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606 lines
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117 KiB
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<div class="res_logo"><h1 class="res_name"><a href="/gds">GEO DataSets</a></h1>
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<!-- SearchBar -->
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<div class="search"><div class="search_form"><label for="database" class="offscreen_noflow">Search database</label><select id="database"><optgroup label="Recent"><option value="gds" selected="selected">GEO DataSets</option><option value="pmc">PMC</option><option value="refseq">RefSeq</option><option value="books" class="last">Books</option></optgroup><optgroup label="All"><option value="gquery">All Databases</option><option value="assembly">Assembly</option><option value="biocollections">Biocollections</option><option value="bioproject">BioProject</option><option value="biosample">BioSample</option><option value="books">Books</option><option value="clinvar">ClinVar</option><option value="cdd">Conserved Domains</option><option value="gap">dbGaP</option><option value="dbvar">dbVar</option><option value="gene">Gene</option><option value="genome">Genome</option><option value="gds">GEO DataSets</option><option value="geoprofiles">GEO Profiles</option><option value="gtr">GTR</option><option value="ipg">Identical Protein Groups</option><option value="medgen" data-ac_dict="medgen_disease_name">MedGen</option><option value="mesh" data-ac_dict="mesh_suggestions">MeSH</option><option value="nlmcatalog">NLM Catalog</option><option value="nuccore">Nucleotide</option><option value="omim">OMIM</option><option value="pmc">PMC</option><option value="protein">Protein</option><option value="proteinclusters">Protein Clusters</option><option value="protfam">Protein Family Models</option><option value="pcassay">PubChem BioAssay</option><option value="pccompound">PubChem Compound</option><option value="pcsubstance">PubChem Substance</option><option value="pubmed" data-ac_dict="pm_related_queries_2">PubMed</option><option value="snp">SNP</option><option value="sra">SRA</option><option value="structure">Structure</option><option value="taxonomy">Taxonomy</option><option value="toolkit">ToolKit</option><option value="toolkitall">ToolKitAll</option><option value="toolkitbookgh">ToolKitBookgh</option></optgroup></select><div class="nowrap"><label for="term" class="offscreen_noflow" accesskey="/">Search term</label><div class="nowrap"><input type="text" name="term" id="term" title="Search GEO DataSets" value="(genome binding/occupancy profiling by array[DataSet Type] OR genome binding/occupancy profiling by genome tiling array[DataSet Type] OR genome binding/occupancy profiling by high throughput sequencing[DataSet Type]) AND gse[Entry Type]" class="jig-ncbiclearbutton jig-ncbiautocomplete" data-jigconfig="isEnabled:false,disableUrl:'NcbiSearchBarAutoComplCtrl'" autocomplete="off" data-sbconfig="ds:'no',pjs:'yes',afs:'yes'" /></div><button id="search" type="submit" class="button_search nowrap" cmd="go">Search</button></div></div><ul class="searchlinks inline_list"><set></set><li><a name="SaveSearch" title="Click to create an email alert for this search" href="/sites/myncbi/searches/save?db=gds&qk=481" id="SaveSearch">Create alert</a></li><li><a href="/gds/advanced">Advanced</a></li><li class="help"><a id="help" class="jig-ncbihelpwindow" target="ncbihelp" name="help" href="/geo/info/datasets.html">Help</a></li></ul></div>
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<input name="EntrezSystem2.PEntrez.Gds.Entrez_PageController.PreviousPageName" sid="1" type="hidden" value="results" />
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<div id="faceted_search" class="col two_col">
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<h2 class="offscreen_noflow">Result Filters</h2>
|
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<div class="facet_cont" data-db="gds" data-default_grps="fg_entryTypeGds,fg_organismGds,fg_studyTypeGds,fg_authorGds,fg_attNameGds,fg_pubDatesGds" data-sd="db:'gds',op:'search',term:'(genome%20binding%2Foccupancy%20profiling%20by%20array%5BDataSet%20Type%5D%20OR%20genome%20binding%2Foccupancy%20profiling%20by%20genome%20tiling%20array%5BDataSet%20Type%5D%20OR%20genome%20binding%2Foccupancy%20profiling%20by%20high%20throughput%20sequencing%5BDataSet%20Type%5D)%20AND%20gse%5BEntry%20Type%5D',qk:'481',linkname:'',idsfromresult:'',extra:''"><ul class="facet" data-filter_id="entryTypeGds" id="_entryTypeGds"><li class="filter_grp "><div class="clearfix"><h3>Entry type</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="dataSetsGds">DataSets</a><span class="fcount">(0)</span></li><li class="fil_val"><a href="#" data-value_id="seriesGds">Series</a><span class="fcount">(44,816)</span></li><li class="fil_val"><a href="#" data-value_id="samplesGds">Samples</a><span class="fcount">(0)</span></li><li class="fil_val"><a href="#" data-value_id="platformsGds">Platforms</a><span class="fcount">(0)</span></li></ul></li></ul><ul class="facet" data-filter_id="organismGds" id="_organismGds" data-of="yes"><li class="filter_grp of_grp"><div class="clearfix"><h3>Organism</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="more"><a href="#organismGds_more" data-value_id="fetch_more" data-jigconfig=" hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '300px'">Customize ...</a><div style="display:none;" id="organismGds_more"></div></li></ul></li></ul><ul class="facet" data-filter_id="studyTypeGds" id="_studyTypeGds"><li class="filter_grp "><div class="clearfix"><h3>Study type</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="expProfByArrGds">Expression profiling by array</a></li><li class="fil_val"><a href="#" data-value_id="metProfByArrGds">Methylation profiling by array</a></li><li class="more"><a href="#studyTypeGds_more" data-value_id="fetch_more" data-jigconfig=" hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '300px'">Customize ...</a><div style="display:none;" id="studyTypeGds_more"></div></li></ul></li></ul><ul class="facet" data-filter_id="authorGds" id="_authorGds" data-of="yes"><li class="filter_grp of_grp"><div class="clearfix"><h3>Author</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="more"><a href="#authorGds_more" data-value_id="fetch_more" data-jigconfig=" hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '300px'">Customize ...</a><div style="display:none;" id="authorGds_more"></div></li></ul></li></ul><ul class="facet" data-filter_id="attNameGds" id="_attNameGds" data-of="yes"><li class="filter_grp of_grp"><div class="clearfix"><h3>Attribute name</h3><a href="#" data-value_id="" class="clear clear_hide">Clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="tissueGds">tissue</a><span class="fcount">(11,199)</span></li><li class="fil_val"><a href="#" data-value_id="strainGds">strain</a><span class="fcount">(9,095)</span></li><li class="more"><a href="#attNameGds_more" data-value_id="fetch_more" data-jigconfig=" hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '300px'">Customize ...</a><div style="display:none;" id="attNameGds_more"></div></li></ul></li></ul><ul class="facet" data-filter_id="pubDatesGds" data-ds="yes" id="_pubDatesGds"><li class="filter_grp"><div class="clearfix"><h3>Publication dates</h3><a href="#" data-value_id="" class="clear clear_hide">clear</a></div><ul><li class="fil_val"><a href="#" data-value_id="d30Gds">30 days</a></li><li class="fil_val"><a href="#" data-value_id="y1Gds">1 year</a></li><li class="daterange"><a id="facet_date_rangepubDatesGds" href="#facet_date_range_divpubDatesGds" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'middle left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '375px'">
|
||
Custom range...</a></li><div id="facet_date_range_divpubDatesGds" style="display:none;" class="facets_dialog"><button class="ui-ncbipopper-close-button ui-ncbipopper-close-button-generated ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-blue" generated="true" role="button" aria-disabled="false"><span class="ui-button-text">x</span></button><h4>Custom date range</h4><div><label class="offscreen_noflow" for="facet_date_st_yearpubDatesGds">Start Year</label><input type="text" size="4" placeholder="YYYY" id="facet_date_st_yearpubDatesGds" value="" class="input_date_ym" /><label class="offscreen_noflow" for="facet_date_st_monthpubDatesGds">Start Month</label><input type="text" size="2" placeholder="MM" id="facet_date_st_monthpubDatesGds" value="" class="input_date_ym" /><label class="offscreen_noflow" for="facet_date_st_daypubDatesGds">Start Day</label><input type="text" size="2" placeholder="DD" id="facet_date_st_daypubDatesGds" value="" /><span>to</span><label class="offscreen_noflow" for="facet_date_end_yearpubDatesGds">End Year</label><input type="text" size="4" placeholder="YYYY" id="facet_date_end_yearpubDatesGds" value="" class="input_date_ym" /><label class="offscreen_noflow" for="facet_date_end_monthpubDatesGds">End Month</label><input type="text" size="2" placeholder="MM" id="facet_date_end_monthpubDatesGds" value="" class="input_date_ym" /><label class="offscreen_noflow" for="facet_date_end_daypubDatesGds">End Day</label><input type="text" size="2" placeholder="DD" id="facet_date_end_daypubDatesGds" value="" /></div><div class="actions clearfix"><button class="jig-ncbibutton primary-action btn_date_apply" data-jigconfig="'color': 'ui-ncbibutton-blue'" id="facet_date_range_applypubDatesGds">Apply</button><button class="jig-ncbibutton secondary-action btn_date_clear" data-jigconfig="'color': 'ui-ncbibutton-gray'" id="facet_date_range_clearpubDatesGds">Clear</button></div></div></ul></li></ul><ul class="facet facet_reset"><li><a href="#" data-value_id="reset">Clear all</a></li></ul><ul class="facet_tools"><li><a id="more_filter_groups_link" href="#more_filter_groups" class="jig-ncbipopper" data-jigconfig="triggerPosition: 'middle right', destPosition: 'top left', hasArrow: true, arrowDirection: 'left', closeEvent : 'click', openEvent: 'click', adjustFit: 'autoAdjust', openAnimation: 'none', closeAnimation: 'none', addCloseButton:true, width: '180px'">
|
||
Show additional filters</a></li><div id="more_filter_groups" style="display:none;" class="facets_dialog"><button class="ui-ncbipopper-close-button ui-ncbipopper-close-button-generated ui-state-default ui-corner-all ui-button-text-only ui-ncbibutton ui-ncbibutton-blue" generated="true" role="button" aria-disabled="false"><span class="ui-button-text">x</span></button><h4>Additional filters</h4><ul class="filter_groups_more facet"><li><input type="checkbox" id="fg_entryTypeGds" /><label for="fg_entryTypeGds">Entry type</label></li><li><input type="checkbox" id="fg_organismGds" /><label for="fg_organismGds">Organism</label></li><li><input type="checkbox" id="fg_studyTypeGds" /><label for="fg_studyTypeGds">Study type</label></li><li><input type="checkbox" id="fg_authorGds" /><label for="fg_authorGds">Author</label></li><li><input type="checkbox" id="fg_attNameGds" /><label for="fg_attNameGds">Attribute name</label></li><li><input type="checkbox" id="fg_subVarTypeGds" /><label for="fg_subVarTypeGds">Subset variable type</label></li><li><input type="checkbox" id="fg_pubDatesGds" /><label for="fg_pubDatesGds">Publication dates</label></li><li><input type="checkbox" id="fg_sampleCountGds" /><label for="fg_sampleCountGds">Sample count</label></li><li><input type="checkbox" id="fg_suppFileGds" /><label for="fg_suppFileGds">Supplementary file</label></li><li><input id="fg_field_search" type="checkbox" /><label for="fg_field_search">Search fields</label></li></ul><div class="actions clearfix"><button class="filter_groups_more_apply jig-ncbibutton primary-action" id="filter_groups_apply" data-jigconfig="'color': 'ui-ncbibutton-blue'">Show</button></div></div></ul><input name="EntrezSystem2.PEntrez.Gds.Gds_Facets.FacetsUrlFrag" sid="1" type="hidden" value="filters=" /><input name="EntrezSystem2.PEntrez.Gds.Gds_Facets.FacetSubmitted" sid="1" type="hidden" value="false" /><input name="EntrezSystem2.PEntrez.Gds.Gds_Facets.BMFacets" sid="1" type="hidden" value="" /></div>
|
||
</div>
|
||
<div id="maincontent" class="col seven_col">
|
||
<div class="content">
|
||
<div class="results_settings"><ul class="inline_list left display_settings"><li><a name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_DisplayBar.Display" sid="0" href="#" class="jig-ncbipopper" data-jigconfig="triggerPosition : 'bottom center',destPosition : 'top center',destSelector : '#display_settings_menu_report', hasArrow : false,openEvent : 'click',closeEvent : 'click',isTriggerElementCloseClick: false,addCloseButton : false, groupName: 'entrez_pg'" id="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_DisplayBar.Display">Summary<span href="#" class="tgt_dark"></span></a></li><li><a name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_DisplayBar.Display" sid="0" href="#" class="jig-ncbipopper" data-jigconfig="triggerPosition : 'bottom center',destPosition : 'top center',destSelector : '#display_settings_menu_ps', hasArrow : false,openEvent : 'click',closeEvent : 'click',isTriggerElementCloseClick: false,addCloseButton : false, groupName: 'entrez_pg'" 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jQuery(document).ready( function () {
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jQuery("#send_to_menu input[type='radio']").click( function () {
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var selectedValue = jQuery(this).val().toLowerCase();
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if(selectedDiv.is(":hidden")){
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jQuery("#send_to_menu div.submenu:visible").slideUp();
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selectedDiv.slideDown();
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}
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});
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jQuery("#sendto").bind("ncbipopperclose", function(){
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jQuery("#send_to_menu div.submenu:visible").css("display","none");
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jQuery("#send_to_menu input[type='radio']:checked").attr("checked",false);
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});
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<div><div class="rprt"><div class="rprtnum nohighlight"><label for="UidCheckBox200290658" class="ui-helper-hidden-accessible">Select item 200290658</label><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_RVDocSum.uid" sid="1" type="checkbox" id="UidCheckBox200290658" value="200290658" /><span>1.</span></div><div class="rslt"><div class="rsltcont"><p class="title"><a href="/geo/query/acc.cgi?acc=GSE290658" ref="ordinalpos=1&ncbi_uid=200290658&link_uid=200290658">Molecular fingerprints for bone marrow cells, acute lymphoblastic leukemia [ATAC-seq]</a></p><div class="supp">(Submitter supplied) The overall goal of this study was to characterize bone marrow cells based on their transcriptome, epigenome, surface protein expression and BCR-VDJ-profile for accurate identification of clinically relevant cell states. This submission includes B-cell acute lymphoblastic (pre-)leukemia samples from mice. This project has received funding from ERA perMed JTC2018 under the title „Genomics-based tools for personalized treatment to reduce chemotherapy burden in paediatric cancer” (Acronym “GEPARD”)<dl class="details lefty"><dt>Organism: </dt><dd class="lng_ln">Mus musculus</dd></dl><dl class="details lefty"><dt>Type: </dt><dd class="lng_ln"><b>Genome binding/occupancy profiling by high throughput sequencing</b></dd></dl><dl class="details"><dt>Platform: </dt><dd class="lng_ln"><a href="/geo/query/acc.cgi?acc=GPL24247">GPL24247</a> </dd><dt><a href="/gds/?term=GSE290658[ACCN] AND gsm[ETYP]">6 Samples</a></dt><dd></dd></dl><a href="/geo/download/?acc=GSE290658">Download data: BIGWIG</a></div><div class="aux"><div class="resc"><span class="src">Series</span><dl class="rprtid"><dt>Accession: </dt><dd>GSE290658</dd></dl><dl class="rprtid"><dt>ID:</dt> <dd>200290658</dd> </dl></div><p class="links nohighlight"></p></div></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><label for="UidCheckBox200271687" class="ui-helper-hidden-accessible">Select item 200271687</label><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_RVDocSum.uid" sid="2" type="checkbox" id="UidCheckBox200271687" value="200271687" /><span>2.</span></div><div class="rslt"><div class="rsltcont"><p class="title"><a href="/geo/query/acc.cgi?acc=GSE271687" ref="ordinalpos=2&ncbi_uid=200271687&link_uid=200271687">Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal and malignant urothelial cells</a></p><div class="supp">(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.<dl class="details lefty"><dt>Organism: </dt><dd class="lng_ln">Homo sapiens</dd></dl><dl class="details lefty"><dt>Type: </dt><dd class="lng_ln"><b>Genome binding/occupancy profiling by high throughput sequencing</b>; Expression profiling by high throughput sequencing</dd></dl><dl class="details"><dt>Platform: </dt><dd class="lng_ln"><a href="/geo/query/acc.cgi?acc=GPL24676">GPL24676</a> </dd><dt><a href="/gds/?term=GSE271687[ACCN] AND gsm[ETYP]">38 Samples</a></dt><dd></dd></dl><a href="/geo/download/?acc=GSE271687">Download data: BW, NARROWPEAK</a></div><div class="aux"><div class="resc"><span class="src">Series</span><dl class="rprtid"><dt>Accession: </dt><dd>GSE271687</dd></dl><dl class="rprtid"><dt>ID:</dt> <dd>200271687</dd> </dl></div><p class="links nohighlight"></p></div></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><label for="UidCheckBox200240979" class="ui-helper-hidden-accessible">Select item 200240979</label><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_RVDocSum.uid" sid="3" type="checkbox" id="UidCheckBox200240979" value="200240979" /><span>3.</span></div><div class="rslt"><div class="rsltcont"><p class="title"><a href="/geo/query/acc.cgi?acc=GSE240979" ref="ordinalpos=3&ncbi_uid=200240979&link_uid=200240979">Deciphering the role of IRF4 and its interacting proteins in differentiated regulatory and T helper 17 cells</a></p><div class="supp">(Submitter supplied) The transcription factor interferon regulatory factor 4 (IRF4) is crucial for the differentiation and fate determination of pro-inflammatory Th17 and the functionally opposing group of immunomodulatory regulatory T cells.Despite its central role in Th lineage determination, molecular mechanisms of IRF4-mediated gene expression in fully differentiated Th17/Treg cells are still not fully understood. In the present study, we integrated data derived from affinity-purification and full mass spectrometry-based proteome analysis with chromatin immune precipitation sequencing (ChIP-Seq)to unveil IRF4-driven lineage determination in Treg and Th17 cells.This allowed the characterization of IRF4-steered expression of proteins generally involved in the T cell development as well as subtype-specific differentiation and identification of novel, yet uncharted IRF4 interactors.<a href="/geo/query/acc.cgi?acc=GSE240979"> more...</a><dl class="details lefty"><dt>Organism: </dt><dd class="lng_ln">Mus musculus</dd></dl><dl class="details lefty"><dt>Type: </dt><dd class="lng_ln"><b>Genome binding/occupancy profiling by high throughput sequencing</b></dd></dl><dl class="details"><dt>Platform: </dt><dd class="lng_ln"><a href="/geo/query/acc.cgi?acc=GPL24247">GPL24247</a> </dd><dt><a href="/gds/?term=GSE240979[ACCN] AND gsm[ETYP]">4 Samples</a></dt><dd></dd></dl><a href="/geo/download/?acc=GSE240979">Download data: WIG</a></div><div class="aux"><div class="resc"><span class="src">Series</span><dl class="rprtid"><dt>Accession: </dt><dd>GSE240979</dd></dl><dl class="rprtid"><dt>ID:</dt> <dd>200240979</dd> </dl></div><p class="links nohighlight"></p></div></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><label for="UidCheckBox200198067" class="ui-helper-hidden-accessible">Select item 200198067</label><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_RVDocSum.uid" sid="4" type="checkbox" id="UidCheckBox200198067" value="200198067" /><span>4.</span></div><div class="rslt"><div class="rsltcont"><p class="title"><a href="/geo/query/acc.cgi?acc=GSE198067" ref="ordinalpos=4&ncbi_uid=200198067&link_uid=200198067">Role of Stat6</a></p><div class="supp">(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.<dl class="details lefty"><dt>Organism: </dt><dd class="lng_ln">Mus musculus</dd></dl><dl class="details lefty"><dt>Type: </dt><dd class="lng_ln"><b>Genome binding/occupancy profiling by high throughput sequencing</b>; Expression profiling by high throughput sequencing</dd></dl><dl class="details"><dt>Platform: </dt><dd class="lng_ln"><a href="/geo/query/acc.cgi?acc=GPL13112">GPL13112</a> </dd><dt><a href="/gds/?term=GSE198067[ACCN] AND gsm[ETYP]">23 Samples</a></dt><dd></dd></dl><a href="/geo/download/?acc=GSE198067">Download data</a></div><div class="aux"><div class="resc"><span class="src">Series</span><dl class="rprtid"><dt>Accession: </dt><dd>GSE198067</dd></dl><dl class="rprtid"><dt>ID:</dt> <dd>200198067</dd> </dl></div><p class="links nohighlight"></p></div></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><label for="UidCheckBox200198062" class="ui-helper-hidden-accessible">Select item 200198062</label><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_RVDocSum.uid" sid="5" type="checkbox" id="UidCheckBox200198062" value="200198062" /><span>5.</span></div><div class="rslt"><div class="rsltcont"><p class="title"><a href="/geo/query/acc.cgi?acc=GSE198062" ref="ordinalpos=5&ncbi_uid=200198062&link_uid=200198062">ATACseq of Naïve CD4+ cells from WT, Stat6, and Il21e KO mice</a></p><div class="supp">(Submitter supplied) We report that Stat6-driven gene transcription regulates the transition from Tfh21 to Tfh4 cells, suppressing IL-21 production and promoting IL-4 secretion. We identified a cis-enhancer in the second intron of Il21 as a regulator of Tfh cell cytokine transition, via an effect of Stat6 on chromatin accessibility with repression of Il21 transcription. Chromatin accessibitiy of this second intron region was not affected in the naive CD4+ T cell population<dl class="details lefty"><dt>Organism: </dt><dd class="lng_ln">Mus musculus</dd></dl><dl class="details lefty"><dt>Type: </dt><dd class="lng_ln"><b>Genome binding/occupancy profiling by high throughput sequencing</b></dd></dl><dl class="details"><dt>Platform: </dt><dd class="lng_ln"><a href="/geo/query/acc.cgi?acc=GPL13112">GPL13112</a> </dd><dt><a href="/gds/?term=GSE198062[ACCN] AND gsm[ETYP]">9 Samples</a></dt><dd></dd></dl><a href="/geo/download/?acc=GSE198062">Download data: TXT</a></div><div class="aux"><div class="resc"><span class="src">Series</span><dl class="rprtid"><dt>Accession: </dt><dd>GSE198062</dd></dl><dl class="rprtid"><dt>ID:</dt> <dd>200198062</dd> </dl></div><p class="links nohighlight"></p></div></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><label for="UidCheckBox200198060" class="ui-helper-hidden-accessible">Select item 200198060</label><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_RVDocSum.uid" sid="6" type="checkbox" id="UidCheckBox200198060" value="200198060" /><span>6.</span></div><div class="rslt"><div class="rsltcont"><p class="title"><a href="/geo/query/acc.cgi?acc=GSE198060" ref="ordinalpos=6&ncbi_uid=200198060&link_uid=200198060">ATACseq of WT and Stat6 knockout Tfh21, Tfh214, and Tfh4 cells</a></p><div class="supp">(Submitter supplied) We report that Stat6-driven gene transcription regulates the transition from Tfh21 to Tfh4 cells, suppressing IL-21 production and promoting IL-4 secretion. We identified a cis-enhancer in the second intron of Il21 as a regulator of Tfh cell cytokine transition, via an effect of Stat6 on chromatin accessibility with repression of Il21 transcription. We conclude that Stat6 is necessary for coordinated regulation of IL-21 and IL-4 production by Tfh cells, leading to appropriate maturation of the germinal center B cell response.<dl class="details lefty"><dt>Organism: </dt><dd class="lng_ln">Mus musculus</dd></dl><dl class="details lefty"><dt>Type: </dt><dd class="lng_ln"><b>Genome binding/occupancy profiling by high throughput sequencing</b></dd></dl><dl class="details"><dt>Platform: </dt><dd class="lng_ln"><a href="/geo/query/acc.cgi?acc=GPL13112">GPL13112</a> </dd><dt><a href="/gds/?term=GSE198060[ACCN] AND gsm[ETYP]">6 Samples</a></dt><dd></dd></dl><a href="/geo/download/?acc=GSE198060">Download data: TXT</a></div><div class="aux"><div class="resc"><span class="src">Series</span><dl class="rprtid"><dt>Accession: </dt><dd>GSE198060</dd></dl><dl class="rprtid"><dt>ID:</dt> <dd>200198060</dd> </dl></div><p class="links nohighlight"></p></div></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><label for="UidCheckBox200290788" class="ui-helper-hidden-accessible">Select item 200290788</label><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_RVDocSum.uid" sid="7" type="checkbox" id="UidCheckBox200290788" value="200290788" /><span>7.</span></div><div class="rslt"><div class="rsltcont"><p class="title"><a href="/geo/query/acc.cgi?acc=GSE290788" ref="ordinalpos=7&ncbi_uid=200290788&link_uid=200290788">ChIP-seq data for WAPL in ZFP661 overexpression mESCs</a></p><div class="supp">(Submitter supplied) In this assay, we aimed to investigate the impact of ZFP661 on WAPL binding at CTCF barriers.<dl class="details lefty"><dt>Organism: </dt><dd class="lng_ln">Mus musculus</dd></dl><dl class="details lefty"><dt>Type: </dt><dd class="lng_ln"><b>Genome binding/occupancy profiling by high throughput sequencing</b></dd></dl><dl class="details"><dt>Platform: </dt><dd class="lng_ln"><a href="/geo/query/acc.cgi?acc=GPL24247">GPL24247</a> </dd><dt><a href="/gds/?term=GSE290788[ACCN] AND gsm[ETYP]">8 Samples</a></dt><dd></dd></dl><a href="/geo/download/?acc=GSE290788">Download data: BW, TXT</a></div><div class="aux"><div class="resc"><span class="src">Series</span><dl class="rprtid"><dt>Accession: </dt><dd>GSE290788</dd></dl><dl class="rprtid"><dt>ID:</dt> <dd>200290788</dd> </dl></div><p class="links nohighlight"></p></div></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><label for="UidCheckBox200290787" class="ui-helper-hidden-accessible">Select item 200290787</label><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_RVDocSum.uid" sid="8" type="checkbox" id="UidCheckBox200290787" value="200290787" /><span>8.</span></div><div class="rslt"><div class="rsltcont"><p class="title"><a href="/geo/query/acc.cgi?acc=GSE290787" ref="ordinalpos=8&ncbi_uid=200290787&link_uid=200290787">ATAC-seq in ZFP661 overexpression mESCs</a></p><div class="supp">(Submitter supplied) In this assay, we aimed to investigate the impact of ZFP661 on chromatin accessibility at CTCF barriers.<dl class="details lefty"><dt>Organism: </dt><dd class="lng_ln">Mus musculus</dd></dl><dl class="details lefty"><dt>Type: </dt><dd class="lng_ln"><b>Genome binding/occupancy profiling by high throughput sequencing</b></dd></dl><dl class="details"><dt>Platform: </dt><dd class="lng_ln"><a href="/geo/query/acc.cgi?acc=GPL24247">GPL24247</a> </dd><dt><a href="/gds/?term=GSE290787[ACCN] AND gsm[ETYP]">4 Samples</a></dt><dd></dd></dl><a href="/geo/download/?acc=GSE290787">Download data: BED</a></div><div class="aux"><div class="resc"><span class="src">Series</span><dl class="rprtid"><dt>Accession: </dt><dd>GSE290787</dd></dl><dl class="rprtid"><dt>ID:</dt> <dd>200290787</dd> </dl></div><p class="links nohighlight"></p></div></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><label for="UidCheckBox200284220" class="ui-helper-hidden-accessible">Select item 200284220</label><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_RVDocSum.uid" sid="9" type="checkbox" id="UidCheckBox200284220" value="200284220" /><span>9.</span></div><div class="rslt"><div class="rsltcont"><p class="title"><a href="/geo/query/acc.cgi?acc=GSE284220" ref="ordinalpos=9&ncbi_uid=200284220&link_uid=200284220">Bacterial immunotherapy leveraging IL-10R hysteresis for both phagocytosis evasion and tumor immunity revitalization [CUT&Tag 2]</a></p><div class="supp">(Submitter supplied) Bacterial immunotherapy holds promising cancer-fighting potential. However, unlocking its power requires a mechanistic understanding of how bacteria both evade antimicrobial immune defenses and stimulate antitumor immune responses within the tumor microenvironment (TME). Here, by harnessing an engineered Salmonella enterica strain with this dual proficiency, we unveiled a singular mechanism underlying.<a href="/geo/query/acc.cgi?acc=GSE284220"> more...</a><dl class="details lefty"><dt>Organism: </dt><dd class="lng_ln">Homo sapiens</dd></dl><dl class="details lefty"><dt>Type: </dt><dd class="lng_ln"><b>Genome binding/occupancy profiling by high throughput sequencing</b></dd></dl><dl class="details"><dt>Platform: </dt><dd class="lng_ln"><a href="/geo/query/acc.cgi?acc=GPL24676">GPL24676</a> </dd><dt><a href="/gds/?term=GSE284220[ACCN] AND gsm[ETYP]">24 Samples</a></dt><dd></dd></dl><a href="/geo/download/?acc=GSE284220">Download data: NARROWPEAK</a></div><div class="aux"><div class="resc"><span class="src">Series</span><dl class="rprtid"><dt>Accession: </dt><dd>GSE284220</dd></dl><dl class="rprtid"><dt>ID:</dt> <dd>200284220</dd> </dl></div><p class="links nohighlight"></p></div></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><label for="UidCheckBox200284218" class="ui-helper-hidden-accessible">Select item 200284218</label><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_RVDocSum.uid" sid="10" type="checkbox" id="UidCheckBox200284218" value="200284218" /><span>10.</span></div><div class="rslt"><div class="rsltcont"><p class="title"><a href="/geo/query/acc.cgi?acc=GSE284218" ref="ordinalpos=10&ncbi_uid=200284218&link_uid=200284218">Bacterial immunotherapy leveraging IL-10R hysteresis for both phagocytosis evasion and tumor immunity revitalization [ATAC-seq]</a></p><div class="supp">(Submitter supplied) Bacterial immunotherapy holds promising cancer-fighting potential. However, unlocking its power requires a mechanistic understanding of how bacteria both evade antimicrobial immune defenses and stimulate antitumor immune responses within the tumor microenvironment (TME). Here, by harnessing an engineered Salmonella enterica strain with this dual proficiency, we unveiled a singular mechanism underlying.<a href="/geo/query/acc.cgi?acc=GSE284218"> more...</a><dl class="details lefty"><dt>Organism: </dt><dd class="lng_ln">Homo sapiens</dd></dl><dl class="details lefty"><dt>Type: </dt><dd class="lng_ln"><b>Genome binding/occupancy profiling by high throughput sequencing</b></dd></dl><dl class="details"><dt>Platform: </dt><dd class="lng_ln"><a href="/geo/query/acc.cgi?acc=GPL24676">GPL24676</a> </dd><dt><a href="/gds/?term=GSE284218[ACCN] AND gsm[ETYP]">8 Samples</a></dt><dd></dd></dl><a href="/geo/download/?acc=GSE284218">Download data: NARROWPEAK</a></div><div class="aux"><div class="resc"><span class="src">Series</span><dl class="rprtid"><dt>Accession: </dt><dd>GSE284218</dd></dl><dl class="rprtid"><dt>ID:</dt> <dd>200284218</dd> </dl></div><p class="links nohighlight"></p></div></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><label for="UidCheckBox200283696" class="ui-helper-hidden-accessible">Select item 200283696</label><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_RVDocSum.uid" sid="11" type="checkbox" id="UidCheckBox200283696" value="200283696" /><span>11.</span></div><div class="rslt"><div class="rsltcont"><p class="title"><a href="/geo/query/acc.cgi?acc=GSE283696" ref="ordinalpos=11&ncbi_uid=200283696&link_uid=200283696">Bacterial immunotherapy leveraging IL-10R hysteresis for both phagocytosis evasion and tumor immunity revitalization [CUT&Tag]</a></p><div class="supp">(Submitter supplied) Bacterial immunotherapy holds promising cancer-fighting potential. However, unlocking its power requires a mechanistic understanding of how bacteria both evade antimicrobial immune defenses and stimulate antitumor immune responses within the tumor microenvironment (TME). Here, by harnessing an engineered Salmonella enterica strain with this dual proficiency, we unveiled a singular mechanism underlying.<a href="/geo/query/acc.cgi?acc=GSE283696"> more...</a><dl class="details lefty"><dt>Organism: </dt><dd class="lng_ln">Mus musculus</dd></dl><dl class="details lefty"><dt>Type: </dt><dd class="lng_ln"><b>Genome binding/occupancy profiling by high throughput sequencing</b></dd></dl><dl class="details"><dt>Platform: </dt><dd class="lng_ln"><a href="/geo/query/acc.cgi?acc=GPL24247">GPL24247</a> </dd><dt><a href="/gds/?term=GSE283696[ACCN] AND gsm[ETYP]">33 Samples</a></dt><dd></dd></dl><a href="/geo/download/?acc=GSE283696">Download data: NARROWPEAK</a></div><div class="aux"><div class="resc"><span class="src">Series</span><dl class="rprtid"><dt>Accession: </dt><dd>GSE283696</dd></dl><dl class="rprtid"><dt>ID:</dt> <dd>200283696</dd> </dl></div><p class="links nohighlight"></p></div></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><label for="UidCheckBox200283695" class="ui-helper-hidden-accessible">Select item 200283695</label><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_RVDocSum.uid" sid="12" type="checkbox" id="UidCheckBox200283695" value="200283695" /><span>12.</span></div><div class="rslt"><div class="rsltcont"><p class="title"><a href="/geo/query/acc.cgi?acc=GSE283695" ref="ordinalpos=12&ncbi_uid=200283695&link_uid=200283695">Bacterial immunotherapy leveraging IL-10R hysteresis for both phagocytosis evasion and tumor immunity revitalization [ATACseq]</a></p><div class="supp">(Submitter supplied) Bacterial immunotherapy holds promising cancer-fighting potential. However, unlocking its power requires a mechanistic understanding of how bacteria both evade antimicrobial immune defenses and stimulate antitumor immune responses within the tumor microenvironment (TME). Here, by harnessing an engineered Salmonella enterica strain with this dual proficiency, we unveiled a singular mechanism underlying.<a href="/geo/query/acc.cgi?acc=GSE283695"> more...</a><dl class="details lefty"><dt>Organism: </dt><dd class="lng_ln">Mus musculus</dd></dl><dl class="details lefty"><dt>Type: </dt><dd class="lng_ln"><b>Genome binding/occupancy profiling by high throughput sequencing</b></dd></dl><dl class="details"><dt>Platform: </dt><dd class="lng_ln"><a href="/geo/query/acc.cgi?acc=GPL24247">GPL24247</a> </dd><dt><a href="/gds/?term=GSE283695[ACCN] AND gsm[ETYP]">11 Samples</a></dt><dd></dd></dl><a href="/geo/download/?acc=GSE283695">Download data: NARROWPEAK</a></div><div class="aux"><div class="resc"><span class="src">Series</span><dl class="rprtid"><dt>Accession: </dt><dd>GSE283695</dd></dl><dl class="rprtid"><dt>ID:</dt> <dd>200283695</dd> </dl></div><p class="links nohighlight"></p></div></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><label for="UidCheckBox200263641" class="ui-helper-hidden-accessible">Select item 200263641</label><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_RVDocSum.uid" sid="13" type="checkbox" id="UidCheckBox200263641" value="200263641" /><span>13.</span></div><div class="rslt"><div class="rsltcont"><p class="title"><a href="/geo/query/acc.cgi?acc=GSE263641" ref="ordinalpos=13&ncbi_uid=200263641&link_uid=200263641">CTCF depletion uncouples the role of enhancer-promoter interactions and higher-order chromatin hubs in gene regulation during cellular differentiation.</a></p><div class="supp">(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.<dl class="details lefty"><dt>Organism: </dt><dd class="lng_ln">Homo sapiens</dd></dl><dl class="details lefty"><dt>Type: </dt><dd class="lng_ln">Other; <b>Genome binding/occupancy profiling by high throughput sequencing</b>; Expression profiling by high throughput sequencing</dd></dl><dl class="details"><dt>Platforms: </dt><dd class="lng_ln"><a href="/geo/query/acc.cgi?acc=GPL21697">GPL21697</a> <a href="/geo/query/acc.cgi?acc=GPL30173">GPL30173</a> </dd><dt><a href="/gds/?term=GSE263641[ACCN] AND gsm[ETYP]">137 Samples</a></dt><dd></dd></dl><a href="/geo/download/?acc=GSE263641">Download data: BIGWIG, BW, TXT</a></div><div class="aux"><div class="resc"><span class="src">Series</span><dl class="rprtid"><dt>Accession: </dt><dd>GSE263641</dd></dl><dl class="rprtid"><dt>ID:</dt> <dd>200263641</dd> </dl></div><p class="links nohighlight"></p></div></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><label for="UidCheckBox200263637" class="ui-helper-hidden-accessible">Select item 200263637</label><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_RVDocSum.uid" sid="14" type="checkbox" id="UidCheckBox200263637" value="200263637" /><span>14.</span></div><div class="rslt"><div class="rsltcont"><p class="title"><a href="/geo/query/acc.cgi?acc=GSE263637" ref="ordinalpos=14&ncbi_uid=200263637&link_uid=200263637">CTCF depletion uncouples the role of enhancer-promoter interactions and higher-order chromatin hubs in gene regulation during cellular differentiation [ChIPmentation]</a></p><div class="supp">(Submitter supplied) Enhancers and promoters interact in 3D chromatin structures to regulate gene expression. The mechanisms that drive the formation of these structures and their function during cellular differentiation are incompletely understood. Here, we study the structure-function relationship of the genome in a lymphoid-to-myeloid differentiation system at very high resolution. We demonstrate a close correlation between binding of regulatory proteins, formation of chromatin interactions, and gene expression.<a href="/geo/query/acc.cgi?acc=GSE263637"> more...</a><dl class="details lefty"><dt>Organism: </dt><dd class="lng_ln">Homo sapiens</dd></dl><dl class="details lefty"><dt>Type: </dt><dd class="lng_ln"><b>Genome binding/occupancy profiling by high throughput sequencing</b></dd></dl><dl class="details"><dt>Platforms: </dt><dd class="lng_ln"><a href="/geo/query/acc.cgi?acc=GPL21697">GPL21697</a> <a href="/geo/query/acc.cgi?acc=GPL30173">GPL30173</a> </dd><dt><a href="/gds/?term=GSE263637[ACCN] AND gsm[ETYP]">42 Samples</a></dt><dd></dd></dl><a href="/geo/download/?acc=GSE263637">Download data: BW</a></div><div class="aux"><div class="resc"><span class="src">Series</span><dl class="rprtid"><dt>Accession: </dt><dd>GSE263637</dd></dl><dl class="rprtid"><dt>ID:</dt> <dd>200263637</dd> </dl></div><p class="links nohighlight"></p></div></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><label for="UidCheckBox200262984" class="ui-helper-hidden-accessible">Select item 200262984</label><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_RVDocSum.uid" sid="15" type="checkbox" id="UidCheckBox200262984" value="200262984" /><span>15.</span></div><div class="rslt"><div class="rsltcont"><p class="title"><a href="/geo/query/acc.cgi?acc=GSE262984" ref="ordinalpos=15&ncbi_uid=200262984&link_uid=200262984">Analysis of amygdala neuron chromatin accessibility by NR2F2</a></p><div class="supp">(Submitter supplied) Neuroimmune interactions—signals transmitted between immune and brain cells—regulate many aspects of tissue physiology including responses to psychological stress, which can predispose individuals to develop neuropsychiatric diseases. Still, the interactions between hematopoietic and brain-resident cells that influence complex behaviors are poorly understood. Here, we used a combination of genomic and behavioral screens to demonstrate that astrocytes in the amygdala limit stress-induced fear behavior through EGFR.<a href="/geo/query/acc.cgi?acc=GSE262984"> more...</a><dl class="details lefty"><dt>Organism: </dt><dd class="lng_ln">Mus musculus</dd></dl><dl class="details lefty"><dt>Type: </dt><dd class="lng_ln"><b>Genome binding/occupancy profiling by high throughput sequencing</b></dd></dl><dl class="details"><dt>Platform: </dt><dd class="lng_ln"><a href="/geo/query/acc.cgi?acc=GPL21626">GPL21626</a> </dd><dt><a href="/gds/?term=GSE262984[ACCN] AND gsm[ETYP]">8 Samples</a></dt><dd></dd></dl><a href="/geo/download/?acc=GSE262984">Download data: NARROWPEAK</a></div><div class="aux"><div class="resc"><span class="src">Series</span><dl class="rprtid"><dt>Accession: </dt><dd>GSE262984</dd></dl><dl class="rprtid"><dt>ID:</dt> <dd>200262984</dd> </dl></div><p class="links nohighlight"></p></div></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><label for="UidCheckBox200239702" class="ui-helper-hidden-accessible">Select item 200239702</label><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_RVDocSum.uid" sid="16" type="checkbox" id="UidCheckBox200239702" value="200239702" /><span>16.</span></div><div class="rslt"><div class="rsltcont"><p class="title"><a href="/geo/query/acc.cgi?acc=GSE239702" ref="ordinalpos=16&ncbi_uid=200239702&link_uid=200239702">Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation</a></p><div class="supp">(Submitter supplied) Circular RNA (circRNA) is a class of noncoding RNA with regulatory potentials. It is unexplored how they may be functionally involved in the transdifferentiation of prostate and lung adenocarcinoma to neuroendocrine prostate cancer (NEPC) and small cell lung cancer (SCLC). Here we identified an exceptionally abundant circRNA circRMST predominantly expressed in NEPC and SCLC and conserved between humans and mice.<a href="/geo/query/acc.cgi?acc=GSE239702"> more...</a><dl class="details lefty"><dt>Organism: </dt><dd class="lng_ln">Homo sapiens</dd></dl><dl class="details lefty"><dt>Type: </dt><dd class="lng_ln">Expression profiling by high throughput sequencing; <b>Genome binding/occupancy profiling by high throughput sequencing</b></dd></dl><dl class="details"><dt>Platforms: </dt><dd class="lng_ln"><a href="/geo/query/acc.cgi?acc=GPL24676">GPL24676</a> <a href="/geo/query/acc.cgi?acc=GPL34284">GPL34284</a> <a href="/geo/query/acc.cgi?acc=GPL20301">GPL20301</a> </dd><dt><a href="/gds/?term=GSE239702[ACCN] AND gsm[ETYP]">27 Samples</a></dt><dd></dd></dl><a href="/geo/download/?acc=GSE239702">Download data: BW, CSV</a></div><div class="aux"><div class="resc"><span class="src">Series</span><dl class="rprtid"><dt>Accession: </dt><dd>GSE239702</dd></dl><dl class="rprtid"><dt>ID:</dt> <dd>200239702</dd> </dl></div><p class="links nohighlight"></p></div></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><label for="UidCheckBox200263243" class="ui-helper-hidden-accessible">Select item 200263243</label><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_RVDocSum.uid" sid="17" type="checkbox" id="UidCheckBox200263243" value="200263243" /><span>17.</span></div><div class="rslt"><div class="rsltcont"><p class="title"><a href="/geo/query/acc.cgi?acc=GSE263243" ref="ordinalpos=17&ncbi_uid=200263243&link_uid=200263243">Circulating, cell-free methylated DNA reveals cellular sources of allograft injury after liver transplant [Reference Celltype Chromatin]</a></p><div class="supp">(Submitter supplied) Molecular biomarkers to monitor changes after liver transplant are essential to reveal mechanisms of injury, guide clinical decision-making and improve patient outcomes. Current approaches have limited scope and are unable to differentiate between host and graft amongst the causes of graft injury. Here, we utilize circulating, cell-free methylated DNA released from dying cells to monitor cellular damages after liver transplant impacting the graft tissue as well as host organs.<a href="/geo/query/acc.cgi?acc=GSE263243"> more...</a><dl class="details lefty"><dt>Organism: </dt><dd class="lng_ln">Homo sapiens</dd></dl><dl class="details lefty"><dt>Type: </dt><dd class="lng_ln"><b>Genome binding/occupancy profiling by high throughput sequencing</b></dd></dl><dl class="details"><dt>Platform: </dt><dd class="lng_ln"><a href="/geo/query/acc.cgi?acc=GPL24676">GPL24676</a> </dd><dt><a href="/gds/?term=GSE263243[ACCN] AND gsm[ETYP]">4 Samples</a></dt><dd></dd></dl><a href="/geo/download/?acc=GSE263243">Download data: BW</a></div><div class="aux"><div class="resc"><span class="src">Series</span><dl class="rprtid"><dt>Accession: </dt><dd>GSE263243</dd></dl><dl class="rprtid"><dt>ID:</dt> <dd>200263243</dd> </dl></div><p class="links nohighlight"></p></div></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><label for="UidCheckBox200262989" class="ui-helper-hidden-accessible">Select item 200262989</label><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_RVDocSum.uid" sid="18" type="checkbox" id="UidCheckBox200262989" value="200262989" /><span>18.</span></div><div class="rslt"><div class="rsltcont"><p class="title"><a href="/geo/query/acc.cgi?acc=GSE262989" ref="ordinalpos=18&ncbi_uid=200262989&link_uid=200262989">Psychedelic control of neuroimmune interactions governing fear</a></p><div class="supp">(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.<dl class="details lefty"><dt>Organism: </dt><dd class="lng_ln">Homo sapiens; Mus musculus</dd></dl><dl class="details lefty"><dt>Type: </dt><dd class="lng_ln">Expression profiling by high throughput sequencing; <b>Genome binding/occupancy profiling by high throughput sequencing</b></dd></dl><dl class="details"><dt><a href="/gds/?term=GSE262989[ACCN] AND gpl[ETYP]">4 related Platforms</a></dt><dd></dd><dt><a href="/gds/?term=GSE262989[ACCN] AND gsm[ETYP]">108 Samples</a></dt><dd></dd></dl><a href="/geo/download/?acc=GSE262989">Download data: H5, H5AD, NARROWPEAK, TAR, TXT, XLSX</a></div><div class="aux"><div class="resc"><span class="src">Series</span><dl class="rprtid"><dt>Accession: </dt><dd>GSE262989</dd></dl><dl class="rprtid"><dt>ID:</dt> <dd>200262989</dd> </dl></div><p class="links nohighlight"></p></div></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><label for="UidCheckBox200290359" class="ui-helper-hidden-accessible">Select item 200290359</label><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_RVDocSum.uid" sid="19" type="checkbox" id="UidCheckBox200290359" value="200290359" /><span>19.</span></div><div class="rslt"><div class="rsltcont"><p class="title"><a href="/geo/query/acc.cgi?acc=GSE290359" ref="ordinalpos=19&ncbi_uid=200290359&link_uid=200290359">Differential Cellular Mechanisms Underlie Language and Executive Decline in Amyotrophic Lateral Sclerosis</a></p><div class="supp">(Submitter supplied) Half of all amyotrophic lateral sclerosis (ALS) patients demonstrate a spectrum of cognitive and behavioral changes over the course of the disease, but the mechanisms underlying this heterogeneity remain unclear. We assemble a high-resolution cellular map of prefrontal cortex regions of the ALS brain by integrating spatial and single-nucleus transcriptomic profiles of a cognitively stratified ALS patient cohort that includes non-neuropathological controls.<a href="/geo/query/acc.cgi?acc=GSE290359"> more...</a><dl class="details lefty"><dt>Organism: </dt><dd class="lng_ln">Homo sapiens</dd></dl><dl class="details lefty"><dt>Type: </dt><dd class="lng_ln">Expression profiling by high throughput sequencing; <b>Genome binding/occupancy profiling by high throughput sequencing</b></dd></dl><dl class="details"><dt>Platform: </dt><dd class="lng_ln"><a href="/geo/query/acc.cgi?acc=GPL34281">GPL34281</a> </dd><dt><a href="/gds/?term=GSE290359[ACCN] AND gsm[ETYP]">96 Samples</a></dt><dd></dd></dl><a href="/geo/download/?acc=GSE290359">Download data: CSV, H5, H5AD, TBI, TSV</a></div><div class="aux"><div class="resc"><span class="src">Series</span><dl class="rprtid"><dt>Accession: </dt><dd>GSE290359</dd></dl><dl class="rprtid"><dt>ID:</dt> <dd>200290359</dd> </dl></div><p class="links nohighlight"></p></div></div></div></div><div class="rprt"><div class="rprtnum nohighlight"><label for="UidCheckBox200284303" class="ui-helper-hidden-accessible">Select item 200284303</label><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_RVDocSum.uid" sid="20" type="checkbox" id="UidCheckBox200284303" value="200284303" /><span>20.</span></div><div class="rslt"><div class="rsltcont"><p class="title"><a href="/geo/query/acc.cgi?acc=GSE284303" ref="ordinalpos=20&ncbi_uid=200284303&link_uid=200284303">Transcription-coupled AID Deamination Damage Depends on ELOF1-associated RNA Polymerase II [ChIP-seq]</a></p><div class="supp">(Submitter supplied) In adaptive immunity, transcription-coupled damage is introduced into antibody genes by activation-induced cytidine deaminase (AID) to diversify antibody repertoire. However, the coordination between transcription and DNA damage/repair remains elusive. Here, we find that transcription elongation factor 1 (ELOF1) stabilizes paused RNA polymerase II (RNAPII) at transcription barriers, providing a platform for transcription-coupled DNA damage/repair.<a href="/geo/query/acc.cgi?acc=GSE284303"> more...</a><dl class="details lefty"><dt>Organism: </dt><dd class="lng_ln">Mus musculus</dd></dl><dl class="details lefty"><dt>Type: </dt><dd class="lng_ln"><b>Genome binding/occupancy profiling by high throughput sequencing</b>; Other</dd></dl><dl class="details"><dt>Platforms: </dt><dd class="lng_ln"><a href="/geo/query/acc.cgi?acc=GPL24247">GPL24247</a> <a href="/geo/query/acc.cgi?acc=GPL21273">GPL21273</a> </dd><dt><a href="/gds/?term=GSE284303[ACCN] AND gsm[ETYP]">68 Samples</a></dt><dd></dd></dl><a href="/geo/download/?acc=GSE284303">Download data: BW</a></div><div class="aux"><div class="resc"><span class="src">Series</span><dl class="rprtid"><dt>Accession: </dt><dd>GSE284303</dd></dl><dl class="rprtid"><dt>ID:</dt> <dd>200284303</dd> </dl></div><p class="links nohighlight"></p></div></div></div></div></div>
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<div id="taxonomy-subset-container" rel="gds"><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_MultiItemSupl.Taxport.TxView" sid="1" type="hidden" value="" /><input name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Gds_MultiItemSupl.Taxport.TxListSize" sid="1" type="hidden" value="" /><div style="display:none">db=gds|term=(genome%20binding/occupancy%20profiling%20by%20array[DataSet%20Type]%20OR%20genome%20binding/occupancy%20profiling%20by%20genome%20tiling%20array[DataSet%20Type]%20OR%20genome%20binding/occupancy%20profiling%20by%20high%20throughput%20sequencing[DataSet%20Type])%20AND%20gse[Entry%20Type]|query=481|qty=595|blobid=MCID_67c826365b08ab4a1737bcad|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?</div><dl style="display:none"><em> </em><a href="javascript:void(0)">Taxonomic Groups</a>
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<textarea name="EntrezSystem2.PEntrez.Gds.Gds_ResultsPanel.Discovery_SearchDetails.SearchDetailsTerm" sid="1" class="searchdetails_term" cols="30" rows="5" db="gds">(genome binding/occupancy profiling by array[DataSet Type] OR genome binding/occupancy profiling by genome tiling array[DataSet Type] OR genome binding/occupancy profiling by high throughput sequencing[DataSet Type]) AND gse[Entry Type]</textarea>
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<a class="seemore" href="/gds/details?querykey=481" ref="log$=details">
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See more...
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<a href="/geo/">GEO Home</a>
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|
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<a href="/geo/info/">GEO Documentation</a>
|
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<li>
|
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<a href="/geo/info/datasets.html">About GEO DataSets</a>
|
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|
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|
||
<a href="/geo/info/qqtutorial.html">Construct a Query</a>
|
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=1" href="/portal/utils/pageresolver.fcgi?recordid=67c82636feee5b00acfef511">(genome binding/occupancy profiling by array[DataSet Type] OR gen... <span class="number">(44816)</span></a>
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<div class="ralinkpop offscreen_noflow">(genome binding/occupancy profiling by array[DataSet Type] OR genome binding/occupancy profiling by genome tiling array[DataSet Type] OR genome binding/occupancy profiling by high throughput sequencing[DataSet Type]) AND gse[Entry Type]<div class="brieflinkpopdesc">Search</div></div>
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<div class="tertiary">GEO DataSets</div>
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<a class="htb" ref="log$=activity&linkpos=2" href="/portal/utils/pageresolver.fcgi?recordid=67c82635feee5b00acfeebbc">3013736 2686538 2270403 1669752 1619900 1619899 539976 99122[uid] <span class="number">(8)</span></a>
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<a class="htb ralinkpopperctrl" ref="log$=activity&linkpos=3" href="/portal/utils/pageresolver.fcgi?recordid=67c82634feee5b00acfee3e4">Mechanical strain effect on fetal lung type II epithelial cells</a>
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<div class="ralinkpop offscreen_noflow">Mechanical strain effect on fetal lung type II epithelial cells<div class="brieflinkpopdesc">Accession: GDS2225</div></div>
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<a class="htb" ref="log$=activity&linkpos=4" href="/portal/utils/pageresolver.fcgi?recordid=67c82634b70fbb196009048f">(GDS2225[ACCN]) AND GDS[filter] <span class="number">(1)</span></a>
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<a class="htb" ref="log$=activity&linkpos=5" href="/portal/utils/pageresolver.fcgi?recordid=67c826316d1ec11b6f625326">NLM Catalog Links for Books (Select 1501650) <span class="number">(1)</span></a>
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