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3997 lines
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315 KiB
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<h1 class="res_name"><a href="/gene/">Gene</a></h1>
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<h2 class="res_tagline">Genes and mapped phenotypes</h2>
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<div class="search"><div class="search_form"><label for="database" class="offscreen_noflow">Search database</label><select id="database"><optgroup label="Recent"><option value="pubmed">PubMed</option><option value="clinvar">ClinVar</option><option value="medgen">MedGen</option><option value="books" class="last">Books</option></optgroup><optgroup label="All"><option value="gquery">All Databases</option><option value="assembly" data-ac_dict="assembly">Assembly</option><option value="biocollections">Biocollections</option><option value="bioproject">BioProject</option><option value="biosample">BioSample</option><option value="books">Books</option><option value="clinvar">ClinVar</option><option value="cdd">Conserved Domains</option><option value="gap">dbGaP</option><option value="dbvar">dbVar</option><option value="gene" selected="selected" data-ac_dict="gene">Gene</option><option value="genome" data-ac_dict="genome">Genome</option><option value="gds">GEO DataSets</option><option value="geoprofiles">GEO Profiles</option><option value="gtr">GTR</option><option value="ipg">Identical Protein Groups</option><option value="medgen">MedGen</option><option value="mesh">MeSH</option><option value="nlmcatalog">NLM Catalog</option><option value="nuccore" data-ac_dict="nuccore">Nucleotide</option><option value="omim">OMIM</option><option value="pmc">PMC</option><option value="protein" data-ac_dict="protein">Protein</option><option value="proteinclusters">Protein Clusters</option><option value="protfam">Protein Family Models</option><option value="pcassay">PubChem BioAssay</option><option value="pccompound">PubChem Compound</option><option value="pcsubstance">PubChem Substance</option><option value="pubmed">PubMed</option><option value="snp">SNP</option><option value="sra">SRA</option><option value="structure">Structure</option><option value="taxonomy">Taxonomy</option><option value="toolkit">ToolKit</option><option value="toolkitall">ToolKitAll</option><option value="toolkitbookgh">ToolKitBookgh</option></optgroup></select><div class="nowrap"><label for="term" class="offscreen_noflow" accesskey="/">Search term</label><div class="nowrap"><input type="text" name="term" id="term" title="Search Gene. Use up and down arrows to choose an item from the autocomplete." value="" class="jig-ncbiclearbutton jig-ncbiautocomplete" data-jigconfig="dictionary:'gene',disableUrl:'NcbiSearchBarAutoComplCtrl'" autocomplete="off" data-sbconfig="ds:'no',pjs:'yes',afs:'yes'" /></div><button id="search" type="submit" class="button_search nowrap" cmd="go">Search</button></div></div><ul class="searchlinks inline_list"><set></set><li><a href="/gene/advanced">Advanced</a></li><li class="help"><a id="help" class="jig-ncbihelpwindow" target="ncbihelp" name="help" href="/books/NBK3841/">Help</a></li></ul></div>
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<input name="EntrezSystem2.PEntrez.Gene.Gene_PageController.PreviousPageName" sid="1" type="hidden" value="results" />
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<h2 class="offscreen_noflow">Result Filters</h2>
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<div class="facet_cont" data-db="gene" data-default_grps="fg_gene-sources,fg_categories,fg_sequence-content,fg_status" data-sd="db:'gene',op:'select',term:'',qk:'6064',linkname:'',idsfromresult:'10320',extra:''"><ul class="facet" data-filter_id="gene-sources" id="_gene-sources"><li class="filter_grp "><div class="clearfix"><h3>Gene sources</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="genomic">Genomic</a></li></ul></li></ul><ul class="facet" data-filter_id="categories" id="_categories"><li class="filter_grp "><div class="clearfix"><h3>Categories</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="alt-splicing">Alternatively spliced</a></li><li class="fil_val"><a href="#" data-value_id="annotated-genes">Annotated genes</a></li><li class="fil_val"><a href="#" data-value_id="gene-type-protein-coding">Protein-coding</a></li></ul></li></ul><ul class="facet" data-filter_id="sequence-content" id="_sequence-content"><li class="filter_grp "><div class="clearfix"><h3>Sequence content</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="seq-ccds">CCDS</a></li><li class="fil_val"><a href="#" data-value_id="seq-ensembl">Ensembl</a></li><li class="fil_val"><a href="#" data-value_id="refseq">RefSeq</a></li><li class="fil_val"><a href="#" data-value_id="seq-refseqgene">RefSeqGene</a></li></ul></li></ul><ul class="facet" data-filter_id="status" id="_status"><li class="filter_grp "><div class="clearfix"><h3>Status</h3><a href="#" data-value_id="" class="clear clear_show">Clear</a></div><ul><li class="fil_val selected"><a href="#" data-value_id="current-only">Current</a><span class="fcount">(1)</span></li></ul></li></ul><div id="chr-location-facet-wrapper" data-bid="MCID_67c9f672d74f676910466eb4" data-hid="MCID_67c90f2d64f30b25346ccae2" data-qky="6064" class="disabled" style="display:none"><ul class="facet" data-filter_id="chromosomal-region" id="_chromosomal-region" data-of="yes"><li class="filter_grp of_grp"><div class="clearfix"><h3>Chromosome locations</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><a id="facet_ofchromosomal-region" href="#facet_of_divchromosomal-region" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'middle left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '375px'" data-value_id="fetch_more">more...</a><div id="facet_of_divchromosomal-region" style="display:none;" class="of_popup"><h4>Chromosome locations</h4><label for="organism-filter" style="width:100%;margin-bottom:.2em;" class="">Select an organism by typing or scrolling</label><input type="text" placeholder="Enter text to narrow down the list" id="organism-filter" style="width:98%;" autocomplete="off" /><br /><div id="chr-region-tax-list"><select id="of_chromosomal-region" size="9" class="chr-region-tax-list" style="width:100%;"></select></div><div id="chr-location-info-ctrl" data-disabled="disabled"><div class="chr-field"><label for="chr-name">Chromosome</label><br /><select id="chr-name" class="chr-field" disabled="disabled"></select></div><div class="chr-field"><label for="chr-from">From</label><br /><input type="text" name="chr-from" id="chr-from" disabled="disabled" class="chr-field" /></div><div class="chr-field"><label for="chr-to">To</label><br /><input type="text" name="chr-to" id="chr-to" disabled="disabled" class="chr-field" /></div></div><div class="actions clearfix"><button class="jig-ncbibutton of_add apply-chr" data-jigconfig="'color': 'ui-ncbibutton-blue'">Apply</button></div></div></ul></li></ul></div><ul class="facet facet_reset"><li><a href="#" data-value_id="reset">Clear all</a></li></ul><ul class="facet_tools"><li><a id="more_filter_groups_link" href="#more_filter_groups" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'top left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '180px'">
|
||
Show additional filters</a></li><div id="more_filter_groups" style="display:none;" class="facets_dialog"><button class="ui-ncbipopper-close-button ui-ncbipopper-close-button-generated ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-blue" generated="true" role="button" aria-disabled="false"><span class="ui-button-text">x</span></button><h4>Additional filters</h4><ul class="filter_groups_more facet"><li><input type="checkbox" id="fg_gene-sources" /><label for="fg_gene-sources">Gene sources</label></li><li><input type="checkbox" id="fg_categories" /><label for="fg_categories">Categories</label></li><li><input type="checkbox" id="fg_sequence-content" /><label for="fg_sequence-content">Sequence content</label></li><li><input type="checkbox" id="fg_status" /><label for="fg_status">Status</label></li><li><input type="checkbox" id="fg_chromosomal-region" /><label for="fg_chromosomal-region">Chromosome locations</label></li><li><input id="fg_field_search" type="checkbox" /><label for="fg_field_search">Search fields</label></li></ul><div class="actions clearfix"><button class="filter_groups_more_apply jig-ncbibutton primary-action" id="filter_groups_apply" data-jigconfig="'color': 'ui-ncbibutton-blue'">Show</button></div></div></ul><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetsUrlFrag" sid="1" type="hidden" value="filters=current-only" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.FacetSubmitted" sid="1" type="hidden" value="false" /><input name="EntrezSystem2.PEntrez.Gene.Gene_Facets.BMFacets" sid="1" type="hidden" value="" /></div>
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|
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<span style="display: block; text-align: center;">S</span>
|
||
<span style="display: block; text-align: center;">I</span>
|
||
<span style="display: block; text-align: center;">D</span>
|
||
<span style="display: block; text-align: center;">E</span>
|
||
<span style="display: block; text-align: center;">B</span>
|
||
<span style="display: block; text-align: center;">A</span>
|
||
<span style="display: block; text-align: center;">R</span>
|
||
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|
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|
||
|
||
<div class="results_settings one_setting"><ul class="inline_list left display_settings"><li><a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Display" sid="0" href="#" class="jig-ncbipopper" data-jigconfig="triggerPosition : 'bottom center',destPosition : 'top center',destSelector : '#display_settings_menu_report', hasArrow : false,openEvent : 'click',closeEvent : 'click',isTriggerElementCloseClick: false,addCloseButton : false, groupName: 'entrez_pg'" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Display">Full Report<span href="#" class="tgt_dark"></span></a></li></ul><div id="display_settings_menu_report" class="disp_settings tabPopper"><fieldset class="format"><legend>Format</legend><ul class="column_list"><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="1" value="full_report" format="" id="full_report" checked="true" /><label for="full_report">Full Report</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="2" value="full_report" format="text" id="full_reporttext" /><label for="full_reporttext">Full Report (text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="3" value="expression" format="" id="expression" /><label for="expression">Expression</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="4" value="gene_table" format="" id="gene_table" /><label for="gene_table">Gene Table</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="5" value="gene_table" format="text" id="gene_tabletext" /><label for="gene_tabletext">Gene Table (text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="6" value="generif" format="" id="generif" /><label for="generif">GeneRIF</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="7" value="docsum" format="" id="docsum" /><label for="docsum">Summary</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="8" value="docsum" format="text" id="docsumtext" /><label for="docsumtext">Summary (text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="9" value="tabular" format="" id="tabular" /><label for="tabular">Tabular</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="10" value="tabular" format="text" id="tabulartext" /><label for="tabulartext">Tabular (text)</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="11" value="asn1" format="text" id="asn1text" /><label for="asn1text">ASN.1</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="12" value="xml" format="text" id="xmltext" /><label for="xmltext">XML</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.sPresentation" sid="13" value="uilist" format="text" id="uilisttext" /><label for="uilisttext">UI List</label></li></ul></fieldset></div><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SetDisplay" sid="1" class="button_apply ncbipopper-close-button" style="display:none">Apply</button><h4 class="content_header send_to align_right jig-ncbipopper" id="sendto" data-jigconfig="triggerPosition:'bottom center', destPosition : 'top center',destSelector : '#send_to_menu', hasArrow : false, openEvent : 'click',closeEvent : 'click', isTriggerElementCloseClick: false, addCloseButton:true, groupName: 'entrez_pg', adjustFit:'none'"><a href="#" sourceContent="send_to_menu" class="tgt_dark">Send to:</a><script type="text/javascript">
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||
</script></h4><div id="send_to_menu" class="tabPopper send_to"><fieldset><legend>Choose Destination</legend><ul class="column_list"><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="1" value="File" id="dest_File" /><label for="dest_File">File</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="2" value="AddToClipboard" id="dest_AddToClipboard" /><label for="dest_AddToClipboard">Clipboard</label></li><li><input type="radio" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendTo" sid="3" value="AddToCollections" id="dest_AddToCollections" /><label for="dest_AddToCollections">Collections</label></li></ul></fieldset><div class="submenu file" id="submenu_File" style="display: none;"><p id="submenu_File_hint" class="hidden"></p><ul><li><label for="file_format">Format</label><select id="file_format" name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FFormat" sid="1"><option value="full_report" format="text" selected="selected">Full Report (text)</option><option value="gene_table" format="text">Gene Table (text)</option><option value="docsum" format="text">Summary (text)</option><option value="tabular" format="text">Tabular (text)</option><option value="asn1" format="text">ASN.1</option><option value="xml" format="text">XML</option><option value="uilist" format="text">UI List</option></select></li></ul><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="1" class="button_apply file ncbipopper-close-button" type="submit" cmd="File">Create File</button></div><div class="submenu addtoclipboard" id="submenu_AddToClipboard" style="display: none;"><p id="submenu_AddToClipboard_hint" class="hidden"></p><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="2" class="button_apply clipboard ncbipopper-close-button" type="submit" cmd="AddToClipboard">Add to Clipboard</button></div><div class="submenu addtocollections" id="submenu_AddToCollections" style="display: none;"><p id="submenu_AddToCollections_hint" class="hidden"></p><button name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.SendToSubmit" sid="3" class="button_apply collections ncbipopper-close-button" type="submit" cmd="AddToCollections">Add to Collections</button></div></div><div><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FileFormat" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastPresentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Presentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastPageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Sort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastSort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.FileSort" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.Format" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.LastFormat" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevPageSize" sid="1" type="hidden" value="20" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevPresentation" sid="1" type="hidden" value="full_report" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_DisplayBar.PrevSort" sid="1" type="hidden" value="" /><input type="hidden" id="coll_startindex" name="CollectionStartIndex" value="1" /></div></div>
|
||
<div>
|
||
|
||
|
||
|
||
</div>
|
||
<div class="">
|
||
<div><span id="result_sel" class="nowrap"></span><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_ResultsController.ResultCount" sid="1" type="hidden" id="resultcount" value="1" /><input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_ResultsController.RunLastQuery" sid="1" type="hidden" /></div>
|
||
|
||
</div>
|
||
<div id="messagearea" class="empty">
|
||
|
||
|
||
|
||
|
||
</div>
|
||
<div class="rprt full-rprt">
|
||
<div>
|
||
<div class="rprt-header">
|
||
<input type="hidden" id="gene-tax-id" value="9606" />
|
||
<h1 class="title" id="gene-name"><span class="gn" style="padding-right:.5em;">IKZF1</span> IKAROS family zinc finger 1 [ <em class="tax">Homo sapiens</em> (human)
|
||
]
|
||
</h1>
|
||
<span class="geneid">Gene ID: 10320, updated on
|
||
4-Mar-2025</span>
|
||
</div>
|
||
<div class="download-datasets">
|
||
<script type="text/javascript" src="https://cdnjs.cloudflare.com/ajax/libs/axios/0.23.0/axios.min.js"></script>
|
||
<h4 class="download-datasets-popper jig-ncbipopper" id="download-asm" style="align-self:start" data-jigconfig="triggerPosition:'bottom center', destPosition : 'top center',destSelector : '#download-datasets-popper-menu', hasArrow : false, openEvent : 'click',closeEvent : 'click', isTriggerElementCloseClick: false, groupName: 'entrez_pg', adjustFit:'none'" role="button" aria-expanded="false" aria-haspopup="true">
|
||
<svg alt="download" class="dlbtn-icon" x="0px" y="0px" width="15px" height="15px" viewBox="0 0 60 60" enable-background="new 0 0 60 60" xml:space="preserve">
|
||
<g>
|
||
<polygon points="48.75,36.25 48.75,48.75 11.25,48.75 11.25,36.25 5,36.25 5,55 55,55 55,36.25 "></polygon>
|
||
<polygon points="42.5,23.75 36.25,23.75 36.25,5 23.75,5 23.75,23.75 17.5,23.75 30,42.5 "></polygon>
|
||
</g>
|
||
</svg>
|
||
<a href="#">Download Datasets</a>
|
||
</h4>
|
||
<div id="download-datasets-popper-menu" style="display:none;">
|
||
<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-gene-seq-fasta" value="FASTA_GENE" checked="checked" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-gene-seq-fasta">Gene Sequences (FASTA)</label>
|
||
</div>
|
||
<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-transcript-seq-fasta" value="FASTA_RNA" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-transcript-seq-fasta">Transcript sequences (FASTA)</label>
|
||
</div>
|
||
<div class="input-group">
|
||
<input type="checkbox" id="datasets-ft-protein-seq-fasta" value="FASTA_PROTEIN" class="download-datasets-included-seq" />
|
||
<label for="datasets-ft-protein-seq-fasta">Protein sequences(FASTA)</label>
|
||
</div>
|
||
<p style="margin-left:5px;">In addition, your package will include a detailed data report in both TSV and JSONL formats.</p>
|
||
<div class="input-group">
|
||
<label for="datasets-download-file-name">File name</label>
|
||
<input type="text" id="datasets-download-file-name" placeholder="Name your file" style="padding:5px;" value="IKZF1_datasets.zip" />
|
||
</div>
|
||
<input type="hidden" id="download-datasets-base-url" value="https://api.ncbi.nlm.nih.gov/datasets/v2alpha/gene/download" />
|
||
<input type="hidden" id="gene-id-value" value="10320" />
|
||
<button id="datasets-download-submit" data-ga-action="click_begin_download" data-ga-label="download" class="jig-ncbibutton ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-gray" role="button">
|
||
<span class="ui-button-text">Download</span>
|
||
</button>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-body">
|
||
|
||
|
||
<div class="rprt-section gene-summary">
|
||
<section class="rprt-section-header" id="summary">
|
||
<h2 id="header-summary">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-summary .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Summary</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Summary_2" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div id="summaryDiv" class="section">
|
||
<dl id="summaryDl">
|
||
<dt class="noline"> Official
|
||
Symbol</dt>
|
||
<dd class="noline">IKZF1<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
|
||
<dt> Official
|
||
Full Name</dt>
|
||
<dd>IKAROS family zinc finger 1<span class="prov">provided by <a href="http://www.genenames.org/" target="_blank" title="HUGO Gene Nomenclature Committee">HGNC</a></span></dd>
|
||
<dt>Primary source</dt>
|
||
<dd>
|
||
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:13176" data-gblink-text="Ensembl">HGNC:HGNC:13176</a>
|
||
</dd>
|
||
<dt>See related</dt>
|
||
<dd>
|
||
<a href="http://www.ensembl.org/id/ENSG00000185811" data-gblink-text="Ensembl" class="genome-browser-link" data-genome-browser-link-sort="5" data-gb-url="http://www.ensembl.org/loc/ENSG00000185811">Ensembl:ENSG00000185811</a>
|
||
<a href="https://www.ncbi.nlm.nih.gov/omim/603023" data-gblink-text="Ensembl" ref="ordinalpos=1&ncbi_uid=10320&link_uid=603023">MIM:603023;</a>
|
||
<a href="https://www.alliancegenome.org/gene/HGNC:13176" data-gblink-text="Ensembl" ref="ordinalpos=1&ncbi_uid=10320&link_uid=HGNC:13176">AllianceGenome:HGNC:13176</a>
|
||
</dd>
|
||
<dt>Gene type</dt>
|
||
<dd>protein coding</dd>
|
||
<dt>RefSeq status</dt>
|
||
<dd>REVIEWED</dd>
|
||
<dt>Organism</dt>
|
||
<dd class="tax">
|
||
<a href="/Taxonomy/Browser/wwwtax.cgi?id=9606" ref="ordinalpos=1&ncbi_uid=10320&link_uid=9606">Homo sapiens</a>
|
||
</dd>
|
||
<dt>Lineage</dt>
|
||
<dd class="tax">Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo</dd>
|
||
<dt>Also known as</dt>
|
||
<dd>IK1; LYF1; LyF-1; CVID13; IKAROS; PPP1R92; PRO0758; ZNFN1A1; Hs.54452</dd>
|
||
<dt>Summary</dt>
|
||
<dd>This gene encodes a transcription factor that belongs to the family of zinc-finger DNA-binding proteins associated with chromatin remodeling. The expression of this protein is restricted to the fetal and adult hemo-lymphopoietic system, and it functions as a regulator of lymphocyte differentiation. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. Most isoforms share a common C-terminal domain, which contains two zinc finger motifs that are required for hetero- or homo-dimerization, and for interactions with other proteins. The isoforms, however, differ in the number of N-terminal zinc finger motifs that bind DNA and in nuclear localization signal presence, resulting in members with and without DNA-binding properties. Only a few isoforms contain the requisite three or more N-terminal zinc motifs that confer high affinity binding to a specific core DNA sequence element in the promoters of target genes. The non-DNA-binding isoforms are largely found in the cytoplasm, and are thought to function as dominant-negative factors. Overexpression of some dominant-negative isoforms have been associated with B-cell malignancies, such as acute lymphoblastic leukemia (ALL). [provided by RefSeq, May 2014]</dd>
|
||
<dt>Expression</dt>
|
||
<dd>Biased expression in lymph node (RPKM 13.3), appendix (RPKM 8.6) and 10 other tissues <a href="#gene-expression">See more</a></dd>
|
||
<dt>Orthologs</dt>
|
||
<dd class="ortholog-links">
|
||
<a href="https://www.ncbi.nlm.nih.gov/gene/22778">mouse</a>
|
||
<a href="/gene/10320/ortholog/">all</a>
|
||
</dd>
|
||
<dt style="padding-top:.5em;">
|
||
<span class="new-icon">NEW</span>
|
||
</dt>
|
||
<dd style="padding-top:.5em;">
|
||
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/10320/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="gene_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Gene table</a></strong>
|
||
<br />
|
||
<strong>Try the new <a href="https://www.ncbi.nlm.nih.gov/datasets/gene/id/10320/products/" data-ga-category="summary" data-ga-action="click_datasets_link" data-ga-label="transcript_table" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report.">Transcript table</a></strong>
|
||
</dd>
|
||
</dl>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-genomic-context">
|
||
<section class="rprt-section-header" id="genomic-context">
|
||
<h2 id="header-genomic-context">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-context .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Genomic context</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Genomic_Context" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div class="gc_cont">
|
||
<div class="gt_cont_contents">
|
||
<div style="float:right"><span>See IKZF1 in </span><a href="/genome/gdv/?context=gene&acc=10320" class="link-to-gdv genome-browser-link" data-genome-browser-link-sort="1" data-acc="GCF_000001405.40">Genome Data Viewer</a> </div>
|
||
<dl class="dl-chr-info" style="float:left;margin-top:0;">
|
||
<dt>Location: </dt>
|
||
<dd>
|
||
<span style="display:inline-block;">7p12.2</span>
|
||
</dd>
|
||
</dl>
|
||
</div>
|
||
<dl class="dl-chr-info exon-count">
|
||
<dt>Exon count: </dt>
|
||
<dd>17</dd>
|
||
</dl>
|
||
<div class="ui-ncbigrid-outer-div" id="genomic-context-tbl-location">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="">
|
||
<thead>
|
||
<tr>
|
||
<th style="max-width:15%">Annotation release</th>
|
||
<th style="max-width:10%">Status</th>
|
||
<th>Assembly</th>
|
||
<th>
|
||
<span title="Chromosome">Chr</span>
|
||
</th>
|
||
<th>Location</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td>RS_2024_08</td>
|
||
<td>current</td>
|
||
<td>GRCh38.p14 (<a href="/assembly/GCF_000001405.40/" ref="ncbi_uid=10320&link_uid=GCF_000001405.40">GCF_000001405.40</a>)</td>
|
||
<td>7</td>
|
||
<td>NC_000007.14 (50303455..50405101) </td>
|
||
</tr>
|
||
<tr>
|
||
<td>RS_2024_08</td>
|
||
<td>current</td>
|
||
<td>T2T-CHM13v2.0 (<a href="/assembly/GCF_009914755.1/" ref="ncbi_uid=10320&link_uid=GCF_009914755.1">GCF_009914755.1</a>)</td>
|
||
<td>7</td>
|
||
<td>NC_060931.1 (50464429..50566317) </td>
|
||
</tr>
|
||
<tr>
|
||
<td>RS_2024_09</td>
|
||
<td>previous assembly</td>
|
||
<td>GRCh37.p13 (<a href="/assembly/GCF_000001405.25/" ref="ncbi_uid=10320&link_uid=GCF_000001405.25">GCF_000001405.25</a>)</td>
|
||
<td>7</td>
|
||
<td>NC_000007.13 (50343660..50472799) </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<p class="withnote margin_t2em"><strong>Chromosome 7 - NC_000007.14</strong><img usemap="#nbrMap10320_568815591" border="0" alt="Genomic Context describing neighboring genes" src="/gutils/geneneighb.fcgi?geneid=10320&nuc_gi=568815591&n0=LOC129998427&n1=LOC124901630&n2=SPMIP7&n3=LOC129998428&n4=LOC129998429&n5=LOC127409145&n6=LOC129998430&n7=LOC129998431&n8=LOC127409146&n9=LOC127409147&n10=LOC129998432&n11=LOC129998433&n12=LOC129998434&n13=LOC129998435&n14=LOC129998436&n15=LOC127409148&n16=IKZF1&n17=LOC129998437&n18=LOC129998438&n19=LOC129998439&n20=LOC127409149&n21=LOC127409150&n22=LOC129998440&n23=LOC129998441&n24=LOC106783492&n25=LOC129998442&n26=LOC129998443&n27=LOC129998444&n28=LOC127409151&n29=LOC127409152&n30=LOC127409153&n31=LOC127409154&n32=LOC124901631&n33=LOC129998445&n34=LOC127409155&n35=LOC129998446&n36=LOC129998447&n37=LOC129998448&n38=LOC127409156&n39=RNU6-1091P&n40=FIGNL1&n41=LOC126860033&n42=LOC123956149&n43=LOC129998449" /><map name="nbrMap10320_568815591" id="nbrMap10320_568815591">
|
||
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC124901630')" onMouseOut="hidetip()" coords="2,23,72,31" alt="Neighboring gene uncharacterized LOC124901630" href="/gene/124901630" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 18176')" onMouseOut="hidetip()" coords="2,35,72,43" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18176" href="/gene/129998427" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'sperm microtubule inner protein 7')" onMouseOut="hidetip()" coords="35,47,130,55" alt="Neighboring gene sperm microtubule inner protein 7" href="/gene/100130988" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 18177')" onMouseOut="hidetip()" coords="55,59,125,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18177" href="/gene/129998428" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 25991')" onMouseOut="hidetip()" coords="115,23,185,31" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25991" href="/gene/129998429" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr7:50246159-50247088')" onMouseOut="hidetip()" coords="116,35,186,43" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:50246159-50247088" href="/gene/127409145" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 25992')" onMouseOut="hidetip()" coords="120,71,190,79" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25992" href="/gene/129998430" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 25993')" onMouseOut="hidetip()" coords="120,83,190,91" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25993" href="/gene/129998431" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr7:50251182-50251682')" onMouseOut="hidetip()" coords="121,95,191,103" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:50251182-50251682" href="/gene/127409146" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr7:50251683-50252183')" onMouseOut="hidetip()" coords="121,107,191,115" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:50251683-50252183" href="/gene/127409147" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 18179')" onMouseOut="hidetip()" coords="123,119,193,127" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18179" href="/gene/129998432" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 25994')" onMouseOut="hidetip()" coords="177,47,247,55" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25994" href="/gene/129998433" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 25995')" onMouseOut="hidetip()" coords="180,59,250,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25995" href="/gene/129998434" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 18180')" onMouseOut="hidetip()" coords="185,131,255,139" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18180" href="/gene/129998435" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 25996')" onMouseOut="hidetip()" coords="192,23,262,31" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25996" href="/gene/129998436" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr7:50342269-50342770')" onMouseOut="hidetip()" coords="212,35,282,43" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:50342269-50342770" href="/gene/127409148" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 18181')" onMouseOut="hidetip()" coords="214,71,284,79" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18181" href="/gene/129998437" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 18182')" onMouseOut="hidetip()" coords="219,83,289,91" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18182" href="/gene/129998438" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 25997')" onMouseOut="hidetip()" coords="222,95,292,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25997" href="/gene/129998439" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr7:50354096-50354596')" onMouseOut="hidetip()" coords="224,107,294,115" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:50354096-50354596" href="/gene/127409149" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr7:50356151-50356651')" onMouseOut="hidetip()" coords="226,119,296,127" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:50356151-50356651" href="/gene/127409150" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 26000')" onMouseOut="hidetip()" coords="228,143,298,151" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26000" href="/gene/129998441" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 25999')" onMouseOut="hidetip()" coords="228,155,298,163" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 25999" href="/gene/129998440" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'conserved acetylation island sequence 3 enhancer')" onMouseOut="hidetip()" coords="229,167,299,175" alt="Neighboring gene conserved acetylation island sequence 3 enhancer" href="/gene/106783492" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 26001')" onMouseOut="hidetip()" coords="261,59,331,67" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26001" href="/gene/129998442" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 26002')" onMouseOut="hidetip()" coords="262,131,332,139" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26002" href="/gene/129998443" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 26003')" onMouseOut="hidetip()" coords="263,23,333,31" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26003" href="/gene/129998444" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:50427949-50428468')" onMouseOut="hidetip()" coords="270,179,340,187" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:50427949-50428468" href="/gene/127409151" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:50428469-50428986')" onMouseOut="hidetip()" coords="271,191,341,199" alt="Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:50428469-50428986" href="/gene/127409152" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K27ac hESC enhancer GRCh37_chr7:50446466-50446972')" onMouseOut="hidetip()" coords="289,35,359,43" alt="Neighboring gene H3K27ac hESC enhancer GRCh37_chr7:50446466-50446972" href="/gene/127409153" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'NANOG-H3K27ac hESC enhancer GRCh37_chr7:50446973-50447478')" onMouseOut="hidetip()" coords="289,71,359,79" alt="Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr7:50446973-50447478" href="/gene/127409154" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'uncharacterized LOC124901631')" onMouseOut="hidetip()" coords="296,83,366,91" alt="Neighboring gene uncharacterized LOC124901631" href="/gene/124901631" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 26004')" onMouseOut="hidetip()" coords="304,95,374,103" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26004" href="/gene/129998445" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'H3K4me1 hESC enhancer GRCh37_chr7:50477534-50478034')" onMouseOut="hidetip()" coords="320,107,390,115" alt="Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:50477534-50478034" href="/gene/127409155" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 26005')" onMouseOut="hidetip()" coords="321,119,391,127" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26005" href="/gene/129998446" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 26006')" onMouseOut="hidetip()" coords="322,143,392,151" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26006" href="/gene/129998447" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid active region 26007')" onMouseOut="hidetip()" coords="327,155,397,163" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26007" href="/gene/129998448" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'OCT4-NANOG hESC enhancer GRCh37_chr7:50488572-50489105')" onMouseOut="hidetip()" coords="331,167,401,175" alt="Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:50488572-50489105" href="/gene/127409156" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'CDK7 strongly-dependent group 2 enhancer GRCh37_chr7:50514049-50515248')" onMouseOut="hidetip()" coords="353,23,423,31" alt="Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr7:50514049-50515248" href="/gene/126860033" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'Sharpr-MPRA regulatory region 9826')" onMouseOut="hidetip()" coords="353,59,423,67" alt="Neighboring gene Sharpr-MPRA regulatory region 9826" href="/gene/123956149" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'ATAC-STARR-seq lymphoblastoid silent region 18183')" onMouseOut="hidetip()" coords="353,131,423,139" alt="Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18183" href="/gene/129998449" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'RNA, U6 small nuclear 1091, pseudogene')" onMouseOut="hidetip()" coords="356,179,416,187" alt="Neighboring gene RNA, U6 small nuclear 1091, pseudogene" href="/gene/106480637" />
|
||
<area shape="rect" onMouseOver="showtip(this,event,'fidgetin like 1')" onMouseOut="hidetip()" coords="383,35,423,43" alt="Neighboring gene fidgetin like 1" href="/gene/63979" />
|
||
</map>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-genomic-regions-transcripts-products">
|
||
<section class="rprt-section-header" id="genomic-regions-transcripts-products">
|
||
<h2 id="header-genomic-regions-transcripts-products">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-genomic-regions-transcripts-products .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Genomic regions, transcripts, and products</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Genomic_Regions_Transcripts_a" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<div style="text-align:right;">Go to <a href="#reference-sequences">reference sequence details</a></div>
|
||
</div>
|
||
<div>
|
||
<p class="choose">
|
||
<label for="accession" class="label">Genomic Sequence: </label>
|
||
<select name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.accessionList" sid="1" id="accessionList" data-taxid="9606" data-geneid="10320">
|
||
<option value="NC_000007.14_50303454_50405100">NC_000007.14 Chromosome 7 Reference GRCh38.p14 Primary Assembly</option>
|
||
<option value="NG_034231.1_5633_106018">NG_034231.1 RefSeqGene</option>
|
||
<option value="NC_060931.1_50464428_50566316">NC_060931.1 Chromosome 7 Alternate T2T-CHM13v2.0</option>
|
||
<option value="NC_000007.13_50343659_50472798">NC_000007.13 Chromosome 7 Reference GRCh37.p13 Primary Assembly</option>
|
||
</select>
|
||
</p>
|
||
</div>
|
||
<div id="NC_000007" class="divAccession">
|
||
<div class="seq-viewer">
|
||
<p class="note-link">
|
||
<strong>Go to nucleotide:</strong>
|
||
<a title="Nucleotide Graphic report" href="/nuccore/NC_000007.14?report=graph&from=50288207&to=50420347&app_context=Gene&assm_context=GCF_000001405.40" ref="ordinalpos=1&ncbi_uid=10320&link_uid=NC_000007.14">Graphics</a>
|
||
<a title="Nucleotide FASTA report" href="/nuccore/NC_000007.14?report=fasta&from=50303455&to=50405101" ref="ordinalpos=1&ncbi_uid=10320&link_uid=NC_000007.14">FASTA</a>
|
||
<a title="Nucleotide GenBank report" href="/nuccore/NC_000007.14?report=genbank&from=50303455&to=50405101" ref="ordinalpos=1&ncbi_uid=10320&link_uid=NC_000007.14">GenBank</a>
|
||
</p>
|
||
<div id="divNC_000007" class="SeqViewerApp" style="clear:both;" data-sv="appname=ncbigene&embedded=true&noslider=1&id=NC_000007.14&from=50288207&to=50420347&app_context=Gene&assm_context=GCF_000001405.40">
|
||
<a href="?appname=ncbigene&embedded=true&noslider=1&id=NC_000007.14&from=50288207&to=50420347&app_context=Gene&assm_context=GCF_000001405.40"></a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000007.14" sid="1" type="hidden" id="nucleotideLink_NC_000007_14_50303454_50405100" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_000007.14?report=graph&amp;from=50288207&amp;to=50420347&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" ref="ordinalpos=1&amp;ncbi_uid=10320&amp;link_uid=NC_000007.14">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_000007.14?report=fasta&amp;from=50303455&amp;to=50405101" ref="ordinalpos=1&amp;ncbi_uid=10320&amp;link_uid=NC_000007.14">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_000007.14?report=genbank&amp;from=50303455&amp;to=50405101" ref="ordinalpos=1&amp;ncbi_uid=10320&amp;link_uid=NC_000007.14">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000007.14" sid="1" type="hidden" id="relString_NC_000007_14_50303454_50405100" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000007.14&amp;from=50288207&amp;to=50420347&amp;app_context=Gene&amp;assm_context=GCF_000001405.40" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NG_034231.1" sid="1" type="hidden" id="nucleotideLink_NG_034231_1_5633_106018" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NG_034231.1?report=graph&amp;from=1&amp;to=121076&amp;tracks=[key:sequence_track,name:Sequence,display_name:Sequence,category:Sequence,annots:Sequence,ShowLabel:false][key:gene_model_track,name:Genes---Unnamed,display_name:Genes,annots:Unnamed,Options:ShowAllButGenes,SNPs:false,CDSProductFeats:false,ShowLabelsForAllFeatures:true,HighlightMode:2][key:SNP_track,name:SNP,annots:SNP,Layout:Adaptive][key:SNP_Bins_track,name:Clinical Variants][key:SNP_Bins_track,name:Cited Variants][key:GWAS_track,name:GWAS Tracks,display_name:Association Results][key:alignment_track,category:Alignments,annots:Unnamed][key:alignment_track,category:Alignments,annots:NA000079160.1][key:alignment_track,category:Alignments,annots:NA000010065.1]" ref="ordinalpos=1&amp;ncbi_uid=10320&amp;link_uid=NG_034231.1">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NG_034231.1?report=fasta&amp;from=5634&amp;to=106019" ref="ordinalpos=1&amp;ncbi_uid=10320&amp;link_uid=NG_034231.1">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NG_034231.1?report=genbank&amp;from=5634&amp;to=106019" ref="ordinalpos=1&amp;ncbi_uid=10320&amp;link_uid=NG_034231.1">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NG_034231.1" sid="1" type="hidden" id="relString_NG_034231_1_5633_106018" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NG_034231.1&amp;from=1&amp;to=121076&amp;tracks=[key:sequence_track,name:Sequence,display_name:Sequence,category:Sequence,annots:Sequence,ShowLabel:false][key:gene_model_track,name:Genes---Unnamed,display_name:Genes,annots:Unnamed,Options:ShowAllButGenes,SNPs:false,CDSProductFeats:false,ShowLabelsForAllFeatures:true,HighlightMode:2][key:SNP_track,name:SNP,annots:SNP,Layout:Adaptive][key:SNP_Bins_track,name:Clinical Variants][key:SNP_Bins_track,name:Cited Variants][key:GWAS_track,name:GWAS Tracks,display_name:Association Results][key:alignment_track,category:Alignments,annots:Unnamed][key:alignment_track,category:Alignments,annots:NA000079160.1][key:alignment_track,category:Alignments,annots:NA000010065.1]" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_060931.1" sid="1" type="hidden" id="nucleotideLink_NC_060931_1_50464428_50566316" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_060931.1?report=graph&amp;from=50449145&amp;to=50581599&amp;app_context=Gene&amp;assm_context=GCF_009914755.1" ref="ordinalpos=1&amp;ncbi_uid=10320&amp;link_uid=NC_060931.1">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_060931.1?report=fasta&amp;from=50464429&amp;to=50566317" ref="ordinalpos=1&amp;ncbi_uid=10320&amp;link_uid=NC_060931.1">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_060931.1?report=genbank&amp;from=50464429&amp;to=50566317" ref="ordinalpos=1&amp;ncbi_uid=10320&amp;link_uid=NC_060931.1">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_060931.1" sid="1" type="hidden" id="relString_NC_060931_1_50464428_50566316" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_060931.1&amp;from=50449145&amp;to=50581599&amp;app_context=Gene&amp;assm_context=GCF_009914755.1" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.nucleotideLink_NC_000007.13" sid="1" type="hidden" id="nucleotideLink_NC_000007_13_50343659_50472798" value="<p class="note-link"><strong>Go to nucleotide:</strong><a title="Nucleotide Graphic report" href="/nuccore/NC_000007.13?report=graph&amp;from=50324288&amp;to=50492169&amp;app_context=Gene&amp;assm_context=GCF_000001405.25" ref="ordinalpos=1&amp;ncbi_uid=10320&amp;link_uid=NC_000007.13">Graphics</a><a title="Nucleotide FASTA report" href="/nuccore/NC_000007.13?report=fasta&amp;from=50343660&amp;to=50472799" ref="ordinalpos=1&amp;ncbi_uid=10320&amp;link_uid=NC_000007.13">FASTA</a><a title="Nucleotide GenBank report" href="/nuccore/NC_000007.13?report=genbank&amp;from=50343660&amp;to=50472799" ref="ordinalpos=1&amp;ncbi_uid=10320&amp;link_uid=NC_000007.13">GenBank</a></p>" />
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_GenomicProductsP.relString_NC_000007.13" sid="1" type="hidden" id="relString_NC_000007_13_50343659_50472798" value="appname=ncbigene&amp;embedded=true&amp;noslider=1&amp;id=NC_000007.13&amp;from=50324288&amp;to=50492169&amp;app_context=Gene&amp;assm_context=GCF_000001405.25" />
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||
</div>
|
||
</div>
|
||
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|
||
<div class="rprt-section gene-gene-expression">
|
||
<section class="rprt-section-header" id="gene-expression">
|
||
<h2 id="header-gene-expression">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-gene-expression .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Expression</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Expression" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<div style="text-align:right;">
|
||
<a href="/gene/10320/?report=expression" data-url="/gene/10320/?report=expression" id="gene-expression-see-details">See details</a>
|
||
</div>
|
||
<div id="gene-expression-app" data-url="https://www.ncbi.nlm.nih.gov/gene/10320" data-report-type="summary">
|
||
<div>
|
||
<script type="text/javascript">
|
||
|
||
window.tissues_data = {'adrenal 10wk': {'id': '10320_Adrenal_10wk_PRJNA270632', 'gene': 10320, 'source_name': 'adrenal 10wk', 'full_rpkm': 0.180034, 'exp_rpkm': 0.18, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734413835829291}, 'adrenal 16wk': {'id': '10320_Adrenal_16wk_PRJNA270632', 'gene': 10320, 'source_name': 'adrenal 16wk', 'full_rpkm': 0.0453765, 'exp_rpkm': 0.0454, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734413835829292}, 'adrenal 18wk': {'id': '10320_Adrenal_18wk_PRJNA270632', 'gene': 10320, 'source_name': 'adrenal 18wk', 'full_rpkm': 0.0447648, 'exp_rpkm': 0.0448, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734413835829293}, 'adrenal 20wk': {'id': '10320_Adrenal_20wk_PRJNA270632', 'gene': 10320, 'source_name': 'adrenal 20wk', 'full_rpkm': 0.095583, 'exp_rpkm': 0.0956, 'var': 0.001426322, 'project_desc': 'PRJNA270632', '_version_': 1785734413835829294}, 'heart 10wk': {'id': '10320_Heart_10wk;_PRJNA270632', 'gene': 10320, 'source_name': 'heart 10wk', 'full_rpkm': 0.0656462, 'exp_rpkm': 0.0656, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734413835829295}, 'heart 11wk': {'id': '10320_Heart_11wk;_PRJNA270632', 'gene': 10320, 'source_name': 'heart 11wk', 'full_rpkm': 0.0508696, 'exp_rpkm': 0.0509, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734413835829296}, 'heart 17wk': {'id': '10320_Heart_17wk;_PRJNA270632', 'gene': 10320, 'source_name': 'heart 17wk', 'full_rpkm': 0.0332994, 'exp_rpkm': 0.0333, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734413835829297}, 'heart 18wk': {'id': '10320_Heart_18wk;_PRJNA270632', 'gene': 10320, 'source_name': 'heart 18wk', 'full_rpkm': 0.039682, 'exp_rpkm': 0.0397, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734413836877824}, 'heart 20wk': {'id': '10320_Heart_20wk_PRJNA270632', 'gene': 10320, 'source_name': 'heart 20wk', 'full_rpkm': 0.0636558, 'exp_rpkm': 0.0637, 'var': 0.0002034582, 'project_desc': 'PRJNA270632', '_version_': 1785734413836877825}, 'intestine 10wk': {'id': '10320_Intestine_10wk_PRJNA270632', 'gene': 10320, 'source_name': 'intestine 10wk', 'full_rpkm': 0.117307, 'exp_rpkm': 0.117, 'var': 0.00357982, 'project_desc': 'PRJNA270632', '_version_': 1785734413836877826}, 'intestine 11wk': {'id': '10320_Intestine_11wk_PRJNA270632', 'gene': 10320, 'source_name': 'intestine 11wk', 'full_rpkm': 0.0901156, 'exp_rpkm': 0.0901, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734413836877827}, 'intestine 15wk': {'id': '10320_Intestine_15wk_PRJNA270632', 'gene': 10320, 'source_name': 'intestine 15wk', 'full_rpkm': 0.252685, 'exp_rpkm': 0.253, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734413836877828}, 'intestine 17wk': {'id': '10320_Intestine_17wk_PRJNA270632', 'gene': 10320, 'source_name': 'intestine 17wk', 'full_rpkm': 0.228131, 'exp_rpkm': 0.228, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734413836877829}, 'intestine 20wk': {'id': '10320_Intestine_20wk_PRJNA270632', 'gene': 10320, 'source_name': 'intestine 20wk', 'full_rpkm': 0.406214, 'exp_rpkm': 0.406, 'var': 0.025708, 'project_desc': 'PRJNA270632', '_version_': 1785734413836877830}, 'kidney 10wk': {'id': '10320_Kidney_10wk_PRJNA270632', 'gene': 10320, 'source_name': 'kidney 10wk', 'full_rpkm': 0.076459, 'exp_rpkm': 0.0765, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734413836877831}, 'kidney 16wk': {'id': '10320_Kidney_16wk_PRJNA270632', 'gene': 10320, 'source_name': 'kidney 16wk', 'full_rpkm': 0.0411184, 'exp_rpkm': 0.0411, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734413836877832}, 'kidney 20wk': {'id': '10320_Kidney_20wk_PRJNA270632', 'gene': 10320, 'source_name': 'kidney 20wk', 'full_rpkm': 0.0140578, 'exp_rpkm': 0.0141, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734413836877833}, 'lung 10wk': {'id': '10320_Lung_10wk_PRJNA270632', 'gene': 10320, 'source_name': 'lung 10wk', 'full_rpkm': 0.0394075, 'exp_rpkm': 0.0394, 'var': 9.56568e-06, 'project_desc': 'PRJNA270632', '_version_': 1785734413836877834}, 'lung 17wk': {'id': '10320_Lung_17wk_PRJNA270632', 'gene': 10320, 'source_name': 'lung 17wk', 'full_rpkm': 0.14927, 'exp_rpkm': 0.149, 'var': 0.000827018, 'project_desc': 'PRJNA270632', '_version_': 1785734413836877835}, 'lung 20wk': {'id': '10320_Lung_20wk_PRJNA270632', 'gene': 10320, 'source_name': 'lung 20wk', 'full_rpkm': 0.118807, 'exp_rpkm': 0.119, 'var': 0.000607668, 'project_desc': 'PRJNA270632', '_version_': 1785734413836877836}, 'stomach 10wk': {'id': '10320_Stomach_10wk_PRJNA270632', 'gene': 10320, 'source_name': 'stomach 10wk', 'full_rpkm': 0.227069, 'exp_rpkm': 0.227, 'var': 0.0036069, 'project_desc': 'PRJNA270632', '_version_': 1785734413836877837}, 'stomach 16wk': {'id': '10320_Stomach_16wk_PRJNA270632', 'gene': 10320, 'source_name': 'stomach 16wk', 'full_rpkm': 0.117293, 'exp_rpkm': 0.117, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734413836877838}, 'stomach 18wk': {'id': '10320_Stomach_18wk_PRJNA270632', 'gene': 10320, 'source_name': 'stomach 18wk', 'full_rpkm': 0.224082, 'exp_rpkm': 0.224, 'var': 0.0, 'project_desc': 'PRJNA270632', '_version_': 1785734413836877839}, 'stomach 20wk': {'id': '10320_Stomach_20wk_PRJNA270632', 'gene': 10320, 'source_name': 'stomach 20wk', 'full_rpkm': 0.315327, 'exp_rpkm': 0.315, 'var': 0.0437388, 'project_desc': 'PRJNA270632', '_version_': 1785734413836877840}};
|
||
|
||
|
||
|
||
|
||
window.details_data = {"adrenal 10wk": [{"id": "metadata_9606_SAMN03267754", "gene": 10320, "sample_id": "SAMN03267754", "full_rpkm": 0.180034, "exp_rpkm": 0.18, "exp_total": 16414, "project_desc": "PRJNA270632", "_version_": 1785734387345653765, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 10wk", "exp_Mcount": 4852.92}], "adrenal 16wk": [{"id": "metadata_9606_SAMN03267755", "gene": 10320, "sample_id": "SAMN03267755", "full_rpkm": 0.0453765, "exp_rpkm": 0.0454, "exp_total": 6197, "project_desc": "PRJNA270632", "_version_": 1785734387345653764, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 16wk", "exp_Mcount": 7269.31}], "adrenal 18wk": [{"id": "metadata_9606_SAMN03267761", "gene": 10320, "sample_id": "SAMN03267761", "full_rpkm": 0.0447648, "exp_rpkm": 0.0448, "exp_total": 5614, "project_desc": "PRJNA270632", "_version_": 1785734387345653763, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "adrenal 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"metadata_9606_SAMN03267768", "gene": 10320, "sample_id": "SAMN03267768", "full_rpkm": 0.143458, "exp_rpkm": 0.143, "exp_total": 17121, "project_desc": "PRJNA270632", "_version_": 1785734387344605190, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "lung 20wk", "exp_Mcount": 6352.54}], "stomach 10wk": [{"id": "metadata_9606_SAMN03267773", "gene": 10320, "sample_id": "SAMN03267773", "full_rpkm": 0.167011, "exp_rpkm": 0.167, "exp_total": 20652, "project_desc": "PRJNA270632", "_version_": 1785734387344605187, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 10wk", "exp_Mcount": 6582.02}, {"id": "metadata_9606_SAMN03267779", "gene": 10320, "sample_id": "SAMN03267779", "full_rpkm": 0.287126, "exp_rpkm": 0.287, "exp_total": 39022, "project_desc": "PRJNA270632", "_version_": 1785734387344605188, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 10wk", "exp_Mcount": 7234.02}], "stomach 16wk": [{"id": "metadata_9606_SAMN03267774", "gene": 10320, "sample_id": "SAMN03267774", "full_rpkm": 0.117293, "exp_rpkm": 0.117, "exp_total": 13705, "project_desc": "PRJNA270632", "_version_": 1785734387344605186, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 16wk", "exp_Mcount": 6219.43}], "stomach 18wk": [{"id": "metadata_9606_SAMN03267771", "gene": 10320, "sample_id": "SAMN03267771", "full_rpkm": 0.224082, "exp_rpkm": 0.224, "exp_total": 24503, "project_desc": "PRJNA270632", "_version_": 1785734387344605185, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 18wk", "exp_Mcount": 5820.42}], "stomach 20wk": [{"id": "metadata_9606_SAMN03267765", "gene": 10320, "sample_id": "SAMN03267765", "full_rpkm": 0.611028, "exp_rpkm": 0.611, "exp_total": 51595, "project_desc": "PRJNA270632", "_version_": 1785734387342508032, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4494.58}, {"id": "metadata_9606_SAMN03267781", "gene": 10320, "sample_id": "SAMN03267781", "full_rpkm": 0.172837, "exp_rpkm": 0.173, "exp_total": 14827, "project_desc": "PRJNA270632", "_version_": 1785734387343556608, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4566.24}, {"id": "metadata_9606_SAMN03267783", "gene": 10320, "sample_id": "SAMN03267783", "full_rpkm": 0.162114, "exp_rpkm": 0.162, "exp_total": 14633, "project_desc": "PRJNA270632", "_version_": 1785734387344605184, "is_metadata": true, "is_sample": true, "taxid": 9606, "source_name": "stomach 20wk", "exp_Mcount": 4804.58}]}
|
||
window.taxId = 9606
|
||
</script>
|
||
|
||
|
||
<div>
|
||
|
||
|
||
|
||
<select name="p" id="project-selector">
|
||
|
||
|
||
<option value="SRP051249" selected="selected" data-bioproject="PRJNA270632">
|
||
|
||
Tissue-specific circular RNA induction during human fetal development
|
||
|
||
</option>
|
||
|
||
|
||
|
||
<option value="SRP056969" data-bioproject="PRJNA280600">
|
||
|
||
RNA sequencing of total RNA from 20 human tissues
|
||
|
||
|
||
</option>
|
||
|
||
|
||
|
||
<option value="ERP003613" data-bioproject="PRJEB4337">
|
||
|
||
HPA RNA-seq normal tissues
|
||
|
||
|
||
</option>
|
||
|
||
|
||
|
||
</select>
|
||
|
||
|
||
|
||
<ul id="project-summary">
|
||
<li id="project-summary-title">Project title:
|
||
|
||
Tissue-specific circular RNA induction during human fetal development
|
||
|
||
</li>
|
||
|
||
|
||
<li id="project-summary-desc">Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA</li>
|
||
|
||
|
||
|
||
<li id="project-summary-bioprojects">BioProject: <a href="/bioproject/PRJNA270632/">PRJNA270632</a>
|
||
</li>
|
||
|
||
<li id="project-summary-pubs">Publication:
|
||
|
||
|
||
<span><a href="/pubmed/26076956/">PMID 26076956</a></span>
|
||
|
||
</li>
|
||
|
||
|
||
<li id="project-summary-analysis-date">Analysis date: Mon Apr 2 22:54:59 2018</li>
|
||
|
||
</ul>
|
||
|
||
|
||
|
||
<div id="gene-expr-details" class="expression-chart"></div>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<script type="text/javascript" src="https://www.gstatic.com/charts/loader.js"></script>
|
||
<script type="text/javascript">
|
||
google.charts.load('current', {
|
||
'packages':[ 'corechart']
|
||
});
|
||
|
||
</script>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-bibliography">
|
||
<section class="rprt-section-header" id="bibliography"><h2 id="header-bibliography"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-bibliography .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Bibliography</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Bibliography" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
|
||
<div class="rprt-section-body" style="">
|
||
<div class="generif-pubmed">
|
||
<h3 id="relatedarticlesinpubmed">
|
||
<a href="#" class="jig-ncbitoggler-open">Related articles in PubMed</a>
|
||
</h3>
|
||
<div class="generefbl-link">
|
||
<ol class="generef-link">
|
||
<li>
|
||
<a href="/pubmed/29498923/" ref="ordinalpos=1&ncbi_uid=10320&link_uid=29498923">IKZF1(plus) Defines a New Minimal Residual Disease-Dependent Very-Poor Prognostic Profile in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia.</a>
|
||
<span class="pubmed-auth-date"> Stanulla M, <em>et al</em>. J Clin Oncol, 2018 Apr 20. PMID 29498923</span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/30022754/" ref="ordinalpos=2&ncbi_uid=10320&link_uid=30022754">[Effects of minimal residual disease level on day 33 of remission induction and IKZF1 genotype on the survival of children with B-lineage acute lymphoblastic leukemia].</a>
|
||
<span class="pubmed-auth-date"> Kuang WY, <em>et al</em>. Zhongguo Dang Dai Er Ke Za Zhi, 2018 Jul. PMID 30022754, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC7389200/" ref="ordinalpos=0&ncbi_uid=10320&link_uid=PMC7389200">Free PMC Article</a></span></span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/30004112/" ref="ordinalpos=3&ncbi_uid=10320&link_uid=30004112">Microdeletion of 7p12.1p13, including IKZF1, causes intellectual impairment, overgrowth, and susceptibility to leukaemia.</a>
|
||
<span class="pubmed-auth-date"> Järviaho T, <em>et al</em>. Br J Haematol, 2019 Apr. PMID 30004112</span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/29954930/" ref="ordinalpos=4&ncbi_uid=10320&link_uid=29954930">Immunomodulatory drugs downregulate IKZF1 leading to expansion of hematopoietic progenitors with concomitant block of megakaryocytic maturation.</a>
|
||
<span class="pubmed-auth-date"> Liu A, <em>et al</em>. Haematologica, 2018 Oct. PMID 29954930, <span class="pubmed-pmc-link"><a href="/pmc/articles/PMC6165797/" ref="ordinalpos=0&ncbi_uid=10320&link_uid=PMC6165797">Free PMC Article</a></span></span>
|
||
</li>
|
||
<li>
|
||
<a href="/pubmed/29942002/" ref="ordinalpos=5&ncbi_uid=10320&link_uid=29942002">Ikaros family zinc-finger 1 mutation is an independent factor for the poor prognosis of adult B-cell acute lymphoblastic leukemia, and allogeneic hematopoietic stem cell transplantation can improve clinical outcomes.</a>
|
||
<span class="pubmed-auth-date"> Tang S, <em>et al</em>. Bone Marrow Transplant, 2019 Feb. PMID 29942002</span>
|
||
</li>
|
||
</ol>
|
||
<p class="see-all-pm">
|
||
<a href="/pubmed?LinkName=gene_pubmed&from_uid=10320" title="See all 396 citations in Pubmed">See all (396) citations in PubMed</a>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="generif-pubmed generif">
|
||
<h3 id="generifsgenereferencesintofunctions">
|
||
<a href="#" class="jig-ncbitoggler-open">GeneRIFs: Gene References Into Functions</a>
|
||
</h3>
|
||
<div>
|
||
<a href="/gene/about-generif" class="whatisthis">What's a GeneRIF?</a>
|
||
<div class="generefbl-link">
|
||
<ol class="generef-link">
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/39111316" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=10320&link_uid=39111316">Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity.</a>
|
||
<div id="gene-popper1" class="gene-rif-popper">Title: Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/38579942" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=10320&link_uid=38579942">IgG4-related disease and B-cell malignancy due to an IKZF1 gain-of-function variant.</a>
|
||
<div id="gene-popper2" class="gene-rif-popper">Title: IgG4-related disease and B-cell malignancy due to an IKZF1 gain-of-function variant.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/38637852" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=10320&link_uid=38637852">IKZF1[PLUS] alterations contribute to outcome disparities in Hispanic/Latino children with B-lymphoblastic leukemia.</a>
|
||
<div id="gene-popper3" class="gene-rif-popper">Title: IKZF1(PLUS) alterations contribute to outcome disparities in Hispanic/Latino children with B-lymphoblastic leukemia.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/39112517" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=10320&link_uid=39112517">CCL2 mediated IKZF1 expression promotes M2 polarization of glioma-associated macrophages through CD84-SHP2 pathway.</a>
|
||
<div id="gene-popper4" class="gene-rif-popper">Title: CCL2 mediated IKZF1 expression promotes M2 polarization of glioma-associated macrophages through CD84-SHP2 pathway.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/38885295" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=10320&link_uid=38885295">IKZF1 and UBR4 gene variants drive autoimmunity and Th2 polarization in IgG4-related disease.</a>
|
||
<div id="gene-popper5" class="gene-rif-popper">Title: IKZF1 and UBR4 gene variants drive autoimmunity and Th2 polarization in IgG4-related disease.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/38780091" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=10320&link_uid=38780091">The GWAS SNP rs80207740 modulates erythrocyte traits via allele-specific binding of IKZF1 and targeting XPO7 gene.</a>
|
||
<div id="gene-popper6" class="gene-rif-popper">Title: The GWAS SNP rs80207740 modulates erythrocyte traits via allele-specific binding of IKZF1 and targeting XPO7 gene.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/38438084" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=10320&link_uid=38438084">Loss-of-phosphorylation of IKZF1 results in gain-of-function associated with immune dysregulation.</a>
|
||
<div id="gene-popper7" class="gene-rif-popper">Title: Loss-of-phosphorylation of IKZF1 results in gain-of-function associated with immune dysregulation.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/38734037" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=10320&link_uid=38734037">A novel IKZF1 variant in a family with autosomal dominant CVID: A case for expanding exon coverage in inborn errors of immunity.</a>
|
||
<div id="gene-popper8" class="gene-rif-popper">Title: A novel IKZF1 variant in a family with autosomal dominant CVID: A case for expanding exon coverage in inborn errors of immunity.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/38494589" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=10320&link_uid=38494589">IKZF1 rs4132601 and rs11978267 gene polymorphisms and paediatric systemic lupus erythematosus; relation to lupus nephritis.</a>
|
||
<div id="gene-popper9" class="gene-rif-popper">Title: IKZF1 rs4132601 and rs11978267 gene polymorphisms and paediatric systemic lupus erythematosus; relation to lupus nephritis.</div>
|
||
</li>
|
||
<li class="gene-rif-popper">
|
||
<a href="/pubmed/38537633" target="_blank" class="gene-rif-popper" ref="ordinalpos=1&ncbi_uid=10320&link_uid=38537633">A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children.</a>
|
||
<div id="gene-popper10" class="gene-rif-popper">Title: A noncoding regulatory variant in IKZF1 increases acute lymphoblastic leukemia risk in Hispanic/Latino children.</div>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
<div class="submit-genrif">
|
||
<span>Submit:</span>
|
||
<a href="/gene/submit-generif/?geneId=10320&sym=IKZF1&name=IKAROS family zinc finger 1&org=Homo sapiens">New GeneRIF</a>
|
||
<a href="/RefSeq/update.cgi?geneid=10320&symbol=IKZF1;task=fixpub">Correction</a>
|
||
<a href="https://www.ncbi.nlm.nih.gov/gene?db=gene&report=generif&term=10320" class="seeall-generif">See all GeneRIFs (301)</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-phenotypes">
|
||
<section class="rprt-section-header" id="phenotypes">
|
||
<h2 id="header-phenotypes">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-phenotypes .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Phenotypes</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Phenotype" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body info-phenotype">
|
||
<p class="nochild-link">
|
||
<a href="/gtr/tests/?term=IKZF1[gene]">Find tests for this gene in the NIH Genetic Testing Registry (GTR)</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/gap/PheGenI?tab=1&gene=10320">Review eQTL and phenotype association data in this region using PheGenI</a>
|
||
</p>
|
||
<div>
|
||
<h3 id="associatedconditions">Associated conditions</h3>
|
||
<table class="jig-ncbigrid gtr-associated-cond">
|
||
<thead>
|
||
<tr>
|
||
<th class="description">Description</th>
|
||
<th>Tests</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td>
|
||
<a href="/gtr/conditions/C4225173" ref="ncbi_uid=10320&link_uid=C4225173">Pancytopenia due to IKZF1 mutations</a>
|
||
<div class="gtr-associated-cond-extra">
|
||
<span class="gtr-associated-cond-extra-i">MedGen: <a href="/medgen/C4225173" ref="ncbi_uid=10320&link_uid=C4225173">C4225173</a></span>
|
||
<span class="gtr-associated-cond-extra-i">OMIM: <a href="https://www.ncbi.nlm.nih.gov/omim/616873" ref="ncbi_uid=10320"> 616873</a></span>
|
||
<span class="gtr-associated-cond-extra-i">GeneReviews: <span>Not available</span></span>
|
||
</div>
|
||
</td>
|
||
<td>
|
||
<a href="/gtr/tests/?term=C4225173[DISCUI]&condition=C4225173&compare_labs=1" ref="ncbi_uid=10320">Compare labs</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
<div>
|
||
<h3 id="ebigwascatalog">EBI GWAS Catalog</h3>
|
||
<table class="jig-ncbigrid gtr-associated-cond" data-jigconfig="isPageable: true, pageSize: 10">
|
||
<thead>
|
||
<tr>
|
||
<th class="description">Description</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td>Confirmation of Childhood Acute Lymphoblastic Leukemia Variants, ARID5B and IKZF1, and Interaction with Parental Environmental Exposures.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/25310577">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/25310577">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Discovery and refinement of loci associated with lipid levels.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/24097068">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/24097068">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/19838193">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/19838193">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/21102463">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/21102463">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Germline genomic variants associated with childhood acute lymphoblastic leukemia.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/19684603">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/19684603">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/19668339">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/19668339">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/23128233">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/23128233">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/22076464">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/22076464">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/23382691">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/23382691">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/19684604">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/19684604">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/23273568">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/23273568">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/19862010">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/19862010">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/23512250">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/23512250">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Seventy-five genetic loci influencing the human red blood cell.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/23222517">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/23222517">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
<tr>
|
||
<td>Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype.<div class="gtr-associated-cond-extra"><div class="gtr-associated-cond-extra-c"><span style="color:#000;">EBI GWAS Catalog</span><div><span class="gtr-associated-cond-extra-i"><a href="https://www.ebi.ac.uk/gwas/publications/23996088">EBI GWAS Catalog</a></span><span class="gtr-associated-cond-extra-i"><a href="/pubmed/23996088">PubMed</a></span></div></div></div></td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-variation">
|
||
<section class="rprt-section-header" id="variation">
|
||
<h2 id="header-variation">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-variation .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Variation</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.variation" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<p class="nochild-link">
|
||
<a href="/clinvar/?term=IKZF1[gene]" ref="log$=recordlinks">See variants in ClinVar</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/dbvar?LinkName=gene_dbvar&from_uid=10320" ref="log$=recordlinks">See studies and variants in dbVar</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/variation/view/?q=10320[geneid]&assm=GCF_000001405.25" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh37.p13)">See Variation Viewer (GRCh37.p13)</a>
|
||
</p>
|
||
<p class="nochild-link">
|
||
<a href="/variation/view/?q=10320[geneid]" ref="log$=recordlinks" data-genome-browser-link-sort="3" class="genome-browser-link" data-gblink-text="Variation Viewer (GRCh38)">See Variation Viewer (GRCh38)</a>
|
||
</p>
|
||
<set></set>
|
||
<set></set>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-HIV-1-interactions">
|
||
<section class="rprt-section-header" id="HIV-1-interactions">
|
||
<h2 id="header-HIV-1-interactions">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-HIV-1-interactions .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">HIV-1 interactions</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.HIV1_interactions" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div class="fgrid">
|
||
<h3 id="proteininteractions">Protein interactions</h3>
|
||
<table summary="protein interactions" class="jig-ncbigrid">
|
||
<thead>
|
||
<tr>
|
||
<th id="hivprotein">Protein</th>
|
||
<th id="gene-hivprotein">Gene</th>
|
||
<th id="hivinter">Interaction</th>
|
||
<th id="hivpub">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="hivprotein">
|
||
<a href="/protein/9629358">Tat</a>
|
||
</td>
|
||
<td headers="gene-hivprotein">
|
||
<a href="/gene/155871">tat</a>
|
||
</td>
|
||
<td headers="hivinter">Ikaros is identified to interact with HIV-1 Tat in Jurkat cell by GST pull-down and by WB</td>
|
||
<td headers="hivpub">
|
||
<a title="PubMed Id(s): 19454010" href="/pubmed/19454010">PubMed</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
<p class="withnote">
|
||
<a class="note" href="/genome/viruses/retroviruses/hiv-1/interactions/">Go to the HIV-1, Human Interaction Database </a>
|
||
</p>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-pathways">
|
||
<section class="rprt-section-header" id="pathways">
|
||
<h2 id="header-pathways">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-pathways .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Pathways from PubChem</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<ul class="geneinfo-subsec infopathway">
|
||
<iframe title="Pathways in which the gene target is involved" class="pubchem-widget" scrolling="no" src="https://pubchem.ncbi.nlm.nih.gov/gene/10320#section=Pathways&embed=true&hide_all_headings=true&page_size=25" style="border: 0; width: 100%;"></iframe>
|
||
<script type="text/javascript" src="https://pubchem.ncbi.nlm.nih.gov/pcfe/libs/iframeResizer.min.js"></script>
|
||
<script type="text/javascript">iFrameResize({log: false, checkOrigin: false}, '.pubchem-widget')</script>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-interactions">
|
||
<section class="rprt-section-header" id="interactions">
|
||
<h2 id="header-interactions">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-interactions .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Interactions</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Interactions" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<table summary="Gene Interaction" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/10320/data/interaction/',webserviceParams: 'p$l=Ajax&p$debugoutput=off', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th id="inter-prod">Products</th>
|
||
<th id="inter-interactant">Interactant</th>
|
||
<th id="inter-otherGene">Other Gene</th>
|
||
<th id="inter-compl">Complex</th>
|
||
<th id="inter-source">Source</th>
|
||
<th id="inter-pubs">Pubs</th>
|
||
<th id="inter-desc">Description</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody></tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-general-gene-info">
|
||
<section class="rprt-section-header" id="general-gene-info">
|
||
<h2 id="header-general-gene-info">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-gene-info .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">General gene information</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.General_Gene_Information" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
|
||
<div class="rprt-section-body" style="">
|
||
<div id="gene-markers">
|
||
<h3 id="markers">
|
||
<a class="jig-ncbitoggler">Markers</a>
|
||
</h3>
|
||
<div>
|
||
<ul class="marker odd">
|
||
<li class="marker">D11S2921 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=152074%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=10320&link_uid=152074">UniSTS:152074</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">D8S2278 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=473906%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=10320&link_uid=473906">UniSTS:473906</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">D8S2279 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=473907%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=10320&link_uid=473907">UniSTS:473907</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">RH64966 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=44603%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=10320&link_uid=44603">UniSTS:44603</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">SGC33450 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=74861%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=10320&link_uid=74861">UniSTS:74861</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">SHGC-36405 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=61345%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=10320&link_uid=61345">UniSTS:61345</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">RH65205 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=49089%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=10320&link_uid=49089">UniSTS:49089</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">GDB:1318324 (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=68556%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=10320&link_uid=68556">UniSTS:68556</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker odd">
|
||
<li class="marker">HSC183_(GAP_102_G) (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=255208%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=10320&link_uid=255208">UniSTS:255208</a></li></ul></li>
|
||
</ul>
|
||
<ul class="marker ">
|
||
<li class="marker">HSC186_(GAP_20_X) (e-PCR)<ul class="marker-link"><li><a href="https://www.ncbi.nlm.nih.gov/probe?term=255211%20%5BUniSTS%20ID%5D" ref="ordinalpos=1&ncbi_uid=10320&link_uid=255211">UniSTS:255211</a></li></ul></li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div></div>
|
||
|
||
<div class="infosec">
|
||
<h3 id="homology">
|
||
<a class="jig-ncbitoggler-open">Homology</a>
|
||
</h3>
|
||
<ul class="geneinfo-subsec">
|
||
<li>
|
||
<a href="/gene/10320/ortholog/" id="ncbi-ortholog-link">NCBI Orthologs</a>
|
||
</li>
|
||
<a href="https://www.orthodb.org/?ncbi=10320" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=8178" target="_blank">
|
||
Orthologs from OrthoDB
|
||
</a>
|
||
</ul>
|
||
</div>
|
||
|
||
<!--<component id="Gene_InfoPathway"/>-->
|
||
|
||
|
||
<div class="gene-ontology infosec">
|
||
<h3 id="gene-ontology">
|
||
<a class="jig-ncbitoggler-open">
|
||
<span>Gene Ontology</span>
|
||
</a>
|
||
<a target="_blank" href="http://www.ebi.ac.uk/GOA" class="g-ontology-src" title="Provided by GOA">Provided by GOA</a>
|
||
</h3>
|
||
<div class="ontology-tables">
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Function</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0003677">enables DNA binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-1-0" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/21548011,22106042" target="_blank" title="PubMed ID 21548011,22106042" ref="ordinalpos=1&ncbi_uid=10320&link_uid=21548011,22106042">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0003700">enables DNA-binding transcription factor activity</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-2-0" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0000978">enables RNA polymerase II cis-regulatory region sequence-specific DNA binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-3-0" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0042802">enables identical protein binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
|
||
<div id="evidence-code-4-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/32296183" target="_blank" title="PubMed ID 32296183" ref="ordinalpos=1&ncbi_uid=10320&link_uid=32296183">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005515">enables protein binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
|
||
<div id="evidence-code-5-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/15491138,21516116,24292623,24722188,25416956,25910212,26871637,27107012,28514442,29892012,31515488,32296183,33961781,39251607" target="_blank" title="PubMed ID 15491138,21516116,24292623,24722188,25416956,25910212,26871637,27107012,28514442,29892012,31515488,32296183,33961781,39251607" ref="ordinalpos=1&ncbi_uid=10320&link_uid=15491138,21516116,24292623,24722188,25416956,25910212,26871637,27107012,28514442,29892012,31515488,32296183,33961781,39251607">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0019904">enables protein domain specific binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IPI</a>
|
||
<div id="evidence-code-6-0" class="ecode">Inferred from Physical Interaction<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"><a href="/pubmed/15491138" target="_blank" title="PubMed ID 15491138" ref="ordinalpos=1&ncbi_uid=10320&link_uid=15491138">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-func">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0008270">enables zinc ion binding</a>
|
||
</td>
|
||
<td headers="ont-evi- ont-evi-code-">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-7-0', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-7-0" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi- ont-pub-"> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-jigconfig="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Process</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0006325">involved_in chromatin organization</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IEA</a>
|
||
<div id="evidence-code-1-1" class="ecode">Inferred from Electronic Annotation<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0030218">involved_in erythrocyte differentiation</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
|
||
<div id="evidence-code-2-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/17934067" target="_blank" title="PubMed ID 17934067" ref="ordinalpos=1&ncbi_uid=10320&link_uid=17934067">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0030098">involved_in lymphocyte differentiation</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
|
||
<div id="evidence-code-3-1" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/17934067" target="_blank" title="PubMed ID 17934067" ref="ordinalpos=1&ncbi_uid=10320&link_uid=17934067">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0007498">involved_in mesoderm development</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> TAS</a>
|
||
<div id="evidence-code-4-1" class="ecode">Traceable Author Statement<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"><a href="/pubmed/8543809" target="_blank" title="PubMed ID 8543809" ref="ordinalpos=1&ncbi_uid=10320&link_uid=8543809">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0045892">involved_in negative regulation of DNA-templated transcription</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> ISS</a>
|
||
<div id="evidence-code-5-1" class="ecode">Inferred from Sequence or Structural Similarity<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-comp">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0006357">involved_in regulation of transcription by RNA polymerase II</a>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-evi-code-2">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-1', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IBA</a>
|
||
<div id="evidence-code-6-1" class="ecode">Inferred from Biological aspect of Ancestor<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-2 ont-pub-2"> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
<div class="ui-ncbigrid-outer-div">
|
||
<div class="ui-ncbigrid-inner-div">
|
||
<table class="jig-ncbigrid" data-config="isPageable: true, pageSize : 25, isSortable: true, columnTypes: ['str', 'str', 'str']">
|
||
<thead>
|
||
<tr>
|
||
<th class="col1">Component</th>
|
||
<th style="width:12%;">Evidence Code</th>
|
||
<th style="width:10%;">Pubs</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005829">located_in cytosol</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-1-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-1-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005654">located_in nucleoplasm</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-2-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-2-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005634">located_in nucleus</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-3-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-3-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/21548011,22106042" target="_blank" title="PubMed ID 21548011,22106042" ref="ordinalpos=1&ncbi_uid=10320&link_uid=21548011,22106042">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0005721">located_in pericentric heterochromatin</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-4-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-4-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/21548011" target="_blank" title="PubMed ID 21548011" ref="ordinalpos=1&ncbi_uid=10320&link_uid=21548011">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0032991">part_of protein-containing complex</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-5-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IDA</a>
|
||
<div id="evidence-code-5-2" class="ecode">Inferred from Direct Assay<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/23071339" target="_blank" title="PubMed ID 23071339" ref="ordinalpos=1&ncbi_uid=10320&link_uid=23071339">PubMed</a> </td>
|
||
</tr>
|
||
<tr>
|
||
<td headers="ont-proc">
|
||
<a href="http://amigo.geneontology.org/amigo/term/GO:0032991">part_of protein-containing complex</a>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-evi-code-3">
|
||
<a class="jig-ncbipopper" href="http://geneontology.org/docs/guide-go-evidence-codes/" data-jigconfig="destSelector: '#evidence-code-6-2', hasArrow: true, openAnimation: 'none', closeAnimation: 'none', adjustFit: 'autoAdjust', triggerPosition: 'center right', destPosition: 'center left'"> IMP</a>
|
||
<div id="evidence-code-6-2" class="ecode">Inferred from Mutant Phenotype<br /><a href="http://geneontology.org/docs/guide-go-evidence-codes/">more info</a></div>
|
||
</td>
|
||
<td headers="ont-evi-3 ont-pub-3"><a href="/pubmed/15491138" target="_blank" title="PubMed ID 15491138" ref="ordinalpos=1&ncbi_uid=10320&link_uid=15491138">PubMed</a> </td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-general-protein-info">
|
||
<section class="rprt-section-header" id="general-protein-info">
|
||
<h2 id="header-general-protein-info">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-general-protein-info .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">General protein information</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.General_Protein_Information" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<dl>
|
||
<dt>Preferred Names</dt>
|
||
<dd>DNA-binding protein Ikaros</dd>
|
||
</dl>
|
||
<dl>
|
||
<dt>Names</dt>
|
||
<dd>CLL-associated antigen KW-6</dd>
|
||
<dd>ikaros family zinc finger protein 1</dd>
|
||
<dd>lymphoid transcription factor LyF-1</dd>
|
||
<dd>protein phosphatase 1, regulatory subunit 92</dd>
|
||
<dd>zinc finger protein, subfamily 1A, 1 (Ikaros)</dd>
|
||
</dl>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="rprt-section gene-reference-sequences">
|
||
<section class="rprt-section-header" id="reference-sequences">
|
||
<h2 id="header-reference-sequences">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-reference-sequences .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">NCBI Reference Sequences (RefSeq)</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.NCBI_Reference_Sequences_RefS" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<p>
|
||
<span class="new-icon">NEW</span>
|
||
<strong>Try the new <a href="/datasets/tables/genes/?table_type=transcripts&ids=10320&utm_source=gene&utm_medium=referral&utm_campaign=refseq" title="View selected attributes for an input list of genes and download datasets containing genomic, transcript and protein sequences along with a detailed data report." data-ga-category="refseq" data-ga-action="click_datasets_link" data-ga-label="transcript_table">Transcript table</a></strong>
|
||
</p>
|
||
<h3 class="genomerefseqs gene_std_toggler" id="refseqset-independent">
|
||
<a class="jig-ncbitoggler-open">RefSeqs maintained independently of Annotated
|
||
Genomes</a>
|
||
</h3>
|
||
<div class="genomerefseqs_slave">
|
||
<p class="desc"> These reference sequences exist independently of genome builds. <a href="#refseq-expl" id="expl-refseg">Explain</a></p>
|
||
<p id="refseq-expl"> These reference sequences are curated independently of the genome
|
||
annotation cycle, so their versions may not match the RefSeq versions in the current
|
||
genome build. Identify version mismatches by comparing the version of the RefSeq in
|
||
this section to the one reported in <a href="#geneGenomic regions, transcripts, and products">Genomic regions,
|
||
transcripts, and products</a> above. </p>
|
||
<h4 id="genomic-p154025824">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NG_034231.1 RefSeqGene</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>5634..106019</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NG_034231.1?from=5634&to=106019&report=genbank" ref="ordinalpos=1&ncbi_uid=10320&link_uid=NG_034231.1?from=5634&to=106019&report=genbank">GenBank</a>, <a href="/nuccore/NG_034231.1?from=5634&to=106019&report=fasta" ref="ordinalpos=1&ncbi_uid=10320&link_uid=NG_034231.1?from=5634&to=106019&report=fasta">FASTA</a>, <a href="/nuccore/NG_034231.1?from=1&to=121076&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=10320&link_uid=NG_034231.1?from=1&to=121076&report=graph&content=5">Sequence Viewer (Graphics)</a>, <a href="ftp://ftp.ebi.ac.uk/pub/databases/lrgex/LRG_1121.xml">LRG_1121</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="mrnaandproteins-p117124672">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001220765.3">NM_001220765.3</a> → <a href="/protein/NP_001207694.1">NP_001207694.1</a> DNA-binding protein Ikaros isoform 2</p>
|
||
<p>
|
||
<a href="/ipg/NP_001207694.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for NP_001207694.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (2) lacks an alternate in-frame exon in the central coding region, compared to variant 1. The encoded isoform (2, also known as Ikx) is shorter than isoform 1, and it contains three N-terminal zinc finger motifs for high affinity DNA binding (PMID:11489963). Both variants 2 and 14 encode isoform 2.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AY377974, BC018349, BM148203, JX459579">AY377974, BC018349, BM148203, JX459579</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS59055.1">CCDS59055.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q13422" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q13422</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/R9R4D9" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">R9R4D9</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000352123.5" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENSP00000352123.5</a>, <a href="http://www.ensembl.org/id/ENST00000359197.9" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENST00000359197.9</a></dd>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001207694.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">119</span> → <span class="cddto">139</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=404364">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">132</span> → <span class="cddto">156</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001220767.2">NM_001220767.2</a> → <a href="/protein/NP_001207696.1">NP_001207696.1</a> DNA-binding protein Ikaros isoform 4</p>
|
||
<p>
|
||
<a href="/ipg/NP_001207696.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for NP_001207696.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (4) lacks an alternate in-frame exon in the 5' coding region, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The encoded isoform (4, also known as Ik-2(del) as described in PMID:9892693) is shorter than isoform 1. This isoform contains three N-terminal zinc finger motifs for high affinity DNA binding (PMID:9892693).</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/JX459579, U40462">JX459579, U40462</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TMF3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TMF3</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001207696.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227381">COG5048</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1</span> → <span class="cddto">131</span></dt>
|
||
<dd class="clearfix"> COG5048; FOG: Zn-finger [General function prediction only]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">60</span> → <span class="cddto">80</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001220768.2">NM_001220768.2</a> → <a href="/protein/NP_001207697.1">NP_001207697.1</a> DNA-binding protein Ikaros isoform 5</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (5) lacks two consecutive in-frame exons in the central coding region, compared to variant 1. The encoded isoform (5, also known as Ik-3 as described in PMID:12937159) is shorter than isoform 1. This isoform contains three N-terminal zinc finger motifs for high affinity DNA binding (PMID:9892693).</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/JX459579, U40462">JX459579, U40462</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q13422" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q13422</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/R9R4D9" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">R9R4D9</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001207697.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">119</span> → <span class="cddto">139</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=404364">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">132</span> → <span class="cddto">156</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001220770.2">NM_001220770.2</a> → <a href="/protein/NP_001207699.1">NP_001207699.1</a> DNA-binding protein Ikaros isoform 7</p>
|
||
<p>
|
||
<a href="/ipg/NP_001207699.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for NP_001207699.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (7) lacks an alternate in-frame exon in both the 5' and central coding regions, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The encoded isoform (7, also known as Ik-4(del) as described in PMID:9892693), is shorter than isoform 1. This isoform contains only two N-terminal zinc finger motifs, and represents a non-DNA-binding, dominant-negative isoform (PMID:9892693).</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/JX459579, U40462">JX459579, U40462</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TMF3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TMF3</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001207699.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227381">COG5048</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1</span> → <span class="cddto">112</span></dt>
|
||
<dd class="clearfix"> COG5048; FOG: Zn-finger [General function prediction only]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">60</span> → <span class="cddto">80</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=395048">pfam00096</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">58</span> → <span class="cddto">80</span></dt>
|
||
<dd class="clearfix"> zf-C2H2; Zinc finger, C2H2 type</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=404364">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">72</span> → <span class="cddto">97</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001220771.2">NM_001220771.2</a> → <a href="/protein/NP_001207700.1">NP_001207700.1</a> DNA-binding protein Ikaros isoform 8</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (8) lacks three consecutive alternate in-frame exons in the central coding region, compared to variant 1. The encoded isoform (8, also known as Ik-5 as described in PMID:12937159) is shorter than isoform 1. This isoform contains only one N-terminal zinc finger motif, and represents a non-DNA-binding, dominant-negative isoform.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/BC018349, JX459579">BC018349, JX459579</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS69299.1">CCDS69299.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TMF3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TMF3</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000513806.1" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENSP00000513806.1</a>, <a href="http://www.ensembl.org/id/ENST00000698575.1" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENST00000698575.1</a></dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001291837.2">NM_001291837.2</a> → <a href="/protein/NP_001278766.1">NP_001278766.1</a> DNA-binding protein Ikaros isoform 2</p>
|
||
<p>
|
||
<a href="/ipg/NP_001278766.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for NP_001278766.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (14) differs in the 5' UTR, and lacks an alternate in-frame exon in the central coding region, compared to variant 1. The encoded isoform (2, also known as Ikx) is shorter than isoform 1, and it contains three N-terminal zinc finger motifs for high affinity DNA binding (PMID:11489963). Both variants 2 and 14 encode isoform 2.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/BC018349, DB122945, JX459579">BC018349, DB122945, JX459579</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS59055.1">CCDS59055.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q13422" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q13422</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/R9R4D9" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">R9R4D9</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000413025.1" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENSP00000413025.1</a>, <a href="http://www.ensembl.org/id/ENST00000439701.2" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENST00000439701.2</a></dd>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001278766.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">119</span> → <span class="cddto">139</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=404364">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">132</span> → <span class="cddto">156</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001291838.2">NM_001291838.2</a> → <a href="/protein/NP_001278767.1">NP_001278767.1</a> DNA-binding protein Ikaros isoform 3</p>
|
||
<p>
|
||
<a href="/ipg/NP_001278767.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for NP_001278767.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (Ik-2) differs in the 5' UTR, and lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. The encoded isoform (3, also known as Ik-2) is shorter than isoform 1, and is localized to the nucleus and contains three N-terminal zinc finger motifs for high affinity DNA binding (PMID:9892693).</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AK303586, DB122945, JX459579">AK303586, DB122945, JX459579</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS78233.1">CCDS78233.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q13422" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q13422</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/R9R4D9" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">R9R4D9</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000396554.1" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENSP00000396554.1</a>, <a href="http://www.ensembl.org/id/ENST00000438033.5" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENST00000438033.5</a></dd>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001278767.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227381">COG5048</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1</span> → <span class="cddto">131</span></dt>
|
||
<dd class="clearfix"> COG5048; FOG: Zn-finger [General function prediction only]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">60</span> → <span class="cddto">80</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001291839.2">NM_001291839.2</a> → <a href="/protein/NP_001278768.1">NP_001278768.1</a> DNA-binding protein Ikaros isoform 6</p>
|
||
<p>
|
||
<a href="/ipg/NP_001278768.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for NP_001278768.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (Ik-4) differs in the 5' UTR, and lacks an alternate in-frame exon in both the 5' and central coding regions, compared to variant 1. The encoded isoform (6, also known as Ik-4 as described in PMID:12937159), is shorter than isoform 1. This isoform contains only two N-terminal zinc finger motifs, and represents a non-DNA-binding, dominant-negative isoform (PMID:9892693).</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC233268, BC018349, DC391353, JX459579">AC233268, BC018349, DC391353, JX459579</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TMF3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TMF3</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001278768.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227381">COG5048</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1</span> → <span class="cddto">112</span></dt>
|
||
<dd class="clearfix"> COG5048; FOG: Zn-finger [General function prediction only]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">60</span> → <span class="cddto">80</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=395048">pfam00096</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">58</span> → <span class="cddto">80</span></dt>
|
||
<dd class="clearfix"> zf-C2H2; Zinc finger, C2H2 type</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=404364">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">72</span> → <span class="cddto">97</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001291840.1">NM_001291840.1</a> → <a href="/protein/NP_001278769.1">NP_001278769.1</a> DNA-binding protein Ikaros isoform Ik-6</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (Ik-6) lacks four consecutive in-frame exons in the central coding region, compared to variant 1. The encoded isoform (Ik-6) is shorter than isoform 1. This isoform contains no N-terminal zinc finger motifs, is localized to the cytoplasm and functions as a non-DNA-binding, dominant-negative isoform (PMIDs:12937159, 10463586).</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/JX459579, U40462">JX459579, U40462</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A0A0MRA0" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A0A0MRA0</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001291841.1">NM_001291841.1</a> → <a href="/protein/NP_001278770.1">NP_001278770.1</a> DNA-binding protein Ikaros isoform Ik-7</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (Ik-7) lacks two consecutive in-frame exons in the central coding region, compared to variant 1. The encoded isoform (Ik-7) is shorter than isoform 1. This isoform contains only one N-terminal zinc finger motif, and represents a non-DNA-binding, dominant-negative isoform (PMID:9892693).</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/JX459579, U40462">JX459579, U40462</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A087WU46" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A087WU46</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000478368.1" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENSP00000478368.1</a>, <a href="http://www.ensembl.org/id/ENST00000615491.4" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENST00000615491.4</a></dd>
|
||
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001278770.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">60</span> → <span class="cddto">81</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001291842.1">NM_001291842.1</a> → <a href="/protein/NP_001278771.1">NP_001278771.1</a> DNA-binding protein Ikaros isoform Ik-7(del)</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (Ik-7(del)) lacks two consecutive in-frame exons in the central coding region, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The encoded isoform (Ik-7(del)) is shorter than isoform 1. This isoform contains only one N-terminal zinc finger motif, and represents a non-DNA-binding, dominant-negative isoform (PMID:9892693).</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/JX459579, U40462">JX459579, U40462</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A087WU46" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A087WU46</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (1) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_001278771.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">60</span> → <span class="cddto">81</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001291843.1">NM_001291843.1</a> → <a href="/protein/NP_001278772.1">NP_001278772.1</a> DNA-binding protein Ikaros isoform Ik-8</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (Ik-8) lacks three consecutive in-frame exons in the central coding region, compared to variant 1. The encoded isoform (Ik-8) is shorter than isoform 1. This isoform contains no N-terminal zinc finger motifs, and represents a non-DNA-binding, dominant-negative isoform (PMID:9892693).</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/JX459579, U40462">JX459579, U40462</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A087WU46" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A087WU46</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001291844.1">NM_001291844.1</a> → <a href="/protein/NP_001278773.1">NP_001278773.1</a> DNA-binding protein Ikaros isoform Ik-8(del)</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (Ik-8(del)) lacks three consecutive in-frame exons in the central coding region, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The encoded isoform (Ik-8(del)) is shorter than isoform 1. This isoform contains no N-terminal zinc finger motifs, and represents a non-DNA-binding, dominant-negative isoform (PMID:9892693).</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/JX459579, U40462">JX459579, U40462</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A087WU46" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A087WU46</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001291845.2">NM_001291845.2</a> → <a href="/protein/NP_001278774.1">NP_001278774.1</a> DNA-binding protein Ikaros isoform 15</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (15) lacks five 3' exons but contains an alternate 3' terminal exon, and it thus differs in its 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (15) has a distinct C-terminus and is significantly shorter than isoform 1. This isoform contains no N-terminal zinc finger motifs and is likely non-DNA-binding.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC124014, BC064594, DB148957">AC124014, BC064594, DB148957</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS78232.1">CCDS78232.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/C9JTB0" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">C9JTB0</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000388478.1" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENSP00000388478.1</a>, <a href="http://www.ensembl.org/id/ENST00000413698.5" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENST00000413698.5</a></dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001291846.2">NM_001291846.2</a> → <a href="/protein/NP_001278775.1">NP_001278775.1</a> DNA-binding protein Ikaros isoform 16</p>
|
||
<p>
|
||
<a href="/ipg/NP_001278775.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for NP_001278775.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (16) lacks five 3' exons but contains two alternate 3' exons, and it thus differs in its 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (16) has a distinct C-terminus and is significantly shorter than isoform 1. This isoform contains no N-terminal zinc finger motifs and is likely non-DNA-binding. Both variants 16 and 17 encode isoform 16.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AW337855, BM148203, BU537824">AW337855, BM148203, BU537824</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS87502.1">CCDS87502.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A2R8Y4D3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A2R8Y4D3</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000493696.1" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENSP00000493696.1</a>, <a href="http://www.ensembl.org/id/ENST00000646110.1" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENST00000646110.1</a></dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001291847.2">NM_001291847.2</a> → <a href="/protein/NP_001278776.1">NP_001278776.1</a> DNA-binding protein Ikaros isoform 16</p>
|
||
<p>
|
||
<a href="/ipg/NP_001278776.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for NP_001278776.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (17) differs in the 5' UTR, and lacks five 3' exons but contains two alternate 3' exons, and it thus differs in its 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (16) has a distinct C-terminus and is significantly shorter than isoform 1. This isoform contains no N-terminal zinc finger motifs and is likely non-DNA-binding. Both variants 16 and 17 encode isoform 16.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AW337855, BU537824, DB122945">AW337855, BU537824, DB122945</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS87502.1">CCDS87502.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A2R8Y4D3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A2R8Y4D3</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000494180.1" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENSP00000494180.1</a>, <a href="http://www.ensembl.org/id/ENST00000492782.6" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENST00000492782.6</a></dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_001410879.1">NM_001410879.1</a> → <a href="/protein/NP_001397808.1">NP_001397808.1</a> DNA-binding protein Ikaros isoform 17</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/AC124014, AC233268">AC124014, AC233268</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS94102.1">CCDS94102.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TNQ0" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TNQ0</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/NM_006060.6">NM_006060.6</a> → <a href="/protein/NP_006051.1">NP_006051.1</a> DNA-binding protein Ikaros isoform 1</p>
|
||
<p>
|
||
<a href="/ipg/NP_006051.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for NP_006051.1</a>
|
||
</p>
|
||
<p style="background:#fff; margin-top:1em;">Status: REVIEWED</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>Transcript Variant: This variant (1) encodes isoform 1 (also known as Ik-1 as described in PMID:12937159). This isoform contains four N-terminal zinc finger motifs, binds DNA, and is localized to the nucleus.</dd>
|
||
<dt>Source sequence(s)</dt>
|
||
<dd class="wordwrap">
|
||
<a href="/nuccore/BM148203, JX459579, U40462">BM148203, JX459579, U40462</a>
|
||
</dd>
|
||
<dt>Consensus CDS</dt>
|
||
<dd>
|
||
<a href="/CCDS/CcdsBrowse.cgi?REQUEST=CCDS&GO=MainBrowse&DATA=CCDS75596.1">CCDS75596.1</a>
|
||
</dd>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A4D260" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A4D260</a>, <a href="https://www.uniprot.org/uniprot/B4E0Z1" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">B4E0Z1</a>, <a href="https://www.uniprot.org/uniprot/D3DVM5" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">D3DVM5</a>, <a href="https://www.uniprot.org/uniprot/O00598" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">O00598</a>, <a href="https://www.uniprot.org/uniprot/Q13422" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q13422</a>, <a href="https://www.uniprot.org/uniprot/Q53XL2" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q53XL2</a>, <a href="https://www.uniprot.org/uniprot/Q69BM4" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q69BM4</a>, <a href="https://www.uniprot.org/uniprot/Q8WVA3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q8WVA3</a></dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000331614.3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENSP00000331614.3</a>, <a href="http://www.ensembl.org/id/ENST00000331340.8" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENST00000331340.8</a></dd>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=NP_006051.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">119</span> → <span class="cddto">139</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=404364">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">132</span> → <span class="cddto">156</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
<h3 class="genomerefseqs gene_std_toggler" id="annotatedrefseq-title">
|
||
<a class="jig-ncbitoggler-open">RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08</a>
|
||
</h3>
|
||
<div class="genomerefseqs_slave">
|
||
<p class="desc"> The following sections contain reference sequences that belong to a
|
||
specific genome build. <a href="#" id="expl-genomes">Explain</a></p>
|
||
<p id="expl-genomes-desc" style="display:none">This section includes genomic Reference
|
||
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
|
||
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
|
||
assemblies. Model RNAs and proteins are also reported here.</p>
|
||
<h3 id="refseq-sequencedescription-p125893168">Reference GRCh38.p14 Primary Assembly</h3>
|
||
<h4 id="genomic-p125893168">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NC_000007.14 Reference GRCh38.p14 Primary Assembly</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>50303455..50405101</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NC_000007.14?from=50303455&to=50405101&report=genbank" ref="ordinalpos=1&ncbi_uid=10320&link_uid=NC_000007.14?from=50303455&to=50405101&report=genbank">GenBank</a>, <a href="/nuccore/NC_000007.14?from=50303455&to=50405101&report=fasta" ref="ordinalpos=1&ncbi_uid=10320&link_uid=NC_000007.14?from=50303455&to=50405101&report=fasta">FASTA</a>, <a href="/nuccore/NC_000007.14?from=50288207&to=50420347&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=10320&link_uid=NC_000007.14?from=50288207&to=50420347&report=graph&content=5">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="mrnaandproteins-p104307040">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011515058.3">XM_011515058.3</a> → <a href="/protein/XP_011513360.1">XP_011513360.1</a> DNA-binding protein Ikaros isoform X1</p>
|
||
<p>
|
||
<a href="/ipg/XP_011513360.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for XP_011513360.1</a>
|
||
</p>
|
||
<dl>
|
||
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011513360.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227381">COG5048</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">187</span> → <span class="cddto">343</span></dt>
|
||
<dd class="clearfix"> COG5048; FOG: Zn-finger [General function prediction only]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">163</span> → <span class="cddto">183</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=372612">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">176</span> → <span class="cddto">200</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011515059.4">XM_011515059.4</a> → <a href="/protein/XP_011513361.1">XP_011513361.1</a> DNA-binding protein Ikaros isoform X2</p>
|
||
<p>
|
||
<a href="/ipg/XP_011513361.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for XP_011513361.1</a>
|
||
</p>
|
||
<dl>
|
||
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011513361.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227381">COG5048</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">187</span> → <span class="cddto">529</span></dt>
|
||
<dd class="clearfix"> COG5048; FOG: Zn-finger [General function prediction only]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">163</span> → <span class="cddto">183</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=372612">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">176</span> → <span class="cddto">200</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011515067.4">XM_011515067.4</a> → <a href="/protein/XP_011513369.1">XP_011513369.1</a> DNA-binding protein Ikaros isoform X8</p>
|
||
<p>
|
||
<a href="/ipg/XP_011513369.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for XP_011513369.1</a>
|
||
</p>
|
||
<dl>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011513369.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">163</span> → <span class="cddto">183</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=372612">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">176</span> → <span class="cddto">200</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419727.1">XM_047419727.1</a> → <a href="/protein/XP_047275683.1">XP_047275683.1</a> DNA-binding protein Ikaros isoform X10</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011515071.3">XM_011515071.3</a> → <a href="/protein/XP_011513373.1">XP_011513373.1</a> DNA-binding protein Ikaros isoform X17</p>
|
||
<p>
|
||
<a href="/ipg/XP_011513373.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for XP_011513373.1</a>
|
||
</p>
|
||
<dl>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011513373.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227381">COG5048</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">101</span> → <span class="cddto">175</span></dt>
|
||
<dd class="clearfix"> COG5048; FOG: Zn-finger [General function prediction only]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">104</span> → <span class="cddto">124</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=278523">pfam00096</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">102</span> → <span class="cddto">124</span></dt>
|
||
<dd class="clearfix"> zf-C2H2; Zinc finger, C2H2 type</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=290200">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">116</span> → <span class="cddto">141</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419739.1">XM_047419739.1</a> → <a href="/protein/XP_047275695.1">XP_047275695.1</a> DNA-binding protein Ikaros isoform X19</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011515061.4">XM_011515061.4</a> → <a href="/protein/XP_011513363.1">XP_011513363.1</a> DNA-binding protein Ikaros isoform X4</p>
|
||
<p>
|
||
<a href="/ipg/XP_011513363.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for XP_011513363.1</a>
|
||
</p>
|
||
<dl>
|
||
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011513363.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227381">COG5048</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">167</span> → <span class="cddto">323</span></dt>
|
||
<dd class="clearfix"> COG5048; FOG: Zn-finger [General function prediction only]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">143</span> → <span class="cddto">163</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=372612">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">156</span> → <span class="cddto">180</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419723.1">XM_047419723.1</a> → <a href="/protein/XP_047275679.1">XP_047275679.1</a> DNA-binding protein Ikaros isoform X6</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011515070.3">XM_011515070.3</a> → <a href="/protein/XP_011513372.1">XP_011513372.1</a> DNA-binding protein Ikaros isoform X12</p>
|
||
<p>
|
||
<a href="/ipg/XP_011513372.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for XP_011513372.1</a>
|
||
</p>
|
||
<dl>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011513372.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">143</span> → <span class="cddto">163</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=372612">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">156</span> → <span class="cddto">180</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419731.1">XM_047419731.1</a> → <a href="/protein/XP_047275687.1">XP_047275687.1</a> DNA-binding protein Ikaros isoform X14</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011515072.3">XM_011515072.3</a> → <a href="/protein/XP_011513374.1">XP_011513374.1</a> DNA-binding protein Ikaros isoform X20</p>
|
||
<p>
|
||
<a href="/ipg/XP_011513374.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for XP_011513374.1</a>
|
||
</p>
|
||
<dl>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011513374.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227381">COG5048</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">25</span> → <span class="cddto">155</span></dt>
|
||
<dd class="clearfix"> COG5048; FOG: Zn-finger [General function prediction only]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">84</span> → <span class="cddto">104</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011515074.3">XM_011515074.3</a> → <a href="/protein/XP_011513376.1">XP_011513376.1</a> DNA-binding protein Ikaros isoform X23</p>
|
||
<p>
|
||
<a href="/ipg/XP_011513376.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for XP_011513376.1</a>
|
||
</p>
|
||
<dl>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011513376.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227381">COG5048</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">25</span> → <span class="cddto">155</span></dt>
|
||
<dd class="clearfix"> COG5048; FOG: Zn-finger [General function prediction only]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">84</span> → <span class="cddto">104</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011515077.3">XM_011515077.3</a> → <a href="/protein/XP_011513379.1">XP_011513379.1</a> DNA-binding protein Ikaros isoform X27</p>
|
||
<p>
|
||
<a href="/ipg/XP_011513379.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for XP_011513379.1</a>
|
||
</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TMF3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TMF3</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011513379.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227381">COG5048</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">25</span> → <span class="cddto">136</span></dt>
|
||
<dd class="clearfix"> COG5048; FOG: Zn-finger [General function prediction only]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">84</span> → <span class="cddto">104</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=333835">pfam00096</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">82</span> → <span class="cddto">104</span></dt>
|
||
<dd class="clearfix"> zf-C2H2; Zinc finger, C2H2 type</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=372612">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">96</span> → <span class="cddto">121</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011515078.3">XM_011515078.3</a> → <a href="/protein/XP_011513380.1">XP_011513380.1</a> DNA-binding protein Ikaros isoform X29</p>
|
||
<p>
|
||
<a href="/ipg/XP_011513380.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for XP_011513380.1</a>
|
||
</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TMF3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TMF3</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011513380.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227381">COG5048</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">25</span> → <span class="cddto">136</span></dt>
|
||
<dd class="clearfix"> COG5048; FOG: Zn-finger [General function prediction only]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">84</span> → <span class="cddto">104</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=333835">pfam00096</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">82</span> → <span class="cddto">104</span></dt>
|
||
<dd class="clearfix"> zf-C2H2; Zinc finger, C2H2 type</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=372612">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">96</span> → <span class="cddto">121</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419726.1">XM_047419726.1</a> → <a href="/protein/XP_047275682.1">XP_047275682.1</a> DNA-binding protein Ikaros isoform X9</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A4D260" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A4D260</a>, <a href="https://www.uniprot.org/uniprot/B4E0Z1" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">B4E0Z1</a>, <a href="https://www.uniprot.org/uniprot/D3DVM5" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">D3DVM5</a>, <a href="https://www.uniprot.org/uniprot/O00598" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">O00598</a>, <a href="https://www.uniprot.org/uniprot/Q13422" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q13422</a>, <a href="https://www.uniprot.org/uniprot/Q53XL2" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q53XL2</a>, <a href="https://www.uniprot.org/uniprot/Q69BM4" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q69BM4</a>, <a href="https://www.uniprot.org/uniprot/Q8WVA3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q8WVA3</a></dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419729.1">XM_047419729.1</a> → <a href="/protein/XP_047275685.1">XP_047275685.1</a> DNA-binding protein Ikaros isoform X11</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419734.1">XM_047419734.1</a> → <a href="/protein/XP_047275690.1">XP_047275690.1</a> DNA-binding protein Ikaros isoform X16</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419736.1">XM_047419736.1</a> → <a href="/protein/XP_047275692.1">XP_047275692.1</a> DNA-binding protein Ikaros isoform X18</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419745.1">XM_047419745.1</a> → <a href="/protein/XP_047275701.1">XP_047275701.1</a> DNA-binding protein Ikaros isoform X25</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419747.1">XM_047419747.1</a> → <a href="/protein/XP_047275703.1">XP_047275703.1</a> DNA-binding protein Ikaros isoform X26</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TMF3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TMF3</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011515063.3">XM_011515063.3</a> → <a href="/protein/XP_011513365.1">XP_011513365.1</a> DNA-binding protein Ikaros isoform X5</p>
|
||
<p>
|
||
<a href="/ipg/XP_011513365.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for XP_011513365.1</a>
|
||
</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TNQ0" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TNQ0</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000513805.1" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENSP00000513805.1</a>, <a href="http://www.ensembl.org/id/ENST00000698574.1" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENST00000698574.1</a></dd>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011513365.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">139</span> → <span class="cddto">159</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=404364">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">152</span> → <span class="cddto">176</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419744.1">XM_047419744.1</a> → <a href="/protein/XP_047275700.1">XP_047275700.1</a> DNA-binding protein Ikaros isoform X24</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419735.1">XM_047419735.1</a> → <a href="/protein/XP_047275691.1">XP_047275691.1</a> DNA-binding protein Ikaros isoform X18</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011515065.3">XM_011515065.3</a> → <a href="/protein/XP_011513367.1">XP_011513367.1</a> DNA-binding protein Ikaros isoform X5</p>
|
||
<p>
|
||
<a href="/ipg/XP_011513367.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for XP_011513367.1</a>
|
||
</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TNQ0" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TNQ0</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011513367.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">139</span> → <span class="cddto">159</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=404364">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">152</span> → <span class="cddto">176</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419724.1">XM_047419724.1</a> → <a href="/protein/XP_047275680.1">XP_047275680.1</a> DNA-binding protein Ikaros isoform X7</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419730.1">XM_047419730.1</a> → <a href="/protein/XP_047275686.1">XP_047275686.1</a> DNA-binding protein Ikaros isoform X13</p>
|
||
<dl>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_047275686.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">139</span> → <span class="cddto">159</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=433230">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">152</span> → <span class="cddto">176</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419732.1">XM_047419732.1</a> → <a href="/protein/XP_047275688.1">XP_047275688.1</a> DNA-binding protein Ikaros isoform X15</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419740.1">XM_047419740.1</a> → <a href="/protein/XP_047275696.1">XP_047275696.1</a> DNA-binding protein Ikaros isoform X21</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A2R8YFR0" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A2R8YFR0</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000496655.2" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENSP00000496655.2</a>, <a href="http://www.ensembl.org/id/ENST00000642219.2" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENST00000642219.2</a></dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419725.1">XM_047419725.1</a> → <a href="/protein/XP_047275681.1">XP_047275681.1</a> DNA-binding protein Ikaros isoform X9</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A4D260" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A4D260</a>, <a href="https://www.uniprot.org/uniprot/B4E0Z1" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">B4E0Z1</a>, <a href="https://www.uniprot.org/uniprot/D3DVM5" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">D3DVM5</a>, <a href="https://www.uniprot.org/uniprot/O00598" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">O00598</a>, <a href="https://www.uniprot.org/uniprot/Q13422" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q13422</a>, <a href="https://www.uniprot.org/uniprot/Q53XL2" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q53XL2</a>, <a href="https://www.uniprot.org/uniprot/Q69BM4" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q69BM4</a>, <a href="https://www.uniprot.org/uniprot/Q8WVA3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q8WVA3</a></dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419728.1">XM_047419728.1</a> → <a href="/protein/XP_047275684.1">XP_047275684.1</a> DNA-binding protein Ikaros isoform X11</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419733.1">XM_047419733.1</a> → <a href="/protein/XP_047275689.1">XP_047275689.1</a> DNA-binding protein Ikaros isoform X16</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419738.1">XM_047419738.1</a> → <a href="/protein/XP_047275694.1">XP_047275694.1</a> DNA-binding protein Ikaros isoform X18</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_017011668.2">XM_017011668.2</a> → <a href="/protein/XP_016867157.1">XP_016867157.1</a> DNA-binding protein Ikaros isoform X25</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/Q13422" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q13422</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_016867157.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227381">COG5048</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">1</span> → <span class="cddto">131</span></dt>
|
||
<dd class="clearfix"> COG5048; FOG: Zn-finger [General function prediction only]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">60</span> → <span class="cddto">80</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419746.1">XM_047419746.1</a> → <a href="/protein/XP_047275702.1">XP_047275702.1</a> DNA-binding protein Ikaros isoform X26</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TMF3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TMF3</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419750.1">XM_047419750.1</a> → <a href="/protein/XP_047275706.1">XP_047275706.1</a> DNA-binding protein Ikaros isoform X31</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TMF3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TMF3</a>
|
||
</dd>
|
||
<dt>Related</dt>
|
||
<dd><a href="http://www.ensembl.org/id/ENSP00000513804.1" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENSP00000513804.1</a>, <a href="http://www.ensembl.org/id/ENST00000698573.1" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">ENST00000698573.1</a></dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011515062.3">XM_011515062.3</a> → <a href="/protein/XP_011513364.1">XP_011513364.1</a> DNA-binding protein Ikaros isoform X5</p>
|
||
<p>
|
||
<a href="/ipg/XP_011513364.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for XP_011513364.1</a>
|
||
</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TNQ0" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TNQ0</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011513364.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">139</span> → <span class="cddto">159</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=404364">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">152</span> → <span class="cddto">176</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011515073.3">XM_011515073.3</a> → <a href="/protein/XP_011513375.1">XP_011513375.1</a> DNA-binding protein Ikaros isoform X21</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A2R8YFR0" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A2R8YFR0</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (3) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011513375.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">80</span> → <span class="cddto">100</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=395048">pfam00096</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">78</span> → <span class="cddto">100</span></dt>
|
||
<dd class="clearfix"> zf-C2H2; Zinc finger, C2H2 type</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=404364">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">92</span> → <span class="cddto">117</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419748.1">XM_047419748.1</a> → <a href="/protein/XP_047275704.1">XP_047275704.1</a> DNA-binding protein Ikaros isoform X28</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TMF3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TMF3</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011515064.4">XM_011515064.4</a> → <a href="/protein/XP_011513366.1">XP_011513366.1</a> DNA-binding protein Ikaros isoform X5</p>
|
||
<p>
|
||
<a href="/ipg/XP_011513366.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for XP_011513366.1</a>
|
||
</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TNQ0" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TNQ0</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011513366.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">139</span> → <span class="cddto">159</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=404364">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">152</span> → <span class="cddto">176</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_011515060.3">XM_011515060.3</a> → <a href="/protein/XP_011513362.1">XP_011513362.1</a> DNA-binding protein Ikaros isoform X3</p>
|
||
<p>
|
||
<a href="/ipg/XP_011513362.1/" ref="ncbi_uid=10320">See identical proteins and their annotated locations for XP_011513362.1</a>
|
||
</p>
|
||
<dl>
|
||
<dt class="clear"> Conserved Domains (2) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_011513362.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">149</span> → <span class="cddto">169</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=372612">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">162</span> → <span class="cddto">186</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419749.1">XM_047419749.1</a> → <a href="/protein/XP_047275705.1">XP_047275705.1</a> DNA-binding protein Ikaros isoform X30</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TMF3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TMF3</a>
|
||
</dd>
|
||
<dt class="clear"> Conserved Domains (4) <a href="/Structure/cdd/wrpsb.cgi?seqinput=XP_047275705.1">summary</a></dt>
|
||
<dd>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=227381">COG5048</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">2</span> → <span class="cddto">122</span></dt>
|
||
<dd class="clearfix"> COG5048; FOG: Zn-finger [General function prediction only]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=275368">sd00017</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">70</span> → <span class="cddto">90</span></dt>
|
||
<dd class="clearfix"> ZF_C2H2; C2H2 Zn finger [structural motif]</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=395048">pfam00096</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">68</span> → <span class="cddto">90</span></dt>
|
||
<dd class="clearfix"> zf-C2H2; Zinc finger, C2H2 type</dd>
|
||
</dl>
|
||
<dl class="level2">
|
||
<dt><a href="/Structure/cdd/cddsrv.cgi?uid=433230">pfam13465</a><br /><span class="cddlocation">Location:</span><span class="cddfrom">82</span> → <span class="cddto">107</span></dt>
|
||
<dd class="clearfix"> zf-H2C2_2; Zinc-finger double domain</dd>
|
||
</dl>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419741.1">XM_047419741.1</a> → <a href="/protein/XP_047275697.1">XP_047275697.1</a> DNA-binding protein Ikaros isoform X22</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419742.1">XM_047419742.1</a> → <a href="/protein/XP_047275698.1">XP_047275698.1</a> DNA-binding protein Ikaros isoform X22</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_047419743.1">XM_047419743.1</a> → <a href="/protein/XP_047275699.1">XP_047275699.1</a> DNA-binding protein Ikaros isoform X22</p>
|
||
<dl></dl>
|
||
</li>
|
||
</ol>
|
||
<h3 id="refseq-sequencedescription-p115832336">Alternate T2T-CHM13v2.0</h3>
|
||
<h4 id="genomic-p115832336">Genomic </h4>
|
||
<ol>
|
||
<li>
|
||
<p>NC_060931.1 Alternate T2T-CHM13v2.0</p>
|
||
<dl>
|
||
<dt>Range</dt>
|
||
<dd class="rs-range">
|
||
<span>50464429..50566317</span>
|
||
</dd>
|
||
<dt>Download</dt>
|
||
<dd><a href="/nuccore/NC_060931.1?from=50464429&to=50566317&report=genbank" ref="ordinalpos=1&ncbi_uid=10320&link_uid=NC_060931.1?from=50464429&to=50566317&report=genbank">GenBank</a>, <a href="/nuccore/NC_060931.1?from=50464429&to=50566317&report=fasta" ref="ordinalpos=1&ncbi_uid=10320&link_uid=NC_060931.1?from=50464429&to=50566317&report=fasta">FASTA</a>, <a href="/nuccore/NC_060931.1?from=50449145&to=50581599&report=graph&content=5" ref="ordinalpos=1&ncbi_uid=10320&link_uid=NC_060931.1?from=50449145&to=50581599&report=graph&content=5">Sequence Viewer (Graphics)</a></dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
<h4 id="mrnaandproteins-p126506736">mRNA and Protein(s) </h4>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357028.1">XM_054357028.1</a> → <a href="/protein/XP_054213003.1">XP_054213003.1</a> DNA-binding protein Ikaros isoform X20</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357009.1">XM_054357009.1</a> → <a href="/protein/XP_054212984.1">XP_054212984.1</a> DNA-binding protein Ikaros isoform X6</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357041.1">XM_054357041.1</a> → <a href="/protein/XP_054213016.1">XP_054213016.1</a> DNA-binding protein Ikaros isoform X29</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TMF3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TMF3</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357014.1">XM_054357014.1</a> → <a href="/protein/XP_054212989.1">XP_054212989.1</a> DNA-binding protein Ikaros isoform X10</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357027.1">XM_054357027.1</a> → <a href="/protein/XP_054213002.1">XP_054213002.1</a> DNA-binding protein Ikaros isoform X19</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357019.1">XM_054357019.1</a> → <a href="/protein/XP_054212994.1">XP_054212994.1</a> DNA-binding protein Ikaros isoform X14</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357011.1">XM_054357011.1</a> → <a href="/protein/XP_054212986.1">XP_054212986.1</a> DNA-binding protein Ikaros isoform X13</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357039.1">XM_054357039.1</a> → <a href="/protein/XP_054213014.1">XP_054213014.1</a> DNA-binding protein Ikaros isoform X32</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TMF3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TMF3</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357002.1">XM_054357002.1</a> → <a href="/protein/XP_054212977.1">XP_054212977.1</a> DNA-binding protein Ikaros isoform X7</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357033.1">XM_054357033.1</a> → <a href="/protein/XP_054213008.1">XP_054213008.1</a> DNA-binding protein Ikaros isoform X26</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TMF3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TMF3</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357017.1">XM_054357017.1</a> → <a href="/protein/XP_054212992.1">XP_054212992.1</a> DNA-binding protein Ikaros isoform X16</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357023.1">XM_054357023.1</a> → <a href="/protein/XP_054212998.1">XP_054212998.1</a> DNA-binding protein Ikaros isoform X21</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A2R8YFR0" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A2R8YFR0</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357001.1">XM_054357001.1</a> → <a href="/protein/XP_054212976.1">XP_054212976.1</a> DNA-binding protein Ikaros isoform X5</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TNQ0" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TNQ0</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357004.1">XM_054357004.1</a> → <a href="/protein/XP_054212979.1">XP_054212979.1</a> DNA-binding protein Ikaros isoform X9</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A4D260" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A4D260</a>, <a href="https://www.uniprot.org/uniprot/B4E0Z1" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">B4E0Z1</a>, <a href="https://www.uniprot.org/uniprot/D3DVM5" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">D3DVM5</a>, <a href="https://www.uniprot.org/uniprot/O00598" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">O00598</a>, <a href="https://www.uniprot.org/uniprot/Q13422" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q13422</a>, <a href="https://www.uniprot.org/uniprot/Q53XL2" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q53XL2</a>, <a href="https://www.uniprot.org/uniprot/Q69BM4" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q69BM4</a>, <a href="https://www.uniprot.org/uniprot/Q8WVA3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q8WVA3</a></dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357005.1">XM_054357005.1</a> → <a href="/protein/XP_054212980.1">XP_054212980.1</a> DNA-binding protein Ikaros isoform X5</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TNQ0" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TNQ0</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357010.1">XM_054357010.1</a> → <a href="/protein/XP_054212985.1">XP_054212985.1</a> DNA-binding protein Ikaros isoform X7</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357018.1">XM_054357018.1</a> → <a href="/protein/XP_054212993.1">XP_054212993.1</a> DNA-binding protein Ikaros isoform X13</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357020.1">XM_054357020.1</a> → <a href="/protein/XP_054212995.1">XP_054212995.1</a> DNA-binding protein Ikaros isoform X15</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357029.1">XM_054357029.1</a> → <a href="/protein/XP_054213004.1">XP_054213004.1</a> DNA-binding protein Ikaros isoform X21</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A2R8YFR0" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A2R8YFR0</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357012.1">XM_054357012.1</a> → <a href="/protein/XP_054212987.1">XP_054212987.1</a> DNA-binding protein Ikaros isoform X9</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A4D260" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A4D260</a>, <a href="https://www.uniprot.org/uniprot/B4E0Z1" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">B4E0Z1</a>, <a href="https://www.uniprot.org/uniprot/D3DVM5" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">D3DVM5</a>, <a href="https://www.uniprot.org/uniprot/O00598" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">O00598</a>, <a href="https://www.uniprot.org/uniprot/Q13422" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q13422</a>, <a href="https://www.uniprot.org/uniprot/Q53XL2" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q53XL2</a>, <a href="https://www.uniprot.org/uniprot/Q69BM4" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q69BM4</a>, <a href="https://www.uniprot.org/uniprot/Q8WVA3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q8WVA3</a></dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357015.1">XM_054357015.1</a> → <a href="/protein/XP_054212990.1">XP_054212990.1</a> DNA-binding protein Ikaros isoform X11</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357021.1">XM_054357021.1</a> → <a href="/protein/XP_054212996.1">XP_054212996.1</a> DNA-binding protein Ikaros isoform X16</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357026.1">XM_054357026.1</a> → <a href="/protein/XP_054213001.1">XP_054213001.1</a> DNA-binding protein Ikaros isoform X18</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357035.1">XM_054357035.1</a> → <a href="/protein/XP_054213010.1">XP_054213010.1</a> DNA-binding protein Ikaros isoform X25</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357037.1">XM_054357037.1</a> → <a href="/protein/XP_054213012.1">XP_054213012.1</a> DNA-binding protein Ikaros isoform X26</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TMF3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TMF3</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357043.1">XM_054357043.1</a> → <a href="/protein/XP_054213018.1">XP_054213018.1</a> DNA-binding protein Ikaros isoform X31</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TMF3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TMF3</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357025.1">XM_054357025.1</a> → <a href="/protein/XP_054213000.1">XP_054213000.1</a> DNA-binding protein Ikaros isoform X18</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357024.1">XM_054357024.1</a> → <a href="/protein/XP_054212999.1">XP_054212999.1</a> DNA-binding protein Ikaros isoform X18</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357034.1">XM_054357034.1</a> → <a href="/protein/XP_054213009.1">XP_054213009.1</a> DNA-binding protein Ikaros isoform X24</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357038.1">XM_054357038.1</a> → <a href="/protein/XP_054213013.1">XP_054213013.1</a> DNA-binding protein Ikaros isoform X26</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TMF3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TMF3</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357016.1">XM_054357016.1</a> → <a href="/protein/XP_054212991.1">XP_054212991.1</a> DNA-binding protein Ikaros isoform X11</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357022.1">XM_054357022.1</a> → <a href="/protein/XP_054212997.1">XP_054212997.1</a> DNA-binding protein Ikaros isoform X16</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357008.1">XM_054357008.1</a> → <a href="/protein/XP_054212983.1">XP_054212983.1</a> DNA-binding protein Ikaros isoform X5</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TNQ0" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TNQ0</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357036.1">XM_054357036.1</a> → <a href="/protein/XP_054213011.1">XP_054213011.1</a> DNA-binding protein Ikaros isoform X25</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357013.1">XM_054357013.1</a> → <a href="/protein/XP_054212988.1">XP_054212988.1</a> DNA-binding protein Ikaros isoform X9</p>
|
||
<dl>
|
||
<dt>UniProtKB/Swiss-Prot</dt>
|
||
<dd><a href="https://www.uniprot.org/uniprot/A4D260" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A4D260</a>, <a href="https://www.uniprot.org/uniprot/B4E0Z1" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">B4E0Z1</a>, <a href="https://www.uniprot.org/uniprot/D3DVM5" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">D3DVM5</a>, <a href="https://www.uniprot.org/uniprot/O00598" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">O00598</a>, <a href="https://www.uniprot.org/uniprot/Q13422" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q13422</a>, <a href="https://www.uniprot.org/uniprot/Q53XL2" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q53XL2</a>, <a href="https://www.uniprot.org/uniprot/Q69BM4" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q69BM4</a>, <a href="https://www.uniprot.org/uniprot/Q8WVA3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">Q8WVA3</a></dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357006.1">XM_054357006.1</a> → <a href="/protein/XP_054212981.1">XP_054212981.1</a> DNA-binding protein Ikaros isoform X5</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TNQ0" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TNQ0</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357030.1">XM_054357030.1</a> → <a href="/protein/XP_054213005.1">XP_054213005.1</a> DNA-binding protein Ikaros isoform X21</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A2R8YFR0" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A2R8YFR0</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357040.1">XM_054357040.1</a> → <a href="/protein/XP_054213015.1">XP_054213015.1</a> DNA-binding protein Ikaros isoform X28</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TMF3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TMF3</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357007.1">XM_054357007.1</a> → <a href="/protein/XP_054212982.1">XP_054212982.1</a> DNA-binding protein Ikaros isoform X5</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TNQ0" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TNQ0</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357003.1">XM_054357003.1</a> → <a href="/protein/XP_054212978.1">XP_054212978.1</a> DNA-binding protein Ikaros isoform X3</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357042.1">XM_054357042.1</a> → <a href="/protein/XP_054213017.1">XP_054213017.1</a> DNA-binding protein Ikaros isoform X30</p>
|
||
<dl>
|
||
<dt>UniProtKB/TrEMBL</dt>
|
||
<dd>
|
||
<a href="https://www.uniprot.org/uniprot/A0A8V8TMF3" ref="itool=Gene_FullReport&PrId=5380&uid=10320&nlmid=&db=gene">A0A8V8TMF3</a>
|
||
</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357031.1">XM_054357031.1</a> → <a href="/protein/XP_054213006.1">XP_054213006.1</a> DNA-binding protein Ikaros isoform X22</p>
|
||
<dl></dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/XM_054357032.1">XM_054357032.1</a> → <a href="/protein/XP_054213007.1">XP_054213007.1</a> DNA-binding protein Ikaros isoform X22</p>
|
||
<dl></dl>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
<h3 class="genomerefseqs gene_std_toggler">
|
||
<a class="jig-ncbitoggler">Suppressed Reference Sequence(s)</a>
|
||
</h3>
|
||
<div class="genomerefseqs_slave">
|
||
<p class="desc"> The following Reference Sequences have been suppressed. <a href="#expl-suppressed-desc" id="expl-suppressed">Explain</a></p>
|
||
<p id="expl-suppressed-desc" style="display:none">These RefSeqs were suppressed for the
|
||
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
|
||
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
|
||
their accession.version below.</p>
|
||
<ol>
|
||
<li>
|
||
<p><a href="/nuccore/334085210">NM_001220766.1</a>: Suppressed sequence</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>NM_001220766.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/334085216">NM_001220769.1</a>: Suppressed sequence</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>NM_001220769.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/334085222">NM_001220772.1</a>: Suppressed sequence</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>NM_001220772.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/334085224">NM_001220773.1</a>: Suppressed sequence</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>NM_001220773.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/334085226">NM_001220774.1</a>: Suppressed sequence</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>NM_001220774.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/334085228">NM_001220775.1</a>: Suppressed sequence</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>NM_001220775.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.</dd>
|
||
</dl>
|
||
</li>
|
||
<li>
|
||
<p><a href="/nuccore/334085230">NM_001220776.1</a>: Suppressed sequence</p>
|
||
<dl>
|
||
<dt>Description</dt>
|
||
<dd>NM_001220776.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.</dd>
|
||
</dl>
|
||
</li>
|
||
</ol>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-related-sequences">
|
||
<section class="rprt-section-header" id="related-sequences">
|
||
<h2 id="header-related-sequences">
|
||
<a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-related-sequences .rprt-section-body'">
|
||
<span class="ui-ncbitoggler-master-text">Related sequences</span>
|
||
</a>
|
||
</h2>
|
||
<div class="rprt-section-tools">
|
||
<a href="#top" title="Go to the top of the page" class="gene-top-page">
|
||
<span>Go to the top of the page</span>
|
||
</a>
|
||
<a href="/books/NBK3841/#EntrezGene.Related_Sequences" title="Help" class="gene-section-help">
|
||
<span>Help</span>
|
||
</a>
|
||
</div>
|
||
</section>
|
||
<div class="rprt-section-body">
|
||
<div>
|
||
<table id="proteinTblId" class="jig-ncbiservergrid" data-jigconfig="webservice:'/gene/10320/data/related-sequences/',webserviceParams: 'p$l=Ajax', isServersideLoad:true, isServersidePaging: true,isServersidePagingCached: true,pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th colspan="2" id="rs-nucleo">Nucleotide</th>
|
||
<th rowspan="2" id="rs-protein">Protein</th>
|
||
</tr>
|
||
<tr>
|
||
<th id="rs-heading">Heading</th>
|
||
<th id="rs-heading-acc">Accession and Version</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody></tbody>
|
||
</table>
|
||
<table id="proteinTblId" class="jig-ncbigrid" data-jigconfig="isPageable:true, pageSize:25">
|
||
<thead>
|
||
<tr>
|
||
<th class="proteinTblTh" rowspan="2" id="rs-prot-acc">Protein Accession</th>
|
||
<th class="proteinTblTh" colspan="2" id="rs-link">Links</th>
|
||
</tr>
|
||
<tr>
|
||
<th id="rs-genepept">GenPept Link</th>
|
||
<th id="rs-uniprot">UniProtKB Link</th>
|
||
</tr>
|
||
</thead>
|
||
<tbody>
|
||
<tr>
|
||
<td headers="rs-prot-acc">Q13422.1</td>
|
||
<td headers="rs-link rs-genepept">
|
||
<a href="/protein/3913926" ref="ordinalpos=1&ncbi_uid=10320&link_uid=3913926">GenPept</a>
|
||
</td>
|
||
<td>
|
||
<a href="https://www.uniprot.org/uniprot/Q13422">UniProtKB/Swiss-Prot:Q13422</a>
|
||
</td>
|
||
</tr>
|
||
</tbody>
|
||
</table>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
<div class="rprt-section gene-additional-links">
|
||
|
||
<section class="rprt-section-header" id="additional-links"><h2 id="header-additional-links"><a href="#" class="jig-ncbitoggler-open" data-jigconfig="targets: '.gene-additional-links .rprt-section-body'"><span class="ui-ncbitoggler-master-text">Additional links</span></a></h2><div class="rprt-section-tools"><a href="#top" title="Go to the top of the page" class="gene-top-page"><span>Go to the top of the page</span></a><a href="/books/NBK3841/#EntrezGene.Additional_Links" title="Help" class="gene-section-help"><span>Help</span></a></div></section>
|
||
|
||
<div class="rprt-section-body" style="">
|
||
|
||
|
||
<h3 class="withnote" id="genelinkout">
|
||
<a class="jig-ncbitoggler">Gene LinkOut</a>
|
||
</h3><div>
|
||
<p>The following <a href="https://www.ncbi.nlm.nih.gov/projects/linkout/index.html">LinkOut</a> resources are supplied by external providers. These providers are responsible for maintaining the links. </p>
|
||
<div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Chemical Information</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Interologous Interaction Database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://ophid.utoronto.ca/redirect/ncbi/human?proteins=10320" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=7911">
|
||
<span>Interologous Interaction Database</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>MilliporeSigma</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.sigmaaldrich.com/catalog/genes/IKZF1?lang=en&region=US" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=9978">
|
||
<span>Ikzf1 products</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Molecular Biology Databases</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>Bgee database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.bgee.org/gene/ENSG00000185811" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=10418">
|
||
<span>IKZF1 gene expression</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>BioGPS</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://biogps.org/gene/10320/" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=5059">
|
||
<span>BioGPS</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>BioGRID Open Repository of CRISPR Screens (ORCS)</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://orcs.thebiogrid.org/Gene/10320" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=10164">
|
||
<span>BioGRID CRISPR Screen Phenotypes (49 hits/1420 screens)</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>CTD: Comparative Toxicogenomics Database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://ctdbase.org/detail.go?type=gene&acc=10320" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=7845">
|
||
<span>CTD: Comparative Toxicogenomics Database - IKZF1</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Domain Mapping of Disease Mutations</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://bioinf.umbc.edu/DMDM/gene_prot_page.php?id=10320" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=7642">
|
||
<span>IKZF1</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Eukaryotic Promoter Database</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://epd.vital-it.ch/cgi-bin/get_doc?db=hgEpdNew&format=genome&entry=IKZF1_1" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=9624">
|
||
<span>IKZF1_1</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>GlyGen glycoinformatics resource</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://glygen.org/protein/Q13422" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=10227">
|
||
<span>GlyGen glycoinformatics resource</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Human eFP Browser</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Circulatory_Respiratory&modeInput=Absolute&primaryGene=10320" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Nervous&modeInput=Absolute&primaryGene=10320" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="http://bar.utoronto.ca/efp_human/cgi-bin/efpWeb.cgi?dataSource=Reproductive&modeInput=Absolute&primaryGene=10320" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=8875">
|
||
<span>Human eFP Browser</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li>Ingenuity Pathways Analysis</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://partnersolution.ingenuity.com/?cid=97ae3f91eab87a&p1=Entrez&p2=GV&s=&ipaUri=%2Fpa%2Fapi%2Fv2%2Fgeneview%3Fapplicationname%3DEntrez%26geneId%3D10320%26geneidtype%3Dentrezgene" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=5628">
|
||
<span>Ingenuity Pathways Analysis</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>InnateDB</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.innatedb.com/getGeneCard.do?id=16397" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=7894">
|
||
<span>InnateDB</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>InterMine</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.humanmine.org/humanmine/search?keyword=ENSG00000185811" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=9169">
|
||
<span>InterMine</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>Kyoto Encyclopedia of Genes and Genomes</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.genome.jp/dbget-bin/www_bget?hsa:10320" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=5174">
|
||
<span>Kyoto Encyclopedia of Genes and Genomes</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>OMA Browser: Orthologous MAtrix</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN88950/" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN88960/" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://omabrowser.org/oma/info/HUMAN88948/" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=9822">
|
||
<span>OMA Browser: Orthologous MAtrix</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>OrthoDB catalog of orthologs</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.orthodb.org/?ncbi=10320" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=8178">
|
||
<span>Orthologs</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>PhosphoSitePlus</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.phosphosite.org/entrezGeneIdAction.action?id=10320" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=7987">
|
||
<span>PhosphoSitePlus® - comprehensive post-translational modification resource</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>The Gene Wiki</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://en.wikipedia.org/wiki/IKZF1" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=6933">
|
||
<span>The Gene Wiki</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="free-rsc"></span>The Weizmann Institute of Science GeneCards and MalaCards databases</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=IKZF1" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=8598">
|
||
<span>GeneCard for IKZF1</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Research Materials</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="order-rsc"></span>Addgene Non-profit plasmid repository</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://addgene.org//browse/gene/10320" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=5304">
|
||
<span>Get Plasmids - Addgene</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>Bio-Techne</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/ikaros/antibodies?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=antibodies" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>Ikaros/IKZF1 Antibodies</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/ikaros/lysates?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=lysates" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>Ikaros/IKZF1 Lysates</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.bio-techne.com/t/ikaros/proteins-enzymes?utm_source=linkout&utm_medium=referral&utm_campaign=product&utm_term=proteins" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=8242">
|
||
<span>Ikaros/IKZF1 Proteins</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li>ExactAntigen/Labome</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.labome.com/review/gene/human/IKZF1-antibody.html" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=5753">
|
||
<span>reagent review</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.labome.com/gene/human/IKZF1-antibody.html" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=5753">
|
||
<span>reagents</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GenScript latest version of gene cDNA ORF Clone</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.genscript.com/gene/10320" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=8012">
|
||
<span>GenScript latest version of gene cDNA ORF Clone</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GeneCopoeia Inc.</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=22&field=5&key=10320" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order promoter clone</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=11&field=5&key=10320" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order shRNA clones</span>
|
||
</a>
|
||
</li>
|
||
<li>
|
||
<a target="_blank" href="https://www.genecopoeia.com/product/search/result.php?prt=1&field=5&key=10320" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=7255">
|
||
<span>Order full-length ORF clone</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>GeneTex Inc</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.genetex.com/Product/Search?geneid=10320&type=01&page=1" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=8117">
|
||
<span>Find Quality Antibodies</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>Kazusa DNA Research Institute</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://www.kazusa.or.jp/kop/dsearch/symsearch.cgi?keyword=IKZF1;" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=3267">
|
||
<span>Kazusa DNA Research Institute</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
<li><span class="order-rsc"></span>OriGene</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="https://www.origene.com/search?q=Ikzf1" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=7994">
|
||
<span>Order Ikzf1 cDNA clone/Protein/Antibody/RNAi</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
<div class="linkout">
|
||
<a class="jig-ncbitoggler-open main">
|
||
<span>Tools</span>
|
||
</a>
|
||
<ul>
|
||
<li><span class="free-rsc"></span>GeneMANIA</li>
|
||
<ul>
|
||
<li>
|
||
<a target="_blank" href="http://genemania.org/link?o=9606&g=10320" ref="itool=Gene_FullReport&uid=10320&nlmid=&db=gene&log$=linkoutlink&PrId=7529">
|
||
<span>GeneMANIA</span>
|
||
</a>
|
||
</li>
|
||
</ul>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="urls-in-genombrowser" style="display:none">
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div><input type="hidden" class="section_status_input" name="status_checked" id="status_checked" value="" /><input type="hidden" class="section_status_input" name="status_open" id="status_open" value="summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links" /><input type="hidden" class="section_status_input" name="status_exist" id="status_exist" value="summary,context,region,expression,bibliography,phenotypes,variation,hiv,,interactions,geneInfo,proteinInfo,refSeq,related,links" /><input type="hidden" class="section_status_input" name="status_closed" id="status_closed" value="" /><meta name="status_checked" content="" class="meta_section_status" /><meta name="status_open" content="summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links" class="meta_section_status" /><meta name="status_exist" content="summary,context,region,expression,bibliography,phenotypes,variation,hiv,,interactions,geneInfo,proteinInfo,refSeq,related,links" class="meta_section_status" /><meta name="status_closed" content="" class="meta_section_status" /><script type="text/javascript">
|
||
|
||
var section_status_meta = {
|
||
'status_checked': '',
|
||
'status_open': 'summary,region,context,bibliography,phenotypes,variation,hiv,interactions,pathways,geneInfo,proteinInfo,refSeq,related,links',
|
||
'status_exist': 'summary,context,region,expression,bibliography,phenotypes,variation,hiv,,interactions,geneInfo,proteinInfo,refSeq,related,links',
|
||
'status_closed': ''
|
||
};
|
||
|
||
|
||
/*
|
||
for (var o in section_status_meta) {
|
||
var meta=document.createElement('meta');
|
||
meta.name = o;
|
||
meta.content = section_status_meta[o];
|
||
var attr = document.createAttribute('data-ignore-limit');
|
||
attr.value = 'true';
|
||
meta.setAttributeNode(attr);
|
||
document.getElementsByTagName('head')[0].appendChild(meta);
|
||
}
|
||
*/
|
||
|
||
|
||
var __ncbi_sg_pingCallbacks_render_gene = function (data, evtObj, type) {
|
||
// data looks like {jsevent: "click", "link_id": "foo", ...}
|
||
// evtObj is the JS event object
|
||
// type is either "stat" (for applog) or "ga"
|
||
var extraData = {};
|
||
if (type == "stat") {
|
||
for (var o in section_status_meta) {
|
||
extraData[o] = section_status_meta[o];
|
||
}
|
||
|
||
return extraData;
|
||
|
||
}
|
||
}
|
||
|
||
|
||
</script></div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div id="messagearea_bottom">
|
||
|
||
</div>
|
||
<div class=" bottom">
|
||
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
<div class="supplemental col three_col last" id="sidebar_tabular">
|
||
<!-- sidebar close/hide button-->
|
||
<div class="ui-helper-clearfix">
|
||
<a href="#" id="sidecontent_2_pullout" style="float:right;" class="sidecontentpullout_local collapse_button"><span>Hide sidebar >></span></a>
|
||
</div>
|
||
<!-- end sidebar close/hide button-->
|
||
|
||
<h2 class="offscreen_noflow">Supplemental Content</h2>
|
||
|
||
<div id="gene-sidebar">
|
||
<div>
|
||
<div class="portlet brieflink dis-table-of-contents">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Table of contents</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_TableOfContents" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_TableOfContents.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li class="">
|
||
<a href="#summary">Summary</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#genomic-context">Genomic context</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#genomic-regions-transcripts-products">Genomic regions, transcripts, and products</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#gene-expression">Expression</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#bibliography">Bibliography</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#phenotypes">Phenotypes</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#variation">Variation</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#HIV-1-interactions">HIV-1 interactions</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#pathways">Pathways from PubChem</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#interactions">Interactions</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#general-gene-info">General gene information</a>
|
||
<div class="subsection-links"><a href="#gene-markers">Markers</a>, <a href="#homology">Homology</a>, <a href="#gene-ontology">Gene Ontology</a></div>
|
||
</li>
|
||
<li class="">
|
||
<a href="#general-protein-info">General protein information</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#reference-sequences">NCBI Reference Sequences (RefSeq)</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#related-sequences">Related sequences</a>
|
||
</li>
|
||
<li class="">
|
||
<a href="#additional-links">Additional links</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-genomesbrowser brieflink dis-genomesbrowser">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Genome Browsers</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GenomeBrowsers.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_GenomeBrowsers" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GenomeBrowsers.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="#">Loading...</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet dis-related-info brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related information</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="discovery_db_links" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedInformation.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content DiscoveryDbLinks">
|
||
<ul>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clone/order/gene/10320" ref="log$=recordlinks">Order cDNA clone</a>
|
||
<div class="brieflinkpop offscreen_noflow">Order cDNA clone</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/structure?LinkName=gene_structure&from_uid=10320" ref="log$=recordlinks">3D structures</a>
|
||
<div class="brieflinkpop offscreen_noflow">3D structure of a gene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_alltarget_list&from_uid=10320" ref="log$=recordlinks">BioAssay by Target (List)</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioAssays related to the gene by protein target or RNAi target</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="//pubchem.ncbi.nlm.nih.gov/assay/bioactivity.html?geneid=10320" ref="log$=recordlinks">BioAssay by Target (Summary)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Summarized PubChem Data on the gene, showing the active data by default</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_target&from_uid=10320" ref="log$=recordlinks">BioAssay, by Gene target</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem BioAssays done on the Gene target</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcassay?LinkName=gene_pcassay_rnai&from_uid=10320" ref="log$=recordlinks">BioAssays, RNAi Target, Tested</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioAssays that contain the gene as the target of a RNAi reagent</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/bioproject?LinkName=gene_bioproject&from_uid=10320" ref="log$=recordlinks">BioProjects</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioProjects related to a gene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/biosystems?LinkName=gene_biosystems&from_uid=10320" ref="log$=recordlinks">BioSystems</a>
|
||
<div class="brieflinkpop offscreen_noflow">BioSystems</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/CCDS/CcdsBrowse.cgi?REQUEST=GENEID&DATA=10320" ref="log$=recordlinks">CCDS</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to CCDS</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar&from_uid=10320" ref="log$=recordlinks">ClinVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/cdd?LinkName=gene_cdd&from_uid=10320" ref="log$=recordlinks">Conserved Domains</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related CDD</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/dbvar?LinkName=gene_dbvar&from_uid=10320" ref="log$=recordlinks">dbVar</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link from Gene to dbVar</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc&from_uid=10320" ref="log$=recordlinks">Full text in PMC</a>
|
||
<div class="brieflinkpop offscreen_noflow">PMC links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pmc?LinkName=gene_pmc_nucleotide&from_uid=10320" ref="log$=recordlinks">Full text in PMC_nucleotide</a>
|
||
<div class="brieflinkpop offscreen_noflow">Full text in PubMedCentral identified from shared sequence links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/sparcle?LinkName=gene_sparcle&from_uid=10320" ref="log$=recordlinks">Functional Class</a>
|
||
<div class="brieflinkpop offscreen_noflow">Functional class of the sequence domain architecture</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gap?LinkName=gene_gap&from_uid=10320" ref="log$=recordlinks">GAP</a>
|
||
<div class="brieflinkpop offscreen_noflow">GAP Links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_neighbors&from_uid=10320" ref="log$=recordlinks">Gene neighbors</a>
|
||
<div class="brieflinkpop offscreen_noflow">Overlapping genes and two nearest non-overlapping genes on either side</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gene?LinkName=gene_gene_h3k4me3&from_uid=10320" ref="log$=recordlinks">Genes with a similar H3K4me3 profile</a>
|
||
<div class="brieflinkpop offscreen_noflow">Genes with a similar profile of promoter-activating H3K4me3 modifications across several tissue types</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/genome?LinkName=gene_genome&from_uid=10320" ref="log$=recordlinks">Genome</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Genome</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/geoprofiles?LinkName=gene_geoprofiles&from_uid=10320" ref="log$=recordlinks">GEO Profiles</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related GEO</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/gtr/tests/?term=10320[geneid]" ref="log$=recordlinks">GTR</a>
|
||
<div class="brieflinkpop offscreen_noflow">Tests for this gene in the NIH Genetic Testing Registry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/homologene?LinkName=gene_homologene&from_uid=10320" ref="log$=recordlinks">HomoloGene</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related HomoloGene</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/medgen?LinkName=gene_medgen_diseases&from_uid=10320" ref="log$=recordlinks">MedGen</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related information in MedGen</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore&from_uid=10320" ref="log$=recordlinks">Nucleotide</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related Nucleotide entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/omim?LinkName=gene_omim&from_uid=10320" ref="log$=recordlinks">OMIM</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related OMIM entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/probe?LinkName=gene_probe&from_uid=10320" ref="log$=recordlinks">Probe</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Probe entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein&from_uid=10320" ref="log$=recordlinks">Protein</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related protein entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pccompound?LinkName=gene_pccompound&from_uid=10320" ref="log$=recordlinks">PubChem Compound</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem Compounds</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pcsubstance?LinkName=gene_pcsubstance&from_uid=10320" ref="log$=recordlinks">PubChem Substance</a>
|
||
<div class="brieflinkpop offscreen_noflow">PubChem Substances</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed&from_uid=10320" ref="log$=recordlinks">PubMed</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related PubMed entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_rif&from_uid=10320" ref="log$=recordlinks">PubMed (GeneRIF)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related PubMed article from GeneRIFs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_citedinomim&from_uid=10320" ref="log$=recordlinks">PubMed (OMIM)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Gene links to PubMed derived from omim_pubmed_cited links</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/pubmed?LinkName=gene_pubmed_pmc_nucleotide&from_uid=10320" ref="log$=recordlinks">PubMed(nucleotide/PMC)</a>
|
||
<div class="brieflinkpop offscreen_noflow">Citations in PubMed identified from shared sequence and PMC links.</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/protein?LinkName=gene_protein_refseq&from_uid=10320" ref="log$=recordlinks">RefSeq Proteins</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Protein RefSeqs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore?LinkName=gene_nuccore_refseqrna&from_uid=10320" ref="log$=recordlinks">RefSeq RNAs</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeq RNAs</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/nuccore/676260355?report=graph" ref="log$=recordlinks">RefSeqGene</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to Nucleotide RefSeqGenes</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/clinvar?LinkName=gene_clinvar_specific&from_uid=10320" ref="log$=recordlinks">Related gene-specific medical variations</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related medical variations</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/snp?LinkName=gene_snp&from_uid=10320" ref="log$=recordlinks">SNP</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related SNP records</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/taxonomy?LinkName=gene_taxonomy&from_uid=10320" ref="log$=recordlinks">Taxonomy</a>
|
||
<div class="brieflinkpop offscreen_noflow">Link to related taxonomy entry</div>
|
||
</li>
|
||
<li class="brieflinkpopper">
|
||
<a class="brieflinkpopperctrl" href="/variation/view/?q=10320[geneid]" ref="log$=recordlinks">Variation Viewer</a>
|
||
<div class="brieflinkpop offscreen_noflow">Related Variants</div>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet dis-links-to-other-res brieflink">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Links to other resources</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_LinksTwo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_LinksTwo.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:13176">HGNC</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.ensembl.org/id/ENSG00000185811">Ensembl</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.alliancegenome.org/gene/HGNC:13176">AllianceGenome</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/IEB/Research/Acembly/av.cgi?c=geneid&org=9606&l=10320">AceView</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=human&position=NM_001410879">UCSC</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://genecollections.nci.nih.gov/MGC/?ORG=Hs&LIST=BC018349">MGC</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://phgkb.cdc.gov/PHGKB/huGEPedia.action?firstQuery=IKZF1&geneID=10320&typeOption=gene&which=2&pubOrderType=pubD&typeSubmit=GO&check=y">HuGE Navigator</a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.genome.jp/dbget-bin/www_bget?hsa:10320">KEGG</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-general-info">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>General information</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_GeneralInfo" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_GeneralInfo.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="/pmc/?term=PMC4383897+OR+PMC3013746+OR+PMC1761442+OR+PMC539985">About Gene</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3840">FAQ</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://ftp.ncbi.nlm.nih.gov/gene/">FTP site</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3841/">Help</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK3842/">My NCBI help</a>
|
||
</li>
|
||
<li>
|
||
<a href="/books/NBK21085/">NCBI Handbook</a>
|
||
</li>
|
||
<li>
|
||
<a href="/gene/statistics/">Statistics</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-related-sites">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Related sites</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedSites.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_RelatedSites" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_RelatedSites.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/BLAST">BLAST</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/genome">Genome</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/bioproject">BioProject</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/genome/gdv/">Genome Data Viewer</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/geo">GEO</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/omim">OMIM</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/probe">Probe</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/RefSeq">RefSeq</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-feedback">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Feedback</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Feedback.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_Feedback" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Feedback.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://support.ncbi.nlm.nih.gov/ics/support/ticketnewwizard.asp?style=classic&deptID=28049">Contact Help Desk</a>
|
||
</li>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/RefSeq/update.cgi?geneid=10320&symbol=IKZF1">Submit Correction</a>
|
||
</li>
|
||
<li>
|
||
<a href="/gene/submit-generif?geneId=10320&sym=IKZF1&name=IKAROS family zinc finger 1&org=Homo sapiens">Submit GeneRIF</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="portlet brieflink dis-subscription">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Subscription</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Subscription.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="Gene_Subscription" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.Gene_RVFullReport.Gene_RightColumn.Gene_Subscription.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<ul>
|
||
<li>
|
||
<a href="https://www.ncbi.nlm.nih.gov/mailman/listinfo/refseq-announce">RefSeq</a>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
<!-- <component id="Gene_RVFullReport.Gene_RightColMenuLinks"/>-->
|
||
<div class="portlet">
|
||
<div class="portlet_head">
|
||
<div class="portlet_title">
|
||
<h3>Recent activity</h3>
|
||
</div>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.Shutter" sid="1" href="#" class="portlet_shutter" title="Show/hide content" remembercollapsed="true" pgsec_name="recent_activity" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.Shutter"></a>
|
||
</div>
|
||
<div class="portlet_content">
|
||
<div id="HTDisplay" class="">
|
||
<input name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.Cmd" sid="1" type="hidden" />
|
||
<div class="action">
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory" cmd="ClearHT" href="?cmd=ClearHT&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.ClearHistory">
|
||
Clear
|
||
</a>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" sid="1" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOn" cmd="HTOff" href="?cmd=HTOff&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle">
|
||
Turn Off
|
||
</a>
|
||
<a name="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" sid="2" realname="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle" class="HTOff" cmd="HTOn" href="?cmd=HTOn&" onclick="return false;" id="EntrezSystem2.PEntrez.Gene.Gene_ResultsPanel.HistoryDisplay.HistoryToggle">
|
||
Turn On
|
||
</a>
|
||
</div>
|
||
<ul id="activity">
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67c9f673a68b6b5afcee9005">IKZF1 IKAROS family zinc finger 1 [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">IKZF1 IKAROS family zinc finger 1 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:10320</div></div>
|
||
<div class="tertiary">Gene</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=2" href="/portal/utils/pageresolver.fcgi?recordid=67c9f671b15b832ebc8c9e22">DNA-binding protein Ikaros isoform 1 [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">DNA-binding protein Ikaros isoform 1 [Homo sapiens]<div class="brieflinkpopdesc">gi|5174501|ref|NP_006051.1|</div></div>
|
||
<div class="tertiary">Protein</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=3" href="/portal/utils/pageresolver.fcgi?recordid=67c9f66ea68b6b5afcee705a">IGSF6 immunoglobulin superfamily member 6 [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">IGSF6 immunoglobulin superfamily member 6 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:10261</div></div>
|
||
<div class="tertiary">Gene</div>
|
||
</li>
|
||
<li class="ra_rcd ralinkpopper two_line">
|
||
<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=4" href="/portal/utils/pageresolver.fcgi?recordid=67c9f66ba68b6b5afcee6617">immunoglobulin superfamily member 6 precursor [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">immunoglobulin superfamily member 6 precursor [Homo sapiens]<div class="brieflinkpopdesc">gi|93004094|ref|NP_005840.2|</div></div>
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<div class="tertiary">Protein</div>
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=5" href="/portal/utils/pageresolver.fcgi?recordid=67c9f66aa68b6b5afcee5fcb">IGFBP4 insulin like growth factor binding protein 4 [Homo sapiens]</a>
|
||
<div class="ralinkpop offscreen_noflow">IGFBP4 insulin like growth factor binding protein 4 [Homo sapiens]<div class="brieflinkpopdesc">Gene ID:3487</div></div>
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<div class="tertiary">Gene</div>
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