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<h1>Board of Regents Working Group (BoR WG) members</h1>
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</div>
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</section>
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<div class="page-content">
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<div class="member-profile">
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<h2 id="hannah-carey-phd">Hannah Carey, PhD</h2>
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<p><img src="/core/assets/datasets/images/cgr/headshots/hannah-carey.jpg" alt="Hannah Carey"/></p>
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<div class="member-bio">
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||
<p>Hannah Carey is Professor Emeritus in the School of Veterinary Medicine at the University of Wisconsin-Madison. She
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received her PhD in Zoology from the University of California, Davis and completed postdoctoral training in
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gastrointestinal physiology at the University of Nevada-Reno School of Medicine and the Ohio State College of Medicine.<br/>
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Her research investigates adaptations of the gastrointestinal tract and its microbiome to extreme changes in physiology
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and nutrition in hibernating mammals, and their potential applications to biomedicine. Dr. Carey is a Past President of
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the American Physiological Society and the Federation of American Societies of Experimental Biology, and is a AAAS
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||
Fellow. She served as a rotating Program Officer in the Directorate for Biological Sciences at the National Science
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||
Foundation (NSF) from 2010-2011. </p>
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||
</div>
|
||
</div>
|
||
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||
<div class="member-profile">
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||
<h2 id="wayne-n-frankel-phd">Wayne N. Frankel, PhD</h2>
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||
<p><img src="/core/assets/datasets/images/cgr/headshots/wayne-frankel.jpg" alt="Wayne N. Frankel"/></p>
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||
<div class="member-bio">
|
||
<p>Wayne N. Frankel, Ph.D. is a Professor in the Department of Genetics & Development and in the Institute for Genomic
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||
Medicine at Columbia University (New York, NY). Frankel earned his masters and doctorate degrees from Albert Einstein
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College of Medicine (Bronx, NY), and continued his training as a postdoc at Tufts University School of Medicine
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||
(Boston, MA).</p>
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||
<p>In 1992 he joined the faculty of The Jackson Laboratory (Bar Harbor, ME) where using mouse models he pioneered various
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approaches to understand the genetic basis of epilepsy, initially pursuing gene discovery by aligning mouse seizure
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genes with human epilepsy GWAS hits and pathogenic variants detected by next-gen sequencing. </p>
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||
<p>As human epilepsy gene discovery advanced, he reversed the approach to model human variants in engineered mice, an
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||
approach he has continued since relocating to Columbia in 2015. In studying over a dozen different genetic models of
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||
DEE in collaborations with neurophysiologists and clinicians at Columbia and externally, his two broad objectives are
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||
identifying mechanisms that converge across different genetic etiologies and in advancing treatment by focusing on
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genetic therapies in otherwise intractable forms of epilepsy. </p>
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||
<p>Frankel has authored or co-authored over 140 research publications, was the founding Editor-in-Chief of PLOS Genetics
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||
and has served in various national and international scientific advisory capacities, both in the US (NIH) and
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||
international (EU). </p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="member-profile">
|
||
<h2 id="kristi-holmes-phd-chair">Kristi Holmes, PhD (Chair)</h2>
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||
<p><img src="/core/assets/datasets/images/cgr/headshots/kristi-holmes.jpg" alt="Kristi Holmes"/></p>
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||
<div class="member-bio">
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||
<p>Kristi Holmes is the Director of Galter Health Sciences Library & Learning Center and Professor of Preventive Medicine
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||
(Health & Biomedical Informatics) and Medical Education at Northwestern University. She is deeply committed to
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||
empowering data discovery and equitable access to knowledge, including the development of computational and social
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||
architectures to support these goals. Dr. Holmes directs evaluation for several large centers and institutes,
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||
training grants and other strategic initiatives, including the Northwestern University Clinical and Translational
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||
Sciences Institute (NUCATS), where she serves as an Associate Director of the institute. She is the Chief of Knowledge
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||
Management at the Northwestern University Institute for Augmented Intelligence in Medicine (I.AIM) and actively
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||
collaborates on several informatics and data science strategic initiatives, bringing experience with highly cooperative
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||
technical information projects on the local, national, and international level. Her advisory roles include service on
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||
the NLM Board of Regents, the InCommon Steering Committee, the Research Centers in Minority Institutions (RCMI)
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||
Coordinating Center External Advisory Committee, and her team is also a core development partner with CERN on the
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||
InvenioRDM project. Before joining Northwestern University, she was a bioinformaticist at Washington University in St.
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Louis. She earned a PhD in Biochemistry from Iowa State University.</p>
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||
</div>
|
||
</div>
|
||
|
||
<div class="member-profile">
|
||
<h2 id="ani-w-manichaikul-phd">Ani W. Manichaikul, PhD</h2>
|
||
<p><img src="/core/assets/datasets/images/cgr/headshots/ani-manichaikul.jpg" alt="Ani W. Manichaikul"/></p>
|
||
<div class="member-bio">
|
||
<p>Ani W. Manichaikul is a biostatistician and statistical geneticist with interests in genetic analysis of complex
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disease for both rare and common genetic variants in studies of multi-ethnic and admixed populations. Among many of
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||
my current efforts, I work actively as an analyst in MESA, performing genetic analyses of a variety of traits
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||
(including pulmonary function, emphysema, subclinical atherosclerosis, CVD events, inflammatory markers, fatty acids,
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||
lipids, nutrition) in combined samples of families and unrelated individuals. Current efforts in my group include
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||
integration of genomic and transcriptomic data with application to lung disease traits, translational studies in
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||
collaboration with investigators performing animal studies, assay of protein levels in MESA participants to follow-up
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||
of recent genetic association findings, and statistical mediation analysis of inflammatory biomarkers in the
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||
pathogenesis of disease. Beyond MESA, I collaborate actively on translational research efforts with basic scientists at
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||
the University of Virginia, with a focus on bridging candidate gene association studies in humans with mouse studies,
|
||
including gene mapping and phenotypic characterization of knockout animals. </p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="member-profile">
|
||
<h2 id="len-pennacchio-phd">Len Pennacchio, PhD</h2>
|
||
<p><img src="/core/assets/datasets/images/cgr/headshots/len-pennacchio.jpg" alt="Len Pennacchio"/></p>
|
||
<div class="member-bio">
|
||
<p>Dr. Len Pennacchio is a Senior Scientist at the Lawrence Berkeley Laboratory (LBL), Deputy Director of the DOE Joint
|
||
Genome Institute, and Adjunct Professor at the University of California Berkeley. He received his PhD in Genetics from
|
||
Stanford University in 1998 under Rick Myers and then served as a DOE Alexander Hollaender Distinguished Fellow at LBL
|
||
under Eddy Rubin. He has authored over 170 publications and received the Presidential Early Career Award for Scientists
|
||
and Engineers (PECASE) from the White House for his contributions to the Human Genome Project and understanding
|
||
mammalian gene regulation in vivo. Dr. Pennacchio has an extensive background in mammalian genetics and genomics as
|
||
well as with DNA sequencing technologies and their application to address outstanding issues in both the biomedical,
|
||
energy, and environment sectors. He serves in numerous advisory roles such as NHGRI’s National Council, NHGRI’s Genome
|
||
Sequencing Program, the Centre for Genomic Research at the University of Liverpool, as a permanent member of NIH’s GCAT
|
||
Study Section. He also is an Organizer and Co-Chair of three separate annual Advances in Genome Biology & Technology
|
||
(AGBT) meetings as well as a “Systems Biology of Gene Regulation and Genome Editing” meeting hosted by Cold Spring
|
||
Harbor Asia. Currently his research is heavily focused on understanding the spectrum of DNA mutations that contribute
|
||
to human disease through in vivo functional studies. </p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="member-profile">
|
||
<h2 id="alejandro-snchez-alvarado-phd">Alejandro Sánchez Alvarado, PhD</h2>
|
||
<p><img src="/core/assets/datasets/images/cgr/headshots/alejandro-sanchez-alvarado.jpg" alt="Alejandro Sánchez Alvarado"/></p>
|
||
<div class="member-bio">
|
||
<p>Sánchez Alvarado received a BS in molecular biology and chemistry from Vanderbilt University in Nashville, TN, and a
|
||
PhD in pharmacology and cell biophysics from the University of Cincinnati College of Medicine in Cincinnati, OH. He
|
||
performed postdoctoral and independent research at the Carnegie Institution of Washington, Department of Embryology in
|
||
Baltimore, MD. In 2002, he joined the faculty of the University of Utah School of Medicine in Salt Lake City where he
|
||
held the H.A. & Edna Benning Presidential Endowed Chair. In 2005, he was named a Howard Hughes Medical Institute
|
||
Investigator. He joined Stowers Institute for Medical Research in Kansas City in 2011 and became Scientific Director of
|
||
the Stowers Institute in 2019 and is now serving as the Institute’s Executive Director & Chief Scientific Officer. </p>
|
||
<p>Sánchez Alvarado is a member of the National Academy of Science, the American Academy of Arts and Sciences, and the
|
||
Latin American Academy of Sciences, a Kavli Fellow of the National Academy of Sciences USA, a Fellow of the Marine
|
||
Biological Laboratory in Woods Hole, MA, a recipient of a National Institutes of Health MERIT award, Priscilla Wood
|
||
Neaves Chair in the Biomedical Sciences, and the EE Just Medal for Scientific Achievement. He has served on numerous
|
||
scientific advisory committees and boards including the National Advisory Council of the National Institute of General
|
||
Medical Sciences, National Institutes of Health, and presently serves on the Board of Directors of American Century
|
||
Investments. </p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="member-profile">
|
||
<h2 id="kenneth-stuart-phd">Kenneth Stuart, PhD</h2>
|
||
<p><img src="/core/assets/datasets/images/cgr/headshots/kenneth-stuart.jpg" alt="Kenneth Stuart"/></p>
|
||
<div class="member-bio">
|
||
<p>Kenneth D. Stuart, Ph.D. is a Principal Investigator at the Seattle Children's Research Institute (SCRI) and a
|
||
Professor in the Division of Infectious Diseases in the School of Medicine at the University of Washington where he
|
||
was previously chair of the Department of Pathobiology. He is also an Affiliate Investigator in the Vaccine and
|
||
Infectious Disease Division at the Fred Hutchinson Cancer Research Center. He founded The Seattle Biomedical Research
|
||
Institute (SBRI) that focused on global infectious diseases including malaria, HIV/AIDS and tuberculosis, and neglected
|
||
parasitic diseases which merged with the Center from Global Infectious Disease Research at SCRI. </p>
|
||
<p>He received a BA in Biology from Northeastern University, Boston, MA; a MA in Biology from Wesleyan University,
|
||
Middletown, CT; and a Ph.D. in Zoology from the University of Iowa, Iowa City, IA. He received postdoctoral training in
|
||
biochemistry at the National Institute for Medical Research, London and SUNY Stony Brook before becoming an Assistant
|
||
Professor of Biology at the University of South Florida (1972-76). He relocated to Seattle in 1976 and created SBRI. </p>
|
||
<p>Dr. Stuart is an expert in molecular and cell biology and performs research on complex pathogens and the diseases that
|
||
they cause including African sleeping sickness, Chagas disease, leishmaniasis, and malaria. He led the formation of the
|
||
international consortium that sequenced the genomes of the parasites which laid the foundation for many scientific
|
||
advances by numerous researchers. He is particularly recognized for his groundbreaking studies of RNA editing and is
|
||
also known for his numerous contributions to the understanding of protozoan pathogens that cause extensive human
|
||
disease, primarily in less developed countries. These include immune evasion processes, viral contribution to
|
||
pathogenesis, pathogen regulatory processes and human immune responses to malaria infection and vaccination. </p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="member-profile">
|
||
<h2 id="tandy-warnow-phd">Tandy Warnow, PhD</h2>
|
||
<p><img src="/core/assets/datasets/images/cgr/headshots/tandy-warnow.jpg" alt="Tandy Warnow"/></p>
|
||
<div class="member-bio">
|
||
<p>Tandy Warnow is the Grainger Distinguished Chair in Engineering, and Professor and Associate Head of Computer Science
|
||
at the University of Illinois at Urbana-Champaign. Tandy received her PhD in Mathematics at UC Berkeley under the
|
||
direction of Gene Lawler and did postdoctoral training with Simon Tavaré and Michael Waterman at USC. Her research
|
||
combines computer science, statistics, and discrete mathematics, focusing on developing improved models and algorithms
|
||
for reconstructing complex and large-scale evolutionary histories in biology and historical linguistics. Her main
|
||
research is focused on algorithmic problems in computational biology with the aim of developing methods that biologists
|
||
will use and that will have transformative accuracy and scalability. Her current work is on large-scale and complex
|
||
estimation problems in phylogenomics (i.e., genome-scale phylogeny estimation), multiple sequence alignment, and
|
||
metagenomics. Her awards include the NSF Young Investigator Award (1994), the David and Lucile Packard Foundation Award
|
||
(1996), a Radcliffe Institute Fellowship (2003), and the John Simon Guggenheim Foundation Fellowship (2011). She was
|
||
elected a Fellow of the Association for Computing Machinery (ACM) in 2015, of the International Society for
|
||
Computational Biology (ISCB) in 2017, and of the American Association for the Advancement of Science (AAAS) in 2021. </p>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="member-profile">
|
||
<h2 id="cathy-wu-phd">Cathy Wu, PhD</h2>
|
||
<p><img src="/core/assets/datasets/images/cgr/headshots/cathy-wu.jpg" alt="Cathy Wu"/></p>
|
||
<div class="member-bio">
|
||
<p>Dr. Wu is the Unidel Edward G. Jefferson Chair Professor in Engineering and Computer Science at the University of
|
||
Delaware and has served as the Founding Director of the Center for Bioinformatics and Computational Biology since 2010
|
||
and the Data Science Institute since 2018. She received her PhD from Purdue University and has conducted bioinformatics
|
||
research for 30 years in areas encompassing genomic and protein sequence and functional annotation, biological text
|
||
mining and natural language processing, biological ontology, semantic data integration, knowledge network analysis, and
|
||
bioinformatics cyberinfrastructure. She has published 300 peer-reviewed publications with an h-index of 72 and been
|
||
recognized as a Highly Cited Researcher. </p>
|
||
<p>As the Director of the Protein Information Resource (PIR), she has co-led the international UniProt Consortium since
|
||
2002, which now serves as a hub of protein knowledge with over 8 million pageviews monthly from >900,000 unique sites
|
||
worldwide. She is an IEEE Fellow, ACM Fellow, and AAIA Fellow, and received the Purdue Distinguished Agriculture Alumni
|
||
Award. She has served on the National Institute of General Medical Sciences Advisory Council (2017-2021), the ACM SIGBio
|
||
Board of Directors (since 2010), and the Editorial Board of the IEEE/ACM Transactions on Computational Biology and
|
||
Bioinformatics (TCBB) (since 2014). She has launched several degree programs since 2010, including the MS, PSM, PhD,
|
||
and graduate certificate programs in Bioinformatics Data Science, as well as a new NIH T32 Graduate Training Program in
|
||
Computational Biology, Bioinformatics and Biomedical Data Science. </p>
|
||
</div>
|
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</div>
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<a href="https://www.nih.gov/institutes-nih/nih-office-director/office-communications-public-liaison/freedom-information-act-office"
|
||
class="text-white">FOIA</a><br>
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<a href="https://www.hhs.gov/vulnerability-disclosure-policy/index.html" class="text-white" id="vdp">HHS Vulnerability Disclosure</a></p>
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<p><a class="supportLink text-white" href="https://support.nlm.nih.gov/">Help</a><br>
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<li>
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<a class="text-white" href="//www.nlm.nih.gov/">NLM</a>
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</li>
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<li>
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||
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href="https://www.nih.gov/">NIH</a>
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