"> LRR_AMN1; leucine-rich repeat [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=399032">pfam05729</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">414</span> → <span class="cddto">583</span></dt>
|
||
<dd class="clearfix"> NACHT; NACHT domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001286402.1">NM_001286402.1</a> → <a href="/protein/NP_001273331.1">NP_001273331.1</a> MHC class II transactivator isoform 1</p>
|
||
<p>
|
||
<a href="/ipg/NP_001273331.1/" ref="ncbi_uid=4261">See identical proteins and their annotated locations for NP_001273331.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC133065, BC007406, BE247223, BM193016">AC133065, BC007406, BE247223, BM193016</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS73826.1">CCDS73826.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A087X2I7" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0A087X2I7</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000485010.1" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">ENSP00000485010.1</a>, <a href="http://www.ensembl.org/id/ENST00000618327.4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">ENST00000618327.4</a></dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001273331.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238064">cd00116</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">790</span> → <span class="cddto">1115</span></dt>
|
||
<dd class="clearfix"> LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275378">sd00031</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">990</span> → <span class="cddto">1017</span></dt>
|
||
<dd class="clearfix"> LRR_1; leucine-rich repeat [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275381">sd00034</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1072</span> → <span class="cddto">1102</span></dt>
|
||
<dd class="clearfix"> LRR_AMN1; leucine-rich repeat [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=399032">pfam05729</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">415</span> → <span class="cddto">584</span></dt>
|
||
<dd class="clearfix"> NACHT; NACHT domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001286403.2">NM_001286403.2</a> → <a href="/protein/NP_001273332.1">NP_001273332.1</a> MHC class II transactivator isoform 3</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (3) uses two alternate splice junctions and lacks two alternate coding exons compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter compared to isoform 1.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC133065, AY084054, BC007406, BE247223, BM193016">AC133065, AY084054, BC007406, BE247223, BM193016</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS66943.1">CCDS66943.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000371257.5" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">ENSP00000371257.5</a>, <a href="http://www.ensembl.org/id/ENST00000381835.9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">ENST00000381835.9</a></dd>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001273332.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238064">cd00116</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">299</span> → <span class="cddto">530</span></dt>
|
||
<dd class="clearfix"> LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275381">sd00034</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">402</span> → <span class="cddto">429</span></dt>
|
||
<dd class="clearfix"> LRR_AMN1; leucine-rich repeat [structural motif]</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001379330.1">NM_001379330.1</a> → <a href="/protein/NP_001366259.1">NP_001366259.1</a> MHC class II transactivator isoform 4</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC133065">AC133065</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001366259.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238064">cd00116</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">741</span> → <span class="cddto">1066</span></dt>
|
||
<dd class="clearfix"> LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275378">sd00031</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">941</span> → <span class="cddto">968</span></dt>
|
||
<dd class="clearfix"> LRR_1; leucine-rich repeat [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275381">sd00034</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1023</span> → <span class="cddto">1053</span></dt>
|
||
<dd class="clearfix"> LRR_AMN1; leucine-rich repeat [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=399032">pfam05729</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">366</span> → <span class="cddto">535</span></dt>
|
||
<dd class="clearfix"> NACHT; NACHT domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001379331.1">NM_001379331.1</a> → <a href="/protein/NP_001366260.1">NP_001366260.1</a> MHC class II transactivator isoform 5</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC133065">AC133065</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001366260.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238064">cd00116</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">740</span> → <span class="cddto">1065</span></dt>
|
||
<dd class="clearfix"> LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275378">sd00031</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">940</span> → <span class="cddto">967</span></dt>
|
||
<dd class="clearfix"> LRR_1; leucine-rich repeat [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275381">sd00034</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1022</span> → <span class="cddto">1052</span></dt>
|
||
<dd class="clearfix"> LRR_AMN1; leucine-rich repeat [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=399032">pfam05729</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">365</span> → <span class="cddto">534</span></dt>
|
||
<dd class="clearfix"> NACHT; NACHT domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001379332.1">NM_001379332.1</a> → <a href="/protein/NP_001366261.1">NP_001366261.1</a> MHC class II transactivator isoform 1</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC133065, KF459560">AC133065, KF459560</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS73826.1">CCDS73826.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A087X2I7" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0A087X2I7</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001366261.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238064">cd00116</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">790</span> → <span class="cddto">1115</span></dt>
|
||
<dd class="clearfix"> LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275378">sd00031</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">990</span> → <span class="cddto">1017</span></dt>
|
||
<dd class="clearfix"> LRR_1; leucine-rich repeat [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275381">sd00034</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1072</span> → <span class="cddto">1102</span></dt>
|
||
<dd class="clearfix"> LRR_AMN1; leucine-rich repeat [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=399032">pfam05729</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">415</span> → <span class="cddto">584</span></dt>
|
||
<dd class="clearfix"> NACHT; NACHT domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001379333.1">NM_001379333.1</a> → <a href="/protein/NP_001366262.1">NP_001366262.1</a> MHC class II transactivator isoform 2</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC133065, KF459560">AC133065, KF459560</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS10544.1">CCDS10544.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A0B4J1S1" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0A0B4J1S1</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001366262.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238064">cd00116</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">789</span> → <span class="cddto">1114</span></dt>
|
||
<dd class="clearfix"> LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275378">sd00031</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">989</span> → <span class="cddto">1016</span></dt>
|
||
<dd class="clearfix"> LRR_1; leucine-rich repeat [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275381">sd00034</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1071</span> → <span class="cddto">1101</span></dt>
|
||
<dd class="clearfix"> LRR_AMN1; leucine-rich repeat [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=399032">pfam05729</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">414</span> → <span class="cddto">583</span></dt>
|
||
<dd class="clearfix"> NACHT; NACHT domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001379334.1">NM_001379334.1</a> → <a href="/protein/NP_001366263.1">NP_001366263.1</a> MHC class II transactivator isoform 6</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC133065, KF459560">AC133065, KF459560</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001366263.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238064">cd00116</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">766</span> → <span class="cddto">1091</span></dt>
|
||
<dd class="clearfix"> LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275381">sd00034</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">963</span> → <span class="cddto">990</span></dt>
|
||
<dd class="clearfix"> LRR_AMN1; leucine-rich repeat [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=399032">pfam05729</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">391</span> → <span class="cddto">560</span></dt>
|
||
<dd class="clearfix"> NACHT; NACHT domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="rna-p133791664">RNA</h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/NR_104444.2">NR_104444.2</a> RNA Sequence </p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (4) uses an alternate splice junction and lacks an alternate exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC133065, AY084054, BC007406, BE247223, BM193016, U31931, X74301">AC133065, AY084054, BC007406, BE247223, BM193016, U31931, X74301</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
<h3 class="genomerefseqs gene_std_toggler" id="annotatedrefseq-title">
|
||
<a class="jig-ncbitoggler-open">RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08</a>
|
||
</h3>
|
||
<div class="genomerefseqs_slave">
|
||
<p class="desc"> The following sections contain reference sequences that belong to a
|
||
specific genome build. <a href="#" id="expl-genomes">Explain</a></p>
|
||
<p id="expl-genomes-desc" style="display:none">This section includes genomic Reference
|
||
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
|
||
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
|
||
assemblies. Model RNAs and proteins are also reported here.</p>
|
||
<h3 id="refseq-sequencedescription-p32895232">Reference GRCh38.p14 Primary Assembly</h3>
|
||
<h4 id="genomic-p32895232">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NC_000016.10 Reference GRCh38.p14 Primary Assembly</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>10866206..10943021</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NC_000016.10?from=10866206&to=10943021&report=genbank" ref="ordinalpos=1&ncbi_uid=4261&link_uid=NC_000016.10?from=10866206&to=10943021&report=genbank">GenBank</a>, <a href="/nuccore/NC_000016.10?from=10866206&to=10943021&report=fasta" ref="ordinalpos=1&ncbi_uid=4261&link_uid=NC_000016.10?from=10866206&to=10943021&report=fasta">FASTA</a>, <a href="/nuccore/NC_000016.10?from=10854683&to=10954542&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=4261&link_uid=NC_000016.10?from=10854683&to=10954542&report=graph&content=5">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="mrnaandproteins-p10185488">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011522485.3">XM_011522485.3</a> → <a href="/protein/XP_011520787.1">XP_011520787.1</a> MHC class II transactivator isoform X1</p>
|
||
<p>
|
||
<a href="/ipg/XP_011520787.1/" ref="ncbi_uid=4261">See identical proteins and their annotated locations for XP_011520787.1</a>
|
||
</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011520787.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238064">cd00116</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">888</span> → <span class="cddto">1213</span></dt>
|
||
<dd class="clearfix"> LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275381">sd00034</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1085</span> → <span class="cddto">1112</span></dt>
|
||
<dd class="clearfix"> LRR_AMN1; leucine-rich repeat [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=283404">pfam05729</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">513</span> → <span class="cddto">682</span></dt>
|
||
<dd class="clearfix"> NACHT; NACHT domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011522484.4">XM_011522484.4</a> → <a href="/protein/XP_011520786.1">XP_011520786.1</a> MHC class II transactivator isoform X1</p>
|
||
<p>
|
||
<a href="/ipg/XP_011520786.1/" ref="ncbi_uid=4261">See identical proteins and their annotated locations for XP_011520786.1</a>
|
||
</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011520786.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238064">cd00116</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">888</span> → <span class="cddto">1213</span></dt>
|
||
<dd class="clearfix"> LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275381">sd00034</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1085</span> → <span class="cddto">1112</span></dt>
|
||
<dd class="clearfix"> LRR_AMN1; leucine-rich repeat [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=283404">pfam05729</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">513</span> → <span class="cddto">682</span></dt>
|
||
<dd class="clearfix"> NACHT; NACHT domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_006720880.4">XM_006720880.4</a> → <a href="/protein/XP_006720943.2">XP_006720943.2</a> MHC class II transactivator isoform X1</p>
|
||
<p>
|
||
<a href="/ipg/XP_006720943.2/" ref="ncbi_uid=4261">See identical proteins and their annotated locations for XP_006720943.2</a>
|
||
</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_006720943.2">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238064">cd00116</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">888</span> → <span class="cddto">1213</span></dt>
|
||
<dd class="clearfix"> LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275381">sd00034</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1085</span> → <span class="cddto">1112</span></dt>
|
||
<dd class="clearfix"> LRR_AMN1; leucine-rich repeat [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=283404">pfam05729</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">513</span> → <span class="cddto">682</span></dt>
|
||
<dd class="clearfix"> NACHT; NACHT domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047434123.1">XM_047434123.1</a> → <a href="/protein/XP_047290079.1">XP_047290079.1</a> MHC class II transactivator isoform X5</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011522486.3">XM_011522486.3</a> → <a href="/protein/XP_011520788.1">XP_011520788.1</a> MHC class II transactivator isoform X2</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011520788.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238064">cd00116</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">888</span> → <span class="cddto">1149</span></dt>
|
||
<dd class="clearfix"> LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275378">sd00031</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1088</span> → <span class="cddto">1115</span></dt>
|
||
<dd class="clearfix"> LRR_1; leucine-rich repeat [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=283404">pfam05729</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">513</span> → <span class="cddto">682</span></dt>
|
||
<dd class="clearfix"> NACHT; NACHT domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011522491.3">XM_011522491.3</a> → <a href="/protein/XP_011520793.1">XP_011520793.1</a> MHC class II transactivator isoform X7</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011520793.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238064">cd00116</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">888</span> → <span class="cddto">1119</span></dt>
|
||
<dd class="clearfix"> LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=283404">pfam05729</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">513</span> → <span class="cddto">682</span></dt>
|
||
<dd class="clearfix"> NACHT; NACHT domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047434115.1">XM_047434115.1</a> → <a href="/protein/XP_047290071.1">XP_047290071.1</a> MHC class II transactivator isoform X4</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047434118.1">XM_047434118.1</a> → <a href="/protein/XP_047290074.1">XP_047290074.1</a> MHC class II transactivator isoform X6</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047434114.1">XM_047434114.1</a> → <a href="/protein/XP_047290070.1">XP_047290070.1</a> MHC class II transactivator isoform X3</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047434120.1">XM_047434120.1</a> → <a href="/protein/XP_047290076.1">XP_047290076.1</a> MHC class II transactivator isoform X8</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A087X2I7" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0A087X2I7</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047434122.1">XM_047434122.1</a> → <a href="/protein/XP_047290078.1">XP_047290078.1</a> MHC class II transactivator isoform X9</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A0B4J1S1" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0A0B4J1S1</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047434128.1">XM_047434128.1</a> → <a href="/protein/XP_047290084.1">XP_047290084.1</a> MHC class II transactivator isoform X11</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047434126.1">XM_047434126.1</a> → <a href="/protein/XP_047290082.1">XP_047290082.1</a> MHC class II transactivator isoform X10</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047434127.1">XM_047434127.1</a> → <a href="/protein/XP_047290083.1">XP_047290083.1</a> MHC class II transactivator isoform X11</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047434117.1">XM_047434117.1</a> → <a href="/protein/XP_047290073.1">XP_047290073.1</a> MHC class II transactivator isoform X5</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047434116.1">XM_047434116.1</a> → <a href="/protein/XP_047290072.1">XP_047290072.1</a> MHC class II transactivator isoform X5</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047434124.1">XM_047434124.1</a> → <a href="/protein/XP_047290080.1">XP_047290080.1</a> MHC class II transactivator isoform X4</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047434125.1">XM_047434125.1</a> → <a href="/protein/XP_047290081.1">XP_047290081.1</a> MHC class II transactivator isoform X4</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047434119.1">XM_047434119.1</a> → <a href="/protein/XP_047290075.1">XP_047290075.1</a> MHC class II transactivator isoform X3</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011522490.3">XM_011522490.3</a> → <a href="/protein/XP_011520792.2">XP_011520792.2</a> MHC class II transactivator isoform X3</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="rna-p88660368">RNA</h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/XR_001751904.2">XR_001751904.2</a> RNA Sequence </p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XR_007064880.1">XR_007064880.1</a> RNA Sequence </p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XR_007064879.1">XR_007064879.1</a> RNA Sequence </p>
|
||
<dl></dl>
|
||
</li>
|
||
</ol>
|
||
<h3 id="refseq-sequencedescription-p102746336">Alternate T2T-CHM13v2.0</h3>
|
||
<h4 id="genomic-p102746336">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NC_060940.1 Alternate T2T-CHM13v2.0</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>10902173..10978992</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NC_060940.1?from=10902173&to=10978992&report=genbank" ref="ordinalpos=1&ncbi_uid=4261&link_uid=NC_060940.1?from=10902173&to=10978992&report=genbank">GenBank</a>, <a href="/nuccore/NC_060940.1?from=10902173&to=10978992&report=fasta" ref="ordinalpos=1&ncbi_uid=4261&link_uid=NC_060940.1?from=10902173&to=10978992&report=fasta">FASTA</a>, <a href="/nuccore/NC_060940.1?from=10890649&to=10990514&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=4261&link_uid=NC_060940.1?from=10890649&to=10990514&report=graph&content=5">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="mrnaandproteins-p138195056">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054380331.1">XM_054380331.1</a> → <a href="/protein/XP_054236306.1">XP_054236306.1</a> MHC class II transactivator isoform X2</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054380339.1">XM_054380339.1</a> → <a href="/protein/XP_054236314.1">XP_054236314.1</a> MHC class II transactivator isoform X7</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054380330.1">XM_054380330.1</a> → <a href="/protein/XP_054236305.1">XP_054236305.1</a> MHC class II transactivator isoform X1</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054380329.1">XM_054380329.1</a> → <a href="/protein/XP_054236304.1">XP_054236304.1</a> MHC class II transactivator isoform X1</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054380328.1">XM_054380328.1</a> → <a href="/protein/XP_054236303.1">XP_054236303.1</a> MHC class II transactivator isoform X1</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054380342.1">XM_054380342.1</a> → <a href="/protein/XP_054236317.1">XP_054236317.1</a> MHC class II transactivator isoform X5</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054380333.1">XM_054380333.1</a> → <a href="/protein/XP_054236308.1">XP_054236308.1</a> MHC class II transactivator isoform X4</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054380336.1">XM_054380336.1</a> → <a href="/protein/XP_054236311.1">XP_054236311.1</a> MHC class II transactivator isoform X6</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054380332.1">XM_054380332.1</a> → <a href="/protein/XP_054236307.1">XP_054236307.1</a> MHC class II transactivator isoform X3</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054380340.1">XM_054380340.1</a> → <a href="/protein/XP_054236315.1">XP_054236315.1</a> MHC class II transactivator isoform X8</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054380341.1">XM_054380341.1</a> → <a href="/protein/XP_054236316.1">XP_054236316.1</a> MHC class II transactivator isoform X9</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054380347.1">XM_054380347.1</a> → <a href="/protein/XP_054236322.1">XP_054236322.1</a> MHC class II transactivator isoform X11</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054380345.1">XM_054380345.1</a> → <a href="/protein/XP_054236320.1">XP_054236320.1</a> MHC class II transactivator isoform X10</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054380346.1">XM_054380346.1</a> → <a href="/protein/XP_054236321.1">XP_054236321.1</a> MHC class II transactivator isoform X11</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A0N0N9" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">A0N0N9</a>, <a href="https://www.uniprot.org/uniprot/D3DUG0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">D3DUG0</a>, <a href="https://www.uniprot.org/uniprot/E9PFE0" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">E9PFE0</a>, <a href="https://www.uniprot.org/uniprot/P33076" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">P33076</a>, <a href="https://www.uniprot.org/uniprot/Q29675" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q29675</a>, <a href="https://www.uniprot.org/uniprot/Q8SNB8" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q8SNB8</a>, <a href="https://www.uniprot.org/uniprot/Q96KL4" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q96KL4</a></dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054380335.1">XM_054380335.1</a> → <a href="/protein/XP_054236310.1">XP_054236310.1</a> MHC class II transactivator isoform X5</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054380334.1">XM_054380334.1</a> → <a href="/protein/XP_054236309.1">XP_054236309.1</a> MHC class II transactivator isoform X5</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054380343.1">XM_054380343.1</a> → <a href="/protein/XP_054236318.1">XP_054236318.1</a> MHC class II transactivator isoform X4</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054380344.1">XM_054380344.1</a> → <a href="/protein/XP_054236319.1">XP_054236319.1</a> MHC class II transactivator isoform X4</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054380337.1">XM_054380337.1</a> → <a href="/protein/XP_054236312.1">XP_054236312.1</a> MHC class II transactivator isoform X3</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054380338.1">XM_054380338.1</a> → <a href="/protein/XP_054236313.1">XP_054236313.1</a> MHC class II transactivator isoform X3</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q66X48" ref="itool=Gene_FullReport&PrId=5380&uid=4261&nlmid=&db=gene">Q66X48</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="rna-p140371200">RNA</h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/XR_008489092.1">XR_008489092.1</a> RNA Sequence </p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XR_008489093.1">XR_008489093.1</a> RNA Sequence </p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XR_008489091.1">XR_008489091.1</a> RNA Sequence </p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XR_008489090.1">XR_008489090.1</a> RNA Sequence </p>
|
||
<dl></dl>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-related-sequences">
|
||
<section class="rprt-section-header" id="related-sequences">
|
||
<h2 id="header-related-sequences">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-related-sequences .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Related sequences</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Related_Sequences" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<table id="proteinTblId" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/4261/data/related-sequences/',webserviceParams: 'p$l=Ajax', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th colspan="2" id="rs-nucleo">Nucleotide</th>
|
||
<th rowspan="2" id="rs-protein">Protein</th>
|
||
</tr>
|
||
<tr>
|
||
<th id="rs-heading">Heading</th>
|
||
<th id="rs-heading-acc">Accession and Version</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody></tbody>
|
||
</table>
|
||
<table id="proteinTblId" class="jig-ncbigrid" data-jigconfig="isPageable:true, pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th class="proteinTblTh" rowspan="2" id="rs-prot-acc">Protein Accession</th>
|
||
<th class="proteinTblTh" colspan="2" id="rs-link">Links</th>
|
||
</tr>
|
||
<tr>
|
||
<th id="rs-genepept">GenPept Link</th>
|
||
<th id="rs-uniprot">UniProtKB Link</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="rs-prot-acc">P33076.3</td>
|
||
<td headers="rs-link rs-genepept">
|
||
<a href="/protein/317373472" ref="ordinalpos=1&ncbi_uid=4261&link_uid=317373472">GenPept</a>
|
||
</td>
|
||
<td>
|
||
<a href="https://www.uniprot.org/uniprot/P33076">UniProtKB/Swiss-Prot:P33076</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-additional-links">
|
||
|
||
<section class="rprt-section-header" id="additional-links"><h2 id="header-additional-links"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-additional-links .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Additional links</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Additional_Links" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
|
||
|
||
<div class="rprt-section-body" style="">
|
||
<div id="lsdb"><h3 class="withnote" id="locusspecificdatabases"><a class="jig-ncbitoggler-open">Locus-specific Databases</a></h3><div><ul class="locusdb"><li><a href="http://structure.bmc.lu.se/idbase/CIITAbase/" ref="from_uid=4261" class="lsdblink">CIITAbase: Mutation registry for MHCII transactivating protein deficiency (previously known as MHC2TAbase)</a></li><li><a href="http://databases.lovd.nl/shared/genes/CIITA" ref="from_uid=4261" class="lsdblink">CIITA database</a></li></ul></div></div>
|
||
|
||
<h3 class="withnote" id="genelinkout">
|
||
<a class="jig-ncbitoggler">Gene LinkOut</a>
|
||
</h3><div>
|
||
<p>The following <a href="https://www.ncbi.nlm.nih.gov/projects/linkout/index.html">LinkOut</a> resources are supplied by external providers. These providers are responsible for maintaining the links. </p>
|
||
<div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Chemical Information</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Interologous Interaction Database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://ophid.utoronto.ca/redirect/ncbi/human?proteins=4261" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=7911">
|
||
<span>Interologous Interaction Database</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>MilliporeSigma</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.sigmaaldrich.com/catalog/genes/CIITA?lang=en&region=US" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=9978">
|
||
<span>CIITA products</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Medical</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>MedlinePlus Health Information</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://medlineplus.gov/genetics/gene/ciita" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=3162">
|
||
<span>CIITA gene</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Molecular Biology Databases</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Bgee database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.bgee.org/gene/ENSG00000179583" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=10418">
|
||
<span>CIITA gene expression</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>BioGPS</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://biogps.org/gene/4261/" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=5059">
|
||
<span>BioGPS</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>BioGRID Open Repository of CRISPR Screens (ORCS)</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://orcs.thebiogrid.org/Gene/4261" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=10164">
|
||
<span>BioGRID CRISPR Screen Phenotypes (19 hits/1359 screens)</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Domain Mapping of Disease Mutations</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://bioinf.umbc.edu/DMDM/gene_prot_page.php?id=4261" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=7642">
|
||
<span>CIITA</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Eukaryotic Promoter Database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://epd.vital-it.ch/cgi-bin/get_doc?db=hgEpdNew&format=genome&entry=CIITA_1" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=9624">
|
||
<span>CIITA_1</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>GlyGen glycoinformatics resource</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://glygen.org/protein/P33076" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=10227">
|
||
<span>GlyGen glycoinformatics resource</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Guide to Pharmacology</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=1767" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=8191">
|
||
<span>CIITA gene</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span><span class="regis-rsc"></span>Human Gene Mutation Database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.hgmd.cf.ac.uk/ac/gene.php?gene=CIITA" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=3100">
|
||
<span>Human Gene Mutation Database</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Human eFP Browser</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Reproductive&modeInput=Absolute&primaryGene=4261" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Skeletal_Immune_Digestive&modeInput=Absolute&primaryGene=4261" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Circulatory_Respiratory&modeInput=Absolute&primaryGene=4261" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li>Ingenuity Pathways Analysis</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://partnersolution.ingenuity.com/?cid=97ae3f91eab87a&p1=Entrez&p2=GV&s=&ipaUri=%2Fpa%2Fapi%2Fv2%2Fgeneview%3Fapplicationname%3DEntrez%26geneId%3D4261%26geneidtype%3Dentrezgene" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=5628">
|
||
<span>Ingenuity Pathways Analysis</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>InnateDB</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.innatedb.com/getGeneCard.do?id=14377" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=7894">
|
||
<span>InnateDB</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>InterMine</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.humanmine.org/humanmine/search?keyword=ENSG00000179583" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=9169">
|
||
<span>InterMine</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Kyoto Encyclopedia of Genes and Genomes</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.genome.jp/dbget-bin/www_bget?hsa:4261" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=5174">
|
||
<span>Kyoto Encyclopedia of Genes and Genomes</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>OMA Browser: Orthologous MAtrix</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN26614/" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN26613/" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN26612/" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>OrthoDB catalog of orthologs</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.orthodb.org/?ncbi=4261" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=8178">
|
||
<span>Orthologs</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>PhosphoSitePlus</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.phosphosite.org/entrezGeneIdAction.action?id=4261" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=7987">
|
||
<span>PhosphoSitePlus® - comprehensive post-translational modification resource</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>The Gene Wiki</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://en.wikipedia.org/wiki/CIITA" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=6933">
|
||
<span>The Gene Wiki</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>The Weizmann Institute of Science GeneCards and MalaCards databases</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=CIITA" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=8598">
|
||
<span>GeneCard for CIITA</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Research Materials</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="order-rsc"></span>Addgene Non-profit plasmid repository</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://addgene.org//browse/gene/4261" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=5304">
|
||
<span>Get Plasmids - Addgene</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>Bio-Techne</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/ciita/lysates?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=lysates" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>CIITA Lysates</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/ciita/antibodies?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=antibodies" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>CIITA Antibodies</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/ciita/proteins-enzymes?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=proteins" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>CIITA Proteins</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>Creative Biogene</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.creative-biogene.com/genesearch/Ciita.html" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=10094">
|
||
<span>class II, major histocompatibility complex, transactivator</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li>ExactAntigen/Labome</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.labome.com/gene/human/CIITA-antibody.html" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=5753">
|
||
<span>reagents</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.labome.com/review/gene/human/CIITA-antibody.html" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=5753">
|
||
<span>reagent review</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GenScript latest version of gene cDNA ORF Clone</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.genscript.com/gene/4261" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=8012">
|
||
<span>GenScript latest version of gene cDNA ORF Clone</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GeneCopoeia Inc.</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=26&field=5&key=4261" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order TALEN/CRISPR clones</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?tax_id=9606&field=5&prt=16&key=4261" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order miRNA target clones</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=1&field=5&key=4261" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order full-length ORF clone</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GeneTex Inc</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genetex.com/Product/Search?geneid=4261&type=01&page=1" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=8117">
|
||
<span>Find Quality Antibodies</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>Kazusa DNA Research Institute</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.kazusa.or.jp/kop/dsearch/symsearch.cgi?keyword=C2TA;" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=3267">
|
||
<span>Kazusa DNA Research Institute</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>OriGene</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.origene.com/search?q=CIITA" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=7994">
|
||
<span>Order CIITA cDNA clone/Protein/Antibody/RNAi</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Tools</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>GeneMANIA</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://genemania.org/link?o=9606&g=4261" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=7529">
|
||
<span>GeneMANIA</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open">
|
||
<span>Miscellaneous</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Reactome</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://reactome.org/content/query?q=UniProt:P33076" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=4914">
|
||
<span>Reactome Entity:P33076</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://reactome.org/PathwayBrowser/#/R-HSA-168256" ref="itool=Gene_FullReport&uid=4261&nlmid=&db=gene&log$=linkoutlink&PrId=4914">
|
||
<span>Reactome Event:Immune System</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="urls-in-genombrowser" style="display:none">
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div><input type="hidden" class="section_status_input" name="status_checked" id="status_checked" value="" /><input type="hidden" class="section_status_input" name="status_open" id="status_open" value="summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links" /><input type="hidden" class="section_status_input" name="status_exist" id="status_exist" value="summary,context,region,expression,bibliography,phenotypes,variation,hiv,,interactions,geneInfo,proteinInfo,refSeq,related,links" /><input type="hidden" class="section_status_input" name="status_closed" id="status_closed" value="" /><meta name="status_checked" content="" class="meta_section_status" /><meta name="status_open" content="summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links" class="meta_section_status" /><meta name="status_exist" content="summary,context,region,expression,bibliography,phenotypes,variation,hiv,,interactions,geneInfo,proteinInfo,refSeq,related,links" class="meta_section_status" /><meta name="status_closed" content="" class="meta_section_status" /><script type="text/javascript">
|
||
|
||
var section_status_meta = {
|
||
'status_checked': '',
|
||
'status_open': 'summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links',
|
||
'status_exist': 'summary,context,region,expression,bibliography,phenotypes,variation,hiv,,interactions,geneInfo,proteinInfo,refSeq,related,links',
|
||
'status_closed': ''
|
||
};
|
||
|
||
|
||
/*
|
||
for (var o in section_status_meta) {
|
||
var meta=document.createElement('meta');
|
||
meta.name = o;
|
||
meta.content = section_status_meta[o];
|
||
var attr = document.createAttribute('data-ignore-limit');
|
||
attr.value = 'true';
|
||
meta.setAttributeNode(attr);
|
||
document.getElementsByTagName('head')[0].appendChild(meta);
|
||
}
|
||
*/
|
||
|
||
|
||
var __ncbi_sg_pingCallbacks_render_gene = function (data, evtObj, type) {
|
||
// data looks like {jsevent: "click", "link_id": "foo", ...}
|
||
// evtObj is the JS event object
|
||
// type is either "stat" (for applog) or "ga"
|
||
var extraData = {};
|
||
if (type == "stat") {
|
||
for (var o in section_status_meta) {
|
||
extraData[o] = section_status_meta[o];
|
||
}
|
||
|
||
return extraData;
|
||
|
||
}
|
||
}
|
||
|
||
|
||
</script></div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last" id="sidebar_tabular">
|
||
<!-- sidebar close/hide button-->
|
||
<div class="ui-helper-clearfix">
|
||
<a href="#" id="sidecontent_2_pullout" style="float:right;" class="sidecontentpullout_local collapse_button"><span>Hide sidebar >></span></a>
|
||
</div>
|
||
<!-- end sidebar close/hide button-->
|
||
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div id="gene-sidebar">
|
||
<div>
|
||
<div class="portlet brieflink dis-table-of-contents">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Table of contents</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_TableOfContents" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li class="">
|
||
<a href="#summary">Summary</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#genomic-context">Genomic context</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#genomic-regions-transcripts-products">Genomic regions, transcripts, and products</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#gene-expression">Expression</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#bibliography">Bibliography</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#phenotypes">Phenotypes</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#variation">Variation</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#HIV-1-interactions">HIV-1 interactions</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#pathways">Pathways from PubChem</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#interactions">Interactions</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#general-gene-info">General gene information</a>
|
||
<div class="subsection-links"><a href="#gene-markers">Markers</a>, <a href="#homology">Homology</a>, <a href="#gene-ontology">Gene Ontology</a></div>
|
||
</li>
|
||
<li class="">
|
||
<a href="#general-protein-info">General protein information</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#reference-sequences">NCBI Reference Sequences (RefSeq)</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#related-sequences">Related sequences</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#additional-links">Additional links</a>
|
||
<div class="subsection-links">
|
||
<a href="#lsdb">Locus-specific Databases</a>
|
||
</div>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-genomesbrowser brieflink dis-genomesbrowser">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Genome Browsers</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GenomeBrowsers.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_GenomeBrowsers" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GenomeBrowsers.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="#">Loading...</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet dis-related-info brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related information</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="discovery_db_links" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content DiscoveryDbLinks">
|
||
<ul>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clone/order/gene/4261" ref="log$=recordlinks">Order cDNA clone</a>
|
||
<div class="brieflinkpop offscreen_noflow">Order cDNA clone</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_alltarget_list&from_uid=4261" ref="log$=recordlinks">BioAssay by Target (List)</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioAssays related to the gene by protein target or RNAi target</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_target&from_uid=4261" ref="log$=recordlinks">BioAssay, by Gene target</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem BioAssays done on the Gene target</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_rnai&from_uid=4261" ref="log$=recordlinks">BioAssays, RNAi Target, Tested</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioAssays that contain the gene as the target of a RNAi reagent</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/bioproject?LinkName=gene_bioproject&from_uid=4261" ref="log$=recordlinks">BioProjects</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioProjects related to a gene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/biosystems?LinkName=gene_biosystems&from_uid=4261" ref="log$=recordlinks">BioSystems</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioSystems</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/CCDS/CcdsBrowse.cgi?REQUEST=GENEID&DATA=4261" ref="log$=recordlinks">CCDS</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to CCDS</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar&from_uid=4261" ref="log$=recordlinks">ClinVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/cdd?LinkName=gene_cdd&from_uid=4261" ref="log$=recordlinks">Conserved Domains</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related CDD</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/dbvar?LinkName=gene_dbvar&from_uid=4261" ref="log$=recordlinks">dbVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link from Gene to dbVar</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc&from_uid=4261" ref="log$=recordlinks">Full text in PMC</a>
|
||
<div class="brieflinkpop offscreen_noflow">PMC links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc_nucleotide&from_uid=4261" ref="log$=recordlinks">Full text in PMC_nucleotide</a>
|
||
<div class="brieflinkpop offscreen_noflow">Full text in PubMedCentral identified from shared sequence links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/sparcle?LinkName=gene_sparcle&from_uid=4261" ref="log$=recordlinks">Functional Class</a>
|
||
<div class="brieflinkpop offscreen_noflow">Functional class of the sequence domain architecture</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gap?LinkName=gene_gap&from_uid=4261" ref="log$=recordlinks">GAP</a>
|
||
<div class="brieflinkpop offscreen_noflow">GAP Links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_neighbors&from_uid=4261" ref="log$=recordlinks">Gene neighbors</a>
|
||
<div class="brieflinkpop offscreen_noflow">Overlapping genes and two nearest non-overlapping genes on either side</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_h3k4me3&from_uid=4261" ref="log$=recordlinks">Genes with a similar H3K4me3 profile</a>
|
||
<div class="brieflinkpop offscreen_noflow">Genes with a similar profile of promoter-activating H3K4me3 modifications across several tissue types</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/genome?LinkName=gene_genome&from_uid=4261" ref="log$=recordlinks">Genome</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Genome</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/geoprofiles?LinkName=gene_geoprofiles&from_uid=4261" ref="log$=recordlinks">GEO Profiles</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related GEO</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests/?term=4261[geneid]" ref="log$=recordlinks">GTR</a>
|
||
<div class="brieflinkpop offscreen_noflow">Tests for this gene in the NIH Genetic Testing Registry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/homologene?LinkName=gene_homologene&from_uid=4261" ref="log$=recordlinks">HomoloGene</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related HomoloGene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/medgen?LinkName=gene_medgen_diseases&from_uid=4261" ref="log$=recordlinks">MedGen</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related information in MedGen</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore&from_uid=4261" ref="log$=recordlinks">Nucleotide</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related Nucleotide entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/omim?LinkName=gene_omim&from_uid=4261" ref="log$=recordlinks">OMIM</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related OMIM entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/probe?LinkName=gene_probe&from_uid=4261" ref="log$=recordlinks">Probe</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Probe entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein&from_uid=4261" ref="log$=recordlinks">Protein</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related protein entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pccompound?LinkName=gene_pccompound&from_uid=4261" ref="log$=recordlinks">PubChem Compound</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem Compounds</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcsubstance?LinkName=gene_pcsubstance&from_uid=4261" ref="log$=recordlinks">PubChem Substance</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem Substances</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed&from_uid=4261" ref="log$=recordlinks">PubMed</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related PubMed entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_rif&from_uid=4261" ref="log$=recordlinks">PubMed (GeneRIF)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related PubMed article from GeneRIFs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_citedinomim&from_uid=4261" ref="log$=recordlinks">PubMed (OMIM)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Gene links to PubMed derived from omim_pubmed_cited links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_pmc_nucleotide&from_uid=4261" ref="log$=recordlinks">PubMed(nucleotide/PMC)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Citations in PubMed identified from shared sequence and PMC links.</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein_refseq&from_uid=4261" ref="log$=recordlinks">RefSeq Proteins</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Protein RefSeqs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore_refseqrna&from_uid=4261" ref="log$=recordlinks">RefSeq RNAs</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeq RNAs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore/223555946?report=graph" ref="log$=recordlinks">RefSeqGene</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeqGenes</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar_specific&from_uid=4261" ref="log$=recordlinks">Related gene-specific medical variations</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/snp?LinkName=gene_snp&from_uid=4261" ref="log$=recordlinks">SNP</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related SNP records</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/taxonomy?LinkName=gene_taxonomy&from_uid=4261" ref="log$=recordlinks">Taxonomy</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related taxonomy entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/variation/view/?q=4261[geneid]" ref="log$=recordlinks">Variation Viewer</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Variants</div>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet dis-links-to-other-res brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Links to other resources</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_LinksTwo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7067">HGNC</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.ensembl.org/id/ENSG00000179583">Ensembl</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.alliancegenome.org/gene/HGNC:7067">AllianceGenome</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=geneid&org=9606&l=4261">AceView</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://databases.lovd.nl/shared/genes/CIITA">CIITA database</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://structure.bmc.lu.se/idbase/CIITAbase/">CIITAbase: Mutation registry for MHCII transactivating protein deficiency (previously known as MHC2TAbase)</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position=NM_000246">UCSC</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://genecollections.nci.nih.gov/MGC/?ORG=Hs&LIST=BC172348">MGC</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://phgkb.cdc.gov/PHGKB/huGEPedia.action?firstQuery=CIITA&geneID=4261&typeOption=gene&which=2&pubOrderType=pubD&typeSubmit=GO&check=y">HuGE Navigator</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.genome.jp/dbget-bin/www_bget?hsa:4261">KEGG</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://reactome.org/content/query?q=UniProt:P33076">Reactome</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-general-info">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>General information</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_GeneralInfo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="/pmc/?term=PMC4383897+OR+PMC3013746+OR+PMC1761442+OR+PMC539985">About Gene</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3840">FAQ</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://ftp.ncbi.nlm.nih.gov/gene/">FTP site</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3841/">Help</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3842/">My NCBI help</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK21085/">NCBI Handbook</a>
|
||
</li>
|
||
<li>
|
||
<a href="/gene/statistics/">Statistics</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-related-sites">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related sites</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedSites.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_RelatedSites" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedSites.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/BLAST">BLAST</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/genome">Genome</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/bioproject">BioProject</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/genome/gdv/">Genome Data Viewer</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/geo">GEO</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/omim">OMIM</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/probe">Probe</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/RefSeq">RefSeq</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-feedback">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Feedback</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Feedback.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_Feedback" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Feedback.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://support.ncbi.nlm.nih.gov/ics/support/ticketnewwizard.asp?style=classic&deptID=28049">Contact Help Desk</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/RefSeq/update.cgi?geneid=4261&symbol=CIITA">Submit Correction</a>
|
||
</li>
|
||
<li>
|
||
<a href="/gene/submit-generif?geneId=4261&sym=CIITA&name=class II major histocompatibility complex transactivator&org=Homo sapiens">Submit GeneRIF</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-subscription">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Subscription</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Subscription.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_Subscription" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Subscription.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/mailman/listinfo/refseq-announce">RefSeq</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
<!-- <component id="Gene_RVFullReport.Gene_RightColMenuLinks"/>-->
|
||
<div class="portlet">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Recent activity</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="recent_activity" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<div id="HTDisplay" class="">
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.Cmd" sid="1" type="hidden" />
|
||
<div class="action">
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory" cmd="ClearHT" href="?cmd=ClearHT&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory">
|
||
Clear
|
||
</a>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOn" cmd="HTOff" href="?cmd=HTOff&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle">
|
||
Turn Off
|
||
</a>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" sid="2" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOff" cmd="HTOn" href="?cmd=HTOn&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle">
|
||
Turn On
|
||
</a>
|
||
</div>
|
||
<ul id="activity">
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67c9da5384f3725e59143a8d">CIITA class II major histocompatibility complex transactivator [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">CIITA class II major histocompatibility complex transactivator [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:4261</div></div>
|
||
<div class="tertiary">Gene</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=2" href="/portal/utils/pageresolver.fcgi?recordid=67c9da5184f3725e59142f6e">MHC class II transactivator isoform 2 [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">MHC class II transactivator isoform 2 [Homo sapiens]<div class="brieflinkpopdesc">gi|156938336|ref|NP_000237.2|</div></div>
|
||
<div class="tertiary">Protein</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=3" href="/portal/utils/pageresolver.fcgi?recordid=67c9da4fb15b832ebce7e568">CHUK component of inhibitor of nuclear factor kappa B kinase complex [Homo sapie...</a>
|
||
<div class="ralinkpop offscreen_noflow">CHUK component of inhibitor of nuclear factor kappa B kinase complex [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:1147</div></div>
|
||
<div class="tertiary">Gene</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=4" href="/portal/utils/pageresolver.fcgi?recordid=67c9da4db15b832ebce7db48">inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 [Homo sapiens...</a>
|
||
<div class="ralinkpop offscreen_noflow">inhibitor of nuclear factor kappa-B kinase subunit alpha isoform 1 [Homo sapiens]<div class="brieflinkpopdesc">gi|62241001|ref|NP_001269.3|</div></div>
|
||
<div class="tertiary">Protein</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=5" href="/portal/utils/pageresolver.fcgi?recordid=67c9da4ba68b6b5afc4d4269">neuronal acetylcholine receptor subunit beta-2 precursor [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">neuronal acetylcholine receptor subunit beta-2 precursor [Homo sapiens]<div class="brieflinkpopdesc">gi|4502833|ref|NP_000739.1|</div></div>
|
||
<div class="tertiary">Protein</div>
|
||
</li>
|
||
</ul>
|
||
<p class="HTOn">Your browsing activity is empty.</p>
|
||
<p class="HTOff">Activity recording is turned off.</p>
|
||
<p id="turnOn" class="HTOff">
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryOn" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryOn" cmd="HTOn" href="?cmd=HTOn&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryOn">Turn recording back on</a>
|
||
</p>
|
||
<a class="seemore" href="/sites/myncbi/recentactivity">See more...</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div id="NCBIFooter_dynamic">
|
||
<!--<component id="NCBIBreadcrumbs"/>
|
||
<component id="NCBIHelpDesk"/>-->
|
||
<noscript><img alt="" src="/stat?jsdisabled=true&ncbi_app=entrez&ncbi_db=gene&ncbi_pdid=full_report&ncbi_phid=CE8A29C47C9B95910000000000CE00B9" /></noscript>
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</div>
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<div xmlns="http://www.w3.org/1999/xhtml" class="footer" id="footer" xml:base="http://127.0.0.1/sites/static/header_footer/">
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<section class="icon-section">
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<div id="icon-section-header" class="icon-section_header">Follow NCBI</div>
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<div class="grid-container container">
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<div class="icon-section_container">
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<a class="footer-icon" id="footer_twitter" href="https://twitter.com/ncbi" aria-label="Twitter">
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<title>Twitter</title>
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<g id="twitterx1008">
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<path id="path1008" d="M6.06736 7L16.8778 20.8991L6.00001 32.2H10.2L18.6 23.1L25.668 32.2H34L22.8 17.5L31.9 7H28.4L20.7 15.4L14.401 7H6.06898H6.06736ZM9.66753 8.73423H12.9327L29.7327 30.4658H26.5697L9.66753 8.73423Z" fill="#5B616B"></path>
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<a class="footer-icon" id="footer_facebook" href="https://www.facebook.com/ncbi.nlm" aria-label="Facebook"><svg xmlns="http://www.w3.org/2000/svg" data-name="Layer 1" viewBox="0 0 300 300">
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<path class="cls-11" d="M210.5,115.12H171.74V97.82c0-8.14,5.39-10,9.19-10h27.14V52l-39.32-.12c-35.66,0-42.42,26.68-42.42,43.77v19.48H99.09v36.32h27.24v109h45.41v-109h35Z">
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<a class="footer-icon" id="footer_linkedin" href="https://www.linkedin.com/company/ncbinlm" aria-label="LinkedIn"><svg xmlns="http://www.w3.org/2000/svg" data-name="Layer 1" viewBox="0 0 300 300">
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<path class="cls-11" d="M101.64,243.37H57.79v-114h43.85Zm-22-131.54h-.26c-13.25,0-21.82-10.36-21.82-21.76,0-11.65,8.84-21.15,22.33-21.15S101.7,78.72,102,90.38C102,101.77,93.4,111.83,79.63,111.83Zm100.93,52.61A17.54,17.54,0,0,0,163,182v61.39H119.18s.51-105.23,0-114H163v13a54.33,54.33,0,0,1,34.54-12.66c26,0,44.39,18.8,44.39,55.29v58.35H198.1V182A17.54,17.54,0,0,0,180.56,164.44Z">
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<a class="footer-icon" id="footer_github" href="https://github.com/ncbi" aria-label="GitHub"><svg xmlns="http://www.w3.org/2000/svg" data-name="Layer 1" viewBox="0 0 300 300">
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