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<HTML><HEAD><TITLE>Analogous Enzymes 2010 update</TITLE>
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<meta http-equiv="Content-Type" content="text/html; charset=windows-1252">
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<BODY vLink=#800080 link=#0000ff><B><FONT size=+1>Table S2. An updated list of analogous enzymes</B></FONT>.
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<P>This listing was originally prepared as a web supplement to the article by M.Y. Galperin, D.R. Walker and E.V. Koonin<BR>
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<B><A href="https://www.ncbi.nlm.nih.gov/pubmed/9724324">Analogous
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enzymes: Independent inventions in enzyme evolution</B></A>, published in 1998 in <I>Genome
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Research</I> <B>8:</B> 779-790.
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<BR><A href="https://www.ncbi.nlm.nih.gov/pubmed/9724324">Abstract</A>. <A href="http://www.genome.org/cgi/content/full/8/8/779">Full text (HTML)</A>.
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An updated list of the 105 EC nodes described in that paper is available <A href="https://www.ncbi.nlm.nih.gov/Complete_Genomes/AnalEnzymes_S1.html"><B>here</B></A>.
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<P>This version is a supplementary table to the paper by M.V. Omelchenko, M.Y. Galperin, Y.I. Wolf and E.V. Koonin<BR>
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<B><A href="https://www.ncbi.nlm.nih.gov/pubmed/20433725">Non-homologous isofunctional enzymes: A systematic analysis of alternative solutions in enzyme evolution</B></A>,
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<BR>published in <I>Biology Direct</I> 2010, <B>5</B>:31.
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<A href="https://www.ncbi.nlm.nih.gov/pubmed/20433725">Abstract</A>.
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<A href="http://www.biology-direct.com/content/5/1/31/">Full text (HTML)</A>.
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<P>Submission of additional examples of analogous (non-homologous isofunctional) enzymes is most welcome.
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<BR>Please send the respective PubMed IDs to <A href="mailto:galperin@ncbi.nlm.nih.gov?subject=Analogous enzymes list">Michael Galperin</A>
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<P>
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<TABLE borderColor=808080 height="100%" width="100%" cellSpacing=2 cellPadding=2 border=1>
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<TBODY>
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<TR bgColor=#99cc66>
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<TD vAlign=top width="5%"><FONT size=+1><B>No.</B></FONT></TD>
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<TD vAlign=top width="5%"><FONT size=+1><B>EC no.</B></CENTER></FONT></TD>
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<TD vAlign=top width="15%"><FONT size=+1><B>Enzyme name</B></FONT></TD>
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<TD vAlign=top width="5%"><FONT size=+1><B>NCBI</B></FONT></TD>
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<TD vAlign=top width="5%"><FONT size=+1><B>UniProt</B></FONT></FONT></TD>
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<TD vAlign=top width="5%"><FONT size=+1><B>PDB</B></FONT></TD>
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<TD vAlign=top width="15%"><FONT size=+1><B>SCOP fold</B></FONT></TD>
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<TD vAlign=top width="5%"><FONT size=+1><B>Super-family</B></FONT></TD>
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<TD vAlign=top width="15%"><FONT size=+1><B>Family (Pfam)</B></FONT></TD>
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<TD vAlign=top width="10%"><FONT size=+1><B>Ref.</B></FONT></TD>
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<TD vAlign=top width="15%"><FONT size=+1><B>Comments</B></FONT></TD>
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</TR>
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<TR>
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<td center rowspan=2>1</td>
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<td><A href="http://enzyme.expasy.org/EC/1.1.1.1"><B>1.1.1.1</B></A></td>
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<td>Alcohol dehydrogenase</td>
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<td><A href="https://www.ncbi.nlm.nih.gov/protein/P10127">P10127</A></td>
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<td><A href="http://www.uniprot.org/uniprot/P10127">ADH4_YEAST</A></td>
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<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2BI4">2BI4</A></td>
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<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2BI4">Dehydroquinate synthase-like</A></td>
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<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P10127">SupFam</A></td>
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<td><A href="http://pfam.xfam.org/protein/P10127">Iron-contaning alcohol dehydrogenase</A></td>
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<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3282541,2823079">3282541, 2823079</A></td>
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<td rowspan=2>Two distinct structural folds</td>
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</TR>
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<TR>
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<td><A href="http://enzyme.expasy.org/EC/1.1.1.1"><B>1.1.1.1</B></A></td>
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<td>Alcohol dehydrogenase</td>
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<td><A href="https://www.ncbi.nlm.nih.gov/protein/P00334">P00334</A></td>
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<td><A href="http://www.uniprot.org/uniprot/P00334">ADH_DROME</A></td>
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<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1MG5">1MG5</A></td>
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<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1MG5">Rossmann-fold</A></td>
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<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P00334">SupFam</A></td>
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<td><A href="http://pfam.xfam.org/protein/P00334">Short chain dehydrogenase</A></td>
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<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15016358,11669613">15016358, 11669613</A></td>
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</TR>
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<TR>
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<td center rowspan=3>2</td>
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<td><A href="http://enzyme.expasy.org/EC/1.1.1.2"><B>1.1.1.2</B></A></td>
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<td>Alcohol dehydrogenase (NADP<sup>+</sup>)</td>
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<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A4X1">P0A4X1</A></td>
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<td><A href="http://www.uniprot.org/uniprot/P0A4X1">ADHC_MYCBO</A></td>
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<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1YQD">1YQD</A></td>
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<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1UUF">GroES-like and Rossmann-fold</A></td>
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<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A4X1">SupFam</A></td>
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<td><A href="http://pfam.xfam.org/protein/P0A4X1">Zinc-contaning alcohol dehydrogenase</A></td>
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<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1427101,15829607">1427101, 15829607</A></td>
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<td rowspan=3>Three distinct structural folds</td>
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</TR>
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<TR>
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<td><A href="http://enzyme.expasy.org/EC/1.1.1.2"><B>1.1.1.2</B></A></td>
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<td>Alcohol dehydrogenase (NADP<sup>+</sup>)</td>
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<td><A href="https://www.ncbi.nlm.nih.gov/protein/P14550">P14550</A></td>
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<td><A href="http://www.uniprot.org/uniprot/P14550">AK1A1_HUMAN</A></td>
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<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2ALR">2ALR</A></td>
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<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2ALR">TIM beta/alpha-barrel</A></td>
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<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P14550">SupFam</A></td>
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<td><A href="http://pfam.xfam.org/protein/P14550">Aldo/keto reductase</A></td>
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<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15299353,10486210">15299353, 10486210</A></td>
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</TR>
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<TR>
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<td><A href="http://enzyme.expasy.org/EC/1.1.1.2"><B>1.1.1.2</B></A></td>
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<td>Alcohol dehydrogenase (NADP<sup>+</sup>)</td>
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<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q09669">Q09669</A></td>
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<td><A href="http://www.uniprot.org/uniprot/Q09669">ADH4_SCHPO</A></td>
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<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1O2D">1O2D</A></td>
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<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1OJ7">Dehydroquinate synthase-like</A></td>
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<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q09669">SupFam</A></td>
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<td><A href="http://pfam.xfam.org/protein/Q09669">Iron-contaning alcohol dehydrogenase</A></td>
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<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15327949,14705036">15327949, 14705036</A></td>
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</TR>
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<TR>
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<td center rowspan=2>3</td>
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<td><A href="http://enzyme.expasy.org/EC/1.1.1.27"><B>1.1.1.27</B></A></td>
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<td>L-lactate dehydrogenase</td>
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<td><A href="https://www.ncbi.nlm.nih.gov/protein/P00338">P00338</A></td>
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<td><A href="http://www.uniprot.org/uniprot/P00338">LDHA_HUMAN</A></td>
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<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1EZ4">1EZ4</A></td>
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<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1EZ4">Rossmann-fold and LDH C-terminal domain-like</A></td>
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<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P00338">SupFam</A></td>
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<td><A href="http://pfam.xfam.org/protein/P00338">Lactate AND malate dehydrogenases</A></td>
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<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11807949">11807949</A></td>
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<td rowspan=2>Two distinct structural folds</td>
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</TR>
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<TR>
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<td><A href="http://enzyme.expasy.org/EC/1.1.1.27"><B>1.1.1.27</B></A></td>
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<td>L-lactate dehydrogenase</td>
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<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q07251">Q07251</A></td>
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<td><A href="http://www.uniprot.org/uniprot/Q07251">LDH_RALEH</A></td>
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<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1VBI">1VBI</A></td>
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<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1rfm">L-sulfolactate dehydrogenase-like</A></td>
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<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q07251">SupFam</A></td>
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<td><A href="http://pfam.xfam.org/protein/Q07251">Malate/L-Lactate dehydrogenases</A></td>
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<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8405966">8405966</A></td>
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</TR>
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<TR>
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<td center rowspan=2>4</td>
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<td><A href="http://enzyme.expasy.org/EC/1.1.1.28"><B>1.1.1.28</B></A></td>
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<td>D-lactate dehydrogenase</td>
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<td><A href="https://www.ncbi.nlm.nih.gov/protein/P52643">P52643</A></td>
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<td><A href="http://www.uniprot.org/uniprot/P52643">LDHD_ECOLI</A></td>
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<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2DLD">2DLD</A></td>
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<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2DLD">Rossmann-fold and Flavodoxin-like</A></td>
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<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P52643">SupFam</A></td>
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<td><A href="http://pfam.xfam.org/protein/P52643">Formate/glycerate dehydrogenases</A></td>
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<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9025293">9025293</A></td>
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<td rowspan=2>Two distinct structural folds</td>
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</TR>
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<TR>
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<td><A href="http://enzyme.expasy.org/EC/1.1.1.28"><B>1.1.1.28</B></A></td>
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<td>D-lactate dehydrogenase</td>
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<td><A href="https://www.ncbi.nlm.nih.gov/protein/P06149">P06149</A></td>
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<td><A href="http://www.uniprot.org/uniprot/P06149">DLD_ECOLI</A></td>
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<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1F0X">1F0X</A></td>
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<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1F0X">FAD-binding and Ferredoxin-like</A></td>
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<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P06149">SupFam</A></td>
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<td><A href="http://pfam.xfam.org/protein/P06149">D-lactate dehydrogenase</A></td>
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<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10944213">10944213</A></td>
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</TR>
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<TR>
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<td center rowspan=2>5</td>
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<td><A href="http://enzyme.expasy.org/EC/1.1.1.37"><B>1.1.1.37</B></A></td>
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<td>Malate dehydrogenase</td>
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<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q07841">Q07841</A></td>
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<td><A href="http://www.uniprot.org/uniprot/Q07841">MDH_HALMA</A></td>
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<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2J5K">2J5K</A></td>
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<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2J5K">Rossmann-fold and LDH C-terminal domain-like</A></td>
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<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q07841">SupFam</A></td>
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<td><A href="http://pfam.xfam.org/protein/Q07841">L-lactate/malate dehydrogenases</A></td>
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<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8476859,10653643">8476859, 10653643</A></td>
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<td rowspan=2>Two distinct structural folds</td>
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</TR>
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<TR>
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<td><A href="http://enzyme.expasy.org/EC/1.1.1.37"><B>1.1.1.37</B></A></td>
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<td>Malate dehydrogenase</td>
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<td><A href="https://www.ncbi.nlm.nih.gov/protein/P16142">P16142</A></td>
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<td><A href="http://www.uniprot.org/uniprot/P16142">MDH_METFE</A></td>
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<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2G8Y">2G8Y</A></td>
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<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1rfm">L-sulfolactate dehydrogenase-like</A></td>
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<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P16142">SupFam</A></td>
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<td><A href="http://pfam.xfam.org/protein/P16142">Malate/L-Lactate dehydrogenases</A></td>
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<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2110059,10850983">2110059, 10850983</A></td>
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</TR>
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<TR>
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<td center rowspan=2>6</td>
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<td><A href="http://enzyme.expasy.org/EC/1.1.1.50"><B>1.1.1.50</B></A></td>
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<td>3-alpha-hydroxysteroid dehydrogenase (B-specific)</td>
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<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9ZFY9">Q9ZFY9</A></td>
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<td><A href="http://www.uniprot.org/uniprot/Q9ZFY9">Q9ZFY9_COMTE</A><BR>(<A href="http://www.uniprot.org/uniprot/P80702">DIDH_COMTE</A>)</td>
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<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1FJH">1FJH</A></td>
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<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1FJH">Rossmann-fold</A></td>
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<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9ZFY9">SupFam</A></td>
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<td><A href="http://pfam.xfam.org/protein/Q9ZFY9">Short chain dehydrogenase</A></td>
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<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8944761,10833462,11007791">8944761, 10833462, 11007791</A></td>
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<td rowspan=2>Two distinct structural folds</td>
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</TR>
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<TR>
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<td><A href="http://enzyme.expasy.org/EC/1.1.1.50"><B>1.1.1.50</B></A></td>
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<td>3-alpha-hydroxysteroid dehydrogenase (B-specific)</td>
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||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P17516">P17516</A></td>
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<td><A href="http://www.uniprot.org/uniprot/P17516">AK1C4_HUMAN</A></td>
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<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2FVL">2FVL</A></td>
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<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1S1P">TIM beta/alpha-barrel</A></td>
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||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P17516">SupFam</A></td>
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<td><A href="http://pfam.xfam.org/protein/P17516">Aldo/keto reductase</A></td>
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||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1530633,11158055">1530633, 11158055</A></td>
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||
</TR>
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||
|
||
<TR>
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||
<td center rowspan=2>7</td>
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<td><A href="http://enzyme.expasy.org/EC/1.1.1.62"><B>1.1.1.62</B></A></td>
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<td>Estradiol 17-<2D>-dehydrogenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P14061">P14061</A></td>
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||
<td><A href="http://www.uniprot.org/uniprot/P14061">DHB1_HUMAN</A></td>
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||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1FDS">1FDS</A></td>
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||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1FDS">Rossmann-fold</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P14061">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P14061">Short chain dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2846351,7663947">2846351, 7663947</A></td>
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||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
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||
<td><A href="http://enzyme.expasy.org/EC/1.1.1.62"><B>1.1.1.62</B></A></td>
|
||
<td>Estradiol 17-<2D>-dehydrogenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P70694">P70694</A></td>
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||
<td><A href="http://www.uniprot.org/uniprot/P70694">DHB5_MOUSE</A></td>
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||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1Q5M">1Q5M</A></td>
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||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1Q5M">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P70694">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P70694">Aldo/keto reductase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7737980">7737980</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>8</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.1.1.63"><B>1.1.1.63</B></A></td>
|
||
<td>Testosterone 17-<2D>-dehydrogenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O14756">O14756</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O14756">H17B6_HUMAN</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1I01">1I01</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1I01">Rossmann-fold</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O14756">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O14756">Short-chain dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11513953,11360992">11513953, 11360992</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.1.1.63"><B>1.1.1.63</B></A></td>
|
||
<td>Testosterone 17-<2D>-dehydrogenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P42330">P42330</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P42330">AK1C3_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1S1P">1S1P</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1S1P">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P42330">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P42330">Aldo/keto reductase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/14996743,9927279,15087468">14996743, 9927279, 15087468</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>9</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.1.1.64"><B>1.1.1.64</B></A></td>
|
||
<td>Testosterone 17-<2D>-dehydrogenase (NADP<sup>+</sup>)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P37058">P37058</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P37058">DHB3_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2C07">2C07</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2C07">Rossmann-fold</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P37058">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P37058">Short-chain dehydrogenases</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2558148">2558148</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.1.1.64"><B>1.1.1.64</B></A></td>
|
||
<td>Testosterone 17-<2D>-dehydrogenase (NADP<sup>+</sup>)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P42330">P42330</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P42330">AK1C3_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1S1P">1S1P</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1S1P">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P42330">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P42330">Aldo/keto reductase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/14996743,9927279">14996743, 9927279</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>10</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.1.1.82"><B>1.1.1.82</B></A></td>
|
||
<td>Malate dehydrogenase (NADP<sup>+</sup>)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q60176">Q60176</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q60176">MDH_METJA</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1HYG">1HYG</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1HYG">Rossmann-fold and LDH C-terminal domain-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q60176">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q60176">Lactate/malate dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10850983,11292347">10850983, 11292347</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.1.1.82"><B>1.1.1.82</B></A></td>
|
||
<td>Malate dehydrogenase (NADP<sup>+</sup>)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P16142">P16142</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P16142">MDH_METFE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1RFM">1RFM</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1RFM">L-sulfolactate dehydrogenase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P16142">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P16142">Malate/L-lactate dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2110059">2110059</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>11</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.1.1.189"><B>1.1.1.189</B></A></td>
|
||
<td>Prostaglandin-E2 9-reductase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P16152">P16152</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P16152">CBR1_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1WMA">1WMA</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1WMA">Rossmann-fold</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P16152">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P16152">Short-chain dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8421682">8421682</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.1.1.189"><B>1.1.1.189</B></A></td>
|
||
<td>Prostaglandin-E2 9-reductase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P80508">P80508</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P80508">PE2R_RABIT</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1Q13">1Q13</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1Q13">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P80508">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P80508">Aldo/keto reductase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8529651">8529651</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>12</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.1.1.283"><B>1.1.1.283</B></A></td>
|
||
<td>Methylglyoxal reductase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O32210">O32210</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O32210">GR_BACSU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1MZR">1MZR</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1MZR">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O32210">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O32210">Aldo/keto reductase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16232966">16232966</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.1.1.283"><B>1.1.1.283</B></A></td>
|
||
<td>Methylglyoxal reductase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q12068">Q12068</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q12068">GRE2_YEAST</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1Y1P">1Y1P</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1Y1P">Rossmann-fold</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q12068">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q12068">NAD dependent epimerase/dehydratase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3896793,12722185">3896793, 12722185</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>13</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.2.1.2"><B>1.2.1.2</B></A></td>
|
||
<td>Formate dehydrogenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P07658">P07658</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P07658">FDHF_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1FDI">1FDI</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1FDI">Formate dehydrogenase/DMSO reductase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P07658">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P07658">Molybdopterin-containing oxidoreductases</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9036855">9036855</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.2.1.2"><B>1.2.1.2</B></A></td>
|
||
<td>Formate dehydrogenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P33160">P33160</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P33160">FDH_PSESR</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2NAC">2NAC</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2NAC">Rossmann-fold and Flavodoxin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P33160">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P33160">2-hydroxyacid dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1597184,8484798">1597184, 8484798</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>14</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.2.1.10"><B>1.2.1.10</B></A></td>
|
||
<td>Acetaldehyde dehydrogenase (acetylating)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P77580">P77580</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P77580">MHPF_ECOLI</A>, <A href="http://www.uniprot.org/uniprot/Q49KG0">MHPF_PSEPU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1NVM">1NVM</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1NVM">Rossmann-fold and FwdE/ GAPDH domain-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P77580">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P77580">Prokaryotic acetaldehyde dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16782065,11264589,12764229">16782065, 11264589, 12764229</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.2.1.10"><B>1.2.1.10</B></A></td>
|
||
<td>Acetaldehyde dehydrogenase (acetylating)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q24803">Q24803</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q24803">ADH2_ENTHI</A></td>
|
||
<td>N-term is similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1AD3">1AD3</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1AD3">ALDH-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q24803">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q24803">Aldehyde dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7980441">7980441</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>15</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.2.99.2"><B>1.2.99.2</B></A></td>
|
||
<td>Carbon-monoxide dehydrogenase (acceptor)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P19919">P19919</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P19919">DCML_OLICO</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1N60">1N60</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1N60">CO dehydrogenase ISP C-domain like and others</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P19919">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P19919">Aldehyde oxidase and xanthine dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10482497,12475995">10482497, 12475995</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.2.99.2"><B>1.2.99.2</B></A></td>
|
||
<td>Carbon-monoxide dehydrogenase (acceptor)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P31896">P31896</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P31896">COOS_RHORU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1JQK">1JQK</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1SU6">Prismane protein-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P31896">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P31896">Prismane/CO dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8561463,11593006">8561463, 11593006</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>16</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.3.1.34"><B>1.3.1.34</B></A></td>
|
||
<td>2,4-dienoyl-CoA reductase (NADPH)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P42593">P42593</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P42593">FADH_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1PS9">1PS9</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1PS9">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P42593">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P42593">Oxidoreductase / NADH oxidase family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12840019">12840019</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.3.1.34"><B>1.3.1.34</B></A></td>
|
||
<td>2,4-dienoyl-CoA reductase (NADPH)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9NUI1">Q9NUI1</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9NUI1">DECR2_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1W6U">1W6U</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1W6U">Rossmann-fold</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9NUI1">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9NUI1">Short-chain dehydrogenases</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15531764">15531764</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>17</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.5.1.29"><B>1.5.1.29</B></A></td>
|
||
<td>FMN reductase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0AEN1">P0AEN1</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0AEN1">FRE_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1QFJ">1QFJ</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QFJ">Reductase/isomerase/elongation factor common domain and Ferredoxin reductase-like C-terminal NADP-linked domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0AEN1">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0AEN1">NAD(P)H-flavin reductase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2050627,10353815">2050627, 10353815</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.5.1.29"><B>1.5.1.29</B></A></td>
|
||
<td>FMN reductase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q07923">Q07923</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q07923">LOT6_YEAST</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1T0I">1T0I</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1T0I">Flavodoxin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q07923">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q07923">FMN reductase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15184374">15184374</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>18</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.5.1.34"><B>1.5.1.34</B></A></td>
|
||
<td>6,7-dihydropteridine reductase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P09417">P09417</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P09417">DHPR_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1HDR">1HDR</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1HDR">Rossmann-fold</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P09417">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P09417">Short-chain dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3033643">3033643</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.5.1.34"><B>1.5.1.34</B></A></td>
|
||
<td>6,7-dihydropteridine reductase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P38489">P38489</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P38489">NFNB_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ICR">1ICR</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1ICR">FMN-dependent nitroreductase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P38489">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P38489">Nitroreductase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3060113,11491290,15684426">3060113, 11491290, 15684426</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>19</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.6.99.3"><B>1.6.99.3</B></A></td>
|
||
<td>NADH dehydrogenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P00393">P00393</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P00393">DHNA_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1XHC">1XHC</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1XHC">FAD/NAD(P)-binding domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P00393">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P00393">NADH dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1917890">1917890</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.6.99.3"><B>1.6.99.3</B></A></td>
|
||
<td>NADH dehydrogenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P28331">P28331</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P28331">NDUS1_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2FUG">2FUG</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2FUG">Formate dehydrogenase/DMSO reductase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P28331">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P28331">Complex I 75 kDa subunit family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1935949">1935949</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>20</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.7.2.1"><B>1.7.2.1</B></A></td>
|
||
<td>Nitrite reductase (NO-forming)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P38501">P38501</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P38501">NIR_ALCFA</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2AFN">2AFN</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2AFN">Cupredoxin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P38501">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P38501">Multicopper oxidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8515232">8515232</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.7.2.1"><B>1.7.2.1</B></A></td>
|
||
<td>Nitrite reductase (NO-forming)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P24474">P24474</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P24474">NIRS_PSEAE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1NIR">1NIR</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1NIR">Cytochrome c and 8-bladed beta-propeller</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P24474">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P24474">Cytochrome D1 heme domain (Complex I 75 kDa subunit family)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2506077,11226222">2506077, 11226222</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>21</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.11.1.5"><B>1.11.1.5</B></A></td>
|
||
<td>Cytochrome-c peroxidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P14532">P14532</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P14532">CCPR_PSEAE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1EB7">1EB7</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1IQC">Cytochrome c</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P14532">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P14532">Di-heme cytochrome c peroxidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7781769,1657179,8591033">7781769, 1657179, 8591033</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.11.1.5"><B>1.11.1.5</B></A></td>
|
||
<td>Cytochrome-c peroxidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P00431">P00431</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P00431">CCPR_YEAST</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1EBE">1EBE</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1EBE">Heme-dependent peroxidases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P00431">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P00431">Peroxidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2169873,6092361">2169873, 6092361</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>22</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.11.1.6"><B>1.11.1.6</B></A></td>
|
||
<td>Catalase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P04040">P04040</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P04040">CATA_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1QQW">1QQW</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QQW">Heme-dependent catalase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P04040">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P04040">Heme-dependent catalase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10666617,3755525">10666617, 3755525</A></td>
|
||
<td rowspan=3>Three distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.11.1.6"><B>1.11.1.6</B></A></td>
|
||
<td>Catalase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P13029">P13029</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P13029">CATA_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2FXG">2FXG</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2FXG">Heme-dependent peroxidases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P13029">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P13029">Peroxidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/374409,2670897,8508796">374409, 2670897, 8508796</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.11.1.6"><B>1.11.1.6</B></A></td>
|
||
<td>Catalase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P60355">P60355</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P60355">MCAT_LACPL</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1JKU">1JKU</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1JKU">Ferritin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P60355">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P60355">Manganese catalase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8939876">8939876</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>23</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.11.1.7"><B>1.11.1.7</B></A></td>
|
||
<td>Peroxidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O08709">O08709</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O08709">PRDX6_MOUSE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1PRX">1PRX</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1PRX">Thioredoxin fold</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O08709">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O08709">Thioredoxin</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9291135,10395907,9587003">9291135, 10395907, 9587003</A></td>
|
||
<td rowspan=3>At least two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.11.1.7"><B>1.11.1.7</B></A></td>
|
||
<td>Peroxidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P05164">P05164</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P05164">PERM_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1MYP">1MYP</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1CXP">Heme-dependent peroxidases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P05164">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P05164">Animal heme peroxidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2154223">2154223</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.11.1.7"><B>1.11.1.7</B></A></td>
|
||
<td>Peroxidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P31545">P31545</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P31545">YCDB_ECOLI</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2d3q">2d3q</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2D3Q">Ferredoxin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P31545">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P31545">Dyp-type peroxidase-like</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16551627,14684913">16551627, 14684913</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>24</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.11.1.10"><B>1.11.1.10</B></A></td>
|
||
<td>Chloride peroxidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P25026">P25026</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P25026">PRXC_PSEPY</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1A88">1A88</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1A88">Alpha/beta hydrolase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P25026">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P25026">Haloperoxidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8344520">8344520</A></td>
|
||
<td rowspan=3>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.11.1.10"><B>1.11.1.10</B></A></td>
|
||
<td>Chloride peroxidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P49053">P49053</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P49053">PRXC_CURIN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1VNC">1VNC</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1VNC">Acid phosphatase/Vanadium-dependent haloperoxidase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P49053">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P49053">Type 2 phosphatidic acid phosphatase (PAP2)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9165086">9165086</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.11.1.10"><B>1.11.1.10</B></A></td>
|
||
<td>Chloride peroxidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P04963">P04963</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P04963">PRXC_CALFU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2CPO">2CPO</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2CPO">EF Hand-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P04963">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P04963">Cloroperoxidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8747463,11278701">8747463, 11278701</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>25</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.11.1.15"><B>1.11.1.15</B></A></td>
|
||
<td>Peroxiredoxin</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9Y9L0">Q9Y9L0</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9Y9L0">TDXH_AERPE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2E2G">2E2G</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2E2G">Thioredoxin fold</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9Y9L0">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9Y9L0">AhpC/TSA family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/18436649">18436649</A></td>
|
||
<td rowspan=3>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.11.1.15"><B>1.11.1.15</B></A></td>
|
||
<td>Peroxiredoxin</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A5N4">P0A5N4</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A5N4">AHPD_MYCTU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1KNC">1KNC</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1KNC">AhpD-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A5N4">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A5N4">Carboxymuconolactone decarboxylase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11914371,10766746,11799204,12761216">11914371, 10766746, 11799204, 12761216</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.11.1.15"><B>1.11.1.15</B></A></td>
|
||
<td>Peroxiredoxin</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0C0L2">P0C0L2</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0C0L2">OSMC_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1NYE">1NYE</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1NYE">OsmC-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0C0L2">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0C0L2">OsmC-like</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/14627744,15103136">14627744, 15103136</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>26</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.12.2.1"><B>1.12.2.1</B></A></td>
|
||
<td>Cytochrome-c3 hydrogenase (was 1.18.99.1)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P12944">P12944</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P12944">PHNL_DESGI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1FRV">1FRV</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1FRV">HydA/Nqo6-like and HydB/Nqo4-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P12944">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P12944">Ni-Fe hydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2651421,7854413">2651421, 7854413</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.12.2.1"><B>1.12.2.1</B></A></td>
|
||
<td>Cytochrome-c3 hydrogenase (was 1.18.99.1)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P29166">P29166</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P29166">PHF1_CLOPA</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1FEH">1FEH</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1FEH">Fe-only hydrogenase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P29166">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P29166">Iron-only hydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1911757,9836629">1911757, 9836629</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>27</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.14.99.3"><B>1.14.99.3</B></A></td>
|
||
<td>Heme oxygenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P09601">P09601</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P09601">HMOX1_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1N3U">1N3U</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1N3U">Heme oxygenase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P09601">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P09601">Heme oxygenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12500973,15285018,15049686,15522396">12500973, 15285018, 15049686, 15522396</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.14.99.3"><B>1.14.99.3</B></A></td>
|
||
<td>Heme oxygenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q6GKE0">Q6GKE0</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q6GKE0">ISDI_STAAR</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1XBW">1XBW</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1XBW">Ferredoxin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q6GKE0">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q6GKE0">Antibiotic biosynthesis monooxygenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/14570922,15774886">14570922, 15774886</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>28</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.15.1.1"><B>1.15.1.1</B></A></td>
|
||
<td>Superoxide dismutase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P09157">P09157</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P09157">SODF_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ISA">1ISA</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1ISA">FeMn superoxide dismutase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P09157">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P09157">Fe,Mn superoxide dismutase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2447093">2447093</A></td>
|
||
<td rowspan=3>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.15.1.1"><B>1.15.1.1</B></A></td>
|
||
<td>Superoxide dismutase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P53635">P53635</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P53635">SODC_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ESO">1ESO</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1ESO">Immunoglobulin-like beta-sandwich</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P53635">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P53635">Cu,Zn superoxide dismutase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9405149">9405149</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.15.1.1"><B>1.15.1.1</B></A></td>
|
||
<td>Superoxide dismutase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P80734">P80734</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P80734">SODN_STRSO</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1Q0D">1Q0D</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1Q0D">Four-helical up-and-down bundle</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P80734">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P80734">Nickel superoxide dismutase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15173586">15173586</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>29</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.16.3.1"><B>1.16.3.1</B></A></td>
|
||
<td>Ferroxidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P02794">P02794</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P02794">FRIH_HUMAN</A>, <A href="http://www.uniprot.org/uniprot/P0A998">FTNA_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2CEI">2CEI</A>, <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1BCF">1BCF</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2CEI">Ferritin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P02794">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P02794">Ferritin, Ferritin-like domain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7982945,15201052">7982945, 15201052</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.16.3.1"><B>1.16.3.1</B></A></td>
|
||
<td>Ferroxidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P00450">P00450</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P00450">CERU_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1KCW">1KCW</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1KCW">Cupredoxin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P00450">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P00450">Multicopper oxidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/17242517,12055353">17242517, 12055353</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>30</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.18.1.2"><B>1.18.1.2</B></A></td>
|
||
<td>Ferredoxin-NADP<sup>+</sup> reductase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q44532">Q44532</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q44532">FENR_AZOVI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1A8P">1A8P</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1A8P">Reductase/isomerase/elongation factor common domain and Ferredoxin reductase-like C-terminal NADP-linked domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q44532">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q44532">Oxidoreductase FAD-binding and NAD-binding domains</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8034707,9865948,9149148,8449868">8034707, 9865948, 9149148, 8449868</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.18.1.2"><B>1.18.1.2</B></A></td>
|
||
<td>Ferredoxin-NADP<sup>+</sup> reductase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O05783">O05783</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O05783">FPRA_MYCTU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1LQT">1LQT</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1LQT">FAD/NADP-binding domain and Nucleotide-binding domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O05783">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O05783">Pyridine nucleotide-disulphide oxidoreductase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12071965">12071965</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>31</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.20.4.1"><B>1.20.4.1</B></A></td>
|
||
<td>Arsenate reductase (glutaredoxin)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P08692">P08692</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P08692">ARSC1_ECOLX</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1I9D">1I9D</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1I9D">Thioredoxin fold</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P08692">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P08692">ArsC family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11709171">11709171</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.20.4.1"><B>1.20.4.1</B></A></td>
|
||
<td>Arsenate reductase (glutaredoxin)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q06597">Q06597</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q06597">ACR2_YEAST</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1C25">1C25</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1C25">Rhodanese/Cell cycle control phosphatase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q06597">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q06597">Rhodanese</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10801893">10801893</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>32</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.1.1.43"><B>2.1.1.43</B></A></td>
|
||
<td>Histone-lysine N-methyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q8WTS6">Q8WTS6</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q8WTS6">SETD7_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1N6C">1N6C</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1N6C">Beta-clip</A> (catalytic domain)</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q8WTS6">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q8WTS6">Histone-lysine methyltransferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12540855,12372304">12540855, 12372304</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.1.1.43"><B>2.1.1.43</B></A></td>
|
||
<td>Histone-lysine N-methyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q04089">Q04089</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q04089">DOT1_YEAST</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1U2Z">1U2Z</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1U2Z">S-adenosyl-L-methionine-dependent methyltransferases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q04089">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q04089">Histone methylation protein</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15292170,12086673,12080090">15292170, 12086673, 12080090</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>33</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.1.28"><B>2.3.1.28</B></A></td>
|
||
<td>Chloramphenicol O-acetyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P23364">P23364</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P23364">CAT4_AGRTU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1XAT">1XAT</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1XAT">Single-stranded left-handed beta-helix</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P23364">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P23364">Galactoside acetyltransferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2013403,9578552">2013403, 9578552</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.1.28"><B>2.3.1.28</B></A></td>
|
||
<td>Chloramphenicol O-acetyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P00484">P00484</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P00484">CAT3_ECOLX</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3CLA">3CLA</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=3CLA">CoA-dependent acyltransferases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P00484">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P00484">Chloramphenicol acetyltransferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2187098">2187098</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>34</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.2.5"><B>2.3.2.5</B></A></td>
|
||
<td>Glutaminyl-peptide cyclotransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q16769">Q16769</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q16769">QPCT_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2AFM">2AFM</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2AFM">Phosphorylase/hydrolase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q16769">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q16769">Peptidase family M28</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16135565,15063747">16135565, 15063747</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.2.5"><B>2.3.2.5</B></A></td>
|
||
<td>Glutaminyl-peptide cyclotransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O81226">O81226</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O81226">O81226_CARPA</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2FAW">2FAW</A>, similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1VKD">1VKD</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1VKD">5-bladed beta-propeller ( paper)</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O81226">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O81226">Glutamine cyclotransferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11035947,17081122">11035947, 17081122</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>35</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.4.1.25"><B>2.4.1.25</B></A></td>
|
||
<td>4-alpha-glucanotransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P15977">P15977</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P15977">MALQ_ECOLI</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1FP8">1FP8</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1FP8">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P15977">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P15977">Glycoside hydrolase family 77</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2845225">2845225</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.4.1.25"><B>2.4.1.25</B></A></td>
|
||
<td>4-alpha-glucanotransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O32462">O32462</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O32462">MALQ_THELI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1K1X">1K1X</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1K1X">7-stranded beta/alpha barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O32462">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O32462">Glycosyl hydrolase family 57</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12618437">12618437</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>36</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.5.1.3"><B>2.5.1.3</B></A></td>
|
||
<td>Thiamine-phosphate synthase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P30137">P30137</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P30137">THIE_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2TPS">2TPS</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2TPS">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P30137">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P30137">Thiamine monophosphate synthase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10350464">10350464</A></td>
|
||
<td rowspan=2 bgColor=#ffff00>Two distinct structural folds (no EC)</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.5.1.3"><B>2.5.1.3</B></A></td>
|
||
<td>Thiamine-phosphate synthase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O26949">O26949</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O26949">O26949_METTH</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2PHP">2PHP</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2PHP">AraD/HMP-PK domain-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O26949">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O26949">Archaeal phosphomethylpyrimidine kinase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12794638">12794638</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>37</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.5.1.17"><B>2.5.1.17</B></A></td>
|
||
<td>Cob(I)yrinic acid a,c-diamide adenosyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P31570">P31570</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P31570">BTUR_SALTY</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1G5T">1G5T</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1G5T">P-loop containing NTPases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P31570">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P31570">ATP:corrinoid adenosyltransferase BtuR/CobO/CobP</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7860601">7860601</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.5.1.17"><B>2.5.1.17</B></A></td>
|
||
<td>Cob(I)yrinic acid a,c-diamide adenosyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q96EY8">Q96EY8</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q96EY8">MMAB_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2IDX">2IDX</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1RTY">Ferritin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q96EY8">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q96EY8">Cobalamin adenosyltransferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12514191,17176040">12514191, 17176040</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>38</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.5.1.18"><B>2.5.1.18</B></A></td>
|
||
<td>Glutathione transferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P39100">P39100</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P39100">GST_ECOLI</A>, <A href="http://www.uniprot.org/uniprot/Q9Y2Q3">GSTK1_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1A0F">1A0F</A>, <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1R4W">1R4W</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1A0F">Thioredoxin fold and GST C-terminal domain-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P39100">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P39100">Glutathione S-transferase, class beta, class kappa</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2185038,16081649,14717589">2185038, 16081649, 14717589</A></td>
|
||
<td rowspan=3>Three distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.5.1.18"><B>2.5.1.18</B></A></td>
|
||
<td>Glutathione transferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P10620">P10620</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P10620">MGST1_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2H8A">2H8A</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2H8A">MAPEG domain-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P10620">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P10620">MAPEG family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8812420,9278457,10091672,16806268">8812420, 9278457, 10091672, 16806268</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.5.1.18"><B>2.5.1.18</B></A></td>
|
||
<td>Glutathione transferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q56415">Q56415</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q56415">FOSA_SERMA</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1NPB">1NPB</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1NPB">Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q56415">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q56415">Antibiotic resistance proteins</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15075406,9115979">15075406, 9115979</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>39</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.5.1.47"><B>2.5.1.47</B></A></td>
|
||
<td>Cysteine synthase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P47998">P47998</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P47998">CYSK1_ARATH</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1Z7W">1Z7W</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1Z7W">Tryptophan synthase beta subunit-like PLP-dependent enzymes</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P47998">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P47998">Pyridoxal-phosphate dependent enzyme</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16166087">16166087</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.5.1.47"><B>2.5.1.47</B></A></td>
|
||
<td>Cysteine synthase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P06106">P06106</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P06106">MET17_YEAST</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1GC0">1GC0</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1GC0">PLP-dependent transferase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P06106">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P06106">Cys/Met metabolism PLP-dependent enzyme</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7765825,8511969">7765825, 8511969</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>40</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.1.4"><B>2.7.1.4</B></A></td>
|
||
<td>Fructokinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P40713">P40713</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P40713">SCRK_ECOLI</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1TZ6">1TZ6</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1TZ6">Ribokinase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P40713">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P40713">PfkB family carbohydrate kinase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8278523">8278523</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.1.4"><B>2.7.1.4</B></A></td>
|
||
<td>Fructokinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q07211">Q07211</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q07211">SCRK_STRMU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1XC3">1XC3</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1XC3">Ribonuclease H-like motif</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q07211">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q07211">Actin-like ATPase domain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8336109">8336109</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>41</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.1.11"><B>2.7.1.11</B></A></td>
|
||
<td>6-phosphofructokinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P06998">P06998</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P06998">K6P1_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1PFK">1PFK</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1PFK">Phosphofructokinase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P06998">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P06998">Phosphofructokinase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2975709">2975709</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.1.11"><B>2.7.1.11</B></A></td>
|
||
<td>6-phosphofructokinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P06999">P06999</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P06999">K6PF2_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3CQD">3CQD</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2ABQ">Ribokinase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P06999">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P06999">PfkB family carbohydrate kinase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/18762190,6310120">18762190, 6310120</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>42</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.1.12"><B>2.7.1.12</B></A></td>
|
||
<td>Gluconokinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P46859">P46859</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P46859">GNTK_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1KNQ">1KNQ</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1KNQ">P-loop containing NTPases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P46859">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P46859">Gluconate kinase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8655507,11468405">8655507, 11468405</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.1.12"><B>2.7.1.12</B></A></td>
|
||
<td>Gluconokinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P12011">P12011</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P12011">GNTK_BACSU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3GBT">3GBT</A>, <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2ITM">2ITM</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1R59">Ribonuclease H-like motif</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P12011">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P12011">Glycerol kinase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3020045">3020045</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>43</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.1.31"><B>2.7.1.31</B></A></td>
|
||
<td>Glycerate kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P23524">P23524</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P77364">GLXK2_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1TO6">1TO6</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1TO6">Glycerate kinase I</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P77364">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P77364">Glycerate kinase type-1</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/5325263,166273">5325263, 166273</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.1.31"><B>2.7.1.31</B></A></td>
|
||
<td>Glycerate kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q944I4">Q944I4</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q944I4">GLYK_ARATH</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ODF">1ODF</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1ODF">P-loop containing NTPases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q944I4">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q944I4">GLYK kinase family (UniProt)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15980259">15980259</A></td>
|
||
</TR>
|
||
|
||
<TR bgColor=#ffff00>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.1.31"><I>2.7.1.31</I></A></td>
|
||
<td>Glycerate kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q8IVS8">Q8IVS8</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q8IVS8">GLCTK_HUMAN</A></td>
|
||
<td>smilar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2B8N">2B8N</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2B8N">GckA/TtuD-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q8IVS8">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q8IVS8">Glycerate kinase type-2 (contains MOFRL domain)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16753811,16865707">16753811, 16865707</A></td>
|
||
<td>Produces 2-phospho-glycerate</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>44</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.1.33"><B>2.7.1.33</B></A></td>
|
||
<td>Pantothenate kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O25533">O25533</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O25533">COAX_HELPY</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2NRH">2NRH</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2NRH">Ribonuclease H-like motif</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O25533">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O25533">Type III pantothenate kinase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15795230,16905099">15795230, 16905099</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.1.33"><B>2.7.1.33</B></A></td>
|
||
<td>Pantothenate kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A6I3">P0A6I3</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A6I3">COAA_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1SQ5">1SQ5</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1SQ5">P-loop containing NTPases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A6I3">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A6I3">Phosphoribulokinase/Uridine kinase family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15136582,1328157">15136582, 1328157</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>45</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.1.39"><B>2.7.1.39</B></A></td>
|
||
<td>Homoserine kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P17423">P17423</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P17423">KHSE_YEAST</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1FWK">1FWK</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1FWK">Ribosomal protein S5 domain 2-like and Ferredoxin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P17423">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P17423">GHMP kinase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2165904">2165904</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.1.39"><B>2.7.1.39</B></A></td>
|
||
<td>Homoserine kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P29364">P29364</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P29364">KHSE_PSEAE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2PPQ">2PPQ</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2PPQ">Protein kinase-like (PK-like)</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P29364">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P29364">Phosphotransferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1333566">1333566</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>46</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.1.71"><B>2.7.1.71</B></A></td>
|
||
<td>Shikimate kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A6E1">P0A6E1</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A6E1">AROL_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1SHK">1SHK</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1SHK">P-loop containing NTPases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A6E1">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A6E1">Shikimate kinase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3001029,9600856,11369852">3001029, 9600856, 11369852</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.1.71"><B>2.7.1.71</B></A></td>
|
||
<td>Shikimate kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q58835">Q58835</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q58835">AROK_METJA</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1VIS">1VIS</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1VIS">Ribosomal protein S5 domain 2-like and Ferredoxin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q58835">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q58835">GHMP kinase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11114929">11114929</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>47</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.1.107"><B>2.7.1.107</B></A></td>
|
||
<td>Diacylglycerol kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P49619">P49619</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P49619">DGKG_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2QV7">2QV7</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2QV7">NAD kinase/diacylglycerol kinase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P49619">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P49619">Diacylglycerol kinase catalytic domain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/18611377">18611377</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.1.107"><B>2.7.1.107</B></A></td>
|
||
<td>Diacylglycerol kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0ABN1">P0ABN1</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0ABN1">KDGL_ECOLI</A></td>
|
||
<td>-</td>
|
||
<td>Integral membrane protein</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0ABN1">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0ABN1">Prokaryotic diacylglycerol kinase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2984194,8071224">2984194, 8071224</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>48</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.4.1"><B>2.7.4.1</B></A></td>
|
||
<td>Polyphosphate kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A7B1">P0A7B1</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A7B1">PPK_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1XDO">1XDO</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1XDO">Spectrin repeat-like and Phospholipase D/nuclease and PHP14-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A7B1">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A7B1">Polyphosphate kinase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8380170,1331061">8380170, 1331061</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.4.1"><B>2.7.4.1</B></A></td>
|
||
<td>Polyphosphate kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q8GCQ3">Q8GCQ3</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q8GCQ3">Q8GCQ3_PSEAE</A> (PPK2)</td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3CZQ">3CZQ</A></td>
|
||
<td>3-layer Alpha/beta/alpha sandwich fold (paper), contains P-loop</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q8GCQ3">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q8GCQ3">Polyphosphate kinase 2</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12486232,19001261">12486232, 19001261</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>49</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.4.2"><B>2.7.4.2</B></A></td>
|
||
<td>Phosphomevalonate kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P24521">P24521</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P24521">ERG8_YEAST</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1FWL">1FWL</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1FWL">Ribosomal protein S5 domain 2-like and Ferredoxin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P24521">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P24521">GHMP_kinases</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1846667">1846667</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.4.2"><B>2.7.4.2</B></A></td>
|
||
<td>Phosphomevalonate kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q15126">Q15126</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q15126">PMVK_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3CH4">3CH4</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1DEK">P-loop containing NTPases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q15126">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q15126">Phosphomevalonate kinase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10191291,16519518,17902708">10191291, 16519518, 17902708</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>50</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.10.2"><B>2.7.10.2</B></A></td>
|
||
<td>Non-specific protein-tyrosine kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P06241">P06241</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P06241">FYN_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2H8H">2H8H</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2H8H">Protein kinase-like (PK-like)</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P06241">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P06241">Protein tyrosine kinase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15557120">15557120</A></td>
|
||
<td rowspan=3>At least two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.10.2"><B>2.7.10.2</B></A></td>
|
||
<td>Non-specific protein-tyrosine kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q54520">Q54520</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q54520">CPSD2_STRPN</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1G3Q">1G3Q</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1G3Q">P-loop containing NTPases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q54520">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q54520">CbiA</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10760144">10760144</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.10.2"><B>2.7.10.2</B></A></td>
|
||
<td>Non-specific protein-tyrosine kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9UIG0">Q9UIG0</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9UIG0">BAZ1B_HUMAN</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9UIG0">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9UIG0">Pfam hit</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/19092802">19092802</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>51</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.2"><B>3.1.1.2</B></A></td>
|
||
<td>Arylesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q07792">Q07792</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q07792">ESTE_VIBMI</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1IVN">1IVN</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1IVN">Flavodoxin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q07792">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q07792">GDSL-like Lipase/Acylhydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8141782">8141782</A></td>
|
||
<td rowspan=3>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.2"><B>3.1.1.2</B></A></td>
|
||
<td>Arylesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P22862">P22862</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P22862">ESTE_PSEFL</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1VA4">1VA4</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1VA4">Alpha/beta hydrolase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P22862">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P22862">Alpha/beta hydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15213385,7704276,1368608">15213385, 7704276, 1368608</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.2"><B>3.1.1.2</B></A></td>
|
||
<td>Arylesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P27169">P27169</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P27169">PON1_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1V04">1V04</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1V04">6-bladed beta-propeller</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P27169">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P27169">Arylesterase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8393742,1718413,1673382,15098021">8393742, 1718413, 1673382, 15098021</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>52</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.4"><B>3.1.1.4</B></A></td>
|
||
<td>Phospholipase A2</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9NZK7">Q9NZK7</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9NZK7">PA2GE_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1POE">1POE</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1POE">Phospholipase A2 PLA2</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9NZK7">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9NZK7">Phospholipase A2</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10681567">10681567</A></td>
|
||
<td rowspan=3>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.4"><B>3.1.1.4</B></A></td>
|
||
<td>Phospholipase A2</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A921">P0A921</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A921">PA1_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1QD5">1QD5</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QD5">Transmembrane beta-barrels</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A921">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A921">Phospholipase A1</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8300539,10537112">8300539, 10537112</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.4"><B>3.1.1.4</B></A></td>
|
||
<td>Phospholipase A2</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P47712">P47712</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P47712">PA24A_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1CJY">1CJY</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1CJY">FabD/lysophospholipase-like</A> (catalytic domain)</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P47712">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P47712">Lysophospholipase catalytic domain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10319815,8083230,11416127">10319815, 8083230, 11416127</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>53</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.5"><B>3.1.1.5</B></A></td>
|
||
<td>Lysophospholipase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O88202">O88202</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O88202">LPP60_RAT</A></td>
|
||
<td>N-term is similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2OCD">2OCD</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2OCD">Glutaminase/Asparaginase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O88202">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O88202">Asparaginase (N-term)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9575212">9575212</A></td>
|
||
<td rowspan=3>At least two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.5"><B>3.1.1.5</B></A></td>
|
||
<td>Lysophospholipase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P47712">P47712</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P47712">PA24A_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1CJY">1CJY</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1CJY">FabD/lysophospholipase-like</A> (catalytic domain)</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P47712">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P47712">Lysophospholipase catalytic domain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10319815,8083230,11416127">10319815, 8083230, 11416127</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.5"><B>3.1.1.5</B></A></td>
|
||
<td>Lysophospholipase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P07000">P07000</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P07000">PLDB_ECOLI</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1A8Q">1A8Q</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1A8Q">Alpha/beta hydrolase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P07000">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P07000">Alpha/beta hydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3908447,3908445">3908447, 3908445</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>54</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.29"><B>3.1.1.29</B></A></td>
|
||
<td>Aminoacyl-tRNA hydrolase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A7D1">P0A7D1</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A7D1">PTH_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2PTH">2PTH</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2PTH">Phosphorylase/hydrolase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A7D1">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A7D1">Peptidyl-tRNA hydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9303320">9303320</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.29"><B>3.1.1.29</B></A></td>
|
||
<td>Aminoacyl-tRNA hydrolase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q980V1">Q980V1</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q980V1">PTH_SULSO</A>, <A href="http://www.uniprot.org/uniprot/Q9Y3E5">PTH2_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1XTY">1XTY</A>, <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1Q7S">1Q7S</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1Q7S">Peptidyl-tRNA hydrolase II</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q980V1">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q980V1">Peptidyl-tRNA hydrolase PTH2</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12799450,15766258,14660562">12799450, 15766258, 14660562</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>55</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.31"><B>3.1.1.31</B></A></td>
|
||
<td>6-phosphogluconolactonase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9EV79">Q9EV79</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9EV79">6PGL_PSEPU</A>, <A href="http://www.uniprot.org/uniprot/Q9X0N8">6PGL_THEMA</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1VL1">1VL1</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1VL1">NagB/RpiA/CoA transferase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9EV79">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9EV79">Glucosamine/galactosamine-6-phosphate isomerase (uniprot)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10869070,11277923,16359314">10869070, 11277923, 16359314</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.31"><B>3.1.1.31</B></A></td>
|
||
<td>6-phosphogluconolactonase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P52697">P52697</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P52697">6PGL_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1RI6">1RI6</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1RI6">7-bladed beta-propeller</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P52697">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P52697">Cycloisomerase 2 (uniprot)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15576773,16359314">15576773, 16359314</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>56</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.61"><B>3.1.1.61</B></A></td>
|
||
<td>Protein-glutamate methylesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P07330">P07330</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P07330">CHEB_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1CHD">1CHD</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1CHD">Methylesterase CheB, C-terminal domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P07330">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P07330">CheB methylesterase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7608974">7608974</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.61"><B>3.1.1.61</B></A></td>
|
||
<td>Protein-glutamate methylesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9X005">Q9X005</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9X005">CHED_THEMA</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2F9Z">2F9Z</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2F9Z">CheC-like and CNF1/YfiH-like putative cysteine hydrolases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9X005">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9X005">CheD</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16469702">16469702</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>57</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.2.1"><B>3.1.2.1</B></A></td>
|
||
<td>Acetyl-CoA hydrolase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9UUJ9">Q9UUJ9</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9UUJ9">ACH1_SCHPO</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2G39">2G39</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2G39">NagB/RpiA/CoA transferase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9UUJ9">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9UUJ9">Acetyl-CoA hydrolase/transferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12606555,1970569">12606555, 1970569</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.2.1"><B>3.1.2.1</B></A></td>
|
||
<td>Acetyl-CoA hydrolase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q99NB7">Q99NB7</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q99NB7">ACO12_RAT</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3B7K">3B7K</A> (N-term) <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3FO5">3FO5</A> (C-term)</td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1VPM">Thioesterase/thiol ester dehydrase-isomerase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q99NB7">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q99NB7">Thioesterase superfamily</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11322891">11322891</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=6>58</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.2"><B>3.1.3.2</B></A></td>
|
||
<td>Acid phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9NPH0">Q9NPH0</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9NPH0">PPA6_HUMAN</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ND5">1ND5</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1ND5">Phosphoglycerate mutase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9NPH0">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9NPH0">Histidine acid phosphatase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12010880,10506173">12010880, 10506173</A></td>
|
||
<td rowspan=6>At least five distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.2"><B>3.1.3.2</B></A></td>
|
||
<td>Acid phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0AE22">P0AE22</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0AE22">APHA_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1N8N">1N8N</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1N8N">HAD-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0AE22">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0AE22">Class B acid phosphatases</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9011040">9011040</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.2"><B>3.1.3.2</B></A></td>
|
||
<td>Acid phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P14924">P14924</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P14924">PPA_ZYMMO</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1D2T">1D2T</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1D2T">Acid phosphatase/Vanadium-dependent haloperoxidase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P14924">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P14924">Type 2 phosphatidic acid phosphatase (PAP2)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2914872">2914872</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.2"><B>3.1.3.2</B></A></td>
|
||
<td>Acid phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P13686">P13686</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P13686">PPA5_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1UTE">1UTE</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1UTE">Metallo-dependent phosphatases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P13686">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P13686">Calcineurin-like phosphoesterase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2775236">2775236</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.2"><B>3.1.3.2</B></A></td>
|
||
<td>Acid phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P24666">P24666</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P24666">PPAC_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=5PNT">5PNT</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=5PNT">Phosphotyrosine protein phosphatases I-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P24666">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P24666">Low molecular weight phosphotyrosine protein phosphatase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9705307">9705307</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.2"><B>3.1.3.2</B></A></td>
|
||
<td>Acid phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P37274">P37274</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P37274">PHOA_PENCH</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P37274">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P37274">Phosphoesterase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1563629">1563629</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>59</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.5"><B>3.1.3.5</B></A></td>
|
||
<td>5'-nucleotidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A840">P0A840</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A840">SURE_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1L5X">1L5X</A>, <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2V4O">2V4O</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1L5X">SurE-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A840">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A840">SurE nucleotidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/19021761,15489502">19021761, 15489502</A></td>
|
||
<td rowspan=3>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.5"><B>3.1.3.5</B></A></td>
|
||
<td>5'-nucleotidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/B1X903">B1X903</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/B1X903">YFBR_ECODH</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2PAQ">2PAQ</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2PAQ">HD-domain/PDEase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=B1X903">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/B1X903">Metal dependent phosphohydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15489502">15489502</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.5"><B>3.1.3.5</B></A></td>
|
||
<td>5'-nucleotidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O46411">O46411</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O46411">5NTC_BOVIN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2J2C">2J2C</A>, similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2BDE">2BDE</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2BDE">HAD-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O46411">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O46411">5' nucleotidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9371705">9371705</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>60</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.8"><B>3.1.3.8</B></A></td>
|
||
<td>3-phytase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P42094">P42094</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P42094">PHYT_BACSU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1POO">1POO</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1POO">6-bladed beta-propeller</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P42094">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P42094">Phytase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11104666">11104666</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.8"><B>3.1.3.8</B></A></td>
|
||
<td>3-phytase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O00092">O00092</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O00092">PHYA_ASPFU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1QWO">1QWO</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QWO">Phosphoglycerate mutase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O00092">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O00092">Histidine acid phosphatase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9143104,15136045">9143104, 15136045</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=4>61</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.11"><B>3.1.3.11</B></A></td>
|
||
<td>Fructose-bisphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P19912">P19912</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P19912">F16P2_RALEH</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1D9Q">1D9Q</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1D9Q">Carbohydrate phosphatase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P19912">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P19912">FBPase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7767230">7767230</A></td>
|
||
<td rowspan=4>At least three distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.11"><B>3.1.3.11</B></A></td>
|
||
<td>Fructose-bisphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q45597">Q45597</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q45597">F16P_BACSU</A></td>
|
||
<td>-</td>
|
||
<td>Metallo-dependent phosphatases</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q45597">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q45597">Firmicute fructose-1,6-bisphosphatase (FBPase 2)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/221467,9696785">221467, 9696785</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.11"><B>3.1.3.11</B></A></td>
|
||
<td>Fructose-bisphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q8U359">Q8U359</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q8U359">Q8U359_PYRFU</A> (PF0613)</td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1UMG">1UMG</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1UMG">Sulfolobus fructose-16-bisphosphatase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q8U359">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q8U359">FBPase 3</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12029059,15274916,12065581,15317785">12029059, 15274916, 12065581, 15317785</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.11"><B>3.1.3.11</B></A></td>
|
||
<td>Fructose-bisphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P36136">P36136</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P36136">YK23_YEAST</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3LL4">3LL4</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QHF">Phosphoglycerate mutase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P36136">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q8U359">Phosphoglycerate mutase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/20427268">20427268</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>62</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.15"><B>3.1.3.15</B></A></td>
|
||
<td>Histidinol-phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P06987">P06987</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P06987">HIS7_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2FPR">2FPR</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2FPR">HAD-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P06987">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P06987">Polynucleotide kinase 3 phosphatase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16966333">16966333</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.15"><B>3.1.3.15</B></A></td>
|
||
<td>Histidinol-phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O34411">O34411</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O34411">HIS9_BACSU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3DCP">3DCP</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2ANU">7-stranded beta/alpha barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O34411">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O34411">Polymerase/Histidinol Phosphatase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10322033,17929834">10322033, 17929834</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=4>63</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.16"><B>3.1.3.16</B></A></td>
|
||
<td>Phosphoprotein phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P55798">P55798</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P55798">PRP1_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1G5B">1G5B</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1G5B">Metallo-dependent phosphatases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P55798">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P55798">Calcineurin-like phosphoesterase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9130712">9130712</A></td>
|
||
<td rowspan=4>Four distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.16"><B>3.1.3.16</B></A></td>
|
||
<td>Phosphoprotein phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O34779">O34779</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O34779">PRPC_BACSU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2PK0">2PK0</A>, similar to C-term of <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1TXO">1TXO</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1TXO">PP2C-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O34779">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O34779">Protein phosphatase 2C</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10986276">10986276</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.16"><B>3.1.3.16</B></A></td>
|
||
<td>Phosphoprotein phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9GZU7">Q9GZU7</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9GZU7">CTDS1_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1TA0">1TA0</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1TA0">HAD-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9GZU7">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9GZU7">NLI interacting factor-like phosphatase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15304220">15304220</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.16"><B>3.1.3.16</B></A></td>
|
||
<td>Phosphoprotein phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q8WTR2">Q8WTR2</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q8WTR2">DUS19_HUMAN</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1M3G">1M3G</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1M3G">Phosphotyrosine protein phosphatases II</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q8WTR2">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q8WTR2">Dual specificity phosphatase</A> (catalytic domain)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12479873">12479873</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=4>64</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.33"><B>3.1.3.33</B></A></td>
|
||
<td>Polynucleotide 5'-phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O13297">O13297</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O13297">CET1_YEAST</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1D8H">1D8H</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1D8H">CYTH-like phosphatases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O13297">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O13297">mRNA capping enzyme, beta chain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9345280,10589681">9345280, 10589681</A></td>
|
||
<td rowspan=4>At least two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.33"><B>3.1.3.33</B></A></td>
|
||
<td>Polynucleotide 5'-phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O60942">O60942</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O60942">MCE1_HUMAN</A></td>
|
||
<td>N-term is <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1I9S">1I9S</A> and C-term is similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1P16">1P16</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1I9S">Phosphotyrosine protein phosphatases II</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O60942">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O60942">Dual specificity phosphatase, catalytic domain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9473487,9371772,9512541">9473487, 9371772, 9512541</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.33"><B>3.1.3.33</B></A></td>
|
||
<td>Polynucleotide 5'-phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P04298">P04298</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P04298">MCEL_VACCW</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P04298">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P04298">Viral GTase family (UniProt)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8662636,8662635">8662636, 8662635</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.33"><B>3.1.3.33</B></A></td>
|
||
<td>Polynucleotide 5'-phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P08411">P08411</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P08411">POLN_SFV</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P08411">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P08411">Pfam hits</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10748213">10748213</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=5>65</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.48"><B>3.1.3.48</B></A></td>
|
||
<td>Protein-tyrosine-phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P53433">P53433</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P53433">PTPA_STRCO</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1D1P">1D1P</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1D1P">Phosphotyrosine protein phosphatases I-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P53433">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P53433">Low-molecular-weight phosphotyrosine protein phosphatases</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8550407,1304913">8550407, 1304913</A></td>
|
||
<td rowspan=5>At least three distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.48"><B>3.1.3.48</B></A></td>
|
||
<td>Protein-tyrosine-phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P23468">P23468</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P23468">PTPRD_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1LAR">1LAR</A> (C-term)</td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1LAR">Phosphotyrosine protein phosphatases II</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P23468">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P23468">Higher-molecular-weight phosphotyrosine protein phosphatases</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2170109,8833149">2170109, 8833149</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.48"><B>3.1.3.48</B></A></td>
|
||
<td>Protein-tyrosine-phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P30307">P30307</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P30307">MPIP3_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1QB0">1QB0</A> (C-term)</td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QB0">Rhodanese/Cell cycle control phosphatase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P30307">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P30307">Cell cycle control phosphatase, catalytic domain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8276463">8276463</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.48"><B>3.1.3.48</B></A></td>
|
||
<td>Protein-tyrosine-phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P96717">P96717</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P96717">YWQE_BACSU</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2anu">2anu</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2anu">7-stranded beta/alpha barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P96717">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P96717">PHP domain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15866923">15866923</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.48"><B>3.1.3.48</B></A></td>
|
||
<td>Protein-tyrosine-phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P97480">P97480</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P97480">EYA3_MOUSE</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1jud">1jud</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1jud">HAD-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P97480">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P97480">HAD-like hydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/14628042,14628052">14628042, 14628052</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>66</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.4.52"><B>3.1.4.52</B></A></td>
|
||
<td>Cyclic-diguanylate-specific phosphodiesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P21514">P21514</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P21514">YAHA_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2BAS">2BAS</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2BAS">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P21514">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P21514">Pfam hits</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15994307,15995192">15994307, 15995192</A></td>
|
||
<td rowspan=2 bgColor=#ffff00>Two distinct structural folds (EC 3.1.4.-)</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.4.52"><B>3.1.4.52</B></A></td>
|
||
<td>Cyclic-diguanylate-specific phosphodiesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q4UU85">Q4UU85</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q4UU85">RPFG_XANC8</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1F0J">1F0J</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1F0J">HD-domain/PDEase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q4UU85">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q4UU85">HD domain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16611728">16611728</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>67</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.6.1"><B>3.1.6.1</B></A></td>
|
||
<td>Arylsulfatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P51691">P51691</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P51691">ARS_PSEAE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1HDH">1HDH</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1HDH">Alkaline phosphatase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P51691">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P51691">Sulfatase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7744061,11435113">7744061, 11435113</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.6.1"><B>3.1.6.1</B></A></td>
|
||
<td>Arylsulfatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P28607">P28607</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P28607">ARS_ALTCA</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2CBN">2CBN</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2CBN">Metallo-hydrolase/oxidoreductase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P28607">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P28607">Metallo-beta-lactamase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8535517">8535517</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>68</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.8.1"><B>3.1.8.1</B></A></td>
|
||
<td>Aryldialkylphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A434">P0A434</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A434">OPD_BREDI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1PSC">1PSC</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1PSC">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A434">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A434">Phosphotriesterase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7794910">7794910</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.8.1"><B>3.1.8.1</B></A></td>
|
||
<td>Aryldialkylphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q15165">Q15165</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q15165">PON2_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1V04">1V04</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1V04">6-bladed beta-propeller</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q15165">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q15165">Arylesterase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8661009,11579088,15098021">8661009, 11579088, 15098021</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>69</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.8.2"><B>3.1.8.2</B></A></td>
|
||
<td>Diisopropyl-fluorophosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q7SIG4">Q7SIG4</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q7SIG4">DFPA_LOLVU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2GVV">2GVV</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2GVV">6-bladed beta-propeller</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q7SIG4">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q7SIG4">SMP-30/Gluconolaconase/LRE-like</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11295437,11171055">11295437, 11171055</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.8.2"><B>3.1.8.2</B></A></td>
|
||
<td>Diisopropyl-fluorophosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P77814">P77814</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P77814">PEPQ_PSEHA</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2BWX">2BWX</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2BWX">Creatinase/aminopeptidase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P77814">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P77814">Metallopeptidase family M24</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9079288">9079288</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>70</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.11.2"><B>3.1.11.2</B></A></td>
|
||
<td>Exodeoxyribonuclease III</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P09030">P09030</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P09030">EX3_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1AKO">1AKO</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1AKO">DNase I-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P09030">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P09030">Endonuclease/Exonuclease/phosphatase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7885481,8948651">7885481, 8948651</A></td>
|
||
<td rowspan=3>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.11.2"><B>3.1.11.2</B></A></td>
|
||
<td>Exodeoxyribonuclease III</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9BQ50">Q9BQ50</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9BQ50">TREX2_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1Y97">1Y97</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1Y97">Ribonuclease H-like motif</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9BQ50">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9BQ50">Exonuclease</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15661738,10391904">15661738, 10391904</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.11.2"><B>3.1.11.2</B></A></td>
|
||
<td>Exodeoxyribonuclease III</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O60671">O60671</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O60671">RAD1_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3A1J">3A1J</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1PLQ">DNA clamp</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O60671">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O60671">Repair protein Rad1/Rec1/Rad17</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9660799,9716408">9660799, 9716408</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>71</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.11.3"><B>3.1.11.3</B></A></td>
|
||
<td>Exodeoxyribonuclease (lambda-induced)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P06229">P06229</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P06229">EXO5_BPT5</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1UT5">1UT5</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1UT5">PIN_domain-like</A> (catalytic domain)</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P06229">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P06229">5'3'-exonuclease, N-terminal resolvase-like domain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3002857,9874768">3002857, 9874768</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.11.3"><B>3.1.11.3</B></A></td>
|
||
<td>Exodeoxyribonuclease (lambda-induced)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P03697">P03697</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P03697">EXO_LAMBD</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1AVQ">1AVQ</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1AVQ">Restriction endonuclease-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P03697">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P03697">YqaJ viral recombinase family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9295273">9295273</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>72</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.13.1"><B>3.1.13.1</B></A></td>
|
||
<td>Exoribonuclease II</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P30850">P30850</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P30850">RNB_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2IX0">2IX0</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2IX0">OB-fold</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P30850">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P30850">Ribonuclease II (RNB)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8497196">8497196</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.13.1"><B>3.1.13.1</B></A></td>
|
||
<td>Exoribonuclease II</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q96AZ6">Q96AZ6</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q96AZ6">ISG20_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1WLJ">1WLJ</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1WLJ">Ribonuclease H-like motif</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q96AZ6">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q96AZ6">Exonuclease</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11401564,12594219">11401564, 12594219</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>73</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.21.1"><B>3.1.21.1</B></A></td>
|
||
<td>Deoxyribonuclease I</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P00639">P00639</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P00639">DNAS1_BOVIN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1DNK">1DNK</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1ATN">Ribonuclease H-like motif and DNase I-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P00639">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P00639">Endonuclease/Exonuclease/phosphatase family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9469931">9469931</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.21.1"><B>3.1.21.1</B></A></td>
|
||
<td>Deoxyribonuclease I</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P25736">P25736</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P25736">END1_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1OUP">1OUP</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1OUP">His-Me finger endonucleases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P25736">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P25736">Endonuclease I</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7867949">7867949</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>74</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.21.2"><B>3.1.21.2</B></A></td>
|
||
<td>Deoxyribonuclease IV (phage-T4-induced)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A6C1">P0A6C1</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A6C1">END4_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1QUM">1QUM</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QUM">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A6C1">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A6C1">Xylose isomerase-like TIM barrel (clan)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10458614">10458614</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.21.2"><B>3.1.21.2</B></A></td>
|
||
<td>Deoxyribonuclease IV (phage-T4-induced)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P00641">P00641</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P00641">ENRN_BPT7</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1M0D">1M0D</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1M0D">Restriction endonuclease-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P00641">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P00641">Phage endonuclease I</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12093751">12093751</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>75</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.22.4"><B>3.1.22.4</B></A></td>
|
||
<td>Crossover junction endodeoxyribonuclease</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A814">P0A814</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A814">RUVC_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1HJR">1HJR</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1HJR">Ribonuclease H-like motif</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A814">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A814">RuvC</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7923356,1661673">7923356, 1661673</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.22.4"><B>3.1.22.4</B></A></td>
|
||
<td>Crossover junction endodeoxyribonuclease</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0AG74">P0AG74</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0AG74">RUSA_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1Q8R">1Q8R</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1Q8R">Bacillus chorismate mutase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0AG74">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0AG74">RusA</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/14656440,9169457">14656440, 9169457</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>76</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.26.4"><B>3.1.26.4</B></A></td>
|
||
<td>Calf thymus ribonuclease H</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P10442">P10442</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P10442">RNH2_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2ETJ">2ETJ</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2ETJ">Ribonuclease H-like motif</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P10442">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P10442">RNase HII</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2172991">2172991</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.26.4"><B>3.1.26.4</B></A></td>
|
||
<td>Calf thymus ribonuclease H</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P13319">P13319</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P13319">RNH_BPT4</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1TFR">1TFR</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1TFR">PIN_domain-like</A> (catalytic domain)</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P13319">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P13319">T4 RNase H, C terminal</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1703156,8674116">1703156, 8674116</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>77</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.1"><B>3.2.1.1</B></A></td>
|
||
<td>Alpha-amylase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P25718">P25718</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P25718">AMY1_ECOLI</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1EA9">1EA9</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1EA9">TIM beta/alpha-barrel and Glycosyl hydrolase domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P25718">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P25718">Alpha-amylase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9268356">9268356</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.1"><B>3.2.1.1</B></A></td>
|
||
<td>Alpha-amylase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P49067">P49067</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P49067">AMYA_PYRFU</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1K1X">1K1X</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1K1X">7-stranded beta/alpha barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P49067">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P49067">Glycosyl hydrolase family 57</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8226990">8226990</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=6>78</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.4"><B>3.2.1.4</B></A></td>
|
||
<td>Cellulase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P10476">P10476</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P10476">GUNA_PSEFL</A></td>
|
||
<td>N-term is similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1UT9">1UT9</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1UT9">Alpha/alpha toroid</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P10476">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P10476">Glycosyl hydrolase 9 family (cellulase E)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2851699">2851699</A></td>
|
||
<td rowspan=6>At least four distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.4"><B>3.2.1.4</B></A></td>
|
||
<td>Cellulase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P17901">P17901</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P17901">GUNA_CLOCE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1EDG">1EDG</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1EDG">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P17901">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P17901">Beta-glycanases</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1744052,8535787">1744052, 8535787</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.4"><B>3.2.1.4</B></A></td>
|
||
<td>Cellulase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P33682">P33682</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P33682">GUN1_STRHA</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2BOD">2BOD</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2BOD">7-stranded beta/alpha barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P33682">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P33682">Glycosyl hydrolases family 6</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1400190">1400190</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.4"><B>3.2.1.4</B></A></td>
|
||
<td>Cellulase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P55742">P55742</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P55742">GUNM_CLOTM</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2FVG">2FVG</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2FVG">Phosphorylase/hydrolase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P55742">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P55742">Peptidase M42</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/1097207">GenBank: 1097207</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.4"><B>3.2.1.4</B></A></td>
|
||
<td>Cellulase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P22669">P22669</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P22669">GUN_ASPAC</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1KS4">1KS4</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1KS4">Concanavalin A-like lectins/glucanases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P22669">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P22669">Glycosyl hydrolase 11 family (cellulase G)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2249253,7586029,2379837">2249253, 7586029, 2379837</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.4"><B>3.2.1.4</B></A></td>
|
||
<td>Cellulase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q05622">Q05622</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q05622">GUNE_RUMFL</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1L0H">1L0H</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1L0H">Acyl carrier protein-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q05622">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q05622">Pfam hit</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8360615">8360615</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>79</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.8"><B>3.2.1.8</B></A></td>
|
||
<td>Endo-1,4-<2D>-xylanase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P23551">P23551</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P23551">XYNA_BUTFI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1XAS">1XAS</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1XAS">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P23551">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P23551">Beta-glycanases</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2198249,1909424">2198249, 1909424</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.8"><B>3.2.1.8</B></A></td>
|
||
<td>Endo-1,4-<2D>-xylanase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P33558">P33558</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P33558">XYNA2_CLOSR</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1QH6">1QH6</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QH6">Concanavalin A-like lectins/glucanases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P33558">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P33558">Glycosyl hydrolase 11 family (cellulase G)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7763496">7763496</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>80</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.14"><B>3.2.1.14</B></A></td>
|
||
<td>Chitinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P07254">P07254</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P07254">CHIA_SERMA</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1RD6">1RD6</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1RD6">TIM beta/alpha-barrel</A> (catalytic domain)</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P07254">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P07254">Type II chitinase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16453672">16453672</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.14"><B>3.2.1.14</B></A></td>
|
||
<td>Chitinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P24626">P24626</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P24626">CHI1_ORYSA</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2BAA">2BAA</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2BAA">Lysozyme-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P24626">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P24626">Family 19 glycosidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1893114">1893114</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>81</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.17"><B>3.2.1.17</B></A></td>
|
||
<td>Lysozyme</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P34020">P34020</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P34020">LYS_CLOAB</A></td>
|
||
<td>N-term is similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1JFX">1JFX</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1JFX">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P34020">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P34020">1,4-beta-N-acetylmuraminidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1599233,7649184">1599233, 7649184</A></td>
|
||
<td rowspan=3>At least two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.17"><B>3.2.1.17</B></A></td>
|
||
<td>Lysozyme</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q37875">Q37875</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q37875">LYS_BPP1</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1XJT">1XJT</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1XJT">Lysozyme-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q37875">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q37875">Phage lysozyme</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8576044,9514719">8576044, 9514719</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.17"><B>3.2.1.17</B></A></td>
|
||
<td>Lysozyme</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P10773">P10773</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P10773">LYB_BACSU</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P10773">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P10773">B-enzyme</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3148618">3148618</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>82</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.20"><B>3.2.1.20</B></A></td>
|
||
<td>Alpha-glucosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q02751">Q02751</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q02751">MALT_CANAL</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1JI1">1JI1</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1JI1">TIM beta/alpha-barrel and Glycosyl hydrolase domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q02751">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q02751">Glycosyl hydrolase family 13</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1400249">1400249</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.20"><B>3.2.1.20</B></A></td>
|
||
<td>Alpha-glucosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O33830">O33830</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O33830">AGLA_THEMA</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1OBB">1OBB</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1OBB">Rossmann-fold and LDH C-terminal domain-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O33830">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O33830">Glycosyl hydrolase family 4</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12062450,10972187">12062450, 10972187</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>83</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.22"><B>3.2.1.22</B></A></td>
|
||
<td>Alpha-galactosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P27756">P27756</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P27756">AGAL_STRMU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1R46">1R46</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1R46">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P27756">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P27756">Glycosyl hydrolase family 36</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1649890">1649890</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.22"><B>3.2.1.22</B></A></td>
|
||
<td>Alpha-galactosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P06720">P06720</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P06720">AGAL_ECOLI</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1OBB">1OBB</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1OBB">Rossmann-fold and LDH C-terminal domain-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P06720">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P06720">Glycosyl hydrolase family 4</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2831880">2831880</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>84</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.35"><B>3.2.1.35</B></A></td>
|
||
<td>Hyaluronoglucosaminidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q12891">Q12891</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q12891">HYAL2_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1FCQ">1FCQ</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1FCQ">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q12891">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q12891">Glycosyl hydrolase family 56</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9712871,17503783">9712871, 17503783</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.35"><B>3.2.1.35</B></A></td>
|
||
<td>Hyaluronoglucosaminidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q54699">Q54699</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q54699">HYLP2_BPH45</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2PK1">2PK1</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2PK1">Triple-stranded beta-helix</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q54699">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q54699">Hyaluronidase_1</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7622224">7622224</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>85</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.37"><B>3.2.1.37</B></A></td>
|
||
<td>Xylan 1,4-<2D>-xylosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P07129">P07129</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P07129">XYNB_BACPU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1YIF">1YIF</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1YIF">5-bladed beta-propeller</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P07129">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P07129">Glycosyl hydrolase family 43</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2440680,7766665">2440680, 7766665</A></td>
|
||
<td rowspan=3>At least two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.37"><B>3.2.1.37</B></A></td>
|
||
<td>Xylan 1,4-<2D>-xylosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P36906">P36906</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P36906">XYNB_THESA</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1PX8">1PX8</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1PX8">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P36906">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P36906">Glycosyl hydrolase family 39</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8612648">8612648</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.37"><B>3.2.1.37</B></A></td>
|
||
<td>Xylan 1,4-<2D>-xylosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P45702">P45702</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P45702">XYLA1_BACST</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P45702">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P45702">Glycosyl hydrolase family 52</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8074507,11322943">8074507, 11322943</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>86</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.39"><B>3.2.1.39</B></A></td>
|
||
<td>Glucan endo-1,3-<2D>-D-glucosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P33157">P33157</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P33157">E13A_ARATH</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2CYG">2CYG</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2CYG">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P33157">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P33157">Glycosyl hydrolase family 17</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11405630,16421930">11405630, 16421930</A></td>
|
||
<td rowspan=3>At least two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.39"><B>3.2.1.39</B></A></td>
|
||
<td>Glucan endo-1,3-<2D>-D-glucosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P23903">P23903</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P23903">E13B_BACCI</A></td>
|
||
<td>C-term is <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2VY0">2VY0</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1UPS">Concanavalin A-like lectins/glucanases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P23903">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P23903">Glycosyl hydrolase family 16</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2311931,19154353">2311931, 19154353</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.39"><B>3.2.1.39</B></A></td>
|
||
<td>Glucan endo-1,3-<2D>-D-glucosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P22222">P22222</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P22222">E13B_CELCE</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P22222">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P22222">Glycosyl hydrolase family 64</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1985933">1985933</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>87</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.49"><B>3.2.1.49</B></A></td>
|
||
<td>Alpha-N-acetylgalactosaminidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P17050">P17050</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P17050">NAGAB_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3H53">3H53</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=3H53">TIM beta/alpha-barrel and Glycosyl hydrolase domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P17050">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P17050">Melibiase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/19683538">19683538</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.49"><B>3.2.1.49</B></A></td>
|
||
<td>Alpha-N-acetylgalactosaminidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/A4Q8F7">A4Q8F7</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/A4Q8F7">GH109_FLAME</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2IXA">2IXA</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2IXA">Rossmann-fold</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=A4Q8F7">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/A4Q8F7">Oxidoreductase family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/17401360">17401360</A></td>
|
||
</TR>
|
||
|
||
|
||
<TR>
|
||
<td center rowspan=2>88</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.55"><B>3.2.1.55</B></A></td>
|
||
<td>Alpha-N-arabinofuranosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P53627">P53627</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P53627">ABFA_STRLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2C7F">2C7F</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2C7F">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P53627">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P53627">Glycosyl hydrolase family 51</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8092996,16336192">8092996, 16336192</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.55"><B>3.2.1.55</B></A></td>
|
||
<td>Alpha-N-arabinofuranosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P45982">P45982</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P45982">XYLB_BUTFI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1YRZ">1YRZ</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1YRZ">5-bladed beta-propeller and Concanavalin A-like lectins/glucanases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P45982">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P45982">Glycosyl hydrolase family 43</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1905520,18980579">1905520, 18980579</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>89</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.73"><B>3.2.1.73</B></A></td>
|
||
<td>Licheninase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P07979">P07979</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P07979">GUB_NICPL</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2CYG">2CYG</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2CYG">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P07979">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P07979">Glycosyl hydrolase family 17</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9452466">9452466</A></td>
|
||
<td rowspan=3>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.73"><B>3.2.1.73</B></A></td>
|
||
<td>Licheninase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P04957">P04957</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P04957">GUB_BACSU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1GBG">1GBG</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1GBG">Concanavalin A-like lectins/glucanases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P04957">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P04957">Glycosyl hydrolase family 16</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1740123">1740123</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.73"><B>3.2.1.73</B></A></td>
|
||
<td>Licheninase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P19254">P19254</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P19254">GUB_BACCI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1V5C">1V5C</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1V5C">Alpha/alpha toroid</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P19254">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P19254">Glycosyl hydrolase family 8 (cellulase D)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2377467">2377467</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>90</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.86"><B>3.2.1.86</B></A></td>
|
||
<td>6-phospho-<2D>-glucosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P11988">P11988</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P11988">BGLB_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1QOX">1QOX</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QOX">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P11988">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P11988">Glycosyl hydrolase family 1</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3034860">3034860</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.86"><B>3.2.1.86</B></A></td>
|
||
<td>6-phospho-<2D>-glucosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P17411">P17411</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P17411">CHBF_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1S6Y">1S6Y</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1S6Y">Rossmann-fold and LDH C-terminal domain-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P17411">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P17411">Glycosyl hydrolase family 4</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10572139">10572139</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>91</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.91"><B>3.2.1.91</B></A></td>
|
||
<td>Cellulose 1,4-<2D>-cellobiosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0C2S1">P0C2S1</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0C2S1">CELK_CLOTM</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1UT9">1UT9</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1UT9">Alpha/alpha toroid</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0C2S1">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0C2S1">Glycosyl hydrolase 9 (cellulase E) family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10464199">10464199</A></td>
|
||
<td rowspan=3>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.91"><B>3.2.1.91</B></A></td>
|
||
<td>Cellulose 1,4-<2D>-cellobiosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P50401">P50401</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P50401">GUXA_CELFI</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1BVW">1BVW</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1BVW">7-stranded beta/alpha barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P50401">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P50401">Glycosyl hydrolase 6 (cellulase B) family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8065260">8065260</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.91"><B>3.2.1.91</B></A></td>
|
||
<td>Cellulose 1,4-<2D>-cellobiosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P07986">P07986</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P07986">GUX_CELFI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1FH7">1FH7</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1FH7">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P07986">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P07986">Glycosyl hydrolase 10 (cellulase F) family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9537990">9537990</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>92</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.2.21"><B>3.2.2.21</B></A></td>
|
||
<td>DNA-3-methyladenine glycosylase II</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P04395">P04395</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P04395">3MG2_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1MPG">1MPG</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1MPG">DNA-glycosylase and TBP-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P04395">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P04395">AlkA N-terminal domain and HhH-GPD</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/6389535">6389535</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.2.21"><B>3.2.2.21</B></A></td>
|
||
<td>DNA-3-methyladenine glycosylase II</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P29372">P29372</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P29372">3MG_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1F4R">1F4R</A> (C-term)</td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1F4R">FMT C-terminal domain-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P29372">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P29372">Methylpurine-DNA glycosylase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8589517,1645538">8589517, 1645538</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>93</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.1.1"><B>3.5.1.1</B></A></td>
|
||
<td>Asparaginase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P38986">P38986</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P38986">ASPG1_YEAST</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1HFW">1HFW</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1WSA">Glutaminase/Asparaginase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P38986">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P38986">Glutaminase/Asparaginase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8026756">8026756</A></td>
|
||
<td rowspan=3>At least two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.1.1"><B>3.5.1.1</B></A></td>
|
||
<td>Asparaginase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P20933">P20933</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P20933">ASPG_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1APY">1APY</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1APY">Ntn hydrolase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P20933">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P20933">(Glycosyl)asparaginase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1840528">1840528</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.1.1"><B>3.5.1.1</B></A></td>
|
||
<td>Asparaginase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9RFN5">Q9RFN5</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9RFN5">Q9RFN5_RHIET</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9RFN5">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9RFN5">L-asparaginase II</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10930734">10930734</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>94</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.1.4"><B>3.5.1.4</B></A></td>
|
||
<td>Amidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P27765">P27765</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P27765">AMID_PSECL</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1OCK">1OCK</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2F2A">Amidase signature</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P27765">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P27765">Amidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2013568">2013568</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.1.4"><B>3.5.1.4</B></A></td>
|
||
<td>Amidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P11436">P11436</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P11436">ALAM_PSEAE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2UXY">2UXY</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1FO6">Carbon-nitrogen hydrolase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P11436">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P11436">Carbon-nitrogen hydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/87219101">87219101</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>95</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.1.9"><B>3.5.1.9</B></A></td>
|
||
<td>Arylformamidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q8K4H1">Q8K4H1</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q8K4H1">AFMID_MOUSE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2PBL">2PBL</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2PBL">Alpha/beta hydrolase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q8K4H1">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q8K4H1">Pfam hit</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12007602,15935693">12007602, 15935693</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.1.9"><B>3.5.1.9</B></A></td>
|
||
<td>Arylformamidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0C8P4">P0C8P4</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0C8P4">KYNB_RALME</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1R61">1R61</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1R61">The "swivelling" beta/beta/alpha domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0C8P4">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0C8P4">Putative cyclase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/14592712,14592712">14592712, 14592712</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>96</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.1.49"><B>3.5.1.49</B></A></td>
|
||
<td>Formamidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q50228">Q50228</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q50228">FMDA_METME</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2F4L">2F4L</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2F4L">CUB-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q50228">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q50228">Acetamidase/formamidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8841393">8841393</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.1.49"><B>3.5.1.49</B></A></td>
|
||
<td>Formamidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O25836">O25836</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O25836">AMIF_HELPY</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2DYU">2DYU</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1J31">Carbon-nitrogen hydrolase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O25836">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O25836">Carbon-nitrogen hydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11359566,17307742,14742519">11359566, 17307742, 14742519</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>97</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.1.52"><B>3.5.1.52</B></A></td>
|
||
<td>Peptide-N4-(N-acetyl-<2D>-glucosaminyl)asparagine amidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q02890">Q02890</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q02890">PNG1_YEAST</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1X3W">1X3W</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1X3W">Cysteine proteinases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q02890">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q02890">Transglutaminase-like</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10831608,11259433,14726951,15964983">10831608, 11259433, 14726951, 15964983</A></td>
|
||
<td rowspan=3>At least two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.1.52"><B>3.5.1.52</B></A></td>
|
||
<td>Peptide-N4-(N-acetyl-<2D>-glucosaminyl)asparagine amidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P21163">P21163</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P21163">PNGF_ELIMR</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1PNG">1PNG</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1PNG">Nucleoplasmin-like/VP</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P21163">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P21163">Peptide-N-glycosidase F</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7918386,7493989">7918386, 7493989</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.1.52"><B>3.5.1.52</B></A></td>
|
||
<td>Peptide-N4-(N-acetyl-<2D>-glucosaminyl)asparagine amidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P81898">P81898</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P81898">PNAA_PRUDU</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P81898">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P81898">Patent US 5710016 (GenBank AAC20834)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9523720">9523720</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>98</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.2.6"><B>3.5.2.6</B></A></td>
|
||
<td><EFBFBD>-lactamase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P00811">P00811</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P00811">AMPC_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2BLS">2BLS</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2BLS">Beta-lactamase/transpeptidase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P00811">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P00811">Beta-Lactamase/D-ala carboxypeptidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/6795623">6795623</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.2.6"><B>3.5.2.6</B></A></td>
|
||
<td><EFBFBD>-lactamase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P14488">P14488</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P14488">BLAB_BACCE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1BC2">1BC2</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1BC2">Metallo-hydrolase/oxidoreductase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P14488">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P14488">Zn metallo-beta-lactamase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9730812">9730812</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>99</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.2.17"><B>3.5.2.17</B></A></td>
|
||
<td>Hydroxyisourate hydrolase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O32142">O32142</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O32142">HIUH_BACSU</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1OO2">1OO2</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1OO2">Prealbumin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O32142">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O32142">HIUase/Transthyretin</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16098976,16782815">16098976, 16782815</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.2.17"><B>3.5.2.17</B></A></td>
|
||
<td>Hydroxyisourate hydrolase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q8S3J3">Q8S3J3</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q8S3J3">HIUH_SOYBN</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1cbg">1cbg</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1cbg">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q8S3J3">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q8S3J3">Glycosyl hydrolase family 1</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10567345,12481089">10567345, 12481089</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>100</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.4.1"><B>3.5.4.1</B></A></td>
|
||
<td>Cytosine deaminase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P25524">P25524</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P25524">CODA_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1R9Z">1R9Z</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1R9Z">TIM beta/alpha-barrel</A> (catalytic domain)</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P25524">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P25524">Amidohydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11812140,1640834">11812140, 1640834</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.4.1"><B>3.5.4.1</B></A></td>
|
||
<td>Cytosine deaminase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q12178">Q12178</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q12178">FCY1_YEAST</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1P6O">1P6O</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1P6O">Cytidine deaminase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q12178">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q12178">Cytidine and deoxycytidylate deaminase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9000374">9000374</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>101</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.4.3"><B>3.5.4.3</B></A></td>
|
||
<td>Guanine deaminase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P76641">P76641</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P76641">GUAD_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2UZ9">2UZ9</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2UZ9">TIM beta/alpha-barrel</A> (catalytic domain)</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P76641">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P76641">Amidohydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10913105">10913105</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.4.3"><B>3.5.4.3</B></A></td>
|
||
<td>Guanine deaminase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O34598">O34598</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O34598">GUAD_BACSU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1WKQ">1WKQ</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1WKQ">Cytidine deaminase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O34598">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O34598">Cytidine and deoxycytidylate deaminase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15159585,15180998,11101664">15159585, 15180998, 11101664</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>102</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.4.9"><B>3.5.4.9</B></A></td>
|
||
<td>Methenyltetrahydrofolate cyclohydrolase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P24186">P24186</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P24186">FOLD_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1B0A">1B0A</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1B0A">Aminoacid dehydrogenase-like N-terminal domain and Rossmann-fold</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P24186">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P24186">Tetrahydrofolate dehydrogenase/cyclohydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1748668,10386884">1748668, 10386884</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.4.9"><B>3.5.4.9</B></A></td>
|
||
<td>Methenyltetrahydrofolate cyclohydrolase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q49135">Q49135</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q49135">FCHA_METEA</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1O5H">1O5H</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1O5H">Methenyltetrahydrofolate cyclohydrolase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q49135">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q49135">Formiminotransferase-cyclodeaminase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10215859">10215859</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>103</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.4.10"><B>3.5.4.10</B></A></td>
|
||
<td>IMP cyclohydrolase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P31939">P31939</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P31939">PUR9_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1PKX">1PKX</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1P4R">Methylglyoxal synthase-like (IMP cyclohydrolase domain )</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P31939">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P31939">AICARFT/IMPCHase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8567683,14756553,14966129">8567683, 14756553, 14966129</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.4.10"><B>3.5.4.10</B></A></td>
|
||
<td>IMP cyclohydrolase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/A0B9N7">A0B9N7</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/A0B9N7">PURO_METTP</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2NTK">2NTK</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2NTK">Ntn hydrolase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=A0B9N7">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/A0B9N7">IMP cyclohydrolase-like (archaeal )</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/17407260,12012346">17407260, 12012346</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>104</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.99.6"><B>3.5.99.6</B></A></td>
|
||
<td>Glucosamine-6-phosphate deaminase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A759">P0A759</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A759">NAGB_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1FS5">1FS5</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1FS5">NagB/RpiA/CoA transferase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A759">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A759">Glucosamine_iso</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1734962, 8747459">1734962, 8747459</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.99.6"><B>3.5.99.6</B></A></td>
|
||
<td>Glucosamine-6-phosphate deaminase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q5JDU3">Q5JDU3</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q5JDU3">Q5JDU3_PYRKO</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2CB0">2CB0</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1J5X">SIS domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q5JDU3">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q5JDU3">SIS domain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16199574, 16857666, 17387737">16199574, 16857666, 17387737</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=4>105</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.1"><B>3.6.1.1</B></A></td>
|
||
<td>Inorganic diphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P21216">P21216</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P21216">IPYR_ARATH</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1TWL">1TWL</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1TWL">OB-fold</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P21216">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P21216">Pyrophosphatase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/654155">654155</A></td>
|
||
<td rowspan=4>At least three distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.1"><B>3.6.1.1</B></A></td>
|
||
<td>Inorganic diphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P31414">P31414</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P31414">AVP1_ARATH</A></td>
|
||
<td>-</td>
|
||
<td>Integral membrane protein</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P31414">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P31414">Inorganic H<sup>+</sup> pyrophosphatase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9268385">9268385</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.1"><B>3.6.1.1</B></A></td>
|
||
<td>Inorganic diphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P37487">P37487</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P37487">PPAC_BACSU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1WPM">1WPM</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1WPM">DHH phosphoesterases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P37487">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P37487">Mn-dependent inorganic pyrophosphatase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9845334,11697905">9845334, 11697905</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.1"><B>3.6.1.1</B></A></td>
|
||
<td>Inorganic diphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9JMQ2">Q9JMQ2</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9JMQ2">PPAX_BACSU</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2HDO">2HDO</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2HDO">HAD-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9JMQ2">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9JMQ2">HAD-like hydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12359880">12359880</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>106</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.5"><B>3.6.1.5</B></A></td>
|
||
<td>Apyrase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O96559">O96559</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O96559">APY_CIMLE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2H2N">2H2N</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2H2N">5-bladed beta-propeller</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O96559">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O96559">Apyrase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9804829,15006348">9804829, 15006348</A></td>
|
||
<td rowspan=3>At least two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.5"><B>3.6.1.5</B></A></td>
|
||
<td>Apyrase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P50635">P50635</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P50635">APY_AEDAE</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2Z1A">2Z1A</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1HP1">5-nucleotidase and Metallo-dependent phosphatases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P50635">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P50635">5'-nucleotidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2173922">2173922</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.5"><B>3.6.1.5</B></A></td>
|
||
<td>Apyrase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O75355">O75355</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O75355">ENTP3_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3CJ1">3CJ1</A>, similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1T6C">1T6C</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1T6C">Ribonuclease H-like motif</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O75355">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O75355">Actin-like ATPase domain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9675246,8955160">9675246, 8955160</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>107</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.11"><B>3.6.1.11</B></A></td>
|
||
<td>Exopolyphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P29014">P29014</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P29014">PPX_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1U6Z">1U6Z</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1U6Z">Ribonuclease H-like motif and HD-domain/PDEase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P29014">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P29014">Ppx associated domain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8212131">8212131</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.11"><B>3.6.1.11</B></A></td>
|
||
<td>Exopolyphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P38698">P38698</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P38698">PPX1_YEAST</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2QB6">2QB6</A>, similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1K20">1K20</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1K20">DHH phosphoesterases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P38698">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P38698">Mn-dependent inorganic pyrophosphatase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7860598">7860598</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>108</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.13"><B>3.6.1.13</B></A></td>
|
||
<td>ADP-ribose diphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O94759">O94759</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O94759">TRPM2_HUMAN</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1QVJ">1QVJ</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QVJ">NUDIX</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O94759">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O94759">NUDIX domain (paper)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11385575">11385575</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.13"><B>3.6.1.13</B></A></td>
|
||
<td>ADP-ribose diphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q5M886">Q5M886</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q5M886">ADPRM_RAT</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2NXF">2NXF</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2NXF">Metallo-dependent phosphatases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q5M886">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q5M886">Calcineurin-like phosphoesterase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/18352857">18352857</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>109</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.17"><B>3.6.1.17</B></A></td>
|
||
<td>Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P49776">P49776</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P49776">APH1_SCHPO</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1FHI">1FHI</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1FHI">HIT-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P49776">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P49776">HIT family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8554540">8554540</A></td>
|
||
<td rowspan=3>At least two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.17"><B>3.6.1.17</B></A></td>
|
||
<td>Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P50583">P50583</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P50583">AP4A_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1XSA">1XSA</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1XSA">NUDIX</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P50583">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P50583">MutT-like</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7487923">7487923</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.17"><B>3.6.1.17</B></A></td>
|
||
<td>Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O31614">O31614</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O31614">PRPE_BACSU</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1G5B">1G5B</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1G5B">Metallo-dependent phosphatases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O31614">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O31614">Protein serine/threonine phosphatase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12059787">12059787</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>110</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.23"><B>3.6.1.23</B></A></td>
|
||
<td>DUTP diphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P33316">P33316</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P33316">DUT_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1Q5H">1Q5H</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1Q5H">Beta-clip</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P33316">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P33316">dUTPase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8805593,8631816">8805593, 8631816</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.23"><B>3.6.1.23</B></A></td>
|
||
<td>DUTP diphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O15923">O15923</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O15923">O15923_TRYCR</A> (DUT)</td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1OGK">1OGK</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1OGK">all-alpha NTP pyrophosphatases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O15923">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O15923">dUTPase_2</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/14725764,12208522">14725764, 12208522</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>111</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.45"><B>3.6.1.45</B></A></td>
|
||
<td>UDP-sugar diphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P07024">P07024</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P07024">USHA_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2USH">2USH</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2USH">Metallo-dependent phosphatases and 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P07024">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P07024">5'-nucleotidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11491293,10331872">11491293, 10331872</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.45"><B>3.6.1.45</B></A></td>
|
||
<td>UDP-sugar diphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O95848">O95848</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O95848">NUD14_HUMAN</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1VIU">1VIU</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1VIU">NUDIX</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O95848">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O95848">NUDIX hydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12429023">12429023</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>112</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.8.1.3"><B>3.8.1.3</B></A></td>
|
||
<td>Haloacetate dehalogenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q01398">Q01398</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q01398">DEH1_MORSB</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1G5F">1G5F</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1G5F">Alpha/beta hydrolase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q01398">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q01398">Haloalkane dehalogenase; pdb and 1IZ7, pdb and 1MJ5</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1512562,11939779">1512562, 11939779</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.8.1.3"><B>3.8.1.3</B></A></td>
|
||
<td>Haloacetate dehalogenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q01399">Q01399</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q01399">DEH2_MORSB</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1JUD">1JUD</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1JUD">HAD-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q01399">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q01399">HAD-related</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8702766">8702766</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>113</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.1.1.17"><B>4.1.1.17</B></A></td>
|
||
<td>Ornithine decarboxylase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P24169">P24169</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P24169">DCOS_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ORD">1ORD</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1ORD">PLP-dependent transferase-like and Ornithine decarboxylase C-terminal domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P24169">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P24169">Orn/Lys/Arg decarboxylase, class I</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7563080">7563080</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.1.1.17"><B>4.1.1.17</B></A></td>
|
||
<td>Ornithine decarboxylase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P11926">P11926</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P11926">DCOR_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1D7K">1D7K</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1D7K">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P11926">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P11926">Orn/Lys/Arg decarboxylase, class II</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2587220,2318872">2587220, 2318872</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>114</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.1.1.18"><B>4.1.1.18</B></A></td>
|
||
<td>Lysine decarboxylase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A9H3">P0A9H3</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A9H3">LDCI_ECOLI</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ORD">1ORD</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1ORD">PLP-dependent transferase-like and Ornithine decarboxylase C-terminal domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A9H3">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A9H3">Orn/Lys/Arg decarboxylase class-I</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/4204273">4204273</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.1.1.18"><B>4.1.1.18</B></A></td>
|
||
<td>Lysine decarboxylase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O50657">O50657</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O50657">DCLO_SELRU</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=7ODC">7ODC</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=7ODC">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O50657">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O50657">Orn/Lys/Arg decarboxylase class-II</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11073919">11073919</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>115</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.1.1.19"><B>4.1.1.19</B></A></td>
|
||
<td>Arginine decarboxylase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P28629">P28629</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P28629">ADIA_ECOLI</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1C4K">1C4K</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1C4K">PLP-dependent transferase-like and Ornithine decarboxylase C-terminal domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P28629">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P28629">Orn/Lys/Arg decarboxylase, class I</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/4204273">4204273</A></td>
|
||
<td rowspan=3>At least two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.1.1.19"><B>4.1.1.19</B></A></td>
|
||
<td>Arginine decarboxylase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P21170">P21170</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P21170">SPEA_ECOLI</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1TWI">1TWI</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1TWI">TIM beta/alpha barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P21170">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P21170">Orn/Lys/Arg decarboxylase class II</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8383109,19298070">8383109, 19298070</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.1.1.19"><B>4.1.1.19</B></A></td>
|
||
<td>Arginine decarboxylase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q57764">Q57764</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q57764">PDAD_METJA</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1N2M">1N2M</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1N2M">Pyruvoyl-dependent histidine and arginine decarboxylases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q57764">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q57764">Pyruvoyl-dependent ArgDC</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11980912">11980912</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>116</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.1.1"><B>4.2.1.1</B></A></td>
|
||
<td>Carbonate dehydratase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P17582">P17582</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P17582">CYNT_ECOLI</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1EKJ">1EKJ</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1EKJ">Resolvase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P17582">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P17582">Beta-carbonic anhydrase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1740425">1740425</A></td>
|
||
<td rowspan=3>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.1.1"><B>4.2.1.1</B></A></td>
|
||
<td>Carbonate dehydratase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P00915">P00915</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P00915">CAH1_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2FOY">2FOY</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2FOY">Carbonic anhydrase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P00915">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P00915">Eukaryotic-type carbonic anhydrase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/804171,4207120">804171, 4207120</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.1.1"><B>4.2.1.1</B></A></td>
|
||
<td>Carbonate dehydratase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P40881">P40881</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P40881">CAH_METTE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1QQ0">1QQ0</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QQ0">Single-stranded left-handed beta-helix</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P40881">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P40881">Gamma-carbonic anhydrase-like</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8041719">8041719</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>117</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.1.2"><B>4.2.1.2</B></A></td>
|
||
<td>Fumarate hydratase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P05042">P05042</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P05042">FUMC_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1FUO">1FUO</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1FUO">L-aspartase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P05042">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P05042">L-aspartase/fumarase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8909293,3282546">8909293, 3282546</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.1.2"><B>4.2.1.2</B></A></td>
|
||
<td>Fumarate hydratase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P00923">P00923</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P00923">FUMA_ECOLI</A></td>
|
||
<td>C-term domain is <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2ISB">2ISB</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2ISB">The "swivelling" beta/beta/alpha domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P00923">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P00923">Class I fumarase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1917897">1917897</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>118</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.1.10"><B>4.2.1.10</B></A></td>
|
||
<td>3-dehydroquinate dehydratase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P43877">P43877</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P43877">AROQ_ACTPL</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1UQR">1UQR</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1UQR">Flavodoxin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P43877">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P43877">Type II 3-dehydroquinate dehydratase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/14993670,8170389,2848727">14993670, 8170389, 2848727</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.1.10"><B>4.2.1.10</B></A></td>
|
||
<td>3-dehydroquinate dehydratase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P05194">P05194</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P05194">AROD_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1QFE">1QFE</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QFE">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P05194">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P05194">Class I aldolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3541912">3541912</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>119</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.1.17"><B>4.2.1.17</B></A></td>
|
||
<td>Enoyl-CoA hydratase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P21177">P21177</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P21177">FADB_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1WDK">1WDK</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1WDK">ClpP/crotonase, Rossmann-fold and Thiolase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P21177">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P21177">Enoyl-CoA hydratase/isomerase family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3286611">3286611</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.1.17"><B>4.2.1.17</B></A></td>
|
||
<td>Enoyl-CoA hydratase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P96807">P96807</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P96807">ECH1_MYCTU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2C2I">2C2I</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2C2I">Thioesterase/thiol ester dehydrase-isomerase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P96807">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P96807">MaoC dehydratase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16963641">16963641</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>120</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.1.78"><B>4.2.1.78</B></A></td>
|
||
<td>Norcoclaurine synthase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/A2A1A0">A2A1A0</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/A2A1A0">NCS1_COPJA</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1GP4">1GP4</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1GP4">Double-stranded beta-helix</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=A2A1A0">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/A2A1A0">2OG-Fe(II) oxygenase superfamily</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/17204481">17204481</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.1.78"><B>4.2.1.78</B></A></td>
|
||
<td>Norcoclaurine synthase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q67A25">Q67A25</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q67A25">NCS_THLFG</A>, <A href="http://www.uniprot.org/uniprot/A2A1A1">NCS2_COPJA</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2VNE">2VNE</A>, similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1FM4">1FM4</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1FM4">TBP-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q67A25">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q67A25">Pathogenesis-related protein</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/17696451,18391427">17696451, 18391427</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>121</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.1.92"><B>4.2.1.92</B></A></td>
|
||
<td>Hydroperoxide dehydratase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q96242">Q96242</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q96242">CP74A_ARATH</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2RCH">2RCH</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1BU7">Cytochrome P450</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q96242">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q96242">Cytochrome P450</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8756596,10420644">8756596, 10420644</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.1.92"><B>4.2.1.92</B></A></td>
|
||
<td>Hydroperoxide dehydratase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O16025">O16025</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O16025">AOSL_PLEHO</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1U5U">1U5U</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1U5U">Heme-dependent catalase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O16025">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O16025">Lipoxygenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10559269,9302294">10559269, 9302294</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>122</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.2.2"><B>4.2.2.2</B></A></td>
|
||
<td>Pectate lyase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0C1C2">P0C1C2</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0C1C2">PEL3_ERWCA</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1PLU">1PLU</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1PLU">Single-stranded right-handed beta-helix</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0C1C2">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0C1C2">Pectate lyase C</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12226275">12226275</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.2.2"><B>4.2.2.2</B></A></td>
|
||
<td>Pectate lyase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P14005">P14005</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P14005">PELP_PECCC</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1NXC">1NXC</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1NXC">Alpha/alpha toroid</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P14005">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P14005">Periplasmic pectate lyase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2695748,17881361">2695748, 17881361</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=4>123</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.99.18"><B>4.2.99.18</B></A></td>
|
||
<td>DNA-(apurinic or apyrimidinic site) lyase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P20625">P20625</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P20625">END3_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2ABK">2ABK</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2ABK">DNA-glycosylase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P20625">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P20625">Endonuclease III</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2669955">2669955</A></td>
|
||
<td rowspan=4>Four distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.99.18"><B>4.2.99.18</B></A></td>
|
||
<td>DNA-(apurinic or apyrimidinic site) lyase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P27695">P27695</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P27695">APEX1_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1E9N">1E9N</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1E9N">DNase I-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P27695">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P27695">DNase I-like</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1383925,1380694">1383925, 1380694</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.99.18"><B>4.2.99.18</B></A></td>
|
||
<td>DNA-(apurinic or apyrimidinic site) lyase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P22936">P22936</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P22936">APN1_YEAST</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1QTW">1QTW</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QTW">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P22936">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P22936">Endonuclease IV</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3056935">3056935</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.99.18"><B>4.2.99.18</B></A></td>
|
||
<td>DNA-(apurinic or apyrimidinic site) lyase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P05523">P05523</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P05523">FPG_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1K82">1K82</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1K82">MutM-like DNA repair protein</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P05523">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P05523">Middle domain of MutM-like DNA repair proteins</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11106507,14607836,11912217">11106507, 14607836, 11912217</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>124</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.3.1.17"><B>4.3.1.17</B></A></td>
|
||
<td>L-serine ammonia-lyase (was 4.2.1.13)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P16095">P16095</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P16095">SDHL_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2IQQ">2IQQ</A> (N-term)</td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2IQQ">FwdE/GAPDH domain-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P16095">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P16095">Fe-S dependent L-serine dehydratase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2504697,8436113,8385012">2504697, 8436113, 8385012</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.3.1.17"><B>4.3.1.17</B></A></td>
|
||
<td>L-serine ammonia-lyase (was 4.2.1.13)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P20132">P20132</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P20132">SDHL_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1P5J">1P5J</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1P5J">Tryptophan synthase beta subunit-like PLP-dependent enzymes</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P20132">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P20132">Serine/threonine dehydratase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/14596599,14646100,2674117">14596599, 14646100, 2674117</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=4>125</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.6.1.1"><B>4.6.1.1</B></A></td>
|
||
<td>Adenylate cyclase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q08828">Q08828</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q08828">CYA1_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1CS4">1CS4</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1CS4">P-loop containing NTPases and Ferredoxin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q08828">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q08828">Adenylate/guanylate cyclase (class III AC)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8314585">8314585</A></td>
|
||
<td rowspan=4>At least three distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.6.1.1"><B>4.6.1.1</B></A></td>
|
||
<td>Adenylate cyclase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O69199">O69199</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O69199">O69199_AERHY</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2ACA">2ACA</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2ACA">CYTH-like phosphatases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O69199">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O69199">CYTH domain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9642185,16905149">9642185, 16905149</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.6.1.1"><B>4.6.1.1</B></A></td>
|
||
<td>Adenylate cyclase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P15318">P15318</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P15318">CYAA_BORPE</A></td>
|
||
<td>N-term is <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1YRU">1YRU</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1YRU">EF Hand-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P15318">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P15318">Anthrax toxin LF (class II AC)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2897067,16138079">2897067, 16138079</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.6.1.1"><B>4.6.1.1</B></A></td>
|
||
<td>Adenylate cyclase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P00936">P00936</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P00936">CYAA_ECOLI</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P00936">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P00936">Adenylate_cyclase class I</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/6344011,92011391">6344011, 92011391</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>126</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.1.1.1"><B>5.1.1.1</B></A></td>
|
||
<td>Alanine racemase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A6B4">P0A6B4</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A6B4">ALR1_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2RJG">2RJG</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1RCQ">Domain of alpha and beta subunits of F1 ATP synthase-like and TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A6B4">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A6B4">Alanine racemase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/18434499">18434499</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.1.1.1"><B>5.1.1.1</B></A></td>
|
||
<td>Alanine racemase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9UW18">Q9UW18</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9UW18">TOXG_COCCA</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1M6S">1M6S</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1M6S">PLP-dependent transferase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9UW18">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9UW18">Beta-eliminating lyase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10671527">10671527</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>127</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.1.1.13"><B>5.1.1.13</B></A></td>
|
||
<td>Aspartate racemase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P83989">P83989</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q2L695">Q2L695_ANABR</A> (RACD_ANABR)</td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1WTC">1WTC</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1WTC">Tryptophan synthase beta subunit-like PLP-dependent enzymes</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P83989">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P83989">Pyridoxal-phosphate dependent enzyme</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12568809,16452311">12568809, 16452311</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.1.1.13"><B>5.1.1.13</B></A></td>
|
||
<td>Aspartate racemase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O58403">O58403</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O58403">O58403_PYRHO</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1JFL">1JFL</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1JFL">ATC-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O58403">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O58403">Asp/Glu/Hydantoin racemase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12051922">12051922</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>128</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.2.1.8"><B>5.2.1.8</B></A></td>
|
||
<td>Peptidylprolyl isomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0AFL3">P0AFL3</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0AFL3">PPIA_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1CLH">1CLH</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1CLH">Cyclophilin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0AFL3">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0AFL3">Cyclophilin</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9501079,17909185">9501079, 17909185</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.2.1.8"><B>5.2.1.8</B></A></td>
|
||
<td>Peptidylprolyl isomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P45523">P45523</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P45523">FKBA_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1Q6H">1Q6H</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1Q6H">FKBP-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P45523">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P45523">FKBP-type PPIase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1379319">1379319</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>129</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.3.1.6"><B>5.3.1.6</B></A></td>
|
||
<td>Ribose-5-phosphate isomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A7Z0">P0A7Z0</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A7Z0">RPIA_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1LKZ">1LKZ</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1LKZ">NagB/RpiA/CoA transferase-like and Ferredoxin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A7Z0">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A7Z0">Ribose 5-phosphate isomerase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12211039,8366047">12211039, 8366047</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.3.1.6"><B>5.3.1.6</B></A></td>
|
||
<td>Ribose-5-phosphate isomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P37351">P37351</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P37351">RPIB_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1NN4">1NN4</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1NN4">Ribose/Galactose isomerase RpiB/AlsB</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P37351">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P37351">Ribose/Galactose Isomerase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/14499611,8576032">14499611, 8576032</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>130</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.3.1.8"><B>5.3.1.8</B></A></td>
|
||
<td>Mannose-6-phosphate isomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q59935">Q59935</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q59935">MANA_STRMU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1QWR">1QWR</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QWR">Double-stranded beta-helix</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q59935">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q59935">RmlC-like cupins</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8293960">8293960</A></td>
|
||
<td rowspan=3>At least two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.3.1.8"><B>5.3.1.8</B></A></td>
|
||
<td>Mannose-6-phosphate isomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q4JCA7">Q4JCA7</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q4JCA7">PGMI_SULAC</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1TZB">1TZB</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1TZB">SIS domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q4JCA7">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q4JCA7">SIS_domain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/14551194">14551194</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.3.1.8"><B>5.3.1.8</B></A></td>
|
||
<td>Mannose-6-phosphate isomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P29954">P29954</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P29954">MANA_RHIME</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2GZ6">2GZ6</A></td>
|
||
<td>Predicted: Alpha/alpha toroid</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P29954">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P29954">GlcNAc 2-epimerase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1452036">1452036</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>131</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.3.1.9"><B>5.3.1.9</B></A></td>
|
||
<td>Glucose-6-phosphate isomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P06744">P06744</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P06744">G6PI_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1JLH">1JLH</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1JLH">SIS domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P06744">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P06744">Phosphoglucose isomerase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12573240">12573240</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.3.1.9"><B>5.3.1.9</B></A></td>
|
||
<td>Glucose-6-phosphate isomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P84140">P84140</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P84140">G6PI_THELI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1J3P">1J3P</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1J3P">Double-stranded beta-helix</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P84140">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P84140">Glucose-6-phosphate isomerase (GPI) (Archaeal-type GPI)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12560104">12560104</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>132</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.3.3.2"><B>5.3.3.2</B></A></td>
|
||
<td>Isopentenyl-diphosphate delta-isomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P50740">P50740</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P50740">IDI2_BACSU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1P0K">1P0K</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1P0N">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P50740">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P50740">FMN-dependent dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15206931,12798687">15206931, 12798687</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.3.3.2"><B>5.3.3.2</B></A></td>
|
||
<td>Isopentenyl-diphosphate delta-isomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q46822">Q46822</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q46822">IDI_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1HZT">1HZT</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1HZT">NUDIX</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q46822">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q46822">NUDIX</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10419945,11285217">10419945, 11285217</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>133</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.3.3.10"><B>5.3.3.10</B></A></td>
|
||
<td>5-carboxymethyl-2-hydroxymuconate delta-isomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q05354">Q05354</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q05354">HPCD_ECOLX</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1OTG">1OTG</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1OTG">Tautomerase/MIF</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q05354">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q05354">CHMI, 5-carboxymethyl-2-hydroxymuconate isomerase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8547259,2194841">8547259, 2194841</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.3.3.10"><B>5.3.3.10</B></A></td>
|
||
<td>5-carboxymethyl-2-hydroxymuconate delta-isomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P37352">P37352</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P37352">HPCE_ECOLX</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1I7O">1I7O</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1gtt">FAH</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P37352">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P37352">Fumarylacetoacetate (FAA) hydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8223600">8223600</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>134</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.3.99.2"><B>5.3.99.2</B></A></td>
|
||
<td>Prostaglandin-D synthase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O60760">O60760</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O60760">PTGD2_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1IYH">1IYH</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1IYH">Thioredoxin fold and GST C-terminal domain-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O60760">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O60760">Glutathione S-transferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9353279,10824118">9353279, 10824118</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.3.99.2"><B>5.3.99.2</B></A></td>
|
||
<td>Prostaglandin-D synthase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P41222">P41222</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P41222">PTGDS_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2CZT">2CZT</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1X71">Lipocalins</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P41222">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P41222">Lipocalin family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8336134,9475419">8336134, 9475419</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>135</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.3.99.3"><B>5.3.99.3</B></A></td>
|
||
<td>Prostaglandin-E synthase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9N0A4">Q9N0A4</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9N0A4">PGES2_MACFA</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1Z9H">1Z9H</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1Z9H">Thioredoxin fold and GST C-terminal domain-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9N0A4">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9N0A4">Glutathione S-transferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15854652,11866447">15854652, 11866447</A></td>
|
||
<td rowspan=3>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.3.99.3"><B>5.3.99.3</B></A></td>
|
||
<td>Prostaglandin-E synthase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O14684">O14684</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O14684">PTGES_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2H8A">2H8A</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2H8A">MAPEG domain-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O14684">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O14684">MAPEG family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12672824,12460774">12672824, 12460774</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.3.99.3"><B>5.3.99.3</B></A></td>
|
||
<td>Prostaglandin-E synthase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q15185">Q15185</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q15185">TEBP_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1EJF">1EJF</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1EJF">HSP20-like chaperones</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q15185">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q15185">CS domain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10922363,10811660">10922363, 10811660</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>136</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.4.2.1"><B>5.4.2.1</B></A></td>
|
||
<td>Phosphoglycerate mutase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P31217">P31217</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P31217">GPMA_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1E59">1E59</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1E59">Phosphoglycerate mutase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P31217">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P31217">Phosphoglycerate mutase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11038361">11038361</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.4.2.1"><B>5.4.2.1</B></A></td>
|
||
<td>Phosphoglycerate mutase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P52832">P52832</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P52832">GPMI_PSESM</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1EJJ">1EJJ</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1EJJ">Alkaline phosphatase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P52832">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P52832">2,3-Bisphosphoglycerate-independent phosphoglycerate mutase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12076796">12076796</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>137</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.4.2.8"><B>5.4.2.8</B></A></td>
|
||
<td>Phosphomannomutase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P26405">P26405</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P26405">RFBK_SALTY</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1K2Y">1K2Y</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1K2Y">Phosphoglucomutase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P26405">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P26405">Phosphoglucomutase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1710759">1710759</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.4.2.8"><B>5.4.2.8</B></A></td>
|
||
<td>Phosphomannomutase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q92871">Q92871</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q92871">PMM1_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2FUC">2FUC</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2FUC">HAD-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q92871">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q92871">Eukaryotic phosphomannomutase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9119384">9119384</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>138</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.4.99.5"><B>5.4.99.5</B></A></td>
|
||
<td>Chorismate mutase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P42517">P42517</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P42517">CHMU_ENTAG</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2AO2">2AO2</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2AO2">Chorismate mutase II</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P42517">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P42517">Secreted chorismate mutase-like</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8335631,9497350,7496534">8335631, 9497350, 7496534</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.4.99.5"><B>5.4.99.5</B></A></td>
|
||
<td>Chorismate mutase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P19080">P19080</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P19080">CHMU_BACSU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1COM">1COM</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1COM">Bacillus chorismate mutase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P19080">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P19080">Chorismate mutase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8378335">8378335</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>139</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.5.1.1"><B>5.5.1.1</B></A></td>
|
||
<td>Muconate cycloisomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P08310">P08310</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P08310">CATB_PSEPU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1MUC">1MUC</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1MUC">TIM beta/alpha-barrel and Enolase N-terminal domain-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P08310">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P08310">D-glucarate dehydratase-like</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3609743,3612800">3609743, 3612800</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.5.1.1"><B>5.5.1.1</B></A></td>
|
||
<td>Muconate cycloisomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P46057">P46057</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P46057">MLE_TRICU</A></td>
|
||
<td>C-term is similar to C-term of <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1JOF">1JOF</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1JOF">7-bladed beta-propeller</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P46057">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P46057">WD40/YVTN repeat</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8110801,11937053">8110801, 11937053</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>140</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.99.1.2"><B>5.99.1.2</B></A></td>
|
||
<td>DNA topoisomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P06612">P06612</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P06612">TOP1_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1CY1">1CY1</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1CY1">Prokaryotic type I DNA topoisomerase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P06612">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P06612">Prokaryotic type I DNA topoisomerase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3029379,8114910,7779808">3029379, 8114910, 7779808</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.99.1.2"><B>5.99.1.2</B></A></td>
|
||
<td>DNA topoisomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P11387">P11387</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P11387">TOP1_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1LPQ">1LPQ</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1LPQ">DNA breaking-rejoining enzymes</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P11387">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P11387">Eukaryotic DNA topoisomerase I</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/98155246,8747458,16352556">98155246, 8747458, 16352556</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>141</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/6.1.1.6"><B>6.1.1.6</B></A></td>
|
||
<td>Lysine<EFBFBD>tRNA ligase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P13030">P13030</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P13030">SYK1_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1BBU">1BBU</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1BBU">Class II aaRS and biotin synthetases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P13030">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P13030">Class II aminoacyl-tRNA synthetase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7735833,11887185,2183178">7735833, 11887185, 2183178</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/6.1.1.6"><B>6.1.1.6</B></A></td>
|
||
<td>Lysine<EFBFBD>tRNA ligase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9YFT9">Q9YFT9</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9YFT9">SYK_AERPE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1IRX">1IRX</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1IRX">Adenine nucleotide alpha hydrolase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9YFT9">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9YFT9">Class I lysyl-tRNA synthetase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9353192,11887185,16529662">9353192, 11887185, 16529662</A></td>
|
||
</TR>
|
||
|
||
<TR bgColor=#99cc66>
|
||
<TD vAlign=top width="5%"><FONT size=+1><B>No.</B></FONT></TD>
|
||
<TD vAlign=top width="5%"><FONT size=+1><B>EC no.</B></CENTER></FONT></TD>
|
||
<TD vAlign=top width="15%"><FONT size=+1><B>Enzyme name</B></FONT></TD>
|
||
<TD vAlign=top width="5%"><FONT size=+1><B>NCBI</B></FONT></TD>
|
||
<TD vAlign=top width="5%"><FONT size=+1><B>UniProt</B></FONT></FONT></TD>
|
||
<TD vAlign=top width="5%"><FONT size=+1><B>PDB</B></FONT></TD>
|
||
<TD vAlign=top width="15%"><FONT size=+1><B>SCOP fold</B></FONT></TD>
|
||
<TD vAlign=top width="5%"><FONT size=+1><B>Super-family</B></FONT></TD>
|
||
<TD vAlign=top width="15%"><FONT size=+1><B>Family (Pfam)</B></FONT></TD>
|
||
<TD vAlign=top width="10%"><FONT size=+1><B>Ref.</B></FONT></TD>
|
||
<TD vAlign=top width="15%"><FONT size=+1><B>Predicted</B></FONT></TD>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>142</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.2.1.31"><B>1.2.1.31</B></A></td>
|
||
<td>L-aminoadipate-semialdehyde dehydrogenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P49419">P49419</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P49419">AL7A1_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2J6L">2J6L</A>, similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1EUH">1EUH</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1BI9">ALDH-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P49419">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P49419">Aldehyde dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16491085,18694748">16491085, 18694748</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.2.1.31"><B>1.2.1.31</B></A></td>
|
||
<td>L-aminoadipate-semialdehyde dehydrogenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P07702">P07702</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P07702">LYS2_YEAST</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2VSQ">2VSQ</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1L5A">CoA-dependent acyltransferases</A>, <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1MDB">Acetyl-CoA synthetase-like</A> and <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1UDB">Rossmann-fold</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P07702">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P07702">NAD_binding_4</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10320345,12756539">10320345, 12756539</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>143</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.3.1.9"><B>1.3.1.9</B></A></td>
|
||
<td>Enoyl-[acyl-carrier-protein] reductase (NADH)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A5Y6">P0A5Y6</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A5Y6">INHA_MYCTU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2NV6">2NV6</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2NV6">Rossmann-fold</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A5Y6">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A5Y6">Short-chain dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10336454">10336454</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.3.1.9"><B>1.3.1.9</B></A></td>
|
||
<td>Enoyl-[acyl-carrier-protein] reductase (NADH)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P07149">P07149</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P07149">FAS1_YEAST</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3HMJ">3HMJ</A></td>
|
||
<td>Predicted: TIM beta/alpha-barrel</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P07149">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P07149">Enoyl-[acyl-carrier-protein] reductase (Fungal fatty acid synthetase subunit beta)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/17431175,19679086">17431175, 19679086</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>144</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.3.1.20"><B>1.3.1.20</B></A></td>
|
||
<td>Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q7JK39">Q7JK39</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q7JK39">DHDH_MACFU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2O48">2O48</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1RYD">Rossmann-fold and FwdE/GAPDH domain-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q7JK39">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q7JK39">Oxidoreductase family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11306093,10477285,17654552">11306093, 10477285, 17654552</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.3.1.20"><B>1.3.1.20</B></A></td>
|
||
<td>Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q04828">Q04828</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q04828">AK1C1_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1MRQ">1MRQ</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1MRQ">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q04828">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q04828">Aldo/keto reductase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11013348,8573067">11013348, 8573067</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>145</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.5.1.3"><B>1.5.1.3</B></A></td>
|
||
<td>Dihydrofolate reductase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P11045">P11045</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P11045">DYR_BACSU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1MVS">1MVS</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1MVS">Dihydrofolate reductase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P11045">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P11045">Dihydrofolate reductases</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1731871">1731871</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.5.1.3"><B>1.5.1.3</B></A></td>
|
||
<td>Dihydrofolate reductase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0AFS3">P0AFS3</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0AFS3">FOLM_ECOLI</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3edm">3edm</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2D1Y">Rossmann-fold</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0AFS3">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0AFS3">Short chain dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/14617668">14617668</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>146</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.14.13.39"><B>1.14.13.39</B></A></td>
|
||
<td>Nitric-oxide synthase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P29476">P29476</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P29476">NOS1_RAT</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1TLL">1TLL</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1TLL">Reductase/isomerase/elongation factor common domain and Flavodoxin-like and Ferredoxin reductase-like C-terminal NADP-linked domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P29476">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P29476">NOS family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1379068">1379068</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.14.13.39"><B>1.14.13.39</B></A></td>
|
||
<td>Nitric-oxide synthase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q66GP9">Q66GP9</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q66GP9">NOS1_ARATH</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3EC1">3EC1</A></td>
|
||
<td>Predicted: P-loop</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q66GP9">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q66GP9">Plant NOS family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/14526079,11916378">14526079, 11916378</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>147</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.1.1.17"><B>2.1.1.17</B></A></td>
|
||
<td>Phosphatidylethanolamine N-methyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q05197">Q05197</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q05197">PMTA_RHOSH</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3DH0">3DH0</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1XXL">SAM-dependent methyltransferases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q05197">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q05197">SAM-dependent methyltransferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8340421">8340421</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.1.1.17"><B>2.1.1.17</B></A></td>
|
||
<td>Phosphatidylethanolamine N-methyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P05374">P05374</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P05374">PEM1_YEAST</A></td>
|
||
<td>-</td>
|
||
<td>Integral membrane protein</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P05374">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P05374">Pfam hit</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2445736">2445736</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>148</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.1.1.31"><B>2.1.1.31</B></A></td>
|
||
<td>tRNA (guanine-N1-)-methyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A873">P0A873</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A873">TRMD_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1P9P">1P9P</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1P9P">Alpha/beta knot</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A873">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A873">TRNA (Guanine-1)-methyltransferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/6337136,14583191">6337136, 14583191</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.1.1.31"><B>2.1.1.31</B></A></td>
|
||
<td>tRNA (guanine-N1-)-methyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q32P41">Q32P41</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q32P41">TRMT5_HUMAN</A></td>
|
||
<td>C-term is similar to N-term of <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2FRN">2FRN</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2FRN">S-adenosyl-L-methionine-dependent methyltransferases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q32P41">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q32P41">Met-10+ like-protein</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15248782">15248782</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>149</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.1.1"><B>2.3.1.1</B></A></td>
|
||
<td>Amino-acid N-acetyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A6C5">P0A6C5</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A6C5">ARGA_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2R8V">2R8V</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1YK3">Acyl-CoA N-acyltransferases (Nat)</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A6C5">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A6C5">Acetyltransferase (GNAT) family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16890">16890</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.1.1"><B>2.3.1.1</B></A></td>
|
||
<td>Amino-acid N-acetyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q04728">Q04728</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q04728">ARGJ_YEAST</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1VZ6">1VZ6</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1VZ6">DmpA/ArgJ-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q04728">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q04728">ArgJ family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9428669">9428669</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>150</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.1.43"><B>2.3.1.43</B></A></td>
|
||
<td>Phosphatidylcholine<EFBFBD>sterol O-acyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P04180">P04180</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P04180">LCAT_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ex9">1ex9</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1EX9">Alpha/beta hydrolase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P04180">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P04180">Lecithin:cholesterol acyltransferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2823898">2823898</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.1.43"><B>2.3.1.43</B></A></td>
|
||
<td>Phosphatidylcholine<EFBFBD>sterol O-acyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P10480">P10480</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P10480">GCAT_AERHY</A></td>
|
||
<td>similar to: <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1PP4">1PP4</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1PP4">Flavodoxin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P10480">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P10480">Lipase_GDSL</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3280033">3280033</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>151</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.1.51"><B>2.3.1.51</B></A></td>
|
||
<td>1-acylglycerol-3-phosphate O-acyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O15120">O15120</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O15120">PLCB_HUMAN</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1K30">1K30</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1K30">Glycerol-3-phosphate (1)-acyltransferase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O15120">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O15120">Acyltransferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9242711">9242711</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.1.51"><B>2.3.1.51</B></A></td>
|
||
<td>1-acylglycerol-3-phosphate O-acyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q12385">Q12385</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q12385">ICT1_YEAST</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1IUN">1IUN</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1IUN">Alpha/beta hydrolase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q12385">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q12385">Alpha/beta hydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/18252723">18252723</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>152</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.1.84"><B>2.3.1.84</B></A></td>
|
||
<td>Alcohol O-acetyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P40353">P40353</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P40353">ATF1_YEAST</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1L5A">1L5A</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1L5A">CoA-dependent acyltransferases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P40353">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P40353">Alcohol acetyltransferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8085822,7764365">8085822, 7764365</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.1.84"><B>2.3.1.84</B></A></td>
|
||
<td>Alcohol O-acetyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P38295">P38295</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P38295">MCFS2_YEAST</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1VA4">1VA4</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1VA4">Alpha/beta hydrolase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P38295">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P38295">Abhydrolase_1</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16361250">16361250</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>153</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.4.21"><B>2.7.4.21</B></A></td>
|
||
<td>Inositol-hexakisphosphate kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q12494">Q12494</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q12494">KCS1_YEAST</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1W2D">1W2D</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1W2D">SAICAR synthase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q12494">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q12494">Inositol phosphokinase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15350214">15350214</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.4.21"><B>2.7.4.21</B></A></td>
|
||
<td>Inositol-hexakisphosphate kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q06685">Q06685</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q06685">VIP1_YEAST</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1GSA">1GSA</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1GSA">ATP-grasp</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q06685">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q06685">Histidine acid phosphatase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/17412958,17690096">17412958, 17690096</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>154</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.1"><B>3.1.1.1</B></A></td>
|
||
<td>Carboxylesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O33407">O33407</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O33407">ESTA_PSEAE</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1PP4">1PP4</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1PP4">Flavodoxin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O33407">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O33407">GDSL-like Lipase/Acylhydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10559163">10559163</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.1"><B>3.1.1.1</B></A></td>
|
||
<td>Carboxylesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P13001">P13001</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P13001">BIOH_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1M33">1M33</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1M33">Alpha/beta hydrolase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P13001">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P13001">Alpha/beta hydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12732651">12732651</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>155</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.47"><B>3.1.1.47</B></A></td>
|
||
<td>1-alkyl-2-acetylglycerophosphocholine esterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q13093">Q13093</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q13093">PAFA_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3D59">3D59</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1JFR">Alpha/beta hydrolase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q13093">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q13093">Serine esterase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8624782,18784071">8624782, 18784071</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.47"><B>3.1.1.47</B></A></td>
|
||
<td>1-alkyl-2-acetylglycerophosphocholine esterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P68401">P68401</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P68401">PA1B2_BOVIN</A> (beta) and <A href="http://www.uniprot.org/uniprot/Q29460">PA1B3_BOVIN</A> (gamma)</td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1FXW">1FXW</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1FXW">Flavodoxin-like (beta and gamma)</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P68401">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P68401">GDSL' lipolytic enzyme</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8083218,8985254">8083218, 8985254</A></td>
|
||
<td>Predicted analogs (cytosolic ezyme is formed of three subunits)</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>156</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.2.2"><B>3.1.2.2</B></A></td>
|
||
<td>Palmitoyl-CoA hydrolase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O55137">O55137</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O55137">ACOT1_MOUSE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3HLK">3HLK</A></td>
|
||
<td>Predicted: Alpha/beta hydrolase</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O55137">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O55137">BAAT / Acyl-CoA thioester hydrolase C terminal</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10567408">10567408</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.2.2"><B>3.1.2.2</B></A></td>
|
||
<td>Palmitoyl-CoA hydrolase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O00154">O00154</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O00154">BACH_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1YLI">1YLI</A>, <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=4HBT">4HBT</A>?</td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1YLI">Thioesterase/thiol ester dehydrase-isomerase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O00154">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O00154">Thioesterase superfamily</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10578051">10578051</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>157</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.2.14"><B>3.1.2.14</B></A></td>
|
||
<td>Oleoyl-[acyl-carrier-protein] hydrolase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P08635">P08635</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P08635">SAST_RAT</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1C4X">1C4X</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1C4X">Alpha/beta hydrolase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P08635">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P08635">Thioesterase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3105579">3105579</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.2.14"><B>3.1.2.14</B></A></td>
|
||
<td>Oleoyl-[acyl-carrier-protein] hydrolase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P07149">P07149</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P07149">FAS1_YEAST</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1S9C">1S9C</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1S9C">Thioesterase/thiol ester dehydrase-isomerase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P07149">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P07149">Acyl transferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3528750,3031066">3528750, 3031066</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>158</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.1"><B>3.1.3.1</B></A></td>
|
||
<td>Alkaline phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P00634">P00634</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P00634">PPB_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ED8">1ED8</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1ED8">Alkaline phosphatase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P00634">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P00634">Alkaline phosphatase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2010919">2010919</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.1"><B>3.1.3.1</B></A></td>
|
||
<td>Alkaline phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q05205">Q05205</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q05205">PPB_LYSEN</A></td>
|
||
<td>similar to C-term of <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1XZW">1XZW</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1XZW">Metallo-dependent phosphatases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q05205">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q05205">Calcineurin-like phosphoesterase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1856159">1856159</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>159</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.3"><B>3.1.3.3</B></A></td>
|
||
<td>Phosphoserine phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9UBQ0">Q9UBQ0</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9UBQ0">VPS29_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1W24">1W24</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1W24">Metallo-dependent phosphatases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9UBQ0">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9UBQ0">Calcineurin-like phosphoesterase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16737443">16737443</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.3"><B>3.1.3.3</B></A></td>
|
||
<td>Phosphoserine phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O07014">O07014</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O07014">RSBP_BACSU</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1TXO">1TXO</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1TXO">PP2C-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O07014">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O07014">Protein phosphatase 2C</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10632888">10632888</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR bgColor=#ffff00>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.3"><I>3.1.3.3</I></A></td>
|
||
<td>Phosphoserine phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O82796">O82796</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O82796">SERB_ARATH</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1NNL">1NNL</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1NNL">HAD-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O82796">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O82796">SerB family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10196182">10196182</A></td>
|
||
<td>Hydrolyzes free Ser~P</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>160</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.7"><B>3.1.3.7</B></A></td>
|
||
<td>3'(2'),5'-bisphosphate nucleotidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q42546">Q42546</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q42546">DPNP1_ARATH</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1QGX">1QGX</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QGX">Carbohydrate phosphatase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q42546">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q42546">Inositol monophosphatase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/17993620,10205895">17993620, 10205895</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.7"><B>3.1.3.7</B></A></td>
|
||
<td>3'(2'),5'-bisphosphate nucleotidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O34600">O34600</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O34600">NRNA_BACSU</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1K20">1K20</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1K20">DHH phosphoesterases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O34600">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O34600">DHH</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/17586819">17586819</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>161</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.27"><B>3.1.3.27</B></A></td>
|
||
<td>Phosphatidylglycerophosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P18200">P18200</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P18200">PGPA_ECOLI</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1RFZ">1RFZ</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1RFZ">YutG-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P18200">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P18200">Phosphatidyl-glycerophosphatase A</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/6296050">6296050</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.27"><B>3.1.3.27</B></A></td>
|
||
<td>Phosphatidylglycerophosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A924">P0A924</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A924">PGPB_ECOLI</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1D2T">1D2T</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1D2T">Acid phosphatase/Vanadium-dependent haloperoxidase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A924">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A924">Phosphatidic acid phosphatase (PAP2)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/6296050">6296050</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>162</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.4.3"><B>3.1.4.3</B></A></td>
|
||
<td>Phospholipase C</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P15713">P15713</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P15713">PHLN_PSEAE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2D1G">2D1G</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1N2L">Alkaline phosphatase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P15713">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P15713">Phosphoesterase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2120196">2120196</A></td>
|
||
<td>Predicted analogs, by VAST</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.4.3"><B>3.1.4.3</B></A></td>
|
||
<td>Phospholipase C</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q0TV31">Q0TV31</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q0TV31">PHLC_CLOP1</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1QM6">1QM6</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QM6">Phospholipase C/P1 nuclease</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q0TV31">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q0TV31">Zinc dependent phospholipase C</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11008117,12009886">11008117, 12009886</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>163</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.4.4"><B>3.1.4.4</B></A></td>
|
||
<td>Phospholipase D</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P20626">P20626</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P20626">PLD_CORPS</A></td>
|
||
<td>-</td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1FIY">TIM beta/alpha-barrel (only motif)</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P20626">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P20626">Pfam hit</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2407718,7934899">2407718, 7934899</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.4.4"><B>3.1.4.4</B></A></td>
|
||
<td>Phospholipase D</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q53728">Q53728</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q53728">PLD_STRAT</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1F0I">1F0I</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1F0I">Phospholipase D/nuclease</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q53728">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q53728">Phospholipase D Active site motif</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7765769,10089437,18338352">7765769, 10089437, 18338352</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=4>164</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.4.12"><B>3.1.4.12</B></A></td>
|
||
<td>Sphingomyelin phosphodiesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P17405">P17405</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P17405">ASM_HUMAN</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2AHD">2AHD</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2AHD">Metallo-dependent phosphatases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P17405">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P17405">Calcineurin-like phosphoesterase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1840600,12631268">1840600, 12631268</A></td>
|
||
<td>Predicted analogs (acid)</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.4.12"><B>3.1.4.12</B></A></td>
|
||
<td>Sphingomyelin phosphodiesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q6UWV6">Q6UWV6</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q6UWV6">ENPP7_HUMAN</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2GS0">2GS0</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2GS0">PH domain-like barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q6UWV6">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q6UWV6">Type I phosphodiesterase / nucleotide pyrophosphatase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12885774">12885774</A></td>
|
||
<td>Predicted analogs (alkaline)</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.4.12"><B>3.1.4.12</B></A></td>
|
||
<td>Sphingomyelin phosphodiesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O60906">O60906</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O60906">NSMA_HUMAN</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1I9Y">1I9Y</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1I9Y">DNase I-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O60906">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O60906">Endonuclease/Exonuclease/phosphatase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10608884">10608884</A></td>
|
||
<td>Predicted analogs (neutral)</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.4.12"><B>3.1.4.12</B></A></td>
|
||
<td>Sphingomyelin phosphodiesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9NXE4">Q9NXE4</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9NXE4">NSMA3_HUMAN</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9NXE4">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9NXE4">Pfam hit</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16517606">16517606</A></td>
|
||
<td>Predicted analogs (neutral)</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>165</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.4.16"><B>3.1.4.16</B></A></td>
|
||
<td>2',3'-cyclic-nucleotide 2'-phosphodiesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q2FZ08">Q2FZ08</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q2FZ08">CNPD_STAA8</A></td>
|
||
<td>-</td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1F0J">HD-domain/PDEase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q2FZ08">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q2FZ08">2',3' cyclic nucleotide phosphodiesterase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/17951247,15853881">17951247, 15853881</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.4.16"><B>3.1.4.16</B></A></td>
|
||
<td>2',3'-cyclic-nucleotide 2'-phosphodiesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P08331">P08331</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P08331">CN16_ECOLI</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2USH">2USH</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2USH">5-nucleotidase and Metallo-dependent_phosphatases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P08331">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P08331">5'-nucleotidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3005231">3005231</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>166</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.4.17"><B>3.1.4.17</B></A></td>
|
||
<td>3',5'-cyclic-nucleotide phosphodiesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q07343">Q07343</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q07343">PDE4B_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1XLX">1XLX</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1XLX">HD-domain/PDEase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q07343">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q07343">Cyclic nucleotide phosphodiesterase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9371714,8384210">9371714, 8384210</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.4.17"><B>3.1.4.17</B></A></td>
|
||
<td>3',5'-cyclic-nucleotide phosphodiesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P22434">P22434</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P22434">PDE1_YEAST</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1P9E">1P9E</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1P9E">Metallo-hydrolase/oxidoreductase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P22434">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P22434">cAMP phosphodiesterase class-II</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2824992">2824992</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>167</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.4.35"><B>3.1.4.35</B></A></td>
|
||
<td>3',5'-cyclic-GMP phosphodiesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/B0G0Y8">B0G0Y8</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/B0G0Y8">PDE3_DICDI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2HD1">2HD1</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2HD1">HD-domain/PDEase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=B0G0Y8">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/B0G0Y8">3'5'-cyclic nucleotide phosphodiesterase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11171061,17040207">11171061, 17040207</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.4.35"><B>3.1.4.35</B></A></td>
|
||
<td>3',5'-cyclic-GMP phosphodiesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P12019">P12019</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P12019">PDE1_DICDI</A></td>
|
||
<td>similar to: <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1KO2">1KO2</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1KO2">Metallo-hydrolase/oxidoreductase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P12019">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P12019">cAMP phosphodiesterases class-II</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12429832">12429832</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>168</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.4.53"><B>3.1.4.53</B></A></td>
|
||
<td>3',5'-cyclic-AMP phosphodiesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q23917">Q23917</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q23917">PDE2_DICDI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2HD1">2HD1</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2HD1">HD-domain/PDEase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q23917">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q23917">3'5'-cyclic nucleotide phosphodiesterase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9812977,10488068">9812977, 10488068</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.4.53"><B>3.1.4.53</B></A></td>
|
||
<td>3',5'-cyclic-AMP phosphodiesterase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P12019">P12019</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P12019">PDE1_DICDI</A></td>
|
||
<td>similar to: <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1KO2">1KO2</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1KO2">Metallo-hydrolase/oxidoreductase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P12019">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P12019">cAMP phosphodiesterases class-II</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12429832">12429832</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>169</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.13.4"><B>3.1.13.4</B></A></td>
|
||
<td>Poly(A)-specific ribonuclease</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q504Q3">Q504Q3</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q504Q3">PAN2_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1WLJ">1WLJ</A> (domain)</td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1WLJ">Ribonuclease H-like motif</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q504Q3">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q504Q3">DnaQ-like 3'-5' exonuclease, Exonuc X-T</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/14583602">14583602</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.13.4"><B>3.1.13.4</B></A></td>
|
||
<td>Poly(A)-specific ribonuclease</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P31384">P31384</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P31384">CCR4_YEAST</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1AKO">1AKO</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1AKO">DNase I-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P31384">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P31384">Endonuclease/Exonuclease/phosphatase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11889048,11889047">11889048, 11889047</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>170</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.3"><B>3.2.1.3</B></A></td>
|
||
<td>Glucan 1,4-alpha-glucosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P69328">P69328</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P69328">AMYG_ASPNG</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1GAI">1GAI</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1GAI">Alpha/alpha toroid</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P69328">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P69328">Glycosyl hydrolases family 15</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1527049,8503847,3081341">1527049, 8503847, 3081341</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.3"><B>3.2.1.3</B></A></td>
|
||
<td>Glucan 1,4-alpha-glucosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O43451">O43451</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O43451">MGA_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2QLY">2QLY</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1ZY9">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O43451">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O43451">Glycosyl hydrolases family 31</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/18036614,3143729">18036614, 3143729</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>171</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.11"><B>3.2.1.11</B></A></td>
|
||
<td>Dextranase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P48845">P48845</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P48845">DEXT_PENMI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1OGM">1OGM</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1OGM">Dextranase N-terminal domain and Single-stranded right-handed beta-helix</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P48845">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P48845">Glycosyl hydrolases family 28</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8905923,12962629">8905923, 12962629</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.11"><B>3.2.1.11</B></A></td>
|
||
<td>Dextranase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P39653">P39653</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P39653">DEXT_STRDO</A></td>
|
||
<td>similar to: <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1EA9">1EA9</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1EA9">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P39653">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P39653">Glycosyl hydrolase 66 family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8021165,12030973">8021165, 12030973</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>172</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.45"><B>3.2.1.45</B></A></td>
|
||
<td>Glucosylceramidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P04062">P04062</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P04062">GLCM_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2V3D">2V3D</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2V3D">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P04062">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P04062">O-Glycosyl hydrolase family 30</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/17666401">17666401</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.45"><B>3.2.1.45</B></A></td>
|
||
<td>Glucosylceramidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9HCG7">Q9HCG7</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9HCG7">GBA2_HUMAN</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2JG0">2JG0</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2JG0">Alpha/alpha toroid</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9HCG7">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9HCG7">DUF608, Protein of unknown function</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11489889">11489889</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>173</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.51"><B>3.2.1.51</B></A></td>
|
||
<td>Alpha-L-fucosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P04066">P04066</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P04066">FUCO_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ODU">1ODU</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1ODU">Glycosyl_hydrolase_domain and TIM_beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P04066">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P04066">Glycosyl hydrolase 29 family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2894306,2174090">2894306, 2174090</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.51"><B>3.2.1.51</B></A></td>
|
||
<td>Alpha-L-fucosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9FXE5">Q9FXE5</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9FXE5">FUCO3_ARATH</A></td>
|
||
<td>Predicted: <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ESC">1ESC</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1ESC">Flavodoxin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9FXE5">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9FXE5">GDSL' lipolytic enzyme</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11788770">11788770</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.51"><B>3.2.1.51</B></A></td>
|
||
<td>Alpha-L-fucosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q8L7W8">Q8L7W8</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q8L7W8">FUCO2_ARATH</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2RDY">2RDY</A></td>
|
||
<td>Predicted: Alpha/alpha toroid</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q8L7W8">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q8L7W8">Glycosyl hydrolase 95 family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15262925">15262925</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>174</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.58"><B>3.2.1.58</B></A></td>
|
||
<td>Glucan 1,3-<2D>-glucosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P29717">P29717</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P29717">EXG_CANAL</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1CZ1">1CZ1</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1CZ1">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P29717">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P29717">Glycosyl hydrolase family 5 (cellulase A)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8436950,10610795">8436950, 10610795</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.58"><B>3.2.1.58</B></A></td>
|
||
<td>Glucan 1,3-<2D>-glucosidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P49426">P49426</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P49426">EXG1_COCCA</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3EQN">3EQN</A>, <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1KTW">1KTW</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1KTW">Single-stranded right-handed beta-helix</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P49426">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P49426">Glycosyl hydrolase family 55</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8135518">8135518</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>175</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.81"><B>3.2.1.81</B></A></td>
|
||
<td><EFBFBD>-agarase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P07883">P07883</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P07883">AGAR_STRCO</A></td>
|
||
<td>-</td>
|
||
<td>Predicted: Concanavalin A-like lectins/glucanases</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P07883">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P07883">Glycosyl hydrolase family 16</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3034860">3034860</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.81"><B>3.2.1.81</B></A></td>
|
||
<td><EFBFBD>-agarase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P48839">P48839</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P48839">AGAA_VIBS7</A></td>
|
||
<td>-</td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QOX">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P48839">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P48839">Glycosyl hydrolase family 50</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8285681">8285681</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>176</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.96"><B>3.2.1.96</B></A></td>
|
||
<td>Mannosyl-glycoprotein endo-<2D>-N-acetylglucosaminidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P59206">P59206</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P59206">LYTB_STRR6</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2ZYC">2ZYC</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2F32">Lysozyme-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P59206">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P59206">Glucosaminidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10096093">10096093</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.96"><B>3.2.1.96</B></A></td>
|
||
<td>Mannosyl-glycoprotein endo-<2D>-N-acetylglucosaminidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P36912">P36912</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P36912">EBA2_FLAME</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1EOK">1EOK</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1EOK">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P36912">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P36912">Glycosyl hydrolase 18 family (UniProt)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8486657,7768917">8486657, 7768917</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>177</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.2.22"><B>3.2.2.22</B></A></td>
|
||
<td>rRNA N-glycosylase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P02879">P02879</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P02879">RICI_RICCO</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1APG">1APG</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1UQ5">Ribosome inactivating proteins (RIP)</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P02879">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P02879">Ribosome inactivating protein</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1433290,8780513">1433290, 8780513</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.2.22"><B>3.2.2.22</B></A></td>
|
||
<td>rRNA N-glycosylase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q1JPL7">Q1JPL7</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q1JPL7">PME18_ARATH</A></td>
|
||
<td>Predicted: <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1X8Z">1X8Z</A>, <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1GQ8">1GQ8</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1X8Z">Bromodomain-like (N-term) and Single-stranded right-handed beta-helix (C-term)</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q1JPL7">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q1JPL7">PMEI, Plant invertase/pectin methylesterase inhibitor and pectinesterase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/18222123">18222123</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>178</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.1.28"><B>3.5.1.28</B></A></td>
|
||
<td>N-acetylmuramoyl-L-alanine amidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P13016">P13016</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P13016">AMPD_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1J3G">1J3G</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1J3G">N-acetylmuramoyl-L-alanine amidase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P13016">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P13016">N-acetylmuramoyl-L-alanine amidase 2</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12654266">12654266</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.1.28"><B>3.5.1.28</B></A></td>
|
||
<td>N-acetylmuramoyl-L-alanine amidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P26365">P26365</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P26365">AMIB_ECOLI</A></td>
|
||
<td>C-term is similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1JWQ">1JWQ</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1JWQ">Phosphorylase/hydrolase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P26365">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P26365">Zn-dependent exopeptidases</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7511774">7511774</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>179</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.6"><B>3.6.1.6</B></A></td>
|
||
<td>Nucleoside-diphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9WUZ9">Q9WUZ9</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9WUZ9">ENTP5_MOUSE</A></td>
|
||
<td>similar to N-term of <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3CJ1">3CJ1</A></td>
|
||
<td>Predicted: Ribonuclease H-like motif</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9WUZ9">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9WUZ9">GDA1/CD39 NTPase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10369669">10369669</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.6"><B>3.6.1.6</B></A></td>
|
||
<td>Nucleoside-diphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q8WVQ1">Q8WVQ1</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q8WVQ1">CANT1_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2H2N">2H2N</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2H2N">5-bladed beta-propeller</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q8WVQ1">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q8WVQ1">Apyrase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12167635">12167635</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>180</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.1.1.22"><B>4.1.1.22</B></A></td>
|
||
<td>Histidine decarboxylase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P28577">P28577</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P28577">DCHS_ENTAE</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1JS3">1JS3</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1JS3">PLP-dependent transferase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P28577">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P28577">Pyridoxal-dependent decarboxylase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2033044">2033044</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.1.1.22"><B>4.1.1.22</B></A></td>
|
||
<td>Histidine decarboxylase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P00862">P00862</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P00862">DCHS_LACS3</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1HQ6">1HQ6</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1HQ6">Pyruvoyl-dependent histidine and arginine decarboxylases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P00862">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P00862">Histidine decarboxylase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2857718">2857718</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>181</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.2.3"><B>4.2.2.3</B></A></td>
|
||
<td>Poly(<28>-D-mannuronate) lyase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P59786">P59786</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P59786">ALGL_PSEFL</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1QAZ">1QAZ</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QAZ">Alpha/alpha toroid</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P59786">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P59786">Chondroitin AC/alginate lyase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12775688">12775688</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.2.3"><B>4.2.2.3</B></A></td>
|
||
<td>Poly(<28>-D-mannuronate) lyase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q59478">Q59478</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q59478">ALYA_KLEPN</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1VAV">1VAV</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1VAV">Concanavalin A-like lectins/glucanases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q59478">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q59478">Concanavalin A-like lectins/glucanases</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8200539">8200539</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.2.3"><B>4.2.2.3</B></A></td>
|
||
<td>Poly(<28>-D-mannuronate) lyase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q06365">Q06365</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q06365">ALYP_PSESO</A></td>
|
||
<td>N-term is similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1OFM">1OFM</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1OFM">Single-stranded right-handed beta-helix</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q06365">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q06365">Polysaccharide lyase 6 (UniProt)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8336113,8319887">8336113, 8319887</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>182</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.2.9"><B>4.2.2.9</B></A></td>
|
||
<td>Pectate disaccharide-lyase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q05526">Q05526</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q05526">PELW_DICD3</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2V8J">2V8J</A>, similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1FP3">1FP3</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1FP3">Alpha/alpha toroid</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q05526">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q05526">Periplasmic pectate lyase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10383957,1766386,17881361">10383957, 1766386, 17881361</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.2.2.9"><B>4.2.2.9</B></A></td>
|
||
<td>Pectate disaccharide-lyase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P22751">P22751</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P22751">PELX_ERWCH</A></td>
|
||
<td>C-term is similar to C-term of <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1RU4">1RU4</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1RU4">Single-stranded right-handed beta-helix</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P22751">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P22751">Polysaccharide lyase 9 (UniProt)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10383957,2254266">10383957, 2254266</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>183</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.3.1.18"><B>4.3.1.18</B></A></td>
|
||
<td>D-serine ammonia-lyase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P00926">P00926</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P00926">SDHD_ECOLI</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1O58">1O58</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1O58">Tryptophan synthase beta subunit-like PLP-dependent enzymes</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P00926">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P00926">Pyridoxal-phosphate dependent enzyme</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/6853521,10601247">6853521, 10601247</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.3.1.18"><B>4.3.1.18</B></A></td>
|
||
<td>D-serine ammonia-lyase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P53095">P53095</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P53095">YGU6_YEAST</A></td>
|
||
<td>Predicted: <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1L6G">1L6G</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1L6G">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P53095">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P53095">Alanine racemase, N-terminal domain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/17937657,18564178">17937657, 18564178</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>184</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.99.1.4"><B>4.99.1.4</B></A></td>
|
||
<td>Sirohydrochlorin ferrochelatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0AEA8">P0AEA8</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0AEA8">CYSG_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1PJT">1PJT</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1PJT">Rossmann-fold, Siroheme synthase middle domains-like and Tetrapyrrole methylase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0AEA8">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0AEA8">Siroheme synthase (multi doman)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8243665,2407558,2407234">8243665, 2407558, 2407234</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.99.1.4"><B>4.99.1.4</B></A></td>
|
||
<td>Sirohydrochlorin ferrochelatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P61817">P61817</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P61817">SIRB_BACME</A></td>
|
||
<td>Predicted: <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1tjn">1tjn</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1tjn">Chelatase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P61817">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P61817">CbiX family, SirB subfamily</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12408752">12408752</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>185</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.3.3.1"><B>5.3.3.1</B></A></td>
|
||
<td>Steroid delta-isomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P00947">P00947</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P00947">SDIS_COMTE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1OCV">1OCV</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1OCV">Cystatin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P00947">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P00947">Nuclear transport factor 2</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/4753764,10551849">4753764, 10551849</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.3.3.1"><B>5.3.3.1</B></A></td>
|
||
<td>Steroid delta-isomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P14060">P14060</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P14060">3BHS1_HUMAN</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1EQ2">1EQ2</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1EQ2">Rossmann-fold</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P14060">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P14060">3-beta hydroxysteroid dehydrogenase/isomerase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2139411,2082186,1401999">2139411, 2082186, 1401999</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>186</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.3.3.12"><B>5.3.3.12</B></A></td>
|
||
<td>L-dopachrome isomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P40126">P40126</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P40126">TYRP2_HUMAN</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1WX2">1WX2</A>, <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1LNL">1LNL</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1LNL">Di-copper centre-containing domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P40126">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P40126">Tyrosinase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8573077">8573077</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.3.3.12"><B>5.3.3.12</B></A></td>
|
||
<td>L-dopachrome isomerase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P34884">P34884</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P34884">MIF_MOUSE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2GDG">2GDG</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2GDG">Tautomerase/MIF</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P34884">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P34884">Macrophage migration inhibitory factor (MIF)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7947826,10360941,8900542,9794786">7947826, 10360941, 8900542, 9794786</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>187</td>
|
||
<td>no EC</td>
|
||
<td>4-Methyl-5-hydroxyethylthiazole phosphate synthase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P30139">P30139</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P30139">THIG_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1XM3">1XM3</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1XM3">TIM beta/alpha-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P30139">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P30139">Thiazole biosynthesis protein</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/17403671,15012138">17403671, 15012138</A></td>
|
||
<td>Predicted analogs (no EC)</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td>no EC</td>
|
||
<td>4-Methyl-5-hydroxyethylthiazole phosphate synthase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P32318">P32318</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P32318">THI4_YEAST</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2GJC">2GJC</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2GJC">FAD/NAD(P)-binding domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P32318">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P32318">Thi4 family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9367751,12794638,18652458">9367751, 12794638, 18652458</A></td>
|
||
<td>Predicted analogs (no EC)</td>
|
||
</TR>
|
||
|
||
<TR bgColor=#99cc66>
|
||
<TD vAlign=top width="5%"><FONT size=+1><B>No.</B></FONT></TD>
|
||
<TD vAlign=top width="5%"><FONT size=+1><B>EC no.</B></CENTER></FONT></TD>
|
||
<TD vAlign=top width="15%"><FONT size=+1><B>Enzyme name</B></FONT></TD>
|
||
<TD vAlign=top width="5%"><FONT size=+1><B>NCBI</B></FONT></TD>
|
||
<TD vAlign=top width="5%"><FONT size=+1><B>UniProt</B></FONT></FONT></TD>
|
||
<TD vAlign=top width="5%"><FONT size=+1><B>PDB</B></FONT></TD>
|
||
<TD vAlign=top width="15%"><FONT size=+1><B>SCOP fold</B></FONT></TD>
|
||
<TD vAlign=top width="5%"><FONT size=+1><B>Super-family</B></FONT></TD>
|
||
<TD vAlign=top width="15%"><FONT size=+1><B>Family (Pfam)</B></FONT></TD>
|
||
<TD vAlign=top width="10%"><FONT size=+1><B>Ref.</B></FONT></TD>
|
||
<TD vAlign=top width="15%"><FONT size=+1><B>Potential</B></FONT></TD>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>188</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.1.1.81"><B>1.1.1.81</B></A></td>
|
||
<td>Hydroxypyruvate reductase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P70788">P70788</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P70788">TTUD3_AGRVI</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2B8N">2B8N</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2B8N">GckA/TtuD-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P70788">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P70788">MOFRL</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8672817,7592429">8672817, 7592429</A></td>
|
||
<td>Potential analogs (mis-annotation)</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.1.1.81"><B>1.1.1.81</B></A></td>
|
||
<td>Hydroxypyruvate reductase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P37666">P37666</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P37666">GHRB_ECOLI</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2DBR">2DBR</A>, <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1GDH">1GDH</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1GDH">Rossmann-fold and Flavodoxin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P37666">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P37666">D-isomer specific 2-hydroxyacid dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11237876">11237876</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>189</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.1.5.2"><B>1.1.5.2</B></A></td>
|
||
<td>Quinoprotein glucose dehydrogenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P05465">P05465</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P05465">DHGA_ACICA</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1KV9">1KV9</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1KV9">8-bladed beta-propeller and Cytochrome c</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P05465">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P05465">Bacterial PQQ dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3399393,16754970">3399393, 16754970</A></td>
|
||
<td>Potential analogs (related structures)</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.1.5.2"><B>1.1.5.2</B></A></td>
|
||
<td>Quinoprotein glucose dehydrogenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P13650">P13650</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P13650">DHGB_ACICA</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1CRU">1CRU</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1CRU">6-bladed beta-propeller</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P13650">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P13650">PQQ oxidoreductase gdhB</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/14741705">14741705</A></td>
|
||
<td>Potential analogs (related structures)</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>190</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.4.1.2"><B>1.4.1.2</B></A></td>
|
||
<td>Glutamate dehydrogenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P41755">P41755</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P41755">DHE2_ACHKL</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P41755">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P41755">NAD-specific glutamate dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8308022">8308022</A></td>
|
||
<td>Potential analogs (no papers after 1994)</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.4.1.2"><B>1.4.1.2</B></A></td>
|
||
<td>Glutamate dehydrogenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P39633">P39633</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P39633">DHE2_BACSU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1GTM">1GTM</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1GTM">Rossmann-fold and Aminoacid dehydrogenase-like N-terminal domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P39633">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P39633">Glu/Leu/Phe/Val dehydrogenases family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9829940">9829940</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>191</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.13.11.15"><B>1.13.11.15</B></A></td>
|
||
<td>3,4-dihydroxyphenylacetate 2,3-dioxygenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q45135">Q45135</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q45135">Q45135_9MICO</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1F1X">1F1X</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1F1X">Glyoxalase/Bleomycin resistance protein/ Dihydroxybiphenyl dioxygenase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q45135">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q45135">Glyoxalase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9179284,15028678,15568806,16217642">9179284, 15028678, 15568806, 16217642</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.13.11.15"><B>1.13.11.15</B></A></td>
|
||
<td>3,4-dihydroxyphenylacetate 2,3-dioxygenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q05353">Q05353</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q05353">HPCB_ECOLI</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q05353">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q05353">LigB</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3053656,2261999">3053656, 2261999</A></td>
|
||
<td>Potential analogs (Fe dependent)</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>192</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.14.11.16"><B>1.14.11.16</B></A></td>
|
||
<td>Peptide-aspartate <20>-dioxygenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9NWT6">Q9NWT6</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9NWT6">HIF1N_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1H2K">1H2K</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1H2K">Double-stranded beta-helix and Transactivation domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9NWT6">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9NWT6">JmjC domain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12042299,12080085,12432100">12042299, 12080085, 12432100</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.14.11.16"><B>1.14.11.16</B></A></td>
|
||
<td>Peptide-aspartate <20>-dioxygenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q12797">Q12797</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q12797">ASPH_HUMAN</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q12797">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q12797">Aspartyl/asparaginyl beta-hydroxylase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7821814">7821814</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>193</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.14.13.7"><B>1.14.13.7</B></A></td>
|
||
<td>Phenol 2-monooxygenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P19730">P19730</A>, <A href="https://www.ncbi.nlm.nih.gov/protein/P19731">P19731</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P19730">DMPL_PSEUF</A><BR> <A href="http://www.uniprot.org/uniprot/P19731">DMPM_PSEUF</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2INP">2INP</A>, <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1HQI">1HQI</A></A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2IND">Ferritin-like and beta-Grasp (ubiquitin-like)</A> and <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1HQI">Monooxygenase (hydroxylase) regulatory protein</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P19731">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P19731">Methane/Phenol/Toluene Hydroxylase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/17176061,2254258">17176061, 2254258</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.14.13.7"><B>1.14.13.7</B></A></td>
|
||
<td>Phenol 2-monooxygenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P15245">P15245</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P15245">PH2M_TRICU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1FOH">1FOH</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1FOH">FAD/NADP-binding domain, Thioredoxin fold and FAD-linked_reductases C-terminal domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P15245">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P15245">Pfam hit</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8145253,9634698">8145253, 9634698</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>194</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.14.15.3"><B>1.14.15.3</B></A></td>
|
||
<td>Alkane 1-monooxygenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P12691">P12691</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P12691">ALKB_PSEOL</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P12691">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P12691">Fatty acid desaturase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/2647718">2647718</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.14.15.3"><B>1.14.15.3</B></A></td>
|
||
<td>Alkane 1-monooxygenase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q5TCH4">Q5TCH4</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q5TCH4">CP4AM_HUMAN</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1TQN">1TQN</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1TQN">Cytochrome P450</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q5TCH4">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q5TCH4">Cytochrome P450</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/14641109,7798189,11931657,2361958">14641109, 7798189, 11931657, 2361958</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>195</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.1.23"><B>2.3.1.23</B></A></td>
|
||
<td>1-acylglycerophosphocholine O-acyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O42916">O42916</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O42916">ALE1_SCHPO</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O42916">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O42916">MBOAT family, integral membrane protein</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/17890783">17890783</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.1.23"><B>2.3.1.23</B></A></td>
|
||
<td>1-acylglycerophosphocholine O-acyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q06510">Q06510</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q06510">TAZ1_YEAST</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1IUQ">1IUQ</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1IUQ">Glycerol-3-phosphate (1)-acyltransferase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q06510">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q06510">Acyltransferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15588229,16135531">15588229, 16135531</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>196</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.1.75"><B>2.3.1.75</B></A></td>
|
||
<td>Long-chain-alcohol O-fatty-acyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q93ZR6">Q93ZR6</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q93ZR6">WSD1_ARATH</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q93ZR6">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q93ZR6">N-term UPF0089 family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/18621978">18621978</A></td>
|
||
<td>Potential analogs (activity?)</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.1.75"><B>2.3.1.75</B></A></td>
|
||
<td>Long-chain-alcohol O-fatty-acyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9XGY6">Q9XGY6</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9XGY6">WAXS1_SIMCH</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9XGY6">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9XGY6">Wax synthase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10712527">10712527</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.1.75"><B>2.3.1.75</B></A></td>
|
||
<td>Long-chain-alcohol O-fatty-acyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q58HT5">Q58HT5</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q58HT5">AWAT1_HUMAN</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q58HT5">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q58HT5">Diacylglycerol acyltransferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15671038">15671038</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>197</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.1.88"><B>2.3.1.88</B></A></td>
|
||
<td>Peptide alpha-N-acetyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P41227">P41227</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P41227">ARD1A_HUMAN</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1MK4">1MK4</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1MK4">Acyl-CoA N-acyltransferases (Nat)</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P41227">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P41227">GNAT superfamily</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7981673,15496142">7981673, 15496142</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.1.88"><B>2.3.1.88</B></A></td>
|
||
<td>Peptide alpha-N-acetyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P37293">P37293</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P37293">NAT2_YEAST</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P37293">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P37293">No Pfam hits</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8175741,9128142">8175741, 9128142</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>198</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.2.13"><B>2.3.2.13</B></A></td>
|
||
<td>Protein-glutamine gamma-glutamyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P00488">P00488</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P00488">F13A_HUMAN</A>, <A href="http://www.uniprot.org/uniprot/P81453">TGAS_STRMB</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1FIE">1FIE</A>, <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1IU4">1IU4</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1IU4">Cysteine proteinases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P00488">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P00488">Transglutaminase, microbial transglutaminase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9839945,2901091,2877456">9839945, 2901091, 2877456</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.3.2.13"><B>2.3.2.13</B></A></td>
|
||
<td>Protein-glutamine gamma-glutamyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P40746">P40746</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P40746">TGL_BACSU</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P40746">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P40746">Bacillus TGase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9692191">9692191</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>199</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.4.1.69"><B>2.4.1.69</B></A></td>
|
||
<td>Galactoside 2-alpha-L-fucosyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9TUD4">Q9TUD4</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9TUD4">FUT1_GORGO</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9TUD4">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9TUD4">Glycosyltransferase family 11</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10723735,7372640,8613146">10723735, 7372640, 8613146</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.4.1.69"><B>2.4.1.69</B></A></td>
|
||
<td>Galactoside 2-alpha-L-fucosyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9M5Q1">Q9M5Q1</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9M5Q1">FUT1_PEA</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9M5Q1">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9M5Q1">Xyloglucan fucosyltransferase (Glycosyltransferase family 37)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10747946">10747946</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.4.1.69"><B>2.4.1.69</B></A></td>
|
||
<td>Galactoside 2-alpha-L-fucosyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q54QG0">Q54QG0</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q54QG0">PGFB_DICDI</A></td>
|
||
<td>N-term is similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1H7Q">1H7Q</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1H7Q">Nucleotide-diphospho-sugar transferases (N-term)</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q54QG0">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q54QG0">Glycosyltransferase family 2 (UniProt)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11423539,12244067">11423539, 12244067</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>200</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.4.1.226"><B>2.4.1.226</B></A></td>
|
||
<td>N-acetylgalactosaminyl-proteoglycan 3-<2D>-glucuronosyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q8IZ52">Q8IZ52</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q8IZ52">CHSS2_HUMAN</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q8IZ52">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q8IZ52">Chondroitin N-acetylgalactosaminyl-transferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12761225">12761225</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.4.1.226"><B>2.4.1.226</B></A></td>
|
||
<td>N-acetylgalactosaminyl-proteoglycan 3-<2D>-glucuronosyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q8L0V4">Q8L0V4</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q8L0V4">CHS_ECOLX</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2Z86">2Z86</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1H7Q">Nucleotide-diphospho-sugar transferases (N-term and C-term)</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q8L0V4">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q8L0V4">Glycosyltransferase 2</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11943778">11943778</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>201</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.7.24"><B>2.7.7.24</B></A></td>
|
||
<td>Glucose-1-phosphate thymidylyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P61887">P61887</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P61887">RMLA2_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1MC3">1MC3</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1MC3">Nucleotide-diphospho-sugar transferases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P61887">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P61887">Nucleotidyl transferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7559340,12171937">7559340, 12171937</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.7.24"><B>2.7.7.24</B></A></td>
|
||
<td>Glucose-1-phosphate thymidylyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P29785">P29785</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P29785">STRO_STRGR</A></td>
|
||
<td>Predicted: <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1LBV">1LBV</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1LBV">Carbohydrate phosphatase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P29785">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P29785">Inositol monophosphatase family</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1661369">1661369</A></td>
|
||
<td>Potential analogs (activity?)</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>202</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.7.50"><B>2.7.7.50</B></A></td>
|
||
<td>mRNA guanylyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q01159">Q01159</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q01159">MCE1_YEAST</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1P16">1P16</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1P16">ATP-grasp</A> (catalytic domain)</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q01159">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q01159">Eukaryotic GTase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/6389537,3029058,6094533">6389537, 3029058, 6094533</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.7.50"><B>2.7.7.50</B></A></td>
|
||
<td>mRNA guanylyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P11079">P11079</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P11079">LMBD2_REOVD</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1EJ6">1EJ6</A></td>
|
||
<td>Low-resolution structure 1EJ6 does not allow comparison</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P11079">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P11079">Orthoreovirus lambda-2</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10801118">10801118</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.7.50"><B>2.7.7.50</B></A></td>
|
||
<td>mRNA guanylyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/A2T3S5">A2T3S5</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/A2T3S5">VP3_ROTSH</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=A2T3S5">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/A2T3S5">Rotavirus VP3</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10603323">10603323</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>203</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.8.5"><B>2.7.8.5</B></A></td>
|
||
<td>CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P25578">P25578</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P25578">PGPS1_YEAST</A></td>
|
||
<td>Predicted: <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1BYS">1BYS</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1BYS">Phospholipase D/ nuclease</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P25578">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P25578">Phospholipase D (CDP-alcohol phosphatidyltransferase class-I, UniProt)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9545322">9545322</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.8.5"><B>2.7.8.5</B></A></td>
|
||
<td>CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0ABF8">P0ABF8</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0ABF8">PGSA_ECOLI</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0ABF8">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0ABF8">CDP-alcohol phosphatidyltransferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1323047,8195097">1323047, 8195097</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>204</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.8.8"><B>2.7.8.8</B></A></td>
|
||
<td>CDP-diacylglycerol-serine O-phosphatidyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P23830">P23830</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P23830">PSS_ECOLI</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1BYR">1BYR</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1BYR">Phospholipase D/ nuclease</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P23830">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P23830">Phospholipase D Active site motif</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1323044,10074947">1323044, 10074947</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.8.8"><B>2.7.8.8</B></A></td>
|
||
<td>CDP-diacylglycerol-serine O-phosphatidyltransferase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P08456">P08456</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P08456">PSS_YEAST</A></td>
|
||
<td>-</td>
|
||
<td>Integral membrane protein</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P08456">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P08456">CDP-alcohol phosphatidyltransferase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3040403">3040403</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>205</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.13.3"><B>2.7.13.3</B></A></td>
|
||
<td>Histidine kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0AEJ4">P0AEJ4</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0AEJ4">ENVZ_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1BXD">1BXD</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1BXD">ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0AEJ4">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0AEJ4">Histidine kinase domain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10426948,1323560">10426948, 1323560</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.13.3"><B>2.7.13.3</B></A></td>
|
||
<td>Histidine kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9AWA5">Q9AWA5</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9AWA5">GWD1_SOLTU</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9AWA5">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9AWA5">Pyruvate phosphate dikinase, PEP/pyruvate binding domain</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12011472">12011472</A></td>
|
||
<td>Potential analogs (chloroplast precursor)</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>206</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.32"><B>3.1.1.32</B></A></td>
|
||
<td>Phospholipase A1</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A921">P0A921</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A921">PA1_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1QD5">1QD5</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QD5">Transmembrane beta-barrels</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A921">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A921">Phospholipase A1</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8300539">8300539</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.1.32"><B>3.1.1.32</B></A></td>
|
||
<td>Phospholipase A1</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P18952">P18952</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P18952">PA1_SERLI</A></td>
|
||
<td>-</td>
|
||
<td>Predicted: Alpha/beta hydrolase</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P18952">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P18952">Pfam hit</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/3056919">3056919</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>207</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.6"><B>3.1.3.6</B></A></td>
|
||
<td>3'-nucleotidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A840">P0A840</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A840">SURE_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ILV">1ILV</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1ILV">SurE-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A840">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A840">SurE nucleotidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15489502">15489502</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.6"><B>3.1.3.6</B></A></td>
|
||
<td>3'-nucleotidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P24504">P24504</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P24504">NUP3_PENSQ</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1AK0">1AK0</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1AK0">Phospholipase C/P1 nuclease</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P24504">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P24504">S1/P1 Nuclease</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1964878,1369324">1964878, 1369324</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>20</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.78"><B>3.1.3.78</B></A></td>
|
||
<td>Phosphatidylinositol-4,5-bisphosphate 4-phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q86T03">Q86T03</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q86T03">TM55B_HUMAN</A>)</td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q86T03">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q86T03">Transmembrane protein 55A</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16365287">16365287</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.78"><B>3.1.3.78</B></A></td>
|
||
<td>Phosphatidylinositol-4,5-bisphosphate 4-phosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q07566">Q07566</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q07566">IPGD_SHIFL</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q07566">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q07566">Enterobacterial virulence protein IpgD</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/12356723,11029686">12356723, 11029686</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>209</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.132"><B>3.2.1.132</B></A></td>
|
||
<td>Chitosanase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9P961">Q9P961</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9P961">Q9P961_ASPOR</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9P961">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9P961">Fungal chitosanase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11388486">11388486</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.132"><B>3.2.1.132</B></A></td>
|
||
<td>Chitosanase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O07921">O07921</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O07921">CHIS_BACSU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1CHK">1CHK</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1CHK">Lysozyme-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O07921">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O07921">Glycosyl hydrolase family 46</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10658653,10521473">10658653, 10521473</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>210</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.143"><B>3.2.1.143</B></A></td>
|
||
<td>Poly(ADP-ribose) glycohydrolase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9NX46">Q9NX46</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9NX46">ARHL2_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2FOZ">2FOZ</A>, similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1T5J">1T5J</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1T5J">ADP-ribosylglycohydrolase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9NX46">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9NX46">ADP-ribosylglycohydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16278211">16278211</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.143"><B>3.2.1.143</B></A></td>
|
||
<td>Poly(ADP-ribose) glycohydrolase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q86W56">Q86W56</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q86W56">PARG_HUMAN</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q86W56">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q86W56">Poly (ADP-ribose) glycohydrolase (PARG)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10449915,9115250">10449915, 9115250</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>211</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.2.5"><B>3.2.2.5</B></A></td>
|
||
<td>NAD<sup>+</sup> nucleosidase (ADP ribosyl cyclase)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P28907">P28907</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P28907">CD38_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2EF1">2EF1</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2EF1">Flavodoxin-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P28907">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P28907">Ribosyl hydrolyase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8253715,16154090">8253715, 16154090</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.2.5"><B>3.2.2.5</B></A></td>
|
||
<td>NAD<sup>+</sup> nucleosidase (ADP ribosyl cyclase)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/A2RCA5">A2RCA5</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/A2RCA5">A2RCA5_STRPG</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=A2RCA5">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/A2RCA5">NAD glycohydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15627505,16177331,18048938">15627505, 16177331, 18048938</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=3>212</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.1.23"><B>3.5.1.23</B></A></td>
|
||
<td>Ceramidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q13510">Q13510</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q13510">ASAH1_HUMAN</A></td>
|
||
<td>Predicted: <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3PVA">3PVA</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=3PVA">Ntn hydrolase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q13510">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q13510">Choloylglycine hydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7744740,8955159,10993717">7744740, 8955159, 10993717</A></td>
|
||
<td>Potential analogs (acid)</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.1.23"><B>3.5.1.23</B></A></td>
|
||
<td>Ceramidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q5QJU3">Q5QJU3</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q5QJU3">ASA3L_HUMAN</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q5QJU3">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q5QJU3">Alkaline phytoceramidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11356846">11356846</A></td>
|
||
<td>Potential analogs (alkaline)</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.1.23"><B>3.5.1.23</B></A></td>
|
||
<td>Ceramidase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9NR71">Q9NR71</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9NR71">ASAH2_HUMAN</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2ZXC">2ZXC</A></td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9NR71">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9NR71">Neutral/alkaline non-lysosomal ceramidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10781606,16229686">10781606, 16229686</A></td>
|
||
<td>Potential analogs (neutral)</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>213</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.27"><B>3.6.1.27</B></A></td>
|
||
<td>Undecaprenyl-diphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P80143">P80143</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P80143">UDDP_SULAC</A></td>
|
||
<td>C-term is similar to C-term of <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1QI9">1QI9</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QI9">Acid phosphatase/ Vanadium-dependent haloperoxidase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P80143">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P80143">PAP2 superfamily</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1321720">1321720</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.6.1.27"><B>3.6.1.27</B></A></td>
|
||
<td>Undecaprenyl-diphosphatase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P60932">P60932</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P60932">UPPP_ECOLI</A></td>
|
||
<td>-</td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P60932">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P60932">Bacitracin resistance protein BacA</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15778224">15778224</A></td>
|
||
<td>Potential analogs</td>
|
||
</TR>
|
||
|
||
<TR bgColor=#99cc66>
|
||
<TD vAlign=top width="5%"><FONT size=+1><B>No.</B></FONT></TD>
|
||
<TD vAlign=top width="5%"><FONT size=+1><B>EC no.</B></CENTER></FONT></TD>
|
||
<TD vAlign=top width="15%"><FONT size=+1><B>Enzyme name and REACTION</B></FONT></TD>
|
||
<TD vAlign=top width="5%"><FONT size=+1><B>NCBI</B></FONT></TD>
|
||
<TD vAlign=top width="5%"><FONT size=+1><B>UniProt</B></FONT></FONT></TD>
|
||
<TD vAlign=top width="5%"><FONT size=+1><B>PDB</B></FONT></TD>
|
||
<TD vAlign=top width="15%"><FONT size=+1><B>SCOP fold</B></FONT></TD>
|
||
<TD vAlign=top width="5%"><FONT size=+1><B>Super-family</B></FONT></TD>
|
||
<TD vAlign=top width="15%"><FONT size=+1><B>Family (Pfam)</B></FONT></TD>
|
||
<TD vAlign=top width="10%"><FONT size=+1><B>Ref.</B></FONT></TD>
|
||
<TD vAlign=top width="15%"><FONT size=+1><B>Comments</B></FONT></TD>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>214</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.1.1.11"><B>4.1.1.11</B></A></td>
|
||
<td>Aspartate 1-decarboxylase (L-Aspartate <=> <20>-Alanine + CO<sub>2</sub>)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A790">P0A790</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A790">PAND_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1AW8">1AW8</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1AW8">Double psi beta-barrel</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A790">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A790">Aspartate decarboxylase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/6767707">6767707</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/4.1.1.15"><B>4.1.1.15</B></A></td>
|
||
<td>Glutamate decarboxylase (L-Aspartate <=> <20>-Alanine + CO<sub>2</sub>)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q05329">Q05329</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q05329">DCE2_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1JS3">1JS3</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1JS3">PLP-dependent transferase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q05329">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q05329">Pyridoxal-dependent decarboxylase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/6956856,658037">6956856, 658037</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>215</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.4.3.21"><B>1.4.3.21</B></A></td>
|
||
<td>Primary-amine oxidase (Tyramine + H<sub>2</sub>O + Oxygen <=> 4-Hydroxyphenylacetaldehyde + NH<sub>3</sub> + H<sub>2</sub>O<sub>2</sub>)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P49250">P49250</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P49250">AMO_KLEAE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1OAC">1OAC</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1OAC">Supersandwich and Cystatin-like and N domain of copper amine oxidase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P49250">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P49250">Copper amine oxidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1556068">1556068</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.4.3.4"><B>1.4.3.4</B></A></td>
|
||
<td>Amine oxidase (flavin-containing) (Tyramine + H<sub>2</sub>O + Oxygen <=> 4-Hydroxyphenylacetaldehyde + NH<sub>3</sub> + H<sub>2</sub>O<sub>2</sub>)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q6NSN2">Q6NSN2</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q6NSN2">AOF_DANRE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1O5W">1O5W</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1O5W">FAD/NADP-binding domain and FAD-linked reductases C-terminal domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q6NSN2">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q6NSN2">Flavin monoamine oxidase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16917825">16917825</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>216</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.4.14"><B>2.7.4.14</B></A></td>
|
||
<td>Cytidylate kinase (ATP + UMP <=> ADP + UDP)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q5EBM0">Q5EBM0</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q5EBM0">CMPK2_HUMAN</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2TMK">2TMK</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2TMK">P-loop containing NTPases</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q5EBM0">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q5EBM0">Thymidylate kinase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/17999954">17999954</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.4.22"><B>2.7.4.22</B></A></td>
|
||
<td>UMP kinase (ATP + UMP <=> ADP + UDP)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A7E9">P0A7E9</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A7E9">PYRH_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2BNE">2BNE</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2BNE">Carbamate kinase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A7E9">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A7E9">Amino acid kinase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7711027">7711027</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>217</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.62"><B>3.1.3.62</B></A></td>
|
||
<td>multiple inositol-polyphosphate phosphatase (myo-Inositol hexakisphosphate + H2O <=> 1L-myo-Inositol 1,2,3,4,6-pentakisphosphate + Orthophosphate)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O35217">O35217</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O35217">MINP1_RAT</A></td>
|
||
<td>similar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1QWO">1QWO</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QWO">Phosphoglycerate mutase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O35217">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O35217">Multiple inositol-polyphosphate phosphatase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9359836">9359836</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.1.3.72"><B>3.1.3.72</B></A></td>
|
||
<td>5-phytase; Systematic name: myo-inositol-hexakisphosphate 5-phosphohydrolase (myo-Inositol hexakisphosphate + H<sub>2</sub>O <=> 1L-myo-Inositol 1,2,3,4,6-pentakisphosphate + Orthophosphate)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q7WUJ1">Q7WUJ1</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q7WUJ1">Q7WUJ1_SELRU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1U24">1U24</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1U24">Phosphotyrosine protein phosphatases II</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q7WUJ1">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q7WUJ1">Pfam hit</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/17567745">17567745</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>218</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.93"><B>3.2.1.93</B></A></td>
|
||
<td>Alpha,-alpha-phosphotrehalase (H2O + alpha,alpha'-Trehalose 6-phosphate <=> D-Glucose + D-Glucose 6-phosphate)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P39795">P39795</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P39795">TREC_BACSU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1UOK">1UOK</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1UOK">TIM beta/alpha-barrel and Glycosyl hydrolase domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P39795">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P39795">Alpha amylase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/7751281">7751281</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.2.1.122"><B>3.2.1.122</B></A></td>
|
||
<td>Maltose-6'-phosphate glucosidase (H2O + alpha,alpha'-Trehalose 6-phosphate <=> D-Glucose + D-Glucose 6-phosphate)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O06901">O06901</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O06901">MALH_FUSMR</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1U8X">1U8X</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1U8X">LDH C-terminal domain-like and Rossmann-fold</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O06901">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O06901">Family 4 glycosyl hydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/11882720,7730284">11882720, 7730284</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>219</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.1.2"><B>3.5.1.2</B></A></td>
|
||
<td>Glutaminase (L-Glutamine + H<sub>2</sub>O <=> L-Glutamate + NH<sub>3</sub>)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9UI32">Q9UI32</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9UI32">GLSL_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3CZD">3CZD</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1U60">Beta-lactamase/ transpeptidase-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9UI32">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9UI32">Glutaminase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/18459799">18459799</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.5.1.38"><B>3.5.1.38</B></A></td>
|
||
<td>Glutamin-(asparagin-)ase (L-Glutamine + H<sub>2</sub>O <=> L-Glutamate + NH<sub>3</sub>)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q88K39">Q88K39</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q88K39">ASPQ_PSEPK</A>, <A href="http://www.uniprot.org/uniprot/P00805">ASPG2_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1DJO">1DJO</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1DJO">Glutaminase/ Asparaginase</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q88K39">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q88K39">Asparaginase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10684596,8434007,1521538">10684596, 8434007, 1521538</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>220</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.8.1.2"><B>3.8.1.2</B></A></td>
|
||
<td>(S)-2-haloacid dehalogenase ((S)-2-Haloacid + H<sub>2</sub>O <=> (R)-2-Hydroxyacid + Halide)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q52087">Q52087</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q52087">HADL_PSEPU</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1QH9">1QH9</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1QH9">HAD-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q52087">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q52087">Haloacid dehalogenase-like hydrolase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/1588303">1588303</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/3.8.1.10"><B>3.8.1.10</B></A></td>
|
||
<td>2-haloacid dehalogenase (configuration-inverting) ((S)-2-Haloacid + H<sub>2</sub>O <=> (R)-2-Hydroxyacid + Halide)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O06652">O06652</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O06652">HADDL_PSES4</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=3BJX">3BJX</A></td>
|
||
<td>-</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O06652">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O06652">Halocarboxylic acid dehydrogenase DehI</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9209038">9209038</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>221</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.4.2.2"><B>5.4.2.2</B></A></td>
|
||
<td>Phosphoglucomutase (Alpha-D-Ribose 1-phosphate <=> D-Ribose 5-phosphate)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P00949">P00949</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P00949">PGM1_RABIT</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1JDY">1JDY</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1JDY">Phosphoglucomutase first 3 domains and TBP-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P00949">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P00949">Phosphoglucomutase/ phosphomannomutase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15299905,1328221">15299905, 1328221</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/5.4.2.7"><B>5.4.2.7</B></A></td>
|
||
<td>Phosphopentomutase (Alpha-D-Ribose 1-phosphate <=> D-Ribose 5-phosphate)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P0A6K6">P0A6K6</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P0A6K6">DEOB_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2I09">2I09</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2I09">Alkaline phosphatase-like and DeoB insert domain-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P0A6K6">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P0A6K6">Phosphopentomutase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/4904508">4904508</A></td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>222</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.3.1.44"><B>1.3.1.44</B></A></td>
|
||
<td>Trans-2-enoyl-CoA reductase (NAD<sup>+</sup>) (Butanoyl-CoA + NAD<sup>+</sup> <=> Crotonoyl-CoA + NADH + H<sup>+</sup>)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q5EU90">Q5EU90</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q5EU90">TER_EUGGR</A></td>
|
||
<td>-</td>
|
||
<td>Predicted: Rossmann-fold</td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q5EU90">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q5EU90">Short-chain alcohol dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/15569691">15569691</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/1.3.99.2"><B>1.3.99.2</B></A></td>
|
||
<td>Butyryl-CoA dehydrogenase (Butanoyl-CoA + NAD<sup>+</sup> <=> Crotonoyl-CoA + NADH + H<sup>+</sup>)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q06319">Q06319</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q06319">ACDS_MEGEL</A>, <A href="http://www.uniprot.org/uniprot/P16219">ACADS_HUMAN</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1BUC">1BUC</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1BUC">Bromodomain-like and Acyl-CoA dehydrogenase NM domain-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q06319">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q06319">Acyl-CoA dehydrogenase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8399220,7857927">8399220, 7857927</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>223</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.5.1.44"><B>2.5.1.44</B></A></td>
|
||
<td>Homospermidine synthase (Putrescine + Spermidine <=> Homospermidine + 1,3-Diaminopropane)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/O32323">O32323</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/O32323">HSS_RHOVI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2PH5">2PH5</A></td>
|
||
<td>Predicted: <A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1E5Q">Rossman-fold and FwdE/GAPDH domain-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=O32323">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/O32323">Homospermidine synthase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/8841401">8841401</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.5.1.45"><B>2.5.1.45</B></A></td>
|
||
<td>Homospermidine synthase (spermidine-specific) (Putrescine + Spermidine <=> Homospermidine + 1,3-Diaminopropane)</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q9SC13">Q9SC13</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q9SC13">HSS1_SENVE</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1RLZ">1RLZ</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1RLZ">DHS-like NAD/FAD-binding domain</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q9SC13">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q9SC13">Deoxyhypusine synthase</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/10611289">10611289</A></td>
|
||
<td>Predicted analogs</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td center rowspan=2>224</td>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.1.31"><I>2.7.1.31</I></A></td>
|
||
<td>Glycerate 2-kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/P77364">P77364</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/P77364">GLXK1_ECOLI</A></td>
|
||
<td><A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1TO6">1TO6</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=1TO6">Glycerate kinase I</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=P77364">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/P77364">Glycerate kinase type-1</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/9772162">9772162</A></td>
|
||
<td rowspan=2>Two distinct structural folds</td>
|
||
</TR>
|
||
|
||
<TR>
|
||
<td><A href="http://enzyme.expasy.org/EC/2.7.1.31"><I>2.7.1.31</I></A></td>
|
||
<td>Glycerate 2-kinase</td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/protein/Q8IVS8">Q8IVS8</A></td>
|
||
<td><A href="http://www.uniprot.org/uniprot/Q8IVS8">GLCTK_HUMAN</A></td>
|
||
<td>smilar to <A href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2B8N">2B8N</A></td>
|
||
<td><A href="http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?ver=1.75&key=2B8N">GckA/TtuD-like</A></td>
|
||
<td><A href="http://www.supfam.org/SUPERFAMILY/cgi-bin/gene.cgi?genome=up;seqid=Q8IVS8">SupFam</A></td>
|
||
<td><A href="http://pfam.xfam.org/protein/Q8IVS8">Glycerate kinase type-2 (contains MOFRL domain)</A></td>
|
||
<td><A href="https://www.ncbi.nlm.nih.gov/pubmed/16753811,16865707">16753811, 16865707</A></td>
|
||
</TR>
|
||
|
||
</TBODY>
|
||
</TABLE> |