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<div class="search"><div class="search_form"><label for="database" class="offscreen_noflow">Search database</label><select id="database"><optgroup label="Recent"><option value="pubmed">PubMed</option><option value="clinvar">ClinVar</option><option value="medgen">MedGen</option><option value="books" class="last">Books</option></optgroup><optgroup label="All"><option value="gquery">All Databases</option><option value="assembly" data-ac_dict="assembly">Assembly</option><option value="biocollections">Biocollections</option><option value="bioproject">BioProject</option><option value="biosample">BioSample</option><option value="books">Books</option><option value="clinvar">ClinVar</option><option value="cdd">Conserved Domains</option><option value="gap">dbGaP</option><option value="dbvar">dbVar</option><option value="gene" selected="selected" data-ac_dict="gene">Gene</option><option value="genome" data-ac_dict="genome">Genome</option><option value="gds">GEO DataSets</option><option value="geoprofiles">GEO Profiles</option><option value="gtr">GTR</option><option value="ipg">Identical Protein Groups</option><option value="medgen">MedGen</option><option value="mesh">MeSH</option><option value="nlmcatalog">NLM Catalog</option><option value="nuccore" data-ac_dict="nuccore">Nucleotide</option><option value="omim">OMIM</option><option value="pmc">PMC</option><option value="protein" data-ac_dict="protein">Protein</option><option value="proteinclusters">Protein Clusters</option><option value="protfam">Protein Family Models</option><option value="pcassay">PubChem BioAssay</option><option value="pccompound">PubChem Compound</option><option value="pcsubstance">PubChem Substance</option><option value="pubmed">PubMed</option><option value="snp">SNP</option><option value="sra">SRA</option><option value="structure">Structure</option><option value="taxonomy">Taxonomy</option><option value="toolkit">ToolKit</option><option value="toolkitall">ToolKitAll</option><option value="toolkitbookgh">ToolKitBookgh</option></optgroup></select><div class="nowrap"><label for="term" class="offscreen_noflow" accesskey="/">Search term</label><div class="nowrap"><input type="text" name="term" id="term" title="Search Gene. Use up and down arrows to choose an item from the autocomplete." value="" class="jig-ncbiclearbutton jig-ncbiautocomplete" data-jigconfig="dictionary:'gene',disableUrl:'NcbiSearchBarAutoComplCtrl'" autocomplete="off" data-sbconfig="ds:'no',pjs:'yes',afs:'yes'" /></div><button id="search" type="submit" class="button_search nowrap" cmd="go">Search</button></div></div><ul class="searchlinks inline_list"><set></set><li><a href="/gene/advanced">Advanced</a></li><li class="help"><a id="help" class="jig-ncbihelpwindow" target="ncbihelp" name="help" href="/books/NBK3841/">Help</a></li></ul></div>
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<div class="facet_cont" data-db="gene" data-default_grps="fg_gene-sources,fg_categories,fg_sequence-content,fg_status" data-sd="db:'gene',op:'select',term:'',qk:'7508',linkname:'',idsfromresult:'2580',extra:''"><ul class="facet" data-filter_id="gene-sources" id="_gene-sources"><li class="filter_grp "><div class="clearfix"><h3>Gene sources</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="genomic">Genomic</a></li></ul></li></ul><ul class="facet" data-filter_id="categories" id="_categories"><li class="filter_grp "><div class="clearfix"><h3>Categories</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="alt-splicing">Alternatively spliced</a></li><li class="fil_val"><a href="#" data-value_id="annotated-genes">Annotated genes</a></li><li class="fil_val"><a href="#" data-value_id="gene-type-protein-coding">Protein-coding</a></li></ul></li></ul><ul class="facet" data-filter_id="sequence-content" id="_sequence-content"><li class="filter_grp "><div class="clearfix"><h3>Sequence content</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="seq-ccds">CCDS</a></li><li class="fil_val"><a href="#" data-value_id="seq-ensembl">Ensembl</a></li><li class="fil_val"><a href="#" data-value_id="refseq">RefSeq</a></li></ul></li></ul><ul class="facet" data-filter_id="status" id="_status"><li class="filter_grp "><div class="clearfix"><h3>Status</h3><a href="#" data-value_id="" class="clear clear_show">Clear</a></div><ul><li class="fil_val selected"><a href="#" data-value_id="current-only">Current</a><span class="fcount">(1)</span></li></ul></li></ul><div id="chr-location-facet-wrapper" data-bid="MCID_67ca033069195c35ad769cba" data-hid="MCID_67c90f2d64f30b25346ccae2" data-qky="7508" class="disabled" style="display:none"><ul class="facet" data-filter_id="chromosomal-region" id="_chromosomal-region" data-of="yes"><li class="filter_grp of_grp"><div class="clearfix"><h3>Chromosome locations</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><a id="facet_ofchromosomal-region" href="#facet_of_divchromosomal-region" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'middle left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '375px'" data-value_id="fetch_more">more...</a><div id="facet_of_divchromosomal-region" style="display:none;" class="of_popup"><h4>Chromosome locations</h4><label for="organism-filter" style="width:100%;margin-bottom:.2em;" class="">Select an organism by typing or scrolling</label><input type="text" placeholder="Enter text to narrow down the list" id="organism-filter" style="width:98%;" autocomplete="off" /><br /><div id="chr-region-tax-list"><select id="of_chromosomal-region" size="9" class="chr-region-tax-list" style="width:100%;"></select></div><div id="chr-location-info-ctrl" data-disabled="disabled"><div class="chr-field"><label for="chr-name">Chromosome</label><br /><select id="chr-name" class="chr-field" disabled="disabled"></select></div><div class="chr-field"><label for="chr-from">From</label><br /><input type="text" name="chr-from" id="chr-from" disabled="disabled" class="chr-field" /></div><div class="chr-field"><label for="chr-to">To</label><br /><input type="text" name="chr-to" id="chr-to" disabled="disabled" class="chr-field" /></div></div><div class="actions clearfix"><button class="jig-ncbibutton of_add apply-chr" data-jigconfig="'color': 'ui-ncbibutton-blue'">Apply</button></div></div></ul></li></ul></div><ul class="facet facet_reset"><li><a href="#" data-value_id="reset">Clear all</a></li></ul><ul class="facet_tools"><li><a id="more_filter_groups_link" href="#more_filter_groups" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'top left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '180px'">
Show additional filters</a></li><div id="more_filter_groups" style="display:none;" class="facets_dialog"><button class="ui-ncbipopper-close-button ui-ncbipopper-close-button-generated ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-blue" generated="true" role="button" aria-disabled="false"><span class="ui-button-text">x</span></button><h4>Additional filters</h4><ul class="filter_groups_more facet"><li><input type="checkbox" id="fg_gene-sources" /><label for="fg_gene-sources">Gene sources</label></li><li><input type="checkbox" id="fg_categories" /><label for="fg_categories">Categories</label></li><li><input type="checkbox" id="fg_sequence-content" /><label for="fg_sequence-content">Sequence content</label></li><li><input type="checkbox" id="fg_status" /><label for="fg_status">Status</label></li><li><input type="checkbox" id="fg_chromosomal-region" /><label for="fg_chromosomal-region">Chromosome locations</label></li><li><input id="fg_field_search" type="checkbox" /><label for="fg_field_search">Search fields</label></li></ul><div class="actions clearfix"><button class="filter_groups_more_apply jig-ncbibutton primary-action" id="filter_groups_apply" data-jigconfig="'color': 'ui-ncbibutton-blue'">Show</button></div></div></ul><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetsUrlFrag" sid="1" type="hidden" value="filters=current-only" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetSubmitted" sid="1" type="hidden" value="false" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.BMFacets" sid="1" type="hidden" value="" /></div>
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<h1 class="title" id="gene-name"><span class="gn" style="padding-right:.5em;">GAK</span> cyclin G associated kinase [ <em class="tax">Homo sapiens</em> (human)
]
</h1>
<span class="geneid">Gene ID: 2580, updated on
4-Mar-2025</span>
</div>
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<div class="rprt-section gene-summary">
<section class="rprt-section-header" id="summary">
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<div id="summaryDiv" class="section">
<dl id="summaryDl">
<dt class="noline"> Official
Symbol</dt>
<dd class="noline">GAK<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
<dt> Official
Full Name</dt>
<dd>cyclin G associated kinase<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
<dt>Primary source</dt>
<dd>
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:4113" data-gblink-text="Ensembl">HGNC:HGNC:4113</a>
</dd>
<dt>See related</dt>
<dd>
<a href="http://www.ensembl.org/id/ENSG00000178950" data-gblink-text="Ensembl" class="genome-browser-link" data-genome-browser-link-sort="5" data-gb-url="http://www.ensembl.org/loc/ENSG00000178950">Ensembl:ENSG00000178950</a>
<a href="https://www.ncbi.nlm.nih.gov/omim/602052" data-gblink-text="Ensembl" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=602052">MIM:602052;</a>
<a href="https://www.alliancegenome.org/gene/HGNC:4113" data-gblink-text="Ensembl" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=HGNC:4113">AllianceGenome:HGNC:4113</a>
</dd>
<dt>Gene type</dt>
<dd>protein coding</dd>
<dt>RefSeq status</dt>
<dd>VALIDATED</dd>
<dt>Organism</dt>
<dd class="tax">
<a href="/Taxonomy/Browser/wwwtax.cgi?id=9606" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=9606">Homo sapiens</a>
</dd>
<dt>Lineage</dt>
<dd class="tax">Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo</dd>
<dt>Also known as</dt>
<dd>DNAJ26; DNAJC26</dd>
<dt>Summary</dt>
<dd>In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]</dd>
<dt>Expression</dt>
<dd>Ubiquitous expression in testis (RPKM 16.1), colon (RPKM 15.2) and 25 other tissues <a href="#gene-expression">See more</a></dd>
<dt>Orthologs</dt>
<dd class="ortholog-links">
<a href="https://www.ncbi.nlm.nih.gov/gene/231580">mouse</a>
<a href="/gene/2580/ortholog/">all</a>
</dd>
<dt style="padding-top:.5em;">
<span class="new-icon">NEW</span>
</dt>
<dd style="padding-top:.5em;">
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/2580/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="gene_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Gene table</a></strong>
<br />
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/2580/products/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="transcript_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Transcript table</a></strong>
</dd>
</dl>
</div>
</div>
</div>
<div class="rprt-section gene-genomic-context">
<section class="rprt-section-header" id="genomic-context">
<h2 id="header-genomic-context">
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<span class="ui-ncbitoggler-master-text">Genomic context</span>
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</h2>
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</section>
<div class="rprt-section-body">
<div class="gc_cont">
<div class="gt_cont_contents">
<div style="float:right"><span>See GAK in </span><a href="/genome/gdv/?context=gene&amp;acc=2580" class="link-to-gdv genome-browser-link" data-genome-browser-link-sort="1" data-acc="GCF_000001405.40">Genome Data Viewer</a> </div>
<dl class="dl-chr-info" style="float:left;margin-top:0;">
<dt>Location: </dt>
<dd>
<span style="display:inline-block;">4p16.3</span>
</dd>
</dl>
</div>
<dl class="dl-chr-info exon-count">
<dt>Exon count: </dt>
<dd>33</dd>
</dl>
<div class="ui-ncbigrid-outer-div" id="genomic-context-tbl-location">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-jigconfig="">
<thead>
<tr>
<th style="max-width:15%">Annotation release</th>
<th style="max-width:10%">Status</th>
<th>Assembly</th>
<th>
<span title="Chromosome">Chr</span>
</th>
<th>Location</th>
</tr>
</thead>
<tbody>
<tr>
<td>RS_2024_08</td>
<td>current</td>
<td>GRCh38.p14 (<a href="/assembly/GCF_000001405.40/" ref="ncbi_uid=2580&amp;link_uid=GCF_000001405.40">GCF_000001405.40</a>)</td>
<td>4</td>
<td>NC_000004.12 (849277..932316, complement) </td>
</tr>
<tr>
<td>RS_2024_08</td>
<td>current</td>
<td>T2T-CHM13v2.0 (<a href="/assembly/GCF_009914755.1/" ref="ncbi_uid=2580&amp;link_uid=GCF_009914755.1">GCF_009914755.1</a>)</td>
<td>4</td>
<td>NC_060928.1 (847030..930388, complement) </td>
</tr>
<tr>
<td>RS_2024_09</td>
<td>previous assembly</td>
<td>GRCh37.p13 (<a href="/assembly/GCF_000001405.25/" ref="ncbi_uid=2580&amp;link_uid=GCF_000001405.25">GCF_000001405.25</a>)</td>
<td>4</td>
<td>NC_000004.11 (843065..926104, complement) </td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
<p class="withnote margin_t2em"><strong>Chromosome 4 - NC_000004.12</strong><img usemap="#nbrMap2580_568815594" border="0" alt="Genomic Context describing neighboring genes" src="/gutils/geneneighb.fcgi?geneid=2580&amp;nuc_gi=568815594&amp;n0=CPLX1&amp;n1=LOC105374339&amp;n2=LOC127399715&amp;n3=LOC127399716&amp;n4=LOC127399717&amp;n5=LOC127399718&amp;n6=LOC129991958&amp;n7=LOC129991959&amp;n8=LOC129991960&amp;n9=LOC129991961&amp;n10=LOC127399719&amp;n11=LOC129991962&amp;n12=LOC127399720&amp;n13=LOC127399721&amp;n14=LOC105374340&amp;n15=GAK&amp;n16=LOC126806940&amp;n17=LOC105374341&amp;n18=LOC126806941&amp;n19=LOC127399722&amp;n20=LOC127399723&amp;n21=LOC127399724&amp;n22=LOC127399725&amp;n23=LOC129991963&amp;n24=LOC129991964&amp;n25=LOC129991965&amp;n26=TMEM175&amp;n27=LOC129991966&amp;n28=LOC127399726&amp;n29=DGKQ&amp;n30=LOC129661206&amp;n31=LOC127399727&amp;n32=LOC127399728&amp;n33=LOC124900645&amp;n34=LOC127399729" /><map name="nbrMap2580_568815594" id="nbrMap2580_568815594">
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC105374339')" onMouseOut="hidetip()" coords="7,23,87,31" alt="Neighboring gene uncharacterized LOC105374339" href="/gene/105374339" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr4:781743-782244')" onMouseOut="hidetip()" coords="8,35,78,43" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:781743-782244" href="/gene/127399715" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr4:782245-782744')" onMouseOut="hidetip()" coords="9,47,79,55" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:782245-782744" href="/gene/127399716" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr4:783251-783750')" onMouseOut="hidetip()" coords="11,59,81,67" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:783251-783750" href="/gene/127399717" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:784983-785792')" onMouseOut="hidetip()" coords="14,71,84,79" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:784983-785792" href="/gene/127399718" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 15110')" onMouseOut="hidetip()" coords="18,83,88,91" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15110" href="/gene/129991958" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 21135')" onMouseOut="hidetip()" coords="20,95,90,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21135" href="/gene/129991959" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 21136')" onMouseOut="hidetip()" coords="21,107,91,115" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21136" href="/gene/129991960" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 21137')" onMouseOut="hidetip()" coords="29,119,99,127" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21137" href="/gene/129991961" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr4:793259-793758')" onMouseOut="hidetip()" coords="30,131,100,139" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:793259-793758" href="/gene/127399719" />
<area shape="rect" onMouseOver="showtip(this,event,'complexin 1')" onMouseOut="hidetip()" coords="37,143,142,151" alt="Neighboring gene complexin 1" href="/gene/10815" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 15111')" onMouseOut="hidetip()" coords="80,35,150,43" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15111" href="/gene/129991962" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr4:823745-824262')" onMouseOut="hidetip()" coords="88,23,158,31" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:823745-824262" href="/gene/127399720" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr4:824263-824778')" onMouseOut="hidetip()" coords="89,47,159,55" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:824263-824778" href="/gene/127399721" />
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC105374340')" onMouseOut="hidetip()" coords="107,59,182,67" alt="Neighboring gene uncharacterized LOC105374340" href="/gene/105374340" />
<area shape="rect" onMouseOver="showtip(this,event,'CDK7 strongly-dependent group 2 enhancer GRCh37_chr4:860125-861324')" onMouseOut="hidetip()" coords="157,35,227,43" alt="Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr4:860125-861324" href="/gene/126806940" />
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC105374341')" onMouseOut="hidetip()" coords="170,47,240,55" alt="Neighboring gene uncharacterized LOC105374341" href="/gene/105374341" />
<area shape="rect" onMouseOver="showtip(this,event,'CDK7 strongly-dependent group 2 enhancer GRCh37_chr4:872957-874156')" onMouseOut="hidetip()" coords="181,71,251,79" alt="Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr4:872957-874156" href="/gene/126806941" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr4:880593-881094')" onMouseOut="hidetip()" coords="196,59,266,67" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:880593-881094" href="/gene/127399722" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr4:881095-881594')" onMouseOut="hidetip()" coords="197,83,267,91" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:881095-881594" href="/gene/127399723" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr4:905677-906582')" onMouseOut="hidetip()" coords="244,35,314,43" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:905677-906582" href="/gene/127399724" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:906583-907488')" onMouseOut="hidetip()" coords="245,47,315,55" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:906583-907488" href="/gene/127399725" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 15112')" onMouseOut="hidetip()" coords="250,95,320,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15112" href="/gene/129991963" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 21139')" onMouseOut="hidetip()" coords="262,71,332,79" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21139" href="/gene/129991964" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 15113')" onMouseOut="hidetip()" coords="282,59,352,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15113" href="/gene/129991965" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 21140')" onMouseOut="hidetip()" coords="283,83,353,91" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21140" href="/gene/129991966" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr4:938924-939517')" onMouseOut="hidetip()" coords="307,107,377,115" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:938924-939517" href="/gene/127399726" />
<area shape="rect" onMouseOver="showtip(this,event,'transmembrane protein 175')" onMouseOut="hidetip()" coords="308,119,395,127" alt="Neighboring gene transmembrane protein 175" href="/gene/84286" />
<area shape="rect" onMouseOver="showtip(this,event,'ReSE screen-validated silencer GRCh37_chr4:957241-957400')" onMouseOut="hidetip()" coords="342,35,412,43" alt="Neighboring gene ReSE screen-validated silencer GRCh37_chr4:957241-957400" href="/gene/129661206" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:961731-962444')" onMouseOut="hidetip()" coords="350,23,420,31" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:961731-962444" href="/gene/127399727" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:962445-963158')" onMouseOut="hidetip()" coords="352,47,422,55" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:962445-963158" href="/gene/127399728" />
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC124900645')" onMouseOut="hidetip()" coords="352,71,422,79" alt="Neighboring gene uncharacterized LOC124900645" href="/gene/124900645" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr4:963506-964024')" onMouseOut="hidetip()" coords="353,59,423,67" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:963506-964024" href="/gene/127399729" />
<area shape="rect" onMouseOver="showtip(this,event,'diacylglycerol kinase theta')" onMouseOut="hidetip()" coords="373,83,423,91" alt="Neighboring gene diacylglycerol kinase theta" href="/gene/1609" />
</map>
</p>
</div>
</div>
<div class="rprt-section gene-genomic-regions-transcripts-products">
<section class="rprt-section-header" id="genomic-regions-transcripts-products">
<h2 id="header-genomic-regions-transcripts-products">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-regions-transcripts-products .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Genomic regions, transcripts, and products</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Genomic_Regions_Transcripts_a" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div>
<div style="text-align:right;">Go to <a href="#reference-sequences">reference sequence details</a></div>
</div>
<div>
<p class="choose">
<label for="accession" class="label">Genomic Sequence: </label>
<select name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.accessionList" sid="1" id="accessionList" data-taxid="9606" data-geneid="2580">
<option value="NC_000004.12_849276_932315">NC_000004.12 Chromosome 4 Reference GRCh38.p14 Primary Assembly</option>
<option value="NC_060928.1_847029_930387">NC_060928.1 Chromosome 4 Alternate T2T-CHM13v2.0</option>
<option value="NC_000004.11_843064_926103">NC_000004.11 Chromosome 4 Reference GRCh37.p13 Primary Assembly</option>
</select>
</p>
</div>
<div id="NC_000004" class="divAccession">
<div class="seq-viewer">
<p class="note-link">
<strong>Go to nucleotide:</strong>
<a title="Nucleotide Graphic report" href="/nuccore/NC_000004.12?report=graph&amp;from=836820&amp;to=944771&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=NC_000004.12">Graphics</a>
<a title="Nucleotide FASTA report" href="/nuccore/NC_000004.12?report=fasta&amp;from=849277&amp;to=932316&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=NC_000004.12">FASTA</a>
<a title="Nucleotide GenBank report" href="/nuccore/NC_000004.12?report=genbank&amp;from=849277&amp;to=932316&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=NC_000004.12">GenBank</a>
</p>
<div id="divNC_000004" class="SeqViewerApp" style="clear:both;" data-sv="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000004.12&amp;from=836820&amp;to=944771&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.40">
<a href="?appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000004.12&amp;from=836820&amp;to=944771&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.40"></a>
</div>
</div>
</div>
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000004.12" sid="1" type="hidden" id="nucleotideLink_NC_000004_12_849276_932315" value="&lt;p class=&quot;note-link&quot;&gt;&lt;strong&gt;Go to nucleotide:&lt;/strong&gt;&lt;a title=&quot;Nucleotide Graphic report&quot; href=&quot;/nuccore/NC_000004.12?report=graph&amp;amp;from=836820&amp;amp;to=944771&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.40&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=2580&amp;amp;link_uid=NC_000004.12&quot;&gt;Graphics&lt;/a&gt;&lt;a title=&quot;Nucleotide FASTA report&quot; href=&quot;/nuccore/NC_000004.12?report=fasta&amp;amp;from=849277&amp;amp;to=932316&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=2580&amp;amp;link_uid=NC_000004.12&quot;&gt;FASTA&lt;/a&gt;&lt;a title=&quot;Nucleotide GenBank report&quot; href=&quot;/nuccore/NC_000004.12?report=genbank&amp;amp;from=849277&amp;amp;to=932316&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=2580&amp;amp;link_uid=NC_000004.12&quot;&gt;GenBank&lt;/a&gt;&lt;/p&gt;" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000004.12" sid="1" type="hidden" id="relString_NC_000004_12_849276_932315" value="appname=ncbigene&amp;amp;embedded=true&amp;amp;noslider=1&amp;amp;id=NC_000004.12&amp;amp;from=836820&amp;amp;to=944771&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.40" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_060928.1" sid="1" type="hidden" id="nucleotideLink_NC_060928_1_847029_930387" value="&lt;p class=&quot;note-link&quot;&gt;&lt;strong&gt;Go to nucleotide:&lt;/strong&gt;&lt;a title=&quot;Nucleotide Graphic report&quot; href=&quot;/nuccore/NC_060928.1?report=graph&amp;amp;from=834525&amp;amp;to=942891&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_009914755.1&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=2580&amp;amp;link_uid=NC_060928.1&quot;&gt;Graphics&lt;/a&gt;&lt;a title=&quot;Nucleotide FASTA report&quot; href=&quot;/nuccore/NC_060928.1?report=fasta&amp;amp;from=847030&amp;amp;to=930388&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=2580&amp;amp;link_uid=NC_060928.1&quot;&gt;FASTA&lt;/a&gt;&lt;a title=&quot;Nucleotide GenBank report&quot; href=&quot;/nuccore/NC_060928.1?report=genbank&amp;amp;from=847030&amp;amp;to=930388&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=2580&amp;amp;link_uid=NC_060928.1&quot;&gt;GenBank&lt;/a&gt;&lt;/p&gt;" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_060928.1" sid="1" type="hidden" id="relString_NC_060928_1_847029_930387" value="appname=ncbigene&amp;amp;embedded=true&amp;amp;noslider=1&amp;amp;id=NC_060928.1&amp;amp;from=834525&amp;amp;to=942891&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_009914755.1" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000004.11" sid="1" type="hidden" id="nucleotideLink_NC_000004_11_843064_926103" value="&lt;p class=&quot;note-link&quot;&gt;&lt;strong&gt;Go to nucleotide:&lt;/strong&gt;&lt;a title=&quot;Nucleotide Graphic report&quot; href=&quot;/nuccore/NC_000004.11?report=graph&amp;amp;from=830608&amp;amp;to=938559&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.25&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=2580&amp;amp;link_uid=NC_000004.11&quot;&gt;Graphics&lt;/a&gt;&lt;a title=&quot;Nucleotide FASTA report&quot; href=&quot;/nuccore/NC_000004.11?report=fasta&amp;amp;from=843065&amp;amp;to=926104&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=2580&amp;amp;link_uid=NC_000004.11&quot;&gt;FASTA&lt;/a&gt;&lt;a title=&quot;Nucleotide GenBank report&quot; href=&quot;/nuccore/NC_000004.11?report=genbank&amp;amp;from=843065&amp;amp;to=926104&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=2580&amp;amp;link_uid=NC_000004.11&quot;&gt;GenBank&lt;/a&gt;&lt;/p&gt;" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000004.11" sid="1" type="hidden" id="relString_NC_000004_11_843064_926103" value="appname=ncbigene&amp;amp;embedded=true&amp;amp;noslider=1&amp;amp;id=NC_000004.11&amp;amp;from=830608&amp;amp;to=938559&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.25" />
</div>
</div>
<div class="rprt-section gene-gene-expression">
<section class="rprt-section-header" id="gene-expression">
<h2 id="header-gene-expression">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-gene-expression .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Expression</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Expression" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div>
<div style="text-align:right;">
<a href="/gene/2580/?report=expression" data-url="/gene/2580/?report=expression" id="gene-expression-see-details">See details</a>
</div>
<div id="gene-expression-app" data-url="https://www.ncbi.nlm.nih.gov/gene/2580" data-report-type="summary">
<div>
<script type="text/javascript">
window.tissues_data = {'adrenal 10wk': {'id': '2580_Adrenal_10wk_PRJNA270632', 'gene': 2580, 'source_name': 'adrenal 10wk', 'full_rpkm': 1.12397, 'exp_rpkm': 1.12, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263902}, 'adrenal 16wk': {'id': '2580_Adrenal_16wk_PRJNA270632', 'gene': 2580, 'source_name': 'adrenal 16wk', 'full_rpkm': 4.95684, 'exp_rpkm': 4.96, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263903}, 'adrenal 18wk': {'id': '2580_Adrenal_18wk_PRJNA270632', 'gene': 2580, 'source_name': 'adrenal 18wk', 'full_rpkm': 4.70586, 'exp_rpkm': 4.71, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263904}, 'adrenal 20wk': {'id': '2580_Adrenal_20wk_PRJNA270632', 'gene': 2580, 'source_name': 'adrenal 20wk', 'full_rpkm': 5.01495, 'exp_rpkm': 5.01, 'var': 1.610002, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263905}, 'heart 10wk': {'id': '2580_Heart_10wk;_PRJNA270632', 'gene': 2580, 'source_name': 'heart 10wk', 'full_rpkm': 1.56312, 'exp_rpkm': 1.56, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263906}, 'heart 11wk': {'id': '2580_Heart_11wk;_PRJNA270632', 'gene': 2580, 'source_name': 'heart 11wk', 'full_rpkm': 1.18679, 'exp_rpkm': 1.19, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263907}, 'heart 17wk': {'id': '2580_Heart_17wk;_PRJNA270632', 'gene': 2580, 'source_name': 'heart 17wk', 'full_rpkm': 0.654021, 'exp_rpkm': 0.654, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263908}, 'heart 18wk': {'id': '2580_Heart_18wk;_PRJNA270632', 'gene': 2580, 'source_name': 'heart 18wk', 'full_rpkm': 1.01403, 'exp_rpkm': 1.01, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263909}, 'heart 20wk': {'id': '2580_Heart_20wk_PRJNA270632', 'gene': 2580, 'source_name': 'heart 20wk', 'full_rpkm': 0.293579, 'exp_rpkm': 0.294, 'var': 0.01827279, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263910}, 'intestine 10wk': {'id': '2580_Intestine_10wk_PRJNA270632', 'gene': 2580, 'source_name': 'intestine 10wk', 'full_rpkm': 0.53694, 'exp_rpkm': 0.537, 'var': 0.00023582, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263911}, 'intestine 11wk': {'id': '2580_Intestine_11wk_PRJNA270632', 'gene': 2580, 'source_name': 'intestine 11wk', 'full_rpkm': 1.25805, 'exp_rpkm': 1.26, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263912}, 'intestine 15wk': {'id': '2580_Intestine_15wk_PRJNA270632', 'gene': 2580, 'source_name': 'intestine 15wk', 'full_rpkm': 1.6169, 'exp_rpkm': 1.62, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263913}, 'intestine 17wk': {'id': '2580_Intestine_17wk_PRJNA270632', 'gene': 2580, 'source_name': 'intestine 17wk', 'full_rpkm': 0.82189, 'exp_rpkm': 0.822, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263914}, 'intestine 20wk': {'id': '2580_Intestine_20wk_PRJNA270632', 'gene': 2580, 'source_name': 'intestine 20wk', 'full_rpkm': 2.10068, 'exp_rpkm': 2.1, 'var': 0.190911, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263915}, 'kidney 10wk': {'id': '2580_Kidney_10wk_PRJNA270632', 'gene': 2580, 'source_name': 'kidney 10wk', 'full_rpkm': 1.39264, 'exp_rpkm': 1.39, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263916}, 'kidney 16wk': {'id': '2580_Kidney_16wk_PRJNA270632', 'gene': 2580, 'source_name': 'kidney 16wk', 'full_rpkm': 0.741681, 'exp_rpkm': 0.742, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263917}, 'kidney 20wk': {'id': '2580_Kidney_20wk_PRJNA270632', 'gene': 2580, 'source_name': 'kidney 20wk', 'full_rpkm': 0.326283, 'exp_rpkm': 0.326, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263918}, 'lung 10wk': {'id': '2580_Lung_10wk_PRJNA270632', 'gene': 2580, 'source_name': 'lung 10wk', 'full_rpkm': 1.44685, 'exp_rpkm': 1.45, 'var': 0.000654542, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263919}, 'lung 17wk': {'id': '2580_Lung_17wk_PRJNA270632', 'gene': 2580, 'source_name': 'lung 17wk', 'full_rpkm': 1.35522, 'exp_rpkm': 1.36, 'var': 0.00686092, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263920}, 'lung 20wk': {'id': '2580_Lung_20wk_PRJNA270632', 'gene': 2580, 'source_name': 'lung 20wk', 'full_rpkm': 1.21658, 'exp_rpkm': 1.22, 'var': 0.0026606, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263921}, 'stomach 10wk': {'id': '2580_Stomach_10wk_PRJNA270632', 'gene': 2580, 'source_name': 'stomach 10wk', 'full_rpkm': 1.30193, 'exp_rpkm': 1.3, 'var': 0.1156562, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263922}, 'stomach 16wk': {'id': '2580_Stomach_16wk_PRJNA270632', 'gene': 2580, 'source_name': 'stomach 16wk', 'full_rpkm': 1.63377, 'exp_rpkm': 1.63, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734393597263923}, 'stomach 18wk': {'id': '2580_Stomach_18wk_PRJNA270632', 'gene': 2580, 'source_name': 'stomach 18wk', 'full_rpkm': 2.17421, 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<div>
<select name="p" id="project-selector">
<option value="SRP051249" selected="selected" data-bioproject="PRJNA270632">
Tissue-specific circular RNA induction during human fetal development
</option>
<option value="SRP056969" data-bioproject="PRJNA280600">
RNA sequencing of total RNA from 20 human tissues
</option>
<option value="ERP003613" data-bioproject="PRJEB4337">
HPA RNA-seq normal tissues
</option>
</select>
<ul id="project-summary">
<li id="project-summary-title">Project title:
Tissue-specific circular RNA induction during human fetal development
</li>
<li id="project-summary-desc">Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA</li>
<li id="project-summary-bioprojects">BioProject: <a href="/bioproject/PRJNA270632/">PRJNA270632</a>
</li>
<li id="project-summary-pubs">Publication:
<span><a href="/pubmed/26076956/">PMID 26076956</a></span>
</li>
<li id="project-summary-analysis-date">Analysis date: Mon Apr 2 22:54:59 2018</li>
</ul>
<div id="gene-expr-details" class="expression-chart"></div>
</div>
</div>
</div>
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<a href="#" class="jig-ncbitoggler-open">Related articles in PubMed</a>
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<ol class="generef-link">
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<a href="/pubmed/24438162/" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=24438162">Structure of cyclin G-associated kinase (GAK) trapped in different conformations using nanobodies.</a>
<span class="pubmed-auth-date"> Chaikuad A, <em>et al</em>. Biochem J, 2014 Apr 1. PMID 24438162, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC3957475/" ref="ordinalpos=0&amp;ncbi_uid=2580&amp;link_uid=PMC3957475">Free PMC Article</a></span></span>
</li>
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<a href="/pubmed/31962345/" ref="ordinalpos=2&amp;ncbi_uid=2580&amp;link_uid=31962345">Dynamics of Auxilin 1 and GAK in clathrin-mediated traffic.</a>
<span class="pubmed-auth-date"> He K, <em>et al</em>. J Cell Biol, 2020 Mar 2. PMID 31962345, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC7054993/" ref="ordinalpos=0&amp;ncbi_uid=2580&amp;link_uid=PMC7054993">Free PMC Article</a></span></span>
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<a href="/pubmed/20881269/" ref="ordinalpos=3&amp;ncbi_uid=2580&amp;link_uid=20881269">Cyclin G-associated kinase is necessary for osteosarcoma cell proliferation and receptor trafficking.</a>
<span class="pubmed-auth-date"> Susa M, <em>et al</em>. Mol Cancer Ther, 2010 Dec. PMID 20881269</span>
</li>
<li>
<a href="/pubmed/21258085/" ref="ordinalpos=4&amp;ncbi_uid=2580&amp;link_uid=21258085">Cyclin-G-associated kinase modifies α-synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study.</a>
<span class="pubmed-auth-date"> Dumitriu A, <em>et al</em>. Hum Mol Genet, 2011 Apr 15. PMID 21258085, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC3063983/" ref="ordinalpos=0&amp;ncbi_uid=2580&amp;link_uid=PMC3063983">Free PMC Article</a></span></span>
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<span class="pubmed-auth-date"> Li C, <em>et al</em>. Mov Disord, 2020 Nov. PMID 32662538</span>
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<p class="see-all-pm">
<a href="/pubmed?LinkName=gene_pubmed&amp;from_uid=2580" title="See all 116 citations in Pubmed">See all (116) citations in PubMed</a>
</p>
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</div>
<div class="generif-pubmed generif">
<h3 id="generifsgenereferencesintofunctions">
<a href="#" class="jig-ncbitoggler-open">GeneRIFs: Gene References Into Functions</a>
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<div>
<a href="/gene/about-generif" class="whatisthis">What's a GeneRIF?</a>
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<div id="gene-popper4" class="gene-rif-popper">Title: Dynamics of Auxilin 1 and GAK in clathrin-mediated traffic.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/28472763" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=28472763">These findings indicate that the abnormal mitoses seen after silencing OIP5-AS1 were caused by an untimely rise in GAK levels and suggest that OIP5-AS1 suppresses cell proliferation at least in part by reducing GAK levels.</a>
<div id="gene-popper5" class="gene-rif-popper">Title: LncRNA OIP5-AS1/cyrano suppresses GAK expression to control mitosis.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/26676575" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=26676575">that the multiple single nucleotide polymorphisms of GAK synergistically participate in the pathogenesis of sporadic Parkinson's disease through multiple pathways.</a>
<div id="gene-popper6" class="gene-rif-popper">Title: The Potential Mutation of GAK Gene in the Typical Sporadic Parkinson's Disease from the Han Population of Chinese Mainland.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/28829765" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=28829765">We have demonstrated that siRNA-mediated GAK silencing causes marked cell cycle disruption resulting in a raised sub-G1 alongside decreased G1 and G2/M cell cycle phases. Dual FBXW7-GAK inhibition increases multipolar mitoses</a>
<div id="gene-popper7" class="gene-rif-popper">Title: RNAi screen reveals synthetic lethality between cyclin G-associated kinase and FBXW7 by inducing aberrant mitoses.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/27508417" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=27508417">GAK gene expression is increased in Parkinson disease</a>
<div id="gene-popper8" class="gene-rif-popper">Title: The 4p16.3 Parkinson Disease Risk Locus Is Associated with GAK Expression and Genes Involved with the Synaptic Vesicle Membrane.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/28135906" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=28135906">These results suggest that the c-Src_GAK_MCM axis plays an important role in cell cycle progression through control of the DNA replication licensing system.</a>
<div id="gene-popper9" class="gene-rif-popper">Title: GAK is phosphorylated by c-Src and translocated from the centrosome to chromatin at the end of telophase.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/26318431" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=26318431">We filtered four OSCC genes including SERPINB9, SERPINE2, GAK, and HSP90B1 through the gene global prioritization score (P &lt; 0.005).</a>
<div id="gene-popper10" class="gene-rif-popper">Title: Genome-wide haplotype association analysis identifies SERPINB9, SERPINE2, GAK, and HSP90B1 as novel risk genes for oral squamous cell carcinoma.</div>
</li>
</ol>
</div>
<div class="submit-genrif">
<span>Submit:</span>
<a href="/gene/submit-generif/?geneId=2580&amp;sym=GAK&amp;name=cyclin G associated kinase&amp;org=Homo sapiens">New GeneRIF</a>
<a href="/RefSeq/update.cgi?geneid=2580&amp;symbol=GAK;task=fixpub">Correction</a>
<a href="https://www.ncbi.nlm.nih.gov/gene?db=gene&amp;report=generif&amp;term=2580" class="seeall-generif">See all GeneRIFs (33)</a>
</div>
</div>
</div>
</div>
</div>
<div class="rprt-section gene-phenotypes">
<section class="rprt-section-header" id="phenotypes">
<h2 id="header-phenotypes">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-phenotypes .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Phenotypes</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Phenotype" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body info-phenotype">
<p class="nochild-link">
<a href="/gtr/tests/?term=GAK[gene]">Find tests for this gene in the NIH Genetic Testing Registry (GTR)</a>
</p>
<p class="nochild-link">
<a href="/gap/PheGenI?tab=1&amp;gene=2580">Review eQTL and phenotype association data in this region using PheGenI</a>
</p>
<div>
<h3 id="ebigwascatalog">EBI GWAS Catalog</h3>
<table class="jig-ncbigrid gtr-associated-cond" data-jigconfig="isPageable: true, pageSize: 10">
<thead>
<tr>
<th class="description">Description</th>
</tr>
</thead>
<tbody>
<tr>
<td>Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/20711177">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/20711177">PubMed</a></span></div></div></div></td>
</tr>
<tr>
<td>Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/22438815">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/22438815">PubMed</a></span></div></div></div></td>
</tr>
<tr>
<td>Genomewide association study for susceptibility genes contributing to familial Parkinson disease.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/18985386">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/18985386">PubMed</a></span></div></div></div></td>
</tr>
<tr>
<td>Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/21292315">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/21292315">PubMed</a></span></div></div></div></td>
</tr>
<tr>
<td>Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/25064009">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/25064009">PubMed</a></span></div></div></div></td>
</tr>
<tr>
<td>Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/21738487">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/21738487">PubMed</a></span></div></div></div></td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
<div class="rprt-section gene-variation">
<section class="rprt-section-header" id="variation">
<h2 id="header-variation">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-variation .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Variation</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.variation" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<p class="nochild-link">
<a href="/clinvar/?term=GAK[gene]" ref="log$=recordlinks">See variants in ClinVar</a>
</p>
<p class="nochild-link">
<a href="/dbvar?LinkName=gene_dbvar&amp;from_uid=2580" ref="log$=recordlinks">See studies and variants in dbVar</a>
</p>
<p class="nochild-link">
<a href="/variation/view/?q=2580[geneid]&amp;assm=GCF_000001405.25" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh37.p13)">See Variation Viewer (GRCh37.p13)</a>
</p>
<p class="nochild-link">
<a href="/variation/view/?q=2580[geneid]" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh38)">See Variation Viewer (GRCh38)</a>
</p>
<set></set>
<set></set>
</div>
</div>
<div class="rprt-section gene-HIV-1-interactions">
<section class="rprt-section-header" id="HIV-1-interactions">
<h2 id="header-HIV-1-interactions">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-HIV-1-interactions .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">HIV-1 interactions</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.HIV1_interactions" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div class="fgrid">
<h3 id="proteininteractions">Protein interactions</h3>
<table summary="protein interactions" class="jig-ncbigrid">
<thead>
<tr>
<th id="hivprotein">Protein</th>
<th id="gene-hivprotein">Gene</th>
<th id="hivinter">Interaction</th>
<th id="hivpub">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="hivprotein">
<a href="/protein/25121906">retropepsin</a>
</td>
<td headers="gene-hivprotein">
<a href="/gene/155348">gag-pol</a>
</td>
<td headers="hivinter">HIV-1 PR is identified to have a physical interaction with cyclin G associated kinase (GAK) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses</td>
<td headers="hivpub">
<a title="PubMed Id(s): 22190034" href="/pubmed/22190034">PubMed</a>
</td>
</tr>
</tbody>
</table>
<p class="withnote">
<a class="note" href="/genome/viruses/retroviruses/hiv-1/interactions/">Go to the HIV-1, Human Interaction Database </a>
</p>
</div>
</div>
</div>
<div class="rprt-section gene-interactions">
<section class="rprt-section-header" id="interactions">
<h2 id="header-interactions">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-interactions .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Interactions</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Interactions" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<table summary="Gene Interaction" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/2580/data/interaction/',webserviceParams: 'p$l=Ajax&amp;p$debugoutput=off', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
<thead>
<tr>
<th id="inter-prod">Products</th>
<th id="inter-interactant">Interactant</th>
<th id="inter-otherGene">Other Gene</th>
<th id="inter-compl">Complex</th>
<th id="inter-source">Source</th>
<th id="inter-pubs">Pubs</th>
<th id="inter-desc">Description</th>
</tr>
</thead>
<tbody></tbody>
</table>
</div>
</div>
<div class="rprt-section gene-general-gene-info">
<section class="rprt-section-header" id="general-gene-info">
<h2 id="header-general-gene-info">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-gene-info .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">General gene information</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.General_Gene_Information" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body" style="">
<div id="gene-markers">
<h3 id="markers">
<a class="jig-ncbitoggler">Markers</a>
</h3>
<div>
<ul class="marker odd">
<li class="marker">NoName (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=483844%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=483844">UniSTS:483844</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">GAK__6772 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=466196%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=466196">UniSTS:466196</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">GDB:434012 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=157204%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=157204">UniSTS:157204</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">L17705 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=66091%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=66091">UniSTS:66091</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">sY3084 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=515126%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=515126">UniSTS:515126</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">NoName (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=482675%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=482675">UniSTS:482675</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">SHGC-145680 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=174723%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=174723">UniSTS:174723</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">WI-20233 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=57018%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=57018">UniSTS:57018</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">SHGC-68043 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=53741%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=53741">UniSTS:53741</a></li></ul></li>
</ul>
</div>
</div>
<div></div>
<div class="infosec">
<h3 id="homology">
<a class="jig-ncbitoggler-open">Homology</a>
</h3>
<ul class="geneinfo-subsec">
<li>
<a href="/gene/2580/ortholog/" id="ncbi-ortholog-link">NCBI Orthologs</a>
</li>
<a href="https://www.orthodb.org/?ncbi=2580" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8178" target="_blank">
Orthologs from OrthoDB
</a>
</ul>
</div>
<!--<component id="Gene_InfoPathway"/>-->
<div class="infosec info-comment" id="info-comment">
<h3 id="CloneNames">
<a class="jig-ncbitoggler-open">Clone Names</a>
</h3>
<ul class="geneinfo-subsec">
<li>FLJ16629, FLJ40395, MGC99654 </li>
</ul>
</div>
<div class="gene-ontology infosec">
<h3 id="gene-ontology">
<a class="jig-ncbitoggler-open">
<span>Gene Ontology</span>
</a>
<a target="_blank" href="http://www.ebi.ac.uk/GOA" class="g-ontology-src" title="Provided by GOA">Provided by GOA</a>
</h3>
<div class="ontology-tables">
<div class="ui-ncbigrid-outer-div">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
<thead>
<tr>
<th class="col1">Function</th>
<th style="width:12%;">Evidence Code</th>
<th style="width:10%;">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0004676">enables 3-phosphoinositide-dependent protein kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-1-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0004679">enables AMP-activated protein kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-2-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005524">enables ATP binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-3-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0004677">enables DNA-dependent protein kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-4-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0072518">enables Rho-dependent protein serine/threonine kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-5-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0030276">enables clathrin binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-6-0" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0030332">enables cyclin binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-7-0" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0004694">enables eukaryotic translation initiation factor 2alpha kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-8-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-8-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0044024">enables histone H2AS1 kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-9-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-9-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0072371">enables histone H2AS121 kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-10-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-10-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:1990244">enables histone H2AT120 kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-11-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-11-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0035979">enables histone H2AXS139 kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-12-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-12-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0044025">enables histone H2BS14 kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-13-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-13-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0140823">enables histone H2BS36 kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-14-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-14-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0035175">enables histone H3S10 kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-15-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-15-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0044022">enables histone H3S28 kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-16-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-16-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0140855">enables histone H3S57 kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-17-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-17-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0035402">enables histone H3T11 kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-18-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-18-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0072354">enables histone H3T3 kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-19-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-19-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0140857">enables histone H3T45 kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-20-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-20-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0035403">enables histone H3T6 kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-21-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-21-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0044023">enables histone H4S1 kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-22-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-22-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005515">enables protein binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-23-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
<div id="evidence-code-23-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/22645275,24510904,24947832,28514442,29513927,29568061,33961781" target="_blank" title="PubMed ID 22645275,24510904,24947832,28514442,29513927,29568061,33961781" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=22645275,24510904,24947832,28514442,29513927,29568061,33961781">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0106310">enables protein serine kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-24-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-24-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0004674">enables protein serine/threonine kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-25-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-25-0" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/9299234" target="_blank" title="PubMed ID 9299234" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=9299234">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0051087">enables protein-folding chaperone binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-26-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-26-0" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/26345367" target="_blank" title="PubMed ID 26345367" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=26345367">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0004711">enables ribosomal protein S6 kinase activity</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-27-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-27-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
</tbody>
</table>
</div>
</div>
<div class="ui-ncbigrid-outer-div">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
<thead>
<tr>
<th class="col1">Process</th>
<th style="width:12%;">Evidence Code</th>
<th style="width:10%;">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0007030">involved_in Golgi organization</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-1-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/16155256,24510904" target="_blank" title="PubMed ID 16155256,24510904" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=16155256,24510904">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0090160">involved_in Golgi to lysosome transport</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-2-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/16155256" target="_blank" title="PubMed ID 16155256" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=16155256">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0051085">involved_in chaperone cofactor-dependent protein refolding</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-3-1" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/26345367" target="_blank" title="PubMed ID 26345367" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=26345367">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0006338">involved_in chromatin remodeling</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-4-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0048268">involved_in clathrin coat assembly</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-5-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/16155256" target="_blank" title="PubMed ID 16155256" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=16155256">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0072318">involved_in clathrin coat disassembly</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-6-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0072318">involved_in clathrin coat disassembly</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-7-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/16155256" target="_blank" title="PubMed ID 16155256" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=16155256">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0072583">involved_in clathrin-dependent endocytosis</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-8-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-8-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0072583">involved_in clathrin-dependent endocytosis</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-9-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-9-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/16155256,18489706" target="_blank" title="PubMed ID 16155256,18489706" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=16155256,18489706">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0007029">involved_in endoplasmic reticulum organization</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-10-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-10-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0046907">involved_in intracellular transport</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-11-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-11-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/18489706" target="_blank" title="PubMed ID 18489706" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=18489706">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0010977">involved_in negative regulation of neuron projection development</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-12-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-12-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/24510904" target="_blank" title="PubMed ID 24510904" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=24510904">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0034067">involved_in protein localization to Golgi apparatus</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-13-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-13-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/16155256" target="_blank" title="PubMed ID 16155256" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=16155256">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0072659">involved_in protein localization to plasma membrane</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-14-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-14-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/16155256" target="_blank" title="PubMed ID 16155256" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=16155256">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0006898">involved_in receptor-mediated endocytosis</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-15-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-15-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/16155256" target="_blank" title="PubMed ID 16155256" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=16155256">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:1905443">involved_in regulation of clathrin coat assembly</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-16-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
<div id="evidence-code-16-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/18489706" target="_blank" title="PubMed ID 18489706" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=18489706">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0016191">involved_in synaptic vesicle uncoating</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-17-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
<div id="evidence-code-17-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/20160091" target="_blank" title="PubMed ID 20160091" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=20160091">PubMed</a> </td>
</tr>
</tbody>
</table>
</div>
</div>
<div class="ui-ncbigrid-outer-div">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-config="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
<thead>
<tr>
<th class="col1">Component</th>
<th style="width:12%;">Evidence Code</th>
<th style="width:10%;">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005794">located_in Golgi apparatus</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-1-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/16155256" target="_blank" title="PubMed ID 16155256" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=16155256">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0030136">located_in clathrin-coated vesicle</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-2-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/31962345" target="_blank" title="PubMed ID 31962345" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=31962345">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005737">is_active_in cytoplasm</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-3-2" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005829">located_in cytosol</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-4-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005925">located_in focal adhesion</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-5-2" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0043231">is_active_in intracellular membrane-bounded organelle</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-6-2" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0043231">located_in intracellular membrane-bounded organelle</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-7-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0016020">located_in membrane</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-8-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> HDA</a>
<div id="evidence-code-8-2" class="ecode">
<br />
<a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a>
</div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/19946888" target="_blank" title="PubMed ID 19946888" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=19946888">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0048471">located_in perinuclear region of cytoplasm</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-9-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-9-2" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0098793">located_in presynapse</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-10-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-10-2" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0031982">is_active_in vesicle</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-11-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-11-2" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0031982">located_in vesicle</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-12-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-12-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/24510904" target="_blank" title="PubMed ID 24510904" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=24510904">PubMed</a> </td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
</div>
</div>
</div>
<div class="rprt-section gene-general-protein-info">
<section class="rprt-section-header" id="general-protein-info">
<h2 id="header-general-protein-info">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-protein-info .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">General protein information</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.General_Protein_Information" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<dl>
<dt>Preferred Names</dt>
<dd>cyclin-G-associated kinase</dd>
</dl>
<dl>
<dt>Names</dt>
<dd>auxilin-2</dd>
<dd>dnaJ homolog subfamily C member 26</dd>
</dl>
<dl>
<dt class="heading">NP_001305063.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">NP_005246.2</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_005272325.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_005272327.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_011511727.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_011511728.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_011511729.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_011511730.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_011511731.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_011511732.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_011511733.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_011511734.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_011511736.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_016863480.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_016863481.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_016863482.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_016863483.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305958.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305959.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305960.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305961.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305962.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305963.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305964.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305966.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305967.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305968.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305969.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305970.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305971.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305972.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305974.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305975.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305976.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305977.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305978.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305979.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305980.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305981.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305982.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305984.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305985.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305986.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305987.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305988.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305989.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305990.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_047305991.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205549.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205550.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205551.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205552.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205553.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205554.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205555.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205556.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205557.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205558.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205559.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205560.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205561.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205562.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205563.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205564.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205565.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205566.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205567.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205568.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205569.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205570.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205571.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205572.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205573.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205574.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205575.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205576.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205577.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205578.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205579.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205580.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205581.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205582.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205583.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205584.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205585.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205586.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205587.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205588.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205589.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205590.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205591.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205592.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
<dl>
<dt class="heading">XP_054205593.1</dt>
<dd>
<ul class="geneinfo-subsec">
<li>EC <a href="http://enzyme.expasy.org/EC/2.7.11.1">2.7.11.1</a></li>
</ul>
</dd>
</dl>
</div>
</div>
<div class="rprt-section gene-reference-sequences">
<section class="rprt-section-header" id="reference-sequences">
<h2 id="header-reference-sequences">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-reference-sequences .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">NCBI Reference Sequences (RefSeq)</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.NCBI_Reference_Sequences_RefS" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<p>
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<strong>Try the new <a href="/datasets/tables/genes/?table_type=transcripts&amp;ids=2580&amp;utm_source=gene&amp;utm_medium=referral&amp;utm_campaign=refseq" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report." data-ga-category="refseq" data-ga-action="click_datasets_link" data-ga-label="transcript_table">Transcript table</a></strong>
</p>
<h3 class="genomerefseqs gene_std_toggler" id="refseqset-independent">
<a class="jig-ncbitoggler-open">RefSeqs maintained independently of Annotated
Genomes</a>
</h3>
<div class="genomerefseqs_slave">
<p class="desc"> These reference sequences exist independently of genome builds. <a href="#refseq-expl" id="expl-refseg">Explain</a></p>
<p id="refseq-expl"> These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in <a href="#geneGenomic regions, transcripts, and products">Genomic regions,
transcripts, and products</a> above. </p>
<h4 id="mrnaandproteins-p93761120">mRNA and Protein(s) </h4>
<ol>
<li>
<p><a href="/nuccore/NM_001318134.2">NM_001318134.2</a><a href="/protein/NP_001305063.1">NP_001305063.1</a>  cyclin-G-associated kinase isoform 3</p>
<p style="background:#fff; margin-top:1em;">Status: VALIDATED</p>
<dl>
<dt>Description</dt>
<dd>Transcript Variant: This variant (3) lacks three consecutive exons in the 5' coding region but maintains the same reading frame as variant 1. The encoded isoform (3) has the same N- and C-termini, but is shorter than isoform 1.</dd>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AA287110, AI138676, AK299554, BC000816, BC085005">AA287110, AI138676, AK299554, BC000816, BC085005</a>
</dd>
<dt>Consensus CDS</dt>
<dd>
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&amp;GO=MainBrowse&amp;DATA=CCDS82902.1">CCDS82902.1</a>
</dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000421361.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">ENSP00000421361.1</a>, <a href="http://www.ensembl.org/id/ENST00000511163.5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">ENST00000511163.5</a></dd>
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001305063.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99751">cd06257</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1181</span><span class="cddto">1225</span></dt>
<dd class="clearfix"> DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=214567">smart00220</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">53</span><span class="cddto">230</span></dt>
<dd class="clearfix"> S_TKc; Serine/Threonine protein kinases, catalytic domain</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=287393">pfam10409</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">491</span><span class="cddto">629</span></dt>
<dd class="clearfix"> PTEN_C2; C2 domain of PTEN tumour-suppressor protein</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=304357">cl21453</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">46</span><span class="cddto">241</span></dt>
<dd class="clearfix"> PKc_like; Protein Kinases, catalytic domain</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/NM_005255.4">NM_005255.4</a><a href="/protein/NP_005246.2">NP_005246.2</a>  cyclin-G-associated kinase isoform 1</p>
<p>
<a href="/ipg/NP_005246.2/" ref="ncbi_uid=2580">See identical proteins and their annotated locations for NP_005246.2</a>
</p>
<p style="background:#fff; margin-top:1em;">Status: VALIDATED</p>
<dl>
<dt>Description</dt>
<dd>Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).</dd>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AA287110, AI138676, BC000816, D88435, DA680073">AA287110, AI138676, BC000816, D88435, DA680073</a>
</dd>
<dt>Consensus CDS</dt>
<dd>
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&amp;GO=MainBrowse&amp;DATA=CCDS3340.1">CCDS3340.1</a>
</dd>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/O14976" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">O14976</a>, <a href="https://www.uniprot.org/uniprot/Q5U4P5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q5U4P5</a>, <a href="https://www.uniprot.org/uniprot/Q9BVY6" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q9BVY6</a></dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000314499.4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">ENSP00000314499.4</a>, <a href="http://www.ensembl.org/id/ENST00000314167.9" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">ENST00000314167.9</a></dd>
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_005246.2">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99751">cd06257</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1260</span><span class="cddto">1304</span></dt>
<dd class="clearfix"> DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=214567">smart00220</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">41</span><span class="cddto">309</span></dt>
<dd class="clearfix"> S_TKc; Serine/Threonine protein kinases, catalytic domain</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=270938">cd14036</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">39</span><span class="cddto">320</span></dt>
<dd class="clearfix"> STKc_GAK; Catalytic domain of the Serine/Threonine protein kinase, cyclin G-Associated Kinase</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=287393">pfam10409</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">570</span><span class="cddto">708</span></dt>
<dd class="clearfix"> PTEN_C2; C2 domain of PTEN tumour-suppressor protein</dd>
</dl>
</dd>
</dl>
</li>
</ol>
</div>
<h3 class="genomerefseqs gene_std_toggler" id="annotatedrefseq-title">
<a class="jig-ncbitoggler-open">RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08</a>
</h3>
<div class="genomerefseqs_slave">
<p class="desc"> The following sections contain reference sequences that belong to a
specific genome build. <a href="#" id="expl-genomes">Explain</a></p>
<p id="expl-genomes-desc" style="display:none">This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.</p>
<h3 id="refseq-sequencedescription-p33820512">Reference GRCh38.p14 Primary Assembly</h3>
<h4 id="genomic-p33820512">Genomic </h4>
<ol>
<li>
<p>NC_000004.12 Reference GRCh38.p14 Primary Assembly</p>
<dl>
<dt>Range</dt>
<dd class="rs-range">
<span>849277..932316 complement</span>
</dd>
<dt>Download</dt>
<dd><a href="/nuccore/NC_000004.12?from=849277&amp;to=932316&amp;report=genbank&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=NC_000004.12?from=849277&amp;to=932316&amp;report=genbank&amp;strand=true">GenBank</a>, <a href="/nuccore/NC_000004.12?from=849277&amp;to=932316&amp;report=fasta&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=NC_000004.12?from=849277&amp;to=932316&amp;report=fasta&amp;strand=true">FASTA</a>, <a href="/nuccore/NC_000004.12?from=836820&amp;to=944771&amp;report=graph&amp;content=5&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=NC_000004.12?from=836820&amp;to=944771&amp;report=graph&amp;content=5&amp;strand=true">Sequence Viewer (Graphics)</a></dd>
</dl>
</li>
</ol>
<h4 id="mrnaandproteins-p146527360">mRNA and Protein(s) </h4>
<ol>
<li>
<p><a href="/nuccore/XM_047450032.1">XM_047450032.1</a><a href="/protein/XP_047305988.1">XP_047305988.1</a>  cyclin-G-associated kinase isoform X41</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450022.1">XM_047450022.1</a><a href="/protein/XP_047305978.1">XP_047305978.1</a>  cyclin-G-associated kinase isoform X32</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450019.1">XM_047450019.1</a><a href="/protein/XP_047305975.1">XP_047305975.1</a>  cyclin-G-associated kinase isoform X28</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_017007992.2">XM_017007992.2</a><a href="/protein/XP_016863481.1">XP_016863481.1</a>  cyclin-G-associated kinase isoform X17</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450028.1">XM_047450028.1</a><a href="/protein/XP_047305984.1">XP_047305984.1</a>  cyclin-G-associated kinase isoform X37</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450024.1">XM_047450024.1</a><a href="/protein/XP_047305980.1">XP_047305980.1</a>  cyclin-G-associated kinase isoform X34</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450025.1">XM_047450025.1</a><a href="/protein/XP_047305981.1">XP_047305981.1</a>  cyclin-G-associated kinase isoform X35</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450031.1">XM_047450031.1</a><a href="/protein/XP_047305987.1">XP_047305987.1</a>  cyclin-G-associated kinase isoform X40</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450015.1">XM_047450015.1</a><a href="/protein/XP_047305971.1">XP_047305971.1</a>  cyclin-G-associated kinase isoform X24</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450004.1">XM_047450004.1</a><a href="/protein/XP_047305960.1">XP_047305960.1</a>  cyclin-G-associated kinase isoform X12</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450021.1">XM_047450021.1</a><a href="/protein/XP_047305977.1">XP_047305977.1</a>  cyclin-G-associated kinase isoform X31</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450029.1">XM_047450029.1</a><a href="/protein/XP_047305985.1">XP_047305985.1</a>  cyclin-G-associated kinase isoform X38</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_011513430.2">XM_011513430.2</a><a href="/protein/XP_011511732.1">XP_011511732.1</a>  cyclin-G-associated kinase isoform X8</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011511732.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99751">cd06257</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1225</span><span class="cddto">1269</span></dt>
<dd class="clearfix"> DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=214567">smart00220</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">53</span><span class="cddto">230</span></dt>
<dd class="clearfix"> S_TKc; Serine/Threonine protein kinases, catalytic domain</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=287393">pfam10409</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">491</span><span class="cddto">629</span></dt>
<dd class="clearfix"> PTEN_C2; C2 domain of PTEN tumour-suppressor protein</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=304357">cl21453</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">46</span><span class="cddto">241</span></dt>
<dd class="clearfix"> PKc_like; Protein Kinases, catalytic domain</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_011513434.3">XM_011513434.3</a><a href="/protein/XP_011511736.1">XP_011511736.1</a>  cyclin-G-associated kinase isoform X26</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011511736.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99751">cd06257</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1168</span><span class="cddto">1212</span></dt>
<dd class="clearfix"> DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=214567">smart00220</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1</span><span class="cddto">173</span></dt>
<dd class="clearfix"> S_TKc; Serine/Threonine protein kinases, catalytic domain</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=287393">pfam10409</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">434</span><span class="cddto">572</span></dt>
<dd class="clearfix"> PTEN_C2; C2 domain of PTEN tumour-suppressor protein</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=304357">cl21453</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1</span><span class="cddto">184</span></dt>
<dd class="clearfix"> PKc_like; Protein Kinases, catalytic domain</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450030.1">XM_047450030.1</a><a href="/protein/XP_047305986.1">XP_047305986.1</a>  cyclin-G-associated kinase isoform X39</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450012.1">XM_047450012.1</a><a href="/protein/XP_047305968.1">XP_047305968.1</a>  cyclin-G-associated kinase isoform X21</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450002.1">XM_047450002.1</a><a href="/protein/XP_047305958.1">XP_047305958.1</a>  cyclin-G-associated kinase isoform X10</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450010.1">XM_047450010.1</a><a href="/protein/XP_047305966.1">XP_047305966.1</a>  cyclin-G-associated kinase isoform X18</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_017007991.2">XM_017007991.2</a><a href="/protein/XP_016863480.1">XP_016863480.1</a>  cyclin-G-associated kinase isoform X7</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_011513427.3">XM_011513427.3</a><a href="/protein/XP_011511729.1">XP_011511729.1</a>  cyclin-G-associated kinase isoform X3</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011511729.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99751">cd06257</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1274</span><span class="cddto">1318</span></dt>
<dd class="clearfix"> DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=214567">smart00220</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">41</span><span class="cddto">279</span></dt>
<dd class="clearfix"> S_TKc; Serine/Threonine protein kinases, catalytic domain</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=287393">pfam10409</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">540</span><span class="cddto">678</span></dt>
<dd class="clearfix"> PTEN_C2; C2 domain of PTEN tumour-suppressor protein</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=304357">cl21453</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">39</span><span class="cddto">290</span></dt>
<dd class="clearfix"> PKc_like; Protein Kinases, catalytic domain</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450018.1">XM_047450018.1</a><a href="/protein/XP_047305974.1">XP_047305974.1</a>  cyclin-G-associated kinase isoform X27</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450026.1">XM_047450026.1</a><a href="/protein/XP_047305982.1">XP_047305982.1</a>  cyclin-G-associated kinase isoform X36</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450007.1">XM_047450007.1</a><a href="/protein/XP_047305963.1">XP_047305963.1</a>  cyclin-G-associated kinase isoform X15</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450014.1">XM_047450014.1</a><a href="/protein/XP_047305970.1">XP_047305970.1</a>  cyclin-G-associated kinase isoform X23</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450023.1">XM_047450023.1</a><a href="/protein/XP_047305979.1">XP_047305979.1</a>  cyclin-G-associated kinase isoform X33</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450005.1">XM_047450005.1</a><a href="/protein/XP_047305961.1">XP_047305961.1</a>  cyclin-G-associated kinase isoform X13</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_011513428.3">XM_011513428.3</a><a href="/protein/XP_011511730.1">XP_011511730.1</a>  cyclin-G-associated kinase isoform X4</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011511730.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99751">cd06257</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1255</span><span class="cddto">1299</span></dt>
<dd class="clearfix"> DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=214567">smart00220</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">41</span><span class="cddto">309</span></dt>
<dd class="clearfix"> S_TKc; Serine/Threonine protein kinases, catalytic domain</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=270938">cd14036</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">39</span><span class="cddto">320</span></dt>
<dd class="clearfix"> STKc_GAK; Catalytic domain of the Serine/Threonine protein kinase, cyclin G-Associated Kinase</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=287393">pfam10409</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">570</span><span class="cddto">708</span></dt>
<dd class="clearfix"> PTEN_C2; C2 domain of PTEN tumour-suppressor protein</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450006.1">XM_047450006.1</a><a href="/protein/XP_047305962.1">XP_047305962.1</a>  cyclin-G-associated kinase isoform X14</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450013.1">XM_047450013.1</a><a href="/protein/XP_047305969.1">XP_047305969.1</a>  cyclin-G-associated kinase isoform X22</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_005272268.3">XM_005272268.3</a><a href="/protein/XP_005272325.1">XP_005272325.1</a>  cyclin-G-associated kinase isoform X5</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_005272325.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99751">cd06257</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1249</span><span class="cddto">1293</span></dt>
<dd class="clearfix"> DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=214567">smart00220</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">41</span><span class="cddto">309</span></dt>
<dd class="clearfix"> S_TKc; Serine/Threonine protein kinases, catalytic domain</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=270938">cd14036</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">39</span><span class="cddto">320</span></dt>
<dd class="clearfix"> STKc_GAK; Catalytic domain of the Serine/Threonine protein kinase, cyclin G-Associated Kinase</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=287393">pfam10409</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">570</span><span class="cddto">708</span></dt>
<dd class="clearfix"> PTEN_C2; C2 domain of PTEN tumour-suppressor protein</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_011513426.3">XM_011513426.3</a><a href="/protein/XP_011511728.1">XP_011511728.1</a>  cyclin-G-associated kinase isoform X2</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011511728.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99751">cd06257</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1293</span><span class="cddto">1337</span></dt>
<dd class="clearfix"> DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=214567">smart00220</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">41</span><span class="cddto">309</span></dt>
<dd class="clearfix"> S_TKc; Serine/Threonine protein kinases, catalytic domain</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=270938">cd14036</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">39</span><span class="cddto">320</span></dt>
<dd class="clearfix"> STKc_GAK; Catalytic domain of the Serine/Threonine protein kinase, cyclin G-Associated Kinase</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=287393">pfam10409</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">570</span><span class="cddto">708</span></dt>
<dd class="clearfix"> PTEN_C2; C2 domain of PTEN tumour-suppressor protein</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_011513431.3">XM_011513431.3</a><a href="/protein/XP_011511733.1">XP_011511733.1</a>  cyclin-G-associated kinase isoform X9</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011511733.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99751">cd06257</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1221</span><span class="cddto">1265</span></dt>
<dd class="clearfix"> DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=214567">smart00220</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">41</span><span class="cddto">309</span></dt>
<dd class="clearfix"> S_TKc; Serine/Threonine protein kinases, catalytic domain</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=270938">cd14036</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">39</span><span class="cddto">320</span></dt>
<dd class="clearfix"> STKc_GAK; Catalytic domain of the Serine/Threonine protein kinase, cyclin G-Associated Kinase</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=287393">pfam10409</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">570</span><span class="cddto">708</span></dt>
<dd class="clearfix"> PTEN_C2; C2 domain of PTEN tumour-suppressor protein</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_005272270.3">XM_005272270.3</a><a href="/protein/XP_005272327.1">XP_005272327.1</a>  cyclin-G-associated kinase isoform X20</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_005272327.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99751">cd06257</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1185</span><span class="cddto">1229</span></dt>
<dd class="clearfix"> DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=214567">smart00220</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">41</span><span class="cddto">309</span></dt>
<dd class="clearfix"> S_TKc; Serine/Threonine protein kinases, catalytic domain</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=270938">cd14036</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">39</span><span class="cddto">320</span></dt>
<dd class="clearfix"> STKc_GAK; Catalytic domain of the Serine/Threonine protein kinase, cyclin G-Associated Kinase</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=287393">pfam10409</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">570</span><span class="cddto">708</span></dt>
<dd class="clearfix"> PTEN_C2; C2 domain of PTEN tumour-suppressor protein</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_011513425.3">XM_011513425.3</a><a href="/protein/XP_011511727.1">XP_011511727.1</a>  cyclin-G-associated kinase isoform X1</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011511727.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99751">cd06257</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1304</span><span class="cddto">1348</span></dt>
<dd class="clearfix"> DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=214567">smart00220</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">41</span><span class="cddto">309</span></dt>
<dd class="clearfix"> S_TKc; Serine/Threonine protein kinases, catalytic domain</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=270938">cd14036</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">39</span><span class="cddto">320</span></dt>
<dd class="clearfix"> STKc_GAK; Catalytic domain of the Serine/Threonine protein kinase, cyclin G-Associated Kinase</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=287393">pfam10409</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">570</span><span class="cddto">708</span></dt>
<dd class="clearfix"> PTEN_C2; C2 domain of PTEN tumour-suppressor protein</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_017007993.2">XM_017007993.2</a><a href="/protein/XP_016863482.1">XP_016863482.1</a>  cyclin-G-associated kinase isoform X26</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_016863482.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99751">cd06257</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1168</span><span class="cddto">1212</span></dt>
<dd class="clearfix"> DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=214567">smart00220</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1</span><span class="cddto">173</span></dt>
<dd class="clearfix"> S_TKc; Serine/Threonine protein kinases, catalytic domain</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=287393">pfam10409</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">434</span><span class="cddto">572</span></dt>
<dd class="clearfix"> PTEN_C2; C2 domain of PTEN tumour-suppressor protein</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=304357">cl21453</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1</span><span class="cddto">184</span></dt>
<dd class="clearfix"> PKc_like; Protein Kinases, catalytic domain</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_011513432.3">XM_011513432.3</a><a href="/protein/XP_011511734.1">XP_011511734.1</a>  cyclin-G-associated kinase isoform X11</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011511734.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99751">cd06257</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1216</span><span class="cddto">1260</span></dt>
<dd class="clearfix"> DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=214567">smart00220</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1</span><span class="cddto">221</span></dt>
<dd class="clearfix"> S_TKc; Serine/Threonine protein kinases, catalytic domain</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=287393">pfam10409</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">482</span><span class="cddto">620</span></dt>
<dd class="clearfix"> PTEN_C2; C2 domain of PTEN tumour-suppressor protein</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=304357">cl21453</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1</span><span class="cddto">232</span></dt>
<dd class="clearfix"> PKc_like; Protein Kinases, catalytic domain</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450020.1">XM_047450020.1</a><a href="/protein/XP_047305976.1">XP_047305976.1</a>  cyclin-G-associated kinase isoform X29</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450003.1">XM_047450003.1</a><a href="/protein/XP_047305959.1">XP_047305959.1</a>  cyclin-G-associated kinase isoform X11</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450016.1">XM_047450016.1</a><a href="/protein/XP_047305972.1">XP_047305972.1</a>  cyclin-G-associated kinase isoform X25</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_011513429.3">XM_011513429.3</a><a href="/protein/XP_011511731.1">XP_011511731.1</a>  cyclin-G-associated kinase isoform X6</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011511731.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99751">cd06257</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1242</span><span class="cddto">1286</span></dt>
<dd class="clearfix"> DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=214567">smart00220</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">24</span><span class="cddto">247</span></dt>
<dd class="clearfix"> S_TKc; Serine/Threonine protein kinases, catalytic domain</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=287393">pfam10409</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">508</span><span class="cddto">646</span></dt>
<dd class="clearfix"> PTEN_C2; C2 domain of PTEN tumour-suppressor protein</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=304357">cl21453</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">25</span><span class="cddto">258</span></dt>
<dd class="clearfix"> PKc_like; Protein Kinases, catalytic domain</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450011.1">XM_047450011.1</a><a href="/protein/XP_047305967.1">XP_047305967.1</a>  cyclin-G-associated kinase isoform X19</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450008.1">XM_047450008.1</a><a href="/protein/XP_047305964.1">XP_047305964.1</a>  cyclin-G-associated kinase isoform X16</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450034.1">XM_047450034.1</a><a href="/protein/XP_047305990.1">XP_047305990.1</a>  cyclin-G-associated kinase isoform X42</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450035.1">XM_047450035.1</a><a href="/protein/XP_047305991.1">XP_047305991.1</a>  cyclin-G-associated kinase isoform X43</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047450033.1">XM_047450033.1</a><a href="/protein/XP_047305989.1">XP_047305989.1</a>  cyclin-G-associated kinase isoform X42</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_017007994.2">XM_017007994.2</a><a href="/protein/XP_016863483.1">XP_016863483.1</a>  cyclin-G-associated kinase isoform X30</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
</ol>
<h3 id="refseq-sequencedescription-p94402752">Alternate T2T-CHM13v2.0</h3>
<h4 id="genomic-p94402752">Genomic </h4>
<ol>
<li>
<p>NC_060928.1 Alternate T2T-CHM13v2.0</p>
<dl>
<dt>Range</dt>
<dd class="rs-range">
<span>847030..930388 complement</span>
</dd>
<dt>Download</dt>
<dd><a href="/nuccore/NC_060928.1?from=847030&amp;to=930388&amp;report=genbank&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=NC_060928.1?from=847030&amp;to=930388&amp;report=genbank&amp;strand=true">GenBank</a>, <a href="/nuccore/NC_060928.1?from=847030&amp;to=930388&amp;report=fasta&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=NC_060928.1?from=847030&amp;to=930388&amp;report=fasta&amp;strand=true">FASTA</a>, <a href="/nuccore/NC_060928.1?from=834525&amp;to=942891&amp;report=graph&amp;content=5&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=NC_060928.1?from=834525&amp;to=942891&amp;report=graph&amp;content=5&amp;strand=true">Sequence Viewer (Graphics)</a></dd>
</dl>
</li>
</ol>
<h4 id="mrnaandproteins-p49069248">mRNA and Protein(s) </h4>
<ol>
<li>
<p><a href="/nuccore/XM_054349615.1">XM_054349615.1</a><a href="/protein/XP_054205590.1">XP_054205590.1</a>  cyclin-G-associated kinase isoform X41</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349606.1">XM_054349606.1</a><a href="/protein/XP_054205581.1">XP_054205581.1</a>  cyclin-G-associated kinase isoform X32</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349602.1">XM_054349602.1</a><a href="/protein/XP_054205577.1">XP_054205577.1</a>  cyclin-G-associated kinase isoform X28</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349590.1">XM_054349590.1</a><a href="/protein/XP_054205565.1">XP_054205565.1</a>  cyclin-G-associated kinase isoform X17</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349611.1">XM_054349611.1</a><a href="/protein/XP_054205586.1">XP_054205586.1</a>  cyclin-G-associated kinase isoform X37</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349608.1">XM_054349608.1</a><a href="/protein/XP_054205583.1">XP_054205583.1</a>  cyclin-G-associated kinase isoform X34</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349609.1">XM_054349609.1</a><a href="/protein/XP_054205584.1">XP_054205584.1</a>  cyclin-G-associated kinase isoform X35</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349614.1">XM_054349614.1</a><a href="/protein/XP_054205589.1">XP_054205589.1</a>  cyclin-G-associated kinase isoform X40</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349597.1">XM_054349597.1</a><a href="/protein/XP_054205572.1">XP_054205572.1</a>  cyclin-G-associated kinase isoform X24</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349585.1">XM_054349585.1</a><a href="/protein/XP_054205560.1">XP_054205560.1</a>  cyclin-G-associated kinase isoform X12</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349605.1">XM_054349605.1</a><a href="/protein/XP_054205580.1">XP_054205580.1</a>  cyclin-G-associated kinase isoform X31</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349612.1">XM_054349612.1</a><a href="/protein/XP_054205587.1">XP_054205587.1</a>  cyclin-G-associated kinase isoform X38</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349581.1">XM_054349581.1</a><a href="/protein/XP_054205556.1">XP_054205556.1</a>  cyclin-G-associated kinase isoform X8</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349600.1">XM_054349600.1</a><a href="/protein/XP_054205575.1">XP_054205575.1</a>  cyclin-G-associated kinase isoform X26</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349613.1">XM_054349613.1</a><a href="/protein/XP_054205588.1">XP_054205588.1</a>  cyclin-G-associated kinase isoform X39</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349594.1">XM_054349594.1</a><a href="/protein/XP_054205569.1">XP_054205569.1</a>  cyclin-G-associated kinase isoform X21</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349583.1">XM_054349583.1</a><a href="/protein/XP_054205558.1">XP_054205558.1</a>  cyclin-G-associated kinase isoform X10</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349591.1">XM_054349591.1</a><a href="/protein/XP_054205566.1">XP_054205566.1</a>  cyclin-G-associated kinase isoform X18</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349580.1">XM_054349580.1</a><a href="/protein/XP_054205555.1">XP_054205555.1</a>  cyclin-G-associated kinase isoform X7</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349576.1">XM_054349576.1</a><a href="/protein/XP_054205551.1">XP_054205551.1</a>  cyclin-G-associated kinase isoform X3</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349601.1">XM_054349601.1</a><a href="/protein/XP_054205576.1">XP_054205576.1</a>  cyclin-G-associated kinase isoform X27</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349610.1">XM_054349610.1</a><a href="/protein/XP_054205585.1">XP_054205585.1</a>  cyclin-G-associated kinase isoform X36</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349588.1">XM_054349588.1</a><a href="/protein/XP_054205563.1">XP_054205563.1</a>  cyclin-G-associated kinase isoform X15</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349596.1">XM_054349596.1</a><a href="/protein/XP_054205571.1">XP_054205571.1</a>  cyclin-G-associated kinase isoform X23</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349607.1">XM_054349607.1</a><a href="/protein/XP_054205582.1">XP_054205582.1</a>  cyclin-G-associated kinase isoform X33</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349586.1">XM_054349586.1</a><a href="/protein/XP_054205561.1">XP_054205561.1</a>  cyclin-G-associated kinase isoform X13</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349577.1">XM_054349577.1</a><a href="/protein/XP_054205552.1">XP_054205552.1</a>  cyclin-G-associated kinase isoform X4</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349587.1">XM_054349587.1</a><a href="/protein/XP_054205562.1">XP_054205562.1</a>  cyclin-G-associated kinase isoform X14</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349595.1">XM_054349595.1</a><a href="/protein/XP_054205570.1">XP_054205570.1</a>  cyclin-G-associated kinase isoform X22</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349578.1">XM_054349578.1</a><a href="/protein/XP_054205553.1">XP_054205553.1</a>  cyclin-G-associated kinase isoform X5</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349575.1">XM_054349575.1</a><a href="/protein/XP_054205550.1">XP_054205550.1</a>  cyclin-G-associated kinase isoform X2</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349582.1">XM_054349582.1</a><a href="/protein/XP_054205557.1">XP_054205557.1</a>  cyclin-G-associated kinase isoform X9</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349593.1">XM_054349593.1</a><a href="/protein/XP_054205568.1">XP_054205568.1</a>  cyclin-G-associated kinase isoform X20</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349574.1">XM_054349574.1</a><a href="/protein/XP_054205549.1">XP_054205549.1</a>  cyclin-G-associated kinase isoform X1</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349599.1">XM_054349599.1</a><a href="/protein/XP_054205574.1">XP_054205574.1</a>  cyclin-G-associated kinase isoform X26</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349584.1">XM_054349584.1</a><a href="/protein/XP_054205559.1">XP_054205559.1</a>  cyclin-G-associated kinase isoform X11</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349603.1">XM_054349603.1</a><a href="/protein/XP_054205578.1">XP_054205578.1</a>  cyclin-G-associated kinase isoform X29</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349598.1">XM_054349598.1</a><a href="/protein/XP_054205573.1">XP_054205573.1</a>  cyclin-G-associated kinase isoform X25</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349579.1">XM_054349579.1</a><a href="/protein/XP_054205554.1">XP_054205554.1</a>  cyclin-G-associated kinase isoform X6</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349592.1">XM_054349592.1</a><a href="/protein/XP_054205567.1">XP_054205567.1</a>  cyclin-G-associated kinase isoform X19</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349589.1">XM_054349589.1</a><a href="/protein/XP_054205564.1">XP_054205564.1</a>  cyclin-G-associated kinase isoform X16</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349617.1">XM_054349617.1</a><a href="/protein/XP_054205592.1">XP_054205592.1</a>  cyclin-G-associated kinase isoform X42</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349618.1">XM_054349618.1</a><a href="/protein/XP_054205593.1">XP_054205593.1</a>  cyclin-G-associated kinase isoform X43</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349616.1">XM_054349616.1</a><a href="/protein/XP_054205591.1">XP_054205591.1</a>  cyclin-G-associated kinase isoform X42</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/Q59HA5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">Q59HA5</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054349604.1">XM_054349604.1</a><a href="/protein/XP_054205579.1">XP_054205579.1</a>  cyclin-G-associated kinase isoform X30</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/B4DS37" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=2580&amp;nlmid=&amp;db=gene">B4DS37</a>
</dd>
</dl>
</li>
</ol>
</div>
<h3 class="genomerefseqs gene_std_toggler">
<a class="jig-ncbitoggler">Suppressed Reference Sequence(s)</a>
</h3>
<div class="genomerefseqs_slave">
<p class="desc"> The following Reference Sequences have been suppressed. <a href="#expl-suppressed-desc" id="expl-suppressed">Explain</a></p>
<p id="expl-suppressed-desc" style="display:none">These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.</p>
<ol>
<li>
<p><a href="/nuccore/558472757">NM_001286833.1</a>: Suppressed sequence</p>
<dl>
<dt>Description</dt>
<dd>NM_001286833.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.</dd>
</dl>
</li>
</ol>
</div>
</div>
</div>
<div class="rprt-section gene-related-sequences">
<section class="rprt-section-header" id="related-sequences">
<h2 id="header-related-sequences">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-related-sequences .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Related sequences</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Related_Sequences" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div>
<table id="proteinTblId" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/2580/data/related-sequences/',webserviceParams: 'p$l=Ajax', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
<thead>
<tr>
<th colspan="2" id="rs-nucleo">Nucleotide</th>
<th rowspan="2" id="rs-protein">Protein</th>
</tr>
<tr>
<th id="rs-heading">Heading</th>
<th id="rs-heading-acc">Accession and Version</th>
</tr>
</thead>
<tbody></tbody>
</table>
<table id="proteinTblId" class="jig-ncbigrid" data-jigconfig="isPageable:true, pageSize:25">
<thead>
<tr>
<th class="proteinTblTh" rowspan="2" id="rs-prot-acc">Protein Accession</th>
<th class="proteinTblTh" colspan="2" id="rs-link">Links</th>
</tr>
<tr>
<th id="rs-genepept">GenPept Link</th>
<th id="rs-uniprot">UniProtKB Link</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="rs-prot-acc">O14976.2</td>
<td headers="rs-link rs-genepept">
<a href="/protein/17375734" ref="ordinalpos=1&amp;ncbi_uid=2580&amp;link_uid=17375734">GenPept</a>
</td>
<td>
<a href="https://www.uniprot.org/uniprot/O14976">UniProtKB/Swiss-Prot:O14976</a>
</td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
<div class="rprt-section gene-additional-links">
<section class="rprt-section-header" id="additional-links"><h2 id="header-additional-links"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-additional-links .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Additional links</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Additional_Links" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
<div class="rprt-section-body" style="">
<h3 class="withnote" id="genelinkout">
<a class="jig-ncbitoggler">Gene LinkOut</a>
</h3><div>
<p>The following <a href="https://www.ncbi.nlm.nih.gov/projects/linkout/index.html">LinkOut</a> resources are supplied by external providers. These providers are responsible for maintaining the links. </p>
<div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Chemical Information</span>
</a>
<ul>
<li><span class="free-rsc"></span>Interologous Interaction Database</li>
<ul>
<li>
<a target="_blank" href="http://ophid.utoronto.ca/redirect/ncbi/human?proteins=2580" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7911">
<span>Interologous Interaction Database</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>MilliporeSigma</li>
<ul>
<li>
<a target="_blank" href="https://www.sigmaaldrich.com/catalog/genes/GAK?lang=en&amp;region=US" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9978">
<span>Gak products</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Molecular Biology Databases</span>
</a>
<ul>
<li><span class="free-rsc"></span>Bgee database</li>
<ul>
<li>
<a target="_blank" href="https://www.bgee.org/gene/ENSG00000178950" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10418">
<span>GAK gene expression</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>BioGPS</li>
<ul>
<li>
<a target="_blank" href="http://biogps.org/gene/2580/" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5059">
<span>BioGPS</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>BioGRID Open Repository of CRISPR Screens (ORCS)</li>
<ul>
<li>
<a target="_blank" href="https://orcs.thebiogrid.org/Gene/2580" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10164">
<span>BioGRID CRISPR Screen Phenotypes (478 hits/1417 screens)</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Eukaryotic Promoter Database</li>
<ul>
<li>
<a target="_blank" href="http://epd.vital-it.ch/cgi-bin/get_doc?db=hgEpdNew&amp;format=genome&amp;entry=GAK_1" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9624">
<span>GAK_1</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>GlyGen glycoinformatics resource</li>
<ul>
<li>
<a target="_blank" href="https://glygen.org/protein/O14976" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10227">
<span>GlyGen glycoinformatics resource</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Guide to Pharmacology</li>
<ul>
<li>
<a target="_blank" href="https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2027" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8191">
<span>cyclin G associated kinase gene</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Human eFP Browser</li>
<ul>
<li>
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Skeletal_Immune_Digestive&amp;modeInput=Absolute&amp;primaryGene=2580" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8875">
<span>Human eFP Browser</span>
</a>
</li>
<li>
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Circulatory_Respiratory&amp;modeInput=Absolute&amp;primaryGene=2580" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8875">
<span>Human eFP Browser</span>
</a>
</li>
<li>
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Nervous&amp;modeInput=Absolute&amp;primaryGene=2580" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8875">
<span>Human eFP Browser</span>
</a>
</li>
</ul>
<li>Ingenuity Pathways Analysis</li>
<ul>
<li>
<a target="_blank" href="http://partnersolution.ingenuity.com/?cid=97ae3f91eab87a&amp;p1=Entrez&amp;p2=GV&amp;s=&amp;ipaUri=%2Fpa%2Fapi%2Fv2%2Fgeneview%3Fapplicationname%3DEntrez%26geneId%3D2580%26geneidtype%3Dentrezgene" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5628">
<span>Ingenuity Pathways Analysis</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>InnateDB</li>
<ul>
<li>
<a target="_blank" href="http://www.innatedb.com/getGeneCard.do?id=6126" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7894">
<span>InnateDB</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>InterMine</li>
<ul>
<li>
<a target="_blank" href="https://www.humanmine.org/humanmine/search?keyword=ENSG00000178950" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9169">
<span>InterMine</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Kyoto Encyclopedia of Genes and Genomes</li>
<ul>
<li>
<a target="_blank" href="http://www.genome.jp/dbget-bin/www_bget?hsa:2580" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5174">
<span>Kyoto Encyclopedia of Genes and Genomes</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>OMA Browser: Orthologous MAtrix</li>
<ul>
<li>
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN74446/" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9822">
<span>OMA Browser: Orthologous MAtrix</span>
</a>
</li>
<li>
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN74445/" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9822">
<span>OMA Browser: Orthologous MAtrix</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>OrthoDB catalog of orthologs</li>
<ul>
<li>
<a target="_blank" href="https://www.orthodb.org/?ncbi=2580" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8178">
<span>Orthologs</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Pharmacogenomics Knowledge Base</li>
<ul>
<li>
<a target="_blank" href="https://www.pharmgkb.org/gene/PA28528" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=4067">
<span>Annotated Pharmacogenomic Information for GAK [PharmGKB]</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>PhosphoSitePlus</li>
<ul>
<li>
<a target="_blank" href="https://www.phosphosite.org/entrezGeneIdAction.action?id=2580" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7987">
<span>PhosphoSitePlus® - comprehensive post-translational modification resource</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>The Weizmann Institute of Science GeneCards and MalaCards databases</li>
<ul>
<li>
<a target="_blank" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=GAK" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8598">
<span>GeneCard for GAK</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Research Materials</span>
</a>
<ul>
<li><span class="order-rsc"></span>Addgene Non-profit plasmid repository</li>
<ul>
<li>
<a target="_blank" href="https://addgene.org//browse/gene/2580" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5304">
<span>Get Plasmids - Addgene</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>Bio-Techne</li>
<ul>
<li>
<a target="_blank" href="https://www.bio-techne.com/t/gak/antibodies?utm_source=linkout&amp;utm_medium=referral&amp;utm_campaign=product&amp;utm_term=antibodies" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8242">
<span>GAK Antibodies</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.bio-techne.com/t/gak/proteins-enzymes?utm_source=linkout&amp;utm_medium=referral&amp;utm_campaign=product&amp;utm_term=proteins" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8242">
<span>GAK Proteins</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.bio-techne.com/t/gak/lysates?utm_source=linkout&amp;utm_medium=referral&amp;utm_campaign=product&amp;utm_term=lysates" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8242">
<span>GAK Lysates</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>Creative Biogene</li>
<ul>
<li>
<a target="_blank" href="https://www.creative-biogene.com/genesearch/GAK.html" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10094">
<span>cyclin G associated kinase</span>
</a>
</li>
</ul>
<li>ExactAntigen/Labome</li>
<ul>
<li>
<a target="_blank" href="https://www.labome.com/review/gene/human/GAK-antibody.html" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5753">
<span>reagent review</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.labome.com/gene/human/GAK-antibody.html" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5753">
<span>reagents</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>GenScript latest version of gene cDNA ORF Clone</li>
<ul>
<li>
<a target="_blank" href="http://www.genscript.com/gene/2580" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8012">
<span>GenScript latest version of gene cDNA ORF Clone</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>GeneCopoeia Inc.</li>
<ul>
<li>
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=11&amp;field=5&amp;key=2580" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7255">
<span>Order shRNA clones</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=22&amp;field=5&amp;key=2580" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7255">
<span>Order promoter clone</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=1&amp;field=5&amp;key=2580" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7255">
<span>Order full-length ORF clone</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>Kazusa DNA Research Institute</li>
<ul>
<li>
<a target="_blank" href="http://www.kazusa.or.jp/kop/dsearch/symsearch.cgi?keyword=GAK;" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=3267">
<span>Kazusa DNA Research Institute</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>OriGene</li>
<ul>
<li>
<a target="_blank" href="https://www.origene.com/search?q=Gak" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7994">
<span>Order Gak cDNA clone/Protein/Antibody/RNAi</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Tools</span>
</a>
<ul>
<li><span class="free-rsc"></span>GeneMANIA</li>
<ul>
<li>
<a target="_blank" href="http://genemania.org/link?o=9606&amp;g=2580" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7529">
<span>GeneMANIA</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open">
<span>Miscellaneous</span>
</a>
<ul>
<li><span class="free-rsc"></span>Reactome</li>
<ul>
<li>
<a target="_blank" href="https://reactome.org/content/query?q=UniProt:O14976" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=4914">
<span>Reactome Entity:O14976</span>
</a>
</li>
<li>
<a target="_blank" href="https://reactome.org/PathwayBrowser/#/R-HSA-5653656" ref="itool=Gene_FullReport&amp;uid=2580&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=4914">
<span>Reactome Event:Vesicle-mediated transport</span>
</a>
</li>
</ul>
</ul>
</div>
</div>
</div>
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<h2 class="offscreen_noflow">Supplemental Content</h2>
<div id="gene-sidebar">
<div>
<div class="portlet brieflink dis-table-of-contents">
<div class="portlet_head">
<div class="portlet_title">
<h3>Table of contents</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_TableOfContents" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter"></a>
</div>
<div class="portlet_content">
<ul>
<li class="">
<a href="#summary">Summary</a>
</li>
<li class="">
<a href="#genomic-context">Genomic context</a>
</li>
<li class="">
<a href="#genomic-regions-transcripts-products">Genomic regions, transcripts, and products</a>
</li>
<li class="">
<a href="#gene-expression">Expression</a>
</li>
<li class="">
<a href="#bibliography">Bibliography</a>
</li>
<li class="">
<a href="#phenotypes">Phenotypes</a>
</li>
<li class="">
<a href="#variation">Variation</a>
</li>
<li class="">
<a href="#HIV-1-interactions">HIV-1 interactions</a>
</li>
<li class="">
<a href="#interactions">Interactions</a>
</li>
<li class="">
<a href="#general-gene-info">General gene information</a>
<div class="subsection-links"><a href="#gene-markers">Markers</a>, <a href="#CloneNames">Clone Names</a>, <a href="#homology">Homology</a>, <a href="#gene-ontology">Gene Ontology</a></div>
</li>
<li class="">
<a href="#general-protein-info">General protein information</a>
</li>
<li class="">
<a href="#reference-sequences">NCBI Reference Sequences (RefSeq)</a>
</li>
<li class="">
<a href="#related-sequences">Related sequences</a>
</li>
<li class="">
<a href="#additional-links">Additional links</a>
</li>
</ul>
</div>
</div>
<div class="portlet brieflink dis-genomesbrowser brieflink dis-genomesbrowser">
<div class="portlet_head">
<div class="portlet_title">
<h3>Genome Browsers</h3>
</div>
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<li>
<a href="#">Loading...</a>
</li>
</ul>
</div>
</div>
<div class="portlet dis-related-info brieflink">
<div class="portlet_head">
<div class="portlet_title">
<h3>Related information</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="discovery_db_links" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter"></a>
</div>
<div class="portlet_content DiscoveryDbLinks">
<ul>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/clone/order/gene/2580" ref="log$=recordlinks">Order cDNA clone</a>
<div class="brieflinkpop offscreen_noflow">Order cDNA clone</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/structure?LinkName=gene_structure&amp;from_uid=2580" ref="log$=recordlinks">3D structures</a>
<div class="brieflinkpop offscreen_noflow">3D structure of a gene</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_alltarget_list&amp;from_uid=2580" ref="log$=recordlinks">BioAssay by Target (List)</a>
<div class="brieflinkpop offscreen_noflow">BioAssays related to the gene by protein target or RNAi target</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="//pubchem.ncbi.nlm.nih.gov/assay/bioactivity.html?geneid=2580" ref="log$=recordlinks">BioAssay by Target (Summary)</a>
<div class="brieflinkpop offscreen_noflow">Summarized PubChem Data on the gene, showing the active data by default</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_target&amp;from_uid=2580" ref="log$=recordlinks">BioAssay, by Gene target</a>
<div class="brieflinkpop offscreen_noflow">PubChem BioAssays done on the Gene target</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_rnai&amp;from_uid=2580" ref="log$=recordlinks">BioAssays, RNAi Target, Tested</a>
<div class="brieflinkpop offscreen_noflow">BioAssays that contain the gene as the target of a RNAi reagent</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/bioproject?LinkName=gene_bioproject&amp;from_uid=2580" ref="log$=recordlinks">BioProjects</a>
<div class="brieflinkpop offscreen_noflow">BioProjects related to a gene</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/biosystems?LinkName=gene_biosystems&amp;from_uid=2580" ref="log$=recordlinks">BioSystems</a>
<div class="brieflinkpop offscreen_noflow">BioSystems</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/CCDS/CcdsBrowse.cgi?REQUEST=GENEID&amp;DATA=2580" ref="log$=recordlinks">CCDS</a>
<div class="brieflinkpop offscreen_noflow">Link to CCDS</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar&amp;from_uid=2580" ref="log$=recordlinks">ClinVar</a>
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/cdd?LinkName=gene_cdd&amp;from_uid=2580" ref="log$=recordlinks">Conserved Domains</a>
<div class="brieflinkpop offscreen_noflow">Related CDD</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/dbvar?LinkName=gene_dbvar&amp;from_uid=2580" ref="log$=recordlinks">dbVar</a>
<div class="brieflinkpop offscreen_noflow">Link from Gene to dbVar</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc&amp;from_uid=2580" ref="log$=recordlinks">Full text in PMC</a>
<div class="brieflinkpop offscreen_noflow">PMC links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc_nucleotide&amp;from_uid=2580" ref="log$=recordlinks">Full text in PMC_nucleotide</a>
<div class="brieflinkpop offscreen_noflow">Full text in PubMedCentral identified from shared sequence links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/sparcle?LinkName=gene_sparcle&amp;from_uid=2580" ref="log$=recordlinks">Functional Class</a>
<div class="brieflinkpop offscreen_noflow">Functional class of the sequence domain architecture</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_neighbors&amp;from_uid=2580" ref="log$=recordlinks">Gene neighbors</a>
<div class="brieflinkpop offscreen_noflow">Overlapping genes and two nearest non-overlapping genes on either side</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_h3k4me3&amp;from_uid=2580" ref="log$=recordlinks">Genes with a similar H3K4me3 profile</a>
<div class="brieflinkpop offscreen_noflow">Genes with a similar profile of promoter-activating H3K4me3 modifications across several tissue types</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/genome?LinkName=gene_genome&amp;from_uid=2580" ref="log$=recordlinks">Genome</a>
<div class="brieflinkpop offscreen_noflow">Related Genome</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/geoprofiles?LinkName=gene_geoprofiles&amp;from_uid=2580" ref="log$=recordlinks">GEO Profiles</a>
<div class="brieflinkpop offscreen_noflow">Related GEO</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gtr/tests/?term=2580[geneid]" ref="log$=recordlinks">GTR</a>
<div class="brieflinkpop offscreen_noflow">Tests for this gene in the NIH Genetic Testing Registry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/homologene?LinkName=gene_homologene&amp;from_uid=2580" ref="log$=recordlinks">HomoloGene</a>
<div class="brieflinkpop offscreen_noflow">Related HomoloGene</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore&amp;from_uid=2580" ref="log$=recordlinks">Nucleotide</a>
<div class="brieflinkpop offscreen_noflow">Link to related Nucleotide entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/omim?LinkName=gene_omim&amp;from_uid=2580" ref="log$=recordlinks">OMIM</a>
<div class="brieflinkpop offscreen_noflow">Link to related OMIM entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/probe?LinkName=gene_probe&amp;from_uid=2580" ref="log$=recordlinks">Probe</a>
<div class="brieflinkpop offscreen_noflow">Related Probe entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein&amp;from_uid=2580" ref="log$=recordlinks">Protein</a>
<div class="brieflinkpop offscreen_noflow">Link to related protein entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pccompound?LinkName=gene_pccompound&amp;from_uid=2580" ref="log$=recordlinks">PubChem Compound</a>
<div class="brieflinkpop offscreen_noflow">PubChem Compounds</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcsubstance?LinkName=gene_pcsubstance&amp;from_uid=2580" ref="log$=recordlinks">PubChem Substance</a>
<div class="brieflinkpop offscreen_noflow">PubChem Substances</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed&amp;from_uid=2580" ref="log$=recordlinks">PubMed</a>
<div class="brieflinkpop offscreen_noflow">Link to related PubMed entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_rif&amp;from_uid=2580" ref="log$=recordlinks">PubMed (GeneRIF)</a>
<div class="brieflinkpop offscreen_noflow">Link to related PubMed article from GeneRIFs</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_citedinomim&amp;from_uid=2580" ref="log$=recordlinks">PubMed (OMIM)</a>
<div class="brieflinkpop offscreen_noflow">Gene links to PubMed derived from omim_pubmed_cited links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_pmc_nucleotide&amp;from_uid=2580" ref="log$=recordlinks">PubMed(nucleotide/PMC)</a>
<div class="brieflinkpop offscreen_noflow">Citations in PubMed identified from shared sequence and PMC links.</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein_refseq&amp;from_uid=2580" ref="log$=recordlinks">RefSeq Proteins</a>
<div class="brieflinkpop offscreen_noflow">Link to Protein RefSeqs</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore_refseqrna&amp;from_uid=2580" ref="log$=recordlinks">RefSeq RNAs</a>
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeq RNAs</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar_specific&amp;from_uid=2580" ref="log$=recordlinks">Related gene-specific medical variations</a>
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/snp?LinkName=gene_snp&amp;from_uid=2580" ref="log$=recordlinks">SNP</a>
<div class="brieflinkpop offscreen_noflow">Related SNP records</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/taxonomy?LinkName=gene_taxonomy&amp;from_uid=2580" ref="log$=recordlinks">Taxonomy</a>
<div class="brieflinkpop offscreen_noflow">Link to related taxonomy entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/variation/view/?q=2580[geneid]" ref="log$=recordlinks">Variation Viewer</a>
<div class="brieflinkpop offscreen_noflow">Related Variants</div>
</li>
</ul>
</div>
</div>
<div class="portlet dis-links-to-other-res brieflink">
<div class="portlet_head">
<div class="portlet_title">
<h3>Links to other resources</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_LinksTwo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter"></a>
</div>
<div class="portlet_content">
<ul>
<li>
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:4113">HGNC</a>
</li>
<li>
<a href="http://www.ensembl.org/id/ENSG00000178950">Ensembl</a>
</li>
<li>
<a href="https://www.alliancegenome.org/gene/HGNC:4113">AllianceGenome</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=geneid&amp;org=9606&amp;l=2580">AceView</a>
</li>
<li>
<a href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&amp;position=NM_005255">UCSC</a>
</li>
<li>
<a href="https://genecollections.nci.nih.gov/MGC/?ORG=Hs&amp;LIST=BC085005">MGC</a>
</li>
<li>
<a href="https://phgkb.cdc.gov/PHGKB/huGEPedia.action?firstQuery=GAK&amp;geneID=2580&amp;typeOption=gene&amp;which=2&amp;pubOrderType=pubD&amp;typeSubmit=GO&amp;check=y">HuGE Navigator</a>
</li>
<li>
<a href="http://www.genome.jp/dbget-bin/www_bget?hsa:2580">KEGG</a>
</li>
<li>
<a href="https://reactome.org/content/query?q=UniProt:O14976">Reactome</a>
</li>
</ul>
</div>
</div>
<div class="portlet brieflink dis-general-info">
<div class="portlet_head">
<div class="portlet_title">
<h3>General information</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_GeneralInfo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter"></a>
</div>
<div class="portlet_content">
<ul>
<li>
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<div class="ralinkpop offscreen_noflow">GAK cyclin G associated kinase [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:2580</div></div>
<div class="tertiary">Gene</div>
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<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=2" href="/portal/utils/pageresolver.fcgi?recordid=67ca032ef4a390645e048cb4">cyclin-G-associated kinase isoform 1 [Homo sapiens]</a>
<div class="ralinkpop offscreen_noflow">cyclin-G-associated kinase isoform 1 [Homo sapiens]<div class="brieflinkpopdesc">gi|157384971|ref|NP_005246.2|</div></div>
<div class="tertiary">Protein</div>
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<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=3" href="/portal/utils/pageresolver.fcgi?recordid=67ca032db15b832ebcd31686">forkhead box protein C1 [Homo sapiens]</a>
<div class="ralinkpop offscreen_noflow">forkhead box protein C1 [Homo sapiens]<div class="brieflinkpopdesc">gi|119395716|ref|NP_001444.2|</div></div>
<div class="tertiary">Protein</div>
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<div class="ralinkpop offscreen_noflow">FNIP1 folliculin interacting protein 1 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:96459</div></div>
<div class="tertiary">Gene</div>
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<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=5" href="/portal/utils/pageresolver.fcgi?recordid=67ca032aa68b6b5afc34751f">folliculin-interacting protein 1 isoform 1 [Homo sapiens]</a>
<div class="ralinkpop offscreen_noflow">folliculin-interacting protein 1 isoform 1 [Homo sapiens]<div class="brieflinkpopdesc">gi|120953291|ref|NP_588613.2|</div></div>
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