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2526 lines
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203 KiB
XML
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<h1 class="res_name"><a href="/gene/">Gene</a></h1>
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<h2 class="res_tagline">Genes and mapped phenotypes</h2>
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<div class="search"><div class="search_form"><label for="database" class="offscreen_noflow">Search database</label><select id="database"><optgroup label="Recent"><option value="pubmed">PubMed</option><option value="clinvar">ClinVar</option><option value="medgen">MedGen</option><option value="books" class="last">Books</option></optgroup><optgroup label="All"><option value="gquery">All Databases</option><option value="assembly" data-ac_dict="assembly">Assembly</option><option value="biocollections">Biocollections</option><option value="bioproject">BioProject</option><option value="biosample">BioSample</option><option value="books">Books</option><option value="clinvar">ClinVar</option><option value="cdd">Conserved Domains</option><option value="gap">dbGaP</option><option value="dbvar">dbVar</option><option value="gene" selected="selected" data-ac_dict="gene">Gene</option><option value="genome" data-ac_dict="genome">Genome</option><option value="gds">GEO DataSets</option><option value="geoprofiles">GEO Profiles</option><option value="gtr">GTR</option><option value="ipg">Identical Protein Groups</option><option value="medgen">MedGen</option><option value="mesh">MeSH</option><option value="nlmcatalog">NLM Catalog</option><option value="nuccore" data-ac_dict="nuccore">Nucleotide</option><option value="omim">OMIM</option><option value="pmc">PMC</option><option value="protein" data-ac_dict="protein">Protein</option><option value="proteinclusters">Protein Clusters</option><option value="protfam">Protein Family Models</option><option value="pcassay">PubChem BioAssay</option><option value="pccompound">PubChem Compound</option><option value="pcsubstance">PubChem Substance</option><option value="pubmed">PubMed</option><option value="snp">SNP</option><option value="sra">SRA</option><option value="structure">Structure</option><option value="taxonomy">Taxonomy</option><option value="toolkit">ToolKit</option><option value="toolkitall">ToolKitAll</option><option value="toolkitbookgh">ToolKitBookgh</option></optgroup></select><div class="nowrap"><label for="term" class="offscreen_noflow" accesskey="/">Search term</label><div class="nowrap"><input type="text" name="term" id="term" title="Search Gene. Use up and down arrows to choose an item from the autocomplete." value="" class="jig-ncbiclearbutton jig-ncbiautocomplete" data-jigconfig="dictionary:'gene',disableUrl:'NcbiSearchBarAutoComplCtrl'" autocomplete="off" data-sbconfig="ds:'no',pjs:'yes',afs:'yes'" /></div><button id="search" type="submit" class="button_search nowrap" cmd="go">Search</button></div></div><ul class="searchlinks inline_list"><set></set><li><a href="/gene/advanced">Advanced</a></li><li class="help"><a id="help" class="jig-ncbihelpwindow" target="ncbihelp" name="help" href="/books/NBK3841/">Help</a></li></ul></div>
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<input name="EntrezSystem2.PEntrez.Gene.Gene_PageController.PreviousPageName" sid="1" type="hidden" value="results" />
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<div id="faceted_search" class="facet_hide">
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<h2 class="offscreen_noflow">Result Filters</h2>
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<div class="facet_cont" data-db="gene" data-default_grps="fg_gene-sources,fg_categories,fg_sequence-content,fg_status" data-sd="db:'gene',op:'select',term:'',qk:'5724',linkname:'',idsfromresult:'26273',extra:''"><ul class="facet" data-filter_id="gene-sources" id="_gene-sources"><li class="filter_grp "><div class="clearfix"><h3>Gene sources</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="genomic">Genomic</a></li></ul></li></ul><ul class="facet" data-filter_id="categories" id="_categories"><li class="filter_grp "><div class="clearfix"><h3>Categories</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="alt-splicing">Alternatively spliced</a></li><li class="fil_val"><a href="#" data-value_id="annotated-genes">Annotated genes</a></li><li class="fil_val"><a href="#" data-value_id="gene-type-protein-coding">Protein-coding</a></li></ul></li></ul><ul class="facet" data-filter_id="sequence-content" id="_sequence-content"><li class="filter_grp "><div class="clearfix"><h3>Sequence content</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="seq-ccds">CCDS</a></li><li class="fil_val"><a href="#" data-value_id="seq-ensembl">Ensembl</a></li><li class="fil_val"><a href="#" data-value_id="refseq">RefSeq</a></li></ul></li></ul><ul class="facet" data-filter_id="status" id="_status"><li class="filter_grp "><div class="clearfix"><h3>Status</h3><a href="#" data-value_id="" class="clear clear_show">Clear</a></div><ul><li class="fil_val selected"><a href="#" data-value_id="current-only">Current</a><span class="fcount">(1)</span></li></ul></li></ul><div id="chr-location-facet-wrapper" data-bid="MCID_67c9f39969195c35ad72b66f" data-hid="MCID_67c90f2d64f30b25346ccae2" data-qky="5724" class="disabled" style="display:none"><ul class="facet" data-filter_id="chromosomal-region" id="_chromosomal-region" data-of="yes"><li class="filter_grp of_grp"><div class="clearfix"><h3>Chromosome locations</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><a id="facet_ofchromosomal-region" href="#facet_of_divchromosomal-region" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'middle left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '375px'" data-value_id="fetch_more">more...</a><div id="facet_of_divchromosomal-region" style="display:none;" class="of_popup"><h4>Chromosome locations</h4><label for="organism-filter" style="width:100%;margin-bottom:.2em;" class="">Select an organism by typing or scrolling</label><input type="text" placeholder="Enter text to narrow down the list" id="organism-filter" style="width:98%;" autocomplete="off" /><br /><div id="chr-region-tax-list"><select id="of_chromosomal-region" size="9" class="chr-region-tax-list" style="width:100%;"></select></div><div id="chr-location-info-ctrl" data-disabled="disabled"><div class="chr-field"><label for="chr-name">Chromosome</label><br /><select id="chr-name" class="chr-field" disabled="disabled"></select></div><div class="chr-field"><label for="chr-from">From</label><br /><input type="text" name="chr-from" id="chr-from" disabled="disabled" class="chr-field" /></div><div class="chr-field"><label for="chr-to">To</label><br /><input type="text" name="chr-to" id="chr-to" disabled="disabled" class="chr-field" /></div></div><div class="actions clearfix"><button class="jig-ncbibutton of_add apply-chr" data-jigconfig="'color': 'ui-ncbibutton-blue'">Apply</button></div></div></ul></li></ul></div><ul class="facet facet_reset"><li><a href="#" data-value_id="reset">Clear all</a></li></ul><ul class="facet_tools"><li><a id="more_filter_groups_link" href="#more_filter_groups" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'top left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '180px'">
|
||
Show additional filters</a></li><div id="more_filter_groups" style="display:none;" class="facets_dialog"><button class="ui-ncbipopper-close-button ui-ncbipopper-close-button-generated ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-blue" generated="true" role="button" aria-disabled="false"><span class="ui-button-text">x</span></button><h4>Additional filters</h4><ul class="filter_groups_more facet"><li><input type="checkbox" id="fg_gene-sources" /><label for="fg_gene-sources">Gene sources</label></li><li><input type="checkbox" id="fg_categories" /><label for="fg_categories">Categories</label></li><li><input type="checkbox" id="fg_sequence-content" /><label for="fg_sequence-content">Sequence content</label></li><li><input type="checkbox" id="fg_status" /><label for="fg_status">Status</label></li><li><input type="checkbox" id="fg_chromosomal-region" /><label for="fg_chromosomal-region">Chromosome locations</label></li><li><input id="fg_field_search" type="checkbox" /><label for="fg_field_search">Search fields</label></li></ul><div class="actions clearfix"><button class="filter_groups_more_apply jig-ncbibutton primary-action" id="filter_groups_apply" data-jigconfig="'color': 'ui-ncbibutton-blue'">Show</button></div></div></ul><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetsUrlFrag" sid="1" type="hidden" value="filters=current-only" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetSubmitted" sid="1" type="hidden" value="false" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.BMFacets" sid="1" type="hidden" value="" /></div>
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<span style="display: block; text-align: center;">S</span>
|
||
<span style="display: block; text-align: center;">I</span>
|
||
<span style="display: block; text-align: center;">D</span>
|
||
<span style="display: block; text-align: center;">E</span>
|
||
<span style="display: block; text-align: center;">B</span>
|
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<span style="display: block; text-align: center;">A</span>
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<span style="display: block; text-align: center;">R</span>
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<div class="results_settings one_setting"><ul class="inline_list left display_settings"><li><a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Display" sid="0" href="#" class="jig-ncbipopper" data-jigconfig="triggerPosition : 'bottom center',destPosition : 'top center',destSelector : '#display_settings_menu_report', hasArrow : false,openEvent : 'click',closeEvent : 'click',isTriggerElementCloseClick: false,addCloseButton : false, groupName: 'entrez_pg'" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Display">Full Report<span href="#" class="tgt_dark"></span></a></li></ul><div id="display_settings_menu_report" class="disp_settings tabPopper"><fieldset class="format"><legend>Format</legend><ul class="column_list"><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="1" value="full_report" format="" id="full_report" checked="true" /><label for="full_report">Full Report</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="2" value="full_report" format="text" id="full_reporttext" /><label for="full_reporttext">Full Report (text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="3" value="expression" format="" id="expression" /><label for="expression">Expression</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="4" value="gene_table" format="" id="gene_table" /><label for="gene_table">Gene Table</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="5" value="gene_table" format="text" id="gene_tabletext" /><label for="gene_tabletext">Gene Table (text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="6" value="generif" format="" id="generif" /><label for="generif">GeneRIF</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="7" value="docsum" format="" id="docsum" /><label for="docsum">Summary</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="8" value="docsum" format="text" id="docsumtext" /><label for="docsumtext">Summary (text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="9" value="tabular" format="" id="tabular" /><label for="tabular">Tabular</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="10" value="tabular" format="text" id="tabulartext" /><label for="tabulartext">Tabular (text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="11" value="asn1" format="text" id="asn1text" /><label for="asn1text">ASN.1</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="12" value="xml" format="text" id="xmltext" /><label for="xmltext">XML</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="13" value="uilist" format="text" id="uilisttext" /><label for="uilisttext">UI List</label></li></ul></fieldset></div><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SetDisplay" sid="1" class="button_apply ncbipopper-close-button" style="display:none">Apply</button><h4 class="content_header send_to align_right jig-ncbipopper" id="sendto" data-jigconfig="triggerPosition:'bottom center', destPosition : 'top center',destSelector : '#send_to_menu', hasArrow : false, openEvent : 'click',closeEvent : 'click', isTriggerElementCloseClick: false, addCloseButton:true, groupName: 'entrez_pg', adjustFit:'none'"><a href="#" sourceContent="send_to_menu" class="tgt_dark">Send to:</a><script type="text/javascript">
|
||
jQuery(document).ready( function () {
|
||
jQuery("#send_to_menu input[type='radio']").click( function () {
|
||
var selectedValue = jQuery(this).val().toLowerCase();
|
||
var selectedDiv = jQuery("#send_to_menu div." + selectedValue);
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||
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||
if(selectedDiv.is(":hidden")){
|
||
jQuery("#send_to_menu div.submenu:visible").slideUp();
|
||
selectedDiv.slideDown();
|
||
}
|
||
});
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|
||
});
|
||
|
||
jQuery("#sendto").bind("ncbipopperclose", function(){
|
||
jQuery("#send_to_menu div.submenu:visible").css("display","none");
|
||
jQuery("#send_to_menu input[type='radio']:checked").attr("checked",false);
|
||
});
|
||
|
||
</script></h4><div id="send_to_menu" class="tabPopper send_to"><fieldset><legend>Choose Destination</legend><ul class="column_list"><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="1" value="File" id="dest_File" /><label for="dest_File">File</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="2" value="AddToClipboard" id="dest_AddToClipboard" /><label for="dest_AddToClipboard">Clipboard</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="3" value="AddToCollections" id="dest_AddToCollections" /><label for="dest_AddToCollections">Collections</label></li></ul></fieldset><div class="submenu file" id="submenu_File" style="display: none;"><p id="submenu_File_hint" class="hidden"></p><ul><li><label for="file_format">Format</label><select id="file_format" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FFormat" sid="1"><option value="full_report" format="text" selected="selected">Full Report (text)</option><option value="gene_table" format="text">Gene Table (text)</option><option value="docsum" format="text">Summary (text)</option><option value="tabular" format="text">Tabular (text)</option><option value="asn1" format="text">ASN.1</option><option value="xml" format="text">XML</option><option value="uilist" format="text">UI List</option></select></li></ul><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="1" class="button_apply file ncbipopper-close-button" type="submit" cmd="File">Create File</button></div><div class="submenu addtoclipboard" id="submenu_AddToClipboard" style="display: none;"><p id="submenu_AddToClipboard_hint" class="hidden"></p><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="2" class="button_apply clipboard ncbipopper-close-button" type="submit" cmd="AddToClipboard">Add to Clipboard</button></div><div class="submenu addtocollections" id="submenu_AddToCollections" style="display: none;"><p id="submenu_AddToCollections_hint" class="hidden"></p><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="3" class="button_apply collections ncbipopper-close-button" type="submit" cmd="AddToCollections">Add to Collections</button></div></div><div><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FileFormat" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastPresentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Presentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastPageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Sort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastSort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FileSort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Format" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastFormat" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevPageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevPresentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevSort" sid="1" type="hidden" value="" /><input type="hidden" id="coll_startindex" name="CollectionStartIndex" value="1" /></div></div>
|
||
<div>
|
||
|
||
|
||
|
||
</div>
|
||
<div class="">
|
||
<div><span id="result_sel" class="nowrap"></span><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_ResultsController.ResultCount" sid="1" type="hidden" id="resultcount" value="1" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_ResultsController.RunLastQuery" sid="1" type="hidden" /></div>
|
||
|
||
</div>
|
||
<div id="messagearea" class="empty">
|
||
|
||
|
||
|
||
|
||
</div>
|
||
<div class="rprt full-rprt">
|
||
<div>
|
||
<div class="rprt-header">
|
||
<input type="hidden" id="gene-tax-id" value="9606" />
|
||
<h1 class="title" id="gene-name"><span class="gn" style="padding-right:.5em;">FBXO3</span> F-box protein 3 [ <em class="tax">Homo sapiens</em> (human)
|
||
]
|
||
</h1>
|
||
<span class="geneid">Gene ID: 26273, updated on
|
||
4-Mar-2025</span>
|
||
</div>
|
||
<div class="download-datasets">
|
||
<script type="text/javascript" src="https://cdnjs.cloudflare.com/ajax/libs/axios/0.23.0/axios.min.js"></script>
|
||
<h4 class="download-datasets-popper jig-ncbipopper" id="download-asm" style="align-self:start" data-jigconfig="triggerPosition:'bottom center', destPosition : 'top center',destSelector : '#download-datasets-popper-menu', hasArrow : false, openEvent : 'click',closeEvent : 'click', isTriggerElementCloseClick: false, groupName: 'entrez_pg', adjustFit:'none'" role="button" aria-expanded="false" aria-haspopup="true">
|
||
<svg alt="download" class="dlbtn-icon" x="0px" y="0px" width="15px" height="15px" viewBox="0 0 60 60" enable-background="new 0 0 60 60" xml:space="preserve">
|
||
<g>
|
||
<polygon points="48.75,36.25 48.75,48.75 11.25,48.75 11.25,36.25 5,36.25 5,55 55,55 55,36.25 "></polygon>
|
||
<polygon points="42.5,23.75 36.25,23.75 36.25,5 23.75,5 23.75,23.75 17.5,23.75 30,42.5 "></polygon>
|
||
</g>
|
||
</svg>
|
||
<a href="#">Download Datasets</a>
|
||
</h4>
|
||
<div id="download-datasets-popper-menu" style="display:none;">
|
||
<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-gene-seq-fasta" value="FASTA_GENE" checked="checked" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-gene-seq-fasta">Gene Sequences (FASTA)</label>
|
||
</div>
|
||
<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-transcript-seq-fasta" value="FASTA_RNA" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-transcript-seq-fasta">Transcript sequences (FASTA)</label>
|
||
</div>
|
||
<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-protein-seq-fasta" value="FASTA_PROTEIN" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-protein-seq-fasta">Protein sequences(FASTA)</label>
|
||
</div>
|
||
<p style="margin-left:5px;">In addition, your package will include a detailed data report in both TSV and JSONL formats.</p>
|
||
<div class="input-group">
|
||
<label for="datasets-download-file-name">File name</label>
|
||
<input type="text" id="datasets-download-file-name" placeholder="Name your file" style="padding:5px;" value="FBXO3_datasets.zip" />
|
||
</div>
|
||
<input type="hidden" id="download-datasets-base-url" value="https://api.ncbi.nlm.nih.gov/datasets/v2alpha/gene/download" />
|
||
<input type="hidden" id="gene-id-value" value="26273" />
|
||
<button id="datasets-download-submit" data-ga-action="click_begin_download" data-ga-label="download" class="jig-ncbibutton ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-gray" role="button">
|
||
<span class="ui-button-text">Download</span>
|
||
</button>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-body">
|
||
|
||
|
||
<div class="rprt-section gene-summary">
|
||
<section class="rprt-section-header" id="summary">
|
||
<h2 id="header-summary">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-summary .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Summary</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Summary_2" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div id="summaryDiv" class="section">
|
||
<dl id="summaryDl">
|
||
<dt class="noline"> Official
|
||
Symbol</dt>
|
||
<dd class="noline">FBXO3<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
|
||
<dt> Official
|
||
Full Name</dt>
|
||
<dd>F-box protein 3<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
|
||
<dt>Primary source</dt>
|
||
<dd>
|
||
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:13582" data-gblink-text="Ensembl">HGNC:HGNC:13582</a>
|
||
</dd>
|
||
<dt>See related</dt>
|
||
<dd>
|
||
<a href="http://www.ensembl.org/id/ENSG00000110429" data-gblink-text="Ensembl" class="genome-browser-link" data-genome-browser-link-sort="5" data-gb-url="http://www.ensembl.org/loc/ENSG00000110429">Ensembl:ENSG00000110429</a>
|
||
<a href="https://www.ncbi.nlm.nih.gov/omim/609089" data-gblink-text="Ensembl" ref="ordinalpos=1&ncbi_uid=26273&link_uid=609089">MIM:609089;</a>
|
||
<a href="https://www.alliancegenome.org/gene/HGNC:13582" data-gblink-text="Ensembl" ref="ordinalpos=1&ncbi_uid=26273&link_uid=HGNC:13582">AllianceGenome:HGNC:13582</a>
|
||
</dd>
|
||
<dt>Gene type</dt>
|
||
<dd>protein coding</dd>
|
||
<dt>RefSeq status</dt>
|
||
<dd>REVIEWED</dd>
|
||
<dt>Organism</dt>
|
||
<dd class="tax">
|
||
<a href="/Taxonomy/Browser/wwwtax.cgi?id=9606" ref="ordinalpos=1&ncbi_uid=26273&link_uid=9606">Homo sapiens</a>
|
||
</dd>
|
||
<dt>Lineage</dt>
|
||
<dd class="tax">Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo</dd>
|
||
<dt>Also known as</dt>
|
||
<dd>FBA; FBX3</dd>
|
||
<dt>Summary</dt>
|
||
<dd>This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants diverging at the 3' end. [provided by RefSeq, Jul 2008]</dd>
|
||
<dt>Expression</dt>
|
||
<dd>Ubiquitous expression in thyroid (RPKM 11.3), kidney (RPKM 10.4) and 25 other tissues <a href="#gene-expression">See more</a></dd>
|
||
<dt>Orthologs</dt>
|
||
<dd class="ortholog-links">
|
||
<a href="https://www.ncbi.nlm.nih.gov/gene/57443">mouse</a>
|
||
<a href="/gene/26273/ortholog/">all</a>
|
||
</dd>
|
||
<dt style="padding-top:.5em;">
|
||
<span class="new-icon">NEW</span>
|
||
</dt>
|
||
<dd style="padding-top:.5em;">
|
||
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/26273/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="gene_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Gene table</a></strong>
|
||
<br />
|
||
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/26273/products/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="transcript_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Transcript table</a></strong>
|
||
</dd>
|
||
</dl>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-genomic-context">
|
||
<section class="rprt-section-header" id="genomic-context">
|
||
<h2 id="header-genomic-context">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-context .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Genomic context</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Genomic_Context" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div class="gc_cont">
|
||
<div class="gt_cont_contents">
|
||
<div style="float:right"><span>See FBXO3 in </span><a href="/genome/gdv/?context=gene&acc=26273" class="link-to-gdv genome-browser-link" data-genome-browser-link-sort="1" data-acc="GCF_000001405.40">Genome Data Viewer</a> </div>
|
||
<dl class="dl-chr-info" style="float:left;margin-top:0;">
|
||
<dt>Location: </dt>
|
||
<dd>
|
||
<span style="display:inline-block;">11p13</span>
|
||
</dd>
|
||
</dl>
|
||
</div>
|
||
<dl class="dl-chr-info exon-count">
|
||
<dt>Exon count: </dt>
|
||
<dd>11</dd>
|
||
</dl>
|
||
<div class="ui-ncbigrid-outer-div" id="genomic-context-tbl-location">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="">
|
||
<thead>
|
||
<tr>
|
||
<th style="max-width:15%">Annotation release</th>
|
||
<th style="max-width:10%">Status</th>
|
||
<th>Assembly</th>
|
||
<th>
|
||
<span title="Chromosome">Chr</span>
|
||
</th>
|
||
<th>Location</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td>RS_2024_08</td>
|
||
<td>current</td>
|
||
<td>GRCh38.p14 (<a href="/assembly/GCF_000001405.40/" ref="ncbi_uid=26273&link_uid=GCF_000001405.40">GCF_000001405.40</a>)</td>
|
||
<td>11</td>
|
||
<td>NC_000011.10 (33740944..33774520, complement) </td>
|
||
</tr>
|
||
<tr>
|
||
<td>RS_2024_08</td>
|
||
<td>current</td>
|
||
<td>T2T-CHM13v2.0 (<a href="/assembly/GCF_009914755.1/" ref="ncbi_uid=26273&link_uid=GCF_009914755.1">GCF_009914755.1</a>)</td>
|
||
<td>11</td>
|
||
<td>NC_060935.1 (33877954..33911529, complement) </td>
|
||
</tr>
|
||
<tr>
|
||
<td>RS_2024_09</td>
|
||
<td>previous assembly</td>
|
||
<td>GRCh37.p13 (<a href="/assembly/GCF_000001405.25/" ref="ncbi_uid=26273&link_uid=GCF_000001405.25">GCF_000001405.25</a>)</td>
|
||
<td>11</td>
|
||
<td>NC_000011.9 (33762490..33796066, complement) </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<p class="withnote margin_t2em"><strong>Chromosome 11 - NC_000011.10</strong><img usemap="#nbrMap26273_568815587" border="0" alt="Genomic Context describing neighboring genes" src="/gutils/geneneighb.fcgi?geneid=26273&nuc_gi=568815587&n0=KIAA1549L&n1=LOC105376617&n2=LOC126861178&n3=LOC130005511&n4=LOC126861179&n5=C11orf91&n6=LOC130005512&n7=LOC130005513&n8=CD59&n9=LOC130005514&n10=LOC130005515&n11=LOC130005516&n12=FBXO3&n13=LOC130005517&n14=LOC124421514&n15=LOC127820721&n16=LOC130005518&n17=FBXO3-DT&n18=SPICP1" /><map name="nbrMap26273_568815587" id="nbrMap26273_568815587">
|
||
<area shape="rect" onMouseOver="showtip(this,event,'KIAA1549 like')" onMouseOut="hidetip()" coords="17,23,324,31" alt="Neighboring gene KIAA1549 like" href="/gene/25758" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC105376617')" onMouseOut="hidetip()" coords="244,35,321,43" alt="Neighboring gene uncharacterized LOC105376617" href="/gene/105376617" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'MED14-independent group 3 enhancer GRCh37_chr11:33676703-33677902')" onMouseOut="hidetip()" coords="245,47,315,55" alt="Neighboring gene MED14-independent group 3 enhancer GRCh37_chr11:33676703-33677902" href="/gene/126861178" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 4582')" onMouseOut="hidetip()" coords="246,59,316,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4582" href="/gene/130005511" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:33711673-33712872')" onMouseOut="hidetip()" coords="276,71,346,79" alt="Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr11:33711673-33712872" href="/gene/126861179" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 3239')" onMouseOut="hidetip()" coords="285,83,355,91" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3239" href="/gene/130005512" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 3240')" onMouseOut="hidetip()" coords="285,95,355,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3240" href="/gene/130005513" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'chromosome 11 open reading frame 91')" onMouseOut="hidetip()" coords="303,107,353,115" alt="Neighboring gene chromosome 11 open reading frame 91" href="/gene/100131378" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 4583')" onMouseOut="hidetip()" coords="305,119,375,127" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4583" href="/gene/130005514" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 4584')" onMouseOut="hidetip()" coords="313,131,383,139" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4584" href="/gene/130005515" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 3241')" onMouseOut="hidetip()" coords="316,47,386,55" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3241" href="/gene/130005516" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'CD59 molecule (CD59 blood group)')" onMouseOut="hidetip()" coords="327,23,378,31" alt="Neighboring gene CD59 molecule (CD59 blood group)" href="/gene/966" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 4585')" onMouseOut="hidetip()" coords="338,35,408,43" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4585" href="/gene/130005517" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 12829')" onMouseOut="hidetip()" coords="347,59,417,67" alt="Neighboring gene Sharpr-MPRA regulatory region 12829" href="/gene/124421514" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr11:33795080-33795580')" onMouseOut="hidetip()" coords="348,71,418,79" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:33795080-33795580" href="/gene/127820721" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 3243')" onMouseOut="hidetip()" coords="349,143,419,151" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 3243" href="/gene/130005518" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'FBXO3 divergent transcript')" onMouseOut="hidetip()" coords="369,83,419,91" alt="Neighboring gene FBXO3 divergent transcript" href="/gene/101928440" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'Spi-C transcription factor pseudogene 1')" onMouseOut="hidetip()" coords="383,23,423,31" alt="Neighboring gene Spi-C transcription factor pseudogene 1" href="/gene/646120" />
|
||
</map>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-genomic-regions-transcripts-products">
|
||
<section class="rprt-section-header" id="genomic-regions-transcripts-products">
|
||
<h2 id="header-genomic-regions-transcripts-products">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-regions-transcripts-products .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Genomic regions, transcripts, and products</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Genomic_Regions_Transcripts_a" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<div style="text-align:right;">Go to <a href="#reference-sequences">reference sequence details</a></div>
|
||
</div>
|
||
<div>
|
||
<p class="choose">
|
||
<label for="accession" class="label">Genomic Sequence: </label>
|
||
<select name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.accessionList" sid="1" id="accessionList" data-taxid="9606" data-geneid="26273">
|
||
<option value="NC_000011.10_33740943_33774519">NC_000011.10 Chromosome 11 Reference GRCh38.p14 Primary Assembly</option>
|
||
<option value="NC_060935.1_33877953_33911528">NC_060935.1 Chromosome 11 Alternate T2T-CHM13v2.0</option>
|
||
<option value="NC_000011.9_33762489_33796065">NC_000011.9 Chromosome 11 Reference GRCh37.p13 Primary Assembly</option>
|
||
</select>
|
||
</p>
|
||
</div>
|
||
<div id="NC_000011" class="divAccession">
|
||
<div class="seq-viewer">
|
||
<p class="note-link">
|
||
<strong>Go to nucleotide:</strong>
|
||
<a title="Nucleotide Graphic report" href="/nuccore/NC_000011.10?report=graph&from=33735907&to=33779555&strand=true&app_context=Gene&assm_context=GCF_000001405.40" ref="ordinalpos=1&ncbi_uid=26273&link_uid=NC_000011.10">Graphics</a>
|
||
<a title="Nucleotide FASTA report" href="/nuccore/NC_000011.10?report=fasta&from=33740944&to=33774520&strand=true" ref="ordinalpos=1&ncbi_uid=26273&link_uid=NC_000011.10">FASTA</a>
|
||
<a title="Nucleotide GenBank report" href="/nuccore/NC_000011.10?report=genbank&from=33740944&to=33774520&strand=true" ref="ordinalpos=1&ncbi_uid=26273&link_uid=NC_000011.10">GenBank</a>
|
||
</p>
|
||
<div id="divNC_000011" class="SeqViewerApp" style="clear:both;" data-sv="appname=ncbigene&embedded=true&noslider=1&id=NC_000011.10&from=33735907&to=33779555&strand=true&app_context=Gene&assm_context=GCF_000001405.40">
|
||
<a href="?appname=ncbigene&embedded=true&noslider=1&id=NC_000011.10&from=33735907&to=33779555&strand=true&app_context=Gene&assm_context=GCF_000001405.40"></a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000011.10" sid="1" type="hidden" id="nucleotideLink_NC_000011_10_33740943_33774519" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_000011.10?report=graph&amp;from=33735907&amp;to=33779555&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" ref="ordinalpos=1&amp;ncbi_uid=26273&amp;link_uid=NC_000011.10">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_000011.10?report=fasta&amp;from=33740944&amp;to=33774520&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=26273&amp;link_uid=NC_000011.10">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_000011.10?report=genbank&amp;from=33740944&amp;to=33774520&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=26273&amp;link_uid=NC_000011.10">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000011.10" sid="1" type="hidden" id="relString_NC_000011_10_33740943_33774519" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000011.10&amp;from=33735907&amp;to=33779555&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_060935.1" sid="1" type="hidden" id="nucleotideLink_NC_060935_1_33877953_33911528" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_060935.1?report=graph&amp;from=33872917&amp;to=33916564&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_009914755.1" ref="ordinalpos=1&amp;ncbi_uid=26273&amp;link_uid=NC_060935.1">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_060935.1?report=fasta&amp;from=33877954&amp;to=33911529&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=26273&amp;link_uid=NC_060935.1">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_060935.1?report=genbank&amp;from=33877954&amp;to=33911529&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=26273&amp;link_uid=NC_060935.1">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_060935.1" sid="1" type="hidden" id="relString_NC_060935_1_33877953_33911528" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_060935.1&amp;from=33872917&amp;to=33916564&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_009914755.1" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000011.9" sid="1" type="hidden" id="nucleotideLink_NC_000011_9_33762489_33796065" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_000011.9?report=graph&amp;from=33757453&amp;to=33801101&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.25" ref="ordinalpos=1&amp;ncbi_uid=26273&amp;link_uid=NC_000011.9">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_000011.9?report=fasta&amp;from=33762490&amp;to=33796066&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=26273&amp;link_uid=NC_000011.9">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_000011.9?report=genbank&amp;from=33762490&amp;to=33796066&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=26273&amp;link_uid=NC_000011.9">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000011.9" sid="1" type="hidden" id="relString_NC_000011_9_33762489_33796065" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000011.9&amp;from=33757453&amp;to=33801101&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.25" />
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-gene-expression">
|
||
<section class="rprt-section-header" id="gene-expression">
|
||
<h2 id="header-gene-expression">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-gene-expression .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Expression</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Expression" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<div style="text-align:right;">
|
||
<a href="/gene/26273/?report=expression" data-url="/gene/26273/?report=expression" id="gene-expression-see-details">See details</a>
|
||
</div>
|
||
<div id="gene-expression-app" data-url="https://www.ncbi.nlm.nih.gov/gene/26273" data-report-type="summary">
|
||
<div>
|
||
<script type="text/javascript">
|
||
|
||
window.tissues_data = {'adrenal 10wk': {'id': '26273_Adrenal_10wk_PRJNA270632', 'gene': 26273, 'source_name': 'adrenal 10wk', 'full_rpkm': 3.45817, 'exp_rpkm': 3.46, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269960}, 'adrenal 16wk': {'id': '26273_Adrenal_16wk_PRJNA270632', 'gene': 26273, 'source_name': 'adrenal 16wk', 'full_rpkm': 3.3333, 'exp_rpkm': 3.33, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269961}, 'adrenal 18wk': {'id': '26273_Adrenal_18wk_PRJNA270632', 'gene': 26273, 'source_name': 'adrenal 18wk', 'full_rpkm': 3.9634, 'exp_rpkm': 3.96, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269962}, 'adrenal 20wk': {'id': '26273_Adrenal_20wk_PRJNA270632', 'gene': 26273, 'source_name': 'adrenal 20wk', 'full_rpkm': 3.93233, 'exp_rpkm': 3.93, 'var': 0.0825772, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269963}, 'heart 10wk': {'id': '26273_Heart_10wk;_PRJNA270632', 'gene': 26273, 'source_name': 'heart 10wk', 'full_rpkm': 3.37111, 'exp_rpkm': 3.37, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269964}, 'heart 11wk': {'id': '26273_Heart_11wk;_PRJNA270632', 'gene': 26273, 'source_name': 'heart 11wk', 'full_rpkm': 3.83787, 'exp_rpkm': 3.84, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269965}, 'heart 17wk': {'id': '26273_Heart_17wk;_PRJNA270632', 'gene': 26273, 'source_name': 'heart 17wk', 'full_rpkm': 3.87029, 'exp_rpkm': 3.87, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269966}, 'heart 18wk': {'id': '26273_Heart_18wk;_PRJNA270632', 'gene': 26273, 'source_name': 'heart 18wk', 'full_rpkm': 3.97793, 'exp_rpkm': 3.98, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269967}, 'heart 20wk': {'id': '26273_Heart_20wk_PRJNA270632', 'gene': 26273, 'source_name': 'heart 20wk', 'full_rpkm': 5.18111, 'exp_rpkm': 5.18, 'var': 1.046283, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269968}, 'intestine 10wk': {'id': '26273_Intestine_10wk_PRJNA270632', 'gene': 26273, 'source_name': 'intestine 10wk', 'full_rpkm': 3.85455, 'exp_rpkm': 3.85, 'var': 2.34584, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269969}, 'intestine 11wk': {'id': '26273_Intestine_11wk_PRJNA270632', 'gene': 26273, 'source_name': 'intestine 11wk', 'full_rpkm': 4.96864, 'exp_rpkm': 4.97, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269970}, 'intestine 15wk': {'id': '26273_Intestine_15wk_PRJNA270632', 'gene': 26273, 'source_name': 'intestine 15wk', 'full_rpkm': 2.92662, 'exp_rpkm': 2.93, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269971}, 'intestine 17wk': {'id': '26273_Intestine_17wk_PRJNA270632', 'gene': 26273, 'source_name': 'intestine 17wk', 'full_rpkm': 1.51523, 'exp_rpkm': 1.52, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269972}, 'intestine 20wk': {'id': '26273_Intestine_20wk_PRJNA270632', 'gene': 26273, 'source_name': 'intestine 20wk', 'full_rpkm': 4.85515, 'exp_rpkm': 4.86, 'var': 0.0395472, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269973}, 'kidney 10wk': {'id': '26273_Kidney_10wk_PRJNA270632', 'gene': 26273, 'source_name': 'kidney 10wk', 'full_rpkm': 3.08083, 'exp_rpkm': 3.08, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269974}, 'kidney 16wk': {'id': '26273_Kidney_16wk_PRJNA270632', 'gene': 26273, 'source_name': 'kidney 16wk', 'full_rpkm': 1.97875, 'exp_rpkm': 1.98, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269975}, 'kidney 20wk': {'id': '26273_Kidney_20wk_PRJNA270632', 'gene': 26273, 'source_name': 'kidney 20wk', 'full_rpkm': 1.14557, 'exp_rpkm': 1.15, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269976}, 'lung 10wk': {'id': '26273_Lung_10wk_PRJNA270632', 'gene': 26273, 'source_name': 'lung 10wk', 'full_rpkm': 2.89349, 'exp_rpkm': 2.89, 'var': 0.00031907, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269977}, 'lung 17wk': {'id': '26273_Lung_17wk_PRJNA270632', 'gene': 26273, 'source_name': 'lung 17wk', 'full_rpkm': 4.98997, 'exp_rpkm': 4.99, 'var': 0.0900118, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269978}, 'lung 20wk': {'id': '26273_Lung_20wk_PRJNA270632', 'gene': 26273, 'source_name': 'lung 20wk', 'full_rpkm': 3.70939, 'exp_rpkm': 3.71, 'var': 1.047418, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269979}, 'stomach 10wk': {'id': '26273_Stomach_10wk_PRJNA270632', 'gene': 26273, 'source_name': 'stomach 10wk', 'full_rpkm': 2.14043, 'exp_rpkm': 2.14, 'var': 0.00214168, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269980}, 'stomach 16wk': {'id': '26273_Stomach_16wk_PRJNA270632', 'gene': 26273, 'source_name': 'stomach 16wk', 'full_rpkm': 3.51447, 'exp_rpkm': 3.51, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269981}, 'stomach 18wk': {'id': '26273_Stomach_18wk_PRJNA270632', 'gene': 26273, 'source_name': 'stomach 18wk', 'full_rpkm': 3.80611, 'exp_rpkm': 3.81, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269982}, 'stomach 20wk': {'id': '26273_Stomach_20wk_PRJNA270632', 'gene': 26273, 'source_name': 'stomach 20wk', 'full_rpkm': 4.2116, 'exp_rpkm': 4.21, 'var': 0.2369766, 'project_desc': 'PRJNA270632', '_version_': 1785734421206269983}};
|
||
|
||
|
||
|
||
|
||
window.details_data = {"adrenal 10wk": [{"id": "metadata_9606_SAMN03267754", "gene": 26273, "sample_id": "SAMN03267754", "full_rpkm": 3.45817, "exp_rpkm": 3.46, "exp_total": 88996, "project_desc": "PRJNA270632", "_version_": 1785734387345653765, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 10wk", "exp_Mcount": 4852.92}], "adrenal 16wk": [{"id": "metadata_9606_SAMN03267755", "gene": 26273, "sample_id": "SAMN03267755", "full_rpkm": 3.3333, "exp_rpkm": 3.33, "exp_total": 128496, "project_desc": "PRJNA270632", "_version_": 1785734387345653764, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 16wk", "exp_Mcount": 7269.31}], "adrenal 18wk": [{"id": "metadata_9606_SAMN03267761", "gene": 26273, "sample_id": "SAMN03267761", "full_rpkm": 3.9634, "exp_rpkm": 3.96, "exp_total": 140303, "project_desc": "PRJNA270632", "_version_": 1785734387345653763, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 18wk", "exp_Mcount": 6675.41}], "adrenal 20wk": [{"id": "metadata_9606_SAMN03267762", "gene": 26273, "sample_id": "SAMN03267762", "full_rpkm": 3.64497, "exp_rpkm": 3.64, "exp_total": 146163, "project_desc": "PRJNA270632", "_version_": 1785734387345653761, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 20wk", "exp_Mcount": 7561.75}, {"id": "metadata_9606_SAMN03267753", "gene": 26273, "sample_id": "SAMN03267753", "full_rpkm": 4.21969, "exp_rpkm": 4.22, "exp_total": 148762, "project_desc": "PRJNA270632", "_version_": 1785734387345653762, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 20wk", "exp_Mcount": 6647.98}], "heart 10wk": [{"id": "metadata_9606_SAMN03267750", "gene": 26273, "sample_id": "SAMN03267750", "full_rpkm": 3.37111, "exp_rpkm": 3.37, "exp_total": 95466, "project_desc": "PRJNA270632", "_version_": 1785734387345653760, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 10wk", "exp_Mcount": 5340.16}], "heart 11wk": [{"id": "metadata_9606_SAMN03267763", "gene": 26273, "sample_id": "SAMN03267763", "full_rpkm": 3.83787, "exp_rpkm": 3.84, "exp_total": 120833, "project_desc": "PRJNA270632", "_version_": 1785734387344605210, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 11wk", "exp_Mcount": 5937.09}], "heart 17wk": [{"id": "metadata_9606_SAMN03267757", "gene": 26273, "sample_id": "SAMN03267757", "full_rpkm": 3.87029, "exp_rpkm": 3.87, "exp_total": 162298, "project_desc": "PRJNA270632", "_version_": 1785734387344605209, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 17wk", "exp_Mcount": 7907.66}], "heart 18wk": [{"id": "metadata_9606_SAMN03267751", "gene": 26273, "sample_id": "SAMN03267751", "full_rpkm": 3.97793, "exp_rpkm": 3.98, "exp_total": 134605, "project_desc": "PRJNA270632", "_version_": 1785734387344605208, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 18wk", "exp_Mcount": 6380.91}], "heart 20wk": [{"id": "metadata_9606_SAMN03267756", "gene": 26273, "sample_id": "SAMN03267756", "full_rpkm": 4.74567, "exp_rpkm": 4.75, "exp_total": 273216, "project_desc": "PRJNA270632", "_version_": 1785734387344605205, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 20wk", "exp_Mcount": 10856.4}, {"id": "metadata_9606_SAMN03267764", "gene": 26273, "sample_id": "SAMN03267764", "full_rpkm": 6.5935, "exp_rpkm": 6.59, "exp_total": 178238, "project_desc": "PRJNA270632", "_version_": 1785734387344605206, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 20wk", "exp_Mcount": 5097.56}, {"id": "metadata_9606_SAMN03267760", "gene": 26273, "sample_id": "SAMN03267760", "full_rpkm": 4.20418, "exp_rpkm": 4.2, "exp_total": 133636, "project_desc": "PRJNA270632", "_version_": 1785734387344605207, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 20wk", "exp_Mcount": 5994.06}], "intestine 10wk": [{"id": "metadata_9606_SAMN03267752", "gene": 26273, "sample_id": "SAMN03267752", "full_rpkm": 2.32294, "exp_rpkm": 2.32, "exp_total": 96193, "project_desc": "PRJNA270632", "_version_": 1785734387344605203, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 10wk", "exp_Mcount": 7808.8}, {"id": "metadata_9606_SAMN03267759", "gene": 26273, "sample_id": "SAMN03267759", "full_rpkm": 5.38617, "exp_rpkm": 5.39, "exp_total": 197279, "project_desc": "PRJNA270632", "_version_": 1785734387344605204, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 10wk", "exp_Mcount": 6906.84}], "intestine 11wk": [{"id": "metadata_9606_SAMN03267758", "gene": 26273, "sample_id": "SAMN03267758", "full_rpkm": 4.96864, "exp_rpkm": 4.97, "exp_total": 114219, "project_desc": "PRJNA270632", "_version_": 1785734387344605202, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 11wk", "exp_Mcount": 4334.9}], "intestine 15wk": [{"id": "metadata_9606_SAMN03267775", "gene": 26273, "sample_id": "SAMN03267775", "full_rpkm": 2.92662, "exp_rpkm": 2.93, "exp_total": 61776, "project_desc": "PRJNA270632", "_version_": 1785734387344605201, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 15wk", "exp_Mcount": 3980.45}], "intestine 17wk": [{"id": "metadata_9606_SAMN03267782", "gene": 26273, "sample_id": "SAMN03267782", "full_rpkm": 1.51523, "exp_rpkm": 1.52, "exp_total": 77666, "project_desc": "PRJNA270632", "_version_": 1785734387344605200, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 17wk", "exp_Mcount": 9665.65}], "intestine 20wk": [{"id": "metadata_9606_SAMN03267766", "gene": 26273, "sample_id": "SAMN03267766", "full_rpkm": 4.65629, "exp_rpkm": 4.66, "exp_total": 102751, "project_desc": "PRJNA270632", "_version_": 1785734387344605198, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 20wk", "exp_Mcount": 4161.26}, {"id": "metadata_9606_SAMN03267769", "gene": 26273, "sample_id": "SAMN03267769", "full_rpkm": 5.05402, "exp_rpkm": 5.05, "exp_total": 104365, "project_desc": "PRJNA270632", "_version_": 1785734387344605199, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 20wk", "exp_Mcount": 3894.01}], "kidney 10wk": [{"id": "metadata_9606_SAMN03267784", "gene": 26273, "sample_id": "SAMN03267784", "full_rpkm": 3.08083, "exp_rpkm": 3.08, "exp_total": 77205, "project_desc": "PRJNA270632", "_version_": 1785734387344605197, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "kidney 10wk", "exp_Mcount": 4725.59}], "kidney 16wk": [{"id": "metadata_9606_SAMN03267772", "gene": 26273, "sample_id": "SAMN03267772", "full_rpkm": 1.97875, "exp_rpkm": 1.98, "exp_total": 160424, "project_desc": "PRJNA270632", "_version_": 1785734387344605196, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "kidney 16wk", "exp_Mcount": 15288.2}], "kidney 20wk": [{"id": "metadata_9606_SAMN03267777", "gene": 26273, "sample_id": "SAMN03267777", "full_rpkm": 1.14557, "exp_rpkm": 1.15, "exp_total": 62451, "project_desc": "PRJNA270632", "_version_": 1785734387344605195, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "kidney 20wk", "exp_Mcount": 10280.0}], "lung 10wk": [{"id": "metadata_9606_SAMN03267770", "gene": 26273, "sample_id": "SAMN03267770", "full_rpkm": 2.91136, "exp_rpkm": 2.91, "exp_total": 91904, "project_desc": "PRJNA270632", "_version_": 1785734387344605193, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 10wk", "exp_Mcount": 5952.75}, {"id": "metadata_9606_SAMN03267767", "gene": 26273, "sample_id": "SAMN03267767", "full_rpkm": 2.87563, "exp_rpkm": 2.88, "exp_total": 79774, "project_desc": "PRJNA270632", "_version_": 1785734387344605194, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 10wk", "exp_Mcount": 5231.26}], "lung 17wk": [{"id": "metadata_9606_SAMN03267778", "gene": 26273, "sample_id": "SAMN03267778", "full_rpkm": 4.68996, "exp_rpkm": 4.69, "exp_total": 155548, "project_desc": "PRJNA270632", "_version_": 1785734387344605191, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 17wk", "exp_Mcount": 6254.23}, {"id": "metadata_9606_SAMN03267776", "gene": 26273, "sample_id": "SAMN03267776", "full_rpkm": 5.28999, "exp_rpkm": 5.29, "exp_total": 105011, "project_desc": "PRJNA270632", "_version_": 1785734387344605192, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 17wk", "exp_Mcount": 3743.33}], "lung 20wk": [{"id": "metadata_9606_SAMN03267780", "gene": 26273, "sample_id": "SAMN03267780", "full_rpkm": 2.68595, "exp_rpkm": 2.69, "exp_total": 132040, "project_desc": "PRJNA270632", "_version_": 1785734387344605189, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 20wk", "exp_Mcount": 9270.13}, {"id": "metadata_9606_SAMN03267768", "gene": 26273, "sample_id": "SAMN03267768", "full_rpkm": 4.73282, "exp_rpkm": 4.73, "exp_total": 159437, "project_desc": "PRJNA270632", "_version_": 1785734387344605190, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 20wk", "exp_Mcount": 6352.54}], "stomach 10wk": [{"id": "metadata_9606_SAMN03267773", "gene": 26273, "sample_id": "SAMN03267773", "full_rpkm": 2.18671, "exp_rpkm": 2.19, "exp_total": 76326, "project_desc": "PRJNA270632", "_version_": 1785734387344605187, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 10wk", "exp_Mcount": 6582.02}, {"id": "metadata_9606_SAMN03267779", "gene": 26273, "sample_id": "SAMN03267779", "full_rpkm": 2.09416, "exp_rpkm": 2.09, "exp_total": 80336, "project_desc": "PRJNA270632", "_version_": 1785734387344605188, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 10wk", "exp_Mcount": 7234.02}], "stomach 16wk": [{"id": "metadata_9606_SAMN03267774", "gene": 26273, "sample_id": "SAMN03267774", "full_rpkm": 3.51447, "exp_rpkm": 3.51, "exp_total": 115913, "project_desc": "PRJNA270632", "_version_": 1785734387344605186, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 16wk", "exp_Mcount": 6219.43}], "stomach 18wk": [{"id": "metadata_9606_SAMN03267771", "gene": 26273, "sample_id": "SAMN03267771", "full_rpkm": 3.80611, "exp_rpkm": 3.81, "exp_total": 117478, "project_desc": "PRJNA270632", "_version_": 1785734387344605185, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 18wk", "exp_Mcount": 5820.42}], "stomach 20wk": [{"id": "metadata_9606_SAMN03267765", "gene": 26273, "sample_id": "SAMN03267765", "full_rpkm": 4.89588, "exp_rpkm": 4.9, "exp_total": 116692, "project_desc": "PRJNA270632", "_version_": 1785734387342508032, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4494.58}, {"id": "metadata_9606_SAMN03267781", "gene": 26273, "sample_id": "SAMN03267781", "full_rpkm": 3.93496, "exp_rpkm": 3.93, "exp_total": 95284, "project_desc": "PRJNA270632", "_version_": 1785734387343556608, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4566.24}, {"id": "metadata_9606_SAMN03267783", "gene": 26273, "sample_id": "SAMN03267783", "full_rpkm": 3.80397, "exp_rpkm": 3.8, "exp_total": 96920, "project_desc": "PRJNA270632", "_version_": 1785734387344605184, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4804.58}]}
|
||
window.taxId = 9606
|
||
</script>
|
||
|
||
|
||
<div>
|
||
|
||
|
||
|
||
<select name="p" id="project-selector">
|
||
|
||
|
||
<option value="SRP051249" selected="selected" data-bioproject="PRJNA270632">
|
||
|
||
Tissue-specific circular RNA induction during human fetal development
|
||
|
||
</option>
|
||
|
||
|
||
|
||
<option value="SRP056969" data-bioproject="PRJNA280600">
|
||
|
||
RNA sequencing of total RNA from 20 human tissues
|
||
|
||
|
||
</option>
|
||
|
||
|
||
|
||
<option value="ERP003613" data-bioproject="PRJEB4337">
|
||
|
||
HPA RNA-seq normal tissues
|
||
|
||
|
||
</option>
|
||
|
||
|
||
|
||
</select>
|
||
|
||
|
||
|
||
<ul id="project-summary">
|
||
<li id="project-summary-title">Project title:
|
||
|
||
Tissue-specific circular RNA induction during human fetal development
|
||
|
||
</li>
|
||
|
||
|
||
<li id="project-summary-desc">Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA</li>
|
||
|
||
|
||
|
||
<li id="project-summary-bioprojects">BioProject: <a href="/bioproject/PRJNA270632/">PRJNA270632</a>
|
||
</li>
|
||
|
||
<li id="project-summary-pubs">Publication:
|
||
|
||
|
||
<span><a href="/pubmed/26076956/">PMID 26076956</a></span>
|
||
|
||
</li>
|
||
|
||
|
||
<li id="project-summary-analysis-date">Analysis date: Mon Apr 2 22:54:59 2018</li>
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
<div id="gene-expr-details" class="expression-chart"></div>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<script type="text/javascript" src="https://www.gstatic.com/charts/loader.js"></script>
|
||
<script type="text/javascript">
|
||
google.charts.load('current', {
|
||
'packages':[ 'corechart']
|
||
});
|
||
|
||
</script>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-bibliography">
|
||
<section class="rprt-section-header" id="bibliography"><h2 id="header-bibliography"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-bibliography .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Bibliography</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Bibliography" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
|
||
<div class="rprt-section-body" style="">
|
||
<div class="generif-pubmed">
|
||
<h3 id="relatedarticlesinpubmed">
|
||
<a href="#" class="jig-ncbitoggler-open">Related articles in PubMed</a>
|
||
</h3>
|
||
<div class="generefbl-link">
|
||
<ol class="generef-link">
|
||
<li>
|
||
<a href="/pubmed/30448480/" ref="ordinalpos=1&ncbi_uid=26273&link_uid=30448480">The SCFFBXO3 ubiquitin E3 ligase regulates inflammation in atherosclerosis.</a>
|
||
<span class="pubmed-auth-date"> Chandra D, <em>et al</em>. J Mol Cell Cardiol, 2019 Jan. PMID 30448480, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC7425077/" ref="ordinalpos=0&ncbi_uid=26273&link_uid=PMC7425077">Free PMC Article</a></span></span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/27010866/" ref="ordinalpos=2&ncbi_uid=26273&link_uid=27010866">Crystal structure and interaction studies of the human FBxo3 ApaG domain.</a>
|
||
<span class="pubmed-auth-date"> Krzysiak TC, <em>et al</em>. FEBS J, 2016 Jun. PMID 27010866, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC5065005/" ref="ordinalpos=0&ncbi_uid=26273&link_uid=PMC5065005">Free PMC Article</a></span></span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/30171069/" ref="ordinalpos=3&ncbi_uid=26273&link_uid=30171069">The SCF(FBXO46) ubiquitin ligase complex mediates degradation of the tumor suppressor FBXO31 and thereby prevents premature cellular senescence.</a>
|
||
<span class="pubmed-auth-date"> Choppara S, <em>et al</em>. J Biol Chem, 2018 Oct 19. PMID 30171069, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC6200945/" ref="ordinalpos=0&ncbi_uid=26273&link_uid=PMC6200945">Free PMC Article</a></span></span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/24403578/" ref="ordinalpos=4&ncbi_uid=26273&link_uid=24403578">Virulence factor NSs of rift valley fever virus recruits the F-box protein FBXO3 to degrade subunit p62 of general transcription factor TFIIH.</a>
|
||
<span class="pubmed-auth-date"> Kainulainen M, <em>et al</em>. J Virol, 2014 Mar. PMID 24403578, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC3957945/" ref="ordinalpos=0&ncbi_uid=26273&link_uid=PMC3957945">Free PMC Article</a></span></span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/25721664/" ref="ordinalpos=5&ncbi_uid=26273&link_uid=25721664">F-box protein Fbxo3 targets Smurf1 ubiquitin ligase for ubiquitination and degradation.</a>
|
||
<span class="pubmed-auth-date"> Li D, <em>et al</em>. Biochem Biophys Res Commun, 2015 Mar 20. PMID 25721664</span>
|
||
</li>
|
||
</ol>
|
||
<p class="see-all-pm">
|
||
<a href="/pubmed?LinkName=gene_pubmed&from_uid=26273" title="See all 73 citations in Pubmed">See all (73) citations in PubMed</a>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="generif-pubmed generif">
|
||
<h3 id="generifsgenereferencesintofunctions">
|
||
<a href="#" class="jig-ncbitoggler-open">GeneRIFs: Gene References Into Functions</a>
|
||
</h3>
|
||
<div>
|
||
<a href="/gene/about-generif" class="whatisthis">What's a GeneRIF?</a>
|
||
<div class="generefbl-link">
|
||
<ol class="generef-link">
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/38134227" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=26273&link_uid=38134227">FBXO3 stabilizes USP4 and Twist1 to promote PI3K-mediated breast cancer metastasis.</a>
|
||
<div id="gene-popper1" class="gene-rif-popper">Title: FBXO3 stabilizes USP4 and Twist1 to promote PI3K-mediated breast cancer metastasis.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/30448480" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=26273&link_uid=30448480">FBXO3 potentiates vascular inflammation and atherosclerosis that can be effectively mitigated by a small molecule inhibitor.</a>
|
||
<div id="gene-popper2" class="gene-rif-popper">Title: The SCFFBXO3 ubiquitin E3 ligase regulates inflammation in atherosclerosis.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/30171069" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=26273&link_uid=30171069">reveal that FBXO46 is a crucial proteasomal regulator of FBXO31 and thereby prevents senescence in normal growth conditions</a>
|
||
<div id="gene-popper3" class="gene-rif-popper">Title: The SCF(FBXO46) ubiquitin ligase complex mediates degradation of the tumor suppressor FBXO31 and thereby prevents premature cellular senescence.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/27010866" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=26273&link_uid=27010866">we report the X-ray structure of the human FBxo3 ApaG domain, residues 278-407, at 2.0 A resolution</a>
|
||
<div id="gene-popper4" class="gene-rif-popper">Title: Crystal structure and interaction studies of the human FBxo3 ApaG domain.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/27365398" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=26273&link_uid=27365398">AIRE, which is phosphorylated on two specific residues near its N terminus, then binds to the F-box protein 3 (FBXO3) E3 ubiquitin ligase. In turn, this SCF(FBXO3) (SKP1-CUL1-F box) complex ubiquitylates AIRE, increases its binding to the positive transcription elongation factor b (P-TEFb), and potentiates its transcriptional activity.</a>
|
||
<div id="gene-popper5" class="gene-rif-popper">Title: FBXO3 Protein Promotes Ubiquitylation and Transcriptional Activity of AIRE (Autoimmune Regulator).</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/25721664" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=26273&link_uid=25721664">Fbxo3 promotes the proteasomal degradation of Smurf1. Fbxo3 promotes the poly-ubiquitination of Smurf1.</a>
|
||
<div id="gene-popper6" class="gene-rif-popper">Title: F-box protein Fbxo3 targets Smurf1 ubiquitin ligase for ubiquitination and degradation.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/24403578" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=26273&link_uid=24403578">Virulence factor NSs of rift valley fever virus recruits the FBXO3 to degrade subunit p62 of general transcription factor TFIIH.</a>
|
||
<div id="gene-popper7" class="gene-rif-popper">Title: Virulence factor NSs of rift valley fever virus recruits the F-box protein FBXO3 to degrade subunit p62 of general transcription factor TFIIH.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/23542741" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=26273&link_uid=23542741">controls TRAF adaptor stability to regulate inflammation</a>
|
||
<div id="gene-popper8" class="gene-rif-popper">Title: A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/20379614" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=26273&link_uid=20379614">Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)</a>
|
||
<div id="gene-popper9" class="gene-rif-popper">Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/18809579" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=26273&link_uid=18809579">Fbx3 formed SCF(Fbx3) ubiquitin ligase and promoted the degradation of HIPK2 and p300 by the ubiquitin-proteasome pathway</a>
|
||
<div id="gene-popper10" class="gene-rif-popper">Title: PML activates transcription by protecting HIPK2 and p300 from SCFFbx3-mediated degradation.</div>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
<div class="submit-genrif">
|
||
<span>Submit:</span>
|
||
<a href="/gene/submit-generif/?geneId=26273&sym=FBXO3&name=F-box protein 3&org=Homo sapiens">New GeneRIF</a>
|
||
<a href="/RefSeq/update.cgi?geneid=26273&symbol=FBXO3;task=fixpub">Correction</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-phenotypes">
|
||
<section class="rprt-section-header" id="phenotypes">
|
||
<h2 id="header-phenotypes">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-phenotypes .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Phenotypes</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Phenotype" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body info-phenotype">
|
||
<p class="nochild-link">
|
||
<a href="/gtr/tests/?term=FBXO3[gene]">Find tests for this gene in the NIH Genetic Testing Registry (GTR)</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/gap/PheGenI?tab=1&gene=26273">Review eQTL and phenotype association data in this region using PheGenI</a>
|
||
</p>
|
||
<div>
|
||
<h3 id="ebigwascatalog">EBI GWAS Catalog</h3>
|
||
<table class="jig-ncbigrid gtr-associated-cond" data-jigconfig="isPageable: true, pageSize: 10">
|
||
<thead>
|
||
<tr>
|
||
<th class="description">Description</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td>Genetics of coronary artery calcification among African Americans, a meta-analysis.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/23870195">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/23870195">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-variation">
|
||
<section class="rprt-section-header" id="variation">
|
||
<h2 id="header-variation">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-variation .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Variation</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.variation" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<p class="nochild-link">
|
||
<a href="/clinvar/?term=FBXO3[gene]" ref="log$=recordlinks">See variants in ClinVar</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/dbvar?LinkName=gene_dbvar&from_uid=26273" ref="log$=recordlinks">See studies and variants in dbVar</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/variation/view/?q=26273[geneid]&assm=GCF_000001405.25" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh37.p13)">See Variation Viewer (GRCh37.p13)</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/variation/view/?q=26273[geneid]" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh38)">See Variation Viewer (GRCh38)</a>
|
||
</p>
|
||
<set></set>
|
||
<set></set>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-HIV-1-interactions">
|
||
<section class="rprt-section-header" id="HIV-1-interactions">
|
||
<h2 id="header-HIV-1-interactions">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-HIV-1-interactions .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">HIV-1 interactions</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.HIV1_interactions" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div class="fgrid">
|
||
<h3 id="proteininteractions">Protein interactions</h3>
|
||
<table summary="protein interactions" class="jig-ncbigrid">
|
||
<thead>
|
||
<tr>
|
||
<th id="hivprotein">Protein</th>
|
||
<th id="gene-hivprotein">Gene</th>
|
||
<th id="hivinter">Interaction</th>
|
||
<th id="hivpub">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="hivprotein">
|
||
<a href="/protein/9629358">Tat</a>
|
||
</td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155871">tat</a>
|
||
</td>
|
||
<td headers="hivinter">HIV-1 Tat is identified to have a physical interaction with F-box protein 3 (FBXO3) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 22190034" href="/pubmed/22190034">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
<p class="withnote">
|
||
<a class="note" href="/genome/viruses/retroviruses/hiv-1/interactions/">Go to the HIV-1, Human Interaction Database </a>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
<div class="rprt-section gene-interactions">
|
||
<section class="rprt-section-header" id="interactions">
|
||
<h2 id="header-interactions">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-interactions .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Interactions</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Interactions" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<table summary="Gene Interaction" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/26273/data/interaction/',webserviceParams: 'p$l=Ajax&p$debugoutput=off', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th id="inter-prod">Products</th>
|
||
<th id="inter-interactant">Interactant</th>
|
||
<th id="inter-otherGene">Other Gene</th>
|
||
<th id="inter-compl">Complex</th>
|
||
<th id="inter-source">Source</th>
|
||
<th id="inter-pubs">Pubs</th>
|
||
<th id="inter-desc">Description</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody></tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-general-gene-info">
|
||
<section class="rprt-section-header" id="general-gene-info">
|
||
<h2 id="header-general-gene-info">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-gene-info .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">General gene information</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.General_Gene_Information" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
|
||
<div class="rprt-section-body" style="">
|
||
<div id="gene-markers">
|
||
<h3 id="markers">
|
||
<a class="jig-ncbitoggler">Markers</a>
|
||
</h3>
|
||
<div>
|
||
<ul class="marker odd">
|
||
<li class="marker">FBXO3_2462 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=280666%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=26273&link_uid=280666">UniSTS:280666</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">FBXO3 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=504684%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=26273&link_uid=504684">UniSTS:504684</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">SHGC-44450 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=14723%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=26273&link_uid=14723">UniSTS:14723</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">D1S3695 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=474273%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=26273&link_uid=474273">UniSTS:474273</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">D11S4719 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=9911%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=26273&link_uid=9911">UniSTS:9911</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">SGC44450 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=51159%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=26273&link_uid=51159">UniSTS:51159</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">A007J20 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=22243%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=26273&link_uid=22243">UniSTS:22243</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">WI-11454 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=20212%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=26273&link_uid=20212">UniSTS:20212</a></li></ul></li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div></div>
|
||
|
||
<div class="infosec">
|
||
<h3 id="homology">
|
||
<a class="jig-ncbitoggler-open">Homology</a>
|
||
</h3>
|
||
<ul class="geneinfo-subsec">
|
||
<li>
|
||
<a href="/gene/26273/ortholog/" id="ncbi-ortholog-link">NCBI Orthologs</a>
|
||
</li>
|
||
<a href="https://www.orthodb.org/?ncbi=26273" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=8178" target="_blank">
|
||
Orthologs from OrthoDB
|
||
</a>
|
||
</ul>
|
||
</div>
|
||
|
||
<!--<component id="Gene_InfoPathway"/>-->
|
||
|
||
<div class="infosec info-comment" id="info-comment">
|
||
<h3 id="CloneNames">
|
||
<a class="jig-ncbitoggler-open">Clone Names</a>
|
||
</h3>
|
||
<ul class="geneinfo-subsec">
|
||
<li>DKFZp564B092 </li>
|
||
</ul>
|
||
</div>
|
||
|
||
<div class="gene-ontology infosec">
|
||
<h3 id="gene-ontology">
|
||
<a class="jig-ncbitoggler-open">
|
||
<span>Gene Ontology</span>
|
||
</a>
|
||
<a target="_blank" href="http://www.ebi.ac.uk/GOA" class="g-ontology-src" title="Provided by GOA">Provided by GOA</a>
|
||
</h3>
|
||
<div class="ontology-tables">
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Function</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005515">enables protein binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
|
||
<div id="evidence-code-1-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/21145461,21516116,22190034,22632967,27705803,31515488,32296183,33961781" target="_blank" title="PubMed ID 21145461,21516116,22190034,22632967,27705803,31515488,32296183,33961781" ref="ordinalpos=1&ncbi_uid=26273&link_uid=21145461,21516116,22190034,22632967,27705803,31515488,32296183,33961781">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:1990756">enables ubiquitin-like ligase-substrate adaptor activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-2-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/26037928" target="_blank" title="PubMed ID 26037928" ref="ordinalpos=1&ncbi_uid=26273&link_uid=26037928">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0004842">enables ubiquitin-protein transferase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-3-0" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/10531035" target="_blank" title="PubMed ID 10531035" ref="ordinalpos=1&ncbi_uid=26273&link_uid=10531035">PubMed</a> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Process</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0031146">involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-1-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/26037928" target="_blank" title="PubMed ID 26037928" ref="ordinalpos=1&ncbi_uid=26273&link_uid=26037928">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0016567">involved_in protein ubiquitination</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-2-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0006508">involved_in proteolysis</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-3-1" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/10531035" target="_blank" title="PubMed ID 10531035" ref="ordinalpos=1&ncbi_uid=26273&link_uid=10531035">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0032496">involved_in response to lipopolysaccharide</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-4-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/26037928" target="_blank" title="PubMed ID 26037928" ref="ordinalpos=1&ncbi_uid=26273&link_uid=26037928">PubMed</a> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-config="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Component</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0019005">part_of SCF ubiquitin ligase complex</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-1-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/26037928" target="_blank" title="PubMed ID 26037928" ref="ordinalpos=1&ncbi_uid=26273&link_uid=26037928">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005737">is_active_in cytoplasm</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-2-2" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005829">located_in cytosol</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-3-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005654">located_in nucleoplasm</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-4-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005634">is_active_in nucleus</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-5-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/18809579" target="_blank" title="PubMed ID 18809579" ref="ordinalpos=1&ncbi_uid=26273&link_uid=18809579">PubMed</a> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-general-protein-info">
|
||
<section class="rprt-section-header" id="general-protein-info">
|
||
<h2 id="header-general-protein-info">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-protein-info .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">General protein information</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.General_Protein_Information" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<dl>
|
||
<dt>Preferred Names</dt>
|
||
<dd>F-box only protein 3</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt>Names</dt>
|
||
<dd>F-box protein FBX3</dd>
|
||
</dl>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-reference-sequences">
|
||
<section class="rprt-section-header" id="reference-sequences">
|
||
<h2 id="header-reference-sequences">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-reference-sequences .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">NCBI Reference Sequences (RefSeq)</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.NCBI_Reference_Sequences_RefS" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<p>
|
||
<span class="new-icon">NEW</span>
|
||
<strong>Try the new <a href="/datasets/tables/genes/?table_type=transcripts&ids=26273&utm_source=gene&utm_medium=referral&utm_campaign=refseq" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report." data-ga-category="refseq" data-ga-action="click_datasets_link" data-ga-label="transcript_table">Transcript table</a></strong>
|
||
</p>
|
||
<h3 class="genomerefseqs gene_std_toggler" id="refseqset-independent">
|
||
<a class="jig-ncbitoggler-open">RefSeqs maintained independently of Annotated
|
||
Genomes</a>
|
||
</h3>
|
||
<div class="genomerefseqs_slave">
|
||
<p class="desc"> These reference sequences exist independently of genome builds. <a href="#refseq-expl" id="expl-refseg">Explain</a></p>
|
||
<p id="refseq-expl"> These reference sequences are curated independently of the genome
|
||
annotation cycle, so their versions may not match the RefSeq versions in the current
|
||
genome build. Identify version mismatches by comparing the version of the RefSeq in
|
||
this section to the one reported in <a href="#geneGenomic regions, transcripts, and products">Genomic regions,
|
||
transcripts, and products</a> above. </p>
|
||
<h4 id="mrnaandproteins-p119498288">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/NM_012175.4">NM_012175.4</a> → <a href="/protein/NP_036307.2">NP_036307.2</a> F-box only protein 3 isoform 1</p>
|
||
<p>
|
||
<a href="/ipg/NP_036307.2/" ref="ncbi_uid=26273">See identical proteins and their annotated locations for NP_036307.2</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (1) encodes the longer isoform (1) which includes a highly acidic D/E-rich domain and two poly-R pieces at the C-terminus.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/BC039291, BC046110">BC039291, BC046110</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS7887.1">CCDS7887.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/B3KY16" ref="itool=Gene_FullReport&PrId=5380&uid=26273&nlmid=&db=gene">B3KY16</a>, <a href="https://www.uniprot.org/uniprot/D3DR05" ref="itool=Gene_FullReport&PrId=5380&uid=26273&nlmid=&db=gene">D3DR05</a>, <a href="https://www.uniprot.org/uniprot/Q86X90" ref="itool=Gene_FullReport&PrId=5380&uid=26273&nlmid=&db=gene">Q86X90</a>, <a href="https://www.uniprot.org/uniprot/Q9H0V2" ref="itool=Gene_FullReport&PrId=5380&uid=26273&nlmid=&db=gene">Q9H0V2</a>, <a href="https://www.uniprot.org/uniprot/Q9NUX2" ref="itool=Gene_FullReport&PrId=5380&uid=26273&nlmid=&db=gene">Q9NUX2</a>, <a href="https://www.uniprot.org/uniprot/Q9UK99" ref="itool=Gene_FullReport&PrId=5380&uid=26273&nlmid=&db=gene">Q9UK99</a></dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q59GS0" ref="itool=Gene_FullReport&PrId=5380&uid=26273&nlmid=&db=gene">Q59GS0</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000265651.3" ref="itool=Gene_FullReport&PrId=5380&uid=26273&nlmid=&db=gene">ENSP00000265651.3</a>, <a href="http://www.ensembl.org/id/ENST00000265651.8" ref="itool=Gene_FullReport&PrId=5380&uid=26273&nlmid=&db=gene">ENST00000265651.8</a></dd>
|
||
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_036307.2">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=398192">pfam04379</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">294</span> → <span class="cddto">383</span></dt>
|
||
<dd class="clearfix"> DUF525; ApaG domain</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=401332">pfam09346</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">121</span> → <span class="cddto">249</span></dt>
|
||
<dd class="clearfix"> SMI1_KNR4; SMI1 / KNR4 family (SUKH-1)</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=403981">pfam12937</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">13</span> → <span class="cddto">57</span></dt>
|
||
<dd class="clearfix"> F-box-like</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_033406.4">NM_033406.4</a> → <a href="/protein/NP_208385.1">NP_208385.1</a> F-box only protein 3 isoform 2</p>
|
||
<p>
|
||
<a href="/ipg/NP_208385.1/" ref="ncbi_uid=26273">See identical proteins and their annotated locations for NP_208385.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (2) is divergent from variant 1 at the 3' terminus. It encodes a C-terminal truncated isoform, which lacks the D/E-rich domain and poly-Rs, as compared to isoform 1.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC113192, AF176702, AL049629, BC017107, BC039291">AC113192, AF176702, AL049629, BC017107, BC039291</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS44566.1">CCDS44566.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q59GS0" ref="itool=Gene_FullReport&PrId=5380&uid=26273&nlmid=&db=gene">Q59GS0</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000408836.2" ref="itool=Gene_FullReport&PrId=5380&uid=26273&nlmid=&db=gene">ENSP00000408836.2</a>, <a href="http://www.ensembl.org/id/ENST00000448981.6" ref="itool=Gene_FullReport&PrId=5380&uid=26273&nlmid=&db=gene">ENST00000448981.6</a></dd>
|
||
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_208385.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=214864">smart00860</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">121</span> → <span class="cddto">249</span></dt>
|
||
<dd class="clearfix"> SMI1_KNR4; SMI1 / KNR4 family</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=315592">pfam12937</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">13</span> → <span class="cddto">57</span></dt>
|
||
<dd class="clearfix"> F-box-like; F-box-like</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=321352">cl01119</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">279</span> → <span class="cddto">404</span></dt>
|
||
<dd class="clearfix"> DUF525; ApaG domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
<h3 class="genomerefseqs gene_std_toggler" id="annotatedrefseq-title">
|
||
<a class="jig-ncbitoggler-open">RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08</a>
|
||
</h3>
|
||
<div class="genomerefseqs_slave">
|
||
<p class="desc"> The following sections contain reference sequences that belong to a
|
||
specific genome build. <a href="#" id="expl-genomes">Explain</a></p>
|
||
<p id="expl-genomes-desc" style="display:none">This section includes genomic Reference
|
||
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
|
||
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
|
||
assemblies. Model RNAs and proteins are also reported here.</p>
|
||
<h3 id="refseq-sequencedescription-p99259744">Reference GRCh38.p14 Primary Assembly</h3>
|
||
<h4 id="genomic-p99259744">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NC_000011.10 Reference GRCh38.p14 Primary Assembly</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>33740944..33774520 complement</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NC_000011.10?from=33740944&to=33774520&report=genbank&strand=true" ref="ordinalpos=1&ncbi_uid=26273&link_uid=NC_000011.10?from=33740944&to=33774520&report=genbank&strand=true">GenBank</a>, <a href="/nuccore/NC_000011.10?from=33740944&to=33774520&report=fasta&strand=true" ref="ordinalpos=1&ncbi_uid=26273&link_uid=NC_000011.10?from=33740944&to=33774520&report=fasta&strand=true">FASTA</a>, <a href="/nuccore/NC_000011.10?from=33735907&to=33779555&report=graph&content=5&strand=true" ref="ordinalpos=1&ncbi_uid=26273&link_uid=NC_000011.10?from=33735907&to=33779555&report=graph&content=5&strand=true">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="mrnaandproteins-p107671616">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011519980.2">XM_011519980.2</a> → <a href="/protein/XP_011518282.1">XP_011518282.1</a> F-box only protein 3 isoform X1</p>
|
||
<dl>
|
||
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011518282.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=282262">pfam04379</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">294</span> → <span class="cddto">383</span></dt>
|
||
<dd class="clearfix"> DUF525; Protein of unknown function (DUF525)</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=286436">pfam09346</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">121</span> → <span class="cddto">249</span></dt>
|
||
<dd class="clearfix"> SMI1_KNR4; SMI1 / KNR4 family (SUKH-1)</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=289689">pfam12937</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">13</span> → <span class="cddto">57</span></dt>
|
||
<dd class="clearfix"> F-box-like; F-box-like</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047426752.1">XM_047426752.1</a> → <a href="/protein/XP_047282708.1">XP_047282708.1</a> F-box only protein 3 isoform X3</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011519981.3">XM_011519981.3</a> → <a href="/protein/XP_011518283.1">XP_011518283.1</a> F-box only protein 3 isoform X2</p>
|
||
<p>
|
||
<a href="/ipg/XP_011518283.1/" ref="ncbi_uid=26273">See identical proteins and their annotated locations for XP_011518283.1</a>
|
||
</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q59GS0" ref="itool=Gene_FullReport&PrId=5380&uid=26273&nlmid=&db=gene">Q59GS0</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000431745.1" ref="itool=Gene_FullReport&PrId=5380&uid=26273&nlmid=&db=gene">ENSP00000431745.1</a>, <a href="http://www.ensembl.org/id/ENST00000534136.5" ref="itool=Gene_FullReport&PrId=5380&uid=26273&nlmid=&db=gene">ENST00000534136.5</a></dd>
|
||
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011518283.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=398192">pfam04379</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">294</span> → <span class="cddto">383</span></dt>
|
||
<dd class="clearfix"> DUF525; ApaG domain</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=401332">pfam09346</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">121</span> → <span class="cddto">249</span></dt>
|
||
<dd class="clearfix"> SMI1_KNR4; SMI1 / KNR4 family (SUKH-1)</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=403981">pfam12937</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">13</span> → <span class="cddto">57</span></dt>
|
||
<dd class="clearfix"> F-box-like</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h3 id="refseq-sequencedescription-p22998160">Alternate T2T-CHM13v2.0</h3>
|
||
<h4 id="genomic-p22998160">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NC_060935.1 Alternate T2T-CHM13v2.0</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>33877954..33911529 complement</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NC_060935.1?from=33877954&to=33911529&report=genbank&strand=true" ref="ordinalpos=1&ncbi_uid=26273&link_uid=NC_060935.1?from=33877954&to=33911529&report=genbank&strand=true">GenBank</a>, <a href="/nuccore/NC_060935.1?from=33877954&to=33911529&report=fasta&strand=true" ref="ordinalpos=1&ncbi_uid=26273&link_uid=NC_060935.1?from=33877954&to=33911529&report=fasta&strand=true">FASTA</a>, <a href="/nuccore/NC_060935.1?from=33872917&to=33916564&report=graph&content=5&strand=true" ref="ordinalpos=1&ncbi_uid=26273&link_uid=NC_060935.1?from=33872917&to=33916564&report=graph&content=5&strand=true">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="mrnaandproteins-p35854112">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054368394.1">XM_054368394.1</a> → <a href="/protein/XP_054224369.1">XP_054224369.1</a> F-box only protein 3 isoform X1</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054368396.1">XM_054368396.1</a> → <a href="/protein/XP_054224371.1">XP_054224371.1</a> F-box only protein 3 isoform X3</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054368395.1">XM_054368395.1</a> → <a href="/protein/XP_054224370.1">XP_054224370.1</a> F-box only protein 3 isoform X2</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q59GS0" ref="itool=Gene_FullReport&PrId=5380&uid=26273&nlmid=&db=gene">Q59GS0</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-related-sequences">
|
||
<section class="rprt-section-header" id="related-sequences">
|
||
<h2 id="header-related-sequences">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-related-sequences .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Related sequences</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Related_Sequences" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<table id="proteinTblId" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/26273/data/related-sequences/',webserviceParams: 'p$l=Ajax', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th colspan="2" id="rs-nucleo">Nucleotide</th>
|
||
<th rowspan="2" id="rs-protein">Protein</th>
|
||
</tr>
|
||
<tr>
|
||
<th id="rs-heading">Heading</th>
|
||
<th id="rs-heading-acc">Accession and Version</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody></tbody>
|
||
</table>
|
||
<table id="proteinTblId" class="jig-ncbigrid" data-jigconfig="isPageable:true, pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th class="proteinTblTh" rowspan="2" id="rs-prot-acc">Protein Accession</th>
|
||
<th class="proteinTblTh" colspan="2" id="rs-link">Links</th>
|
||
</tr>
|
||
<tr>
|
||
<th id="rs-genepept">GenPept Link</th>
|
||
<th id="rs-uniprot">UniProtKB Link</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="rs-prot-acc">Q9UK99.3</td>
|
||
<td headers="rs-link rs-genepept">
|
||
<a href="/protein/145559474" ref="ordinalpos=1&ncbi_uid=26273&link_uid=145559474">GenPept</a>
|
||
</td>
|
||
<td>
|
||
<a href="https://www.uniprot.org/uniprot/Q9UK99">UniProtKB/Swiss-Prot:Q9UK99</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-additional-links">
|
||
|
||
<section class="rprt-section-header" id="additional-links"><h2 id="header-additional-links"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-additional-links .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Additional links</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Additional_Links" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
|
||
|
||
<div class="rprt-section-body" style="">
|
||
|
||
|
||
<h3 class="withnote" id="genelinkout">
|
||
<a class="jig-ncbitoggler">Gene LinkOut</a>
|
||
</h3><div>
|
||
<p>The following <a href="https://www.ncbi.nlm.nih.gov/projects/linkout/index.html">LinkOut</a> resources are supplied by external providers. These providers are responsible for maintaining the links. </p>
|
||
<div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Chemical Information</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Interologous Interaction Database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://ophid.utoronto.ca/redirect/ncbi/human?proteins=26273" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=7911">
|
||
<span>Interologous Interaction Database</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>MilliporeSigma</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.sigmaaldrich.com/catalog/genes/FBXO3?lang=en&region=US" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=9978">
|
||
<span>Fbxo3 products</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Molecular Biology Databases</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Bgee database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.bgee.org/gene/ENSG00000110429" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=10418">
|
||
<span>FBXO3 gene expression</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>BioGPS</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://biogps.org/gene/26273/" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=5059">
|
||
<span>BioGPS</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>BioGRID Open Repository of CRISPR Screens (ORCS)</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://orcs.thebiogrid.org/Gene/26273" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=10164">
|
||
<span>BioGRID CRISPR Screen Phenotypes (24 hits/1408 screens)</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>CTD: Comparative Toxicogenomics Database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://ctdbase.org/detail.go?type=gene&acc=26273" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=7845">
|
||
<span>CTD: Comparative Toxicogenomics Database - FBXO3</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Domain Mapping of Disease Mutations</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://bioinf.umbc.edu/DMDM/gene_prot_page.php?id=26273" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=7642">
|
||
<span>FBXO3</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Eukaryotic Promoter Database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://epd.vital-it.ch/cgi-bin/get_doc?db=hgEpdNew&format=genome&entry=FBXO3_1" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=9624">
|
||
<span>FBXO3_1</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>GlyGen glycoinformatics resource</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://glygen.org/protein/Q9UK99" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=10227">
|
||
<span>GlyGen glycoinformatics resource</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Guide to Pharmacology</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=3233" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=8191">
|
||
<span>F-box protein 3 gene</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Human eFP Browser</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Nervous&modeInput=Absolute&primaryGene=26273" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Circulatory_Respiratory&modeInput=Absolute&primaryGene=26273" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Reproductive&modeInput=Absolute&primaryGene=26273" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li>Ingenuity Pathways Analysis</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://partnersolution.ingenuity.com/?cid=97ae3f91eab87a&p1=Entrez&p2=GV&s=&ipaUri=%2Fpa%2Fapi%2Fv2%2Fgeneview%3Fapplicationname%3DEntrez%26geneId%3D26273%26geneidtype%3Dentrezgene" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=5628">
|
||
<span>Ingenuity Pathways Analysis</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>InnateDB</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.innatedb.com/getGeneCard.do?id=38875" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=7894">
|
||
<span>InnateDB</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>InterMine</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.humanmine.org/humanmine/search?keyword=ENSG00000110429" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=9169">
|
||
<span>InterMine</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Kyoto Encyclopedia of Genes and Genomes</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.genome.jp/dbget-bin/www_bget?hsa:26273" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=5174">
|
||
<span>Kyoto Encyclopedia of Genes and Genomes</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>OMA Browser: Orthologous MAtrix</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN05326/" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN05322/" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN05321/" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>OrthoDB catalog of orthologs</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.orthodb.org/?ncbi=26273" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=8178">
|
||
<span>Orthologs</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>PhosphoSitePlus</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.phosphosite.org/entrezGeneIdAction.action?id=26273" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=7987">
|
||
<span>PhosphoSitePlus® - comprehensive post-translational modification resource</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>The Weizmann Institute of Science GeneCards and MalaCards databases</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=FBXO3" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=8598">
|
||
<span>GeneCard for FBXO3</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Research Materials</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="order-rsc"></span>Addgene Non-profit plasmid repository</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://addgene.org//browse/gene/26273" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=5304">
|
||
<span>Get Plasmids - Addgene</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>Bio-Techne</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/fbxo3/proteins-enzymes?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=proteins" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>FBXO3 Proteins</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/fbxo3/antibodies?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=antibodies" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>FBXO3 Antibodies</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/fbxo3/lysates?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=lysates" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>FBXO3 Lysates</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li>ExactAntigen/Labome</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.labome.com/gene/human/FBXO3-antibody.html" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=5753">
|
||
<span>reagents</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GenScript latest version of gene cDNA ORF Clone</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.genscript.com/gene/26273" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=8012">
|
||
<span>GenScript latest version of gene cDNA ORF Clone</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GeneCopoeia Inc.</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=26&field=5&key=26273" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order TALEN/CRISPR clones</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?tax_id=9606&field=5&prt=16&key=26273" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order miRNA target clones</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=1&field=5&key=26273" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order full-length ORF clone</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GeneTex Inc</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genetex.com/Product/Search?geneid=26273&type=01&page=1" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=8117">
|
||
<span>Find Quality Antibodies</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>Kazusa DNA Research Institute</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.kazusa.or.jp/kop/dsearch/symsearch.cgi?keyword=FBXO3;" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=3267">
|
||
<span>Kazusa DNA Research Institute</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>OriGene</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.origene.com/search?q=FBXO3" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=7994">
|
||
<span>Order FBXO3 cDNA clone/Protein/Antibody/RNAi</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Tools</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>GeneMANIA</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://genemania.org/link?o=9606&g=26273" ref="itool=Gene_FullReport&uid=26273&nlmid=&db=gene&log$=linkoutlink&PrId=7529">
|
||
<span>GeneMANIA</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="urls-in-genombrowser" style="display:none">
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div><input type="hidden" class="section_status_input" name="status_checked" id="status_checked" value="" /><input type="hidden" class="section_status_input" name="status_open" id="status_open" value="summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links" /><input type="hidden" class="section_status_input" name="status_exist" id="status_exist" value="summary,context,region,expression,bibliography,phenotypes,variation,hiv,interactions,geneInfo,proteinInfo,refSeq,related,links" /><input type="hidden" class="section_status_input" name="status_closed" id="status_closed" value="" /><meta name="status_checked" content="" class="meta_section_status" /><meta name="status_open" content="summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links" class="meta_section_status" /><meta name="status_exist" content="summary,context,region,expression,bibliography,phenotypes,variation,hiv,interactions,geneInfo,proteinInfo,refSeq,related,links" class="meta_section_status" /><meta name="status_closed" content="" class="meta_section_status" /><script type="text/javascript">
|
||
|
||
var section_status_meta = {
|
||
'status_checked': '',
|
||
'status_open': 'summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links',
|
||
'status_exist': 'summary,context,region,expression,bibliography,phenotypes,variation,hiv,interactions,geneInfo,proteinInfo,refSeq,related,links',
|
||
'status_closed': ''
|
||
};
|
||
|
||
|
||
/*
|
||
for (var o in section_status_meta) {
|
||
var meta=document.createElement('meta');
|
||
meta.name = o;
|
||
meta.content = section_status_meta[o];
|
||
var attr = document.createAttribute('data-ignore-limit');
|
||
attr.value = 'true';
|
||
meta.setAttributeNode(attr);
|
||
document.getElementsByTagName('head')[0].appendChild(meta);
|
||
}
|
||
*/
|
||
|
||
|
||
var __ncbi_sg_pingCallbacks_render_gene = function (data, evtObj, type) {
|
||
// data looks like {jsevent: "click", "link_id": "foo", ...}
|
||
// evtObj is the JS event object
|
||
// type is either "stat" (for applog) or "ga"
|
||
var extraData = {};
|
||
if (type == "stat") {
|
||
for (var o in section_status_meta) {
|
||
extraData[o] = section_status_meta[o];
|
||
}
|
||
|
||
return extraData;
|
||
|
||
}
|
||
}
|
||
|
||
|
||
</script></div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last" id="sidebar_tabular">
|
||
<!-- sidebar close/hide button-->
|
||
<div class="ui-helper-clearfix">
|
||
<a href="#" id="sidecontent_2_pullout" style="float:right;" class="sidecontentpullout_local collapse_button"><span>Hide sidebar >></span></a>
|
||
</div>
|
||
<!-- end sidebar close/hide button-->
|
||
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div id="gene-sidebar">
|
||
<div>
|
||
<div class="portlet brieflink dis-table-of-contents">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Table of contents</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_TableOfContents" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li class="">
|
||
<a href="#summary">Summary</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#genomic-context">Genomic context</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#genomic-regions-transcripts-products">Genomic regions, transcripts, and products</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#gene-expression">Expression</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#bibliography">Bibliography</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#phenotypes">Phenotypes</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#variation">Variation</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#HIV-1-interactions">HIV-1 interactions</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#interactions">Interactions</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#general-gene-info">General gene information</a>
|
||
<div class="subsection-links"><a href="#gene-markers">Markers</a>, <a href="#CloneNames">Clone Names</a>, <a href="#homology">Homology</a>, <a href="#gene-ontology">Gene Ontology</a></div>
|
||
</li>
|
||
<li class="">
|
||
<a href="#general-protein-info">General protein information</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#reference-sequences">NCBI Reference Sequences (RefSeq)</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#related-sequences">Related sequences</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#additional-links">Additional links</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-genomesbrowser brieflink dis-genomesbrowser">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Genome Browsers</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GenomeBrowsers.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_GenomeBrowsers" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GenomeBrowsers.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="#">Loading...</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet dis-related-info brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related information</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="discovery_db_links" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content DiscoveryDbLinks">
|
||
<ul>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clone/order/gene/26273" ref="log$=recordlinks">Order cDNA clone</a>
|
||
<div class="brieflinkpop offscreen_noflow">Order cDNA clone</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_alltarget_list&from_uid=26273" ref="log$=recordlinks">BioAssay by Target (List)</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioAssays related to the gene by protein target or RNAi target</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="//pubchem.ncbi.nlm.nih.gov/assay/bioactivity.html?geneid=26273" ref="log$=recordlinks">BioAssay by Target (Summary)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Summarized PubChem Data on the gene, showing the active data by default</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_target&from_uid=26273" ref="log$=recordlinks">BioAssay, by Gene target</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem BioAssays done on the Gene target</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_rnai_active&from_uid=26273" ref="log$=recordlinks">BioAssays, RNAi Target, Active</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioAssays that contain the gene as the target of a RNAi reagent, which is identified as a hit in a RNAi screening and flagged as "active" in the corresponding BioAssay record</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_rnai&from_uid=26273" ref="log$=recordlinks">BioAssays, RNAi Target, Tested</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioAssays that contain the gene as the target of a RNAi reagent</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/bioproject?LinkName=gene_bioproject&from_uid=26273" ref="log$=recordlinks">BioProjects</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioProjects related to a gene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/CCDS/CcdsBrowse.cgi?REQUEST=GENEID&DATA=26273" ref="log$=recordlinks">CCDS</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to CCDS</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar&from_uid=26273" ref="log$=recordlinks">ClinVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/cdd?LinkName=gene_cdd&from_uid=26273" ref="log$=recordlinks">Conserved Domains</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related CDD</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/dbvar?LinkName=gene_dbvar&from_uid=26273" ref="log$=recordlinks">dbVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link from Gene to dbVar</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc&from_uid=26273" ref="log$=recordlinks">Full text in PMC</a>
|
||
<div class="brieflinkpop offscreen_noflow">PMC links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc_nucleotide&from_uid=26273" ref="log$=recordlinks">Full text in PMC_nucleotide</a>
|
||
<div class="brieflinkpop offscreen_noflow">Full text in PubMedCentral identified from shared sequence links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/sparcle?LinkName=gene_sparcle&from_uid=26273" ref="log$=recordlinks">Functional Class</a>
|
||
<div class="brieflinkpop offscreen_noflow">Functional class of the sequence domain architecture</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_neighbors&from_uid=26273" ref="log$=recordlinks">Gene neighbors</a>
|
||
<div class="brieflinkpop offscreen_noflow">Overlapping genes and two nearest non-overlapping genes on either side</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_h3k4me3&from_uid=26273" ref="log$=recordlinks">Genes with a similar H3K4me3 profile</a>
|
||
<div class="brieflinkpop offscreen_noflow">Genes with a similar profile of promoter-activating H3K4me3 modifications across several tissue types</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/genome?LinkName=gene_genome&from_uid=26273" ref="log$=recordlinks">Genome</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Genome</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/geoprofiles?LinkName=gene_geoprofiles&from_uid=26273" ref="log$=recordlinks">GEO Profiles</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related GEO</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests/?term=26273[geneid]" ref="log$=recordlinks">GTR</a>
|
||
<div class="brieflinkpop offscreen_noflow">Tests for this gene in the NIH Genetic Testing Registry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/homologene?LinkName=gene_homologene&from_uid=26273" ref="log$=recordlinks">HomoloGene</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related HomoloGene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore&from_uid=26273" ref="log$=recordlinks">Nucleotide</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related Nucleotide entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/omim?LinkName=gene_omim&from_uid=26273" ref="log$=recordlinks">OMIM</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related OMIM entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/probe?LinkName=gene_probe&from_uid=26273" ref="log$=recordlinks">Probe</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Probe entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein&from_uid=26273" ref="log$=recordlinks">Protein</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related protein entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pccompound?LinkName=gene_pccompound&from_uid=26273" ref="log$=recordlinks">PubChem Compound</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem Compounds</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcsubstance?LinkName=gene_pcsubstance&from_uid=26273" ref="log$=recordlinks">PubChem Substance</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem Substances</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed&from_uid=26273" ref="log$=recordlinks">PubMed</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related PubMed entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_rif&from_uid=26273" ref="log$=recordlinks">PubMed (GeneRIF)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related PubMed article from GeneRIFs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_citedinomim&from_uid=26273" ref="log$=recordlinks">PubMed (OMIM)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Gene links to PubMed derived from omim_pubmed_cited links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_pmc_nucleotide&from_uid=26273" ref="log$=recordlinks">PubMed(nucleotide/PMC)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Citations in PubMed identified from shared sequence and PMC links.</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein_refseq&from_uid=26273" ref="log$=recordlinks">RefSeq Proteins</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Protein RefSeqs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore_refseqrna&from_uid=26273" ref="log$=recordlinks">RefSeq RNAs</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeq RNAs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/snp?LinkName=gene_snp&from_uid=26273" ref="log$=recordlinks">SNP</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related SNP records</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/taxonomy?LinkName=gene_taxonomy&from_uid=26273" ref="log$=recordlinks">Taxonomy</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related taxonomy entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/variation/view/?q=26273[geneid]" ref="log$=recordlinks">Variation Viewer</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Variants</div>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet dis-links-to-other-res brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Links to other resources</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_LinksTwo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:13582">HGNC</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.ensembl.org/id/ENSG00000110429">Ensembl</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.alliancegenome.org/gene/HGNC:13582">AllianceGenome</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=geneid&org=9606&l=26273">AceView</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position=NM_033406">UCSC</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://genecollections.nci.nih.gov/MGC/?ORG=Hs&LIST=BC046110">MGC</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://phgkb.cdc.gov/PHGKB/huGEPedia.action?firstQuery=FBXO3&geneID=26273&typeOption=gene&which=2&pubOrderType=pubD&typeSubmit=GO&check=y">HuGE Navigator</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.genome.jp/dbget-bin/www_bget?hsa:26273">KEGG</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-general-info">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>General information</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_GeneralInfo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="/pmc/?term=PMC4383897+OR+PMC3013746+OR+PMC1761442+OR+PMC539985">About Gene</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3840">FAQ</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://ftp.ncbi.nlm.nih.gov/gene/">FTP site</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3841/">Help</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3842/">My NCBI help</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK21085/">NCBI Handbook</a>
|
||
</li>
|
||
<li>
|
||
<a href="/gene/statistics/">Statistics</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-related-sites">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related sites</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedSites.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_RelatedSites" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedSites.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/BLAST">BLAST</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/genome">Genome</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/bioproject">BioProject</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/genome/gdv/">Genome Data Viewer</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/geo">GEO</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/omim">OMIM</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/probe">Probe</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/RefSeq">RefSeq</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-feedback">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Feedback</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Feedback.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_Feedback" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Feedback.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://support.ncbi.nlm.nih.gov/ics/support/ticketnewwizard.asp?style=classic&deptID=28049">Contact Help Desk</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/RefSeq/update.cgi?geneid=26273&symbol=FBXO3">Submit Correction</a>
|
||
</li>
|
||
<li>
|
||
<a href="/gene/submit-generif?geneId=26273&sym=FBXO3&name=F-box protein 3&org=Homo sapiens">Submit GeneRIF</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-subscription">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Subscription</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Subscription.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_Subscription" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Subscription.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/mailman/listinfo/refseq-announce">RefSeq</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
<!-- <component id="Gene_RVFullReport.Gene_RightColMenuLinks"/>-->
|
||
<div class="portlet">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Recent activity</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="recent_activity" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<div id="HTDisplay" class="">
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.Cmd" sid="1" type="hidden" />
|
||
<div class="action">
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory" cmd="ClearHT" href="?cmd=ClearHT&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory">
|
||
Clear
|
||
</a>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOn" cmd="HTOff" href="?cmd=HTOff&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle">
|
||
Turn Off
|
||
</a>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" sid="2" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOff" cmd="HTOn" href="?cmd=HTOn&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle">
|
||
Turn On
|
||
</a>
|
||
</div>
|
||
<ul id="activity">
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67c9f39af4a390645eacbea8">FBXO3 F-box protein 3 [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">FBXO3 F-box protein 3 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:26273</div></div>
|
||
<div class="tertiary">Gene</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=2" href="/portal/utils/pageresolver.fcgi?recordid=67c9f398f4a390645eacb675">F-box only protein 3 isoform 1 [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">F-box only protein 3 isoform 1 [Homo sapiens]<div class="brieflinkpopdesc">gi|15812186|ref|NP_036307.2|</div></div>
|
||
<div class="tertiary">Protein</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=3" href="/portal/utils/pageresolver.fcgi?recordid=67c9f396b15b832ebc7cac26">FBXO11 F-box protein 11 [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">FBXO11 F-box protein 11 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:80204</div></div>
|
||
<div class="tertiary">Gene</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=4" href="/portal/utils/pageresolver.fcgi?recordid=67c9f394f4a390645eaca579">F-box only protein 11 isoform 1 [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">F-box only protein 11 isoform 1 [Homo sapiens]<div class="brieflinkpopdesc">gi|30089926|ref|NP_079409.3|</div></div>
|
||
<div class="tertiary">Protein</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=5" href="/portal/utils/pageresolver.fcgi?recordid=67c9f393f4a390645eac9ea8">fibrillin-2 precursor [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">fibrillin-2 precursor [Homo sapiens]<div class="brieflinkpopdesc">gi|66346695|ref|NP_001990.2|</div></div>
|
||
<div class="tertiary">Protein</div>
|
||
</li>
|
||
</ul>
|
||
<p class="HTOn">Your browsing activity is empty.</p>
|
||
<p class="HTOff">Activity recording is turned off.</p>
|
||
<p id="turnOn" class="HTOff">
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryOn" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryOn" cmd="HTOn" href="?cmd=HTOn&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryOn">Turn recording back on</a>
|
||
</p>
|
||
<a class="seemore" href="/sites/myncbi/recentactivity">See more...</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div id="NCBIFooter_dynamic">
|
||
<!--<component id="NCBIBreadcrumbs"/>
|
||
<component id="NCBIHelpDesk"/>-->
|
||
<noscript><img alt="" src="/stat?jsdisabled=true&ncbi_app=entrez&ncbi_db=gene&ncbi_pdid=full_report&ncbi_phid=CE895D637C9E49C10000000000560052" /></noscript>
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||
</div>
|
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|
||
<div xmlns="http://www.w3.org/1999/xhtml" class="footer" id="footer" xml:base="http://127.0.0.1/sites/static/header_footer/">
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<section class="icon-section">
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<div id="icon-section-header" class="icon-section_header">Follow NCBI</div>
|
||
<div class="grid-container container">
|
||
<div class="icon-section_container">
|
||
<a class="footer-icon" id="footer_twitter" href="https://twitter.com/ncbi" aria-label="Twitter">
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<svg xmlns="http://www.w3.org/2000/svg" width="40" height="40" viewBox="0 0 40 40" fill="none">
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<title>Twitter</title>
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<g id="twitterx1008">
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<a class="footer-icon" id="footer_facebook" href="https://www.facebook.com/ncbi.nlm" aria-label="Facebook"><svg xmlns="http://www.w3.org/2000/svg" data-name="Layer 1" viewBox="0 0 300 300">
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<title>Facebook</title>
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