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3436 lines
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269 KiB
XML
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<h1 class="res_name"><a href="/gene/">Gene</a></h1>
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<h2 class="res_tagline">Genes and mapped phenotypes</h2>
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<div class="search"><div class="search_form"><label for="database" class="offscreen_noflow">Search database</label><select id="database"><optgroup label="Recent"><option value="books">Books</option><option value="pubmed">PubMed</option><option value="clinvar">ClinVar</option><option value="medgen" class="last">MedGen</option></optgroup><optgroup label="All"><option value="gquery">All Databases</option><option value="assembly" data-ac_dict="assembly">Assembly</option><option value="biocollections">Biocollections</option><option value="bioproject">BioProject</option><option value="biosample">BioSample</option><option value="books">Books</option><option value="clinvar">ClinVar</option><option value="cdd">Conserved Domains</option><option value="gap">dbGaP</option><option value="dbvar">dbVar</option><option value="gene" selected="selected" data-ac_dict="gene">Gene</option><option value="genome" data-ac_dict="genome">Genome</option><option value="gds">GEO DataSets</option><option value="geoprofiles">GEO Profiles</option><option value="gtr">GTR</option><option value="ipg">Identical Protein Groups</option><option value="medgen">MedGen</option><option value="mesh">MeSH</option><option value="nlmcatalog">NLM Catalog</option><option value="nuccore" data-ac_dict="nuccore">Nucleotide</option><option value="omim">OMIM</option><option value="pmc">PMC</option><option value="protein" data-ac_dict="protein">Protein</option><option value="proteinclusters">Protein Clusters</option><option value="protfam">Protein Family Models</option><option value="pcassay">PubChem BioAssay</option><option value="pccompound">PubChem Compound</option><option value="pcsubstance">PubChem Substance</option><option value="pubmed">PubMed</option><option value="snp">SNP</option><option value="sra">SRA</option><option value="structure">Structure</option><option value="taxonomy">Taxonomy</option><option value="toolkit">ToolKit</option><option value="toolkitall">ToolKitAll</option><option value="toolkitbookgh">ToolKitBookgh</option></optgroup></select><div class="nowrap"><label for="term" class="offscreen_noflow" accesskey="/">Search term</label><div class="nowrap"><input type="text" name="term" id="term" title="Search Gene. Use up and down arrows to choose an item from the autocomplete." value="" class="jig-ncbiclearbutton jig-ncbiautocomplete" data-jigconfig="dictionary:'gene',disableUrl:'NcbiSearchBarAutoComplCtrl'" autocomplete="off" data-sbconfig="ds:'no',pjs:'yes',afs:'yes'" /></div><button id="search" type="submit" class="button_search nowrap" cmd="go">Search</button></div></div><ul class="searchlinks inline_list"><set></set><li><a href="/gene/advanced">Advanced</a></li><li class="help"><a id="help" class="jig-ncbihelpwindow" target="ncbihelp" name="help" href="/books/NBK3841/">Help</a></li></ul></div>
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<input name="EntrezSystem2.PEntrez.Gene.Gene_PageController.PreviousPageName" sid="1" type="hidden" value="results" />
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<h2 class="offscreen_noflow">Result Filters</h2>
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<div class="facet_cont" data-db="gene" data-default_grps="fg_gene-sources,fg_categories,fg_sequence-content,fg_status" data-sd="db:'gene',op:'select',term:'',qk:'21603',linkname:'',idsfromresult:'11262',extra:''"><ul class="facet" data-filter_id="gene-sources" id="_gene-sources"><li class="filter_grp "><div class="clearfix"><h3>Gene sources</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="genomic">Genomic</a></li></ul></li></ul><ul class="facet" data-filter_id="categories" id="_categories"><li class="filter_grp "><div class="clearfix"><h3>Categories</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="alt-splicing">Alternatively spliced</a></li><li class="fil_val"><a href="#" data-value_id="annotated-genes">Annotated genes</a></li><li class="fil_val"><a href="#" data-value_id="gene-type-protein-coding">Protein-coding</a></li></ul></li></ul><ul class="facet" data-filter_id="sequence-content" id="_sequence-content"><li class="filter_grp "><div class="clearfix"><h3>Sequence content</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="seq-ccds">CCDS</a></li><li class="fil_val"><a href="#" data-value_id="seq-ensembl">Ensembl</a></li><li class="fil_val"><a href="#" data-value_id="refseq">RefSeq</a></li><li class="fil_val"><a href="#" data-value_id="seq-refseqgene">RefSeqGene</a></li></ul></li></ul><ul class="facet" data-filter_id="status" id="_status"><li class="filter_grp "><div class="clearfix"><h3>Status</h3><a href="#" data-value_id="" class="clear clear_show">Clear</a></div><ul><li class="fil_val selected"><a href="#" data-value_id="current-only">Current</a><span class="fcount">(1)</span></li></ul></li></ul><div id="chr-location-facet-wrapper" data-bid="MCID_67d433524f3d5e000d4d607e" data-hid="MCID_67d2a666fe1ad803e8633767" data-qky="21603" class="disabled" style="display:none"><ul class="facet" data-filter_id="chromosomal-region" id="_chromosomal-region" data-of="yes"><li class="filter_grp of_grp"><div class="clearfix"><h3>Chromosome locations</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><a id="facet_ofchromosomal-region" href="#facet_of_divchromosomal-region" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'middle left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '375px'" data-value_id="fetch_more">more...</a><div id="facet_of_divchromosomal-region" style="display:none;" class="of_popup"><h4>Chromosome locations</h4><label for="organism-filter" style="width:100%;margin-bottom:.2em;" class="">Select an organism by typing or scrolling</label><input type="text" placeholder="Enter text to narrow down the list" id="organism-filter" style="width:98%;" autocomplete="off" /><br /><div id="chr-region-tax-list"><select id="of_chromosomal-region" size="9" class="chr-region-tax-list" style="width:100%;"></select></div><div id="chr-location-info-ctrl" data-disabled="disabled"><div class="chr-field"><label for="chr-name">Chromosome</label><br /><select id="chr-name" class="chr-field" disabled="disabled"></select></div><div class="chr-field"><label for="chr-from">From</label><br /><input type="text" name="chr-from" id="chr-from" disabled="disabled" class="chr-field" /></div><div class="chr-field"><label for="chr-to">To</label><br /><input type="text" name="chr-to" id="chr-to" disabled="disabled" class="chr-field" /></div></div><div class="actions clearfix"><button class="jig-ncbibutton of_add apply-chr" data-jigconfig="'color': 'ui-ncbibutton-blue'">Apply</button></div></div></ul></li></ul></div><ul class="facet facet_reset"><li><a href="#" data-value_id="reset">Clear all</a></li></ul><ul class="facet_tools"><li><a id="more_filter_groups_link" href="#more_filter_groups" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'top left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '180px'">
|
||
Show additional filters</a></li><div id="more_filter_groups" style="display:none;" class="facets_dialog"><button class="ui-ncbipopper-close-button ui-ncbipopper-close-button-generated ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-blue" generated="true" role="button" aria-disabled="false"><span class="ui-button-text">x</span></button><h4>Additional filters</h4><ul class="filter_groups_more facet"><li><input type="checkbox" id="fg_gene-sources" /><label for="fg_gene-sources">Gene sources</label></li><li><input type="checkbox" id="fg_categories" /><label for="fg_categories">Categories</label></li><li><input type="checkbox" id="fg_sequence-content" /><label for="fg_sequence-content">Sequence content</label></li><li><input type="checkbox" id="fg_status" /><label for="fg_status">Status</label></li><li><input type="checkbox" id="fg_chromosomal-region" /><label for="fg_chromosomal-region">Chromosome locations</label></li><li><input id="fg_field_search" type="checkbox" /><label for="fg_field_search">Search fields</label></li></ul><div class="actions clearfix"><button class="filter_groups_more_apply jig-ncbibutton primary-action" id="filter_groups_apply" data-jigconfig="'color': 'ui-ncbibutton-blue'">Show</button></div></div></ul><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetsUrlFrag" sid="1" type="hidden" value="filters=current-only" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetSubmitted" sid="1" type="hidden" value="false" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.BMFacets" sid="1" type="hidden" value="" /></div>
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<span style="display: block; text-align: center;">S</span>
|
||
<span style="display: block; text-align: center;">I</span>
|
||
<span style="display: block; text-align: center;">D</span>
|
||
<span style="display: block; text-align: center;">E</span>
|
||
<span style="display: block; text-align: center;">B</span>
|
||
<span style="display: block; text-align: center;">A</span>
|
||
<span style="display: block; text-align: center;">R</span>
|
||
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|
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<div class="results_settings one_setting"><ul class="inline_list left display_settings"><li><a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Display" sid="0" href="#" class="jig-ncbipopper" data-jigconfig="triggerPosition : 'bottom center',destPosition : 'top center',destSelector : '#display_settings_menu_report', hasArrow : false,openEvent : 'click',closeEvent : 'click',isTriggerElementCloseClick: false,addCloseButton : false, groupName: 'entrez_pg'" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Display">Full Report<span href="#" class="tgt_dark"></span></a></li></ul><div id="display_settings_menu_report" class="disp_settings tabPopper"><fieldset class="format"><legend>Format</legend><ul class="column_list"><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="1" value="full_report" format="" id="full_report" checked="true" /><label for="full_report">Full Report</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="2" value="full_report" format="text" id="full_reporttext" /><label for="full_reporttext">Full Report (text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="3" value="expression" format="" id="expression" /><label for="expression">Expression</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="4" value="gene_table" format="" id="gene_table" /><label for="gene_table">Gene Table</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="5" value="gene_table" format="text" id="gene_tabletext" /><label for="gene_tabletext">Gene Table (text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="6" value="generif" format="" id="generif" /><label for="generif">GeneRIF</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="7" value="docsum" format="" id="docsum" /><label for="docsum">Summary</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="8" value="docsum" format="text" id="docsumtext" /><label for="docsumtext">Summary (text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="9" value="tabular" format="" id="tabular" /><label for="tabular">Tabular</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="10" value="tabular" format="text" id="tabulartext" /><label for="tabulartext">Tabular (text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="11" value="asn1" format="text" id="asn1text" /><label for="asn1text">ASN.1</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="12" value="xml" format="text" id="xmltext" /><label for="xmltext">XML</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="13" value="uilist" format="text" id="uilisttext" /><label for="uilisttext">UI List</label></li></ul></fieldset></div><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SetDisplay" sid="1" class="button_apply ncbipopper-close-button" style="display:none">Apply</button><h4 class="content_header send_to align_right jig-ncbipopper" id="sendto" data-jigconfig="triggerPosition:'bottom center', destPosition : 'top center',destSelector : '#send_to_menu', hasArrow : false, openEvent : 'click',closeEvent : 'click', isTriggerElementCloseClick: false, addCloseButton:true, groupName: 'entrez_pg', adjustFit:'none'"><a href="#" sourceContent="send_to_menu" class="tgt_dark">Send to:</a><script type="text/javascript">
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</script></h4><div id="send_to_menu" class="tabPopper send_to"><fieldset><legend>Choose Destination</legend><ul class="column_list"><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="1" value="File" id="dest_File" /><label for="dest_File">File</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="2" value="AddToClipboard" id="dest_AddToClipboard" /><label for="dest_AddToClipboard">Clipboard</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="3" value="AddToCollections" id="dest_AddToCollections" /><label for="dest_AddToCollections">Collections</label></li></ul></fieldset><div class="submenu file" id="submenu_File" style="display: none;"><p id="submenu_File_hint" class="hidden"></p><ul><li><label for="file_format">Format</label><select id="file_format" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FFormat" sid="1"><option value="full_report" format="text" selected="selected">Full Report (text)</option><option value="gene_table" format="text">Gene Table (text)</option><option value="docsum" format="text">Summary (text)</option><option value="tabular" format="text">Tabular (text)</option><option value="asn1" format="text">ASN.1</option><option value="xml" format="text">XML</option><option value="uilist" format="text">UI List</option></select></li></ul><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="1" class="button_apply file ncbipopper-close-button" type="submit" cmd="File">Create File</button></div><div class="submenu addtoclipboard" id="submenu_AddToClipboard" style="display: none;"><p id="submenu_AddToClipboard_hint" class="hidden"></p><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="2" class="button_apply clipboard ncbipopper-close-button" type="submit" cmd="AddToClipboard">Add to Clipboard</button></div><div class="submenu addtocollections" id="submenu_AddToCollections" style="display: none;"><p id="submenu_AddToCollections_hint" class="hidden"></p><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="3" class="button_apply collections ncbipopper-close-button" type="submit" cmd="AddToCollections">Add to Collections</button></div></div><div><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FileFormat" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastPresentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Presentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastPageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Sort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastSort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FileSort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Format" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastFormat" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevPageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevPresentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevSort" sid="1" type="hidden" value="" /><input type="hidden" id="coll_startindex" name="CollectionStartIndex" value="1" /></div></div>
|
||
<div>
|
||
|
||
|
||
|
||
</div>
|
||
<div class="">
|
||
<div><span id="result_sel" class="nowrap"></span><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_ResultsController.ResultCount" sid="1" type="hidden" id="resultcount" value="1" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_ResultsController.RunLastQuery" sid="1" type="hidden" /></div>
|
||
|
||
</div>
|
||
<div id="messagearea" class="empty">
|
||
|
||
|
||
|
||
|
||
</div>
|
||
<div class="rprt full-rprt">
|
||
<div>
|
||
<div class="rprt-header">
|
||
<input type="hidden" id="gene-tax-id" value="9606" />
|
||
<h1 class="title" id="gene-name"><span class="gn" style="padding-right:.5em;">SP140</span> SP140 nuclear body protein [ <em class="tax">Homo sapiens</em> (human)
|
||
]
|
||
</h1>
|
||
<span class="geneid">Gene ID: 11262, updated on
|
||
8-Mar-2025</span>
|
||
</div>
|
||
<div class="download-datasets">
|
||
<script type="text/javascript" src="https://cdnjs.cloudflare.com/ajax/libs/axios/0.23.0/axios.min.js"></script>
|
||
<h4 class="download-datasets-popper jig-ncbipopper" id="download-asm" style="align-self:start" data-jigconfig="triggerPosition:'bottom center', destPosition : 'top center',destSelector : '#download-datasets-popper-menu', hasArrow : false, openEvent : 'click',closeEvent : 'click', isTriggerElementCloseClick: false, groupName: 'entrez_pg', adjustFit:'none'" role="button" aria-expanded="false" aria-haspopup="true">
|
||
<svg alt="download" class="dlbtn-icon" x="0px" y="0px" width="15px" height="15px" viewBox="0 0 60 60" enable-background="new 0 0 60 60" xml:space="preserve">
|
||
<g>
|
||
<polygon points="48.75,36.25 48.75,48.75 11.25,48.75 11.25,36.25 5,36.25 5,55 55,55 55,36.25 "></polygon>
|
||
<polygon points="42.5,23.75 36.25,23.75 36.25,5 23.75,5 23.75,23.75 17.5,23.75 30,42.5 "></polygon>
|
||
</g>
|
||
</svg>
|
||
<a href="#">Download Datasets</a>
|
||
</h4>
|
||
<div id="download-datasets-popper-menu" style="display:none;">
|
||
<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-gene-seq-fasta" value="FASTA_GENE" checked="checked" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-gene-seq-fasta">Gene Sequences (FASTA)</label>
|
||
</div>
|
||
<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-transcript-seq-fasta" value="FASTA_RNA" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-transcript-seq-fasta">Transcript sequences (FASTA)</label>
|
||
</div>
|
||
<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-protein-seq-fasta" value="FASTA_PROTEIN" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-protein-seq-fasta">Protein sequences(FASTA)</label>
|
||
</div>
|
||
<p style="margin-left:5px;">In addition, your package will include a detailed data report in both TSV and JSONL formats.</p>
|
||
<div class="input-group">
|
||
<label for="datasets-download-file-name">File name</label>
|
||
<input type="text" id="datasets-download-file-name" placeholder="Name your file" style="padding:5px;" value="SP140_datasets.zip" />
|
||
</div>
|
||
<input type="hidden" id="download-datasets-base-url" value="https://api.ncbi.nlm.nih.gov/datasets/v2alpha/gene/download" />
|
||
<input type="hidden" id="gene-id-value" value="11262" />
|
||
<button id="datasets-download-submit" data-ga-action="click_begin_download" data-ga-label="download" class="jig-ncbibutton ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-gray" role="button">
|
||
<span class="ui-button-text">Download</span>
|
||
</button>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-body">
|
||
|
||
|
||
<div class="rprt-section gene-summary">
|
||
<section class="rprt-section-header" id="summary">
|
||
<h2 id="header-summary">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-summary .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Summary</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Summary_2" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div id="summaryDiv" class="section">
|
||
<dl id="summaryDl">
|
||
<dt class="noline"> Official
|
||
Symbol</dt>
|
||
<dd class="noline">SP140<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
|
||
<dt> Official
|
||
Full Name</dt>
|
||
<dd>SP140 nuclear body protein<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
|
||
<dt>Primary source</dt>
|
||
<dd>
|
||
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:17133" data-gblink-text="Ensembl">HGNC:HGNC:17133</a>
|
||
</dd>
|
||
<dt>See related</dt>
|
||
<dd>
|
||
<a href="http://www.ensembl.org/id/ENSG00000079263" data-gblink-text="Ensembl" class="genome-browser-link" data-genome-browser-link-sort="5" data-gb-url="http://www.ensembl.org/loc/ENSG00000079263">Ensembl:ENSG00000079263</a>
|
||
<a href="https://www.ncbi.nlm.nih.gov/omim/608602" data-gblink-text="Ensembl" ref="ordinalpos=1&ncbi_uid=11262&link_uid=608602">MIM:608602;</a>
|
||
<a href="https://www.alliancegenome.org/gene/HGNC:17133" data-gblink-text="Ensembl" ref="ordinalpos=1&ncbi_uid=11262&link_uid=HGNC:17133">AllianceGenome:HGNC:17133</a>
|
||
</dd>
|
||
<dt>Gene type</dt>
|
||
<dd>protein coding</dd>
|
||
<dt>RefSeq status</dt>
|
||
<dd>REVIEWED</dd>
|
||
<dt>Organism</dt>
|
||
<dd class="tax">
|
||
<a href="/Taxonomy/Browser/wwwtax.cgi?id=9606" ref="ordinalpos=1&ncbi_uid=11262&link_uid=9606">Homo sapiens</a>
|
||
</dd>
|
||
<dt>Lineage</dt>
|
||
<dd class="tax">Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo</dd>
|
||
<dt>Also known as</dt>
|
||
<dd>LYSP100; LYSP100-A; LYSP100-B</dd>
|
||
<dt>Summary</dt>
|
||
<dd>This gene encodes a member of the SP100 family of proteins, which are share common domains including an N-terminal homogeneously staining region domain followed by a SP100/autoimmune regulator/NucP41/P75/deformed epidermal autoregulatory factor domain, a plant homeobox zinc finger, and a bromodomain. The encoded protein is interferon-inducible and is expressed at high levels in the nuclei of leukocytes. Variants of this gene have been associated with multiple sclerosis, Crohn's disease, and chronic lymphocytic leukemia. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016]</dd>
|
||
<dt>Expression</dt>
|
||
<dd>Biased expression in lymph node (RPKM 12.2), spleen (RPKM 7.6) and 10 other tissues <a href="#gene-expression">See more</a></dd>
|
||
<dt>Orthologs</dt>
|
||
<dd class="ortholog-links">
|
||
<a href="/gene/11262/ortholog/">all</a>
|
||
</dd>
|
||
<dt style="padding-top:.5em;">
|
||
<span class="new-icon">NEW</span>
|
||
</dt>
|
||
<dd style="padding-top:.5em;">
|
||
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/11262/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="gene_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Gene table</a></strong>
|
||
<br />
|
||
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/11262/products/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="transcript_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Transcript table</a></strong>
|
||
</dd>
|
||
</dl>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-genomic-context">
|
||
<section class="rprt-section-header" id="genomic-context">
|
||
<h2 id="header-genomic-context">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-context .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Genomic context</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Genomic_Context" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div class="gc_cont">
|
||
<div class="gt_cont_contents">
|
||
<div style="float:right"><span>See SP140 in </span><a href="/genome/gdv/?context=gene&acc=11262" class="link-to-gdv genome-browser-link" data-genome-browser-link-sort="1" data-acc="GCF_000001405.40">Genome Data Viewer</a> </div>
|
||
<dl class="dl-chr-info" style="float:left;margin-top:0;">
|
||
<dt>Location: </dt>
|
||
<dd>
|
||
<span style="display:inline-block;">2q37.1</span>
|
||
</dd>
|
||
</dl>
|
||
</div>
|
||
<dl class="dl-chr-info exon-count">
|
||
<dt>Exon count: </dt>
|
||
<dd>35</dd>
|
||
</dl>
|
||
<div class="ui-ncbigrid-outer-div" id="genomic-context-tbl-location">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="">
|
||
<thead>
|
||
<tr>
|
||
<th style="max-width:15%">Annotation release</th>
|
||
<th style="max-width:10%">Status</th>
|
||
<th>Assembly</th>
|
||
<th>
|
||
<span title="Chromosome">Chr</span>
|
||
</th>
|
||
<th>Location</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td>RS_2024_08</td>
|
||
<td>current</td>
|
||
<td>GRCh38.p14 (<a href="/assembly/GCF_000001405.40/" ref="ncbi_uid=11262&link_uid=GCF_000001405.40">GCF_000001405.40</a>)</td>
|
||
<td>2</td>
|
||
<td>NC_000002.12 (230186151..230316571) </td>
|
||
</tr>
|
||
<tr>
|
||
<td>RS_2024_08</td>
|
||
<td>current</td>
|
||
<td>T2T-CHM13v2.0 (<a href="/assembly/GCF_009914755.1/" ref="ncbi_uid=11262&link_uid=GCF_009914755.1">GCF_009914755.1</a>)</td>
|
||
<td>2</td>
|
||
<td>NC_060926.1 (230669263..230808985) </td>
|
||
</tr>
|
||
<tr>
|
||
<td>RS_2024_09</td>
|
||
<td>previous assembly</td>
|
||
<td>GRCh37.p13 (<a href="/assembly/GCF_000001405.25/" ref="ncbi_uid=11262&link_uid=GCF_000001405.25">GCF_000001405.25</a>)</td>
|
||
<td>2</td>
|
||
<td>NC_000002.11 (231090451..231177930) </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<p class="withnote margin_t2em"><strong>Chromosome 2 - NC_000002.12</strong><img usemap="#nbrMap11262_568815596" border="0" alt="Genomic Context describing neighboring genes" src="/gutils/geneneighb.fcgi?geneid=11262&nuc_gi=568815596&n0=SLC16A14&n1=RNY4P19&n2=LOC107985995&n3=LOC127275933&n4=LOC129935744&n5=LOC129935745&n6=LOC127275934&n7=LOC129935746&n8=SP110&n9=LOC127275935&n10=SP140&n11=LOC129935747&n12=LOC129935748&n13=LOC129660912&n14=LOC129935749&n15=LOC129935750&n16=LOC129935751&n17=LOC129935752&n18=LOC129935753&n19=LOC127275936&n20=LOC129935754&n21=LOC129389006&n22=LOC126806547&n23=LOC129935755&n24=LOC129935756&n25=LOC129935757&n26=SP140L&n27=LOC127275937&n28=LOC129935758&n29=LOC105373925&n30=LOC129935759&n31=LOC129935760&n32=LOC129935761&n33=LOC129935762&n34=SP100&n35=LOC129935763&n36=LOC101928816&n37=LOC129935764&n38=LOC129935765&n39=RN7SL834P" /><map name="nbrMap11262_568815596" id="nbrMap11262_568815596">
|
||
<area shape="rect" onMouseOver="showtip(this,event,'solute carrier family 16 member 14')" onMouseOut="hidetip()" coords="22,23,88,31" alt="Neighboring gene solute carrier family 16 member 14" href="/gene/151473" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC107985995')" onMouseOut="hidetip()" coords="24,35,139,43" alt="Neighboring gene uncharacterized LOC107985995" href="/gene/107985995" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr2:230932348-230933118')" onMouseOut="hidetip()" coords="25,47,95,55" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:230932348-230933118" href="/gene/127275933" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17207')" onMouseOut="hidetip()" coords="26,59,96,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17207" href="/gene/129935744" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17208')" onMouseOut="hidetip()" coords="26,71,96,79" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17208" href="/gene/129935745" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'RNY4 pseudogene 19')" onMouseOut="hidetip()" coords="43,83,88,91" alt="Neighboring gene RNY4 pseudogene 19" href="/gene/100169834" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac hESC enhancer GRCh37_chr2:231005392-231005920')" onMouseOut="hidetip()" coords="76,95,146,103" alt="Neighboring gene H3K27ac hESC enhancer GRCh37_chr2:231005392-231005920" href="/gene/127275934" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 12407')" onMouseOut="hidetip()" coords="90,23,160,31" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12407" href="/gene/129935746" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'OCT4-NANOG hESC enhancer GRCh37_chr2:231044589-231045131')" onMouseOut="hidetip()" coords="104,47,174,55" alt="Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr2:231044589-231045131" href="/gene/127275935" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17209')" onMouseOut="hidetip()" coords="120,59,190,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17209" href="/gene/129935747" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'SP110 nuclear body protein')" onMouseOut="hidetip()" coords="129,71,198,79" alt="Neighboring gene SP110 nuclear body protein" href="/gene/3431" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17210')" onMouseOut="hidetip()" coords="130,83,200,91" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17210" href="/gene/129935748" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ReSE screen-validated silencer GRCh37_chr2:231084625-231084811')" onMouseOut="hidetip()" coords="132,107,202,115" alt="Neighboring gene ReSE screen-validated silencer GRCh37_chr2:231084625-231084811" href="/gene/129660912" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17212')" onMouseOut="hidetip()" coords="136,119,206,127" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17212" href="/gene/129935749" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17213')" onMouseOut="hidetip()" coords="136,131,206,139" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17213" href="/gene/129935750" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17214')" onMouseOut="hidetip()" coords="136,143,206,151" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17214" href="/gene/129935751" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17215')" onMouseOut="hidetip()" coords="136,155,206,163" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17215" href="/gene/129935752" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17216')" onMouseOut="hidetip()" coords="159,95,229,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17216" href="/gene/129935753" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:231129497-231130018')" onMouseOut="hidetip()" coords="164,23,234,31" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:231129497-231130018" href="/gene/127275936" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 12408')" onMouseOut="hidetip()" coords="180,47,250,55" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12408" href="/gene/129935754" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'MPRA-validated peak4075 silencer')" onMouseOut="hidetip()" coords="181,167,251,175" alt="Neighboring gene MPRA-validated peak4075 silencer" href="/gene/129389006" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'CDK7 strongly-dependent group 2 enhancer GRCh37_chr2:231176974-231178173')" onMouseOut="hidetip()" coords="197,59,267,67" alt="Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr2:231176974-231178173" href="/gene/126806547" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 12409')" onMouseOut="hidetip()" coords="201,71,271,79" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12409" href="/gene/129935755" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17217')" onMouseOut="hidetip()" coords="202,83,272,91" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17217" href="/gene/129935756" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17218')" onMouseOut="hidetip()" coords="207,107,277,115" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17218" href="/gene/129935757" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:231206345-231206936')" onMouseOut="hidetip()" coords="218,119,288,127" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:231206345-231206936" href="/gene/127275937" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17219')" onMouseOut="hidetip()" coords="222,131,292,139" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17219" href="/gene/129935758" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'SP140 nuclear body protein like')" onMouseOut="hidetip()" coords="237,23,323,31" alt="Neighboring gene SP140 nuclear body protein like" href="/gene/93349" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC105373925')" onMouseOut="hidetip()" coords="255,47,325,55" alt="Neighboring gene uncharacterized LOC105373925" href="/gene/105373925" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17220')" onMouseOut="hidetip()" coords="267,35,337,43" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17220" href="/gene/129935759" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17221')" onMouseOut="hidetip()" coords="267,95,337,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17221" href="/gene/129935761" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 12410')" onMouseOut="hidetip()" coords="267,143,337,151" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12410" href="/gene/129935760" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17222')" onMouseOut="hidetip()" coords="270,59,340,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17222" href="/gene/129935762" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17223')" onMouseOut="hidetip()" coords="287,71,357,79" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17223" href="/gene/129935763" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC101928816')" onMouseOut="hidetip()" coords="288,83,400,91" alt="Neighboring gene uncharacterized LOC101928816" href="/gene/101928816" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17224')" onMouseOut="hidetip()" coords="292,107,362,115" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17224" href="/gene/129935764" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'SP100 nuclear antigen')" onMouseOut="hidetip()" coords="305,119,423,127" alt="Neighboring gene SP100 nuclear antigen" href="/gene/6672" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 17225')" onMouseOut="hidetip()" coords="333,23,403,31" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17225" href="/gene/129935765" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'RNA, 7SL, cytoplasmic 834, pseudogene')" onMouseOut="hidetip()" coords="349,35,404,43" alt="Neighboring gene RNA, 7SL, cytoplasmic 834, pseudogene" href="/gene/106481148" />
|
||
</map>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-genomic-regions-transcripts-products">
|
||
<section class="rprt-section-header" id="genomic-regions-transcripts-products">
|
||
<h2 id="header-genomic-regions-transcripts-products">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-regions-transcripts-products .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Genomic regions, transcripts, and products</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Genomic_Regions_Transcripts_a" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<div style="text-align:right;">Go to <a href="#reference-sequences">reference sequence details</a></div>
|
||
</div>
|
||
<div>
|
||
<p class="choose">
|
||
<label for="accession" class="label">Genomic Sequence: </label>
|
||
<select name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.accessionList" sid="1" id="accessionList" data-taxid="9606" data-geneid="11262">
|
||
<option value="NC_000002.12_230186150_230316570">NC_000002.12 Chromosome 2 Reference GRCh38.p14 Primary Assembly</option>
|
||
<option value="NG_051286.2_44586_132065">NG_051286.2 RefSeqGene</option>
|
||
<option value="NC_060926.1_230669262_230808984">NC_060926.1 Chromosome 2 Alternate T2T-CHM13v2.0</option>
|
||
<option value="NC_000002.11_231090450_231177929">NC_000002.11 Chromosome 2 Reference GRCh37.p13 Primary Assembly</option>
|
||
</select>
|
||
</p>
|
||
</div>
|
||
<div id="NC_000002" class="divAccession">
|
||
<div class="seq-viewer">
|
||
<p class="note-link">
|
||
<strong>Go to nucleotide:</strong>
|
||
<a title="Nucleotide Graphic report" href="/nuccore/NC_000002.12?report=graph&from=230166587&to=230336133&app_context=Gene&assm_context=GCF_000001405.40" ref="ordinalpos=1&ncbi_uid=11262&link_uid=NC_000002.12">Graphics</a>
|
||
<a title="Nucleotide FASTA report" href="/nuccore/NC_000002.12?report=fasta&from=230186151&to=230316571" ref="ordinalpos=1&ncbi_uid=11262&link_uid=NC_000002.12">FASTA</a>
|
||
<a title="Nucleotide GenBank report" href="/nuccore/NC_000002.12?report=genbank&from=230186151&to=230316571" ref="ordinalpos=1&ncbi_uid=11262&link_uid=NC_000002.12">GenBank</a>
|
||
</p>
|
||
<div id="divNC_000002" class="SeqViewerApp" style="clear:both;" data-sv="appname=ncbigene&embedded=true&noslider=1&id=NC_000002.12&from=230166587&to=230336133&app_context=Gene&assm_context=GCF_000001405.40">
|
||
<a href="?appname=ncbigene&embedded=true&noslider=1&id=NC_000002.12&from=230166587&to=230336133&app_context=Gene&assm_context=GCF_000001405.40"></a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000002.12" sid="1" type="hidden" id="nucleotideLink_NC_000002_12_230186150_230316570" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_000002.12?report=graph&amp;from=230166587&amp;to=230336133&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" ref="ordinalpos=1&amp;ncbi_uid=11262&amp;link_uid=NC_000002.12">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_000002.12?report=fasta&amp;from=230186151&amp;to=230316571" ref="ordinalpos=1&amp;ncbi_uid=11262&amp;link_uid=NC_000002.12">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_000002.12?report=genbank&amp;from=230186151&amp;to=230316571" ref="ordinalpos=1&amp;ncbi_uid=11262&amp;link_uid=NC_000002.12">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000002.12" sid="1" type="hidden" id="relString_NC_000002_12_230186150_230316570" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000002.12&amp;from=230166587&amp;to=230336133&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NG_051286.2" sid="1" type="hidden" id="nucleotideLink_NG_051286_2_44586_132065" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NG_051286.2?report=graph&amp;from=31464&amp;to=145187&amp;tracks=[key:sequence_track,name:Sequence,display_name:Sequence,category:Sequence,annots:Sequence,ShowLabel:false][key:gene_model_track,name:Genes---Unnamed,display_name:Genes,annots:Unnamed,Options:ShowAllButGenes,SNPs:false,CDSProductFeats:false,ShowLabelsForAllFeatures:true,HighlightMode:2][key:SNP_track,name:SNP,annots:SNP,Layout:Adaptive][key:SNP_Bins_track,name:Clinical Variants][key:SNP_Bins_track,name:Cited Variants][key:GWAS_track,name:GWAS Tracks,display_name:Association Results][key:alignment_track,category:Alignments,annots:Unnamed][key:alignment_track,category:Alignments,annots:NA000079160.1][key:alignment_track,category:Alignments,annots:NA000010065.1]" ref="ordinalpos=1&amp;ncbi_uid=11262&amp;link_uid=NG_051286.2">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NG_051286.2?report=fasta&amp;from=44587&amp;to=132066" ref="ordinalpos=1&amp;ncbi_uid=11262&amp;link_uid=NG_051286.2">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NG_051286.2?report=genbank&amp;from=44587&amp;to=132066" ref="ordinalpos=1&amp;ncbi_uid=11262&amp;link_uid=NG_051286.2">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NG_051286.2" sid="1" type="hidden" id="relString_NG_051286_2_44586_132065" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NG_051286.2&amp;from=31464&amp;to=145187&amp;tracks=[key:sequence_track,name:Sequence,display_name:Sequence,category:Sequence,annots:Sequence,ShowLabel:false][key:gene_model_track,name:Genes---Unnamed,display_name:Genes,annots:Unnamed,Options:ShowAllButGenes,SNPs:false,CDSProductFeats:false,ShowLabelsForAllFeatures:true,HighlightMode:2][key:SNP_track,name:SNP,annots:SNP,Layout:Adaptive][key:SNP_Bins_track,name:Clinical Variants][key:SNP_Bins_track,name:Cited Variants][key:GWAS_track,name:GWAS Tracks,display_name:Association Results][key:alignment_track,category:Alignments,annots:Unnamed][key:alignment_track,category:Alignments,annots:NA000079160.1][key:alignment_track,category:Alignments,annots:NA000010065.1]" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_060926.1" sid="1" type="hidden" id="nucleotideLink_NC_060926_1_230669262_230808984" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_060926.1?report=graph&amp;from=230648304&amp;to=230829942&amp;app_context=Gene&amp;assm_context=GCF_009914755.1" ref="ordinalpos=1&amp;ncbi_uid=11262&amp;link_uid=NC_060926.1">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_060926.1?report=fasta&amp;from=230669263&amp;to=230808985" ref="ordinalpos=1&amp;ncbi_uid=11262&amp;link_uid=NC_060926.1">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_060926.1?report=genbank&amp;from=230669263&amp;to=230808985" ref="ordinalpos=1&amp;ncbi_uid=11262&amp;link_uid=NC_060926.1">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_060926.1" sid="1" type="hidden" id="relString_NC_060926_1_230669262_230808984" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_060926.1&amp;from=230648304&amp;to=230829942&amp;app_context=Gene&amp;assm_context=GCF_009914755.1" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000002.11" sid="1" type="hidden" id="nucleotideLink_NC_000002_11_231090450_231177929" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_000002.11?report=graph&amp;from=231077328&amp;to=231191051&amp;app_context=Gene&amp;assm_context=GCF_000001405.25" ref="ordinalpos=1&amp;ncbi_uid=11262&amp;link_uid=NC_000002.11">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_000002.11?report=fasta&amp;from=231090451&amp;to=231177930" ref="ordinalpos=1&amp;ncbi_uid=11262&amp;link_uid=NC_000002.11">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_000002.11?report=genbank&amp;from=231090451&amp;to=231177930" ref="ordinalpos=1&amp;ncbi_uid=11262&amp;link_uid=NC_000002.11">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000002.11" sid="1" type="hidden" id="relString_NC_000002_11_231090450_231177929" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000002.11&amp;from=231077328&amp;to=231191051&amp;app_context=Gene&amp;assm_context=GCF_000001405.25" />
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-gene-expression">
|
||
<section class="rprt-section-header" id="gene-expression">
|
||
<h2 id="header-gene-expression">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-gene-expression .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Expression</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Expression" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<div style="text-align:right;">
|
||
<a href="/gene/11262/?report=expression" data-url="/gene/11262/?report=expression" id="gene-expression-see-details">See details</a>
|
||
</div>
|
||
<div id="gene-expression-app" data-url="https://www.ncbi.nlm.nih.gov/gene/11262" data-report-type="summary">
|
||
<div>
|
||
<script type="text/javascript">
|
||
|
||
window.tissues_data = {'adrenal 10wk': {'id': '11262_Adrenal_10wk_PRJNA270632', 'gene': 11262, 'source_name': 'adrenal 10wk', 'full_rpkm': 0.188711, 'exp_rpkm': 0.189, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986060}, 'adrenal 16wk': {'id': '11262_Adrenal_16wk_PRJNA270632', 'gene': 11262, 'source_name': 'adrenal 16wk', 'full_rpkm': 0.105505, 'exp_rpkm': 0.106, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986061}, 'adrenal 18wk': {'id': '11262_Adrenal_18wk_PRJNA270632', 'gene': 11262, 'source_name': 'adrenal 18wk', 'full_rpkm': 0.133935, 'exp_rpkm': 0.134, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986062}, 'adrenal 20wk': {'id': '11262_Adrenal_20wk_PRJNA270632', 'gene': 11262, 'source_name': 'adrenal 20wk', 'full_rpkm': 0.112468, 'exp_rpkm': 0.112, 'var': 1.096626e-06, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986063}, 'heart 10wk': {'id': '11262_Heart_10wk;_PRJNA270632', 'gene': 11262, 'source_name': 'heart 10wk', 'full_rpkm': 0.0626078, 'exp_rpkm': 0.0626, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986064}, 'heart 11wk': {'id': '11262_Heart_11wk;_PRJNA270632', 'gene': 11262, 'source_name': 'heart 11wk', 'full_rpkm': 0.0334978, 'exp_rpkm': 0.0335, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986065}, 'heart 17wk': {'id': '11262_Heart_17wk;_PRJNA270632', 'gene': 11262, 'source_name': 'heart 17wk', 'full_rpkm': 0.0123245, 'exp_rpkm': 0.0123, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986066}, 'heart 18wk': {'id': '11262_Heart_18wk;_PRJNA270632', 'gene': 11262, 'source_name': 'heart 18wk', 'full_rpkm': 0.0263909, 'exp_rpkm': 0.0264, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986067}, 'heart 20wk': {'id': '11262_Heart_20wk_PRJNA270632', 'gene': 11262, 'source_name': 'heart 20wk', 'full_rpkm': 0.00972821, 'exp_rpkm': 0.00973, 'var': 1.4379e-05, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986068}, 'intestine 10wk': {'id': '11262_Intestine_10wk_PRJNA270632', 'gene': 11262, 'source_name': 'intestine 10wk', 'full_rpkm': 0.0691465, 'exp_rpkm': 0.0691, 'var': 0.000665958, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986069}, 'intestine 11wk': {'id': '11262_Intestine_11wk_PRJNA270632', 'gene': 11262, 'source_name': 'intestine 11wk', 'full_rpkm': 0.0804373, 'exp_rpkm': 0.0804, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986070}, 'intestine 15wk': {'id': '11262_Intestine_15wk_PRJNA270632', 'gene': 11262, 'source_name': 'intestine 15wk', 'full_rpkm': 0.121356, 'exp_rpkm': 0.121, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986071}, 'intestine 17wk': {'id': '11262_Intestine_17wk_PRJNA270632', 'gene': 11262, 'source_name': 'intestine 17wk', 'full_rpkm': 0.0788247, 'exp_rpkm': 0.0788, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986072}, 'intestine 20wk': {'id': '11262_Intestine_20wk_PRJNA270632', 'gene': 11262, 'source_name': 'intestine 20wk', 'full_rpkm': 0.152815, 'exp_rpkm': 0.153, 'var': 0.00298132, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986073}, 'kidney 10wk': {'id': '11262_Kidney_10wk_PRJNA270632', 'gene': 11262, 'source_name': 'kidney 10wk', 'full_rpkm': 0.0641552, 'exp_rpkm': 0.0642, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986074}, 'kidney 16wk': {'id': '11262_Kidney_16wk_PRJNA270632', 'gene': 11262, 'source_name': 'kidney 16wk', 'full_rpkm': 0.030139, 'exp_rpkm': 0.0301, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986075}, 'kidney 20wk': {'id': '11262_Kidney_20wk_PRJNA270632', 'gene': 11262, 'source_name': 'kidney 20wk', 'full_rpkm': 0.0142802, 'exp_rpkm': 0.0143, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986076}, 'lung 10wk': {'id': '11262_Lung_10wk_PRJNA270632', 'gene': 11262, 'source_name': 'lung 10wk', 'full_rpkm': 0.0512909, 'exp_rpkm': 0.0513, 'var': 0.000231252, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986077}, 'lung 17wk': {'id': '11262_Lung_17wk_PRJNA270632', 'gene': 11262, 'source_name': 'lung 17wk', 'full_rpkm': 0.0637469, 'exp_rpkm': 0.0637, 'var': 9.1635e-07, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986078}, 'lung 20wk': {'id': '11262_Lung_20wk_PRJNA270632', 'gene': 11262, 'source_name': 'lung 20wk', 'full_rpkm': 0.111494, 'exp_rpkm': 0.111, 'var': 0.00121248, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986079}, 'stomach 10wk': {'id': '11262_Stomach_10wk_PRJNA270632', 'gene': 11262, 'source_name': 'stomach 10wk', 'full_rpkm': 0.0686784, 'exp_rpkm': 0.0687, 'var': 0.0001793346, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986080}, 'stomach 16wk': {'id': '11262_Stomach_16wk_PRJNA270632', 'gene': 11262, 'source_name': 'stomach 16wk', 'full_rpkm': 0.103755, 'exp_rpkm': 0.104, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986081}, 'stomach 18wk': {'id': '11262_Stomach_18wk_PRJNA270632', 'gene': 11262, 'source_name': 'stomach 18wk', 'full_rpkm': 0.0515004, 'exp_rpkm': 0.0515, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986082}, 'stomach 20wk': {'id': '11262_Stomach_20wk_PRJNA270632', 'gene': 11262, 'source_name': 'stomach 20wk', 'full_rpkm': 0.118929, 'exp_rpkm': 0.119, 'var': 0.001305687, 'project_desc': 'PRJNA270632', '_version_': 1785734417033986083}};
|
||
|
||
|
||
|
||
|
||
window.details_data = {"adrenal 10wk": [{"id": "metadata_9606_SAMN03267754", "gene": 11262, "sample_id": "SAMN03267754", "full_rpkm": 0.188711, "exp_rpkm": 0.189, "exp_total": 6700, "project_desc": "PRJNA270632", "_version_": 1785734387345653765, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 10wk", "exp_Mcount": 4852.92}], "adrenal 16wk": [{"id": "metadata_9606_SAMN03267755", "gene": 11262, "sample_id": "SAMN03267755", "full_rpkm": 0.105505, "exp_rpkm": 0.106, "exp_total": 5611, "project_desc": "PRJNA270632", "_version_": 1785734387345653764, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 16wk", "exp_Mcount": 7269.31}], "adrenal 18wk": [{"id": "metadata_9606_SAMN03267761", "gene": 11262, "sample_id": "SAMN03267761", "full_rpkm": 0.133935, "exp_rpkm": 0.134, "exp_total": 6541, "project_desc": "PRJNA270632", "_version_": 1785734387345653763, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 18wk", "exp_Mcount": 6675.41}], "adrenal 20wk": [{"id": "metadata_9606_SAMN03267762", "gene": 11262, "sample_id": "SAMN03267762", "full_rpkm": 0.111421, "exp_rpkm": 0.111, "exp_total": 6164, "project_desc": "PRJNA270632", "_version_": 1785734387345653761, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 20wk", "exp_Mcount": 7561.75}, {"id": "metadata_9606_SAMN03267753", "gene": 11262, "sample_id": "SAMN03267753", "full_rpkm": 0.113515, "exp_rpkm": 0.114, "exp_total": 5521, "project_desc": "PRJNA270632", "_version_": 1785734387345653762, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 20wk", "exp_Mcount": 6647.98}], "heart 10wk": [{"id": "metadata_9606_SAMN03267750", "gene": 11262, "sample_id": "SAMN03267750", "full_rpkm": 0.0626078, "exp_rpkm": 0.0626, "exp_total": 2446, "project_desc": "PRJNA270632", "_version_": 1785734387345653760, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 10wk", "exp_Mcount": 5340.16}], "heart 11wk": [{"id": "metadata_9606_SAMN03267763", "gene": 11262, "sample_id": "SAMN03267763", "full_rpkm": 0.0334978, "exp_rpkm": 0.0335, "exp_total": 1455, "project_desc": "PRJNA270632", "_version_": 1785734387344605210, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 11wk", "exp_Mcount": 5937.09}], "heart 17wk": [{"id": "metadata_9606_SAMN03267757", "gene": 11262, "sample_id": "SAMN03267757", "full_rpkm": 0.0123245, "exp_rpkm": 0.0123, "exp_total": 713, "project_desc": "PRJNA270632", "_version_": 1785734387344605209, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 17wk", "exp_Mcount": 7907.66}], "heart 18wk": [{"id": "metadata_9606_SAMN03267751", "gene": 11262, "sample_id": "SAMN03267751", "full_rpkm": 0.0263909, "exp_rpkm": 0.0264, "exp_total": 1232, "project_desc": "PRJNA270632", "_version_": 1785734387344605208, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 18wk", "exp_Mcount": 6380.91}], "heart 20wk": [{"id": "metadata_9606_SAMN03267756", "gene": 11262, "sample_id": "SAMN03267756", "full_rpkm": 0.00950575, "exp_rpkm": 0.00951, "exp_total": 755, "project_desc": "PRJNA270632", "_version_": 1785734387344605205, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 20wk", "exp_Mcount": 10856.4}, {"id": "metadata_9606_SAMN03267764", "gene": 11262, "sample_id": "SAMN03267764", "full_rpkm": 0.0144796, "exp_rpkm": 0.0145, "exp_total": 540, "project_desc": "PRJNA270632", "_version_": 1785734387344605206, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 20wk", "exp_Mcount": 5097.56}, {"id": "metadata_9606_SAMN03267760", "gene": 11262, "sample_id": "SAMN03267760", "full_rpkm": 0.00519924, "exp_rpkm": 0.0052, "exp_total": 228, "project_desc": "PRJNA270632", "_version_": 1785734387344605207, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "heart 20wk", "exp_Mcount": 5994.06}], "intestine 10wk": [{"id": "metadata_9606_SAMN03267752", "gene": 11262, "sample_id": "SAMN03267752", "full_rpkm": 0.0433404, "exp_rpkm": 0.0433, "exp_total": 2476, "project_desc": "PRJNA270632", "_version_": 1785734387344605203, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 10wk", "exp_Mcount": 7808.8}, {"id": "metadata_9606_SAMN03267759", "gene": 11262, "sample_id": "SAMN03267759", "full_rpkm": 0.0949527, "exp_rpkm": 0.095, "exp_total": 4798, "project_desc": "PRJNA270632", "_version_": 1785734387344605204, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 10wk", "exp_Mcount": 6906.84}], "intestine 11wk": [{"id": "metadata_9606_SAMN03267758", "gene": 11262, "sample_id": "SAMN03267758", "full_rpkm": 0.0804373, "exp_rpkm": 0.0804, "exp_total": 2551, "project_desc": "PRJNA270632", "_version_": 1785734387344605202, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 11wk", "exp_Mcount": 4334.9}], "intestine 15wk": [{"id": "metadata_9606_SAMN03267775", "gene": 11262, "sample_id": "SAMN03267775", "full_rpkm": 0.121356, "exp_rpkm": 0.121, "exp_total": 3534, "project_desc": "PRJNA270632", "_version_": 1785734387344605201, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 15wk", "exp_Mcount": 3980.45}], "intestine 17wk": [{"id": "metadata_9606_SAMN03267782", "gene": 11262, "sample_id": "SAMN03267782", "full_rpkm": 0.0788247, "exp_rpkm": 0.0788, "exp_total": 5574, "project_desc": "PRJNA270632", "_version_": 1785734387344605200, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 17wk", "exp_Mcount": 9665.65}], "intestine 20wk": [{"id": "metadata_9606_SAMN03267766", "gene": 11262, "sample_id": "SAMN03267766", "full_rpkm": 0.0982139, "exp_rpkm": 0.0982, "exp_total": 2990, "project_desc": "PRJNA270632", "_version_": 1785734387344605198, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 20wk", "exp_Mcount": 4161.26}, {"id": "metadata_9606_SAMN03267769", "gene": 11262, "sample_id": "SAMN03267769", "full_rpkm": 0.207417, "exp_rpkm": 0.207, "exp_total": 5909, "project_desc": "PRJNA270632", "_version_": 1785734387344605199, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 20wk", "exp_Mcount": 3894.01}], "kidney 10wk": [{"id": "metadata_9606_SAMN03267784", "gene": 11262, "sample_id": "SAMN03267784", "full_rpkm": 0.0641552, "exp_rpkm": 0.0642, "exp_total": 2218, "project_desc": "PRJNA270632", "_version_": 1785734387344605197, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "kidney 10wk", "exp_Mcount": 4725.59}], "kidney 16wk": [{"id": "metadata_9606_SAMN03267772", "gene": 11262, "sample_id": "SAMN03267772", "full_rpkm": 0.030139, "exp_rpkm": 0.0301, "exp_total": 3371, "project_desc": "PRJNA270632", "_version_": 1785734387344605196, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "kidney 16wk", "exp_Mcount": 15288.2}], "kidney 20wk": [{"id": "metadata_9606_SAMN03267777", "gene": 11262, "sample_id": "SAMN03267777", "full_rpkm": 0.0142802, "exp_rpkm": 0.0143, "exp_total": 1074, "project_desc": "PRJNA270632", "_version_": 1785734387344605195, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "kidney 20wk", "exp_Mcount": 10280.0}], "lung 10wk": [{"id": "metadata_9606_SAMN03267770", "gene": 11262, "sample_id": "SAMN03267770", "full_rpkm": 0.0664978, "exp_rpkm": 0.0665, "exp_total": 2896, "project_desc": "PRJNA270632", "_version_": 1785734387344605193, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 10wk", "exp_Mcount": 5952.75}, {"id": "metadata_9606_SAMN03267767", "gene": 11262, "sample_id": "SAMN03267767", "full_rpkm": 0.0360839, "exp_rpkm": 0.0361, "exp_total": 1381, "project_desc": "PRJNA270632", "_version_": 1785734387344605194, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 10wk", "exp_Mcount": 5231.26}], "lung 17wk": [{"id": "metadata_9606_SAMN03267778", "gene": 11262, "sample_id": "SAMN03267778", "full_rpkm": 0.0627896, "exp_rpkm": 0.0628, "exp_total": 2873, "project_desc": "PRJNA270632", "_version_": 1785734387344605191, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 17wk", "exp_Mcount": 6254.23}, {"id": "metadata_9606_SAMN03267776", "gene": 11262, "sample_id": "SAMN03267776", "full_rpkm": 0.0647041, "exp_rpkm": 0.0647, "exp_total": 1772, "project_desc": "PRJNA270632", "_version_": 1785734387344605192, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 17wk", "exp_Mcount": 3743.33}], "lung 20wk": [{"id": "metadata_9606_SAMN03267780", "gene": 11262, "sample_id": "SAMN03267780", "full_rpkm": 0.0766733, "exp_rpkm": 0.0767, "exp_total": 5200, "project_desc": "PRJNA270632", "_version_": 1785734387344605189, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 20wk", "exp_Mcount": 9270.13}, {"id": "metadata_9606_SAMN03267768", "gene": 11262, "sample_id": "SAMN03267768", "full_rpkm": 0.146315, "exp_rpkm": 0.146, "exp_total": 6800, "project_desc": "PRJNA270632", "_version_": 1785734387344605190, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 20wk", "exp_Mcount": 6352.54}], "stomach 10wk": [{"id": "metadata_9606_SAMN03267773", "gene": 11262, "sample_id": "SAMN03267773", "full_rpkm": 0.0820699, "exp_rpkm": 0.0821, "exp_total": 3952, "project_desc": "PRJNA270632", "_version_": 1785734387344605187, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 10wk", "exp_Mcount": 6582.02}, {"id": "metadata_9606_SAMN03267779", "gene": 11262, "sample_id": "SAMN03267779", "full_rpkm": 0.0552868, "exp_rpkm": 0.0553, "exp_total": 2926, "project_desc": "PRJNA270632", "_version_": 1785734387344605188, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 10wk", "exp_Mcount": 7234.02}], "stomach 16wk": [{"id": "metadata_9606_SAMN03267774", "gene": 11262, "sample_id": "SAMN03267774", "full_rpkm": 0.103755, "exp_rpkm": 0.104, "exp_total": 4721, "project_desc": "PRJNA270632", "_version_": 1785734387344605186, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 16wk", "exp_Mcount": 6219.43}], "stomach 18wk": [{"id": "metadata_9606_SAMN03267771", "gene": 11262, "sample_id": "SAMN03267771", "full_rpkm": 0.0515004, "exp_rpkm": 0.0515, "exp_total": 2193, "project_desc": "PRJNA270632", "_version_": 1785734387344605185, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 18wk", "exp_Mcount": 5820.42}], "stomach 20wk": [{"id": "metadata_9606_SAMN03267765", "gene": 11262, "sample_id": "SAMN03267765", "full_rpkm": 0.169331, "exp_rpkm": 0.169, "exp_total": 5568, "project_desc": "PRJNA270632", "_version_": 1785734387342508032, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4494.58}, {"id": "metadata_9606_SAMN03267781", "gene": 11262, "sample_id": "SAMN03267781", "full_rpkm": 0.101028, "exp_rpkm": 0.101, "exp_total": 3375, "project_desc": "PRJNA270632", "_version_": 1785734387343556608, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4566.24}, {"id": "metadata_9606_SAMN03267783", "gene": 11262, "sample_id": "SAMN03267783", "full_rpkm": 0.0864289, "exp_rpkm": 0.0864, "exp_total": 3038, "project_desc": "PRJNA270632", "_version_": 1785734387344605184, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4804.58}]}
|
||
window.taxId = 9606
|
||
</script>
|
||
|
||
|
||
<div>
|
||
|
||
|
||
|
||
<select name="p" id="project-selector">
|
||
|
||
|
||
<option value="SRP051249" selected="selected" data-bioproject="PRJNA270632">
|
||
|
||
Tissue-specific circular RNA induction during human fetal development
|
||
|
||
</option>
|
||
|
||
|
||
|
||
<option value="SRP056969" data-bioproject="PRJNA280600">
|
||
|
||
RNA sequencing of total RNA from 20 human tissues
|
||
|
||
|
||
</option>
|
||
|
||
|
||
|
||
<option value="ERP003613" data-bioproject="PRJEB4337">
|
||
|
||
HPA RNA-seq normal tissues
|
||
|
||
|
||
</option>
|
||
|
||
|
||
|
||
</select>
|
||
|
||
|
||
|
||
<ul id="project-summary">
|
||
<li id="project-summary-title">Project title:
|
||
|
||
Tissue-specific circular RNA induction during human fetal development
|
||
|
||
</li>
|
||
|
||
|
||
<li id="project-summary-desc">Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA</li>
|
||
|
||
|
||
|
||
<li id="project-summary-bioprojects">BioProject: <a href="/bioproject/PRJNA270632/">PRJNA270632</a>
|
||
</li>
|
||
|
||
<li id="project-summary-pubs">Publication:
|
||
|
||
|
||
<span><a href="/pubmed/26076956/">PMID 26076956</a></span>
|
||
|
||
</li>
|
||
|
||
|
||
<li id="project-summary-analysis-date">Analysis date: Mon Apr 2 22:54:59 2018</li>
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
<div id="gene-expr-details" class="expression-chart"></div>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<script type="text/javascript" src="https://www.gstatic.com/charts/loader.js"></script>
|
||
<script type="text/javascript">
|
||
google.charts.load('current', {
|
||
'packages':[ 'corechart']
|
||
});
|
||
|
||
</script>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-bibliography">
|
||
<section class="rprt-section-header" id="bibliography"><h2 id="header-bibliography"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-bibliography .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Bibliography</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Bibliography" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
|
||
<div class="rprt-section-body" style="">
|
||
<div class="generif-pubmed">
|
||
<h3 id="relatedarticlesinpubmed">
|
||
<a href="#" class="jig-ncbitoggler-open">Related articles in PubMed</a>
|
||
</h3>
|
||
<div class="generefbl-link">
|
||
<ol class="generef-link">
|
||
<li>
|
||
<a href="/pubmed/36600652/" ref="ordinalpos=1&ncbi_uid=11262&link_uid=36600652">SP140 inhibits STAT1 signaling, induces IFN-γ in tumor-associated macrophages, and is a predictive biomarker of immunotherapy response.</a>
|
||
<span class="pubmed-auth-date"> Tanagala KKK, <em>et al</em>. J Immunother Cancer, 2022 Dec. PMID 36600652, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC9748993/" ref="ordinalpos=0&ncbi_uid=11262&link_uid=PMC9748993">Free PMC Article</a></span></span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/8910577/" ref="ordinalpos=2&ncbi_uid=11262&link_uid=8910577">Identification and characterization of a leukocyte-specific component of the nuclear body.</a>
|
||
<span class="pubmed-auth-date"> Bloch DB, <em>et al</em>. J Biol Chem, 1996 Nov 15. PMID 8910577</span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/19861957/" ref="ordinalpos=3&ncbi_uid=11262&link_uid=19861957">PML nuclear body component Sp140 is a novel autoantigen in primary biliary cirrhosis.</a>
|
||
<span class="pubmed-auth-date"> Granito A, <em>et al</em>. Am J Gastroenterol, 2010 Jan. PMID 19861957</span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/30465816/" ref="ordinalpos=4&ncbi_uid=11262&link_uid=30465816">Sp140 is a multi-SUMO-1 target and its PHD finger promotes SUMOylation of the adjacent Bromodomain.</a>
|
||
<span class="pubmed-auth-date"> Zucchelli C, <em>et al</em>. Biochim Biophys Acta Gen Subj, 2019 Feb. PMID 30465816</span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/30102396/" ref="ordinalpos=5&ncbi_uid=11262&link_uid=30102396">SP140 regulates the expression of immune-related genes associated with multiple sclerosis and other autoimmune diseases by NF-κB inhibition.</a>
|
||
<span class="pubmed-auth-date"> Karaky M, <em>et al</em>. Hum Mol Genet, 2018 Dec 1. PMID 30102396</span>
|
||
</li>
|
||
</ol>
|
||
<p class="see-all-pm">
|
||
<a href="/pubmed?LinkName=gene_pubmed&from_uid=11262" title="See all 32 citations in Pubmed">See all (32) citations in PubMed</a>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="generif-pubmed generif">
|
||
<h3 id="generifsgenereferencesintofunctions">
|
||
<a href="#" class="jig-ncbitoggler-open">GeneRIFs: Gene References Into Functions</a>
|
||
</h3>
|
||
<div>
|
||
<a href="/gene/about-generif" class="whatisthis">What's a GeneRIF?</a>
|
||
<div class="generefbl-link">
|
||
<ol class="generef-link">
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/39162523" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=11262&link_uid=39162523">Transcriptional regulators SP110 and SP140 modulate inflammatory response genes in Mycobacterium tuberculosis-infected human macrophages.</a>
|
||
<div id="gene-popper1" class="gene-rif-popper">Title: Transcriptional regulators SP110 and SP140 modulate inflammatory response genes in Mycobacterium tuberculosis-infected human macrophages.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/36600652" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=11262&link_uid=36600652">SP140 inhibits STAT1 signaling, induces IFN-gamma in tumor-associated macrophages, and is a predictive biomarker of immunotherapy response.</a>
|
||
<div id="gene-popper2" class="gene-rif-popper">Title: SP140 inhibits STAT1 signaling, induces IFN-γ in tumor-associated macrophages, and is a predictive biomarker of immunotherapy response.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/36130593" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=11262&link_uid=36130593">Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease.</a>
|
||
<div id="gene-popper3" class="gene-rif-popper">Title: Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/35952671" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=11262&link_uid=35952671">Epigenetic reader SP140 loss of function drives Crohn's disease due to uncontrolled macrophage topoisomerases.</a>
|
||
<div id="gene-popper4" class="gene-rif-popper">Title: Epigenetic reader SP140 loss of function drives Crohn's disease due to uncontrolled macrophage topoisomerases.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/30465816" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=11262&link_uid=30465816">The Sp140 is multi-SUMOylated and its PHD finger works as versatile protein-protein interaction platform promoting intramolecular SUMOylation of the adjacent BRD.</a>
|
||
<div id="gene-popper5" class="gene-rif-popper">Title: Sp140 is a multi-SUMO-1 target and its PHD finger promotes SUMOylation of the adjacent Bromodomain.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/30102396" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=11262&link_uid=30102396">Our findings showed that SP140 is an important repressor of genes implicated in inflammation, suggesting that decreased expression of SP140, promoted by the rs28445040-T risk variant, may lead to up-regulation of these genes by means of NF-kappaB inhibition in B cells.</a>
|
||
<div id="gene-popper6" class="gene-rif-popper">Title: SP140 regulates the expression of immune-related genes associated with multiple sclerosis and other autoimmune diseases by NF-κB inhibition.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/26888452" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=11262&link_uid=26888452">IL1R2 hypomethylation and androgen receptor hypermethylation may constitute an important determinant of disease severity, whereas NPR2 hypomethylation and SP140 hypermethylation may provide a biomarker for vulnerability to excessive daytime sleepiness in Obstructive Sleep Apnea</a>
|
||
<div id="gene-popper7" class="gene-rif-popper">Title: Whole Genome DNA Methylation Analysis of Obstructive Sleep Apnea: IL1R2, NPR2, AR, SP140 Methylation and Clinical Phenotype.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/26152201" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=11262&link_uid=26152201">Data identified rs28445040 variant in SP140 gene as the causal factor for skipping of exon 7 and the most associated with multiple sclerosis.</a>
|
||
<div id="gene-popper8" class="gene-rif-popper">Title: A functional variant that affects exon-skipping and protein expression of SP140 as genetic mechanism predisposing to multiple sclerosis.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/20731705,20332261" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=11262&link_uid=20731705,20332261">Observational study of gene-disease association. (HuGE Navigator)</a>
|
||
<div id="gene-popper9" class="gene-rif-popper">Title: Genetic susceptibility for chronic lymphocytic leukemia among Chinese in Hong Kong.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/12368356" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=11262&link_uid=12368356">the nuclear body protein Sp140, was found specifically in all NP cells (n = 12 cell lines tested; P < or = 0.001), and HIV-1 infection induced its partial dispersal from nuclear bodies into cytosolic colocalization with Vif</a>
|
||
<div id="gene-popper10" class="gene-rif-popper">Title: Implication of the lymphocyte-specific nuclear body protein Sp140 in an innate response to human immunodeficiency virus type 1.</div>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
<div class="submit-genrif">
|
||
<span>Submit:</span>
|
||
<a href="/gene/submit-generif/?geneId=11262&sym=SP140&name=SP140 nuclear body protein&org=Homo sapiens">New GeneRIF</a>
|
||
<a href="/RefSeq/update.cgi?geneid=11262&symbol=SP140;task=fixpub">Correction</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-phenotypes">
|
||
<section class="rprt-section-header" id="phenotypes">
|
||
<h2 id="header-phenotypes">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-phenotypes .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Phenotypes</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Phenotype" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body info-phenotype">
|
||
<p class="nochild-link">
|
||
<a href="/gtr/tests/?term=SP140[gene]">Find tests for this gene in the NIH Genetic Testing Registry (GTR)</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/gap/PheGenI?tab=1&gene=11262">Review eQTL and phenotype association data in this region using PheGenI</a>
|
||
</p>
|
||
<div>
|
||
<h3 id="ebigwascatalog">EBI GWAS Catalog</h3>
|
||
<table class="jig-ncbigrid gtr-associated-cond" data-jigconfig="isPageable: true, pageSize: 10">
|
||
<thead>
|
||
<tr>
|
||
<th class="description">Description</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td>A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/24292274">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/24292274">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/18758461">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/18758461">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/22700719">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/22700719">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/21833088">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/21833088">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/23770605">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/23770605">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/21102463">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/21102463">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/23128233">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/23128233">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-variation">
|
||
<section class="rprt-section-header" id="variation">
|
||
<h2 id="header-variation">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-variation .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Variation</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.variation" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<p class="nochild-link">
|
||
<a href="/clinvar/?term=SP140[gene]" ref="log$=recordlinks">See variants in ClinVar</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/dbvar?LinkName=gene_dbvar&from_uid=11262" ref="log$=recordlinks">See studies and variants in dbVar</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/variation/view/?q=11262[geneid]&assm=GCF_000001405.25" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh37.p13)">See Variation Viewer (GRCh37.p13)</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/variation/view/?q=11262[geneid]" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh38)">See Variation Viewer (GRCh38)</a>
|
||
</p>
|
||
<set></set>
|
||
<set></set>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-HIV-1-interactions">
|
||
<section class="rprt-section-header" id="HIV-1-interactions">
|
||
<h2 id="header-HIV-1-interactions">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-HIV-1-interactions .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">HIV-1 interactions</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.HIV1_interactions" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div class="fgrid">
|
||
<h3 id="proteininteractions">Protein interactions</h3>
|
||
<table summary="protein interactions" class="jig-ncbigrid">
|
||
<thead>
|
||
<tr>
|
||
<th id="hivprotein">Protein</th>
|
||
<th id="gene-hivprotein">Gene</th>
|
||
<th id="hivinter">Interaction</th>
|
||
<th id="hivpub">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="hivprotein">
|
||
<a href="/protein/9629361">Vif</a>
|
||
</td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155459">vif</a>
|
||
</td>
|
||
<td headers="hivinter">Wild-type HIV-1 Vif binds to the carboxyl-terminal region of Sp140 between amino acids 527-836, while Vif mutants with deletions of amino acids 12-23, 43-59, 73-87 or 97-112 are strongly inhibited in their binding to Sp140</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 19149577,12368356" href="/pubmed/19149577,12368356">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein"></td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155459">vif</a>
|
||
</td>
|
||
<td headers="hivinter">HIV-1 Vif may enhance the cytosolic retention of Sp140</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 19149577,12368356" href="/pubmed/19149577,12368356">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="hivprotein"></td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155459">vif</a>
|
||
</td>
|
||
<td headers="hivinter">Specific binding of HIV-1 Vif to Sp140 was identified using a yeast two-hybrid screen of a human lymphocyte cDNA library and verified by co-immunoprecipitation</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 19149577,12368356" href="/pubmed/19149577,12368356">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
<p class="withnote">
|
||
<a class="note" href="/genome/viruses/retroviruses/hiv-1/interactions/">Go to the HIV-1, Human Interaction Database </a>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
<div class="rprt-section gene-interactions">
|
||
<section class="rprt-section-header" id="interactions">
|
||
<h2 id="header-interactions">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-interactions .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Interactions</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Interactions" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<table summary="Gene Interaction" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/11262/data/interaction/',webserviceParams: 'p$l=Ajax&p$debugoutput=off', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th id="inter-prod">Products</th>
|
||
<th id="inter-interactant">Interactant</th>
|
||
<th id="inter-otherGene">Other Gene</th>
|
||
<th id="inter-compl">Complex</th>
|
||
<th id="inter-source">Source</th>
|
||
<th id="inter-pubs">Pubs</th>
|
||
<th id="inter-desc">Description</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody></tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-general-gene-info">
|
||
<section class="rprt-section-header" id="general-gene-info">
|
||
<h2 id="header-general-gene-info">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-gene-info .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">General gene information</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.General_Gene_Information" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
|
||
<div class="rprt-section-body" style="">
|
||
<div id="gene-markers">
|
||
<h3 id="markers">
|
||
<a class="jig-ncbitoggler">Markers</a>
|
||
</h3>
|
||
<div>
|
||
<ul class="marker odd">
|
||
<li class="marker">D2S172 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=46623%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=11262&link_uid=46623">UniSTS:46623</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">SHGC-34902 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=60450%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=11262&link_uid=60450">UniSTS:60450</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">D2S172 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=11070%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=11262&link_uid=11070">UniSTS:11070</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">SHGC-401 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=89459%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=11262&link_uid=89459">UniSTS:89459</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">RH18044 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=4588%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=11262&link_uid=4588">UniSTS:4588</a></li></ul></li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div></div>
|
||
|
||
<div class="infosec">
|
||
<h3 id="homology">
|
||
<a class="jig-ncbitoggler-open">Homology</a>
|
||
</h3>
|
||
<ul class="geneinfo-subsec">
|
||
<li>
|
||
<a href="/gene/11262/ortholog/" id="ncbi-ortholog-link">NCBI Orthologs</a>
|
||
</li>
|
||
<a href="https://www.orthodb.org/?ncbi=11262" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=8178" target="_blank">
|
||
Orthologs from OrthoDB
|
||
</a>
|
||
</ul>
|
||
</div>
|
||
|
||
<!--<component id="Gene_InfoPathway"/>-->
|
||
|
||
<div class="infosec info-comment" id="info-comment">
|
||
<h3 id="CloneNames">
|
||
<a class="jig-ncbitoggler-open">Clone Names</a>
|
||
</h3>
|
||
<ul class="geneinfo-subsec">
|
||
<li>MGC126440 </li>
|
||
</ul>
|
||
</div>
|
||
|
||
<div class="gene-ontology infosec">
|
||
<h3 id="gene-ontology">
|
||
<a class="jig-ncbitoggler-open">
|
||
<span>Gene Ontology</span>
|
||
</a>
|
||
<a target="_blank" href="http://www.ebi.ac.uk/GOA" class="g-ontology-src" title="Provided by GOA">Provided by GOA</a>
|
||
</h3>
|
||
<div class="ontology-tables">
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Function</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0003677">enables DNA binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-1-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0000981">enables DNA-binding transcription factor activity, RNA polymerase II-specific</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-2-0" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005515">enables protein binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
|
||
<div id="evidence-code-3-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/24267382,32911434" target="_blank" title="PubMed ID 24267382,32911434" ref="ordinalpos=1&ncbi_uid=11262&link_uid=24267382,32911434">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0008270">enables zinc ion binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-4-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Process</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0006952">involved_in defense response</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-1-1" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/8910577" target="_blank" title="PubMed ID 8910577" ref="ordinalpos=1&ncbi_uid=11262&link_uid=8910577">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0006357">involved_in regulation of transcription by RNA polymerase II</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-2-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-config="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Component</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0016605">located_in PML body</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-1-2" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0001650">located_in fibrillar center</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-2-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005739">located_in mitochondrion</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-3-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005634">is_active_in nucleus</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-4-2" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005634">located_in nucleus</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-5-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/25593309" target="_blank" title="PubMed ID 25593309" ref="ordinalpos=1&ncbi_uid=11262&link_uid=25593309">PubMed</a> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-general-protein-info">
|
||
<section class="rprt-section-header" id="general-protein-info">
|
||
<h2 id="header-general-protein-info">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-protein-info .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">General protein information</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.General_Protein_Information" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<dl>
|
||
<dt>Preferred Names</dt>
|
||
<dd>nuclear body protein SP140</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt>Names</dt>
|
||
<dd>lymphoid-restricted homolog of Sp100</dd>
|
||
<dd>lymphoid-specific SP100 homolog</dd>
|
||
<dd>nuclear autoantigen Sp-140</dd>
|
||
<dd>speckled 140 kDa</dd>
|
||
</dl>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-reference-sequences">
|
||
<section class="rprt-section-header" id="reference-sequences">
|
||
<h2 id="header-reference-sequences">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-reference-sequences .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">NCBI Reference Sequences (RefSeq)</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.NCBI_Reference_Sequences_RefS" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<p>
|
||
<span class="new-icon">NEW</span>
|
||
<strong>Try the new <a href="/datasets/tables/genes/?table_type=transcripts&ids=11262&utm_source=gene&utm_medium=referral&utm_campaign=refseq" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report." data-ga-category="refseq" data-ga-action="click_datasets_link" data-ga-label="transcript_table">Transcript table</a></strong>
|
||
</p>
|
||
<h3 class="genomerefseqs gene_std_toggler" id="refseqset-independent">
|
||
<a class="jig-ncbitoggler-open">RefSeqs maintained independently of Annotated
|
||
Genomes</a>
|
||
</h3>
|
||
<div class="genomerefseqs_slave">
|
||
<p class="desc"> These reference sequences exist independently of genome builds. <a href="#refseq-expl" id="expl-refseg">Explain</a></p>
|
||
<p id="refseq-expl"> These reference sequences are curated independently of the genome
|
||
annotation cycle, so their versions may not match the RefSeq versions in the current
|
||
genome build. Identify version mismatches by comparing the version of the RefSeq in
|
||
this section to the one reported in <a href="#geneGenomic regions, transcripts, and products">Genomic regions,
|
||
transcripts, and products</a> above. </p>
|
||
<h4 id="genomic-p93837680">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NG_051286.2 RefSeqGene</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>44587..132066</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NG_051286.2?from=44587&to=132066&report=genbank" ref="ordinalpos=1&ncbi_uid=11262&link_uid=NG_051286.2?from=44587&to=132066&report=genbank">GenBank</a>, <a href="/nuccore/NG_051286.2?from=44587&to=132066&report=fasta" ref="ordinalpos=1&ncbi_uid=11262&link_uid=NG_051286.2?from=44587&to=132066&report=fasta">FASTA</a>, <a href="/nuccore/NG_051286.2?from=31464&to=145187&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=11262&link_uid=NG_051286.2?from=31464&to=145187&report=graph&content=5">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="mrnaandproteins-p168353760">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001005176.3">NM_001005176.3</a> → <a href="/protein/NP_001005176.1">NP_001005176.1</a> nuclear body protein SP140 isoform 2</p>
|
||
<p>
|
||
<a href="/ipg/NP_001005176.1/" ref="ncbi_uid=11262">See identical proteins and their annotated locations for NP_001005176.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (2) lacks multiple 3' exons, and has an alternate 3' sequence, as compared to variant 1. The encoded isoform 2 is much shorter and has a distinct C-terminus, as compared to isoform 1.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AA741304, AK301267, BC070160">AA741304, AK301267, BC070160</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS33392.1">CCDS33392.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q13342" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q13342</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/B4DVW8" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">B4DVW8</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000362749.3" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">ENSP00000362749.3</a>, <a href="http://www.ensembl.org/id/ENST00000373645.3" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">ENST00000373645.3</a></dd>
|
||
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001005176.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281203">pfam03172</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">42</span> → <span class="cddto">135</span></dt>
|
||
<dd class="clearfix"> Sp100; Sp100 domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001278451.2">NM_001278451.2</a> → <a href="/protein/NP_001265380.1">NP_001265380.1</a> nuclear body protein SP140 isoform 3</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter compared to isoform 1.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC009949, BC105960, DC391925, U36499">AC009949, BC105960, DC391925, U36499</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS63150.1">CCDS63150.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000398210.3" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">ENSP00000398210.3</a>, <a href="http://www.ensembl.org/id/ENST00000420434.7" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">ENST00000420434.7</a></dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001265380.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99933">cd05501</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">730</span> → <span class="cddto">833</span></dt>
|
||
<dd class="clearfix"> Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=277096">cd15626</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">665</span> → <span class="cddto">706</span></dt>
|
||
<dd class="clearfix"> PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=279658">pfam01342</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">558</span> → <span class="cddto">633</span></dt>
|
||
<dd class="clearfix"> SAND; SAND domain</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281203">pfam03172</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">42</span> → <span class="cddto">135</span></dt>
|
||
<dd class="clearfix"> Sp100; Sp100 domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001278452.2">NM_001278452.2</a> → <a href="/protein/NP_001265381.1">NP_001265381.1</a> nuclear body protein SP140 isoform 4</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (4) lacks two alternate in-frame exons compared to variant 1. The resulting isoform (4) has the same N- and C-termini but is shorter compared to isoform 1.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC009949, BC105744, DC391925, U36499">AC009949, BC105744, DC391925, U36499</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS63151.1">CCDS63151.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000342096.6" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">ENSP00000342096.6</a>, <a href="http://www.ensembl.org/id/ENST00000343805.10" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">ENST00000343805.10</a></dd>
|
||
<dt class="clear"> Conserved Domains (5) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001265381.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99933">cd05501</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">697</span> → <span class="cddto">800</span></dt>
|
||
<dd class="clearfix"> Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=223003">PHA03169</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">202</span> → <span class="cddto">419</span></dt>
|
||
<dd class="clearfix"> PHA03169; hypothetical protein; Provisional</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=277096">cd15626</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">632</span> → <span class="cddto">673</span></dt>
|
||
<dd class="clearfix"> PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=279658">pfam01342</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">525</span> → <span class="cddto">600</span></dt>
|
||
<dd class="clearfix"> SAND; SAND domain</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281203">pfam03172</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">42</span> → <span class="cddto">135</span></dt>
|
||
<dd class="clearfix"> Sp100; Sp100 domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001278453.2">NM_001278453.2</a> → <a href="/protein/NP_001265382.1">NP_001265382.1</a> nuclear body protein SP140 isoform 5</p>
|
||
<p>
|
||
<a href="/ipg/NP_001265382.1/" ref="ncbi_uid=11262">See identical proteins and their annotated locations for NP_001265382.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (5) lacks three alternate in-frame exons and uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 1. The resulting isoform (5) has the same N- and C-termini but is shorter compared to isoform 1.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC009949, AC009950, DC391925, U36499, U63420">AC009949, AC009950, DC391925, U36499, U63420</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS63149.1">CCDS63149.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000393618.3" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">ENSP00000393618.3</a>, <a href="http://www.ensembl.org/id/ENST00000417495.7" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">ENST00000417495.7</a></dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001265382.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99933">cd05501</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">643</span> → <span class="cddto">746</span></dt>
|
||
<dd class="clearfix"> Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=277096">cd15626</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">578</span> → <span class="cddto">619</span></dt>
|
||
<dd class="clearfix"> PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=279658">pfam01342</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">471</span> → <span class="cddto">546</span></dt>
|
||
<dd class="clearfix"> SAND; SAND domain</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281203">pfam03172</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">42</span> → <span class="cddto">135</span></dt>
|
||
<dd class="clearfix"> Sp100; Sp100 domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_007237.5">NM_007237.5</a> → <a href="/protein/NP_009168.4">NP_009168.4</a> nuclear body protein SP140 isoform 1</p>
|
||
<p>
|
||
<a href="/ipg/NP_009168.4/" ref="ncbi_uid=11262">See identical proteins and their annotated locations for NP_009168.4</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC009949, AK301267, BC038091, BC105960, U36500">AC009949, AK301267, BC038091, BC105960, U36500</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS42831.1">CCDS42831.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/E7ESH9" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">E7ESH9</a>, <a href="https://www.uniprot.org/uniprot/E7EUR5" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">E7EUR5</a>, <a href="https://www.uniprot.org/uniprot/E9PFJ6" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">E9PFJ6</a>, <a href="https://www.uniprot.org/uniprot/Q0VGE5" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE5</a>, <a href="https://www.uniprot.org/uniprot/Q13341" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q13341</a>, <a href="https://www.uniprot.org/uniprot/Q13342" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q13342</a>, <a href="https://www.uniprot.org/uniprot/Q3KR17" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q3KR17</a>, <a href="https://www.uniprot.org/uniprot/Q4ZG66" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q4ZG66</a>, <a href="https://www.uniprot.org/uniprot/Q53TG1" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q53TG1</a>, <a href="https://www.uniprot.org/uniprot/Q6NSG4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q6NSG4</a>, <a href="https://www.uniprot.org/uniprot/Q92881" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q92881</a>, <a href="https://www.uniprot.org/uniprot/Q96TG3" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q96TG3</a></dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000375899.3" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">ENSP00000375899.3</a>, <a href="http://www.ensembl.org/id/ENST00000392045.8" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">ENST00000392045.8</a></dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_009168.4">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99933">cd05501</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">757</span> → <span class="cddto">860</span></dt>
|
||
<dd class="clearfix"> Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=277096">cd15626</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">692</span> → <span class="cddto">733</span></dt>
|
||
<dd class="clearfix"> PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=279658">pfam01342</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">585</span> → <span class="cddto">660</span></dt>
|
||
<dd class="clearfix"> SAND; SAND domain</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281203">pfam03172</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">42</span> → <span class="cddto">135</span></dt>
|
||
<dd class="clearfix"> Sp100; Sp100 domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
<h3 class="genomerefseqs gene_std_toggler" id="annotatedrefseq-title">
|
||
<a class="jig-ncbitoggler-open">RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08</a>
|
||
</h3>
|
||
<div class="genomerefseqs_slave">
|
||
<p class="desc"> The following sections contain reference sequences that belong to a
|
||
specific genome build. <a href="#" id="expl-genomes">Explain</a></p>
|
||
<p id="expl-genomes-desc" style="display:none">This section includes genomic Reference
|
||
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
|
||
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
|
||
assemblies. Model RNAs and proteins are also reported here.</p>
|
||
<h3 id="refseq-sequencedescription-p28509792">Reference GRCh38.p14 Primary Assembly</h3>
|
||
<h4 id="genomic-p28509792">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NC_000002.12 Reference GRCh38.p14 Primary Assembly</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>230186151..230316571</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NC_000002.12?from=230186151&to=230316571&report=genbank" ref="ordinalpos=1&ncbi_uid=11262&link_uid=NC_000002.12?from=230186151&to=230316571&report=genbank">GenBank</a>, <a href="/nuccore/NC_000002.12?from=230186151&to=230316571&report=fasta" ref="ordinalpos=1&ncbi_uid=11262&link_uid=NC_000002.12?from=230186151&to=230316571&report=fasta">FASTA</a>, <a href="/nuccore/NC_000002.12?from=230166587&to=230336133&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=11262&link_uid=NC_000002.12?from=230166587&to=230336133&report=graph&content=5">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="mrnaandproteins-p46971488">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047443073.1">XM_047443073.1</a> → <a href="/protein/XP_047299029.1">XP_047299029.1</a> nuclear body protein SP140 isoform X7</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011510517.4">XM_011510517.4</a> → <a href="/protein/XP_011508819.1">XP_011508819.1</a> nuclear body protein SP140 isoform X7</p>
|
||
<p>
|
||
<a href="/ipg/XP_011508819.1/" ref="ncbi_uid=11262">See identical proteins and their annotated locations for XP_011508819.1</a>
|
||
</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011508819.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99933">cd05501</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">737</span> → <span class="cddto">840</span></dt>
|
||
<dd class="clearfix"> Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=277096">cd15626</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">672</span> → <span class="cddto">713</span></dt>
|
||
<dd class="clearfix"> PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=279658">pfam01342</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">565</span> → <span class="cddto">640</span></dt>
|
||
<dd class="clearfix"> SAND; SAND domain</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281203">pfam03172</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">22</span> → <span class="cddto">115</span></dt>
|
||
<dd class="clearfix"> Sp100; Sp100 domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_006712223.4">XM_006712223.4</a> → <a href="/protein/XP_006712286.1">XP_006712286.1</a> nuclear body protein SP140 isoform X1</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/B4DVW8" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">B4DVW8</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_006712286.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=277096">cd15626</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">692</span> → <span class="cddto">733</span></dt>
|
||
<dd class="clearfix"> PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=279658">pfam01342</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">585</span> → <span class="cddto">660</span></dt>
|
||
<dd class="clearfix"> SAND; SAND domain</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281203">pfam03172</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">42</span> → <span class="cddto">135</span></dt>
|
||
<dd class="clearfix"> Sp100; Sp100 domain</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=295360">cl02556</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">757</span> → <span class="cddto">838</span></dt>
|
||
<dd class="clearfix"> Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047443077.1">XM_047443077.1</a> → <a href="/protein/XP_047299033.1">XP_047299033.1</a> nuclear body protein SP140 isoform X21</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/B4DVW8" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">B4DVW8</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011510518.3">XM_011510518.3</a> → <a href="/protein/XP_011508820.1">XP_011508820.1</a> nuclear body protein SP140 isoform X7</p>
|
||
<p>
|
||
<a href="/ipg/XP_011508820.1/" ref="ncbi_uid=11262">See identical proteins and their annotated locations for XP_011508820.1</a>
|
||
</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011508820.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99933">cd05501</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">737</span> → <span class="cddto">840</span></dt>
|
||
<dd class="clearfix"> Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=277096">cd15626</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">672</span> → <span class="cddto">713</span></dt>
|
||
<dd class="clearfix"> PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=279658">pfam01342</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">565</span> → <span class="cddto">640</span></dt>
|
||
<dd class="clearfix"> SAND; SAND domain</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281203">pfam03172</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">22</span> → <span class="cddto">115</span></dt>
|
||
<dd class="clearfix"> Sp100; Sp100 domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011510516.2">XM_011510516.2</a> → <a href="/protein/XP_011508818.1">XP_011508818.1</a> nuclear body protein SP140 isoform X5</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011508818.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99933">cd05501</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">748</span> → <span class="cddto">851</span></dt>
|
||
<dd class="clearfix"> Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=277096">cd15626</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">692</span> → <span class="cddto">726</span></dt>
|
||
<dd class="clearfix"> PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=279658">pfam01342</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">585</span> → <span class="cddto">660</span></dt>
|
||
<dd class="clearfix"> SAND; SAND domain</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281203">pfam03172</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">42</span> → <span class="cddto">135</span></dt>
|
||
<dd class="clearfix"> Sp100; Sp100 domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011510515.2">XM_011510515.2</a> → <a href="/protein/XP_011508817.1">XP_011508817.1</a> nuclear body protein SP140 isoform X3</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011508817.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99933">cd05501</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">751</span> → <span class="cddto">854</span></dt>
|
||
<dd class="clearfix"> Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=277096">cd15626</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">686</span> → <span class="cddto">727</span></dt>
|
||
<dd class="clearfix"> PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=279658">pfam01342</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">579</span> → <span class="cddto">654</span></dt>
|
||
<dd class="clearfix"> SAND; SAND domain</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281203">pfam03172</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">42</span> → <span class="cddto">135</span></dt>
|
||
<dd class="clearfix"> Sp100; Sp100 domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_005246254.3">XM_005246254.3</a> → <a href="/protein/XP_005246311.1">XP_005246311.1</a> nuclear body protein SP140 isoform X13</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_005246311.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99933">cd05501</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">723</span> → <span class="cddto">826</span></dt>
|
||
<dd class="clearfix"> Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=277096">cd15626</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">658</span> → <span class="cddto">699</span></dt>
|
||
<dd class="clearfix"> PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=279658">pfam01342</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">551</span> → <span class="cddto">626</span></dt>
|
||
<dd class="clearfix"> SAND; SAND domain</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281203">pfam03172</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">42</span> → <span class="cddto">135</span></dt>
|
||
<dd class="clearfix"> Sp100; Sp100 domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011510519.2">XM_011510519.2</a> → <a href="/protein/XP_011508821.1">XP_011508821.1</a> nuclear body protein SP140 isoform X9</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011508821.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99933">cd05501</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">730</span> → <span class="cddto">833</span></dt>
|
||
<dd class="clearfix"> Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=277096">cd15626</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">665</span> → <span class="cddto">706</span></dt>
|
||
<dd class="clearfix"> PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=279658">pfam01342</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">558</span> → <span class="cddto">633</span></dt>
|
||
<dd class="clearfix"> SAND; SAND domain</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281203">pfam03172</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">42</span> → <span class="cddto">135</span></dt>
|
||
<dd class="clearfix"> Sp100; Sp100 domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_005246256.3">XM_005246256.3</a> → <a href="/protein/XP_005246313.1">XP_005246313.1</a> nuclear body protein SP140 isoform X20</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_005246313.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99933">cd05501</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">696</span> → <span class="cddto">799</span></dt>
|
||
<dd class="clearfix"> Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=277096">cd15626</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">631</span> → <span class="cddto">672</span></dt>
|
||
<dd class="clearfix"> PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=279658">pfam01342</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">524</span> → <span class="cddto">599</span></dt>
|
||
<dd class="clearfix"> SAND; SAND domain</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281203">pfam03172</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">42</span> → <span class="cddto">135</span></dt>
|
||
<dd class="clearfix"> Sp100; Sp100 domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047443078.1">XM_047443078.1</a> → <a href="/protein/XP_047299034.1">XP_047299034.1</a> nuclear body protein SP140 isoform X24</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_005246255.3">XM_005246255.3</a> → <a href="/protein/XP_005246312.1">XP_005246312.1</a> nuclear body protein SP140 isoform X16</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/B4DVW8" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">B4DVW8</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_005246312.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99933">cd05501</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">707</span> → <span class="cddto">810</span></dt>
|
||
<dd class="clearfix"> Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=277096">cd15626</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">642</span> → <span class="cddto">683</span></dt>
|
||
<dd class="clearfix"> PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=279658">pfam01342</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">535</span> → <span class="cddto">610</span></dt>
|
||
<dd class="clearfix"> SAND; SAND domain</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281203">pfam03172</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">42</span> → <span class="cddto">135</span></dt>
|
||
<dd class="clearfix"> Sp100; Sp100 domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047443076.1">XM_047443076.1</a> → <a href="/protein/XP_047299032.1">XP_047299032.1</a> nuclear body protein SP140 isoform X19</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/B4DVW8" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">B4DVW8</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_017003252.2">XM_017003252.2</a> → <a href="/protein/XP_016858741.1">XP_016858741.1</a> nuclear body protein SP140 isoform X28</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_005246253.3">XM_005246253.3</a> → <a href="/protein/XP_005246310.1">XP_005246310.1</a> nuclear body protein SP140 isoform X8</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (5) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_005246310.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99933">cd05501</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">731</span> → <span class="cddto">834</span></dt>
|
||
<dd class="clearfix"> Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=223003">PHA03169</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">202</span> → <span class="cddto">453</span></dt>
|
||
<dd class="clearfix"> PHA03169; hypothetical protein; Provisional</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=277096">cd15626</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">666</span> → <span class="cddto">707</span></dt>
|
||
<dd class="clearfix"> PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=279658">pfam01342</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">559</span> → <span class="cddto">634</span></dt>
|
||
<dd class="clearfix"> SAND; SAND domain</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281203">pfam03172</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">42</span> → <span class="cddto">135</span></dt>
|
||
<dd class="clearfix"> Sp100; Sp100 domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_017003240.2">XM_017003240.2</a> → <a href="/protein/XP_016858729.1">XP_016858729.1</a> nuclear body protein SP140 isoform X12</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_017003249.2">XM_017003249.2</a> → <a href="/protein/XP_016858738.1">XP_016858738.1</a> nuclear body protein SP140 isoform X26</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_005246252.3">XM_005246252.3</a> → <a href="/protein/XP_005246309.1">XP_005246309.1</a> nuclear body protein SP140 isoform X2</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_005246309.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99933">cd05501</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">754</span> → <span class="cddto">857</span></dt>
|
||
<dd class="clearfix"> Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=277096">cd15626</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">689</span> → <span class="cddto">730</span></dt>
|
||
<dd class="clearfix"> PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=279658">pfam01342</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">582</span> → <span class="cddto">657</span></dt>
|
||
<dd class="clearfix"> SAND; SAND domain</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281203">pfam03172</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">42</span> → <span class="cddto">135</span></dt>
|
||
<dd class="clearfix"> Sp100; Sp100 domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047443072.1">XM_047443072.1</a> → <a href="/protein/XP_047299028.1">XP_047299028.1</a> nuclear body protein SP140 isoform X6</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_017003239.2">XM_017003239.2</a> → <a href="/protein/XP_016858728.1">XP_016858728.1</a> nuclear body protein SP140 isoform X4</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_017003243.2">XM_017003243.2</a> → <a href="/protein/XP_016858732.1">XP_016858732.1</a> nuclear body protein SP140 isoform X15</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047443074.1">XM_047443074.1</a> → <a href="/protein/XP_047299030.1">XP_047299030.1</a> nuclear body protein SP140 isoform X11</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_017003248.2">XM_017003248.2</a> → <a href="/protein/XP_016858737.1">XP_016858737.1</a> nuclear body protein SP140 isoform X23</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047443079.1">XM_047443079.1</a> → <a href="/protein/XP_047299035.1">XP_047299035.1</a> nuclear body protein SP140 isoform X25</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_017003245.2">XM_017003245.2</a> → <a href="/protein/XP_016858734.1">XP_016858734.1</a> nuclear body protein SP140 isoform X17</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/B4DVW8" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">B4DVW8</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011510520.2">XM_011510520.2</a> → <a href="/protein/XP_011508822.1">XP_011508822.1</a> nuclear body protein SP140 isoform X10</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011508822.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=99933">cd05501</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">728</span> → <span class="cddto">831</span></dt>
|
||
<dd class="clearfix"> Bromo_SP100C_like; Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=277096">cd15626</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">663</span> → <span class="cddto">704</span></dt>
|
||
<dd class="clearfix"> PHD_SP110_140; PHD finger found in the Sp100/Sp140 family of nuclear body components</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=279658">pfam01342</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">556</span> → <span class="cddto">631</span></dt>
|
||
<dd class="clearfix"> SAND; SAND domain</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=281203">pfam03172</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">42</span> → <span class="cddto">135</span></dt>
|
||
<dd class="clearfix"> Sp100; Sp100 domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_017003242.2">XM_017003242.2</a> → <a href="/protein/XP_016858731.1">XP_016858731.1</a> nuclear body protein SP140 isoform X14</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_017003247.2">XM_017003247.2</a> → <a href="/protein/XP_016858736.1">XP_016858736.1</a> nuclear body protein SP140 isoform X22</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_017003246.2">XM_017003246.2</a> → <a href="/protein/XP_016858735.1">XP_016858735.1</a> nuclear body protein SP140 isoform X18</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_017003250.2">XM_017003250.2</a> → <a href="/protein/XP_016858739.1">XP_016858739.1</a> nuclear body protein SP140 isoform X27</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047443080.1">XM_047443080.1</a> → <a href="/protein/XP_047299036.1">XP_047299036.1</a> nuclear body protein SP140 isoform X29</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047443081.1">XM_047443081.1</a> → <a href="/protein/XP_047299037.1">XP_047299037.1</a> nuclear body protein SP140 isoform X31</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_017003253.2">XM_017003253.2</a> → <a href="/protein/XP_016858742.1">XP_016858742.1</a> nuclear body protein SP140 isoform X30</p>
|
||
<dl></dl>
|
||
</li>
|
||
</ol>
|
||
<h3 id="refseq-sequencedescription-p144404448">Alternate T2T-CHM13v2.0</h3>
|
||
<h4 id="genomic-p144404448">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NC_060926.1 Alternate T2T-CHM13v2.0</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>230669263..230808985</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NC_060926.1?from=230669263&to=230808985&report=genbank" ref="ordinalpos=1&ncbi_uid=11262&link_uid=NC_060926.1?from=230669263&to=230808985&report=genbank">GenBank</a>, <a href="/nuccore/NC_060926.1?from=230669263&to=230808985&report=fasta" ref="ordinalpos=1&ncbi_uid=11262&link_uid=NC_060926.1?from=230669263&to=230808985&report=fasta">FASTA</a>, <a href="/nuccore/NC_060926.1?from=230648304&to=230829942&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=11262&link_uid=NC_060926.1?from=230648304&to=230829942&report=graph&content=5">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="mrnaandproteins-p90262848">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340304.1">XM_054340304.1</a> → <a href="/protein/XP_054196279.1">XP_054196279.1</a> nuclear body protein SP140 isoform X7</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340302.1">XM_054340302.1</a> → <a href="/protein/XP_054196277.1">XP_054196277.1</a> nuclear body protein SP140 isoform X7</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340296.1">XM_054340296.1</a> → <a href="/protein/XP_054196271.1">XP_054196271.1</a> nuclear body protein SP140 isoform X1</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/B4DVW8" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">B4DVW8</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340318.1">XM_054340318.1</a> → <a href="/protein/XP_054196293.1">XP_054196293.1</a> nuclear body protein SP140 isoform X21</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340303.1">XM_054340303.1</a> → <a href="/protein/XP_054196278.1">XP_054196278.1</a> nuclear body protein SP140 isoform X7</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340300.1">XM_054340300.1</a> → <a href="/protein/XP_054196275.1">XP_054196275.1</a> nuclear body protein SP140 isoform X5</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340298.1">XM_054340298.1</a> → <a href="/protein/XP_054196273.1">XP_054196273.1</a> nuclear body protein SP140 isoform X3</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340310.1">XM_054340310.1</a> → <a href="/protein/XP_054196285.1">XP_054196285.1</a> nuclear body protein SP140 isoform X13</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340306.1">XM_054340306.1</a> → <a href="/protein/XP_054196281.1">XP_054196281.1</a> nuclear body protein SP140 isoform X9</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340317.1">XM_054340317.1</a> → <a href="/protein/XP_054196292.1">XP_054196292.1</a> nuclear body protein SP140 isoform X20</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340321.1">XM_054340321.1</a> → <a href="/protein/XP_054196296.1">XP_054196296.1</a> nuclear body protein SP140 isoform X24</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340313.1">XM_054340313.1</a> → <a href="/protein/XP_054196288.1">XP_054196288.1</a> nuclear body protein SP140 isoform X16</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/B4DVW8" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">B4DVW8</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340316.1">XM_054340316.1</a> → <a href="/protein/XP_054196291.1">XP_054196291.1</a> nuclear body protein SP140 isoform X19</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/B4DVW8" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">B4DVW8</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340325.1">XM_054340325.1</a> → <a href="/protein/XP_054196300.1">XP_054196300.1</a> nuclear body protein SP140 isoform X28</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340305.1">XM_054340305.1</a> → <a href="/protein/XP_054196280.1">XP_054196280.1</a> nuclear body protein SP140 isoform X8</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340309.1">XM_054340309.1</a> → <a href="/protein/XP_054196284.1">XP_054196284.1</a> nuclear body protein SP140 isoform X12</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340323.1">XM_054340323.1</a> → <a href="/protein/XP_054196298.1">XP_054196298.1</a> nuclear body protein SP140 isoform X26</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340297.1">XM_054340297.1</a> → <a href="/protein/XP_054196272.1">XP_054196272.1</a> nuclear body protein SP140 isoform X2</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340301.1">XM_054340301.1</a> → <a href="/protein/XP_054196276.1">XP_054196276.1</a> nuclear body protein SP140 isoform X6</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340299.1">XM_054340299.1</a> → <a href="/protein/XP_054196274.1">XP_054196274.1</a> nuclear body protein SP140 isoform X4</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340312.1">XM_054340312.1</a> → <a href="/protein/XP_054196287.1">XP_054196287.1</a> nuclear body protein SP140 isoform X15</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340308.1">XM_054340308.1</a> → <a href="/protein/XP_054196283.1">XP_054196283.1</a> nuclear body protein SP140 isoform X11</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340320.1">XM_054340320.1</a> → <a href="/protein/XP_054196295.1">XP_054196295.1</a> nuclear body protein SP140 isoform X23</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340322.1">XM_054340322.1</a> → <a href="/protein/XP_054196297.1">XP_054196297.1</a> nuclear body protein SP140 isoform X25</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340314.1">XM_054340314.1</a> → <a href="/protein/XP_054196289.1">XP_054196289.1</a> nuclear body protein SP140 isoform X17</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/B4DVW8" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">B4DVW8</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340307.1">XM_054340307.1</a> → <a href="/protein/XP_054196282.1">XP_054196282.1</a> nuclear body protein SP140 isoform X10</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340311.1">XM_054340311.1</a> → <a href="/protein/XP_054196286.1">XP_054196286.1</a> nuclear body protein SP140 isoform X14</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340319.1">XM_054340319.1</a> → <a href="/protein/XP_054196294.1">XP_054196294.1</a> nuclear body protein SP140 isoform X22</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340315.1">XM_054340315.1</a> → <a href="/protein/XP_054196290.1">XP_054196290.1</a> nuclear body protein SP140 isoform X18</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340324.1">XM_054340324.1</a> → <a href="/protein/XP_054196299.1">XP_054196299.1</a> nuclear body protein SP140 isoform X27</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q0VGE4" ref="itool=Gene_FullReport&PrId=5380&uid=11262&nlmid=&db=gene">Q0VGE4</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340326.1">XM_054340326.1</a> → <a href="/protein/XP_054196301.1">XP_054196301.1</a> nuclear body protein SP140 isoform X29</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340328.1">XM_054340328.1</a> → <a href="/protein/XP_054196303.1">XP_054196303.1</a> nuclear body protein SP140 isoform X31</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054340327.1">XM_054340327.1</a> → <a href="/protein/XP_054196302.1">XP_054196302.1</a> nuclear body protein SP140 isoform X30</p>
|
||
<dl></dl>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-related-sequences">
|
||
<section class="rprt-section-header" id="related-sequences">
|
||
<h2 id="header-related-sequences">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-related-sequences .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Related sequences</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Related_Sequences" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<table id="proteinTblId" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/11262/data/related-sequences/',webserviceParams: 'p$l=Ajax', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th colspan="2" id="rs-nucleo">Nucleotide</th>
|
||
<th rowspan="2" id="rs-protein">Protein</th>
|
||
</tr>
|
||
<tr>
|
||
<th id="rs-heading">Heading</th>
|
||
<th id="rs-heading-acc">Accession and Version</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody></tbody>
|
||
</table>
|
||
<table id="proteinTblId" class="jig-ncbigrid" data-jigconfig="isPageable:true, pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th class="proteinTblTh" rowspan="2" id="rs-prot-acc">Protein Accession</th>
|
||
<th class="proteinTblTh" colspan="2" id="rs-link">Links</th>
|
||
</tr>
|
||
<tr>
|
||
<th id="rs-genepept">GenPept Link</th>
|
||
<th id="rs-uniprot">UniProtKB Link</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="rs-prot-acc">Q13342.2</td>
|
||
<td headers="rs-link rs-genepept">
|
||
<a href="/protein/218511671" ref="ordinalpos=1&ncbi_uid=11262&link_uid=218511671">GenPept</a>
|
||
</td>
|
||
<td>
|
||
<a href="https://www.uniprot.org/uniprot/Q13342">UniProtKB/Swiss-Prot:Q13342</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-additional-links">
|
||
|
||
<section class="rprt-section-header" id="additional-links"><h2 id="header-additional-links"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-additional-links .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Additional links</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Additional_Links" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
|
||
|
||
<div class="rprt-section-body" style="">
|
||
|
||
|
||
<h3 class="withnote" id="genelinkout">
|
||
<a class="jig-ncbitoggler">Gene LinkOut</a>
|
||
</h3><div>
|
||
<p>The following <a href="https://www.ncbi.nlm.nih.gov/projects/linkout/index.html">LinkOut</a> resources are supplied by external providers. These providers are responsible for maintaining the links. </p>
|
||
<div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Chemical Information</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Interologous Interaction Database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://ophid.utoronto.ca/redirect/ncbi/human?proteins=11262" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=7911">
|
||
<span>Interologous Interaction Database</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>MilliporeSigma</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.sigmaaldrich.com/catalog/genes/SP140?lang=en&region=US" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=9978">
|
||
<span>Sp140 products</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Molecular Biology Databases</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Bgee database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.bgee.org/gene/ENSG00000079263" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=10418">
|
||
<span>SP140 gene expression</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>BioGPS</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://biogps.org/gene/11262/" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=5059">
|
||
<span>BioGPS</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>BioGRID Open Repository of CRISPR Screens (ORCS)</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://orcs.thebiogrid.org/Gene/11262" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=10164">
|
||
<span>BioGRID CRISPR Screen Phenotypes (16 hits/1388 screens)</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>CTD: Comparative Toxicogenomics Database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://ctdbase.org/detail.go?type=gene&acc=11262" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=7845">
|
||
<span>CTD: Comparative Toxicogenomics Database - SP140</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Domain Mapping of Disease Mutations</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://bioinf.umbc.edu/DMDM/gene_prot_page.php?id=11262" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=7642">
|
||
<span>SP140</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>GlyGen glycoinformatics resource</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://glygen.org/protein/Q13342" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=10227">
|
||
<span>GlyGen glycoinformatics resource</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Guide to Pharmacology</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=2779" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=8191">
|
||
<span>SP140 nuclear body protein gene</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Human eFP Browser</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Skeletal_Immune_Digestive&modeInput=Absolute&primaryGene=11262" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Reproductive&modeInput=Absolute&primaryGene=11262" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Nervous&modeInput=Absolute&primaryGene=11262" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li>Ingenuity Pathways Analysis</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://partnersolution.ingenuity.com/?cid=97ae3f91eab87a&p1=Entrez&p2=GV&s=&ipaUri=%2Fpa%2Fapi%2Fv2%2Fgeneview%3Fapplicationname%3DEntrez%26geneId%3D11262%26geneidtype%3Dentrezgene" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=5628">
|
||
<span>Ingenuity Pathways Analysis</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>InnateDB</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.innatedb.com/getGeneCard.do?id=82911" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=7894">
|
||
<span>InnateDB</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>InterMine</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.humanmine.org/humanmine/search?keyword=ENSG00000079263" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=9169">
|
||
<span>InterMine</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Kyoto Encyclopedia of Genes and Genomes</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.genome.jp/dbget-bin/www_bget?hsa:11262" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=5174">
|
||
<span>Kyoto Encyclopedia of Genes and Genomes</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>OMA Browser: Orthologous MAtrix</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN67374/" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN67375/" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN67372/" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>OrthoDB catalog of orthologs</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.orthodb.org/?ncbi=11262" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=8178">
|
||
<span>Orthologs</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>PhosphoSitePlus</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.phosphosite.org/entrezGeneIdAction.action?id=11262" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=7987">
|
||
<span>PhosphoSitePlus® - comprehensive post-translational modification resource</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>The Weizmann Institute of Science GeneCards and MalaCards databases</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=SP140" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=8598">
|
||
<span>GeneCard for SP140</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Research Materials</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="order-rsc"></span>Addgene Non-profit plasmid repository</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://addgene.org//browse/gene/11262" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=5304">
|
||
<span>Get Plasmids - Addgene</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>Bio-Techne</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/sp140/proteins-enzymes?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=proteins" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>SP140 Proteins</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/sp140/lysates?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=lysates" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>SP140 Lysates</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/sp140/antibodies?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=antibodies" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>SP140 Antibodies</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li>ExactAntigen/Labome</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.labome.com/gene/human/SP140-antibody.html" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=5753">
|
||
<span>reagents</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GenScript latest version of gene cDNA ORF Clone</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.genscript.com/gene/11262" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=8012">
|
||
<span>GenScript latest version of gene cDNA ORF Clone</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GeneCopoeia Inc.</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=26&field=5&key=11262" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order TALEN/CRISPR clones</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?tax_id=9606&field=5&prt=16&key=11262" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order miRNA target clones</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=1&field=5&key=11262" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order full-length ORF clone</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>OriGene</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.origene.com/search?q=SP140" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=7994">
|
||
<span>Order SP140 cDNA clone/Protein/Antibody/RNAi</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Tools</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>GeneMANIA</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://genemania.org/link?o=9606&g=11262" ref="itool=Gene_FullReport&uid=11262&nlmid=&db=gene&log$=linkoutlink&PrId=7529">
|
||
<span>GeneMANIA</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="urls-in-genombrowser" style="display:none">
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div><input type="hidden" class="section_status_input" name="status_checked" id="status_checked" value="" /><input type="hidden" class="section_status_input" name="status_open" id="status_open" value="summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links" /><input type="hidden" class="section_status_input" name="status_exist" id="status_exist" value="summary,context,region,expression,bibliography,phenotypes,variation,hiv,interactions,geneInfo,proteinInfo,refSeq,related,links" /><input type="hidden" class="section_status_input" name="status_closed" id="status_closed" value="" /><meta name="status_checked" content="" class="meta_section_status" /><meta name="status_open" content="summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links" class="meta_section_status" /><meta name="status_exist" content="summary,context,region,expression,bibliography,phenotypes,variation,hiv,interactions,geneInfo,proteinInfo,refSeq,related,links" class="meta_section_status" /><meta name="status_closed" content="" class="meta_section_status" /><script type="text/javascript">
|
||
|
||
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|
||
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|
||
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|
||
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|
||
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|
||
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|
||
|
||
|
||
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|
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|
||
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||
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||
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|
||
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|
||
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|
||
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|
||
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|
||
|
||
|
||
var __ncbi_sg_pingCallbacks_render_gene = function (data, evtObj, type) {
|
||
// data looks like {jsevent: "click", "link_id": "foo", ...}
|
||
// evtObj is the JS event object
|
||
// type is either "stat" (for applog) or "ga"
|
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|
||
|
||
return extraData;
|
||
|
||
}
|
||
}
|
||
|
||
|
||
</script></div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last" id="sidebar_tabular">
|
||
<!-- sidebar close/hide button-->
|
||
<div class="ui-helper-clearfix">
|
||
<a href="#" id="sidecontent_2_pullout" style="float:right;" class="sidecontentpullout_local collapse_button"><span>Hide sidebar >></span></a>
|
||
</div>
|
||
<!-- end sidebar close/hide button-->
|
||
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div id="gene-sidebar">
|
||
<div>
|
||
<div class="portlet brieflink dis-table-of-contents">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Table of contents</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_TableOfContents" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li class="">
|
||
<a href="#summary">Summary</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#genomic-context">Genomic context</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#genomic-regions-transcripts-products">Genomic regions, transcripts, and products</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#gene-expression">Expression</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#bibliography">Bibliography</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#phenotypes">Phenotypes</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#variation">Variation</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#HIV-1-interactions">HIV-1 interactions</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#interactions">Interactions</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#general-gene-info">General gene information</a>
|
||
<div class="subsection-links"><a href="#gene-markers">Markers</a>, <a href="#CloneNames">Clone Names</a>, <a href="#homology">Homology</a>, <a href="#gene-ontology">Gene Ontology</a></div>
|
||
</li>
|
||
<li class="">
|
||
<a href="#general-protein-info">General protein information</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#reference-sequences">NCBI Reference Sequences (RefSeq)</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#related-sequences">Related sequences</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#additional-links">Additional links</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-genomesbrowser brieflink dis-genomesbrowser">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Genome Browsers</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GenomeBrowsers.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_GenomeBrowsers" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GenomeBrowsers.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="#">Loading...</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet dis-related-info brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related information</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="discovery_db_links" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content DiscoveryDbLinks">
|
||
<ul>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clone/order/gene/11262" ref="log$=recordlinks">Order cDNA clone</a>
|
||
<div class="brieflinkpop offscreen_noflow">Order cDNA clone</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/structure?LinkName=gene_structure&from_uid=11262" ref="log$=recordlinks">3D structures</a>
|
||
<div class="brieflinkpop offscreen_noflow">3D structure of a gene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_alltarget_list&from_uid=11262" ref="log$=recordlinks">BioAssay by Target (List)</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioAssays related to the gene by protein target or RNAi target</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="//pubchem.ncbi.nlm.nih.gov/assay/bioactivity.html?geneid=11262" ref="log$=recordlinks">BioAssay by Target (Summary)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Summarized PubChem Data on the gene, showing the active data by default</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_target&from_uid=11262" ref="log$=recordlinks">BioAssay, by Gene target</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem BioAssays done on the Gene target</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_rnai_active&from_uid=11262" ref="log$=recordlinks">BioAssays, RNAi Target, Active</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioAssays that contain the gene as the target of a RNAi reagent, which is identified as a hit in a RNAi screening and flagged as "active" in the corresponding BioAssay record</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_rnai&from_uid=11262" ref="log$=recordlinks">BioAssays, RNAi Target, Tested</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioAssays that contain the gene as the target of a RNAi reagent</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/bioproject?LinkName=gene_bioproject&from_uid=11262" ref="log$=recordlinks">BioProjects</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioProjects related to a gene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/CCDS/CcdsBrowse.cgi?REQUEST=GENEID&DATA=11262" ref="log$=recordlinks">CCDS</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to CCDS</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar&from_uid=11262" ref="log$=recordlinks">ClinVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/cdd?LinkName=gene_cdd&from_uid=11262" ref="log$=recordlinks">Conserved Domains</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related CDD</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/dbvar?LinkName=gene_dbvar&from_uid=11262" ref="log$=recordlinks">dbVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link from Gene to dbVar</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc&from_uid=11262" ref="log$=recordlinks">Full text in PMC</a>
|
||
<div class="brieflinkpop offscreen_noflow">PMC links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc_nucleotide&from_uid=11262" ref="log$=recordlinks">Full text in PMC_nucleotide</a>
|
||
<div class="brieflinkpop offscreen_noflow">Full text in PubMedCentral identified from shared sequence links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/sparcle?LinkName=gene_sparcle&from_uid=11262" ref="log$=recordlinks">Functional Class</a>
|
||
<div class="brieflinkpop offscreen_noflow">Functional class of the sequence domain architecture</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gap?LinkName=gene_gap&from_uid=11262" ref="log$=recordlinks">GAP</a>
|
||
<div class="brieflinkpop offscreen_noflow">GAP Links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_neighbors&from_uid=11262" ref="log$=recordlinks">Gene neighbors</a>
|
||
<div class="brieflinkpop offscreen_noflow">Overlapping genes and two nearest non-overlapping genes on either side</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_h3k4me3&from_uid=11262" ref="log$=recordlinks">Genes with a similar H3K4me3 profile</a>
|
||
<div class="brieflinkpop offscreen_noflow">Genes with a similar profile of promoter-activating H3K4me3 modifications across several tissue types</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/genome?LinkName=gene_genome&from_uid=11262" ref="log$=recordlinks">Genome</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Genome</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/geoprofiles?LinkName=gene_geoprofiles&from_uid=11262" ref="log$=recordlinks">GEO Profiles</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related GEO</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests/?term=11262[geneid]" ref="log$=recordlinks">GTR</a>
|
||
<div class="brieflinkpop offscreen_noflow">Tests for this gene in the NIH Genetic Testing Registry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/homologene?LinkName=gene_homologene&from_uid=11262" ref="log$=recordlinks">HomoloGene</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related HomoloGene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore&from_uid=11262" ref="log$=recordlinks">Nucleotide</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related Nucleotide entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/omim?LinkName=gene_omim&from_uid=11262" ref="log$=recordlinks">OMIM</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related OMIM entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/probe?LinkName=gene_probe&from_uid=11262" ref="log$=recordlinks">Probe</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Probe entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein&from_uid=11262" ref="log$=recordlinks">Protein</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related protein entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pccompound?LinkName=gene_pccompound&from_uid=11262" ref="log$=recordlinks">PubChem Compound</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem Compounds</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcsubstance?LinkName=gene_pcsubstance&from_uid=11262" ref="log$=recordlinks">PubChem Substance</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem Substances</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed&from_uid=11262" ref="log$=recordlinks">PubMed</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related PubMed entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_rif&from_uid=11262" ref="log$=recordlinks">PubMed (GeneRIF)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related PubMed article from GeneRIFs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_citedinomim&from_uid=11262" ref="log$=recordlinks">PubMed (OMIM)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Gene links to PubMed derived from omim_pubmed_cited links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_pmc_nucleotide&from_uid=11262" ref="log$=recordlinks">PubMed(nucleotide/PMC)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Citations in PubMed identified from shared sequence and PMC links.</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein_refseq&from_uid=11262" ref="log$=recordlinks">RefSeq Proteins</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Protein RefSeqs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore_refseqrna&from_uid=11262" ref="log$=recordlinks">RefSeq RNAs</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeq RNAs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore/2310182836?report=graph" ref="log$=recordlinks">RefSeqGene</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeqGenes</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar_specific&from_uid=11262" ref="log$=recordlinks">Related gene-specific medical variations</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/snp?LinkName=gene_snp&from_uid=11262" ref="log$=recordlinks">SNP</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related SNP records</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/taxonomy?LinkName=gene_taxonomy&from_uid=11262" ref="log$=recordlinks">Taxonomy</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related taxonomy entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/variation/view/?q=11262[geneid]" ref="log$=recordlinks">Variation Viewer</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Variants</div>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet dis-links-to-other-res brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Links to other resources</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_LinksTwo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:17133">HGNC</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.ensembl.org/id/ENSG00000079263">Ensembl</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.alliancegenome.org/gene/HGNC:17133">AllianceGenome</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=geneid&org=9606&l=11262">AceView</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position=NM_007237">UCSC</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://phgkb.cdc.gov/PHGKB/huGEPedia.action?firstQuery=SP140&geneID=11262&typeOption=gene&which=2&pubOrderType=pubD&typeSubmit=GO&check=y">HuGE Navigator</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.genome.jp/dbget-bin/www_bget?hsa:11262">KEGG</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-general-info">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>General information</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_GeneralInfo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="/pmc/?term=PMC4383897+OR+PMC3013746+OR+PMC1761442+OR+PMC539985">About Gene</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3840">FAQ</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://ftp.ncbi.nlm.nih.gov/gene/">FTP site</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3841/">Help</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3842/">My NCBI help</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK21085/">NCBI Handbook</a>
|
||
</li>
|
||
<li>
|
||
<a href="/gene/statistics/">Statistics</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-related-sites">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related sites</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedSites.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_RelatedSites" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedSites.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/BLAST">BLAST</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/genome">Genome</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/bioproject">BioProject</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/genome/gdv/">Genome Data Viewer</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/geo">GEO</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/omim">OMIM</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/probe">Probe</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/RefSeq">RefSeq</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-feedback">
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<div class="portlet_head">
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<div class="portlet_title">
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<h3>Feedback</h3>
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</div>
|
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<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Feedback.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_Feedback" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Feedback.Shutter"></a>
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</div>
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<a href="https://support.ncbi.nlm.nih.gov/ics/support/ticketnewwizard.asp?style=classic&deptID=28049">Contact Help Desk</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/RefSeq/update.cgi?geneid=11262&symbol=SP140">Submit Correction</a>
|
||
</li>
|
||
<li>
|
||
<a href="/gene/submit-generif?geneId=11262&sym=SP140&name=SP140 nuclear body protein&org=Homo sapiens">Submit GeneRIF</a>
|
||
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|
||
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<li>
|
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<a href="https://www.ncbi.nlm.nih.gov/mailman/listinfo/refseq-announce">RefSeq</a>
|
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</li>
|
||
</ul>
|
||
</div>
|
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</div>
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<!-- <component id="Gene_RVFullReport.Gene_RightColMenuLinks"/>-->
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<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory" cmd="ClearHT" href="?cmd=ClearHT&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory">
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Clear
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<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOn" cmd="HTOff" href="?cmd=HTOff&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle">
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Turn Off
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Turn On
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67d4335367c23b31e0ab0767">SP140 SP140 nuclear body protein [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">SP140 SP140 nuclear body protein [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:11262</div></div>
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<div class="tertiary">Gene</div>
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=2" href="/portal/utils/pageresolver.fcgi?recordid=67d4335284f3725e59316efb">LOC129935752 [Homo sapiens]</a>
|
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<div class="ralinkpop offscreen_noflow">LOC129935752 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:129935752</div></div>
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<div class="tertiary">Gene</div>
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</li>
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<li class="ra_rcd ralinkpopper two_line">
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=3" href="/portal/utils/pageresolver.fcgi?recordid=67d4335084f3725e59316990">LOC129935751 [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">LOC129935751 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:129935751</div></div>
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<div class="tertiary">Gene</div>
|
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</li>
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<li class="ra_rcd ralinkpopper two_line">
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=4" href="/portal/utils/pageresolver.fcgi?recordid=67d4334f2f30673f7befe381">LOC129935750 [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">LOC129935750 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:129935750</div></div>
|
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<div class="tertiary">Gene</div>
|
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</li>
|
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<li class="ra_rcd ralinkpopper two_line">
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=5" href="/portal/utils/pageresolver.fcgi?recordid=67d4334e67c23b31e0aae90f">LOC129935749 [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">LOC129935749 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:129935749</div></div>
|
||
<div class="tertiary">Gene</div>
|
||
</li>
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</ul>
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<p class="HTOn">Your browsing activity is empty.</p>
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<p class="HTOff">Activity recording is turned off.</p>
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<p id="turnOn" class="HTOff">
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<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryOn" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryOn" cmd="HTOn" href="?cmd=HTOn&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryOn">Turn recording back on</a>
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<div class="col-lg-3 col-12">
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<p class="address_footer text-white">National Library of Medicine<br />
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<a href="https://www.google.com/maps/place/8600+Rockville+Pike,+Bethesda,+MD+20894/@38.9959508,-77.101021,17z/data=!3m1!4b1!4m5!3m4!1s0x89b7c95e25765ddb:0x19156f88b27635b8!8m2!3d38.9959508!4d-77.0988323" class="text-white" target="_blank" rel="noopener noreferrer">8600 Rockville Pike<br />
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Bethesda, MD 20894</a></p>
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<div class="col-lg-3 col-12 centered-lg">
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<p><a href="https://www.nlm.nih.gov/web_policies.html" class="text-white">Web Policies</a><br />
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<a href="https://www.nih.gov/institutes-nih/nih-office-director/office-communications-public-liaison/freedom-information-act-office" class="text-white">FOIA</a><br />
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<a href="https://www.hhs.gov/vulnerability-disclosure-policy/index.html" class="text-white" id="vdp">HHS Vulnerability Disclosure</a></p>
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<div class="col-lg-3 col-12 centered-lg">
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<p><a class="supportLink text-white" href="https://support.nlm.nih.gov/">Help</a><br />
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<a href="https://www.nlm.nih.gov/accessibility.html" class="text-white">Accessibility</a><br />
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<a href="https://www.nlm.nih.gov/careers/careers.html" class="text-white">Careers</a></p>
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<nav class="bottom-links">
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<ul class="mt-3">
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<li>
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<a class="text-white" href="//www.nlm.nih.gov/">NLM</a>
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<li>
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<a class="text-white" href="https://www.nih.gov/">NIH</a>
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<a class="text-white" href="https://www.hhs.gov/">HHS</a>
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