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2731 lines
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231 KiB
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<h1 class="res_name"><a href="/gene/">Gene</a></h1>
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<h2 class="res_tagline">Genes and mapped phenotypes</h2>
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<div class="search"><div class="search_form"><label for="database" class="offscreen_noflow">Search database</label><select id="database"><optgroup label="Recent"><option value="pubmed">PubMed</option><option value="clinvar">ClinVar</option><option value="medgen">MedGen</option><option value="books" class="last">Books</option></optgroup><optgroup label="All"><option value="gquery">All Databases</option><option value="assembly" data-ac_dict="assembly">Assembly</option><option value="biocollections">Biocollections</option><option value="bioproject">BioProject</option><option value="biosample">BioSample</option><option value="books">Books</option><option value="clinvar">ClinVar</option><option value="cdd">Conserved Domains</option><option value="gap">dbGaP</option><option value="dbvar">dbVar</option><option value="gene" selected="selected" data-ac_dict="gene">Gene</option><option value="genome" data-ac_dict="genome">Genome</option><option value="gds">GEO DataSets</option><option value="geoprofiles">GEO Profiles</option><option value="gtr">GTR</option><option value="ipg">Identical Protein Groups</option><option value="medgen">MedGen</option><option value="mesh">MeSH</option><option value="nlmcatalog">NLM Catalog</option><option value="nuccore" data-ac_dict="nuccore">Nucleotide</option><option value="omim">OMIM</option><option value="pmc">PMC</option><option value="protein" data-ac_dict="protein">Protein</option><option value="proteinclusters">Protein Clusters</option><option value="protfam">Protein Family Models</option><option value="pcassay">PubChem BioAssay</option><option value="pccompound">PubChem Compound</option><option value="pcsubstance">PubChem Substance</option><option value="pubmed">PubMed</option><option value="snp">SNP</option><option value="sra">SRA</option><option value="structure">Structure</option><option value="taxonomy">Taxonomy</option><option value="toolkit">ToolKit</option><option value="toolkitall">ToolKitAll</option><option value="toolkitbookgh">ToolKitBookgh</option></optgroup></select><div class="nowrap"><label for="term" class="offscreen_noflow" accesskey="/">Search term</label><div class="nowrap"><input type="text" name="term" id="term" title="Search Gene. Use up and down arrows to choose an item from the autocomplete." value="" class="jig-ncbiclearbutton jig-ncbiautocomplete" data-jigconfig="dictionary:'gene',disableUrl:'NcbiSearchBarAutoComplCtrl'" autocomplete="off" data-sbconfig="ds:'no',pjs:'yes',afs:'yes'" /></div><button id="search" type="submit" class="button_search nowrap" cmd="go">Search</button></div></div><ul class="searchlinks inline_list"><set></set><li><a href="/gene/advanced">Advanced</a></li><li class="help"><a id="help" class="jig-ncbihelpwindow" target="ncbihelp" name="help" href="/books/NBK3841/">Help</a></li></ul></div>
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<input name="EntrezSystem2.PEntrez.Gene.Gene_PageController.PreviousPageName" sid="1" type="hidden" value="results" />
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<h2 class="offscreen_noflow">Result Filters</h2>
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<div class="facet_cont" data-db="gene" data-default_grps="fg_gene-sources,fg_categories,fg_sequence-content,fg_status" data-sd="db:'gene',op:'select',term:'',qk:'7163',linkname:'',idsfromresult:'10868',extra:''"><ul class="facet" data-filter_id="gene-sources" id="_gene-sources"><li class="filter_grp "><div class="clearfix"><h3>Gene sources</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="genomic">Genomic</a></li></ul></li></ul><ul class="facet" data-filter_id="categories" id="_categories"><li class="filter_grp "><div class="clearfix"><h3>Categories</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="alt-splicing">Alternatively spliced</a></li><li class="fil_val"><a href="#" data-value_id="annotated-genes">Annotated genes</a></li><li class="fil_val"><a href="#" data-value_id="gene-type-protein-coding">Protein-coding</a></li></ul></li></ul><ul class="facet" data-filter_id="sequence-content" id="_sequence-content"><li class="filter_grp "><div class="clearfix"><h3>Sequence content</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="seq-ccds">CCDS</a></li><li class="fil_val"><a href="#" data-value_id="seq-ensembl">Ensembl</a></li><li class="fil_val"><a href="#" data-value_id="refseq">RefSeq</a></li><li class="fil_val"><a href="#" data-value_id="seq-refseqgene">RefSeqGene</a></li></ul></li></ul><ul class="facet" data-filter_id="status" id="_status"><li class="filter_grp "><div class="clearfix"><h3>Status</h3><a href="#" data-value_id="" class="clear clear_show">Clear</a></div><ul><li class="fil_val selected"><a href="#" data-value_id="current-only">Current</a><span class="fcount">(1)</span></li></ul></li></ul><div id="chr-location-facet-wrapper" data-bid="MCID_67c9ffe7d74f67691048c2cd" data-hid="MCID_67c90f2d64f30b25346ccae2" data-qky="7163" class="disabled" style="display:none"><ul class="facet" data-filter_id="chromosomal-region" id="_chromosomal-region" data-of="yes"><li class="filter_grp of_grp"><div class="clearfix"><h3>Chromosome locations</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><a id="facet_ofchromosomal-region" href="#facet_of_divchromosomal-region" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'middle left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '375px'" data-value_id="fetch_more">more...</a><div id="facet_of_divchromosomal-region" style="display:none;" class="of_popup"><h4>Chromosome locations</h4><label for="organism-filter" style="width:100%;margin-bottom:.2em;" class="">Select an organism by typing or scrolling</label><input type="text" placeholder="Enter text to narrow down the list" id="organism-filter" style="width:98%;" autocomplete="off" /><br /><div id="chr-region-tax-list"><select id="of_chromosomal-region" size="9" class="chr-region-tax-list" style="width:100%;"></select></div><div id="chr-location-info-ctrl" data-disabled="disabled"><div class="chr-field"><label for="chr-name">Chromosome</label><br /><select id="chr-name" class="chr-field" disabled="disabled"></select></div><div class="chr-field"><label for="chr-from">From</label><br /><input type="text" name="chr-from" id="chr-from" disabled="disabled" class="chr-field" /></div><div class="chr-field"><label for="chr-to">To</label><br /><input type="text" name="chr-to" id="chr-to" disabled="disabled" class="chr-field" /></div></div><div class="actions clearfix"><button class="jig-ncbibutton of_add apply-chr" data-jigconfig="'color': 'ui-ncbibutton-blue'">Apply</button></div></div></ul></li></ul></div><ul class="facet facet_reset"><li><a href="#" data-value_id="reset">Clear all</a></li></ul><ul class="facet_tools"><li><a id="more_filter_groups_link" href="#more_filter_groups" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'top left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '180px'">
|
||
Show additional filters</a></li><div id="more_filter_groups" style="display:none;" class="facets_dialog"><button class="ui-ncbipopper-close-button ui-ncbipopper-close-button-generated ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-blue" generated="true" role="button" aria-disabled="false"><span class="ui-button-text">x</span></button><h4>Additional filters</h4><ul class="filter_groups_more facet"><li><input type="checkbox" id="fg_gene-sources" /><label for="fg_gene-sources">Gene sources</label></li><li><input type="checkbox" id="fg_categories" /><label for="fg_categories">Categories</label></li><li><input type="checkbox" id="fg_sequence-content" /><label for="fg_sequence-content">Sequence content</label></li><li><input type="checkbox" id="fg_status" /><label for="fg_status">Status</label></li><li><input type="checkbox" id="fg_chromosomal-region" /><label for="fg_chromosomal-region">Chromosome locations</label></li><li><input id="fg_field_search" type="checkbox" /><label for="fg_field_search">Search fields</label></li></ul><div class="actions clearfix"><button class="filter_groups_more_apply jig-ncbibutton primary-action" id="filter_groups_apply" data-jigconfig="'color': 'ui-ncbibutton-blue'">Show</button></div></div></ul><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetsUrlFrag" sid="1" type="hidden" value="filters=current-only" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetSubmitted" sid="1" type="hidden" value="false" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.BMFacets" sid="1" type="hidden" value="" /></div>
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<span style="display: block; text-align: center;">S</span>
|
||
<span style="display: block; text-align: center;">I</span>
|
||
<span style="display: block; text-align: center;">D</span>
|
||
<span style="display: block; text-align: center;">E</span>
|
||
<span style="display: block; text-align: center;">B</span>
|
||
<span style="display: block; text-align: center;">A</span>
|
||
<span style="display: block; text-align: center;">R</span>
|
||
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<div class="results_settings one_setting"><ul class="inline_list left display_settings"><li><a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Display" sid="0" href="#" class="jig-ncbipopper" data-jigconfig="triggerPosition : 'bottom center',destPosition : 'top center',destSelector : '#display_settings_menu_report', hasArrow : false,openEvent : 'click',closeEvent : 'click',isTriggerElementCloseClick: false,addCloseButton : false, groupName: 'entrez_pg'" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Display">Full Report<span href="#" class="tgt_dark"></span></a></li></ul><div id="display_settings_menu_report" class="disp_settings tabPopper"><fieldset class="format"><legend>Format</legend><ul class="column_list"><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="1" value="full_report" format="" id="full_report" checked="true" /><label for="full_report">Full Report</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="2" value="full_report" format="text" id="full_reporttext" /><label for="full_reporttext">Full Report (text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="3" value="expression" format="" id="expression" /><label for="expression">Expression</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="4" value="gene_table" format="" id="gene_table" /><label for="gene_table">Gene Table</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="5" value="gene_table" format="text" id="gene_tabletext" /><label for="gene_tabletext">Gene Table (text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="6" value="generif" format="" id="generif" /><label for="generif">GeneRIF</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="7" value="docsum" format="" id="docsum" /><label for="docsum">Summary</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="8" value="docsum" format="text" id="docsumtext" /><label for="docsumtext">Summary (text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="9" value="tabular" format="" id="tabular" /><label for="tabular">Tabular</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="10" value="tabular" format="text" id="tabulartext" /><label for="tabulartext">Tabular (text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="11" value="asn1" format="text" id="asn1text" /><label for="asn1text">ASN.1</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="12" value="xml" format="text" id="xmltext" /><label for="xmltext">XML</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="13" value="uilist" format="text" id="uilisttext" /><label for="uilisttext">UI List</label></li></ul></fieldset></div><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SetDisplay" sid="1" class="button_apply ncbipopper-close-button" style="display:none">Apply</button><h4 class="content_header send_to align_right jig-ncbipopper" id="sendto" data-jigconfig="triggerPosition:'bottom center', destPosition : 'top center',destSelector : '#send_to_menu', hasArrow : false, openEvent : 'click',closeEvent : 'click', isTriggerElementCloseClick: false, addCloseButton:true, groupName: 'entrez_pg', adjustFit:'none'"><a href="#" sourceContent="send_to_menu" class="tgt_dark">Send to:</a><script type="text/javascript">
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</script></h4><div id="send_to_menu" class="tabPopper send_to"><fieldset><legend>Choose Destination</legend><ul class="column_list"><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="1" value="File" id="dest_File" /><label for="dest_File">File</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="2" value="AddToClipboard" id="dest_AddToClipboard" /><label for="dest_AddToClipboard">Clipboard</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="3" value="AddToCollections" id="dest_AddToCollections" /><label for="dest_AddToCollections">Collections</label></li></ul></fieldset><div class="submenu file" id="submenu_File" style="display: none;"><p id="submenu_File_hint" class="hidden"></p><ul><li><label for="file_format">Format</label><select id="file_format" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FFormat" sid="1"><option value="full_report" format="text" selected="selected">Full Report (text)</option><option value="gene_table" format="text">Gene Table (text)</option><option value="docsum" format="text">Summary (text)</option><option value="tabular" format="text">Tabular (text)</option><option value="asn1" format="text">ASN.1</option><option value="xml" format="text">XML</option><option value="uilist" format="text">UI List</option></select></li></ul><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="1" class="button_apply file ncbipopper-close-button" type="submit" cmd="File">Create File</button></div><div class="submenu addtoclipboard" id="submenu_AddToClipboard" style="display: none;"><p id="submenu_AddToClipboard_hint" class="hidden"></p><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="2" class="button_apply clipboard ncbipopper-close-button" type="submit" cmd="AddToClipboard">Add to Clipboard</button></div><div class="submenu addtocollections" id="submenu_AddToCollections" style="display: none;"><p id="submenu_AddToCollections_hint" class="hidden"></p><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="3" class="button_apply collections ncbipopper-close-button" type="submit" cmd="AddToCollections">Add to Collections</button></div></div><div><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FileFormat" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastPresentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Presentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastPageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Sort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastSort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FileSort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Format" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastFormat" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevPageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevPresentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevSort" sid="1" type="hidden" value="" /><input type="hidden" id="coll_startindex" name="CollectionStartIndex" value="1" /></div></div>
|
||
<div>
|
||
|
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|
||
|
||
</div>
|
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<div class="">
|
||
<div><span id="result_sel" class="nowrap"></span><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_ResultsController.ResultCount" sid="1" type="hidden" id="resultcount" value="1" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_ResultsController.RunLastQuery" sid="1" type="hidden" /></div>
|
||
|
||
</div>
|
||
<div id="messagearea" class="empty">
|
||
|
||
|
||
|
||
|
||
</div>
|
||
<div class="rprt full-rprt">
|
||
<div>
|
||
<div class="rprt-header">
|
||
<input type="hidden" id="gene-tax-id" value="9606" />
|
||
<h1 class="title" id="gene-name"><span class="gn" style="padding-right:.5em;">USP20</span> ubiquitin specific peptidase 20 [ <em class="tax">Homo sapiens</em> (human)
|
||
]
|
||
</h1>
|
||
<span class="geneid">Gene ID: 10868, updated on
|
||
4-Mar-2025</span>
|
||
</div>
|
||
<div class="download-datasets">
|
||
<script type="text/javascript" src="https://cdnjs.cloudflare.com/ajax/libs/axios/0.23.0/axios.min.js"></script>
|
||
<h4 class="download-datasets-popper jig-ncbipopper" id="download-asm" style="align-self:start" data-jigconfig="triggerPosition:'bottom center', destPosition : 'top center',destSelector : '#download-datasets-popper-menu', hasArrow : false, openEvent : 'click',closeEvent : 'click', isTriggerElementCloseClick: false, groupName: 'entrez_pg', adjustFit:'none'" role="button" aria-expanded="false" aria-haspopup="true">
|
||
<svg alt="download" class="dlbtn-icon" x="0px" y="0px" width="15px" height="15px" viewBox="0 0 60 60" enable-background="new 0 0 60 60" xml:space="preserve">
|
||
<g>
|
||
<polygon points="48.75,36.25 48.75,48.75 11.25,48.75 11.25,36.25 5,36.25 5,55 55,55 55,36.25 "></polygon>
|
||
<polygon points="42.5,23.75 36.25,23.75 36.25,5 23.75,5 23.75,23.75 17.5,23.75 30,42.5 "></polygon>
|
||
</g>
|
||
</svg>
|
||
<a href="#">Download Datasets</a>
|
||
</h4>
|
||
<div id="download-datasets-popper-menu" style="display:none;">
|
||
<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-gene-seq-fasta" value="FASTA_GENE" checked="checked" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-gene-seq-fasta">Gene Sequences (FASTA)</label>
|
||
</div>
|
||
<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-transcript-seq-fasta" value="FASTA_RNA" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-transcript-seq-fasta">Transcript sequences (FASTA)</label>
|
||
</div>
|
||
<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-protein-seq-fasta" value="FASTA_PROTEIN" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-protein-seq-fasta">Protein sequences(FASTA)</label>
|
||
</div>
|
||
<p style="margin-left:5px;">In addition, your package will include a detailed data report in both TSV and JSONL formats.</p>
|
||
<div class="input-group">
|
||
<label for="datasets-download-file-name">File name</label>
|
||
<input type="text" id="datasets-download-file-name" placeholder="Name your file" style="padding:5px;" value="USP20_datasets.zip" />
|
||
</div>
|
||
<input type="hidden" id="download-datasets-base-url" value="https://api.ncbi.nlm.nih.gov/datasets/v2alpha/gene/download" />
|
||
<input type="hidden" id="gene-id-value" value="10868" />
|
||
<button id="datasets-download-submit" data-ga-action="click_begin_download" data-ga-label="download" class="jig-ncbibutton ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-gray" role="button">
|
||
<span class="ui-button-text">Download</span>
|
||
</button>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-body">
|
||
|
||
|
||
<div class="rprt-section gene-summary">
|
||
<section class="rprt-section-header" id="summary">
|
||
<h2 id="header-summary">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-summary .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Summary</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Summary_2" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div id="summaryDiv" class="section">
|
||
<dl id="summaryDl">
|
||
<dt class="noline"> Official
|
||
Symbol</dt>
|
||
<dd class="noline">USP20<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
|
||
<dt> Official
|
||
Full Name</dt>
|
||
<dd>ubiquitin specific peptidase 20<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
|
||
<dt>Primary source</dt>
|
||
<dd>
|
||
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:12619" data-gblink-text="Ensembl">HGNC:HGNC:12619</a>
|
||
</dd>
|
||
<dt>See related</dt>
|
||
<dd>
|
||
<a href="http://www.ensembl.org/id/ENSG00000136878" data-gblink-text="Ensembl" class="genome-browser-link" data-genome-browser-link-sort="5" data-gb-url="http://www.ensembl.org/loc/ENSG00000136878">Ensembl:ENSG00000136878</a>
|
||
<a href="https://www.ncbi.nlm.nih.gov/omim/615143" data-gblink-text="Ensembl" ref="ordinalpos=1&ncbi_uid=10868&link_uid=615143">MIM:615143;</a>
|
||
<a href="https://www.alliancegenome.org/gene/HGNC:12619" data-gblink-text="Ensembl" ref="ordinalpos=1&ncbi_uid=10868&link_uid=HGNC:12619">AllianceGenome:HGNC:12619</a>
|
||
</dd>
|
||
<dt>Gene type</dt>
|
||
<dd>protein coding</dd>
|
||
<dt>RefSeq status</dt>
|
||
<dd>REVIEWED</dd>
|
||
<dt>Organism</dt>
|
||
<dd class="tax">
|
||
<a href="/Taxonomy/Browser/wwwtax.cgi?id=9606" ref="ordinalpos=1&ncbi_uid=10868&link_uid=9606">Homo sapiens</a>
|
||
</dd>
|
||
<dt>Lineage</dt>
|
||
<dd class="tax">Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo</dd>
|
||
<dt>Also known as</dt>
|
||
<dd>VDU2; hVDU2; LSFR3A</dd>
|
||
<dt>Summary</dt>
|
||
<dd>This gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel-Lindau disease) protein E3 ubiquitin ligase complex. In addition to being ubiquitinated by the VHL-E3 ligase complex, this enzyme deubiquitinates hypoxia-inducible factor (HIF)-1 alpha and thereby causes increased expression of HIF-1alpha targeted genes which play a role in angiogenesis, glucose metabolism, cell proliferation and metastasis. The enzyme encoded by this gene also regulates G-protein coupled receptor signaling by mediating the deubiquitination of beta-2 adrenergic receptor (ADRB2). This enzyme is a ubiquitously expressed thiolester hydrolase. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jan 2013]</dd>
|
||
<dt>Expression</dt>
|
||
<dd>Ubiquitous expression in lymph node (RPKM 8.9), bone marrow (RPKM 8.3) and 25 other tissues <a href="#gene-expression">See more</a></dd>
|
||
<dt>Orthologs</dt>
|
||
<dd class="ortholog-links">
|
||
<a href="https://www.ncbi.nlm.nih.gov/gene/74270">mouse</a>
|
||
<a href="/gene/10868/ortholog/">all</a>
|
||
</dd>
|
||
<dt style="padding-top:.5em;">
|
||
<span class="new-icon">NEW</span>
|
||
</dt>
|
||
<dd style="padding-top:.5em;">
|
||
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/10868/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="gene_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Gene table</a></strong>
|
||
<br />
|
||
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/10868/products/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="transcript_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Transcript table</a></strong>
|
||
</dd>
|
||
</dl>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-genomic-context">
|
||
<section class="rprt-section-header" id="genomic-context">
|
||
<h2 id="header-genomic-context">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-context .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Genomic context</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Genomic_Context" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div class="gc_cont">
|
||
<div class="gt_cont_contents">
|
||
<div style="float:right"><span>See USP20 in </span><a href="/genome/gdv/?context=gene&acc=10868" class="link-to-gdv genome-browser-link" data-genome-browser-link-sort="1" data-acc="GCF_000001405.40">Genome Data Viewer</a> </div>
|
||
<dl class="dl-chr-info" style="float:left;margin-top:0;">
|
||
<dt>Location: </dt>
|
||
<dd>
|
||
<span style="display:inline-block;">9q34.11</span>
|
||
</dd>
|
||
</dl>
|
||
</div>
|
||
<dl class="dl-chr-info exon-count">
|
||
<dt>Exon count: </dt>
|
||
<dd>26</dd>
|
||
</dl>
|
||
<div class="ui-ncbigrid-outer-div" id="genomic-context-tbl-location">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="">
|
||
<thead>
|
||
<tr>
|
||
<th style="max-width:15%">Annotation release</th>
|
||
<th style="max-width:10%">Status</th>
|
||
<th>Assembly</th>
|
||
<th>
|
||
<span title="Chromosome">Chr</span>
|
||
</th>
|
||
<th>Location</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td>RS_2024_08</td>
|
||
<td>current</td>
|
||
<td>GRCh38.p14 (<a href="/assembly/GCF_000001405.40/" ref="ncbi_uid=10868&link_uid=GCF_000001405.40">GCF_000001405.40</a>)</td>
|
||
<td>9</td>
|
||
<td>NC_000009.12 (129835458..129881828) </td>
|
||
</tr>
|
||
<tr>
|
||
<td>RS_2024_08</td>
|
||
<td>current</td>
|
||
<td>T2T-CHM13v2.0 (<a href="/assembly/GCF_009914755.1/" ref="ncbi_uid=10868&link_uid=GCF_009914755.1">GCF_009914755.1</a>)</td>
|
||
<td>9</td>
|
||
<td>NC_060933.1 (142040029..142086556) </td>
|
||
</tr>
|
||
<tr>
|
||
<td>RS_2024_09</td>
|
||
<td>previous assembly</td>
|
||
<td>GRCh37.p13 (<a href="/assembly/GCF_000001405.25/" ref="ncbi_uid=10868&link_uid=GCF_000001405.25">GCF_000001405.25</a>)</td>
|
||
<td>9</td>
|
||
<td>NC_000009.11 (132597737..132644107) </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<p class="withnote margin_t2em"><strong>Chromosome 9 - NC_000009.12</strong><img usemap="#nbrMap10868_568815589" border="0" alt="Genomic Context describing neighboring genes" src="/gutils/geneneighb.fcgi?geneid=10868&nuc_gi=568815589&n0=TOR1A&n1=LOC130002771&n2=LOC130002772&n3=C9orf78&n4=LOC124310662&n5=LOC130002773&n6=USP20&n7=LOC127816272&n8=LOC127816273&n9=LOC130002774&n10=LOC124310663&n11=MIR6855&n12=LOC127816274&n13=LOC127816275&n14=LOC113839529&n15=LOC127816276&n16=LOC130002775&n17=LOC130002776&n18=FNBP1&n19=LOC130002777&n20=LOC127816277&n21=LOC124310664&n22=LOC130002778&n23=LOC124310665&n24=LOC130002779&n25=LOC130002780&n26=LOC130002781&n27=LOC130002782&n28=LOC130002783&n29=LOC130002784&n30=LOC124310666&n31=LOC130002785&n32=LOC130002786&n33=LOC130002787&n34=LOC130002788&n35=LOC130002789&n36=LOC130002790&n37=LOC130002791&n38=LOC130002792&n39=LOC130002793&n40=LOC130002794&n41=LOC130002795&n42=LOC129662555&n43=LOC130002796&n44=LOC130002797&n45=LOC127816278&n46=LOC127816279&n47=LOC130002798&n48=LOC130002799&n49=LOC130002800&n50=LOC130002801&n51=LOC127816280&n52=LOC130002802&n53=GPR107&n54=LOC127816281&n55=LOC127816282&n56=LOC130002803&n57=LOC130002804" /><map name="nbrMap10868_568815589" id="nbrMap10868_568815589">
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 20390')" onMouseOut="hidetip()" coords="14,23,84,31" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20390" href="/gene/130002771" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29122')" onMouseOut="hidetip()" coords="14,35,84,43" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29122" href="/gene/130002772" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 5710')" onMouseOut="hidetip()" coords="19,47,89,55" alt="Neighboring gene Sharpr-MPRA regulatory region 5710" href="/gene/124310662" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 20391')" onMouseOut="hidetip()" coords="26,59,96,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20391" href="/gene/130002773" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac hESC enhancer GRCh37_chr9:132597987-132598487')" onMouseOut="hidetip()" coords="27,71,97,79" alt="Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:132597987-132598487" href="/gene/127816272" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr9:132601680-132602180')" onMouseOut="hidetip()" coords="31,83,101,91" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:132601680-132602180" href="/gene/127816273" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'torsin family 1 member A')" onMouseOut="hidetip()" coords="37,95,76,103" alt="Neighboring gene torsin family 1 member A" href="/gene/1861" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'chromosome 9 open reading frame 78')" onMouseOut="hidetip()" coords="43,107,89,115" alt="Neighboring gene chromosome 9 open reading frame 78" href="/gene/51759" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29123')" onMouseOut="hidetip()" coords="57,119,127,127" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29123" href="/gene/130002774" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 12255')" onMouseOut="hidetip()" coords="59,131,129,139" alt="Neighboring gene Sharpr-MPRA regulatory region 12255" href="/gene/124310663" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr9:132632499-132632998')" onMouseOut="hidetip()" coords="65,155,135,163" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:132632499-132632998" href="/gene/127816274" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac hESC enhancer GRCh37_chr9:132636644-132637144')" onMouseOut="hidetip()" coords="69,167,139,175" alt="Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:132636644-132637144" href="/gene/127816275" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 12063')" onMouseOut="hidetip()" coords="80,95,150,103" alt="Neighboring gene Sharpr-MPRA regulatory region 12063" href="/gene/113839529" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:132647083-132647764')" onMouseOut="hidetip()" coords="81,179,151,187" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:132647083-132647764" href="/gene/127816276" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29125')" onMouseOut="hidetip()" coords="82,191,152,199" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29125" href="/gene/130002775" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 20393')" onMouseOut="hidetip()" coords="82,203,152,211" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20393" href="/gene/130002776" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29126')" onMouseOut="hidetip()" coords="85,23,155,31" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29126" href="/gene/130002777" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:132651249-132652136')" onMouseOut="hidetip()" coords="85,35,155,43" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:132651249-132652136" href="/gene/127816277" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'microRNA 6855')" onMouseOut="hidetip()" coords="89,215,134,223" alt="Neighboring gene microRNA 6855" href="/gene/102466750" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 3297')" onMouseOut="hidetip()" coords="90,47,160,55" alt="Neighboring gene Sharpr-MPRA regulatory region 3297" href="/gene/124310664" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29128')" onMouseOut="hidetip()" coords="98,59,168,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29128" href="/gene/130002778" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 1290')" onMouseOut="hidetip()" coords="109,71,179,79" alt="Neighboring gene Sharpr-MPRA regulatory region 1290" href="/gene/124310665" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'formin binding protein 1')" onMouseOut="hidetip()" coords="118,83,328,91" alt="Neighboring gene formin binding protein 1" href="/gene/23048" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29129')" onMouseOut="hidetip()" coords="133,107,203,115" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29129" href="/gene/130002779" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29130')" onMouseOut="hidetip()" coords="134,119,204,127" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29130" href="/gene/130002780" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29131')" onMouseOut="hidetip()" coords="134,131,204,139" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29131" href="/gene/130002781" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29132')" onMouseOut="hidetip()" coords="134,227,204,235" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29132" href="/gene/130002782" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 20394')" onMouseOut="hidetip()" coords="147,143,217,151" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20394" href="/gene/130002783" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29133')" onMouseOut="hidetip()" coords="195,23,265,31" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29133" href="/gene/130002784" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 9235')" onMouseOut="hidetip()" coords="196,35,266,43" alt="Neighboring gene Sharpr-MPRA regulatory region 9235" href="/gene/124310666" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29134')" onMouseOut="hidetip()" coords="199,47,269,55" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29134" href="/gene/130002785" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29135')" onMouseOut="hidetip()" coords="199,59,269,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29135" href="/gene/130002786" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29136')" onMouseOut="hidetip()" coords="202,71,272,79" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29136" href="/gene/130002787" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29137')" onMouseOut="hidetip()" coords="203,95,273,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29137" href="/gene/130002788" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29138')" onMouseOut="hidetip()" coords="203,155,273,163" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29138" href="/gene/130002789" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29139')" onMouseOut="hidetip()" coords="203,167,273,175" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29139" href="/gene/130002790" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29140')" onMouseOut="hidetip()" coords="216,107,286,115" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29140" href="/gene/130002791" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29141')" onMouseOut="hidetip()" coords="216,119,286,127" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29141" href="/gene/130002792" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29142')" onMouseOut="hidetip()" coords="218,131,288,139" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29142" href="/gene/130002793" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29143')" onMouseOut="hidetip()" coords="219,143,289,151" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29143" href="/gene/130002794" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29144')" onMouseOut="hidetip()" coords="232,179,302,187" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29144" href="/gene/130002795" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ReSE screen-validated silencer GRCh37_chr9:132786300-132786450')" onMouseOut="hidetip()" coords="234,191,304,199" alt="Neighboring gene ReSE screen-validated silencer GRCh37_chr9:132786300-132786450" href="/gene/129662555" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29145')" onMouseOut="hidetip()" coords="238,203,308,211" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29145" href="/gene/130002796" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29146')" onMouseOut="hidetip()" coords="239,215,309,223" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29146" href="/gene/130002797" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac hESC enhancer GRCh37_chr9:132796970-132797470')" onMouseOut="hidetip()" coords="245,227,315,235" alt="Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:132796970-132797470" href="/gene/127816278" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac hESC enhancer GRCh37_chr9:132797471-132797971')" onMouseOut="hidetip()" coords="246,239,316,247" alt="Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:132797471-132797971" href="/gene/127816279" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29148')" onMouseOut="hidetip()" coords="250,251,320,259" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29148" href="/gene/130002798" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 20395')" onMouseOut="hidetip()" coords="252,263,322,271" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20395" href="/gene/130002799" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 20396')" onMouseOut="hidetip()" coords="254,275,324,283" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20396" href="/gene/130002800" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 20397')" onMouseOut="hidetip()" coords="254,287,324,295" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20397" href="/gene/130002801" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr9:132811133-132811633')" onMouseOut="hidetip()" coords="261,299,331,307" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:132811133-132811633" href="/gene/127816280" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 20398')" onMouseOut="hidetip()" coords="266,23,336,31" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20398" href="/gene/130002802" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'G protein-coupled receptor 107')" onMouseOut="hidetip()" coords="296,35,423,43" alt="Neighboring gene G protein-coupled receptor 107" href="/gene/57720" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:132878169-132878714')" onMouseOut="hidetip()" coords="334,47,404,55" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:132878169-132878714" href="/gene/127816281" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:132881191-132882139')" onMouseOut="hidetip()" coords="338,23,408,31" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr9:132881191-132882139" href="/gene/127816282" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 20399')" onMouseOut="hidetip()" coords="342,59,412,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20399" href="/gene/130002803" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 29149')" onMouseOut="hidetip()" coords="349,71,419,79" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29149" href="/gene/130002804" />
|
||
</map>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-genomic-regions-transcripts-products">
|
||
<section class="rprt-section-header" id="genomic-regions-transcripts-products">
|
||
<h2 id="header-genomic-regions-transcripts-products">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-regions-transcripts-products .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Genomic regions, transcripts, and products</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Genomic_Regions_Transcripts_a" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<div style="text-align:right;">Go to <a href="#reference-sequences">reference sequence details</a></div>
|
||
</div>
|
||
<div>
|
||
<p class="choose">
|
||
<label for="accession" class="label">Genomic Sequence: </label>
|
||
<select name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.accessionList" sid="1" id="accessionList" data-taxid="9606" data-geneid="10868">
|
||
<option value="NC_000009.12_129835457_129881827">NC_000009.12 Chromosome 9 Reference GRCh38.p14 Primary Assembly</option>
|
||
<option value="NG_033097.2_5029_51399">NG_033097.2 RefSeqGene</option>
|
||
<option value="NC_060933.1_142040028_142086555">NC_060933.1 Chromosome 9 Alternate T2T-CHM13v2.0</option>
|
||
<option value="NC_000009.11_132597736_132644106">NC_000009.11 Chromosome 9 Reference GRCh37.p13 Primary Assembly</option>
|
||
</select>
|
||
</p>
|
||
</div>
|
||
<div id="NC_000009" class="divAccession">
|
||
<div class="seq-viewer">
|
||
<p class="note-link">
|
||
<strong>Go to nucleotide:</strong>
|
||
<a title="Nucleotide Graphic report" href="/nuccore/NC_000009.12?report=graph&from=129828501&to=129888783&app_context=Gene&assm_context=GCF_000001405.40" ref="ordinalpos=1&ncbi_uid=10868&link_uid=NC_000009.12">Graphics</a>
|
||
<a title="Nucleotide FASTA report" href="/nuccore/NC_000009.12?report=fasta&from=129835458&to=129881828" ref="ordinalpos=1&ncbi_uid=10868&link_uid=NC_000009.12">FASTA</a>
|
||
<a title="Nucleotide GenBank report" href="/nuccore/NC_000009.12?report=genbank&from=129835458&to=129881828" ref="ordinalpos=1&ncbi_uid=10868&link_uid=NC_000009.12">GenBank</a>
|
||
</p>
|
||
<div id="divNC_000009" class="SeqViewerApp" style="clear:both;" data-sv="appname=ncbigene&embedded=true&noslider=1&id=NC_000009.12&from=129828501&to=129888783&app_context=Gene&assm_context=GCF_000001405.40">
|
||
<a href="?appname=ncbigene&embedded=true&noslider=1&id=NC_000009.12&from=129828501&to=129888783&app_context=Gene&assm_context=GCF_000001405.40"></a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000009.12" sid="1" type="hidden" id="nucleotideLink_NC_000009_12_129835457_129881827" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_000009.12?report=graph&amp;from=129828501&amp;to=129888783&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" ref="ordinalpos=1&amp;ncbi_uid=10868&amp;link_uid=NC_000009.12">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_000009.12?report=fasta&amp;from=129835458&amp;to=129881828" ref="ordinalpos=1&amp;ncbi_uid=10868&amp;link_uid=NC_000009.12">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_000009.12?report=genbank&amp;from=129835458&amp;to=129881828" ref="ordinalpos=1&amp;ncbi_uid=10868&amp;link_uid=NC_000009.12">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000009.12" sid="1" type="hidden" id="relString_NC_000009_12_129835457_129881827" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000009.12&amp;from=129828501&amp;to=129888783&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NG_033097.2" sid="1" type="hidden" id="nucleotideLink_NG_033097_2_5029_51399" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NG_033097.2?report=graph&amp;from=1&amp;to=58355&amp;tracks=[key:sequence_track,name:Sequence,display_name:Sequence,category:Sequence,annots:Sequence,ShowLabel:false][key:gene_model_track,name:Genes---Unnamed,display_name:Genes,annots:Unnamed,Options:ShowAllButGenes,SNPs:false,CDSProductFeats:false,ShowLabelsForAllFeatures:true,HighlightMode:2][key:SNP_track,name:SNP,annots:SNP,Layout:Adaptive][key:SNP_Bins_track,name:Clinical Variants][key:SNP_Bins_track,name:Cited Variants][key:GWAS_track,name:GWAS Tracks,display_name:Association Results][key:alignment_track,category:Alignments,annots:Unnamed][key:alignment_track,category:Alignments,annots:NA000079160.1][key:alignment_track,category:Alignments,annots:NA000010065.1]" ref="ordinalpos=1&amp;ncbi_uid=10868&amp;link_uid=NG_033097.2">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NG_033097.2?report=fasta&amp;from=5030&amp;to=51400" ref="ordinalpos=1&amp;ncbi_uid=10868&amp;link_uid=NG_033097.2">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NG_033097.2?report=genbank&amp;from=5030&amp;to=51400" ref="ordinalpos=1&amp;ncbi_uid=10868&amp;link_uid=NG_033097.2">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NG_033097.2" sid="1" type="hidden" id="relString_NG_033097_2_5029_51399" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NG_033097.2&amp;from=1&amp;to=58355&amp;tracks=[key:sequence_track,name:Sequence,display_name:Sequence,category:Sequence,annots:Sequence,ShowLabel:false][key:gene_model_track,name:Genes---Unnamed,display_name:Genes,annots:Unnamed,Options:ShowAllButGenes,SNPs:false,CDSProductFeats:false,ShowLabelsForAllFeatures:true,HighlightMode:2][key:SNP_track,name:SNP,annots:SNP,Layout:Adaptive][key:SNP_Bins_track,name:Clinical Variants][key:SNP_Bins_track,name:Cited Variants][key:GWAS_track,name:GWAS Tracks,display_name:Association Results][key:alignment_track,category:Alignments,annots:Unnamed][key:alignment_track,category:Alignments,annots:NA000079160.1][key:alignment_track,category:Alignments,annots:NA000010065.1]" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_060933.1" sid="1" type="hidden" id="nucleotideLink_NC_060933_1_142040028_142086555" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_060933.1?report=graph&amp;from=142033049&amp;to=142093534&amp;app_context=Gene&amp;assm_context=GCF_009914755.1" ref="ordinalpos=1&amp;ncbi_uid=10868&amp;link_uid=NC_060933.1">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_060933.1?report=fasta&amp;from=142040029&amp;to=142086556" ref="ordinalpos=1&amp;ncbi_uid=10868&amp;link_uid=NC_060933.1">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_060933.1?report=genbank&amp;from=142040029&amp;to=142086556" ref="ordinalpos=1&amp;ncbi_uid=10868&amp;link_uid=NC_060933.1">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_060933.1" sid="1" type="hidden" id="relString_NC_060933_1_142040028_142086555" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_060933.1&amp;from=142033049&amp;to=142093534&amp;app_context=Gene&amp;assm_context=GCF_009914755.1" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000009.11" sid="1" type="hidden" id="nucleotideLink_NC_000009_11_132597736_132644106" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_000009.11?report=graph&amp;from=132590780&amp;to=132651062&amp;app_context=Gene&amp;assm_context=GCF_000001405.25" ref="ordinalpos=1&amp;ncbi_uid=10868&amp;link_uid=NC_000009.11">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_000009.11?report=fasta&amp;from=132597737&amp;to=132644107" ref="ordinalpos=1&amp;ncbi_uid=10868&amp;link_uid=NC_000009.11">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_000009.11?report=genbank&amp;from=132597737&amp;to=132644107" ref="ordinalpos=1&amp;ncbi_uid=10868&amp;link_uid=NC_000009.11">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000009.11" sid="1" type="hidden" id="relString_NC_000009_11_132597736_132644106" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000009.11&amp;from=132590780&amp;to=132651062&amp;app_context=Gene&amp;assm_context=GCF_000001405.25" />
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-gene-expression">
|
||
<section class="rprt-section-header" id="gene-expression">
|
||
<h2 id="header-gene-expression">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-gene-expression .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Expression</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Expression" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<div style="text-align:right;">
|
||
<a href="/gene/10868/?report=expression" data-url="/gene/10868/?report=expression" id="gene-expression-see-details">See details</a>
|
||
</div>
|
||
<div id="gene-expression-app" data-url="https://www.ncbi.nlm.nih.gov/gene/10868" data-report-type="summary">
|
||
<div>
|
||
<script type="text/javascript">
|
||
|
||
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'heart 10wk', 'full_rpkm': 0.653775, 'exp_rpkm': 0.654, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416130113545}, 'heart 11wk': {'id': '10868_Heart_11wk;_PRJNA270632', 'gene': 10868, 'source_name': 'heart 11wk', 'full_rpkm': 0.639009, 'exp_rpkm': 0.639, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416130113546}, 'heart 17wk': {'id': '10868_Heart_17wk;_PRJNA270632', 'gene': 10868, 'source_name': 'heart 17wk', 'full_rpkm': 0.457197, 'exp_rpkm': 0.457, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416130113547}, 'heart 18wk': {'id': '10868_Heart_18wk;_PRJNA270632', 'gene': 10868, 'source_name': 'heart 18wk', 'full_rpkm': 0.614552, 'exp_rpkm': 0.615, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416130113548}, 'heart 20wk': {'id': '10868_Heart_20wk_PRJNA270632', 'gene': 10868, 'source_name': 'heart 20wk', 'full_rpkm': 0.105707, 'exp_rpkm': 0.106, 'var': 0.00338952, 'project_desc': 'PRJNA270632', '_version_': 1785734416130113549}, 'intestine 10wk': {'id': '10868_Intestine_10wk_PRJNA270632', 'gene': 10868, 'source_name': 'intestine 10wk', 'full_rpkm': 0.101757, 'exp_rpkm': 0.102, 'var': 3.47224e-05, 'project_desc': 'PRJNA270632', '_version_': 1785734416130113550}, 'intestine 11wk': {'id': '10868_Intestine_11wk_PRJNA270632', 'gene': 10868, 'source_name': 'intestine 11wk', 'full_rpkm': 0.29373, 'exp_rpkm': 0.294, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416130113551}, 'intestine 15wk': {'id': '10868_Intestine_15wk_PRJNA270632', 'gene': 10868, 'source_name': 'intestine 15wk', 'full_rpkm': 0.569559, 'exp_rpkm': 0.57, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416130113552}, 'intestine 17wk': {'id': '10868_Intestine_17wk_PRJNA270632', 'gene': 10868, 'source_name': 'intestine 17wk', 'full_rpkm': 0.382626, 'exp_rpkm': 0.383, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416130113553}, 'intestine 20wk': {'id': 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{'id': '10868_Stomach_18wk_PRJNA270632', 'gene': 10868, 'source_name': 'stomach 18wk', 'full_rpkm': 1.11582, 'exp_rpkm': 1.12, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734416130113563}, 'stomach 20wk': {'id': '10868_Stomach_20wk_PRJNA270632', 'gene': 10868, 'source_name': 'stomach 20wk', 'full_rpkm': 0.977359, 'exp_rpkm': 0.977, 'var': 0.002232015, 'project_desc': 'PRJNA270632', '_version_': 1785734416130113564}};
|
||
|
||
|
||
|
||
|
||
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"metadata_9606_SAMN03267775", "gene": 10868, "sample_id": "SAMN03267775", "full_rpkm": 0.569559, "exp_rpkm": 0.57, "exp_total": 12460, "project_desc": "PRJNA270632", "_version_": 1785734387344605201, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 15wk", "exp_Mcount": 3980.45}], "intestine 17wk": [{"id": "metadata_9606_SAMN03267782", "gene": 10868, "sample_id": "SAMN03267782", "full_rpkm": 0.382626, "exp_rpkm": 0.383, "exp_total": 20326, "project_desc": "PRJNA270632", "_version_": 1785734387344605200, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 17wk", "exp_Mcount": 9665.65}], "intestine 20wk": [{"id": "metadata_9606_SAMN03267766", "gene": 10868, "sample_id": "SAMN03267766", "full_rpkm": 0.325969, "exp_rpkm": 0.326, "exp_total": 7455, "project_desc": "PRJNA270632", "_version_": 1785734387344605198, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 20wk", "exp_Mcount": 4161.26}, {"id": "metadata_9606_SAMN03267769", "gene": 10868, "sample_id": "SAMN03267769", "full_rpkm": 0.644395, "exp_rpkm": 0.644, "exp_total": 13791, "project_desc": "PRJNA270632", "_version_": 1785734387344605199, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "intestine 20wk", "exp_Mcount": 3894.01}], "kidney 10wk": [{"id": "metadata_9606_SAMN03267784", "gene": 10868, "sample_id": "SAMN03267784", "full_rpkm": 0.424884, "exp_rpkm": 0.425, "exp_total": 11035, "project_desc": "PRJNA270632", "_version_": 1785734387344605197, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "kidney 10wk", "exp_Mcount": 4725.59}], "kidney 16wk": [{"id": "metadata_9606_SAMN03267772", "gene": 10868, "sample_id": "SAMN03267772", "full_rpkm": 0.296344, "exp_rpkm": 0.296, "exp_total": 24900, "project_desc": "PRJNA270632", "_version_": 1785734387344605196, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "kidney 16wk", "exp_Mcount": 15288.2}], "kidney 20wk": [{"id": "metadata_9606_SAMN03267777", "gene": 10868, "sample_id": "SAMN03267777", "full_rpkm": 0.134869, "exp_rpkm": 0.135, "exp_total": 7620, "project_desc": "PRJNA270632", "_version_": 1785734387344605195, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "kidney 20wk", "exp_Mcount": 10280.0}], "lung 10wk": [{"id": "metadata_9606_SAMN03267770", "gene": 10868, "sample_id": "SAMN03267770", "full_rpkm": 0.775913, "exp_rpkm": 0.776, "exp_total": 25385, "project_desc": "PRJNA270632", "_version_": 1785734387344605193, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 10wk", "exp_Mcount": 5952.75}, {"id": "metadata_9606_SAMN03267767", "gene": 10868, "sample_id": "SAMN03267767", "full_rpkm": 0.907029, "exp_rpkm": 0.907, "exp_total": 26078, "project_desc": "PRJNA270632", "_version_": 1785734387344605194, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 10wk", "exp_Mcount": 5231.26}], "lung 17wk": [{"id": "metadata_9606_SAMN03267778", "gene": 10868, "sample_id": "SAMN03267778", "full_rpkm": 0.760184, "exp_rpkm": 0.76, "exp_total": 26130, "project_desc": "PRJNA270632", "_version_": 1785734387344605191, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 17wk", "exp_Mcount": 6254.23}, {"id": "metadata_9606_SAMN03267776", "gene": 10868, "sample_id": "SAMN03267776", "full_rpkm": 0.877835, "exp_rpkm": 0.878, "exp_total": 18060, "project_desc": "PRJNA270632", "_version_": 1785734387344605192, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 17wk", "exp_Mcount": 3743.33}], "lung 20wk": [{"id": "metadata_9606_SAMN03267780", "gene": 10868, "sample_id": "SAMN03267780", "full_rpkm": 0.786204, "exp_rpkm": 0.786, "exp_total": 40056, "project_desc": "PRJNA270632", "_version_": 1785734387344605189, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 20wk", "exp_Mcount": 9270.13}, {"id": "metadata_9606_SAMN03267768", "gene": 10868, "sample_id": "SAMN03267768", "full_rpkm": 0.761079, "exp_rpkm": 0.761, "exp_total": 26572, "project_desc": "PRJNA270632", "_version_": 1785734387344605190, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 20wk", "exp_Mcount": 6352.54}], "stomach 10wk": [{"id": "metadata_9606_SAMN03267773", "gene": 10868, "sample_id": "SAMN03267773", "full_rpkm": 0.563791, "exp_rpkm": 0.564, "exp_total": 20395, "project_desc": "PRJNA270632", "_version_": 1785734387344605187, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 10wk", "exp_Mcount": 6582.02}, {"id": "metadata_9606_SAMN03267779", "gene": 10868, "sample_id": "SAMN03267779", "full_rpkm": 1.05624, "exp_rpkm": 1.06, "exp_total": 41994, "project_desc": "PRJNA270632", "_version_": 1785734387344605188, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 10wk", "exp_Mcount": 7234.02}], "stomach 16wk": [{"id": "metadata_9606_SAMN03267774", "gene": 10868, "sample_id": "SAMN03267774", "full_rpkm": 0.895852, "exp_rpkm": 0.896, "exp_total": 30622, "project_desc": "PRJNA270632", "_version_": 1785734387344605186, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 16wk", "exp_Mcount": 6219.43}], "stomach 18wk": [{"id": "metadata_9606_SAMN03267771", "gene": 10868, "sample_id": "SAMN03267771", "full_rpkm": 1.11582, "exp_rpkm": 1.12, "exp_total": 35694, "project_desc": "PRJNA270632", "_version_": 1785734387344605185, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 18wk", "exp_Mcount": 5820.42}], "stomach 20wk": [{"id": "metadata_9606_SAMN03267765", "gene": 10868, "sample_id": "SAMN03267765", "full_rpkm": 1.03213, "exp_rpkm": 1.03, "exp_total": 25496, "project_desc": "PRJNA270632", "_version_": 1785734387342508032, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4494.58}, {"id": "metadata_9606_SAMN03267781", "gene": 10868, "sample_id": "SAMN03267781", "full_rpkm": 0.983104, "exp_rpkm": 0.983, "exp_total": 24672, "project_desc": "PRJNA270632", "_version_": 1785734387343556608, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4566.24}, {"id": "metadata_9606_SAMN03267783", "gene": 10868, "sample_id": "SAMN03267783", "full_rpkm": 0.916839, "exp_rpkm": 0.917, "exp_total": 24210, "project_desc": "PRJNA270632", "_version_": 1785734387344605184, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4804.58}]}
|
||
window.taxId = 9606
|
||
</script>
|
||
|
||
|
||
<div>
|
||
|
||
|
||
|
||
<select name="p" id="project-selector">
|
||
|
||
|
||
<option value="SRP051249" selected="selected" data-bioproject="PRJNA270632">
|
||
|
||
Tissue-specific circular RNA induction during human fetal development
|
||
|
||
</option>
|
||
|
||
|
||
|
||
<option value="SRP056969" data-bioproject="PRJNA280600">
|
||
|
||
RNA sequencing of total RNA from 20 human tissues
|
||
|
||
|
||
</option>
|
||
|
||
|
||
|
||
<option value="ERP003613" data-bioproject="PRJEB4337">
|
||
|
||
HPA RNA-seq normal tissues
|
||
|
||
|
||
</option>
|
||
|
||
|
||
|
||
</select>
|
||
|
||
|
||
|
||
<ul id="project-summary">
|
||
<li id="project-summary-title">Project title:
|
||
|
||
Tissue-specific circular RNA induction during human fetal development
|
||
|
||
</li>
|
||
|
||
|
||
<li id="project-summary-desc">Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA</li>
|
||
|
||
|
||
|
||
<li id="project-summary-bioprojects">BioProject: <a href="/bioproject/PRJNA270632/">PRJNA270632</a>
|
||
</li>
|
||
|
||
<li id="project-summary-pubs">Publication:
|
||
|
||
|
||
<span><a href="/pubmed/26076956/">PMID 26076956</a></span>
|
||
|
||
</li>
|
||
|
||
|
||
<li id="project-summary-analysis-date">Analysis date: Mon Apr 2 22:54:59 2018</li>
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
<div id="gene-expr-details" class="expression-chart"></div>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<script type="text/javascript" src="https://www.gstatic.com/charts/loader.js"></script>
|
||
<script type="text/javascript">
|
||
google.charts.load('current', {
|
||
'packages':[ 'corechart']
|
||
});
|
||
|
||
</script>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-bibliography">
|
||
<section class="rprt-section-header" id="bibliography"><h2 id="header-bibliography"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-bibliography .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Bibliography</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Bibliography" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
|
||
<div class="rprt-section-body" style="">
|
||
<div class="generif-pubmed">
|
||
<h3 id="relatedarticlesinpubmed">
|
||
<a href="#" class="jig-ncbitoggler-open">Related articles in PubMed</a>
|
||
</h3>
|
||
<div class="generefbl-link">
|
||
<ol class="generef-link">
|
||
<li>
|
||
<a href="/pubmed/32943575/" ref="ordinalpos=1&ncbi_uid=10868&link_uid=32943575">Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2.</a>
|
||
<span class="pubmed-auth-date"> Li W, <em>et al</em>. Genes Dev, 2020 Oct 1. PMID 32943575, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC7528704/" ref="ordinalpos=0&ncbi_uid=10868&link_uid=PMC7528704">Free PMC Article</a></span></span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/29867130/" ref="ordinalpos=2&ncbi_uid=10868&link_uid=29867130">USP20 positively regulates tumorigenesis and chemoresistance through β-catenin stabilization.</a>
|
||
<span class="pubmed-auth-date"> Wu C, <em>et al</em>. Cell Death Differ, 2018 Nov. PMID 29867130, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC6180113/" ref="ordinalpos=0&ncbi_uid=10868&link_uid=PMC6180113">Free PMC Article</a></span></span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/33529762/" ref="ordinalpos=3&ncbi_uid=10868&link_uid=33529762">Expression, purification and characterization of the second DUSP domain of deubiquitinase USP20/VDU2.</a>
|
||
<span class="pubmed-auth-date"> Hu S, <em>et al</em>. Protein Expr Purif, 2021 May. PMID 33529762</span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/15776016/" ref="ordinalpos=4&ncbi_uid=10868&link_uid=15776016">VHL protein-interacting deubiquitinating enzyme 2 deubiquitinates and stabilizes HIF-1alpha.</a>
|
||
<span class="pubmed-auth-date"> Li Z, <em>et al</em>. EMBO Rep, 2005 Apr. PMID 15776016, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC1299287/" ref="ordinalpos=0&ncbi_uid=10868&link_uid=PMC1299287">Free PMC Article</a></span></span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/28167606/" ref="ordinalpos=5&ncbi_uid=10868&link_uid=28167606">Deubiquitinating Enzyme USP20 Regulates Extracellular Signal-Regulated Kinase 3 Stability and Biological Activity.</a>
|
||
<span class="pubmed-auth-date"> Mathien S, <em>et al</em>. Mol Cell Biol, 2017 May 1. PMID 28167606, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC5394282/" ref="ordinalpos=0&ncbi_uid=10868&link_uid=PMC5394282">Free PMC Article</a></span></span>
|
||
</li>
|
||
</ol>
|
||
<p class="see-all-pm">
|
||
<a href="/pubmed?LinkName=gene_pubmed&from_uid=10868" title="See all 69 citations in Pubmed">See all (69) citations in PubMed</a>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="generif-pubmed generif">
|
||
<h3 id="generifsgenereferencesintofunctions">
|
||
<a href="#" class="jig-ncbitoggler-open">GeneRIFs: Gene References Into Functions</a>
|
||
</h3>
|
||
<div>
|
||
<a href="/gene/about-generif" class="whatisthis">What's a GeneRIF?</a>
|
||
<div class="generefbl-link">
|
||
<ol class="generef-link">
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/37311534" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=10868&link_uid=37311534">Phosphorylation of USP20 on Ser334 by IRAK1 promotes IL-1beta-evoked signaling in vascular smooth muscle cells and vascular inflammation.</a>
|
||
<div id="gene-popper1" class="gene-rif-popper">Title: Phosphorylation of USP20 on Ser334 by IRAK1 promotes IL-1β-evoked signaling in vascular smooth muscle cells and vascular inflammation.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/33529762" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=10868&link_uid=33529762">Expression, purification and characterization of the second DUSP domain of deubiquitinase USP20/VDU2.</a>
|
||
<div id="gene-popper2" class="gene-rif-popper">Title: Expression, purification and characterization of the second DUSP domain of deubiquitinase USP20/VDU2.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/33792613" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=10868&link_uid=33792613">Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins.</a>
|
||
<div id="gene-popper3" class="gene-rif-popper">Title: Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/32943575" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=10868&link_uid=32943575">Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2.</a>
|
||
<div id="gene-popper4" class="gene-rif-popper">Title: Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/32354117" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=10868&link_uid=32354117">The Deubiquitinating Enzyme USP20 Regulates the TNFalpha-Induced NF-kappaB Signaling Pathway through Stabilization of p62.</a>
|
||
<div id="gene-popper5" class="gene-rif-popper">Title: The Deubiquitinating Enzyme USP20 Regulates the TNFα-Induced NF-κB Signaling Pathway through Stabilization of p62.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/31278784" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=10868&link_uid=31278784">Study revealed the molecular basis for the weak binding of USP20 N-terminal zinc-finger ubiquitin binding domain (ZnF-UBP) to mono-ubiquitin and poly-ubiquitin. The solution structure of USP20 ZnF-UBP domain consists of a central beta-sheet with either one alpha-helix or two alpha-helices packed on each side of the sheet. The overall structure of USP20 ZnF-UBP domain is stabilized by three coordinated zinc ions.</a>
|
||
<div id="gene-popper6" class="gene-rif-popper">Title: Structural and functional studies of USP20 ZnF-UBP domain by NMR.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/29867130" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=10868&link_uid=29867130">USP20 is a positive regulator of beta-catenin in cancer cell migration, invasion and tumor growth in vivo. Mechanistically, USP20 deubiquitinates and stabilizes beta-catenin and is a potential biomarker for predicting chemoresistance in cancer.</a>
|
||
<div id="gene-popper7" class="gene-rif-popper">Title: USP20 positively regulates tumorigenesis and chemoresistance through β-catenin stabilization.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/29487085" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=10868&link_uid=29487085">our results demonstrate a role of the USP20 deubiquitinating enzyme in acting as a critical regulator of ULK1 and show a novel mechanism of the autophagy process in terms of ULK1 stability.</a>
|
||
<div id="gene-popper8" class="gene-rif-popper">Title: The deubiquitinating enzyme USP20 stabilizes ULK1 and promotes autophagy initiation.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/28167606" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=10868&link_uid=28167606">USP20 regulates actin cytoskeleton organization and cell migration in a manner dependent on ERK3 expression. The results identify USP20 as a bona fide regulator of ERK3 stability and physiological functions.</a>
|
||
<div id="gene-popper9" class="gene-rif-popper">Title: Deubiquitinating Enzyme USP20 Regulates Extracellular Signal-Regulated Kinase 3 Stability and Biological Activity.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/25708858" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=10868&link_uid=25708858">we investigated the inter-action between PKM2 and USP20. Our results suggest a new molecular pathway in cancer metabolism through the regulation of PKM2.</a>
|
||
<div id="gene-popper10" class="gene-rif-popper">Title: Regulation of pyruvate kinase isozyme M2 is mediated by the ubiquitin-specific protease 20.</div>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
<div class="submit-genrif">
|
||
<span>Submit:</span>
|
||
<a href="/gene/submit-generif/?geneId=10868&sym=USP20&name=ubiquitin specific peptidase 20&org=Homo sapiens">New GeneRIF</a>
|
||
<a href="/RefSeq/update.cgi?geneid=10868&symbol=USP20;task=fixpub">Correction</a>
|
||
<a href="https://www.ncbi.nlm.nih.gov/gene?db=gene&report=generif&term=10868" class="seeall-generif">See all GeneRIFs (18)</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-phenotypes">
|
||
<section class="rprt-section-header" id="phenotypes">
|
||
<h2 id="header-phenotypes">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-phenotypes .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Phenotypes</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Phenotype" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body info-phenotype">
|
||
<p class="nochild-link">
|
||
<a href="/gtr/tests/?term=USP20[gene]">Find tests for this gene in the NIH Genetic Testing Registry (GTR)</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/gap/PheGenI?tab=1&gene=10868">Review eQTL and phenotype association data in this region using PheGenI</a>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-variation">
|
||
<section class="rprt-section-header" id="variation">
|
||
<h2 id="header-variation">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-variation .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Variation</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.variation" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<p class="nochild-link">
|
||
<a href="/clinvar/?term=USP20[gene]" ref="log$=recordlinks">See variants in ClinVar</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/dbvar?LinkName=gene_dbvar&from_uid=10868" ref="log$=recordlinks">See studies and variants in dbVar</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/variation/view/?q=10868[geneid]&assm=GCF_000001405.25" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh37.p13)">See Variation Viewer (GRCh37.p13)</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/variation/view/?q=10868[geneid]" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh38)">See Variation Viewer (GRCh38)</a>
|
||
</p>
|
||
<set></set>
|
||
<set></set>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-HIV-1-interactions">
|
||
<section class="rprt-section-header" id="HIV-1-interactions">
|
||
<h2 id="header-HIV-1-interactions">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-HIV-1-interactions .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">HIV-1 interactions</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.HIV1_interactions" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div class="fgrid">
|
||
<h3 id="replicationinteractions">Replication interactions</h3>
|
||
<table summary="replication interactions" class="jig-ncbigrid">
|
||
<thead>
|
||
<tr>
|
||
<th id="hivinter">Interaction</th>
|
||
<th id="hivpub">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="hivinter">Knockdown of ubiquitin specific peptidase 20 (USP20) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 18976975" href="/pubmed/18976975">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
<h3 id="proteininteractions">Protein interactions</h3>
|
||
<table summary="protein interactions" class="jig-ncbigrid">
|
||
<thead>
|
||
<tr>
|
||
<th id="hivprotein">Protein</th>
|
||
<th id="gene-hivprotein">Gene</th>
|
||
<th id="hivinter">Interaction</th>
|
||
<th id="hivpub">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="hivprotein">
|
||
<a href="/protein/9629358">Tat</a>
|
||
</td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155871">tat</a>
|
||
</td>
|
||
<td headers="hivinter">Expression of HIV-1 Tat downregulates the abundance of ubiquitin specific peptidase 20 (USP20) in the nucleoli of Jurkat T-cells</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 23166591" href="/pubmed/23166591">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
<p class="withnote">
|
||
<a class="note" href="/genome/viruses/retroviruses/hiv-1/interactions/">Go to the HIV-1, Human Interaction Database </a>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
<div class="rprt-section gene-interactions">
|
||
<section class="rprt-section-header" id="interactions">
|
||
<h2 id="header-interactions">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-interactions .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Interactions</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Interactions" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<table summary="Gene Interaction" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/10868/data/interaction/',webserviceParams: 'p$l=Ajax&p$debugoutput=off', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th id="inter-prod">Products</th>
|
||
<th id="inter-interactant">Interactant</th>
|
||
<th id="inter-otherGene">Other Gene</th>
|
||
<th id="inter-compl">Complex</th>
|
||
<th id="inter-source">Source</th>
|
||
<th id="inter-pubs">Pubs</th>
|
||
<th id="inter-desc">Description</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody></tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-general-gene-info">
|
||
<section class="rprt-section-header" id="general-gene-info">
|
||
<h2 id="header-general-gene-info">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-gene-info .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">General gene information</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.General_Gene_Information" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
|
||
<div class="rprt-section-body" style="">
|
||
<div id="gene-markers">
|
||
<h3 id="markers">
|
||
<a class="jig-ncbitoggler">Markers</a>
|
||
</h3>
|
||
<div>
|
||
<ul class="marker odd">
|
||
<li class="marker">SHGC-147266 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=175707%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=10868&link_uid=175707">UniSTS:175707</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">RH12701 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=90490%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=10868&link_uid=90490">UniSTS:90490</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">D9S1766 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=154238%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=10868&link_uid=154238">UniSTS:154238</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">SHGC-58438 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=71903%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=10868&link_uid=71903">UniSTS:71903</a></li></ul></li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div></div>
|
||
|
||
<div class="infosec">
|
||
<h3 id="homology">
|
||
<a class="jig-ncbitoggler-open">Homology</a>
|
||
</h3>
|
||
<ul class="geneinfo-subsec">
|
||
<li>
|
||
<a href="/gene/10868/ortholog/" id="ncbi-ortholog-link">NCBI Orthologs</a>
|
||
</li>
|
||
<a href="https://www.orthodb.org/?ncbi=10868" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=8178" target="_blank">
|
||
Orthologs from OrthoDB
|
||
</a>
|
||
</ul>
|
||
</div>
|
||
|
||
<!--<component id="Gene_InfoPathway"/>-->
|
||
|
||
<div class="infosec info-comment" id="info-comment">
|
||
<h3 id="CloneNames">
|
||
<a class="jig-ncbitoggler-open">Clone Names</a>
|
||
</h3>
|
||
<ul class="geneinfo-subsec">
|
||
<li>KIAA1003 </li>
|
||
</ul>
|
||
</div>
|
||
|
||
<div class="gene-ontology infosec">
|
||
<h3 id="gene-ontology">
|
||
<a class="jig-ncbitoggler-open">
|
||
<span>Gene Ontology</span>
|
||
</a>
|
||
<a target="_blank" href="http://www.ebi.ac.uk/GOA" class="g-ontology-src" title="Provided by GOA">Provided by GOA</a>
|
||
</h3>
|
||
<div class="ontology-tables">
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Function</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0001664">enables G protein-coupled receptor binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
|
||
<div id="evidence-code-1-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/19424180" target="_blank" title="PubMed ID 19424180" ref="ordinalpos=1&ncbi_uid=10868&link_uid=19424180">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0004843">enables cysteine-type deubiquitinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-2-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/19424180,26839314,29487085" target="_blank" title="PubMed ID 19424180,26839314,29487085" ref="ordinalpos=1&ncbi_uid=10868&link_uid=19424180,26839314,29487085">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0004843">enables cysteine-type deubiquitinase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-3-0" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0004197">enables cysteine-type endopeptidase activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
|
||
<div id="evidence-code-4-0" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/19424180" target="_blank" title="PubMed ID 19424180" ref="ordinalpos=1&ncbi_uid=10868&link_uid=19424180">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005515">enables protein binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
|
||
<div id="evidence-code-5-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/19615732,23166351,23486064,25416956,28514442,31515488,32296183,33961781" target="_blank" title="PubMed ID 19615732,23166351,23486064,25416956,28514442,31515488,32296183,33961781" ref="ordinalpos=1&ncbi_uid=10868&link_uid=19615732,23166351,23486064,25416956,28514442,31515488,32296183,33961781">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0008270">enables zinc ion binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-6-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Process</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0140374">involved_in antiviral innate immune response</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-1-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/27801882" target="_blank" title="PubMed ID 27801882" ref="ordinalpos=1&ncbi_uid=10868&link_uid=27801882">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0006897">involved_in endocytosis</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-2-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0043124">involved_in negative regulation of canonical NF-kappaB signal transduction</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-3-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/26839314" target="_blank" title="PubMed ID 26839314" ref="ordinalpos=1&ncbi_uid=10868&link_uid=26839314">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0007399">involved_in nervous system development</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-4-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0010508">involved_in positive regulation of autophagy</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-5-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/29487085" target="_blank" title="PubMed ID 29487085" ref="ordinalpos=1&ncbi_uid=10868&link_uid=29487085">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0071108">involved_in protein K48-linked deubiquitination</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-6-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/19424180" target="_blank" title="PubMed ID 19424180" ref="ordinalpos=1&ncbi_uid=10868&link_uid=19424180">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0070536">involved_in protein K63-linked deubiquitination</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-7-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/19424180" target="_blank" title="PubMed ID 19424180" ref="ordinalpos=1&ncbi_uid=10868&link_uid=19424180">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0016579">involved_in protein deubiquitination</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-8-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-8-1" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/19424180" target="_blank" title="PubMed ID 19424180" ref="ordinalpos=1&ncbi_uid=10868&link_uid=19424180">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0016579">involved_in protein deubiquitination</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-9-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-9-1" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0006508">involved_in proteolysis</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-10-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-10-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0008277">involved_in regulation of G protein-coupled receptor signaling pathway</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-11-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-11-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0008277">involved_in regulation of G protein-coupled receptor signaling pathway</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-12-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
|
||
<div id="evidence-code-12-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/19424180" target="_blank" title="PubMed ID 19424180" ref="ordinalpos=1&ncbi_uid=10868&link_uid=19424180">PubMed</a> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-config="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Component</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005813">located_in centrosome</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-1-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/23486064" target="_blank" title="PubMed ID 23486064" ref="ordinalpos=1&ncbi_uid=10868&link_uid=23486064">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005737">is_active_in cytoplasm</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IC</a>
|
||
<div id="evidence-code-2-2" class="ecode">Inferred by Curator<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/26839314,27801882,29487085" target="_blank" title="PubMed ID 26839314,27801882,29487085" ref="ordinalpos=1&ncbi_uid=10868&link_uid=26839314,27801882,29487085">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005829">located_in cytosol</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-3-2" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005783">located_in endoplasmic reticulum</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-4-2" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0048471">located_in perinuclear region of cytoplasm</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-5-2" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-general-protein-info">
|
||
<section class="rprt-section-header" id="general-protein-info">
|
||
<h2 id="header-general-protein-info">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-protein-info .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">General protein information</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.General_Protein_Information" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<dl>
|
||
<dt>Preferred Names</dt>
|
||
<dd>ubiquitin carboxyl-terminal hydrolase 20</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt>Names</dt>
|
||
<dd>deubiquitinating enzyme 20</dd>
|
||
<dd>pVHL-interacting deubiquitinating enzyme 2</dd>
|
||
<dd>ubiquitin thioesterase 20</dd>
|
||
<dd>ubiquitin thiolesterase 20</dd>
|
||
<dd>ubiquitin-specific-processing protease 20</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">NP_001008563.2</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.4.19.12">3.4.19.12</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">NP_001103773.2</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.4.19.12">3.4.19.12</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt class="heading">NP_006667.3</dt>
|
||
<dd>
|
||
<ul class="geneinfo-subsec">
|
||
<li>EC <a href="http://enzyme.expasy.org/EC/3.4.19.12">3.4.19.12</a></li>
|
||
</ul>
|
||
</dd>
|
||
</dl>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-reference-sequences">
|
||
<section class="rprt-section-header" id="reference-sequences">
|
||
<h2 id="header-reference-sequences">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-reference-sequences .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">NCBI Reference Sequences (RefSeq)</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.NCBI_Reference_Sequences_RefS" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<p>
|
||
<span class="new-icon">NEW</span>
|
||
<strong>Try the new <a href="/datasets/tables/genes/?table_type=transcripts&ids=10868&utm_source=gene&utm_medium=referral&utm_campaign=refseq" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report." data-ga-category="refseq" data-ga-action="click_datasets_link" data-ga-label="transcript_table">Transcript table</a></strong>
|
||
</p>
|
||
<h3 class="genomerefseqs gene_std_toggler" id="refseqset-independent">
|
||
<a class="jig-ncbitoggler-open">RefSeqs maintained independently of Annotated
|
||
Genomes</a>
|
||
</h3>
|
||
<div class="genomerefseqs_slave">
|
||
<p class="desc"> These reference sequences exist independently of genome builds. <a href="#refseq-expl" id="expl-refseg">Explain</a></p>
|
||
<p id="refseq-expl"> These reference sequences are curated independently of the genome
|
||
annotation cycle, so their versions may not match the RefSeq versions in the current
|
||
genome build. Identify version mismatches by comparing the version of the RefSeq in
|
||
this section to the one reported in <a href="#geneGenomic regions, transcripts, and products">Genomic regions,
|
||
transcripts, and products</a> above. </p>
|
||
<h4 id="genomic-p59399664">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NG_033097.2 RefSeqGene</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>5030..51400</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NG_033097.2?from=5030&to=51400&report=genbank" ref="ordinalpos=1&ncbi_uid=10868&link_uid=NG_033097.2?from=5030&to=51400&report=genbank">GenBank</a>, <a href="/nuccore/NG_033097.2?from=5030&to=51400&report=fasta" ref="ordinalpos=1&ncbi_uid=10868&link_uid=NG_033097.2?from=5030&to=51400&report=fasta">FASTA</a>, <a href="/nuccore/NG_033097.2?from=1&to=58355&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=10868&link_uid=NG_033097.2?from=1&to=58355&report=graph&content=5">Sequence Viewer (Graphics)</a>, <a href="ftp://ftp.ebi.ac.uk/pub/databases/lrgex/LRG_711.xml">LRG_711</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="mrnaandproteins-p59261616">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001008563.5">NM_001008563.5</a> → <a href="/protein/NP_001008563.2">NP_001008563.2</a> ubiquitin carboxyl-terminal hydrolase 20</p>
|
||
<p>
|
||
<a href="/ipg/NP_001008563.2/" ref="ncbi_uid=10868">See identical proteins and their annotated locations for NP_001008563.2</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (2) has different 5' and 3' non-coding, terminal exons, compared to transcript variant 1. All three transcript variants encode the same protein.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AL158207">AL158207</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS43892.1">CCDS43892.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/Q541F1" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">Q541F1</a>, <a href="https://www.uniprot.org/uniprot/Q8IXQ1" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">Q8IXQ1</a>, <a href="https://www.uniprot.org/uniprot/Q96LG5" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">Q96LG5</a>, <a href="https://www.uniprot.org/uniprot/Q9UQN8" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">Q9UQN8</a>, <a href="https://www.uniprot.org/uniprot/Q9UQP0" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">Q9UQP0</a>, <a href="https://www.uniprot.org/uniprot/Q9Y2K6" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">Q9Y2K6</a></dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000351122.1" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">ENSP00000351122.1</a>, <a href="http://www.ensembl.org/id/ENST00000358355.5" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">ENST00000358355.5</a></dd>
|
||
<dt class="clear"> Conserved Domains (5) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001008563.2">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=197831">smart00695</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">810</span> → <span class="cddto">895</span></dt>
|
||
<dd class="clearfix"> DUSP; Domain in ubiquitin-specific proteases</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=239139">cd02674</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">443</span> → <span class="cddto">683</span></dt>
|
||
<dd class="clearfix"> Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=271592">cl02553</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">144</span> → <span class="cddto">291</span></dt>
|
||
<dd class="clearfix"> Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=278850">pfam00443</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">144</span> → <span class="cddto">682</span></dt>
|
||
<dd class="clearfix"> UCH; Ubiquitin carboxyl-terminal hydrolase</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=280334">pfam02148</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">30</span> → <span class="cddto">90</span></dt>
|
||
<dd class="clearfix"> zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001110303.4">NM_001110303.4</a> → <a href="/protein/NP_001103773.2">NP_001103773.2</a> ubiquitin carboxyl-terminal hydrolase 20</p>
|
||
<p>
|
||
<a href="/ipg/NP_001103773.2/" ref="ncbi_uid=10868">See identical proteins and their annotated locations for NP_001103773.2</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (3) has a different 3' non-coding, terminal exon, compared to transcript variant 1. All three transcript variants encode the same protein.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AL158207">AL158207</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS43892.1">CCDS43892.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/Q541F1" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">Q541F1</a>, <a href="https://www.uniprot.org/uniprot/Q8IXQ1" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">Q8IXQ1</a>, <a href="https://www.uniprot.org/uniprot/Q96LG5" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">Q96LG5</a>, <a href="https://www.uniprot.org/uniprot/Q9UQN8" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">Q9UQN8</a>, <a href="https://www.uniprot.org/uniprot/Q9UQP0" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">Q9UQP0</a>, <a href="https://www.uniprot.org/uniprot/Q9Y2K6" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">Q9Y2K6</a></dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000361506.3" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">ENSP00000361506.3</a>, <a href="http://www.ensembl.org/id/ENST00000372429.8" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">ENST00000372429.8</a></dd>
|
||
<dt class="clear"> Conserved Domains (5) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001103773.2">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=197831">smart00695</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">810</span> → <span class="cddto">895</span></dt>
|
||
<dd class="clearfix"> DUSP; Domain in ubiquitin-specific proteases</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=239139">cd02674</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">443</span> → <span class="cddto">683</span></dt>
|
||
<dd class="clearfix"> Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=271592">cl02553</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">144</span> → <span class="cddto">291</span></dt>
|
||
<dd class="clearfix"> Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=278850">pfam00443</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">144</span> → <span class="cddto">682</span></dt>
|
||
<dd class="clearfix"> UCH; Ubiquitin carboxyl-terminal hydrolase</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=280334">pfam02148</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">30</span> → <span class="cddto">90</span></dt>
|
||
<dd class="clearfix"> zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_006676.8">NM_006676.8</a> → <a href="/protein/NP_006667.3">NP_006667.3</a> ubiquitin carboxyl-terminal hydrolase 20</p>
|
||
<p>
|
||
<a href="/ipg/NP_006667.3/" ref="ncbi_uid=10868">See identical proteins and their annotated locations for NP_006667.3</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (1) represents the longest transcript. All three transcript variants encode the same protein.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AL158207">AL158207</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS43892.1">CCDS43892.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/Q541F1" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">Q541F1</a>, <a href="https://www.uniprot.org/uniprot/Q8IXQ1" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">Q8IXQ1</a>, <a href="https://www.uniprot.org/uniprot/Q96LG5" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">Q96LG5</a>, <a href="https://www.uniprot.org/uniprot/Q9UQN8" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">Q9UQN8</a>, <a href="https://www.uniprot.org/uniprot/Q9UQP0" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">Q9UQP0</a>, <a href="https://www.uniprot.org/uniprot/Q9Y2K6" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">Q9Y2K6</a></dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000313811.4" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">ENSP00000313811.4</a>, <a href="http://www.ensembl.org/id/ENST00000315480.9" ref="itool=Gene_FullReport&PrId=5380&uid=10868&nlmid=&db=gene">ENST00000315480.9</a></dd>
|
||
<dt class="clear"> Conserved Domains (5) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_006667.3">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=197831">smart00695</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">810</span> → <span class="cddto">895</span></dt>
|
||
<dd class="clearfix"> DUSP; Domain in ubiquitin-specific proteases</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=239139">cd02674</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">443</span> → <span class="cddto">683</span></dt>
|
||
<dd class="clearfix"> Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=271592">cl02553</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">144</span> → <span class="cddto">291</span></dt>
|
||
<dd class="clearfix"> Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=278850">pfam00443</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">144</span> → <span class="cddto">682</span></dt>
|
||
<dd class="clearfix"> UCH; Ubiquitin carboxyl-terminal hydrolase</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=280334">pfam02148</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">30</span> → <span class="cddto">90</span></dt>
|
||
<dd class="clearfix"> zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
<h3 class="genomerefseqs gene_std_toggler" id="annotatedrefseq-title">
|
||
<a class="jig-ncbitoggler-open">RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08</a>
|
||
</h3>
|
||
<div class="genomerefseqs_slave">
|
||
<p class="desc"> The following sections contain reference sequences that belong to a
|
||
specific genome build. <a href="#" id="expl-genomes">Explain</a></p>
|
||
<p id="expl-genomes-desc" style="display:none">This section includes genomic Reference
|
||
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
|
||
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
|
||
assemblies. Model RNAs and proteins are also reported here.</p>
|
||
<h3 id="refseq-sequencedescription-p59242592">Reference GRCh38.p14 Primary Assembly</h3>
|
||
<h4 id="genomic-p59242592">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NC_000009.12 Reference GRCh38.p14 Primary Assembly</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>129835458..129881828</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NC_000009.12?from=129835458&to=129881828&report=genbank" ref="ordinalpos=1&ncbi_uid=10868&link_uid=NC_000009.12?from=129835458&to=129881828&report=genbank">GenBank</a>, <a href="/nuccore/NC_000009.12?from=129835458&to=129881828&report=fasta" ref="ordinalpos=1&ncbi_uid=10868&link_uid=NC_000009.12?from=129835458&to=129881828&report=fasta">FASTA</a>, <a href="/nuccore/NC_000009.12?from=129828501&to=129888783&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=10868&link_uid=NC_000009.12?from=129828501&to=129888783&report=graph&content=5">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h3 id="refseq-sequencedescription-p59251728">Alternate T2T-CHM13v2.0</h3>
|
||
<h4 id="genomic-p59251728">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NC_060933.1 Alternate T2T-CHM13v2.0</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>142040029..142086556</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NC_060933.1?from=142040029&to=142086556&report=genbank" ref="ordinalpos=1&ncbi_uid=10868&link_uid=NC_060933.1?from=142040029&to=142086556&report=genbank">GenBank</a>, <a href="/nuccore/NC_060933.1?from=142040029&to=142086556&report=fasta" ref="ordinalpos=1&ncbi_uid=10868&link_uid=NC_060933.1?from=142040029&to=142086556&report=fasta">FASTA</a>, <a href="/nuccore/NC_060933.1?from=142033049&to=142093534&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=10868&link_uid=NC_060933.1?from=142033049&to=142093534&report=graph&content=5">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-related-sequences">
|
||
<section class="rprt-section-header" id="related-sequences">
|
||
<h2 id="header-related-sequences">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-related-sequences .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Related sequences</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Related_Sequences" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<table id="proteinTblId" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/10868/data/related-sequences/',webserviceParams: 'p$l=Ajax', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th colspan="2" id="rs-nucleo">Nucleotide</th>
|
||
<th rowspan="2" id="rs-protein">Protein</th>
|
||
</tr>
|
||
<tr>
|
||
<th id="rs-heading">Heading</th>
|
||
<th id="rs-heading-acc">Accession and Version</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody></tbody>
|
||
</table>
|
||
<table id="proteinTblId" class="jig-ncbigrid" data-jigconfig="isPageable:true, pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th class="proteinTblTh" rowspan="2" id="rs-prot-acc">Protein Accession</th>
|
||
<th class="proteinTblTh" colspan="2" id="rs-link">Links</th>
|
||
</tr>
|
||
<tr>
|
||
<th id="rs-genepept">GenPept Link</th>
|
||
<th id="rs-uniprot">UniProtKB Link</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="rs-prot-acc">Q9Y2K6.2</td>
|
||
<td headers="rs-link rs-genepept">
|
||
<a href="/protein/116242837" ref="ordinalpos=1&ncbi_uid=10868&link_uid=116242837">GenPept</a>
|
||
</td>
|
||
<td>
|
||
<a href="https://www.uniprot.org/uniprot/Q9Y2K6">UniProtKB/Swiss-Prot:Q9Y2K6</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-additional-links">
|
||
|
||
<section class="rprt-section-header" id="additional-links"><h2 id="header-additional-links"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-additional-links .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Additional links</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Additional_Links" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
|
||
|
||
<div class="rprt-section-body" style="">
|
||
<div id="lsdb"><h3 class="withnote" id="locusspecificdatabases"><a class="jig-ncbitoggler-open">Locus-specific Databases</a></h3><div><ul class="locusdb"><li><a href="https://www.lovd.nl/USP20" ref="from_uid=10868" class="lsdblink">USP20 @ LOVD</a></li></ul></div></div>
|
||
|
||
<h3 class="withnote" id="genelinkout">
|
||
<a class="jig-ncbitoggler">Gene LinkOut</a>
|
||
</h3><div>
|
||
<p>The following <a href="https://www.ncbi.nlm.nih.gov/projects/linkout/index.html">LinkOut</a> resources are supplied by external providers. These providers are responsible for maintaining the links. </p>
|
||
<div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Chemical Information</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Interologous Interaction Database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://ophid.utoronto.ca/redirect/ncbi/human?proteins=10868" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=7911">
|
||
<span>Interologous Interaction Database</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>MilliporeSigma</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.sigmaaldrich.com/catalog/genes/USP20?lang=en&region=US" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=9978">
|
||
<span>USP20 products</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Molecular Biology Databases</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Bgee database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.bgee.org/gene/ENSG00000136878" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=10418">
|
||
<span>USP20 gene expression</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>BioGPS</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://biogps.org/gene/10868/" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=5059">
|
||
<span>BioGPS</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>BioGRID Open Repository of CRISPR Screens (ORCS)</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://orcs.thebiogrid.org/Gene/10868" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=10164">
|
||
<span>BioGRID CRISPR Screen Phenotypes (14 hits/1407 screens)</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>CTD: Comparative Toxicogenomics Database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://ctdbase.org/detail.go?type=gene&acc=10868" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=7845">
|
||
<span>CTD: Comparative Toxicogenomics Database - USP20</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Domain Mapping of Disease Mutations</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://bioinf.umbc.edu/DMDM/gene_prot_page.php?id=10868" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=7642">
|
||
<span>USP20</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>GlyGen glycoinformatics resource</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://glygen.org/protein/Q9Y2K6" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=10227">
|
||
<span>GlyGen glycoinformatics resource</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Human eFP Browser</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Skeletal_Immune_Digestive&modeInput=Absolute&primaryGene=10868" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Reproductive&modeInput=Absolute&primaryGene=10868" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Circulatory_Respiratory&modeInput=Absolute&primaryGene=10868" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li>Ingenuity Pathways Analysis</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://partnersolution.ingenuity.com/?cid=97ae3f91eab87a&p1=Entrez&p2=GV&s=&ipaUri=%2Fpa%2Fapi%2Fv2%2Fgeneview%3Fapplicationname%3DEntrez%26geneId%3D10868%26geneidtype%3Dentrezgene" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=5628">
|
||
<span>Ingenuity Pathways Analysis</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>InnateDB</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.innatedb.com/getGeneCard.do?id=89323" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=7894">
|
||
<span>InnateDB</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>InterMine</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.humanmine.org/humanmine/search?keyword=ENSG00000136878" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=9169">
|
||
<span>InterMine</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Kyoto Encyclopedia of Genes and Genomes</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.genome.jp/dbget-bin/www_bget?hsa:10868" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=5174">
|
||
<span>Kyoto Encyclopedia of Genes and Genomes</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>OMA Browser: Orthologous MAtrix</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN98870/" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN98868/" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN98869/" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>OrthoDB catalog of orthologs</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.orthodb.org/?ncbi=10868" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=8178">
|
||
<span>Orthologs</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>PhosphoSitePlus</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.phosphosite.org/entrezGeneIdAction.action?id=10868" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=7987">
|
||
<span>PhosphoSitePlus® - comprehensive post-translational modification resource</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>The Gene Wiki</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://en.wikipedia.org/wiki/USP20" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=6933">
|
||
<span>The Gene Wiki</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>The Weizmann Institute of Science GeneCards and MalaCards databases</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=USP20" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=8598">
|
||
<span>GeneCard for USP20</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Research Materials</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="order-rsc"></span>Addgene Non-profit plasmid repository</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://addgene.org//browse/gene/10868" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=5304">
|
||
<span>Get Plasmids - Addgene</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>Bio-Techne</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/usp20/proteins-enzymes?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=proteins" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>USP20 Proteins</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/usp20/lysates?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=lysates" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>USP20 Lysates</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/usp20/antibodies?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=antibodies" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>USP20 Antibodies</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li>ExactAntigen/Labome</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.labome.com/gene/human/USP20-antibody.html" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=5753">
|
||
<span>reagents</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.labome.com/review/gene/human/USP20-antibody.html" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=5753">
|
||
<span>reagent review</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GenScript latest version of gene cDNA ORF Clone</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.genscript.com/gene/10868" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=8012">
|
||
<span>GenScript latest version of gene cDNA ORF Clone</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GeneCopoeia Inc.</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=11&field=5&key=10868" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order shRNA clones</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=22&field=5&key=10868" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order promoter clone</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=1&field=5&key=10868" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order full-length ORF clone</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GeneTex Inc</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genetex.com/Product/Search?geneid=10868&type=01&page=1" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=8117">
|
||
<span>Find Quality Antibodies</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>Kazusa DNA Research Institute</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.kazusa.or.jp/kop/dsearch/symsearch.cgi?keyword=USP20;" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=3267">
|
||
<span>Kazusa DNA Research Institute</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>OriGene</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.origene.com/search?q=Usp20" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=7994">
|
||
<span>Order Usp20 cDNA clone/Protein/Antibody/RNAi</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Tools</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>GeneMANIA</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://genemania.org/link?o=9606&g=10868" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=7529">
|
||
<span>GeneMANIA</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open">
|
||
<span>Miscellaneous</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Reactome</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://reactome.org/content/query?q=UniProt:Q9Y2K6" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=4914">
|
||
<span>Reactome Entity:Q9Y2K6</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://reactome.org/PathwayBrowser/#/R-HSA-392499" ref="itool=Gene_FullReport&uid=10868&nlmid=&db=gene&log$=linkoutlink&PrId=4914">
|
||
<span>Reactome Event:Metabolism of proteins</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="urls-in-genombrowser" style="display:none">
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div><input type="hidden" class="section_status_input" name="status_checked" id="status_checked" value="" /><input type="hidden" class="section_status_input" name="status_open" id="status_open" value="summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links" /><input type="hidden" class="section_status_input" name="status_exist" id="status_exist" value="summary,context,region,expression,bibliography,phenotypes,variation,hiv,interactions,geneInfo,proteinInfo,refSeq,related,links" /><input type="hidden" class="section_status_input" name="status_closed" id="status_closed" value="" /><meta name="status_checked" content="" class="meta_section_status" /><meta name="status_open" content="summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links" class="meta_section_status" /><meta name="status_exist" content="summary,context,region,expression,bibliography,phenotypes,variation,hiv,interactions,geneInfo,proteinInfo,refSeq,related,links" class="meta_section_status" /><meta name="status_closed" content="" class="meta_section_status" /><script type="text/javascript">
|
||
|
||
var section_status_meta = {
|
||
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|
||
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|
||
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|
||
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|
||
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|
||
|
||
|
||
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|
||
for (var o in section_status_meta) {
|
||
var meta=document.createElement('meta');
|
||
meta.name = o;
|
||
meta.content = section_status_meta[o];
|
||
var attr = document.createAttribute('data-ignore-limit');
|
||
attr.value = 'true';
|
||
meta.setAttributeNode(attr);
|
||
document.getElementsByTagName('head')[0].appendChild(meta);
|
||
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|
||
*/
|
||
|
||
|
||
var __ncbi_sg_pingCallbacks_render_gene = function (data, evtObj, type) {
|
||
// data looks like {jsevent: "click", "link_id": "foo", ...}
|
||
// evtObj is the JS event object
|
||
// type is either "stat" (for applog) or "ga"
|
||
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||
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|
||
|
||
return extraData;
|
||
|
||
}
|
||
}
|
||
|
||
|
||
</script></div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last" id="sidebar_tabular">
|
||
<!-- sidebar close/hide button-->
|
||
<div class="ui-helper-clearfix">
|
||
<a href="#" id="sidecontent_2_pullout" style="float:right;" class="sidecontentpullout_local collapse_button"><span>Hide sidebar >></span></a>
|
||
</div>
|
||
<!-- end sidebar close/hide button-->
|
||
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div id="gene-sidebar">
|
||
<div>
|
||
<div class="portlet brieflink dis-table-of-contents">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Table of contents</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_TableOfContents" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li class="">
|
||
<a href="#summary">Summary</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#genomic-context">Genomic context</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#genomic-regions-transcripts-products">Genomic regions, transcripts, and products</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#gene-expression">Expression</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#bibliography">Bibliography</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#phenotypes">Phenotypes</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#variation">Variation</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#HIV-1-interactions">HIV-1 interactions</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#interactions">Interactions</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#general-gene-info">General gene information</a>
|
||
<div class="subsection-links"><a href="#gene-markers">Markers</a>, <a href="#CloneNames">Clone Names</a>, <a href="#homology">Homology</a>, <a href="#gene-ontology">Gene Ontology</a></div>
|
||
</li>
|
||
<li class="">
|
||
<a href="#general-protein-info">General protein information</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#reference-sequences">NCBI Reference Sequences (RefSeq)</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#related-sequences">Related sequences</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#additional-links">Additional links</a>
|
||
<div class="subsection-links">
|
||
<a href="#lsdb">Locus-specific Databases</a>
|
||
</div>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-genomesbrowser brieflink dis-genomesbrowser">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Genome Browsers</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GenomeBrowsers.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_GenomeBrowsers" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GenomeBrowsers.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="#">Loading...</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet dis-related-info brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related information</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="discovery_db_links" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content DiscoveryDbLinks">
|
||
<ul>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clone/order/gene/10868" ref="log$=recordlinks">Order cDNA clone</a>
|
||
<div class="brieflinkpop offscreen_noflow">Order cDNA clone</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/structure?LinkName=gene_structure&from_uid=10868" ref="log$=recordlinks">3D structures</a>
|
||
<div class="brieflinkpop offscreen_noflow">3D structure of a gene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_alltarget_list&from_uid=10868" ref="log$=recordlinks">BioAssay by Target (List)</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioAssays related to the gene by protein target or RNAi target</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_target&from_uid=10868" ref="log$=recordlinks">BioAssay, by Gene target</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem BioAssays done on the Gene target</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_rnai&from_uid=10868" ref="log$=recordlinks">BioAssays, RNAi Target, Tested</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioAssays that contain the gene as the target of a RNAi reagent</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/bioproject?LinkName=gene_bioproject&from_uid=10868" ref="log$=recordlinks">BioProjects</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioProjects related to a gene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/biosystems?LinkName=gene_biosystems&from_uid=10868" ref="log$=recordlinks">BioSystems</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioSystems</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/CCDS/CcdsBrowse.cgi?REQUEST=GENEID&DATA=10868" ref="log$=recordlinks">CCDS</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to CCDS</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar&from_uid=10868" ref="log$=recordlinks">ClinVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/cdd?LinkName=gene_cdd&from_uid=10868" ref="log$=recordlinks">Conserved Domains</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related CDD</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/dbvar?LinkName=gene_dbvar&from_uid=10868" ref="log$=recordlinks">dbVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link from Gene to dbVar</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc&from_uid=10868" ref="log$=recordlinks">Full text in PMC</a>
|
||
<div class="brieflinkpop offscreen_noflow">PMC links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc_nucleotide&from_uid=10868" ref="log$=recordlinks">Full text in PMC_nucleotide</a>
|
||
<div class="brieflinkpop offscreen_noflow">Full text in PubMedCentral identified from shared sequence links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/sparcle?LinkName=gene_sparcle&from_uid=10868" ref="log$=recordlinks">Functional Class</a>
|
||
<div class="brieflinkpop offscreen_noflow">Functional class of the sequence domain architecture</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_neighbors&from_uid=10868" ref="log$=recordlinks">Gene neighbors</a>
|
||
<div class="brieflinkpop offscreen_noflow">Overlapping genes and two nearest non-overlapping genes on either side</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_h3k4me3&from_uid=10868" ref="log$=recordlinks">Genes with a similar H3K4me3 profile</a>
|
||
<div class="brieflinkpop offscreen_noflow">Genes with a similar profile of promoter-activating H3K4me3 modifications across several tissue types</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/genome?LinkName=gene_genome&from_uid=10868" ref="log$=recordlinks">Genome</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Genome</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/geoprofiles?LinkName=gene_geoprofiles&from_uid=10868" ref="log$=recordlinks">GEO Profiles</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related GEO</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests/?term=10868[geneid]" ref="log$=recordlinks">GTR</a>
|
||
<div class="brieflinkpop offscreen_noflow">Tests for this gene in the NIH Genetic Testing Registry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/homologene?LinkName=gene_homologene&from_uid=10868" ref="log$=recordlinks">HomoloGene</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related HomoloGene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore&from_uid=10868" ref="log$=recordlinks">Nucleotide</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related Nucleotide entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/omim?LinkName=gene_omim&from_uid=10868" ref="log$=recordlinks">OMIM</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related OMIM entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/probe?LinkName=gene_probe&from_uid=10868" ref="log$=recordlinks">Probe</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Probe entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein&from_uid=10868" ref="log$=recordlinks">Protein</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related protein entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pccompound?LinkName=gene_pccompound&from_uid=10868" ref="log$=recordlinks">PubChem Compound</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem Compounds</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcsubstance?LinkName=gene_pcsubstance&from_uid=10868" ref="log$=recordlinks">PubChem Substance</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem Substances</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed&from_uid=10868" ref="log$=recordlinks">PubMed</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related PubMed entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_rif&from_uid=10868" ref="log$=recordlinks">PubMed (GeneRIF)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related PubMed article from GeneRIFs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_citedinomim&from_uid=10868" ref="log$=recordlinks">PubMed (OMIM)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Gene links to PubMed derived from omim_pubmed_cited links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_pmc_nucleotide&from_uid=10868" ref="log$=recordlinks">PubMed(nucleotide/PMC)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Citations in PubMed identified from shared sequence and PMC links.</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein_refseq&from_uid=10868" ref="log$=recordlinks">RefSeq Proteins</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Protein RefSeqs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore_refseqrna&from_uid=10868" ref="log$=recordlinks">RefSeq RNAs</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeq RNAs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore/1988229727?report=graph" ref="log$=recordlinks">RefSeqGene</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeqGenes</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar_specific&from_uid=10868" ref="log$=recordlinks">Related gene-specific medical variations</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/snp?LinkName=gene_snp&from_uid=10868" ref="log$=recordlinks">SNP</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related SNP records</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/taxonomy?LinkName=gene_taxonomy&from_uid=10868" ref="log$=recordlinks">Taxonomy</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related taxonomy entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/variation/view/?q=10868[geneid]" ref="log$=recordlinks">Variation Viewer</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Variants</div>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet dis-links-to-other-res brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Links to other resources</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_LinksTwo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:12619">HGNC</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.ensembl.org/id/ENSG00000136878">Ensembl</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.alliancegenome.org/gene/HGNC:12619">AllianceGenome</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=geneid&org=9606&l=10868">AceView</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://zearth.kazusa.or.jp/huge/gfpage/KIAA1003">HUGE</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.pharmgkb.org/gene/PA37245">PharmGKB</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position=NM_006676">UCSC</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.lovd.nl/USP20">USP20 @ LOVD</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://genecollections.nci.nih.gov/MGC/?ORG=Hs&LIST=BC039593">MGC</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://phgkb.cdc.gov/PHGKB/huGEPedia.action?firstQuery=USP20&geneID=10868&typeOption=gene&which=2&pubOrderType=pubD&typeSubmit=GO&check=y">HuGE Navigator</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.genome.jp/dbget-bin/www_bget?hsa:10868">KEGG</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://reactome.org/content/query?q=UniProt:Q9Y2K6">Reactome</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-general-info">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>General information</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_GeneralInfo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="/pmc/?term=PMC4383897+OR+PMC3013746+OR+PMC1761442+OR+PMC539985">About Gene</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3840">FAQ</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://ftp.ncbi.nlm.nih.gov/gene/">FTP site</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3841/">Help</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3842/">My NCBI help</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK21085/">NCBI Handbook</a>
|
||
</li>
|
||
<li>
|
||
<a href="/gene/statistics/">Statistics</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-related-sites">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related sites</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedSites.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_RelatedSites" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedSites.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/BLAST">BLAST</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/genome">Genome</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/bioproject">BioProject</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/genome/gdv/">Genome Data Viewer</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/geo">GEO</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/omim">OMIM</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/probe">Probe</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/RefSeq">RefSeq</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
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<div class="portlet brieflink dis-feedback">
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<div class="portlet_head">
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<div class="portlet_title">
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<h3>Feedback</h3>
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</div>
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<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Feedback.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_Feedback" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Feedback.Shutter"></a>
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<a href="https://support.ncbi.nlm.nih.gov/ics/support/ticketnewwizard.asp?style=classic&deptID=28049">Contact Help Desk</a>
|
||
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|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/RefSeq/update.cgi?geneid=10868&symbol=USP20">Submit Correction</a>
|
||
</li>
|
||
<li>
|
||
<a href="/gene/submit-generif?geneId=10868&sym=USP20&name=ubiquitin specific peptidase 20&org=Homo sapiens">Submit GeneRIF</a>
|
||
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|
||
</ul>
|
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<li>
|
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<a href="https://www.ncbi.nlm.nih.gov/mailman/listinfo/refseq-announce">RefSeq</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
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</div>
|
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<!-- <component id="Gene_RVFullReport.Gene_RightColMenuLinks"/>-->
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Clear
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<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOn" cmd="HTOff" href="?cmd=HTOff&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle">
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Turn Off
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Turn On
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|
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67c9ffe8a68b6b5afc230b66">USP20 ubiquitin specific peptidase 20 [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">USP20 ubiquitin specific peptidase 20 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:10868</div></div>
|
||
<div class="tertiary">Gene</div>
|
||
</li>
|
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<li class="ra_rcd ralinkpopper two_line">
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=2" href="/portal/utils/pageresolver.fcgi?recordid=67c9ffe5f4a390645ef2c64c">ubiquitin carboxyl-terminal hydrolase 20 [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">ubiquitin carboxyl-terminal hydrolase 20 [Homo sapiens]<div class="brieflinkpopdesc">gi|183397134|ref|NP_006667.3|</div></div>
|
||
<div class="tertiary">Protein</div>
|
||
</li>
|
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<li class="ra_rcd ralinkpopper two_line">
|
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=3" href="/portal/utils/pageresolver.fcgi?recordid=67c9ffe384f3725e59ef4f27">USP18 ubiquitin specific peptidase 18 [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">USP18 ubiquitin specific peptidase 18 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:11274</div></div>
|
||
<div class="tertiary">Gene</div>
|
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</li>
|
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<li class="ra_rcd ralinkpopper two_line">
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=4" href="/portal/utils/pageresolver.fcgi?recordid=67c9ffe284f3725e59ef4b03">ubl carboxyl-terminal hydrolase 18 [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">ubl carboxyl-terminal hydrolase 18 [Homo sapiens]<div class="brieflinkpopdesc">gi|32313610|ref|NP_059110.2|</div></div>
|
||
<div class="tertiary">Protein</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=5" href="/portal/utils/pageresolver.fcgi?recordid=67c9ffe0f4a390645ef2af8f">USP11 ubiquitin specific peptidase 11 [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">USP11 ubiquitin specific peptidase 11 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:8237</div></div>
|
||
<div class="tertiary">Gene</div>
|
||
</li>
|
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</ul>
|
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<p class="HTOn">Your browsing activity is empty.</p>
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<p class="HTOff">Activity recording is turned off.</p>
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<p id="turnOn" class="HTOff">
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<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryOn" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryOn" cmd="HTOn" href="?cmd=HTOn&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryOn">Turn recording back on</a>
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</p>
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<a class="seemore" href="/sites/myncbi/recentactivity">See more...</a>
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