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<div class="search"><div class="search_form"><label for="database" class="offscreen_noflow">Search database</label><select id="database"><optgroup label="Recent"><option value="pubmed">PubMed</option><option value="clinvar">ClinVar</option><option value="medgen">MedGen</option><option value="books" class="last">Books</option></optgroup><optgroup label="All"><option value="gquery">All Databases</option><option value="assembly" data-ac_dict="assembly">Assembly</option><option value="biocollections">Biocollections</option><option value="bioproject">BioProject</option><option value="biosample">BioSample</option><option value="books">Books</option><option value="clinvar">ClinVar</option><option value="cdd">Conserved Domains</option><option value="gap">dbGaP</option><option value="dbvar">dbVar</option><option value="gene" selected="selected" data-ac_dict="gene">Gene</option><option value="genome" data-ac_dict="genome">Genome</option><option value="gds">GEO DataSets</option><option value="geoprofiles">GEO Profiles</option><option value="gtr">GTR</option><option value="ipg">Identical Protein Groups</option><option value="medgen">MedGen</option><option value="mesh">MeSH</option><option value="nlmcatalog">NLM Catalog</option><option value="nuccore" data-ac_dict="nuccore">Nucleotide</option><option value="omim">OMIM</option><option value="pmc">PMC</option><option value="protein" data-ac_dict="protein">Protein</option><option value="proteinclusters">Protein Clusters</option><option value="protfam">Protein Family Models</option><option value="pcassay">PubChem BioAssay</option><option value="pccompound">PubChem Compound</option><option value="pcsubstance">PubChem Substance</option><option value="pubmed">PubMed</option><option value="snp">SNP</option><option value="sra">SRA</option><option value="structure">Structure</option><option value="taxonomy">Taxonomy</option><option value="toolkit">ToolKit</option><option value="toolkitall">ToolKitAll</option><option value="toolkitbookgh">ToolKitBookgh</option></optgroup></select><div class="nowrap"><label for="term" class="offscreen_noflow" accesskey="/">Search term</label><div class="nowrap"><input type="text" name="term" id="term" title="Search Gene. Use up and down arrows to choose an item from the autocomplete." value="" class="jig-ncbiclearbutton jig-ncbiautocomplete" data-jigconfig="dictionary:'gene',disableUrl:'NcbiSearchBarAutoComplCtrl'" autocomplete="off" data-sbconfig="ds:'no',pjs:'yes',afs:'yes'" /></div><button id="search" type="submit" class="button_search nowrap" cmd="go">Search</button></div></div><ul class="searchlinks inline_list"><set></set><li><a href="/gene/advanced">Advanced</a></li><li class="help"><a id="help" class="jig-ncbihelpwindow" target="ncbihelp" name="help" href="/books/NBK3841/">Help</a></li></ul></div>
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<div class="facet_cont" data-db="gene" data-default_grps="fg_gene-sources,fg_categories,fg_sequence-content,fg_status" data-sd="db:'gene',op:'select',term:'',qk:'4087',linkname:'',idsfromresult:'23368',extra:''"><ul class="facet" data-filter_id="gene-sources" id="_gene-sources"><li class="filter_grp "><div class="clearfix"><h3>Gene sources</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="genomic">Genomic</a></li></ul></li></ul><ul class="facet" data-filter_id="categories" id="_categories"><li class="filter_grp "><div class="clearfix"><h3>Categories</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="alt-splicing">Alternatively spliced</a></li><li class="fil_val"><a href="#" data-value_id="annotated-genes">Annotated genes</a></li><li class="fil_val"><a href="#" data-value_id="gene-type-protein-coding">Protein-coding</a></li></ul></li></ul><ul class="facet" data-filter_id="sequence-content" id="_sequence-content"><li class="filter_grp "><div class="clearfix"><h3>Sequence content</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="seq-ccds">CCDS</a></li><li class="fil_val"><a href="#" data-value_id="seq-ensembl">Ensembl</a></li><li class="fil_val"><a href="#" data-value_id="refseq">RefSeq</a></li><li class="fil_val"><a href="#" data-value_id="seq-refseqgene">RefSeqGene</a></li></ul></li></ul><ul class="facet" data-filter_id="status" id="_status"><li class="filter_grp "><div class="clearfix"><h3>Status</h3><a href="#" data-value_id="" class="clear clear_show">Clear</a></div><ul><li class="fil_val selected"><a href="#" data-value_id="current-only">Current</a><span class="fcount">(1)</span></li></ul></li></ul><div id="chr-location-facet-wrapper" data-bid="MCID_67c9e482d74f67691041dba5" data-hid="MCID_67c90f2d64f30b25346ccae2" data-qky="4087" class="disabled" style="display:none"><ul class="facet" data-filter_id="chromosomal-region" id="_chromosomal-region" data-of="yes"><li class="filter_grp of_grp"><div class="clearfix"><h3>Chromosome locations</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><a id="facet_ofchromosomal-region" href="#facet_of_divchromosomal-region" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'middle left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '375px'" data-value_id="fetch_more">more...</a><div id="facet_of_divchromosomal-region" style="display:none;" class="of_popup"><h4>Chromosome locations</h4><label for="organism-filter" style="width:100%;margin-bottom:.2em;" class="">Select an organism by typing or scrolling</label><input type="text" placeholder="Enter text to narrow down the list" id="organism-filter" style="width:98%;" autocomplete="off" /><br /><div id="chr-region-tax-list"><select id="of_chromosomal-region" size="9" class="chr-region-tax-list" style="width:100%;"></select></div><div id="chr-location-info-ctrl" data-disabled="disabled"><div class="chr-field"><label for="chr-name">Chromosome</label><br /><select id="chr-name" class="chr-field" disabled="disabled"></select></div><div class="chr-field"><label for="chr-from">From</label><br /><input type="text" name="chr-from" id="chr-from" disabled="disabled" class="chr-field" /></div><div class="chr-field"><label for="chr-to">To</label><br /><input type="text" name="chr-to" id="chr-to" disabled="disabled" class="chr-field" /></div></div><div class="actions clearfix"><button class="jig-ncbibutton of_add apply-chr" data-jigconfig="'color': 'ui-ncbibutton-blue'">Apply</button></div></div></ul></li></ul></div><ul class="facet facet_reset"><li><a href="#" data-value_id="reset">Clear all</a></li></ul><ul class="facet_tools"><li><a id="more_filter_groups_link" href="#more_filter_groups" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'top left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '180px'">
Show additional filters</a></li><div id="more_filter_groups" style="display:none;" class="facets_dialog"><button class="ui-ncbipopper-close-button ui-ncbipopper-close-button-generated ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-blue" generated="true" role="button" aria-disabled="false"><span class="ui-button-text">x</span></button><h4>Additional filters</h4><ul class="filter_groups_more facet"><li><input type="checkbox" id="fg_gene-sources" /><label for="fg_gene-sources">Gene sources</label></li><li><input type="checkbox" id="fg_categories" /><label for="fg_categories">Categories</label></li><li><input type="checkbox" id="fg_sequence-content" /><label for="fg_sequence-content">Sequence content</label></li><li><input type="checkbox" id="fg_status" /><label for="fg_status">Status</label></li><li><input type="checkbox" id="fg_chromosomal-region" /><label for="fg_chromosomal-region">Chromosome locations</label></li><li><input id="fg_field_search" type="checkbox" /><label for="fg_field_search">Search fields</label></li></ul><div class="actions clearfix"><button class="filter_groups_more_apply jig-ncbibutton primary-action" id="filter_groups_apply" data-jigconfig="'color': 'ui-ncbibutton-blue'">Show</button></div></div></ul><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetsUrlFrag" sid="1" type="hidden" value="filters=current-only" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetSubmitted" sid="1" type="hidden" value="false" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.BMFacets" sid="1" type="hidden" value="" /></div>
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<h1 class="title" id="gene-name"><span class="gn" style="padding-right:.5em;">PPP1R13B</span> protein phosphatase 1 regulatory subunit 13B [ <em class="tax">Homo sapiens</em> (human)
]
</h1>
<span class="geneid">Gene ID: 23368, updated on
4-Mar-2025</span>
</div>
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<div class="rprt-section gene-summary">
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<dl id="summaryDl">
<dt class="noline"> Official
Symbol</dt>
<dd class="noline">PPP1R13B<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
<dt> Official
Full Name</dt>
<dd>protein phosphatase 1 regulatory subunit 13B<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
<dt>Primary source</dt>
<dd>
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:14950" data-gblink-text="Ensembl">HGNC:HGNC:14950</a>
</dd>
<dt>See related</dt>
<dd>
<a href="http://www.ensembl.org/id/ENSG00000088808" data-gblink-text="Ensembl" class="genome-browser-link" data-genome-browser-link-sort="5" data-gb-url="http://www.ensembl.org/loc/ENSG00000088808">Ensembl:ENSG00000088808</a>
<a href="https://www.ncbi.nlm.nih.gov/omim/606455" data-gblink-text="Ensembl" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=606455">MIM:606455;</a>
<a href="https://www.alliancegenome.org/gene/HGNC:14950" data-gblink-text="Ensembl" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=HGNC:14950">AllianceGenome:HGNC:14950</a>
</dd>
<dt>Gene type</dt>
<dd>protein coding</dd>
<dt>RefSeq status</dt>
<dd>REVIEWED</dd>
<dt>Organism</dt>
<dd class="tax">
<a href="/Taxonomy/Browser/wwwtax.cgi?id=9606" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=9606">Homo sapiens</a>
</dd>
<dt>Lineage</dt>
<dd class="tax">Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo</dd>
<dt>Also known as</dt>
<dd>p85; ASPP1; p53BP2-like</dd>
<dt>Summary</dt>
<dd>This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008]</dd>
<dt>Expression</dt>
<dd>Broad expression in thyroid (RPKM 17.5), testis (RPKM 15.0) and 24 other tissues <a href="#gene-expression">See more</a></dd>
<dt>Orthologs</dt>
<dd class="ortholog-links">
<a href="https://www.ncbi.nlm.nih.gov/gene/21981">mouse</a>
<a href="/gene/23368/ortholog/">all</a>
</dd>
<dt style="padding-top:.5em;">
<span class="new-icon">NEW</span>
</dt>
<dd style="padding-top:.5em;">
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/23368/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="gene_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Gene table</a></strong>
<br />
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/23368/products/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="transcript_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Transcript table</a></strong>
</dd>
</dl>
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<div class="rprt-section gene-genomic-context">
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<div class="gt_cont_contents">
<div style="float:right"><span>See PPP1R13B in </span><a href="/genome/gdv/?context=gene&amp;acc=23368" class="link-to-gdv genome-browser-link" data-genome-browser-link-sort="1" data-acc="GCF_000001405.40">Genome Data Viewer</a> </div>
<dl class="dl-chr-info" style="float:left;margin-top:0;">
<dt>Location: </dt>
<dd>
<span style="display:inline-block;">14q32.33</span>
</dd>
</dl>
</div>
<dl class="dl-chr-info exon-count">
<dt>Exon count: </dt>
<dd>23</dd>
</dl>
<div class="ui-ncbigrid-outer-div" id="genomic-context-tbl-location">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-jigconfig="">
<thead>
<tr>
<th style="max-width:15%">Annotation release</th>
<th style="max-width:10%">Status</th>
<th>Assembly</th>
<th>
<span title="Chromosome">Chr</span>
</th>
<th>Location</th>
</tr>
</thead>
<tbody>
<tr>
<td>RS_2024_08</td>
<td>current</td>
<td>GRCh38.p14 (<a href="/assembly/GCF_000001405.40/" ref="ncbi_uid=23368&amp;link_uid=GCF_000001405.40">GCF_000001405.40</a>)</td>
<td>14</td>
<td>NC_000014.9 (103733195..103848814, complement) </td>
</tr>
<tr>
<td>RS_2024_08</td>
<td>current</td>
<td>T2T-CHM13v2.0 (<a href="/assembly/GCF_009914755.1/" ref="ncbi_uid=23368&amp;link_uid=GCF_009914755.1">GCF_009914755.1</a>)</td>
<td>14</td>
<td>NC_060938.1 (97969263..98085448, complement) </td>
</tr>
<tr>
<td>RS_2024_09</td>
<td>previous assembly</td>
<td>GRCh37.p13 (<a href="/assembly/GCF_000001405.25/" ref="ncbi_uid=23368&amp;link_uid=GCF_000001405.25">GCF_000001405.25</a>)</td>
<td>14</td>
<td>NC_000014.8 (104199532..104313912, complement) </td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
<p class="withnote margin_t2em"><strong>Chromosome 14 - NC_000014.9</strong><img usemap="#nbrMap23368_568815584" border="0" alt="Genomic Context describing neighboring genes" src="/gutils/geneneighb.fcgi?geneid=23368&amp;nuc_gi=568815584&amp;n0=LOC105370688&amp;n1=LOC130056592&amp;n2=LOC130056593&amp;n3=LOC130056594&amp;n4=KLC1&amp;n5=LOC130056595&amp;n6=LOC130056596&amp;n7=LOC130056597&amp;n8=LOC127828780&amp;n9=LOC130056598&amp;n10=LOC127828781&amp;n11=LOC129390671&amp;n12=XRCC3&amp;n13=LOC130056599&amp;n14=LOC127828782&amp;n15=LOC127828783&amp;n16=LOC127828784&amp;n17=LOC130056600&amp;n18=LOC130056601&amp;n19=ZFYVE21&amp;n20=LOC130056602&amp;n21=LOC130056603&amp;n22=LOC130056604&amp;n23=LOC127828785&amp;n24=LOC127828786&amp;n25=PPP1R13B&amp;n26=LOC127828787&amp;n27=LOC130056605&amp;n28=LOC127828788&amp;n29=LOC127828789&amp;n30=LOC124900347&amp;n31=LOC130056606&amp;n32=LOC130056607&amp;n33=LOC130056608&amp;n34=LOC130056609&amp;n35=PPP1R13B-DT&amp;n36=LOC130056610&amp;n37=LOC130056611&amp;n38=LOC130056612&amp;n39=LOC105370689&amp;n40=LOC130056613&amp;n41=LOC130056614&amp;n42=LOC121838602&amp;n43=LOC127828790&amp;n44=LOC130056615&amp;n45=LOC127828791&amp;n46=ATP5MJ&amp;n47=LOC127828792" /><map name="nbrMap23368_568815584" id="nbrMap23368_568815584">
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC105370688')" onMouseOut="hidetip()" coords="2,23,72,31" alt="Neighboring gene uncharacterized LOC105370688" href="/gene/105370688" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 9109')" onMouseOut="hidetip()" coords="3,35,73,43" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9109" href="/gene/130056592" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 6163')" onMouseOut="hidetip()" coords="4,47,74,55" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6163" href="/gene/130056593" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 6164')" onMouseOut="hidetip()" coords="4,59,74,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6164" href="/gene/130056594" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 6165')" onMouseOut="hidetip()" coords="4,71,74,79" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6165" href="/gene/130056595" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 6166')" onMouseOut="hidetip()" coords="5,83,75,91" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6166" href="/gene/130056596" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 6167')" onMouseOut="hidetip()" coords="5,95,75,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6167" href="/gene/130056597" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr14:104106328-104106828')" onMouseOut="hidetip()" coords="17,107,87,115" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:104106328-104106828" href="/gene/127828780" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 6168')" onMouseOut="hidetip()" coords="22,119,92,127" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6168" href="/gene/130056598" />
<area shape="rect" onMouseOver="showtip(this,event,'kinesin light chain 1')" onMouseOut="hidetip()" coords="44,131,154,139" alt="Neighboring gene kinesin light chain 1" href="/gene/3831" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac hESC enhancer GRCh37_chr14:104140157-104140656')" onMouseOut="hidetip()" coords="58,143,128,151" alt="Neighboring gene H3K27ac hESC enhancer GRCh37_chr14:104140157-104140656" href="/gene/127828781" />
<area shape="rect" onMouseOver="showtip(this,event,'MPRA-validated peak2255 silencer')" onMouseOut="hidetip()" coords="77,23,147,31" alt="Neighboring gene MPRA-validated peak2255 silencer" href="/gene/129390671" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 9110')" onMouseOut="hidetip()" coords="93,35,163,43" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9110" href="/gene/130056599" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:104172251-104172810')" onMouseOut="hidetip()" coords="98,47,168,55" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:104172251-104172810" href="/gene/127828782" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:104172811-104173372')" onMouseOut="hidetip()" coords="98,59,168,67" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:104172811-104173372" href="/gene/127828783" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:104180589-104181274')" onMouseOut="hidetip()" coords="108,71,178,79" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:104180589-104181274" href="/gene/127828784" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 6170')" onMouseOut="hidetip()" coords="109,83,179,91" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6170" href="/gene/130056600" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 6171')" onMouseOut="hidetip()" coords="109,95,179,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6171" href="/gene/130056601" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 6172')" onMouseOut="hidetip()" coords="110,107,180,115" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6172" href="/gene/130056602" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 6173')" onMouseOut="hidetip()" coords="110,119,180,127" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6173" href="/gene/130056603" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 6174')" onMouseOut="hidetip()" coords="111,155,181,163" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6174" href="/gene/130056604" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr14:104184511-104185021')" onMouseOut="hidetip()" coords="113,167,183,175" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:104184511-104185021" href="/gene/127828785" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr14:104187639-104188139')" onMouseOut="hidetip()" coords="116,179,186,187" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:104187639-104188139" href="/gene/127828786" />
<area shape="rect" onMouseOver="showtip(this,event,'X-ray repair cross complementing 3')" onMouseOut="hidetip()" coords="123,191,171,199" alt="Neighboring gene X-ray repair cross complementing 3" href="/gene/7517" />
<area shape="rect" onMouseOver="showtip(this,event,'zinc finger FYVE-type containing 21')" onMouseOut="hidetip()" coords="135,143,193,151" alt="Neighboring gene zinc finger FYVE-type containing 21" href="/gene/79038" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:104209353-104210134')" onMouseOut="hidetip()" coords="143,203,213,211" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:104209353-104210134" href="/gene/127828787" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 6175')" onMouseOut="hidetip()" coords="150,23,220,31" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6175" href="/gene/130056605" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac hESC enhancer GRCh37_chr14:104260985-104261486')" onMouseOut="hidetip()" coords="206,35,276,43" alt="Neighboring gene H3K27ac hESC enhancer GRCh37_chr14:104260985-104261486" href="/gene/127828788" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac hESC enhancer GRCh37_chr14:104261487-104261986')" onMouseOut="hidetip()" coords="206,47,276,55" alt="Neighboring gene H3K27ac hESC enhancer GRCh37_chr14:104261487-104261986" href="/gene/127828789" />
<area shape="rect" onMouseOver="showtip(this,event,'small nucleolar RNA SNORD51')" onMouseOut="hidetip()" coords="209,59,279,67" alt="Neighboring gene small nucleolar RNA SNORD51" href="/gene/124900347" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 9111')" onMouseOut="hidetip()" coords="221,23,291,31" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9111" href="/gene/130056606" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 9112')" onMouseOut="hidetip()" coords="237,71,307,79" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9112" href="/gene/130056607" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 6176')" onMouseOut="hidetip()" coords="270,83,340,91" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6176" href="/gene/130056608" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 6177')" onMouseOut="hidetip()" coords="270,95,340,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6177" href="/gene/130056609" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 6178')" onMouseOut="hidetip()" coords="271,107,341,115" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6178" href="/gene/130056610" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 6179')" onMouseOut="hidetip()" coords="271,119,341,127" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6179" href="/gene/130056611" />
<area shape="rect" onMouseOver="showtip(this,event,'PPP1R13B divergent transcript')" onMouseOut="hidetip()" coords="276,131,345,139" alt="Neighboring gene PPP1R13B divergent transcript" href="/gene/145216" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 6180')" onMouseOut="hidetip()" coords="300,23,370,31" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6180" href="/gene/130056612" />
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC105370689')" onMouseOut="hidetip()" coords="300,35,372,43" alt="Neighboring gene uncharacterized LOC105370689" href="/gene/105370689" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 6181')" onMouseOut="hidetip()" coords="300,47,370,55" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6181" href="/gene/130056613" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 9113')" onMouseOut="hidetip()" coords="301,59,371,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 9113" href="/gene/130056614" />
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 8463')" onMouseOut="hidetip()" coords="310,71,380,79" alt="Neighboring gene Sharpr-MPRA regulatory region 8463" href="/gene/121838602" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:104347808-104348489')" onMouseOut="hidetip()" coords="312,143,382,151" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:104347808-104348489" href="/gene/127828790" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 6182')" onMouseOut="hidetip()" coords="336,155,406,163" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6182" href="/gene/130056615" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr14:104377123-104377623')" onMouseOut="hidetip()" coords="347,83,417,91" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:104377123-104377623" href="/gene/127828791" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:104387521-104388196')" onMouseOut="hidetip()" coords="353,95,423,103" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:104387521-104388196" href="/gene/127828792" />
<area shape="rect" onMouseOver="showtip(this,event,'ATP synthase membrane subunit j')" onMouseOut="hidetip()" coords="379,23,423,31" alt="Neighboring gene ATP synthase membrane subunit j" href="/gene/9556" />
</map>
</p>
</div>
</div>
<div class="rprt-section gene-genomic-regions-transcripts-products">
<section class="rprt-section-header" id="genomic-regions-transcripts-products">
<h2 id="header-genomic-regions-transcripts-products">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-regions-transcripts-products .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Genomic regions, transcripts, and products</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Genomic_Regions_Transcripts_a" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div>
<div style="text-align:right;">Go to <a href="#reference-sequences">reference sequence details</a></div>
</div>
<div>
<p class="choose">
<label for="accession" class="label">Genomic Sequence: </label>
<select name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.accessionList" sid="1" id="accessionList" data-taxid="9606" data-geneid="23368">
<option value="NC_000014.9_103733194_103848813">NC_000014.9 Chromosome 14 Reference GRCh38.p14 Primary Assembly</option>
<option value="NG_046915.1_6392_120772">NG_046915.1 RefSeqGene</option>
<option value="NC_060938.1_97969262_98085447">NC_060938.1 Chromosome 14 Alternate T2T-CHM13v2.0</option>
<option value="NC_000014.8_104199531_104313911">NC_000014.8 Chromosome 14 Reference GRCh37.p13 Primary Assembly</option>
</select>
</p>
</div>
<div id="NC_000014" class="divAccession">
<div class="seq-viewer">
<p class="note-link">
<strong>Go to nucleotide:</strong>
<a title="Nucleotide Graphic report" href="/nuccore/NC_000014.9?report=graph&amp;from=103715851&amp;to=103866156&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=NC_000014.9">Graphics</a>
<a title="Nucleotide FASTA report" href="/nuccore/NC_000014.9?report=fasta&amp;from=103733195&amp;to=103848814&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=NC_000014.9">FASTA</a>
<a title="Nucleotide GenBank report" href="/nuccore/NC_000014.9?report=genbank&amp;from=103733195&amp;to=103848814&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=NC_000014.9">GenBank</a>
</p>
<div id="divNC_000014" class="SeqViewerApp" style="clear:both;" data-sv="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000014.9&amp;from=103715851&amp;to=103866156&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.40">
<a href="?appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000014.9&amp;from=103715851&amp;to=103866156&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.40"></a>
</div>
</div>
</div>
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000014.9" sid="1" type="hidden" id="nucleotideLink_NC_000014_9_103733194_103848813" value="&lt;p class=&quot;note-link&quot;&gt;&lt;strong&gt;Go to nucleotide:&lt;/strong&gt;&lt;a title=&quot;Nucleotide Graphic report&quot; href=&quot;/nuccore/NC_000014.9?report=graph&amp;amp;from=103715851&amp;amp;to=103866156&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.40&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=23368&amp;amp;link_uid=NC_000014.9&quot;&gt;Graphics&lt;/a&gt;&lt;a title=&quot;Nucleotide FASTA report&quot; href=&quot;/nuccore/NC_000014.9?report=fasta&amp;amp;from=103733195&amp;amp;to=103848814&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=23368&amp;amp;link_uid=NC_000014.9&quot;&gt;FASTA&lt;/a&gt;&lt;a title=&quot;Nucleotide GenBank report&quot; href=&quot;/nuccore/NC_000014.9?report=genbank&amp;amp;from=103733195&amp;amp;to=103848814&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=23368&amp;amp;link_uid=NC_000014.9&quot;&gt;GenBank&lt;/a&gt;&lt;/p&gt;" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000014.9" sid="1" type="hidden" id="relString_NC_000014_9_103733194_103848813" value="appname=ncbigene&amp;amp;embedded=true&amp;amp;noslider=1&amp;amp;id=NC_000014.9&amp;amp;from=103715851&amp;amp;to=103866156&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.40" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NG_046915.1" sid="1" type="hidden" id="nucleotideLink_NG_046915_1_6392_120772" value="&lt;p class=&quot;note-link&quot;&gt;&lt;strong&gt;Go to nucleotide:&lt;/strong&gt;&lt;a title=&quot;Nucleotide Graphic report&quot; href=&quot;/nuccore/NG_046915.1?report=graph&amp;amp;from=1&amp;amp;to=137929&amp;amp;tracks=[key:sequence_track,name:Sequence,display_name:Sequence,category:Sequence,annots:Sequence,ShowLabel:false][key:gene_model_track,name:Genes---Unnamed,display_name:Genes,annots:Unnamed,Options:ShowAllButGenes,SNPs:false,CDSProductFeats:false,ShowLabelsForAllFeatures:true,HighlightMode:2][key:SNP_track,name:SNP,annots:SNP,Layout:Adaptive][key:SNP_Bins_track,name:Clinical Variants][key:SNP_Bins_track,name:Cited Variants][key:GWAS_track,name:GWAS Tracks,display_name:Association Results][key:alignment_track,category:Alignments,annots:Unnamed][key:alignment_track,category:Alignments,annots:NA000079160.1][key:alignment_track,category:Alignments,annots:NA000010065.1]&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=23368&amp;amp;link_uid=NG_046915.1&quot;&gt;Graphics&lt;/a&gt;&lt;a title=&quot;Nucleotide FASTA report&quot; href=&quot;/nuccore/NG_046915.1?report=fasta&amp;amp;from=6393&amp;amp;to=120773&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=23368&amp;amp;link_uid=NG_046915.1&quot;&gt;FASTA&lt;/a&gt;&lt;a title=&quot;Nucleotide GenBank report&quot; href=&quot;/nuccore/NG_046915.1?report=genbank&amp;amp;from=6393&amp;amp;to=120773&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=23368&amp;amp;link_uid=NG_046915.1&quot;&gt;GenBank&lt;/a&gt;&lt;/p&gt;" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NG_046915.1" sid="1" type="hidden" id="relString_NG_046915_1_6392_120772" value="appname=ncbigene&amp;amp;embedded=true&amp;amp;noslider=1&amp;amp;id=NG_046915.1&amp;amp;from=1&amp;amp;to=137929&amp;amp;tracks=[key:sequence_track,name:Sequence,display_name:Sequence,category:Sequence,annots:Sequence,ShowLabel:false][key:gene_model_track,name:Genes---Unnamed,display_name:Genes,annots:Unnamed,Options:ShowAllButGenes,SNPs:false,CDSProductFeats:false,ShowLabelsForAllFeatures:true,HighlightMode:2][key:SNP_track,name:SNP,annots:SNP,Layout:Adaptive][key:SNP_Bins_track,name:Clinical Variants][key:SNP_Bins_track,name:Cited Variants][key:GWAS_track,name:GWAS Tracks,display_name:Association Results][key:alignment_track,category:Alignments,annots:Unnamed][key:alignment_track,category:Alignments,annots:NA000079160.1][key:alignment_track,category:Alignments,annots:NA000010065.1]" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_060938.1" sid="1" type="hidden" id="nucleotideLink_NC_060938_1_97969262_98085447" value="&lt;p class=&quot;note-link&quot;&gt;&lt;strong&gt;Go to nucleotide:&lt;/strong&gt;&lt;a title=&quot;Nucleotide Graphic report&quot; href=&quot;/nuccore/NC_060938.1?report=graph&amp;amp;from=97951834&amp;amp;to=98102875&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_009914755.1&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=23368&amp;amp;link_uid=NC_060938.1&quot;&gt;Graphics&lt;/a&gt;&lt;a title=&quot;Nucleotide FASTA report&quot; href=&quot;/nuccore/NC_060938.1?report=fasta&amp;amp;from=97969263&amp;amp;to=98085448&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=23368&amp;amp;link_uid=NC_060938.1&quot;&gt;FASTA&lt;/a&gt;&lt;a title=&quot;Nucleotide GenBank report&quot; href=&quot;/nuccore/NC_060938.1?report=genbank&amp;amp;from=97969263&amp;amp;to=98085448&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=23368&amp;amp;link_uid=NC_060938.1&quot;&gt;GenBank&lt;/a&gt;&lt;/p&gt;" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_060938.1" sid="1" type="hidden" id="relString_NC_060938_1_97969262_98085447" value="appname=ncbigene&amp;amp;embedded=true&amp;amp;noslider=1&amp;amp;id=NC_060938.1&amp;amp;from=97951834&amp;amp;to=98102875&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_009914755.1" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000014.8" sid="1" type="hidden" id="nucleotideLink_NC_000014_8_104199531_104313911" value="&lt;p class=&quot;note-link&quot;&gt;&lt;strong&gt;Go to nucleotide:&lt;/strong&gt;&lt;a title=&quot;Nucleotide Graphic report&quot; href=&quot;/nuccore/NC_000014.8?report=graph&amp;amp;from=104182374&amp;amp;to=104331068&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.25&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=23368&amp;amp;link_uid=NC_000014.8&quot;&gt;Graphics&lt;/a&gt;&lt;a title=&quot;Nucleotide FASTA report&quot; href=&quot;/nuccore/NC_000014.8?report=fasta&amp;amp;from=104199532&amp;amp;to=104313912&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=23368&amp;amp;link_uid=NC_000014.8&quot;&gt;FASTA&lt;/a&gt;&lt;a title=&quot;Nucleotide GenBank report&quot; href=&quot;/nuccore/NC_000014.8?report=genbank&amp;amp;from=104199532&amp;amp;to=104313912&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=23368&amp;amp;link_uid=NC_000014.8&quot;&gt;GenBank&lt;/a&gt;&lt;/p&gt;" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000014.8" sid="1" type="hidden" id="relString_NC_000014_8_104199531_104313911" value="appname=ncbigene&amp;amp;embedded=true&amp;amp;noslider=1&amp;amp;id=NC_000014.8&amp;amp;from=104182374&amp;amp;to=104331068&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.25" />
</div>
</div>
<div class="rprt-section gene-gene-expression">
<section class="rprt-section-header" id="gene-expression">
<h2 id="header-gene-expression">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-gene-expression .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Expression</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Expression" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div>
<div style="text-align:right;">
<a href="/gene/23368/?report=expression" data-url="/gene/23368/?report=expression" id="gene-expression-see-details">See details</a>
</div>
<div id="gene-expression-app" data-url="https://www.ncbi.nlm.nih.gov/gene/23368" data-report-type="summary">
<div>
<script type="text/javascript">
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Tissue-specific circular RNA induction during human fetal development
</option>
<option value="SRP056969" data-bioproject="PRJNA280600">
RNA sequencing of total RNA from 20 human tissues
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<option value="ERP003613" data-bioproject="PRJEB4337">
HPA RNA-seq normal tissues
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<ul id="project-summary">
<li id="project-summary-title">Project title:
Tissue-specific circular RNA induction during human fetal development
</li>
<li id="project-summary-desc">Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA</li>
<li id="project-summary-bioprojects">BioProject: <a href="/bioproject/PRJNA270632/">PRJNA270632</a>
</li>
<li id="project-summary-pubs">Publication:
<span><a href="/pubmed/26076956/">PMID 26076956</a></span>
</li>
<li id="project-summary-analysis-date">Analysis date: Mon Apr 2 22:54:59 2018</li>
</ul>
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<h3 id="relatedarticlesinpubmed">
<a href="#" class="jig-ncbitoggler-open">Related articles in PubMed</a>
</h3>
<div class="generefbl-link">
<ol class="generef-link">
<li>
<a href="/pubmed/21102414/" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=21102414">Downregulation of ASPP1 in gestational trophoblastic disease: correlation with hypermethylation, apoptotic activity and clinical outcome.</a>
<span class="pubmed-auth-date"> Mak VC, <em>et al</em>. Mod Pathol, 2011 Apr. PMID 21102414</span>
</li>
<li>
<a href="/pubmed/22068052/" ref="ordinalpos=2&amp;ncbi_uid=23368&amp;link_uid=22068052">An indirect role for ASPP1 in limiting p53-dependent p21 expression and cellular senescence.</a>
<span class="pubmed-auth-date"> Vigneron AM, <em>et al</em>. EMBO J, 2012 Jan 18. PMID 22068052, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC3261561/" ref="ordinalpos=0&amp;ncbi_uid=23368&amp;link_uid=PMC3261561">Free PMC Article</a></span></span>
</li>
<li>
<a href="/pubmed/32269211/" ref="ordinalpos=3&amp;ncbi_uid=23368&amp;link_uid=32269211">ASPP1 deficiency promotes epithelial-mesenchymal transition, invasion and metastasis in colorectal cancer.</a>
<span class="pubmed-auth-date"> Liu D, <em>et al</em>. Cell Death Dis, 2020 Apr 8. PMID 32269211, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC7142079/" ref="ordinalpos=0&amp;ncbi_uid=23368&amp;link_uid=PMC7142079">Free PMC Article</a></span></span>
</li>
<li>
<a href="/pubmed/16314841/" ref="ordinalpos=4&amp;ncbi_uid=23368&amp;link_uid=16314841">ASPP1, a common activator of TP53, is inactivated by aberrant methylation of its promoter in acute lymphoblastic leukemia.</a>
<span class="pubmed-auth-date"> Agirre X, <em>et al</em>. Oncogene, 2006 Mar 23. PMID 16314841</span>
</li>
<li>
<a href="/pubmed/23392125/" ref="ordinalpos=5&amp;ncbi_uid=23368&amp;link_uid=23392125">ASPP1 and ASPP2 bind active RAS, potentiate RAS signalling and enhance p53 activity in cancer cells.</a>
<span class="pubmed-auth-date"> Wang Y, <em>et al</em>. Cell Death Differ, 2013 Apr. PMID 23392125, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC3595493/" ref="ordinalpos=0&amp;ncbi_uid=23368&amp;link_uid=PMC3595493">Free PMC Article</a></span></span>
</li>
</ol>
<p class="see-all-pm">
<a href="/pubmed?LinkName=gene_pubmed&amp;from_uid=23368" title="See all 82 citations in Pubmed">See all (82) citations in PubMed</a>
</p>
</div>
</div>
<div class="generif-pubmed generif">
<h3 id="generifsgenereferencesintofunctions">
<a href="#" class="jig-ncbitoggler-open">GeneRIFs: Gene References Into Functions</a>
</h3>
<div>
<a href="/gene/about-generif" class="whatisthis">What's a GeneRIF?</a>
<div class="generefbl-link">
<ol class="generef-link">
<li class="gene-rif-popper">
<a href="/pubmed/32269211" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=32269211">ASPP1 deficiency promotes epithelial-mesenchymal transition, invasion and metastasis in colorectal cancer.</a>
<div id="gene-popper1" class="gene-rif-popper">Title: ASPP1 deficiency promotes epithelial-mesenchymal transition, invasion and metastasis in colorectal cancer.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/32987288" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=32987288">Apoptosis stimulating protein of p53 (ASPP) 1 and ASPP2 m-RNA expression in oral cancer.</a>
<div id="gene-popper2" class="gene-rif-popper">Title: Apoptosis stimulating protein of p53 (ASPP) 1 and ASPP2 m-RNA expression in oral cancer.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/28594407" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=28594407">results provide new insights into EGR-1/ASPP1 regulatory loop in sensitizing Quercetin-induced apoptosis. EGR-1/ASPP1, therefore, may be potentially used as therapeutic targets to improve cancer's response to pro-apoptosis treatments.</a>
<div id="gene-popper3" class="gene-rif-popper">Title: EGR-1/ASPP1 inter-regulatory loop promotes apoptosis by inhibiting cyto-protective autophagy.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/28103919" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=28103919">Results showed that the protein expression levels of ASPP1 in esophageal squamous cell carcinoma (ESCC) tissues and in paired noncancerous tissues were similar but was significantly associated with histological differentiation and invasive depth which suggest that it might be involved in the progression of ESCC.</a>
<div id="gene-popper4" class="gene-rif-popper">Title: Prognostic values of apoptosis-stimulating P53-binding protein 1 and 2 and their relationships with clinical characteristics of esophageal squamous cell carcinoma patients: a retrospective study.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/27177208" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=27177208">Increased expression of p53 and ASPP1 and downregulation of iASPP.</a>
<div id="gene-popper5" class="gene-rif-popper">Title: A novel all-trans retinoic acid derivative 4-amino2trifluoromethyl-phenyl retinate inhibits the proliferation of human hepatocellular carcinoma HepG2 cells by inducing G0/G1 cell cycle arrest and apoptosis via upregulation of p53 and ASPP1 and downregulation of iASPP.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/26595804" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=26595804">ASPP1/2-PP1 complexes are required for chromosome segregation and kinetochore-microtubule attachments.</a>
<div id="gene-popper6" class="gene-rif-popper">Title: ASPP1/2-PP1 complexes are required for chromosome segregation and kinetochore-microtubule attachments.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/25660448" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=25660448">ASPP1/2 interacted with centrosome linker protein C-Nap1. Co-depletion of ASPP1 and ASPP2 inhibited re-association of C-Nap1 with centrosome at the end of mitosis.</a>
<div id="gene-popper7" class="gene-rif-popper">Title: The tumor suppressor proteins ASPP1 and ASPP2 interact with C-Nap1 and regulate centrosome linker reassembly.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/23392125" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=23392125">ASPP1 and ASPP2 cooperate with oncogenic RAS to enhance the transcription and apoptotic function of p53.</a>
<div id="gene-popper8" class="gene-rif-popper">Title: ASPP1 and ASPP2 bind active RAS, potentiate RAS signalling and enhance p53 activity in cancer cells.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/23088536" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=23088536">When the Px(T)PxR motif is deleted or mutated via insertion of a phosphorylation site mimic (T311D), PP-1c fails to bind to all three ASPP proteins, ASPP1, ASPP2 and iASPP.</a>
<div id="gene-popper9" class="gene-rif-popper">Title: Molecular mechanisms underlying the interaction of protein phosphatase-1c with ASPP proteins.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/22552744" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=22552744">the mRNA expression of ASPP1 and ASPP2 was frequently dowregulated in tumor tissues, and this decreased significantly in samples expressing wild-type p53</a>
<div id="gene-popper10" class="gene-rif-popper">Title: Abnormal expression pattern of the ASPP family of proteins in human non-small cell lung cancer and regulatory functions on apoptosis through p53 by iASPP.</div>
</li>
</ol>
</div>
<div class="submit-genrif">
<span>Submit:</span>
<a href="/gene/submit-generif/?geneId=23368&amp;sym=PPP1R13B&amp;name=protein phosphatase 1 regulatory subunit 13B&amp;org=Homo sapiens">New GeneRIF</a>
<a href="/RefSeq/update.cgi?geneid=23368&amp;symbol=PPP1R13B;task=fixpub">Correction</a>
<a href="https://www.ncbi.nlm.nih.gov/gene?db=gene&amp;report=generif&amp;term=23368" class="seeall-generif">See all GeneRIFs (24)</a>
</div>
</div>
</div>
</div>
</div>
<div class="rprt-section gene-phenotypes">
<section class="rprt-section-header" id="phenotypes">
<h2 id="header-phenotypes">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-phenotypes .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Phenotypes</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Phenotype" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body info-phenotype">
<p class="nochild-link">
<a href="/gtr/tests/?term=PPP1R13B[gene]">Find tests for this gene in the NIH Genetic Testing Registry (GTR)</a>
</p>
<p class="nochild-link">
<a href="/gap/PheGenI?tab=1&amp;gene=23368">Review eQTL and phenotype association data in this region using PheGenI</a>
</p>
<div>
<h3 id="ebigwascatalog">EBI GWAS Catalog</h3>
<table class="jig-ncbigrid gtr-associated-cond" data-jigconfig="isPageable: true, pageSize: 10">
<thead>
<tr>
<th class="description">Description</th>
</tr>
</thead>
<tbody>
<tr>
<td>Biological insights from 108 schizophrenia-associated genetic loci.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/25056061">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/25056061">PubMed</a></span></div></div></div></td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
<div class="rprt-section gene-variation">
<section class="rprt-section-header" id="variation">
<h2 id="header-variation">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-variation .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Variation</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.variation" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<p class="nochild-link">
<a href="/clinvar/?term=PPP1R13B[gene]" ref="log$=recordlinks">See variants in ClinVar</a>
</p>
<p class="nochild-link">
<a href="/dbvar?LinkName=gene_dbvar&amp;from_uid=23368" ref="log$=recordlinks">See studies and variants in dbVar</a>
</p>
<p class="nochild-link">
<a href="/variation/view/?q=23368[geneid]&amp;assm=GCF_000001405.25" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh37.p13)">See Variation Viewer (GRCh37.p13)</a>
</p>
<p class="nochild-link">
<a href="/variation/view/?q=23368[geneid]" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh38)">See Variation Viewer (GRCh38)</a>
</p>
<set></set>
<set></set>
</div>
</div>
<div class="rprt-section gene-HIV-1-interactions">
<section class="rprt-section-header" id="HIV-1-interactions">
<h2 id="header-HIV-1-interactions">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-HIV-1-interactions .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">HIV-1 interactions</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.HIV1_interactions" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div class="fgrid">
<h3 id="proteininteractions">Protein interactions</h3>
<table summary="protein interactions" class="jig-ncbigrid">
<thead>
<tr>
<th id="hivprotein">Protein</th>
<th id="gene-hivprotein">Gene</th>
<th id="hivinter">Interaction</th>
<th id="hivpub">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="hivprotein">
<a href="/protein/28876544">Envelope surface glycoprotein gp120</a>
</td>
<td headers="gene-hivprotein">
<a href="/gene/155971">env</a>
</td>
<td headers="hivinter">HIV-1 gp120 upregulates the expression of protein phosphatase 1, regulatory subunit 13B (PPP1R13B) in human B cells</td>
<td headers="hivpub">
<a title="PubMed Id(s): 24162774" href="/pubmed/24162774">PubMed</a>
</td>
</tr>
</tbody>
</table>
<p class="withnote">
<a class="note" href="/genome/viruses/retroviruses/hiv-1/interactions/">Go to the HIV-1, Human Interaction Database </a>
</p>
</div>
</div>
</div>
<div class="rprt-section gene-pathways">
<section class="rprt-section-header" id="pathways">
<h2 id="header-pathways">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-pathways .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Pathways from PubChem</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<ul class="geneinfo-subsec infopathway">
<iframe title="Pathways in which the gene target is involved" class="pubchem-widget" scrolling="no" src="https://pubchem.ncbi.nlm.nih.gov/gene/23368#section=Pathways&amp;embed=true&amp;hide_all_headings=true&amp;page_size=25" style="border: 0; width: 100%;"></iframe>
<script type="text/javascript" src="https://pubchem.ncbi.nlm.nih.gov/pcfe/libs/iframeResizer.min.js"></script>
<script type="text/javascript">iFrameResize({log: false, checkOrigin: false}, '.pubchem-widget')</script>
</ul>
</div>
</div>
<div class="rprt-section gene-interactions">
<section class="rprt-section-header" id="interactions">
<h2 id="header-interactions">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-interactions .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Interactions</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Interactions" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<table summary="Gene Interaction" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/23368/data/interaction/',webserviceParams: 'p$l=Ajax&amp;p$debugoutput=off', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
<thead>
<tr>
<th id="inter-prod">Products</th>
<th id="inter-interactant">Interactant</th>
<th id="inter-otherGene">Other Gene</th>
<th id="inter-compl">Complex</th>
<th id="inter-source">Source</th>
<th id="inter-pubs">Pubs</th>
<th id="inter-desc">Description</th>
</tr>
</thead>
<tbody></tbody>
</table>
</div>
</div>
<div class="rprt-section gene-general-gene-info">
<section class="rprt-section-header" id="general-gene-info">
<h2 id="header-general-gene-info">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-gene-info .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">General gene information</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.General_Gene_Information" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body" style="">
<div id="gene-markers">
<h3 id="markers">
<a class="jig-ncbitoggler">Markers</a>
</h3>
<div>
<ul class="marker odd">
<li class="marker">RH78568 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=31287%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=31287">UniSTS:31287</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">SHGC-32210 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=40770%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=40770">UniSTS:40770</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">D14S1010 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=12613%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=12613">UniSTS:12613</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">G36171 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=26956%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=26956">UniSTS:26956</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">RH69614 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=30028%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=30028">UniSTS:30028</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">PPP1R13B_1759 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=280921%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=280921">UniSTS:280921</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">G36012 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=30055%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=30055">UniSTS:30055</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">G35763 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=15238%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=15238">UniSTS:15238</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">HSC0RB112 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=54680%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=54680">UniSTS:54680</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">G35416 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=31142%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=31142">UniSTS:31142</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">G35615 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=12220%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=12220">UniSTS:12220</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">A008C04 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=39637%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=39637">UniSTS:39637</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">RH120107 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=132313%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=132313">UniSTS:132313</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">G35800 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=23513%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=23513">UniSTS:23513</a></li></ul></li>
</ul>
<ul class="marker odd">
<li class="marker">G19698 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=81140%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=81140">UniSTS:81140</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">A001V41 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=81141%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=81141">UniSTS:81141</a></li></ul></li>
</ul>
</div>
</div>
<div></div>
<div class="infosec">
<h3 id="homology">
<a class="jig-ncbitoggler-open">Homology</a>
</h3>
<ul class="geneinfo-subsec">
<li>
<a href="/gene/23368/ortholog/" id="ncbi-ortholog-link">NCBI Orthologs</a>
</li>
<a href="https://www.orthodb.org/?ncbi=23368" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8178" target="_blank">
Orthologs from OrthoDB
</a>
</ul>
</div>
<!--<component id="Gene_InfoPathway"/>-->
<div class="infosec info-comment" id="info-comment">
<h3 id="CloneNames">
<a class="jig-ncbitoggler-open">Clone Names</a>
</h3>
<ul class="geneinfo-subsec">
<li>KIAA0771 </li>
</ul>
</div>
<div class="gene-ontology infosec">
<h3 id="gene-ontology">
<a class="jig-ncbitoggler-open">
<span>Gene Ontology</span>
</a>
<a target="_blank" href="http://www.ebi.ac.uk/GOA" class="g-ontology-src" title="Provided by GOA">Provided by GOA</a>
</h3>
<div class="ontology-tables">
<div class="ui-ncbigrid-outer-div">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
<thead>
<tr>
<th class="col1">Function</th>
<th style="width:12%;">Evidence Code</th>
<th style="width:10%;">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0002039">enables p53 binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-1-0" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005515">enables protein binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
<div id="evidence-code-2-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/11684014,14729977,15231748,17043677,21513714,21998301,22321011,24366813,25416956,28330616,28514442,31413325,32296183,33961781" target="_blank" title="PubMed ID 11684014,14729977,15231748,17043677,21513714,21998301,22321011,24366813,25416956,28330616,28514442,31413325,32296183,33961781" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=11684014,14729977,15231748,17043677,21513714,21998301,22321011,24366813,25416956,28330616,28514442,31413325,32296183,33961781">PubMed</a> </td>
</tr>
</tbody>
</table>
</div>
</div>
<div class="ui-ncbigrid-outer-div">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
<thead>
<tr>
<th class="col1">Process</th>
<th style="width:12%;">Evidence Code</th>
<th style="width:10%;">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0072332">involved_in intrinsic apoptotic signaling pathway by p53 class mediator</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-1-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/11684014" target="_blank" title="PubMed ID 11684014" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=11684014">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0045786">involved_in negative regulation of cell cycle</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-2-1" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/14729977" target="_blank" title="PubMed ID 14729977" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=14729977">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0042981">involved_in regulation of apoptotic process</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-3-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
</tbody>
</table>
</div>
</div>
<div class="ui-ncbigrid-outer-div">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-config="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
<thead>
<tr>
<th class="col1">Component</th>
<th style="width:12%;">Evidence Code</th>
<th style="width:10%;">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005737">located_in cytoplasm</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-1-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/15782125" target="_blank" title="PubMed ID 15782125" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=15782125">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005829">located_in cytosol</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-2-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005654">located_in nucleoplasm</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-3-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005654">located_in nucleoplasm</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-4-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005634">is_active_in nucleus</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-5-2" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005634">located_in nucleus</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-6-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/11684014" target="_blank" title="PubMed ID 11684014" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=11684014">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0048471">located_in perinuclear region of cytoplasm</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-7-2" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005886">located_in plasma membrane</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-8-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-8-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
</div>
</div>
</div>
<div class="rprt-section gene-general-protein-info">
<section class="rprt-section-header" id="general-protein-info">
<h2 id="header-general-protein-info">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-protein-info .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">General protein information</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.General_Protein_Information" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<dl>
<dt>Preferred Names</dt>
<dd>apoptosis-stimulating of p53 protein 1</dd>
</dl>
<dl>
<dt>Names</dt>
<dd>apoptosis-stimulating protein of p53, 1</dd>
<dd>protein phosphatase 1, regulatory (inhibitor) subunit 13B</dd>
</dl>
</div>
</div>
<div class="rprt-section gene-reference-sequences">
<section class="rprt-section-header" id="reference-sequences">
<h2 id="header-reference-sequences">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-reference-sequences .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">NCBI Reference Sequences (RefSeq)</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.NCBI_Reference_Sequences_RefS" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<p>
<span class="new-icon">NEW</span>
<strong>Try the new <a href="/datasets/tables/genes/?table_type=transcripts&amp;ids=23368&amp;utm_source=gene&amp;utm_medium=referral&amp;utm_campaign=refseq" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report." data-ga-category="refseq" data-ga-action="click_datasets_link" data-ga-label="transcript_table">Transcript table</a></strong>
</p>
<h3 class="genomerefseqs gene_std_toggler" id="refseqset-independent">
<a class="jig-ncbitoggler-open">RefSeqs maintained independently of Annotated
Genomes</a>
</h3>
<div class="genomerefseqs_slave">
<p class="desc"> These reference sequences exist independently of genome builds. <a href="#refseq-expl" id="expl-refseg">Explain</a></p>
<p id="refseq-expl"> These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in <a href="#geneGenomic regions, transcripts, and products">Genomic regions,
transcripts, and products</a> above. </p>
<h4 id="genomic-p74332384">Genomic </h4>
<ol>
<li>
<p>NG_046915.1 RefSeqGene</p>
<dl>
<dt>Range</dt>
<dd class="rs-range">
<span>6393..120773</span>
</dd>
<dt>Download</dt>
<dd><a href="/nuccore/NG_046915.1?from=6393&amp;to=120773&amp;report=genbank" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=NG_046915.1?from=6393&amp;to=120773&amp;report=genbank">GenBank</a>, <a href="/nuccore/NG_046915.1?from=6393&amp;to=120773&amp;report=fasta" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=NG_046915.1?from=6393&amp;to=120773&amp;report=fasta">FASTA</a>, <a href="/nuccore/NG_046915.1?from=1&amp;to=137929&amp;report=graph&amp;content=5" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=NG_046915.1?from=1&amp;to=137929&amp;report=graph&amp;content=5">Sequence Viewer (Graphics)</a></dd>
</dl>
</li>
</ol>
<h4 id="mrnaandproteins-p96557664">mRNA and Protein(s) </h4>
<ol>
<li>
<p><a href="/nuccore/NM_015316.3">NM_015316.3</a><a href="/protein/NP_056131.2">NP_056131.2</a>  apoptosis-stimulating of p53 protein 1</p>
<p>
<a href="/ipg/NP_056131.2/" ref="ncbi_uid=23368">See identical proteins and their annotated locations for NP_056131.2</a>
</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/AJ318887, AL049840, AW295594, BC035446, DB461586">AJ318887, AL049840, AW295594, BC035446, DB461586</a>
</dd>
<dt>Consensus CDS</dt>
<dd>
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&amp;GO=MainBrowse&amp;DATA=CCDS41997.1">CCDS41997.1</a>
</dd>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/B2RMX5" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">B2RMX5</a>, <a href="https://www.uniprot.org/uniprot/O94870" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">O94870</a>, <a href="https://www.uniprot.org/uniprot/Q96KQ4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">Q96KQ4</a></dd>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A3B3ISJ2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">A0A3B3ISJ2</a>
</dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000202556.9" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">ENSP00000202556.9</a>, <a href="http://www.ensembl.org/id/ENST00000202556.14" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">ENST00000202556.14</a></dd>
<dt class="clear"> Conserved Domains (5) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_056131.2">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=212887">cd11954</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1022</span><span class="cddto">1078</span></dt>
<dd class="clearfix"> SH3_ASPP1; Src Homology 3 domain of Apoptosis Stimulating of p53 protein 1</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238125">cd00204</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">886</span><span class="cddto">1009</span></dt>
<dd class="clearfix"> ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=293786">sd00045</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">892</span><span class="cddto">918</span></dt>
<dd class="clearfix"> ANK; ANK repeat [structural motif]</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=330553">cl25732</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">149</span><span class="cddto">317</span></dt>
<dd class="clearfix"> SMC_N; RecF/RecN/SMC N terminal domain</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=331285">cl26464</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">445</span><span class="cddto">863</span></dt>
<dd class="clearfix"> Atrophin-1; Atrophin-1 family</dd>
</dl>
</dd>
</dl>
</li>
</ol>
</div>
<h3 class="genomerefseqs gene_std_toggler" id="annotatedrefseq-title">
<a class="jig-ncbitoggler-open">RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08</a>
</h3>
<div class="genomerefseqs_slave">
<p class="desc"> The following sections contain reference sequences that belong to a
specific genome build. <a href="#" id="expl-genomes">Explain</a></p>
<p id="expl-genomes-desc" style="display:none">This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.</p>
<h3 id="refseq-sequencedescription-p51796400">Reference GRCh38.p14 Primary Assembly</h3>
<h4 id="genomic-p51796400">Genomic </h4>
<ol>
<li>
<p>NC_000014.9 Reference GRCh38.p14 Primary Assembly</p>
<dl>
<dt>Range</dt>
<dd class="rs-range">
<span>103733195..103848814 complement</span>
</dd>
<dt>Download</dt>
<dd><a href="/nuccore/NC_000014.9?from=103733195&amp;to=103848814&amp;report=genbank&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=NC_000014.9?from=103733195&amp;to=103848814&amp;report=genbank&amp;strand=true">GenBank</a>, <a href="/nuccore/NC_000014.9?from=103733195&amp;to=103848814&amp;report=fasta&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=NC_000014.9?from=103733195&amp;to=103848814&amp;report=fasta&amp;strand=true">FASTA</a>, <a href="/nuccore/NC_000014.9?from=103715851&amp;to=103866156&amp;report=graph&amp;content=5&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=NC_000014.9?from=103715851&amp;to=103866156&amp;report=graph&amp;content=5&amp;strand=true">Sequence Viewer (Graphics)</a></dd>
</dl>
</li>
</ol>
<h4 id="mrnaandproteins-p125784384">mRNA and Protein(s) </h4>
<ol>
<li>
<p><a href="/nuccore/XM_005267487.6">XM_005267487.6</a><a href="/protein/XP_005267544.1">XP_005267544.1</a>  apoptosis-stimulating of p53 protein 1 isoform X2</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A3B3ISJ2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">A0A3B3ISJ2</a>
</dd>
<dt class="clear"> Conserved Domains (8) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_005267544.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=212887">cd11954</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1090</span><span class="cddto">1146</span></dt>
<dd class="clearfix"> SH3_ASPP1; Src Homology 3 domain of Apoptosis Stimulating of p53 protein 1</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238125">cd00204</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">954</span><span class="cddto">1077</span></dt>
<dd class="clearfix"> ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=284015">pfam06484</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">780</span><span class="cddto">936</span></dt>
<dd class="clearfix"> Ten_N; Teneurin Intracellular Region</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=284686">pfam07321</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">222</span><span class="cddto">385</span></dt>
<dd class="clearfix"> YscO; Type III secretion protein YscO</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=289560">pfam12796</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">960</span><span class="cddto">1046</span></dt>
<dd class="clearfix"> Ank_2; Ankyrin repeats (3 copies)</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=290574">pfam13863</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">221</span><span class="cddto">315</span></dt>
<dd class="clearfix"> DUF4200; Domain of unknown function (DUF4200)</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=293786">sd00045</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">960</span><span class="cddto">986</span></dt>
<dd class="clearfix"> ANK; ANK repeat [structural motif]</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=298833">cl09111</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">276</span><span class="cddto">386</span></dt>
<dd class="clearfix"> Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_011536593.4">XM_011536593.4</a><a href="/protein/XP_011534895.1">XP_011534895.1</a>  apoptosis-stimulating of p53 protein 1 isoform X1</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A3B3ISJ2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">A0A3B3ISJ2</a>
</dd>
<dt class="clear"> Conserved Domains (8) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011534895.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=212887">cd11954</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1125</span><span class="cddto">1181</span></dt>
<dd class="clearfix"> SH3_ASPP1; Src Homology 3 domain of Apoptosis Stimulating of p53 protein 1</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=238125">cd00204</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">989</span><span class="cddto">1112</span></dt>
<dd class="clearfix"> ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=284015">pfam06484</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">857</span><span class="cddto">971</span></dt>
<dd class="clearfix"> Ten_N; Teneurin Intracellular Region</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=284686">pfam07321</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">222</span><span class="cddto">385</span></dt>
<dd class="clearfix"> YscO; Type III secretion protein YscO</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=289560">pfam12796</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">995</span><span class="cddto">1081</span></dt>
<dd class="clearfix"> Ank_2; Ankyrin repeats (3 copies)</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=290574">pfam13863</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">221</span><span class="cddto">315</span></dt>
<dd class="clearfix"> DUF4200; Domain of unknown function (DUF4200)</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=293786">sd00045</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">995</span><span class="cddto">1021</span></dt>
<dd class="clearfix"> ANK; ANK repeat [structural motif]</dd>
</dl>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=298833">cl09111</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">276</span><span class="cddto">386</span></dt>
<dd class="clearfix"> Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...</dd>
</dl>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_017021116.2">XM_017021116.2</a><a href="/protein/XP_016876605.1">XP_016876605.1</a>  apoptosis-stimulating of p53 protein 1 isoform X3</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A3B3ISJ2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">A0A3B3ISJ2</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047431171.1">XM_047431171.1</a><a href="/protein/XP_047287127.1">XP_047287127.1</a>  apoptosis-stimulating of p53 protein 1 isoform X5</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A3B3ISJ2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">A0A3B3ISJ2</a>
</dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000497343.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">ENSP00000497343.1</a>, <a href="http://www.ensembl.org/id/ENST00000647748.1" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">ENST00000647748.1</a></dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_017021117.2">XM_017021117.2</a><a href="/protein/XP_016876606.1">XP_016876606.1</a>  apoptosis-stimulating of p53 protein 1 isoform X4</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A3B3ISJ2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">A0A3B3ISJ2</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_047431170.1">XM_047431170.1</a><a href="/protein/XP_047287126.1">XP_047287126.1</a>  apoptosis-stimulating of p53 protein 1 isoform X4</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A3B3ISJ2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">A0A3B3ISJ2</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_017021119.2">XM_017021119.2</a><a href="/protein/XP_016876608.1">XP_016876608.1</a>  apoptosis-stimulating of p53 protein 1 isoform X7</p>
<dl></dl>
</li>
<li>
<p><a href="/nuccore/XM_047431172.1">XM_047431172.1</a><a href="/protein/XP_047287128.1">XP_047287128.1</a>  apoptosis-stimulating of p53 protein 1 isoform X6</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A3B3ISJ2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">A0A3B3ISJ2</a>
</dd>
</dl>
</li>
</ol>
<h4 id="rna-p141739408">RNA</h4>
<ol>
<li>
<p><a href="/nuccore/XR_007063997.1">XR_007063997.1</a> RNA Sequence </p>
<dl></dl>
</li>
<li>
<p><a href="/nuccore/XR_001750206.3">XR_001750206.3</a> RNA Sequence </p>
<dl></dl>
</li>
<li>
<p><a href="/nuccore/XR_001750205.3">XR_001750205.3</a> RNA Sequence </p>
<dl></dl>
</li>
<li>
<p><a href="/nuccore/XR_001750204.3">XR_001750204.3</a> RNA Sequence </p>
<dl></dl>
</li>
</ol>
<h3 id="refseq-sequencedescription-p69141056">Alternate T2T-CHM13v2.0</h3>
<h4 id="genomic-p69141056">Genomic </h4>
<ol>
<li>
<p>NC_060938.1 Alternate T2T-CHM13v2.0</p>
<dl>
<dt>Range</dt>
<dd class="rs-range">
<span>97969263..98085448 complement</span>
</dd>
<dt>Download</dt>
<dd><a href="/nuccore/NC_060938.1?from=97969263&amp;to=98085448&amp;report=genbank&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=NC_060938.1?from=97969263&amp;to=98085448&amp;report=genbank&amp;strand=true">GenBank</a>, <a href="/nuccore/NC_060938.1?from=97969263&amp;to=98085448&amp;report=fasta&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=NC_060938.1?from=97969263&amp;to=98085448&amp;report=fasta&amp;strand=true">FASTA</a>, <a href="/nuccore/NC_060938.1?from=97951834&amp;to=98102875&amp;report=graph&amp;content=5&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=NC_060938.1?from=97951834&amp;to=98102875&amp;report=graph&amp;content=5&amp;strand=true">Sequence Viewer (Graphics)</a></dd>
</dl>
</li>
</ol>
<h4 id="mrnaandproteins-p74641520">mRNA and Protein(s) </h4>
<ol>
<li>
<p><a href="/nuccore/XM_054375720.1">XM_054375720.1</a><a href="/protein/XP_054231695.1">XP_054231695.1</a>  apoptosis-stimulating of p53 protein 1 isoform X2</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A3B3ISJ2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">A0A3B3ISJ2</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054375718.1">XM_054375718.1</a><a href="/protein/XP_054231693.1">XP_054231693.1</a>  apoptosis-stimulating of p53 protein 1 isoform X1</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A3B3ISJ2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">A0A3B3ISJ2</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054375721.1">XM_054375721.1</a><a href="/protein/XP_054231696.1">XP_054231696.1</a>  apoptosis-stimulating of p53 protein 1 isoform X3</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A3B3ISJ2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">A0A3B3ISJ2</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054375725.1">XM_054375725.1</a><a href="/protein/XP_054231700.1">XP_054231700.1</a>  apoptosis-stimulating of p53 protein 1 isoform X5</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A3B3ISJ2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">A0A3B3ISJ2</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054375722.1">XM_054375722.1</a><a href="/protein/XP_054231697.1">XP_054231697.1</a>  apoptosis-stimulating of p53 protein 1 isoform X4</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A3B3ISJ2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">A0A3B3ISJ2</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054375723.1">XM_054375723.1</a><a href="/protein/XP_054231698.1">XP_054231698.1</a>  apoptosis-stimulating of p53 protein 1 isoform X4</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A3B3ISJ2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">A0A3B3ISJ2</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054375727.1">XM_054375727.1</a><a href="/protein/XP_054231702.1">XP_054231702.1</a>  apoptosis-stimulating of p53 protein 1 isoform X7</p>
<dl></dl>
</li>
<li>
<p><a href="/nuccore/XM_054375724.1">XM_054375724.1</a><a href="/protein/XP_054231699.1">XP_054231699.1</a>  apoptosis-stimulating of p53 protein 1 isoform X9</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A3B3ISJ2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">A0A3B3ISJ2</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054375719.1">XM_054375719.1</a><a href="/protein/XP_054231694.1">XP_054231694.1</a>  apoptosis-stimulating of p53 protein 1 isoform X8</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A3B3ISJ2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">A0A3B3ISJ2</a>
</dd>
</dl>
</li>
<li>
<p><a href="/nuccore/XM_054375726.1">XM_054375726.1</a><a href="/protein/XP_054231701.1">XP_054231701.1</a>  apoptosis-stimulating of p53 protein 1 isoform X6</p>
<dl>
<dt>UniProtKB/TrEMBL</dt>
<dd>
<a href="https://www.uniprot.org/uniprot/A0A3B3ISJ2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=23368&amp;nlmid=&amp;db=gene">A0A3B3ISJ2</a>
</dd>
</dl>
</li>
</ol>
</div>
</div>
</div>
<div class="rprt-section gene-related-sequences">
<section class="rprt-section-header" id="related-sequences">
<h2 id="header-related-sequences">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-related-sequences .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Related sequences</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Related_Sequences" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div>
<table id="proteinTblId" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/23368/data/related-sequences/',webserviceParams: 'p$l=Ajax', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
<thead>
<tr>
<th colspan="2" id="rs-nucleo">Nucleotide</th>
<th rowspan="2" id="rs-protein">Protein</th>
</tr>
<tr>
<th id="rs-heading">Heading</th>
<th id="rs-heading-acc">Accession and Version</th>
</tr>
</thead>
<tbody></tbody>
</table>
<table id="proteinTblId" class="jig-ncbigrid" data-jigconfig="isPageable:true, pageSize:25">
<thead>
<tr>
<th class="proteinTblTh" rowspan="2" id="rs-prot-acc">Protein Accession</th>
<th class="proteinTblTh" colspan="2" id="rs-link">Links</th>
</tr>
<tr>
<th id="rs-genepept">GenPept Link</th>
<th id="rs-uniprot">UniProtKB Link</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="rs-prot-acc">Q96KQ4.3</td>
<td headers="rs-link rs-genepept">
<a href="/protein/296439434" ref="ordinalpos=1&amp;ncbi_uid=23368&amp;link_uid=296439434">GenPept</a>
</td>
<td>
<a href="https://www.uniprot.org/uniprot/Q96KQ4">UniProtKB/Swiss-Prot:Q96KQ4</a>
</td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
<div class="rprt-section gene-additional-links">
<section class="rprt-section-header" id="additional-links"><h2 id="header-additional-links"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-additional-links .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Additional links</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Additional_Links" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
<div class="rprt-section-body" style="">
<h3 class="withnote" id="genelinkout">
<a class="jig-ncbitoggler">Gene LinkOut</a>
</h3><div>
<p>The following <a href="https://www.ncbi.nlm.nih.gov/projects/linkout/index.html">LinkOut</a> resources are supplied by external providers. These providers are responsible for maintaining the links. </p>
<div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Chemical Information</span>
</a>
<ul>
<li><span class="free-rsc"></span>Interologous Interaction Database</li>
<ul>
<li>
<a target="_blank" href="http://ophid.utoronto.ca/redirect/ncbi/human?proteins=23368" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7911">
<span>Interologous Interaction Database</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>MilliporeSigma</li>
<ul>
<li>
<a target="_blank" href="https://www.sigmaaldrich.com/catalog/genes/PPP1R13B?lang=en&amp;region=US" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9978">
<span>Ppp1r13b products</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Molecular Biology Databases</span>
</a>
<ul>
<li><span class="free-rsc"></span>Bgee database</li>
<ul>
<li>
<a target="_blank" href="https://www.bgee.org/gene/ENSG00000088808" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10418">
<span>PPP1R13B gene expression</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>BioGPS</li>
<ul>
<li>
<a target="_blank" href="http://biogps.org/gene/23368/" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5059">
<span>BioGPS</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>BioGRID Open Repository of CRISPR Screens (ORCS)</li>
<ul>
<li>
<a target="_blank" href="https://orcs.thebiogrid.org/Gene/23368" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10164">
<span>BioGRID CRISPR Screen Phenotypes (16 hits/1365 screens)</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>CTD: Comparative Toxicogenomics Database</li>
<ul>
<li>
<a target="_blank" href="http://ctdbase.org/detail.go?type=gene&amp;acc=23368" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7845">
<span>CTD: Comparative Toxicogenomics Database - PPP1R13B</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Eukaryotic Promoter Database</li>
<ul>
<li>
<a target="_blank" href="http://epd.vital-it.ch/cgi-bin/get_doc?db=hgEpdNew&amp;format=genome&amp;entry=PPP1R13B_1" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9624">
<span>PPP1R13B_1</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>GlyGen glycoinformatics resource</li>
<ul>
<li>
<a target="_blank" href="https://glygen.org/protein/Q96KQ4" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10227">
<span>GlyGen glycoinformatics resource</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Human eFP Browser</li>
<ul>
<li>
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Circulatory_Respiratory&amp;modeInput=Absolute&amp;primaryGene=23368" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8875">
<span>Human eFP Browser</span>
</a>
</li>
<li>
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Skeletal_Immune_Digestive&amp;modeInput=Absolute&amp;primaryGene=23368" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8875">
<span>Human eFP Browser</span>
</a>
</li>
<li>
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Reproductive&amp;modeInput=Absolute&amp;primaryGene=23368" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8875">
<span>Human eFP Browser</span>
</a>
</li>
</ul>
<li>Ingenuity Pathways Analysis</li>
<ul>
<li>
<a target="_blank" href="http://partnersolution.ingenuity.com/?cid=97ae3f91eab87a&amp;p1=Entrez&amp;p2=GV&amp;s=&amp;ipaUri=%2Fpa%2Fapi%2Fv2%2Fgeneview%3Fapplicationname%3DEntrez%26geneId%3D23368%26geneidtype%3Dentrezgene" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5628">
<span>Ingenuity Pathways Analysis</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>InnateDB</li>
<ul>
<li>
<a target="_blank" href="http://www.innatedb.com/getGeneCard.do?id=22173" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7894">
<span>InnateDB</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>InterMine</li>
<ul>
<li>
<a target="_blank" href="https://www.humanmine.org/humanmine/search?keyword=ENSG00000088808" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9169">
<span>InterMine</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Kyoto Encyclopedia of Genes and Genomes</li>
<ul>
<li>
<a target="_blank" href="http://www.genome.jp/dbget-bin/www_bget?hsa:23368" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5174">
<span>Kyoto Encyclopedia of Genes and Genomes</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>OMA Browser: Orthologous MAtrix</li>
<ul>
<li>
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN21500/" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9822">
<span>OMA Browser: Orthologous MAtrix</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>OrthoDB catalog of orthologs</li>
<ul>
<li>
<a target="_blank" href="https://www.orthodb.org/?ncbi=23368" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8178">
<span>Orthologs</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>PhosphoSitePlus</li>
<ul>
<li>
<a target="_blank" href="https://www.phosphosite.org/entrezGeneIdAction.action?id=23368" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7987">
<span>PhosphoSitePlus® - comprehensive post-translational modification resource</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>The Gene Wiki</li>
<ul>
<li>
<a target="_blank" href="https://en.wikipedia.org/wiki/PPP1R13B" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=6933">
<span>The Gene Wiki</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>The Weizmann Institute of Science GeneCards and MalaCards databases</li>
<ul>
<li>
<a target="_blank" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=PPP1R13B" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8598">
<span>GeneCard for PPP1R13B</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Research Materials</span>
</a>
<ul>
<li><span class="order-rsc"></span>Addgene Non-profit plasmid repository</li>
<ul>
<li>
<a target="_blank" href="https://addgene.org//browse/gene/23368" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5304">
<span>Get Plasmids - Addgene</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>Bio-Techne</li>
<ul>
<li>
<a target="_blank" href="https://www.bio-techne.com/t/aspp1/proteins-enzymes?utm_source=linkout&amp;utm_medium=referral&amp;utm_campaign=product&amp;utm_term=proteins" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8242">
<span>ASPP1 Proteins</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.bio-techne.com/t/aspp1/antibodies?utm_source=linkout&amp;utm_medium=referral&amp;utm_campaign=product&amp;utm_term=antibodies" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8242">
<span>ASPP1 Antibodies</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.bio-techne.com/t/aspp1/lysates?utm_source=linkout&amp;utm_medium=referral&amp;utm_campaign=product&amp;utm_term=lysates" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8242">
<span>ASPP1 Lysates</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>Creative Biogene</li>
<ul>
<li>
<a target="_blank" href="https://www.creative-biogene.com/genesearch/Ppp1r13b.html" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10094">
<span>protein phosphatase 1, regulatory subunit 13B</span>
</a>
</li>
</ul>
<li>ExactAntigen/Labome</li>
<ul>
<li>
<a target="_blank" href="https://www.labome.com/gene/human/ASPP1-antibody.html" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5753">
<span>reagents</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>GenScript latest version of gene cDNA ORF Clone</li>
<ul>
<li>
<a target="_blank" href="http://www.genscript.com/gene/23368" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8012">
<span>GenScript latest version of gene cDNA ORF Clone</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>GeneCopoeia Inc.</li>
<ul>
<li>
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=26&amp;field=5&amp;key=23368" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7255">
<span>Order TALEN/CRISPR clones</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?tax_id=9606&amp;field=5&amp;prt=16&amp;key=23368" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7255">
<span>Order miRNA target clones</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=1&amp;field=5&amp;key=23368" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7255">
<span>Order full-length ORF clone</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>GeneTex Inc</li>
<ul>
<li>
<a target="_blank" href="https://www.genetex.com/Product/Search?geneid=23368&amp;type=01&amp;page=1" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8117">
<span>Find Quality Antibodies</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>Kazusa DNA Research Institute</li>
<ul>
<li>
<a target="_blank" href="http://www.kazusa.or.jp/kop/dsearch/symsearch.cgi?keyword=PPP1R13B;" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=3267">
<span>Kazusa DNA Research Institute</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>OriGene</li>
<ul>
<li>
<a target="_blank" href="https://www.origene.com/search?q=PPP1R13B" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7994">
<span>Order PPP1R13B cDNA clone/Protein/Antibody/RNAi</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Tools</span>
</a>
<ul>
<li><span class="free-rsc"></span>GeneMANIA</li>
<ul>
<li>
<a target="_blank" href="http://genemania.org/link?o=9606&amp;g=23368" ref="itool=Gene_FullReport&amp;uid=23368&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7529">
<span>GeneMANIA</span>
</a>
</li>
</ul>
</ul>
</div>
</div>
</div>
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</div>
</div>
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<!-- sidebar close/hide button-->
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<h2 class="offscreen_noflow">Supplemental Content</h2>
<div id="gene-sidebar">
<div>
<div class="portlet brieflink dis-table-of-contents">
<div class="portlet_head">
<div class="portlet_title">
<h3>Table of contents</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_TableOfContents" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter"></a>
</div>
<div class="portlet_content">
<ul>
<li class="">
<a href="#summary">Summary</a>
</li>
<li class="">
<a href="#genomic-context">Genomic context</a>
</li>
<li class="">
<a href="#genomic-regions-transcripts-products">Genomic regions, transcripts, and products</a>
</li>
<li class="">
<a href="#gene-expression">Expression</a>
</li>
<li class="">
<a href="#bibliography">Bibliography</a>
</li>
<li class="">
<a href="#phenotypes">Phenotypes</a>
</li>
<li class="">
<a href="#variation">Variation</a>
</li>
<li class="">
<a href="#HIV-1-interactions">HIV-1 interactions</a>
</li>
<li class="">
<a href="#pathways">Pathways from PubChem</a>
</li>
<li class="">
<a href="#interactions">Interactions</a>
</li>
<li class="">
<a href="#general-gene-info">General gene information</a>
<div class="subsection-links"><a href="#gene-markers">Markers</a>, <a href="#CloneNames">Clone Names</a>, <a href="#homology">Homology</a>, <a href="#gene-ontology">Gene Ontology</a></div>
</li>
<li class="">
<a href="#general-protein-info">General protein information</a>
</li>
<li class="">
<a href="#reference-sequences">NCBI Reference Sequences (RefSeq)</a>
</li>
<li class="">
<a href="#related-sequences">Related sequences</a>
</li>
<li class="">
<a href="#additional-links">Additional links</a>
</li>
</ul>
</div>
</div>
<div class="portlet brieflink dis-genomesbrowser brieflink dis-genomesbrowser">
<div class="portlet_head">
<div class="portlet_title">
<h3>Genome Browsers</h3>
</div>
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</li>
</ul>
</div>
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<div class="portlet dis-related-info brieflink">
<div class="portlet_head">
<div class="portlet_title">
<h3>Related information</h3>
</div>
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</div>
<div class="portlet_content DiscoveryDbLinks">
<ul>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/clone/order/gene/23368" ref="log$=recordlinks">Order cDNA clone</a>
<div class="brieflinkpop offscreen_noflow">Order cDNA clone</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/structure?LinkName=gene_structure&amp;from_uid=23368" ref="log$=recordlinks">3D structures</a>
<div class="brieflinkpop offscreen_noflow">3D structure of a gene</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_alltarget_list&amp;from_uid=23368" ref="log$=recordlinks">BioAssay by Target (List)</a>
<div class="brieflinkpop offscreen_noflow">BioAssays related to the gene by protein target or RNAi target</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_target&amp;from_uid=23368" ref="log$=recordlinks">BioAssay, by Gene target</a>
<div class="brieflinkpop offscreen_noflow">PubChem BioAssays done on the Gene target</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_rnai&amp;from_uid=23368" ref="log$=recordlinks">BioAssays, RNAi Target, Tested</a>
<div class="brieflinkpop offscreen_noflow">BioAssays that contain the gene as the target of a RNAi reagent</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/bioproject?LinkName=gene_bioproject&amp;from_uid=23368" ref="log$=recordlinks">BioProjects</a>
<div class="brieflinkpop offscreen_noflow">BioProjects related to a gene</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/biosystems?LinkName=gene_biosystems&amp;from_uid=23368" ref="log$=recordlinks">BioSystems</a>
<div class="brieflinkpop offscreen_noflow">BioSystems</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/CCDS/CcdsBrowse.cgi?REQUEST=GENEID&amp;DATA=23368" ref="log$=recordlinks">CCDS</a>
<div class="brieflinkpop offscreen_noflow">Link to CCDS</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar&amp;from_uid=23368" ref="log$=recordlinks">ClinVar</a>
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/cdd?LinkName=gene_cdd&amp;from_uid=23368" ref="log$=recordlinks">Conserved Domains</a>
<div class="brieflinkpop offscreen_noflow">Related CDD</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/dbvar?LinkName=gene_dbvar&amp;from_uid=23368" ref="log$=recordlinks">dbVar</a>
<div class="brieflinkpop offscreen_noflow">Link from Gene to dbVar</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc&amp;from_uid=23368" ref="log$=recordlinks">Full text in PMC</a>
<div class="brieflinkpop offscreen_noflow">PMC links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc_nucleotide&amp;from_uid=23368" ref="log$=recordlinks">Full text in PMC_nucleotide</a>
<div class="brieflinkpop offscreen_noflow">Full text in PubMedCentral identified from shared sequence links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/sparcle?LinkName=gene_sparcle&amp;from_uid=23368" ref="log$=recordlinks">Functional Class</a>
<div class="brieflinkpop offscreen_noflow">Functional class of the sequence domain architecture</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_neighbors&amp;from_uid=23368" ref="log$=recordlinks">Gene neighbors</a>
<div class="brieflinkpop offscreen_noflow">Overlapping genes and two nearest non-overlapping genes on either side</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_h3k4me3&amp;from_uid=23368" ref="log$=recordlinks">Genes with a similar H3K4me3 profile</a>
<div class="brieflinkpop offscreen_noflow">Genes with a similar profile of promoter-activating H3K4me3 modifications across several tissue types</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/genome?LinkName=gene_genome&amp;from_uid=23368" ref="log$=recordlinks">Genome</a>
<div class="brieflinkpop offscreen_noflow">Related Genome</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/geoprofiles?LinkName=gene_geoprofiles&amp;from_uid=23368" ref="log$=recordlinks">GEO Profiles</a>
<div class="brieflinkpop offscreen_noflow">Related GEO</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gtr/tests/?term=23368[geneid]" ref="log$=recordlinks">GTR</a>
<div class="brieflinkpop offscreen_noflow">Tests for this gene in the NIH Genetic Testing Registry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/homologene?LinkName=gene_homologene&amp;from_uid=23368" ref="log$=recordlinks">HomoloGene</a>
<div class="brieflinkpop offscreen_noflow">Related HomoloGene</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore&amp;from_uid=23368" ref="log$=recordlinks">Nucleotide</a>
<div class="brieflinkpop offscreen_noflow">Link to related Nucleotide entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/omim?LinkName=gene_omim&amp;from_uid=23368" ref="log$=recordlinks">OMIM</a>
<div class="brieflinkpop offscreen_noflow">Link to related OMIM entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/probe?LinkName=gene_probe&amp;from_uid=23368" ref="log$=recordlinks">Probe</a>
<div class="brieflinkpop offscreen_noflow">Related Probe entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein&amp;from_uid=23368" ref="log$=recordlinks">Protein</a>
<div class="brieflinkpop offscreen_noflow">Link to related protein entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pccompound?LinkName=gene_pccompound&amp;from_uid=23368" ref="log$=recordlinks">PubChem Compound</a>
<div class="brieflinkpop offscreen_noflow">PubChem Compounds</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcsubstance?LinkName=gene_pcsubstance&amp;from_uid=23368" ref="log$=recordlinks">PubChem Substance</a>
<div class="brieflinkpop offscreen_noflow">PubChem Substances</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed&amp;from_uid=23368" ref="log$=recordlinks">PubMed</a>
<div class="brieflinkpop offscreen_noflow">Link to related PubMed entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_rif&amp;from_uid=23368" ref="log$=recordlinks">PubMed (GeneRIF)</a>
<div class="brieflinkpop offscreen_noflow">Link to related PubMed article from GeneRIFs</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_citedinomim&amp;from_uid=23368" ref="log$=recordlinks">PubMed (OMIM)</a>
<div class="brieflinkpop offscreen_noflow">Gene links to PubMed derived from omim_pubmed_cited links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_pmc_nucleotide&amp;from_uid=23368" ref="log$=recordlinks">PubMed(nucleotide/PMC)</a>
<div class="brieflinkpop offscreen_noflow">Citations in PubMed identified from shared sequence and PMC links.</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein_refseq&amp;from_uid=23368" ref="log$=recordlinks">RefSeq Proteins</a>
<div class="brieflinkpop offscreen_noflow">Link to Protein RefSeqs</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore_refseqrna&amp;from_uid=23368" ref="log$=recordlinks">RefSeq RNAs</a>
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeq RNAs</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/nuccore/1024357481?report=graph" ref="log$=recordlinks">RefSeqGene</a>
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeqGenes</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/snp?LinkName=gene_snp&amp;from_uid=23368" ref="log$=recordlinks">SNP</a>
<div class="brieflinkpop offscreen_noflow">Related SNP records</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/taxonomy?LinkName=gene_taxonomy&amp;from_uid=23368" ref="log$=recordlinks">Taxonomy</a>
<div class="brieflinkpop offscreen_noflow">Link to related taxonomy entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/variation/view/?q=23368[geneid]" ref="log$=recordlinks">Variation Viewer</a>
<div class="brieflinkpop offscreen_noflow">Related Variants</div>
</li>
</ul>
</div>
</div>
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<div class="portlet_head">
<div class="portlet_title">
<h3>Links to other resources</h3>
</div>
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</div>
<div class="portlet_content">
<ul>
<li>
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:14950">HGNC</a>
</li>
<li>
<a href="http://www.ensembl.org/id/ENSG00000088808">Ensembl</a>
</li>
<li>
<a href="https://www.alliancegenome.org/gene/HGNC:14950">AllianceGenome</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=geneid&amp;org=9606&amp;l=23368">AceView</a>
</li>
<li>
<a href="http://zearth.kazusa.or.jp/huge/gfpage/KIAA0771">HUGE</a>
</li>
<li>
<a href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&amp;position=NM_015316">UCSC</a>
</li>
<li>
<a href="https://phgkb.cdc.gov/PHGKB/huGEPedia.action?firstQuery=PPP1R13B&amp;geneID=23368&amp;typeOption=gene&amp;which=2&amp;pubOrderType=pubD&amp;typeSubmit=GO&amp;check=y">HuGE Navigator</a>
</li>
<li>
<a href="http://www.genome.jp/dbget-bin/www_bget?hsa:23368">KEGG</a>
</li>
</ul>
</div>
</div>
<div class="portlet brieflink dis-general-info">
<div class="portlet_head">
<div class="portlet_title">
<h3>General information</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_GeneralInfo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter"></a>
</div>
<div class="portlet_content">
<ul>
<li>
<a href="/pmc/?term=PMC4383897+OR+PMC3013746+OR+PMC1761442+OR+PMC539985">About Gene</a>
</li>
<li>
<a href="/books/NBK3840">FAQ</a>
</li>
<li>
<a href="https://ftp.ncbi.nlm.nih.gov/gene/">FTP site</a>
</li>
<li>
<a href="/books/NBK3841/">Help</a>
</li>
<li>
<a href="/books/NBK3842/">My NCBI help</a>
</li>
<li>
<a href="/books/NBK21085/">NCBI Handbook</a>
</li>
<li>
<a href="/gene/statistics/">Statistics</a>
</li>
</ul>
</div>
</div>
<div class="portlet brieflink dis-related-sites">
<div class="portlet_head">
<div class="portlet_title">
<h3>Related sites</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedSites.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_RelatedSites" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedSites.Shutter"></a>
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<div class="portlet_content">
<ul>
<li>
<a href="https://www.ncbi.nlm.nih.gov/BLAST">BLAST</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/genome">Genome</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/bioproject">BioProject</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/genome/gdv/">Genome Data Viewer</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/geo">GEO</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/omim">OMIM</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/probe">Probe</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/RefSeq">RefSeq</a>
</li>
</ul>
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<a href="https://support.ncbi.nlm.nih.gov/ics/support/ticketnewwizard.asp?style=classic&amp;deptID=28049">Contact Help Desk</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/RefSeq/update.cgi?geneid=23368&amp;symbol=PPP1R13B">Submit Correction</a>
</li>
<li>
<a href="/gene/submit-generif?geneId=23368&amp;sym=PPP1R13B&amp;name=protein phosphatase 1 regulatory subunit 13B&amp;org=Homo sapiens">Submit GeneRIF</a>
</li>
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<h3>Subscription</h3>
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<a href="https://www.ncbi.nlm.nih.gov/mailman/listinfo/refseq-announce">RefSeq</a>
</li>
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<ul id="activity">
<li class="ra_rcd ralinkpopper two_line">
<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67c9e482b15b832ebc24d97c">PPP1R13B protein phosphatase 1 regulatory subunit 13B [Homo sapiens]</a>
<div class="ralinkpop offscreen_noflow">PPP1R13B protein phosphatase 1 regulatory subunit 13B [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:23368</div></div>
<div class="tertiary">Gene</div>
</li>
<li class="ra_rcd ralinkpopper two_line">
<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=2" href="/portal/utils/pageresolver.fcgi?recordid=67c9e48184f3725e59529c5b">apoptosis-stimulating of p53 protein 1 [Homo sapiens]</a>
<div class="ralinkpop offscreen_noflow">apoptosis-stimulating of p53 protein 1 [Homo sapiens]<div class="brieflinkpopdesc">gi|121114287|ref|NP_056131.2|</div></div>
<div class="tertiary">Protein</div>
</li>
<li class="ra_rcd ralinkpopper two_line">
<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=3" href="/portal/utils/pageresolver.fcgi?recordid=67c9e47fa68b6b5afc8909f6">PPP1CB protein phosphatase 1 catalytic subunit beta [Homo sapiens]</a>
<div class="ralinkpop offscreen_noflow">PPP1CB protein phosphatase 1 catalytic subunit beta [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:5500</div></div>
<div class="tertiary">Gene</div>
</li>
<li class="ra_rcd ralinkpopper two_line">
<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=4" href="/portal/utils/pageresolver.fcgi?recordid=67c9e47df4a390645e532089">serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform 1 [Homo ...</a>
<div class="ralinkpop offscreen_noflow">serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform 1 [Homo sapiens]<div class="brieflinkpopdesc">gi|4506005|ref|NP_002700.1|</div></div>
<div class="tertiary">Protein</div>
</li>
<li class="ra_rcd ralinkpopper two_line">
<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=5" href="/portal/utils/pageresolver.fcgi?recordid=67c9e47cb15b832ebc24afd7">PPIB peptidylprolyl isomerase B [Homo sapiens]</a>
<div class="ralinkpop offscreen_noflow">PPIB peptidylprolyl isomerase B [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:5479</div></div>
<div class="tertiary">Gene</div>
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