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<div class="search"><div class="search_form"><label for="database" class="offscreen_noflow">Search database</label><select id="database"><optgroup label="Recent"><option value="books">Books</option><option value="pubmed">PubMed</option><option value="medgen">MedGen</option><option value="clinvar" class="last">ClinVar</option></optgroup><optgroup label="All"><option value="gquery">All Databases</option><option value="assembly" data-ac_dict="assembly">Assembly</option><option value="biocollections">Biocollections</option><option value="bioproject">BioProject</option><option value="biosample">BioSample</option><option value="books">Books</option><option value="clinvar">ClinVar</option><option value="cdd">Conserved Domains</option><option value="gap">dbGaP</option><option value="dbvar">dbVar</option><option value="gene" selected="selected" data-ac_dict="gene">Gene</option><option value="genome" data-ac_dict="genome">Genome</option><option value="gds">GEO DataSets</option><option value="geoprofiles">GEO Profiles</option><option value="gtr">GTR</option><option value="ipg">Identical Protein Groups</option><option value="medgen">MedGen</option><option value="mesh">MeSH</option><option value="nlmcatalog">NLM Catalog</option><option value="nuccore" data-ac_dict="nuccore">Nucleotide</option><option value="omim">OMIM</option><option value="pmc">PMC</option><option value="protein" data-ac_dict="protein">Protein</option><option value="proteinclusters">Protein Clusters</option><option value="protfam">Protein Family Models</option><option value="pcassay">PubChem BioAssay</option><option value="pccompound">PubChem Compound</option><option value="pcsubstance">PubChem Substance</option><option value="pubmed">PubMed</option><option value="snp">SNP</option><option value="sra">SRA</option><option value="structure">Structure</option><option value="taxonomy">Taxonomy</option><option value="toolkit">ToolKit</option><option value="toolkitall">ToolKitAll</option><option value="toolkitbookgh">ToolKitBookgh</option></optgroup></select><div class="nowrap"><label for="term" class="offscreen_noflow" accesskey="/">Search term</label><div class="nowrap"><input type="text" name="term" id="term" title="Search Gene. Use up and down arrows to choose an item from the autocomplete." value="" class="jig-ncbiclearbutton jig-ncbiautocomplete" data-jigconfig="dictionary:'gene',disableUrl:'NcbiSearchBarAutoComplCtrl'" autocomplete="off" data-sbconfig="ds:'no',pjs:'yes',afs:'yes'" /></div><button id="search" type="submit" class="button_search nowrap" cmd="go">Search</button></div></div><ul class="searchlinks inline_list"><set></set><li><a href="/gene/advanced">Advanced</a></li><li class="help"><a id="help" class="jig-ncbihelpwindow" target="ncbihelp" name="help" href="/books/NBK3841/">Help</a></li></ul></div>
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<div class="facet_cont" data-db="gene" data-default_grps="fg_gene-sources,fg_categories,fg_sequence-content,fg_status" data-sd="db:'gene',op:'select',term:'',qk:'20457',linkname:'',idsfromresult:'10945',extra:''"><ul class="facet" data-filter_id="gene-sources" id="_gene-sources"><li class="filter_grp "><div class="clearfix"><h3>Gene sources</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="genomic">Genomic</a></li></ul></li></ul><ul class="facet" data-filter_id="categories" id="_categories"><li class="filter_grp "><div class="clearfix"><h3>Categories</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="alt-splicing">Alternatively spliced</a></li><li class="fil_val"><a href="#" data-value_id="annotated-genes">Annotated genes</a></li><li class="fil_val"><a href="#" data-value_id="gene-type-protein-coding">Protein-coding</a></li></ul></li></ul><ul class="facet" data-filter_id="sequence-content" id="_sequence-content"><li class="filter_grp "><div class="clearfix"><h3>Sequence content</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="seq-ccds">CCDS</a></li><li class="fil_val"><a href="#" data-value_id="seq-ensembl">Ensembl</a></li><li class="fil_val"><a href="#" data-value_id="refseq">RefSeq</a></li></ul></li></ul><ul class="facet" data-filter_id="status" id="_status"><li class="filter_grp "><div class="clearfix"><h3>Status</h3><a href="#" data-value_id="" class="clear clear_show">Clear</a></div><ul><li class="fil_val selected"><a href="#" data-value_id="current-only">Current</a><span class="fcount">(1)</span></li></ul></li></ul><div id="chr-location-facet-wrapper" data-bid="MCID_67d41907f59ffc79264d8ce3" data-hid="MCID_67d2a666fe1ad803e8633767" data-qky="20457" class="disabled" style="display:none"><ul class="facet" data-filter_id="chromosomal-region" id="_chromosomal-region" data-of="yes"><li class="filter_grp of_grp"><div class="clearfix"><h3>Chromosome locations</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><a id="facet_ofchromosomal-region" href="#facet_of_divchromosomal-region" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'middle left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '375px'" data-value_id="fetch_more">more...</a><div id="facet_of_divchromosomal-region" style="display:none;" class="of_popup"><h4>Chromosome locations</h4><label for="organism-filter" style="width:100%;margin-bottom:.2em;" class="">Select an organism by typing or scrolling</label><input type="text" placeholder="Enter text to narrow down the list" id="organism-filter" style="width:98%;" autocomplete="off" /><br /><div id="chr-region-tax-list"><select id="of_chromosomal-region" size="9" class="chr-region-tax-list" style="width:100%;"></select></div><div id="chr-location-info-ctrl" data-disabled="disabled"><div class="chr-field"><label for="chr-name">Chromosome</label><br /><select id="chr-name" class="chr-field" disabled="disabled"></select></div><div class="chr-field"><label for="chr-from">From</label><br /><input type="text" name="chr-from" id="chr-from" disabled="disabled" class="chr-field" /></div><div class="chr-field"><label for="chr-to">To</label><br /><input type="text" name="chr-to" id="chr-to" disabled="disabled" class="chr-field" /></div></div><div class="actions clearfix"><button class="jig-ncbibutton of_add apply-chr" data-jigconfig="'color': 'ui-ncbibutton-blue'">Apply</button></div></div></ul></li></ul></div><ul class="facet facet_reset"><li><a href="#" data-value_id="reset">Clear all</a></li></ul><ul class="facet_tools"><li><a id="more_filter_groups_link" href="#more_filter_groups" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'top left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '180px'">
Show additional filters</a></li><div id="more_filter_groups" style="display:none;" class="facets_dialog"><button class="ui-ncbipopper-close-button ui-ncbipopper-close-button-generated ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-blue" generated="true" role="button" aria-disabled="false"><span class="ui-button-text">x</span></button><h4>Additional filters</h4><ul class="filter_groups_more facet"><li><input type="checkbox" id="fg_gene-sources" /><label for="fg_gene-sources">Gene sources</label></li><li><input type="checkbox" id="fg_categories" /><label for="fg_categories">Categories</label></li><li><input type="checkbox" id="fg_sequence-content" /><label for="fg_sequence-content">Sequence content</label></li><li><input type="checkbox" id="fg_status" /><label for="fg_status">Status</label></li><li><input type="checkbox" id="fg_chromosomal-region" /><label for="fg_chromosomal-region">Chromosome locations</label></li><li><input id="fg_field_search" type="checkbox" /><label for="fg_field_search">Search fields</label></li></ul><div class="actions clearfix"><button class="filter_groups_more_apply jig-ncbibutton primary-action" id="filter_groups_apply" data-jigconfig="'color': 'ui-ncbibutton-blue'">Show</button></div></div></ul><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetsUrlFrag" sid="1" type="hidden" value="filters=current-only" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetSubmitted" sid="1" type="hidden" value="false" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.BMFacets" sid="1" type="hidden" value="" /></div>
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<h1 class="title" id="gene-name"><span class="gn" style="padding-right:.5em;">KDELR1</span> KDEL endoplasmic reticulum protein retention receptor 1 [ <em class="tax">Homo sapiens</em> (human)
]
</h1>
<span class="geneid">Gene ID: 10945, updated on
8-Mar-2025</span>
</div>
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<div class="rprt-section gene-summary">
<section class="rprt-section-header" id="summary">
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<div id="summaryDiv" class="section">
<dl id="summaryDl">
<dt class="noline"> Official
Symbol</dt>
<dd class="noline">KDELR1<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
<dt> Official
Full Name</dt>
<dd>KDEL endoplasmic reticulum protein retention receptor 1<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
<dt>Primary source</dt>
<dd>
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6304" data-gblink-text="Ensembl">HGNC:HGNC:6304</a>
</dd>
<dt>See related</dt>
<dd>
<a href="http://www.ensembl.org/id/ENSG00000105438" data-gblink-text="Ensembl" class="genome-browser-link" data-genome-browser-link-sort="5" data-gb-url="http://www.ensembl.org/loc/ENSG00000105438">Ensembl:ENSG00000105438</a>
<a href="https://www.ncbi.nlm.nih.gov/omim/131235" data-gblink-text="Ensembl" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=131235">MIM:131235;</a>
<a href="https://www.alliancegenome.org/gene/HGNC:6304" data-gblink-text="Ensembl" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=HGNC:6304">AllianceGenome:HGNC:6304</a>
</dd>
<dt>Gene type</dt>
<dd>protein coding</dd>
<dt>RefSeq status</dt>
<dd>REVIEWED</dd>
<dt>Organism</dt>
<dd class="tax">
<a href="/Taxonomy/Browser/wwwtax.cgi?id=9606" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=9606">Homo sapiens</a>
</dd>
<dt>Lineage</dt>
<dd class="tax">Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo</dd>
<dt>Also known as</dt>
<dd>ERD2; HDEL; PM23; ERD2.1</dd>
<dt>Summary</dt>
<dd>Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product. [provided by RefSeq, Jul 2008]</dd>
<dt>Expression</dt>
<dd>Ubiquitous expression in ovary (RPKM 78.6), thyroid (RPKM 73.5) and 25 other tissues <a href="#gene-expression">See more</a></dd>
<dt>Orthologs</dt>
<dd class="ortholog-links">
<a href="https://www.ncbi.nlm.nih.gov/gene/68137">mouse</a>
<a href="/gene/10945/ortholog/">all</a>
</dd>
<dt style="padding-top:.5em;">
<span class="new-icon">NEW</span>
</dt>
<dd style="padding-top:.5em;">
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/10945/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="gene_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Gene table</a></strong>
<br />
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/10945/products/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="transcript_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Transcript table</a></strong>
</dd>
</dl>
</div>
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<div class="rprt-section gene-genomic-context">
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<span class="ui-ncbitoggler-master-text">Genomic context</span>
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</h2>
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</section>
<div class="rprt-section-body">
<div class="gc_cont">
<div class="gt_cont_contents">
<div style="float:right"><span>See KDELR1 in </span><a href="/genome/gdv/?context=gene&amp;acc=10945" class="link-to-gdv genome-browser-link" data-genome-browser-link-sort="1" data-acc="GCF_000001405.40">Genome Data Viewer</a> </div>
<dl class="dl-chr-info" style="float:left;margin-top:0;">
<dt>Location: </dt>
<dd>
<span style="display:inline-block;">19q13.33</span>
</dd>
</dl>
</div>
<dl class="dl-chr-info exon-count">
<dt>Exon count: </dt>
<dd>7</dd>
</dl>
<div class="ui-ncbigrid-outer-div" id="genomic-context-tbl-location">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-jigconfig="">
<thead>
<tr>
<th style="max-width:15%">Annotation release</th>
<th style="max-width:10%">Status</th>
<th>Assembly</th>
<th>
<span title="Chromosome">Chr</span>
</th>
<th>Location</th>
</tr>
</thead>
<tbody>
<tr>
<td>RS_2024_08</td>
<td>current</td>
<td>GRCh38.p14 (<a href="/assembly/GCF_000001405.40/" ref="ncbi_uid=10945&amp;link_uid=GCF_000001405.40">GCF_000001405.40</a>)</td>
<td>19</td>
<td>NC_000019.10 (48382575..48397412, complement) </td>
</tr>
<tr>
<td>RS_2024_08</td>
<td>current</td>
<td>T2T-CHM13v2.0 (<a href="/assembly/GCF_009914755.1/" ref="ncbi_uid=10945&amp;link_uid=GCF_009914755.1">GCF_009914755.1</a>)</td>
<td>19</td>
<td>NC_060943.1 (51376721..51392513, complement) </td>
</tr>
<tr>
<td>RS_2024_09</td>
<td>previous assembly</td>
<td>GRCh37.p13 (<a href="/assembly/GCF_000001405.25/" ref="ncbi_uid=10945&amp;link_uid=GCF_000001405.25">GCF_000001405.25</a>)</td>
<td>19</td>
<td>NC_000019.9 (48885832..48894808, complement) </td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
<p class="withnote margin_t2em"><strong>Chromosome 19 - NC_000019.10</strong><img usemap="#nbrMap10945_568815579" border="0" alt="Genomic Context describing neighboring genes" src="/gutils/geneneighb.fcgi?geneid=10945&amp;nuc_gi=568815579&amp;n0=TMEM143&amp;n1=LOC127891903&amp;n2=LOC127891904&amp;n3=LOC127891905&amp;n4=LOC127891906&amp;n5=LOC130064850&amp;n6=LOC130064851&amp;n7=SYNGR4&amp;n8=LOC130064852&amp;n9=LOC127891907&amp;n10=LOC127891908&amp;n11=KDELR1&amp;n12=LOC130064853&amp;n13=LOC130064854&amp;n14=GRIN2D&amp;n15=LOC129664489&amp;n16=LOC130064855&amp;n17=LOC130064856&amp;n18=LOC127891909&amp;n19=LOC112552169&amp;n20=LOC127891910&amp;n21=LOC127891911&amp;n22=LOC130064857&amp;n23=LOC112552170&amp;n24=LOC127891912&amp;n25=LOC130064858&amp;n26=LOC130064859&amp;n27=GRWD1&amp;n28=KCNJ14&amp;n29=LOC127891913&amp;n30=LOC105372430&amp;n31=LOC127891914&amp;n32=LOC127891915&amp;n33=CYTH2" /><map name="nbrMap10945_568815579" id="nbrMap10945_568815579">
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr19:48836515-48837250')" onMouseOut="hidetip()" coords="4,23,74,31" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:48836515-48837250" href="/gene/127891903" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr19:48842328-48843265')" onMouseOut="hidetip()" coords="18,35,88,43" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:48842328-48843265" href="/gene/127891904" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr19:48845414-48845914')" onMouseOut="hidetip()" coords="25,47,95,55" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:48845414-48845914" href="/gene/127891905" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr19:48845915-48846415')" onMouseOut="hidetip()" coords="27,59,97,67" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:48845915-48846415" href="/gene/127891906" />
<area shape="rect" onMouseOver="showtip(this,event,'transmembrane protein 143')" onMouseOut="hidetip()" coords="27,71,140,79" alt="Neighboring gene transmembrane protein 143" href="/gene/55260" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 14888')" onMouseOut="hidetip()" coords="77,23,147,31" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14888" href="/gene/130064850" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 14889')" onMouseOut="hidetip()" coords="78,83,148,91" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14889" href="/gene/130064851" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 14890')" onMouseOut="hidetip()" coords="79,95,149,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14890" href="/gene/130064852" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr19:48876382-48876882')" onMouseOut="hidetip()" coords="100,35,170,43" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:48876382-48876882" href="/gene/127891907" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr19:48876883-48877383')" onMouseOut="hidetip()" coords="101,47,171,55" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:48876883-48877383" href="/gene/127891908" />
<area shape="rect" onMouseOver="showtip(this,event,'synaptogyrin 4')" onMouseOut="hidetip()" coords="108,59,169,67" alt="Neighboring gene synaptogyrin 4" href="/gene/23546" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 14891')" onMouseOut="hidetip()" coords="141,71,211,79" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14891" href="/gene/130064853" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 10878')" onMouseOut="hidetip()" coords="143,107,213,115" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10878" href="/gene/130064854" />
<area shape="rect" onMouseOver="showtip(this,event,'ReSE screen-validated silencer GRCh37_chr19:48899313-48899496')" onMouseOut="hidetip()" coords="154,83,224,91" alt="Neighboring gene ReSE screen-validated silencer GRCh37_chr19:48899313-48899496" href="/gene/129664489" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 10879')" onMouseOut="hidetip()" coords="160,95,230,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10879" href="/gene/130064855" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 10880')" onMouseOut="hidetip()" coords="161,119,231,127" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10880" href="/gene/130064856" />
<area shape="rect" onMouseOver="showtip(this,event,'OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:48903941-48904482')" onMouseOut="hidetip()" coords="166,131,236,139" alt="Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:48903941-48904482" href="/gene/127891909" />
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 12315')" onMouseOut="hidetip()" coords="173,35,243,43" alt="Neighboring gene Sharpr-MPRA regulatory region 12315" href="/gene/112552169" />
<area shape="rect" onMouseOver="showtip(this,event,'glutamate ionotropic receptor NMDA type subunit 2D')" onMouseOut="hidetip()" coords="179,47,334,55" alt="Neighboring gene glutamate ionotropic receptor NMDA type subunit 2D" href="/gene/2906" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:48917645-48918366')" onMouseOut="hidetip()" coords="198,59,268,67" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:48917645-48918366" href="/gene/127891910" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr19:48921924-48922690')" onMouseOut="hidetip()" coords="209,143,279,151" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:48921924-48922690" href="/gene/127891911" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 14894')" onMouseOut="hidetip()" coords="211,155,281,163" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14894" href="/gene/130064857" />
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 8588')" onMouseOut="hidetip()" coords="223,23,293,31" alt="Neighboring gene Sharpr-MPRA regulatory region 8588" href="/gene/112552170" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr19:48947127-48947818')" onMouseOut="hidetip()" coords="269,35,339,43" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:48947127-48947818" href="/gene/127891912" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 14895')" onMouseOut="hidetip()" coords="273,59,343,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14895" href="/gene/130064858" />
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 14896')" onMouseOut="hidetip()" coords="274,71,344,79" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14896" href="/gene/130064859" />
<area shape="rect" onMouseOver="showtip(this,event,'glutamate rich WD repeat containing 1')" onMouseOut="hidetip()" coords="309,23,362,31" alt="Neighboring gene glutamate rich WD repeat containing 1" href="/gene/83743" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:48964846-48965804')" onMouseOut="hidetip()" coords="311,83,381,91" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:48964846-48965804" href="/gene/127891913" />
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC105372430')" onMouseOut="hidetip()" coords="321,95,392,103" alt="Neighboring gene uncharacterized LOC105372430" href="/gene/105372430" />
<area shape="rect" onMouseOver="showtip(this,event,'potassium inwardly rectifying channel subfamily J member 14')" onMouseOut="hidetip()" coords="327,107,386,115" alt="Neighboring gene potassium inwardly rectifying channel subfamily J member 14" href="/gene/3770" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr19:48971727-48972227')" onMouseOut="hidetip()" coords="328,119,398,127" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:48971727-48972227" href="/gene/127891914" />
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:48972285-48973278')" onMouseOut="hidetip()" coords="329,131,399,139" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:48972285-48973278" href="/gene/127891915" />
<area shape="rect" onMouseOver="showtip(this,event,'cytohesin 2')" onMouseOut="hidetip()" coords="365,23,423,31" alt="Neighboring gene cytohesin 2" href="/gene/9266" />
</map>
</p>
</div>
</div>
<div class="rprt-section gene-genomic-regions-transcripts-products">
<section class="rprt-section-header" id="genomic-regions-transcripts-products">
<h2 id="header-genomic-regions-transcripts-products">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-regions-transcripts-products .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Genomic regions, transcripts, and products</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Genomic_Regions_Transcripts_a" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div>
<div style="text-align:right;">Go to <a href="#reference-sequences">reference sequence details</a></div>
</div>
<div>
<p class="choose">
<label for="accession" class="label">Genomic Sequence: </label>
<select name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.accessionList" sid="1" id="accessionList" data-taxid="9606" data-geneid="10945">
<option value="NC_000019.10_48382574_48397411">NC_000019.10 Chromosome 19 Reference GRCh38.p14 Primary Assembly</option>
<option value="NC_060943.1_51376720_51392512">NC_060943.1 Chromosome 19 Alternate T2T-CHM13v2.0</option>
<option value="NC_000019.9_48885831_48894807">NC_000019.9 Chromosome 19 Reference GRCh37.p13 Primary Assembly</option>
</select>
</p>
</div>
<div id="NC_000019" class="divAccession">
<div class="seq-viewer">
<p class="note-link">
<strong>Go to nucleotide:</strong>
<a title="Nucleotide Graphic report" href="/nuccore/NC_000019.10?report=graph&amp;from=48380348&amp;to=48399637&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=NC_000019.10">Graphics</a>
<a title="Nucleotide FASTA report" href="/nuccore/NC_000019.10?report=fasta&amp;from=48382575&amp;to=48397412&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=NC_000019.10">FASTA</a>
<a title="Nucleotide GenBank report" href="/nuccore/NC_000019.10?report=genbank&amp;from=48382575&amp;to=48397412&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=NC_000019.10">GenBank</a>
</p>
<div id="divNC_000019" class="SeqViewerApp" style="clear:both;" data-sv="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000019.10&amp;from=48380348&amp;to=48399637&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.40">
<a href="?appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000019.10&amp;from=48380348&amp;to=48399637&amp;strand=true&amp;app_context=Gene&amp;assm_context=GCF_000001405.40"></a>
</div>
</div>
</div>
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000019.10" sid="1" type="hidden" id="nucleotideLink_NC_000019_10_48382574_48397411" value="&lt;p class=&quot;note-link&quot;&gt;&lt;strong&gt;Go to nucleotide:&lt;/strong&gt;&lt;a title=&quot;Nucleotide Graphic report&quot; href=&quot;/nuccore/NC_000019.10?report=graph&amp;amp;from=48380348&amp;amp;to=48399637&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.40&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=10945&amp;amp;link_uid=NC_000019.10&quot;&gt;Graphics&lt;/a&gt;&lt;a title=&quot;Nucleotide FASTA report&quot; href=&quot;/nuccore/NC_000019.10?report=fasta&amp;amp;from=48382575&amp;amp;to=48397412&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=10945&amp;amp;link_uid=NC_000019.10&quot;&gt;FASTA&lt;/a&gt;&lt;a title=&quot;Nucleotide GenBank report&quot; href=&quot;/nuccore/NC_000019.10?report=genbank&amp;amp;from=48382575&amp;amp;to=48397412&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=10945&amp;amp;link_uid=NC_000019.10&quot;&gt;GenBank&lt;/a&gt;&lt;/p&gt;" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000019.10" sid="1" type="hidden" id="relString_NC_000019_10_48382574_48397411" value="appname=ncbigene&amp;amp;embedded=true&amp;amp;noslider=1&amp;amp;id=NC_000019.10&amp;amp;from=48380348&amp;amp;to=48399637&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.40" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_060943.1" sid="1" type="hidden" id="nucleotideLink_NC_060943_1_51376720_51392512" value="&lt;p class=&quot;note-link&quot;&gt;&lt;strong&gt;Go to nucleotide:&lt;/strong&gt;&lt;a title=&quot;Nucleotide Graphic report&quot; href=&quot;/nuccore/NC_060943.1?report=graph&amp;amp;from=51374351&amp;amp;to=51394881&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_009914755.1&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=10945&amp;amp;link_uid=NC_060943.1&quot;&gt;Graphics&lt;/a&gt;&lt;a title=&quot;Nucleotide FASTA report&quot; href=&quot;/nuccore/NC_060943.1?report=fasta&amp;amp;from=51376721&amp;amp;to=51392513&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=10945&amp;amp;link_uid=NC_060943.1&quot;&gt;FASTA&lt;/a&gt;&lt;a title=&quot;Nucleotide GenBank report&quot; href=&quot;/nuccore/NC_060943.1?report=genbank&amp;amp;from=51376721&amp;amp;to=51392513&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=10945&amp;amp;link_uid=NC_060943.1&quot;&gt;GenBank&lt;/a&gt;&lt;/p&gt;" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_060943.1" sid="1" type="hidden" id="relString_NC_060943_1_51376720_51392512" value="appname=ncbigene&amp;amp;embedded=true&amp;amp;noslider=1&amp;amp;id=NC_060943.1&amp;amp;from=51374351&amp;amp;to=51394881&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_009914755.1" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000019.9" sid="1" type="hidden" id="nucleotideLink_NC_000019_9_48885831_48894807" value="&lt;p class=&quot;note-link&quot;&gt;&lt;strong&gt;Go to nucleotide:&lt;/strong&gt;&lt;a title=&quot;Nucleotide Graphic report&quot; href=&quot;/nuccore/NC_000019.9?report=graph&amp;amp;from=48884485&amp;amp;to=48896153&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.25&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=10945&amp;amp;link_uid=NC_000019.9&quot;&gt;Graphics&lt;/a&gt;&lt;a title=&quot;Nucleotide FASTA report&quot; href=&quot;/nuccore/NC_000019.9?report=fasta&amp;amp;from=48885832&amp;amp;to=48894808&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=10945&amp;amp;link_uid=NC_000019.9&quot;&gt;FASTA&lt;/a&gt;&lt;a title=&quot;Nucleotide GenBank report&quot; href=&quot;/nuccore/NC_000019.9?report=genbank&amp;amp;from=48885832&amp;amp;to=48894808&amp;amp;strand=true&quot; ref=&quot;ordinalpos=1&amp;amp;ncbi_uid=10945&amp;amp;link_uid=NC_000019.9&quot;&gt;GenBank&lt;/a&gt;&lt;/p&gt;" />
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000019.9" sid="1" type="hidden" id="relString_NC_000019_9_48885831_48894807" value="appname=ncbigene&amp;amp;embedded=true&amp;amp;noslider=1&amp;amp;id=NC_000019.9&amp;amp;from=48884485&amp;amp;to=48896153&amp;amp;strand=true&amp;amp;app_context=Gene&amp;amp;assm_context=GCF_000001405.25" />
</div>
</div>
<div class="rprt-section gene-gene-expression">
<section class="rprt-section-header" id="gene-expression">
<h2 id="header-gene-expression">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-gene-expression .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Expression</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Expression" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div>
<div style="text-align:right;">
<a href="/gene/10945/?report=expression" data-url="/gene/10945/?report=expression" id="gene-expression-see-details">See details</a>
</div>
<div id="gene-expression-app" data-url="https://www.ncbi.nlm.nih.gov/gene/10945" data-report-type="summary">
<div>
<script type="text/javascript">
window.tissues_data = {'adrenal 10wk': {'id': '10945_Adrenal_10wk_PRJNA270632', 'gene': 10945, 'source_name': 'adrenal 10wk', 'full_rpkm': 10.5384, 'exp_rpkm': 10.5, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416308371483}, 'adrenal 16wk': {'id': '10945_Adrenal_16wk_PRJNA270632', 'gene': 10945, 'source_name': 'adrenal 16wk', 'full_rpkm': 14.1784, 'exp_rpkm': 14.2, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416308371484}, 'adrenal 18wk': {'id': '10945_Adrenal_18wk_PRJNA270632', 'gene': 10945, 'source_name': 'adrenal 18wk', 'full_rpkm': 16.0398, 'exp_rpkm': 16.0, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416308371485}, 'adrenal 20wk': {'id': '10945_Adrenal_20wk_PRJNA270632', 'gene': 10945, 'source_name': 'adrenal 20wk', 'full_rpkm': 14.4436, 'exp_rpkm': 14.4, 'var': 2.82852, 'project_desc': 'PRJNA270632', '_version_': 1785734416308371486}, 'heart 10wk': {'id': '10945_Heart_10wk;_PRJNA270632', 'gene': 10945, 'source_name': 'heart 10wk', 'full_rpkm': 13.1429, 'exp_rpkm': 13.1, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416308371487}, 'heart 11wk': {'id': '10945_Heart_11wk;_PRJNA270632', 'gene': 10945, 'source_name': 'heart 11wk', 'full_rpkm': 10.5496, 'exp_rpkm': 10.5, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416308371488}, 'heart 17wk': {'id': '10945_Heart_17wk;_PRJNA270632', 'gene': 10945, 'source_name': 'heart 17wk', 'full_rpkm': 9.84201, 'exp_rpkm': 9.84, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416308371489}, 'heart 18wk': {'id': '10945_Heart_18wk;_PRJNA270632', 'gene': 10945, 'source_name': 'heart 18wk', 'full_rpkm': 8.6089, 'exp_rpkm': 8.61, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416308371490}, 'heart 20wk': {'id': '10945_Heart_20wk_PRJNA270632', 'gene': 10945, 'source_name': 'heart 20wk', 'full_rpkm': 5.38727, 'exp_rpkm': 5.39, 'var': 7.23906, 'project_desc': 'PRJNA270632', '_version_': 1785734416308371491}, 'intestine 10wk': {'id': '10945_Intestine_10wk_PRJNA270632', 'gene': 10945, 'source_name': 'intestine 10wk', 'full_rpkm': 5.58241, 'exp_rpkm': 5.58, 'var': 1.253678, 'project_desc': 'PRJNA270632', '_version_': 1785734416308371492}, 'intestine 11wk': {'id': '10945_Intestine_11wk_PRJNA270632', 'gene': 10945, 'source_name': 'intestine 11wk', 'full_rpkm': 9.4513, 'exp_rpkm': 9.45, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416308371493}, 'intestine 15wk': {'id': '10945_Intestine_15wk_PRJNA270632', 'gene': 10945, 'source_name': 'intestine 15wk', 'full_rpkm': 11.9639, 'exp_rpkm': 12.0, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416308371494}, 'intestine 17wk': {'id': '10945_Intestine_17wk_PRJNA270632', 'gene': 10945, 'source_name': 'intestine 17wk', 'full_rpkm': 8.87981, 'exp_rpkm': 8.88, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416308371495}, 'intestine 20wk': {'id': '10945_Intestine_20wk_PRJNA270632', 'gene': 10945, 'source_name': 'intestine 20wk', 'full_rpkm': 21.4961, 'exp_rpkm': 21.5, 'var': 16.94522, 'project_desc': 'PRJNA270632', '_version_': 1785734416308371496}, 'kidney 10wk': {'id': '10945_Kidney_10wk_PRJNA270632', 'gene': 10945, 'source_name': 'kidney 10wk', 'full_rpkm': 10.788, 'exp_rpkm': 10.8, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416308371497}, 'kidney 16wk': {'id': '10945_Kidney_16wk_PRJNA270632', 'gene': 10945, 'source_name': 'kidney 16wk', 'full_rpkm': 6.45744, 'exp_rpkm': 6.46, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416308371498}, 'kidney 20wk': {'id': '10945_Kidney_20wk_PRJNA270632', 'gene': 10945, 'source_name': 'kidney 20wk', 'full_rpkm': 4.07734, 'exp_rpkm': 4.08, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416308371499}, 'lung 10wk': {'id': '10945_Lung_10wk_PRJNA270632', 'gene': 10945, 'source_name': 'lung 10wk', 'full_rpkm': 12.4763, 'exp_rpkm': 12.5, 'var': 1.443104, 'project_desc': 'PRJNA270632', '_version_': 1785734416309420032}, 'lung 17wk': {'id': '10945_Lung_17wk_PRJNA270632', 'gene': 10945, 'source_name': 'lung 17wk', 'full_rpkm': 11.9108, 'exp_rpkm': 11.9, 'var': 2.98724, 'project_desc': 'PRJNA270632', '_version_': 1785734416309420033}, 'lung 20wk': {'id': '10945_Lung_20wk_PRJNA270632', 'gene': 10945, 'source_name': 'lung 20wk', 'full_rpkm': 10.8866, 'exp_rpkm': 10.9, 'var': 8.56604, 'project_desc': 'PRJNA270632', '_version_': 1785734416309420034}, 'stomach 10wk': {'id': '10945_Stomach_10wk_PRJNA270632', 'gene': 10945, 'source_name': 'stomach 10wk', 'full_rpkm': 11.235, 'exp_rpkm': 11.2, 'var': 2.46658, 'project_desc': 'PRJNA270632', '_version_': 1785734416309420035}, 'stomach 16wk': {'id': '10945_Stomach_16wk_PRJNA270632', 'gene': 10945, 'source_name': 'stomach 16wk', 'full_rpkm': 15.6949, 'exp_rpkm': 15.7, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416309420036}, 'stomach 18wk': {'id': '10945_Stomach_18wk_PRJNA270632', 'gene': 10945, 'source_name': 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<div>
<select name="p" id="project-selector">
<option value="SRP051249" selected="selected" data-bioproject="PRJNA270632">
Tissue-specific circular RNA induction during human fetal development
</option>
<option value="SRP056969" data-bioproject="PRJNA280600">
RNA sequencing of total RNA from 20 human tissues
</option>
<option value="ERP003613" data-bioproject="PRJEB4337">
HPA RNA-seq normal tissues
</option>
</select>
<ul id="project-summary">
<li id="project-summary-title">Project title:
Tissue-specific circular RNA induction during human fetal development
</li>
<li id="project-summary-desc">Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA</li>
<li id="project-summary-bioprojects">BioProject: <a href="/bioproject/PRJNA270632/">PRJNA270632</a>
</li>
<li id="project-summary-pubs">Publication:
<span><a href="/pubmed/26076956/">PMID 26076956</a></span>
</li>
<li id="project-summary-analysis-date">Analysis date: Mon Apr 2 22:54:59 2018</li>
</ul>
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<a href="#" class="jig-ncbitoggler-open">Related articles in PubMed</a>
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<li>
<a href="/pubmed/1310258/" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=1310258">Ligand-induced redistribution of a human KDEL receptor from the Golgi complex to the endoplasmic reticulum.</a>
<span class="pubmed-auth-date"> Lewis MJ, <em>et al</em>. Cell, 1992 Jan 24. PMID 1310258</span>
</li>
<li>
<a href="/pubmed/25117681/" ref="ordinalpos=2&amp;ncbi_uid=10945&amp;link_uid=25117681">Control systems of membrane transport at the interface between the endoplasmic reticulum and the Golgi.</a>
<span class="pubmed-auth-date"> Cancino J, <em>et al</em>. Dev Cell, 2014 Aug 11. PMID 25117681</span>
</li>
<li>
<a href="/pubmed/23873287/" ref="ordinalpos=3&amp;ncbi_uid=10945&amp;link_uid=23873287">Regulation of Golgi signaling and trafficking by the KDEL receptor.</a>
<span class="pubmed-auth-date"> Cancino J, <em>et al</em>. Histochem Cell Biol, 2013 Oct. PMID 23873287</span>
</li>
<li>
<a href="/pubmed/26861384/" ref="ordinalpos=4&amp;ncbi_uid=10945&amp;link_uid=26861384">A KDEL Retrieval System for ER-Golgi Transport of Japanese Encephalitis Viral Particles.</a>
<span class="pubmed-auth-date"> Wang RY, <em>et al</em>. Viruses, 2016 Feb 5. PMID 26861384, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC4776199/" ref="ordinalpos=0&amp;ncbi_uid=10945&amp;link_uid=PMC4776199">Free PMC Article</a></span></span>
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<a href="/pubmed/21684323/" ref="ordinalpos=5&amp;ncbi_uid=10945&amp;link_uid=21684323">The KDEL receptor induces autophagy to promote the clearance of neurodegenerative disease-related proteins.</a>
<span class="pubmed-auth-date"> Wang P, <em>et al</em>. Neuroscience, 2011 Sep 8. PMID 21684323</span>
</li>
</ol>
<p class="see-all-pm">
<a href="/pubmed?LinkName=gene_pubmed&amp;from_uid=10945" title="See all 64 citations in Pubmed">See all (64) citations in PubMed</a>
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<div class="generif-pubmed generif">
<h3 id="generifsgenereferencesintofunctions">
<a href="#" class="jig-ncbitoggler-open">GeneRIFs: Gene References Into Functions</a>
</h3>
<div>
<a href="/gene/about-generif" class="whatisthis">What's a GeneRIF?</a>
<div class="generefbl-link">
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<li class="gene-rif-popper">
<a href="/pubmed/32562023" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=32562023">KDEL receptor is a cell surface receptor that cycles between the plasma membrane and the Golgi via clathrin-mediated transport carriers.</a>
<div id="gene-popper1" class="gene-rif-popper">Title: KDEL receptor is a cell surface receptor that cycles between the plasma membrane and the Golgi via clathrin-mediated transport carriers.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/31337861" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=31337861">Transcriptomics of a KDELR1 knockout cell line reveals modulated cell adhesion properties.</a>
<div id="gene-popper2" class="gene-rif-popper">Title: Transcriptomics of a KDELR1 knockout cell line reveals modulated cell adhesion properties.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/32645101" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=32645101">Cell-type-specific differences in KDEL receptor clustering in mammalian cells.</a>
<div id="gene-popper3" class="gene-rif-popper">Title: Cell-type-specific differences in KDEL receptor clustering in mammalian cells.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/30958660" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=30958660">The cell surface trafficking of PDIA1, PDIA3, and PDIA6 is dependent on KDELR1, which travels in a dynamic manner to the cell surface. This transport is assumed to result in PDI cell surface association, which differs from PDI inducible secretion into the extracellular space.</a>
<div id="gene-popper4" class="gene-rif-popper">Title: KDEL Receptor 1 Contributes to Cell Surface Association of Protein Disulfide Isomerases.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/30760704" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=30760704">Data show that Golgi-based, KDEL receptor-dependent signalling promotes lysosome repositioning to the perinuclear area, involving a complex process intertwined to autophagy, lipid-droplet turnover and Golgi-mediated secretion.</a>
<div id="gene-popper5" class="gene-rif-popper">Title: KDEL receptor regulates secretion by lysosome relocation- and autophagy-dependent modulation of lipid-droplet turnover.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/26861384" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=26861384">KDELR protein mediated the intracellular trafficking of Japanese encephalitis virus particles.</a>
<div id="gene-popper6" class="gene-rif-popper">Title: A KDEL Retrieval System for ER-Golgi Transport of Japanese Encephalitis Viral Particles.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/25682866" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=25682866">A Golgi-based KDELR-dependent signalling pathway controls invadopodia-dependent extracellular matrix degradation.</a>
<div id="gene-popper7" class="gene-rif-popper">Title: A Golgi-based KDELR-dependent signalling pathway controls extracellular matrix degradation.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/26064897" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=26064897">We propose a model whereby in analogy to previous findings (e.g., the RAS-RAF signalling pathway), PHB can act as a signalling scaffold protein to assist in KDELR-dependent Src activation</a>
<div id="gene-popper8" class="gene-rif-popper">Title: Prohibitin: A Novel Molecular Player in KDEL Receptor Signalling.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/23873287" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=23873287">It discuss the particular role of KDEL receptor signaling in the regulation of important pathways involved in the maintenance of the homeostasis of the transport apparatus, and in particular, of the Golgi complex.</a>
<div id="gene-popper9" class="gene-rif-popper">Title: Regulation of Golgi signaling and trafficking by the KDEL receptor.</div>
</li>
<li class="gene-rif-popper">
<a href="/pubmed/25117681" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=25117681">KDEL receptor activates CREB1 and other transcription factors that upregulate transport-related genes</a>
<div id="gene-popper10" class="gene-rif-popper">Title: Control systems of membrane transport at the interface between the endoplasmic reticulum and the Golgi.</div>
</li>
</ol>
</div>
<div class="submit-genrif">
<span>Submit:</span>
<a href="/gene/submit-generif/?geneId=10945&amp;sym=KDELR1&amp;name=KDEL endoplasmic reticulum protein retention receptor 1&amp;org=Homo sapiens">New GeneRIF</a>
<a href="/RefSeq/update.cgi?geneid=10945&amp;symbol=KDELR1;task=fixpub">Correction</a>
<a href="https://www.ncbi.nlm.nih.gov/gene?db=gene&amp;report=generif&amp;term=10945" class="seeall-generif">See all GeneRIFs (15)</a>
</div>
</div>
</div>
</div>
</div>
<div class="rprt-section gene-phenotypes">
<section class="rprt-section-header" id="phenotypes">
<h2 id="header-phenotypes">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-phenotypes .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Phenotypes</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Phenotype" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body info-phenotype">
<p class="nochild-link">
<a href="/gtr/tests/?term=KDELR1[gene]">Find tests for this gene in the NIH Genetic Testing Registry (GTR)</a>
</p>
<p class="nochild-link">
<a href="/gap/PheGenI?tab=1&amp;gene=10945">Review eQTL and phenotype association data in this region using PheGenI</a>
</p>
</div>
</div>
<div class="rprt-section gene-variation">
<section class="rprt-section-header" id="variation">
<h2 id="header-variation">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-variation .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Variation</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.variation" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<p class="nochild-link">
<a href="/clinvar/?term=KDELR1[gene]" ref="log$=recordlinks">See variants in ClinVar</a>
</p>
<p class="nochild-link">
<a href="/dbvar?LinkName=gene_dbvar&amp;from_uid=10945" ref="log$=recordlinks">See studies and variants in dbVar</a>
</p>
<p class="nochild-link">
<a href="/variation/view/?q=10945[geneid]&amp;assm=GCF_000001405.25" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh37.p13)">See Variation Viewer (GRCh37.p13)</a>
</p>
<p class="nochild-link">
<a href="/variation/view/?q=10945[geneid]" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh38)">See Variation Viewer (GRCh38)</a>
</p>
<set></set>
<set></set>
</div>
</div>
<div class="rprt-section gene-pathways">
<section class="rprt-section-header" id="pathways">
<h2 id="header-pathways">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-pathways .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Pathways from PubChem</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<ul class="geneinfo-subsec infopathway">
<iframe title="Pathways in which the gene target is involved" class="pubchem-widget" scrolling="no" src="https://pubchem.ncbi.nlm.nih.gov/gene/10945#section=Pathways&amp;embed=true&amp;hide_all_headings=true&amp;page_size=25" style="border: 0; width: 100%;"></iframe>
<script type="text/javascript" src="https://pubchem.ncbi.nlm.nih.gov/pcfe/libs/iframeResizer.min.js"></script>
<script type="text/javascript">iFrameResize({log: false, checkOrigin: false}, '.pubchem-widget')</script>
</ul>
</div>
</div>
<div class="rprt-section gene-interactions">
<section class="rprt-section-header" id="interactions">
<h2 id="header-interactions">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-interactions .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Interactions</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Interactions" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<table summary="Gene Interaction" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/10945/data/interaction/',webserviceParams: 'p$l=Ajax&amp;p$debugoutput=off', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
<thead>
<tr>
<th id="inter-prod">Products</th>
<th id="inter-interactant">Interactant</th>
<th id="inter-otherGene">Other Gene</th>
<th id="inter-compl">Complex</th>
<th id="inter-source">Source</th>
<th id="inter-pubs">Pubs</th>
<th id="inter-desc">Description</th>
</tr>
</thead>
<tbody></tbody>
</table>
</div>
</div>
<div class="rprt-section gene-general-gene-info">
<section class="rprt-section-header" id="general-gene-info">
<h2 id="header-general-gene-info">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-gene-info .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">General gene information</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.General_Gene_Information" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body" style="">
<div id="gene-markers">
<h3 id="markers">
<a class="jig-ncbitoggler">Markers</a>
</h3>
<div>
<ul class="marker odd">
<li class="marker">WI-9028 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=9407%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=9407">UniSTS:9407</a></li></ul></li>
</ul>
<ul class="marker ">
<li class="marker">WI-19271 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=3828%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=3828">UniSTS:3828</a></li></ul></li>
</ul>
</div>
</div>
<div></div>
<div class="infosec">
<h3 id="homology">
<a class="jig-ncbitoggler-open">Homology</a>
</h3>
<ul class="geneinfo-subsec">
<li>
<a href="/gene/10945/ortholog/" id="ncbi-ortholog-link">NCBI Orthologs</a>
</li>
<a href="https://www.orthodb.org/?ncbi=10945" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8178" target="_blank">
Orthologs from OrthoDB
</a>
</ul>
</div>
<!--<component id="Gene_InfoPathway"/>-->
<div class="gene-ontology infosec">
<h3 id="gene-ontology">
<a class="jig-ncbitoggler-open">
<span>Gene Ontology</span>
</a>
<a target="_blank" href="http://www.ebi.ac.uk/GOA" class="g-ontology-src" title="Provided by GOA">Provided by GOA</a>
</h3>
<div class="ontology-tables">
<div class="ui-ncbigrid-outer-div">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
<thead>
<tr>
<th class="col1">Function</th>
<th style="width:12%;">Evidence Code</th>
<th style="width:10%;">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0046923">enables ER retention sequence binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-1-0" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005046">enables KDEL sequence binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-2-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/8392934,18086916" target="_blank" title="PubMed ID 8392934,18086916" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=8392934,18086916">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-func">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005515">enables protein binding</a>
</td>
<td headers="ont-evi- ont-evi-code-">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
<div id="evidence-code-3-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi- ont-pub-"><a href="/pubmed/32296183" target="_blank" title="PubMed ID 32296183" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=32296183">PubMed</a> </td>
</tr>
</tbody>
</table>
</div>
</div>
<div class="ui-ncbigrid-outer-div">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
<thead>
<tr>
<th class="col1">Process</th>
<th style="width:12%;">Evidence Code</th>
<th style="width:10%;">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0070231">involved_in T cell apoptotic process</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-1-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0030217">involved_in T cell differentiation</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-2-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0006621">involved_in protein retention in ER lumen</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-3-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0015031">involved_in protein transport</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
<div id="evidence-code-4-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"> </td>
</tr>
<tr>
<td headers="ont-comp">
<a href="http://amigo.geneontology.org/amigo/term/GO:0006890">involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum</a>
</td>
<td headers="ont-evi-2 ont-evi-code-2">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-5-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/8392934,18086916" target="_blank" title="PubMed ID 8392934,18086916" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=8392934,18086916">PubMed</a> </td>
</tr>
</tbody>
</table>
</div>
</div>
<div class="ui-ncbigrid-outer-div">
<div class="ui-ncbigrid-inner-div">
<table class="jig-ncbigrid" data-config="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
<thead>
<tr>
<th class="col1">Component</th>
<th style="width:12%;">Evidence Code</th>
<th style="width:10%;">Pubs</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0030663">colocalizes_with COPI-coated vesicle membrane</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-1-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/18086916" target="_blank" title="PubMed ID 18086916" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=18086916">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0000139">located_in Golgi membrane</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-2-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/8392934,18086916" target="_blank" title="PubMed ID 8392934,18086916" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=8392934,18086916">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0000139">located_in Golgi membrane</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-3-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005801">is_active_in cis-Golgi network</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-4-2" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005783">is_active_in endoplasmic reticulum</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
<div id="evidence-code-5-2" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005789">located_in endoplasmic reticulum membrane</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-6-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/8392934,18086916" target="_blank" title="PubMed ID 8392934,18086916" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=8392934,18086916">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005789">located_in endoplasmic reticulum membrane</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-7-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0005793">located_in endoplasmic reticulum-Golgi intermediate compartment</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-8-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
<div id="evidence-code-8-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/15308636" target="_blank" title="PubMed ID 15308636" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=15308636">PubMed</a> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0033116">located_in endoplasmic reticulum-Golgi intermediate compartment membrane</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-9-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-9-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
<tr>
<td headers="ont-proc">
<a href="http://amigo.geneontology.org/amigo/term/GO:0030133">located_in transport vesicle</a>
</td>
<td headers="ont-evi-3 ont-evi-code-3">
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-10-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
<div id="evidence-code-10-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
</td>
<td headers="ont-evi-3 ont-pub-3"> </td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
</div>
</div>
</div>
<div class="rprt-section gene-general-protein-info">
<section class="rprt-section-header" id="general-protein-info">
<h2 id="header-general-protein-info">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-protein-info .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">General protein information</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.General_Protein_Information" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<dl>
<dt>Preferred Names</dt>
<dd>ER lumen protein-retaining receptor 1</dd>
</dl>
<dl>
<dt>Names</dt>
<dd>KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1</dd>
<dd>KDEL receptor 1</dd>
<dd>putative MAPK-activating protein PM23</dd>
</dl>
</div>
</div>
<div class="rprt-section gene-reference-sequences">
<section class="rprt-section-header" id="reference-sequences">
<h2 id="header-reference-sequences">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-reference-sequences .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">NCBI Reference Sequences (RefSeq)</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.NCBI_Reference_Sequences_RefS" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<p>
<span class="new-icon">NEW</span>
<strong>Try the new <a href="/datasets/tables/genes/?table_type=transcripts&amp;ids=10945&amp;utm_source=gene&amp;utm_medium=referral&amp;utm_campaign=refseq" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report." data-ga-category="refseq" data-ga-action="click_datasets_link" data-ga-label="transcript_table">Transcript table</a></strong>
</p>
<h3 class="genomerefseqs gene_std_toggler" id="refseqset-independent">
<a class="jig-ncbitoggler-open">RefSeqs maintained independently of Annotated
Genomes</a>
</h3>
<div class="genomerefseqs_slave">
<p class="desc"> These reference sequences exist independently of genome builds. <a href="#refseq-expl" id="expl-refseg">Explain</a></p>
<p id="refseq-expl"> These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in <a href="#geneGenomic regions, transcripts, and products">Genomic regions,
transcripts, and products</a> above. </p>
<h4 id="mrnaandproteins-p195823536">mRNA and Protein(s) </h4>
<ol>
<li>
<p><a href="/nuccore/NM_006801.3">NM_006801.3</a><a href="/protein/NP_006792.1">NP_006792.1</a>  ER lumen protein-retaining receptor 1</p>
<p>
<a href="/ipg/NP_006792.1/" ref="ncbi_uid=10945">See identical proteins and their annotated locations for NP_006792.1</a>
</p>
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
<dl>
<dt>Source sequence(s)</dt>
<dd class="wordwrap">
<a href="/nuccore/BC018778">BC018778</a>
</dd>
<dt>Consensus CDS</dt>
<dd>
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&amp;GO=MainBrowse&amp;DATA=CCDS12718.1">CCDS12718.1</a>
</dd>
<dt>UniProtKB/Swiss-Prot</dt>
<dd><a href="https://www.uniprot.org/uniprot/B2R6N4" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=10945&amp;nlmid=&amp;db=gene">B2R6N4</a>, <a href="https://www.uniprot.org/uniprot/P24390" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=10945&amp;nlmid=&amp;db=gene">P24390</a>, <a href="https://www.uniprot.org/uniprot/Q54A39" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=10945&amp;nlmid=&amp;db=gene">Q54A39</a>, <a href="https://www.uniprot.org/uniprot/Q8NBW7" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=10945&amp;nlmid=&amp;db=gene">Q8NBW7</a></dd>
<dt>Related</dt>
<dd><a href="http://www.ensembl.org/id/ENSP00000329471.2" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=10945&amp;nlmid=&amp;db=gene">ENSP00000329471.2</a>, <a href="http://www.ensembl.org/id/ENST00000330720.7" ref="itool=Gene_FullReport&amp;PrId=5380&amp;uid=10945&amp;nlmid=&amp;db=gene">ENST00000330720.7</a></dd>
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_006792.1">summary</a></dt>
<dd>
<dl class="level2">
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=395652">pfam00810</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">28</span><span class="cddto">169</span></dt>
<dd class="clearfix"> ER_lumen_recept; ER lumen protein retaining receptor</dd>
</dl>
</dd>
</dl>
</li>
</ol>
</div>
<h3 class="genomerefseqs gene_std_toggler" id="annotatedrefseq-title">
<a class="jig-ncbitoggler-open">RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08</a>
</h3>
<div class="genomerefseqs_slave">
<p class="desc"> The following sections contain reference sequences that belong to a
specific genome build. <a href="#" id="expl-genomes">Explain</a></p>
<p id="expl-genomes-desc" style="display:none">This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.</p>
<h3 id="refseq-sequencedescription-p132174416">Reference GRCh38.p14 Primary Assembly</h3>
<h4 id="genomic-p132174416">Genomic </h4>
<ol>
<li>
<p>NC_000019.10 Reference GRCh38.p14 Primary Assembly</p>
<dl>
<dt>Range</dt>
<dd class="rs-range">
<span>48382575..48397412 complement</span>
</dd>
<dt>Download</dt>
<dd><a href="/nuccore/NC_000019.10?from=48382575&amp;to=48397412&amp;report=genbank&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=NC_000019.10?from=48382575&amp;to=48397412&amp;report=genbank&amp;strand=true">GenBank</a>, <a href="/nuccore/NC_000019.10?from=48382575&amp;to=48397412&amp;report=fasta&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=NC_000019.10?from=48382575&amp;to=48397412&amp;report=fasta&amp;strand=true">FASTA</a>, <a href="/nuccore/NC_000019.10?from=48380348&amp;to=48399637&amp;report=graph&amp;content=5&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=NC_000019.10?from=48380348&amp;to=48399637&amp;report=graph&amp;content=5&amp;strand=true">Sequence Viewer (Graphics)</a></dd>
</dl>
</li>
</ol>
<h4 id="mrnaandproteins-p104097168">mRNA and Protein(s) </h4>
<ol>
<li>
<p><a href="/nuccore/XM_047438095.1">XM_047438095.1</a><a href="/protein/XP_047294051.1">XP_047294051.1</a>  ER lumen protein-retaining receptor 1 isoform X1</p>
<dl></dl>
</li>
</ol>
<h3 id="refseq-sequencedescription-p109199936">Alternate T2T-CHM13v2.0</h3>
<h4 id="genomic-p109199936">Genomic </h4>
<ol>
<li>
<p>NC_060943.1 Alternate T2T-CHM13v2.0</p>
<dl>
<dt>Range</dt>
<dd class="rs-range">
<span>51376721..51392513 complement</span>
</dd>
<dt>Download</dt>
<dd><a href="/nuccore/NC_060943.1?from=51376721&amp;to=51392513&amp;report=genbank&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=NC_060943.1?from=51376721&amp;to=51392513&amp;report=genbank&amp;strand=true">GenBank</a>, <a href="/nuccore/NC_060943.1?from=51376721&amp;to=51392513&amp;report=fasta&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=NC_060943.1?from=51376721&amp;to=51392513&amp;report=fasta&amp;strand=true">FASTA</a>, <a href="/nuccore/NC_060943.1?from=51374351&amp;to=51394881&amp;report=graph&amp;content=5&amp;strand=true" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=NC_060943.1?from=51374351&amp;to=51394881&amp;report=graph&amp;content=5&amp;strand=true">Sequence Viewer (Graphics)</a></dd>
</dl>
</li>
</ol>
<h4 id="mrnaandproteins-p194376624">mRNA and Protein(s) </h4>
<ol>
<li>
<p><a href="/nuccore/XM_054319623.1">XM_054319623.1</a><a href="/protein/XP_054175598.1">XP_054175598.1</a>  ER lumen protein-retaining receptor 1 isoform X1</p>
<dl></dl>
</li>
</ol>
</div>
</div>
</div>
<div class="rprt-section gene-related-sequences">
<section class="rprt-section-header" id="related-sequences">
<h2 id="header-related-sequences">
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-related-sequences .rprt-section-body'">
<span class="ui-ncbitoggler-master-text">Related sequences</span>
</a>
</h2>
<div class="rprt-section-tools">
<a href="#top" title="Go to the top of the page" class="gene-top-page">
<span>Go to the top of the page</span>
</a>
<a href="/books/NBK3841/#EntrezGene.Related_Sequences" title="Help" class="gene-section-help">
<span>Help</span>
</a>
</div>
</section>
<div class="rprt-section-body">
<div>
<table id="proteinTblId" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/10945/data/related-sequences/',webserviceParams: 'p$l=Ajax', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
<thead>
<tr>
<th colspan="2" id="rs-nucleo">Nucleotide</th>
<th rowspan="2" id="rs-protein">Protein</th>
</tr>
<tr>
<th id="rs-heading">Heading</th>
<th id="rs-heading-acc">Accession and Version</th>
</tr>
</thead>
<tbody></tbody>
</table>
<table id="proteinTblId" class="jig-ncbigrid" data-jigconfig="isPageable:true, pageSize:25">
<thead>
<tr>
<th class="proteinTblTh" rowspan="2" id="rs-prot-acc">Protein Accession</th>
<th class="proteinTblTh" colspan="2" id="rs-link">Links</th>
</tr>
<tr>
<th id="rs-genepept">GenPept Link</th>
<th id="rs-uniprot">UniProtKB Link</th>
</tr>
</thead>
<tbody>
<tr>
<td headers="rs-prot-acc">P24390.1</td>
<td headers="rs-link rs-genepept">
<a href="/protein/119543" ref="ordinalpos=1&amp;ncbi_uid=10945&amp;link_uid=119543">GenPept</a>
</td>
<td>
<a href="https://www.uniprot.org/uniprot/P24390">UniProtKB/Swiss-Prot:P24390</a>
</td>
</tr>
</tbody>
</table>
</div>
</div>
</div>
<div class="rprt-section gene-additional-links">
<section class="rprt-section-header" id="additional-links"><h2 id="header-additional-links"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-additional-links .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Additional links</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Additional_Links" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
<div class="rprt-section-body" style="">
<h3 class="withnote" id="genelinkout">
<a class="jig-ncbitoggler">Gene LinkOut</a>
</h3><div>
<p>The following <a href="https://www.ncbi.nlm.nih.gov/projects/linkout/index.html">LinkOut</a> resources are supplied by external providers. These providers are responsible for maintaining the links. </p>
<div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Chemical Information</span>
</a>
<ul>
<li><span class="free-rsc"></span>Interologous Interaction Database</li>
<ul>
<li>
<a target="_blank" href="http://ophid.utoronto.ca/redirect/ncbi/human?proteins=10945" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7911">
<span>Interologous Interaction Database</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>MilliporeSigma</li>
<ul>
<li>
<a target="_blank" href="https://www.sigmaaldrich.com/catalog/genes/KDELR1?lang=en&amp;region=US" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9978">
<span>KDELR1 products</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Molecular Biology Databases</span>
</a>
<ul>
<li><span class="free-rsc"></span>Bgee database</li>
<ul>
<li>
<a target="_blank" href="https://www.bgee.org/gene/ENSG00000105438" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10418">
<span>KDELR1 gene expression</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>BioGPS</li>
<ul>
<li>
<a target="_blank" href="http://biogps.org/gene/10945/" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5059">
<span>BioGPS</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>BioGRID Open Repository of CRISPR Screens (ORCS)</li>
<ul>
<li>
<a target="_blank" href="https://orcs.thebiogrid.org/Gene/10945" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10164">
<span>BioGRID CRISPR Screen Phenotypes (34 hits/1352 screens)</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>CTD: Comparative Toxicogenomics Database</li>
<ul>
<li>
<a target="_blank" href="http://ctdbase.org/detail.go?type=gene&amp;acc=10945" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7845">
<span>CTD: Comparative Toxicogenomics Database - KDELR1</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Domain Mapping of Disease Mutations</li>
<ul>
<li>
<a target="_blank" href="http://bioinf.umbc.edu/DMDM/gene_prot_page.php?id=10945" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7642">
<span>KDELR1</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Eukaryotic Promoter Database</li>
<ul>
<li>
<a target="_blank" href="http://epd.vital-it.ch/cgi-bin/get_doc?db=hgEpdNew&amp;format=genome&amp;entry=KDELR1_1" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9624">
<span>KDELR1_1</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>GlyGen glycoinformatics resource</li>
<ul>
<li>
<a target="_blank" href="https://glygen.org/protein/P24390" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=10227">
<span>GlyGen glycoinformatics resource</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Human eFP Browser</li>
<ul>
<li>
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Nervous&amp;modeInput=Absolute&amp;primaryGene=10945" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8875">
<span>Human eFP Browser</span>
</a>
</li>
<li>
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Skeletal_Immune_Digestive&amp;modeInput=Absolute&amp;primaryGene=10945" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8875">
<span>Human eFP Browser</span>
</a>
</li>
<li>
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Reproductive&amp;modeInput=Absolute&amp;primaryGene=10945" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8875">
<span>Human eFP Browser</span>
</a>
</li>
</ul>
<li>Ingenuity Pathways Analysis</li>
<ul>
<li>
<a target="_blank" href="http://partnersolution.ingenuity.com/?cid=97ae3f91eab87a&amp;p1=Entrez&amp;p2=GV&amp;s=&amp;ipaUri=%2Fpa%2Fapi%2Fv2%2Fgeneview%3Fapplicationname%3DEntrez%26geneId%3D10945%26geneidtype%3Dentrezgene" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5628">
<span>Ingenuity Pathways Analysis</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>InnateDB</li>
<ul>
<li>
<a target="_blank" href="http://www.innatedb.com/getGeneCard.do?id=60399" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7894">
<span>InnateDB</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>InterMine</li>
<ul>
<li>
<a target="_blank" href="https://www.humanmine.org/humanmine/search?keyword=ENSG00000105438" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9169">
<span>InterMine</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>Kyoto Encyclopedia of Genes and Genomes</li>
<ul>
<li>
<a target="_blank" href="http://www.genome.jp/dbget-bin/www_bget?hsa:10945" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5174">
<span>Kyoto Encyclopedia of Genes and Genomes</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>OMA Browser: Orthologous MAtrix</li>
<ul>
<li>
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN44798/" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=9822">
<span>OMA Browser: Orthologous MAtrix</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>OrthoDB catalog of orthologs</li>
<ul>
<li>
<a target="_blank" href="https://www.orthodb.org/?ncbi=10945" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8178">
<span>Orthologs</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>PhosphoSitePlus</li>
<ul>
<li>
<a target="_blank" href="https://www.phosphosite.org/entrezGeneIdAction.action?id=10945" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7987">
<span>PhosphoSitePlus® - comprehensive post-translational modification resource</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>The Gene Wiki</li>
<ul>
<li>
<a target="_blank" href="https://en.wikipedia.org/wiki/KDELR1" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=6933">
<span>The Gene Wiki</span>
</a>
</li>
</ul>
<li><span class="free-rsc"></span>The Weizmann Institute of Science GeneCards and MalaCards databases</li>
<ul>
<li>
<a target="_blank" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=KDELR1" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8598">
<span>GeneCard for KDELR1</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Research Materials</span>
</a>
<ul>
<li><span class="order-rsc"></span>Addgene Non-profit plasmid repository</li>
<ul>
<li>
<a target="_blank" href="https://addgene.org//browse/gene/10945" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5304">
<span>Get Plasmids - Addgene</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>Bio-Techne</li>
<ul>
<li>
<a target="_blank" href="https://www.bio-techne.com/t/kdelr1/antibodies?utm_source=linkout&amp;utm_medium=referral&amp;utm_campaign=product&amp;utm_term=antibodies" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8242">
<span>KDELR1 Antibodies</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.bio-techne.com/t/kdelr1/lysates?utm_source=linkout&amp;utm_medium=referral&amp;utm_campaign=product&amp;utm_term=lysates" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8242">
<span>KDELR1 Lysates</span>
</a>
</li>
</ul>
<li>ExactAntigen/Labome</li>
<ul>
<li>
<a target="_blank" href="https://www.labome.com/gene/human/KDELR1-antibody.html" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=5753">
<span>reagents</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>GenScript latest version of gene cDNA ORF Clone</li>
<ul>
<li>
<a target="_blank" href="http://www.genscript.com/gene/10945" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8012">
<span>GenScript latest version of gene cDNA ORF Clone</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>GeneCopoeia Inc.</li>
<ul>
<li>
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=22&amp;field=5&amp;key=10945" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7255">
<span>Order promoter clone</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=11&amp;field=5&amp;key=10945" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7255">
<span>Order shRNA clones</span>
</a>
</li>
<li>
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=1&amp;field=5&amp;key=10945" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7255">
<span>Order full-length ORF clone</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>GeneTex Inc</li>
<ul>
<li>
<a target="_blank" href="https://www.genetex.com/Product/Search?geneid=10945&amp;type=01&amp;page=1" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=8117">
<span>Find Quality Antibodies</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>Kazusa DNA Research Institute</li>
<ul>
<li>
<a target="_blank" href="http://www.kazusa.or.jp/kop/dsearch/symsearch.cgi?keyword=KDELR1;" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=3267">
<span>Kazusa DNA Research Institute</span>
</a>
</li>
</ul>
<li><span class="order-rsc"></span>OriGene</li>
<ul>
<li>
<a target="_blank" href="https://www.origene.com/search?q=Kdelr1" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7994">
<span>Order Kdelr1 cDNA clone/Protein/Antibody/RNAi</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open main">
<span>Tools</span>
</a>
<ul>
<li><span class="free-rsc"></span>GeneMANIA</li>
<ul>
<li>
<a target="_blank" href="http://genemania.org/link?o=9606&amp;g=10945" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=7529">
<span>GeneMANIA</span>
</a>
</li>
</ul>
</ul>
</div>
<div class="linkout">
<a class="jig-ncbitoggler-open">
<span>Miscellaneous</span>
</a>
<ul>
<li><span class="free-rsc"></span>Reactome</li>
<ul>
<li>
<a target="_blank" href="https://reactome.org/content/query?q=UniProt:P24390" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=4914">
<span>Reactome Entity:P24390</span>
</a>
</li>
<li>
<a target="_blank" href="https://reactome.org/PathwayBrowser/#/R-HSA-5653656" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=4914">
<span>Reactome Event:Vesicle-mediated transport</span>
</a>
</li>
<li>
<a target="_blank" href="https://reactome.org/PathwayBrowser/#/R-HSA-392499" ref="itool=Gene_FullReport&amp;uid=10945&amp;nlmid=&amp;db=gene&amp;log$=linkoutlink&amp;PrId=4914">
<span>Reactome Event:Metabolism of proteins</span>
</a>
</li>
</ul>
</ul>
</div>
</div>
</div>
<div id="urls-in-genombrowser" style="display:none">
</div>
</div>
</div>
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</div>
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<!-- sidebar close/hide button-->
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<h2 class="offscreen_noflow">Supplemental Content</h2>
<div id="gene-sidebar">
<div>
<div class="portlet brieflink dis-table-of-contents">
<div class="portlet_head">
<div class="portlet_title">
<h3>Table of contents</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_TableOfContents" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter"></a>
</div>
<div class="portlet_content">
<ul>
<li class="">
<a href="#summary">Summary</a>
</li>
<li class="">
<a href="#genomic-context">Genomic context</a>
</li>
<li class="">
<a href="#genomic-regions-transcripts-products">Genomic regions, transcripts, and products</a>
</li>
<li class="">
<a href="#gene-expression">Expression</a>
</li>
<li class="">
<a href="#bibliography">Bibliography</a>
</li>
<li class="">
<a href="#phenotypes">Phenotypes</a>
</li>
<li class="">
<a href="#variation">Variation</a>
</li>
<li class="">
<a href="#pathways">Pathways from PubChem</a>
</li>
<li class="">
<a href="#interactions">Interactions</a>
</li>
<li class="">
<a href="#general-gene-info">General gene information</a>
<div class="subsection-links"><a href="#gene-markers">Markers</a>, <a href="#homology">Homology</a>, <a href="#gene-ontology">Gene Ontology</a></div>
</li>
<li class="">
<a href="#general-protein-info">General protein information</a>
</li>
<li class="">
<a href="#reference-sequences">NCBI Reference Sequences (RefSeq)</a>
</li>
<li class="">
<a href="#related-sequences">Related sequences</a>
</li>
<li class="">
<a href="#additional-links">Additional links</a>
</li>
</ul>
</div>
</div>
<div class="portlet brieflink dis-genomesbrowser brieflink dis-genomesbrowser">
<div class="portlet_head">
<div class="portlet_title">
<h3>Genome Browsers</h3>
</div>
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<div class="portlet_content">
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<li>
<a href="#">Loading...</a>
</li>
</ul>
</div>
</div>
<div class="portlet dis-related-info brieflink">
<div class="portlet_head">
<div class="portlet_title">
<h3>Related information</h3>
</div>
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="discovery_db_links" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter"></a>
</div>
<div class="portlet_content DiscoveryDbLinks">
<ul>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/clone/order/gene/10945" ref="log$=recordlinks">Order cDNA clone</a>
<div class="brieflinkpop offscreen_noflow">Order cDNA clone</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_alltarget_list&amp;from_uid=10945" ref="log$=recordlinks">BioAssay by Target (List)</a>
<div class="brieflinkpop offscreen_noflow">BioAssays related to the gene by protein target or RNAi target</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="//pubchem.ncbi.nlm.nih.gov/assay/bioactivity.html?geneid=10945" ref="log$=recordlinks">BioAssay by Target (Summary)</a>
<div class="brieflinkpop offscreen_noflow">Summarized PubChem Data on the gene, showing the active data by default</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_target&amp;from_uid=10945" ref="log$=recordlinks">BioAssay, by Gene target</a>
<div class="brieflinkpop offscreen_noflow">PubChem BioAssays done on the Gene target</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_rnai_active&amp;from_uid=10945" ref="log$=recordlinks">BioAssays, RNAi Target, Active</a>
<div class="brieflinkpop offscreen_noflow">BioAssays that contain the gene as the target of a RNAi reagent, which is identified as a hit in a RNAi screening and flagged as "active" in the corresponding BioAssay record</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_rnai&amp;from_uid=10945" ref="log$=recordlinks">BioAssays, RNAi Target, Tested</a>
<div class="brieflinkpop offscreen_noflow">BioAssays that contain the gene as the target of a RNAi reagent</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/bioproject?LinkName=gene_bioproject&amp;from_uid=10945" ref="log$=recordlinks">BioProjects</a>
<div class="brieflinkpop offscreen_noflow">BioProjects related to a gene</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/biosystems?LinkName=gene_biosystems&amp;from_uid=10945" ref="log$=recordlinks">BioSystems</a>
<div class="brieflinkpop offscreen_noflow">BioSystems</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/CCDS/CcdsBrowse.cgi?REQUEST=GENEID&amp;DATA=10945" ref="log$=recordlinks">CCDS</a>
<div class="brieflinkpop offscreen_noflow">Link to CCDS</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar&amp;from_uid=10945" ref="log$=recordlinks">ClinVar</a>
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/cdd?LinkName=gene_cdd&amp;from_uid=10945" ref="log$=recordlinks">Conserved Domains</a>
<div class="brieflinkpop offscreen_noflow">Related CDD</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/dbvar?LinkName=gene_dbvar&amp;from_uid=10945" ref="log$=recordlinks">dbVar</a>
<div class="brieflinkpop offscreen_noflow">Link from Gene to dbVar</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc&amp;from_uid=10945" ref="log$=recordlinks">Full text in PMC</a>
<div class="brieflinkpop offscreen_noflow">PMC links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc_nucleotide&amp;from_uid=10945" ref="log$=recordlinks">Full text in PMC_nucleotide</a>
<div class="brieflinkpop offscreen_noflow">Full text in PubMedCentral identified from shared sequence links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/sparcle?LinkName=gene_sparcle&amp;from_uid=10945" ref="log$=recordlinks">Functional Class</a>
<div class="brieflinkpop offscreen_noflow">Functional class of the sequence domain architecture</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_neighbors&amp;from_uid=10945" ref="log$=recordlinks">Gene neighbors</a>
<div class="brieflinkpop offscreen_noflow">Overlapping genes and two nearest non-overlapping genes on either side</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_h3k4me3&amp;from_uid=10945" ref="log$=recordlinks">Genes with a similar H3K4me3 profile</a>
<div class="brieflinkpop offscreen_noflow">Genes with a similar profile of promoter-activating H3K4me3 modifications across several tissue types</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/genome?LinkName=gene_genome&amp;from_uid=10945" ref="log$=recordlinks">Genome</a>
<div class="brieflinkpop offscreen_noflow">Related Genome</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/geoprofiles?LinkName=gene_geoprofiles&amp;from_uid=10945" ref="log$=recordlinks">GEO Profiles</a>
<div class="brieflinkpop offscreen_noflow">Related GEO</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/gtr/tests/?term=10945[geneid]" ref="log$=recordlinks">GTR</a>
<div class="brieflinkpop offscreen_noflow">Tests for this gene in the NIH Genetic Testing Registry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/homologene?LinkName=gene_homologene&amp;from_uid=10945" ref="log$=recordlinks">HomoloGene</a>
<div class="brieflinkpop offscreen_noflow">Related HomoloGene</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore&amp;from_uid=10945" ref="log$=recordlinks">Nucleotide</a>
<div class="brieflinkpop offscreen_noflow">Link to related Nucleotide entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/omim?LinkName=gene_omim&amp;from_uid=10945" ref="log$=recordlinks">OMIM</a>
<div class="brieflinkpop offscreen_noflow">Link to related OMIM entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/probe?LinkName=gene_probe&amp;from_uid=10945" ref="log$=recordlinks">Probe</a>
<div class="brieflinkpop offscreen_noflow">Related Probe entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein&amp;from_uid=10945" ref="log$=recordlinks">Protein</a>
<div class="brieflinkpop offscreen_noflow">Link to related protein entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pccompound?LinkName=gene_pccompound&amp;from_uid=10945" ref="log$=recordlinks">PubChem Compound</a>
<div class="brieflinkpop offscreen_noflow">PubChem Compounds</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pcsubstance?LinkName=gene_pcsubstance&amp;from_uid=10945" ref="log$=recordlinks">PubChem Substance</a>
<div class="brieflinkpop offscreen_noflow">PubChem Substances</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed&amp;from_uid=10945" ref="log$=recordlinks">PubMed</a>
<div class="brieflinkpop offscreen_noflow">Link to related PubMed entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_rif&amp;from_uid=10945" ref="log$=recordlinks">PubMed (GeneRIF)</a>
<div class="brieflinkpop offscreen_noflow">Link to related PubMed article from GeneRIFs</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_citedinomim&amp;from_uid=10945" ref="log$=recordlinks">PubMed (OMIM)</a>
<div class="brieflinkpop offscreen_noflow">Gene links to PubMed derived from omim_pubmed_cited links</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_pmc_nucleotide&amp;from_uid=10945" ref="log$=recordlinks">PubMed(nucleotide/PMC)</a>
<div class="brieflinkpop offscreen_noflow">Citations in PubMed identified from shared sequence and PMC links.</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein_refseq&amp;from_uid=10945" ref="log$=recordlinks">RefSeq Proteins</a>
<div class="brieflinkpop offscreen_noflow">Link to Protein RefSeqs</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore_refseqrna&amp;from_uid=10945" ref="log$=recordlinks">RefSeq RNAs</a>
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeq RNAs</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/snp?LinkName=gene_snp&amp;from_uid=10945" ref="log$=recordlinks">SNP</a>
<div class="brieflinkpop offscreen_noflow">Related SNP records</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/taxonomy?LinkName=gene_taxonomy&amp;from_uid=10945" ref="log$=recordlinks">Taxonomy</a>
<div class="brieflinkpop offscreen_noflow">Link to related taxonomy entry</div>
</li>
<li class="brieflinkpopper">
<a class="brieflinkpopperctrl" href="/variation/view/?q=10945[geneid]" ref="log$=recordlinks">Variation Viewer</a>
<div class="brieflinkpop offscreen_noflow">Related Variants</div>
</li>
</ul>
</div>
</div>
<div class="portlet dis-links-to-other-res brieflink">
<div class="portlet_head">
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<h3>Links to other resources</h3>
</div>
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<div class="portlet_content">
<ul>
<li>
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6304">HGNC</a>
</li>
<li>
<a href="http://www.ensembl.org/id/ENSG00000105438">Ensembl</a>
</li>
<li>
<a href="https://www.alliancegenome.org/gene/HGNC:6304">AllianceGenome</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=geneid&amp;org=9606&amp;l=10945">AceView</a>
</li>
<li>
<a href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&amp;position=NM_006801">UCSC</a>
</li>
<li>
<a href="https://genecollections.nci.nih.gov/MGC/?ORG=Hs&amp;LIST=BC008958,BC018778">MGC</a>
</li>
<li>
<a href="http://www.genome.jp/dbget-bin/www_bget?hsa:10945">KEGG</a>
</li>
<li>
<a href="https://reactome.org/content/query?q=UniProt:P24390">Reactome</a>
</li>
</ul>
</div>
</div>
<div class="portlet brieflink dis-general-info">
<div class="portlet_head">
<div class="portlet_title">
<h3>General information</h3>
</div>
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<ul>
<li>
<a href="/pmc/?term=PMC4383897+OR+PMC3013746+OR+PMC1761442+OR+PMC539985">About Gene</a>
</li>
<li>
<a href="/books/NBK3840">FAQ</a>
</li>
<li>
<a href="https://ftp.ncbi.nlm.nih.gov/gene/">FTP site</a>
</li>
<li>
<a href="/books/NBK3841/">Help</a>
</li>
<li>
<a href="/books/NBK3842/">My NCBI help</a>
</li>
<li>
<a href="/books/NBK21085/">NCBI Handbook</a>
</li>
<li>
<a href="/gene/statistics/">Statistics</a>
</li>
</ul>
</div>
</div>
<div class="portlet brieflink dis-related-sites">
<div class="portlet_head">
<div class="portlet_title">
<h3>Related sites</h3>
</div>
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<li>
<a href="https://www.ncbi.nlm.nih.gov/BLAST">BLAST</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/genome">Genome</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/bioproject">BioProject</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/genome/gdv/">Genome Data Viewer</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/geo">GEO</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/omim">OMIM</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/probe">Probe</a>
</li>
<li>
<a href="https://www.ncbi.nlm.nih.gov/RefSeq">RefSeq</a>
</li>
</ul>
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<a href="https://support.ncbi.nlm.nih.gov/ics/support/ticketnewwizard.asp?style=classic&amp;deptID=28049">Contact Help Desk</a>
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<li>
<a href="https://www.ncbi.nlm.nih.gov/RefSeq/update.cgi?geneid=10945&amp;symbol=KDELR1">Submit Correction</a>
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<li>
<a href="/gene/submit-generif?geneId=10945&amp;sym=KDELR1&amp;name=KDEL endoplasmic reticulum protein retention receptor 1&amp;org=Homo sapiens">Submit GeneRIF</a>
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<a href="https://www.ncbi.nlm.nih.gov/mailman/listinfo/refseq-announce">RefSeq</a>
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<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67d419072f30673f7b5bf58c">KDELR1 KDEL endoplasmic reticulum protein retention receptor 1 [Homo sapiens]</a>
<div class="ralinkpop offscreen_noflow">KDELR1 KDEL endoplasmic reticulum protein retention receptor 1 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:10945</div></div>
<div class="tertiary">Gene</div>
</li>
<li class="ra_rcd ralinkpopper two_line">
<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=2" href="/portal/utils/pageresolver.fcgi?recordid=67d41906cde49f3df737653d">LOC130064854 [Homo sapiens]</a>
<div class="ralinkpop offscreen_noflow">LOC130064854 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:130064854</div></div>
<div class="tertiary">Gene</div>
</li>
<li class="ra_rcd ralinkpopper two_line">
<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=3" href="/portal/utils/pageresolver.fcgi?recordid=67d419052f30673f7b5be8cf">LOC130064853 [Homo sapiens]</a>
<div class="ralinkpop offscreen_noflow">LOC130064853 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:130064853</div></div>
<div class="tertiary">Gene</div>
</li>
<li class="ra_rcd ralinkpopper two_line">
<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=4" href="/portal/utils/pageresolver.fcgi?recordid=67d419032f30673f7b5bdeb3">SYNGR4 synaptogyrin 4 [Homo sapiens]</a>
<div class="ralinkpop offscreen_noflow">SYNGR4 synaptogyrin 4 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:23546</div></div>
<div class="tertiary">Gene</div>
</li>
<li class="ra_rcd ralinkpopper two_line">
<a class="htb ralinkpopperctrl" ref="log$=activity&amp;linkpos=5" href="/portal/utils/pageresolver.fcgi?recordid=67d4190267c23b31e0169659">LOC127891908 [Homo sapiens]</a>
<div class="ralinkpop offscreen_noflow">LOC127891908 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:127891908</div></div>
<div class="tertiary">Gene</div>
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