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<TITLE>Expired NOT-OD-23-040: Notice of Special Interest (NOSI): Advance Data Science Approaches Through Secondary Data Analysis to Reveal Scientific Insights of COVID-19 Testing Technologies (R21)</TITLE>
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<META NAME="description" CONTENT="NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Special Interest (NOSI): Advance Data Science Approaches Through Secondary Data Analysis to Reveal Scientific Insights of COVID-19 Testing Technologies (R21) NOT-OD-23-040. OD">
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<META NAME="Keywords" CONTENT="NOT-OD-23-040: Notice of Special Interest (NOSI): Advance Data Science Approaches Through Secondary Data Analysis to Reveal Scientific Insights of COVID-19 Testing Technologies (R21)">
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<link type="text/css" href="../guide_styles/css/expired.css" rel="stylesheet" media="all">
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<div class="noticeBar">This notice has expired. Check the <a href="https://grants.nih.gov/funding/searchguide/">NIH Guide</a> for active opportunities and notices.</div>
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<p id="watermark_text">EXPIRED</p>
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<span class="title">Notice of Special Interest (NOSI): Advance Data Science Approaches Through Secondary Data Analysis to Reveal Scientific Insights of COVID-19 Testing Technologies (R21)</span>
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<div class="heading4" tabindex="0" data-element-id="25861" data-element-required="true" data-element-has-value="true" data-section-code="OI" data-element-type="LINKED_ELEMENT">
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Notice Number:
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<div data-element-id="25861" data-element-has-label="true" data-element-required="true" data-element-has-value="true" data-section-code="OI" data-element-type="LINKED_ELEMENT">
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<span class="noticenum">NOT-OD-23-040</span>
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<a name="_Key_Dates"></a><h2 class="heading2">Key Dates</h2>
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Release Date:
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<p class="Normal">December 19, 2022</p>
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First Available Due Date:
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February 16, 2023
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Expiration Date:
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<strong> New Date </strong> January 5, 2024 as per <a href="https://grants.nih.gov/grants/guide/notice-files/NOT-OD-23-130.html">NOT-OD-23-130</a>
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<a name="_"></a><h2 class="heading2">Related Announcements</h2>
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<p class="Normal"><a href="https://grants.nih.gov/grants/guide/pa-files/PA-20-195.html">PA-20-195</a> - NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed)</p>
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<p class="Normal"><a href="https://grants.nih.gov/grants/guide/pa-files/PAR-20-150.html">PAR-20-150</a> - NIMHD Exploratory/Developmental Research Grant Program (R21 - Clinical Trial Optional)</p>
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<p class="Normal"><a href="https://grants.nih.gov/grants/guide/notice-files/NOT-OD-23-040.html">NOT-OD-23-040</a> - Notice of Special Interest (NOSI): Advance Data Science Approaches Through Secondary Data Analysis to Reveal Scientific Insights of COVID-19 Testing Technologies (R21)</p>
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</div>
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<div data-element-id="25868" data-element-has-label="false" data-element-required="true" data-element-has-value="true" data-section-code="OI" data-element-type="TEXT">
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<a name="_"></a><h2 class="heading2">Issued by</h2>
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<div data-element-id="25869" data-element-has-label="false" data-element-required="true" data-element-has-value="true" data-section-code="OI" data-element-type="LINKED_ELEMENT">
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<p>Office of Data Science Strategy (<a href="https://datascience.nih.gov/about/odss" target="_blank" rel="noreferrer">ODSS</a>)
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<p>National Institute on
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Aging (<a href="https://www.nia.nih.gov/" target="_blank" rel="noreferrer">NIA</a>)
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</p>
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<p>National Institute of Arthritis and Musculoskeletal and Skin Diseases (<a href="https://www.niams.nih.gov/" target="_blank" rel="noreferrer">NIAMS</a>)
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</p>
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<p>National Institute of Biomedical Imaging and Bioengineering (<a href="https://www.nibib.nih.gov/" target="_blank" rel="noreferrer">NIBIB</a>)
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</p>
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<p>Eunice Kennedy Shriver National Institute of Child Health and Human Development (<a href="https://www.nichd.nih.gov/" target="_blank" rel="noreferrer">NICHD</a>)
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</p>
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<p>National Institute of Dental and Craniofacial Research (<a href="https://www.nidcr.nih.gov/" target="_blank" rel="noreferrer">NIDCR</a>)
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</p>
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<p>National Institute on Drug Abuse (<a href="https://www.drugabuse.gov/" target="_blank" rel="noreferrer">NIDA</a>)
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</p>
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<p>National Institute of Mental Health (<a href="https://www.nimh.nih.gov/index.shtml" target="_blank" rel="noreferrer">NIMH</a>)
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</p>
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<p>National Institute on Minority Health and Health Disparities (<a href="https://www.nimhd.nih.gov/" target="_blank" rel="noreferrer">NIMHD</a>)
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</p>
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<p>National Library of Medicine (<a href="https://www.nlm.nih.gov/" target="_blank" rel="noreferrer">NLM</a>)
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</p>
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<p>All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers. The following NIH Offices may co-fund applications assigned to those Institutes/Centers.
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</p>
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<p>Office of Research on Women's Health (<a href="https://orwh.od.nih.gov/" target="_blank" rel="noreferrer">ORWH</a>)
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</p>
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</div>
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<a name="_"></a><h2 class="heading2">Purpose</h2>
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<p class="Normal">The purpose of this Notice of Special Interest (NOSI) is to support secondary data analysis to address questions and advance scientific inquiry related to SARS-CoV-2 through the existing data resources in the Rapid Acceleration of Dignostics Data Hub (<a href="https://radx-hub.nih.gov/">RADx DataHub</a>), including and in conjunction with other data resources.</p>
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<p class="Normal"><strong>Background</strong></p>
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<p class="Normal">The Rapid Acceleration of Diagnostics (RADx) Initiative is driving some of the nation’s most creative biomedical innovation by rapidly developing diverse COVID-19 testing technologies to national demands, with a focus on strategies for making testing broadly available, particularly to diverse, vulnerable, and underserved populations. The <a href="https://radx-hub.nih.gov/">RADx Data Hub</a>, (<a href="https://radx-hub.nih.gov/">https://radx-hub.nih.gov/</a>), is a centralized data repository for researchers to access datasets and analytic tools to the RADx program components: RADx-Tech and RADx Advanced Technology Platforms (<a href="https://www.nibib.nih.gov/covid-19/radx-tech-program">RADx Tech/ATP</a>), RADx Radical (<a href="https://www.radxrad.org/" Title="Link to Non-U.S. Government Site">RADx-rad</a>), RADx Underserved Populations (<a href="https://radx-up.org/" Title="Link to Non-U.S. Government Site">RADx-UP</a>), and Digital Health Solutions (<a href="https://www.nih.gov/news-events/news-releases/nih-awards-contracts-develop-innovative-digital-health-technologies-covid-19">DHS</a>). The RADx-Tech aims to speed the development, validation, and commercialization of innovative point-of-care and home-based tests, as well as improve clinical laboratory tests, that can directly detect virus. The RADx-ATP aims to advanced rapid scale-up technologies for achieving immediate, substantial increases in capacity. The RADx-rad targets innovative settings or non-traditional technologies to evaluate the usability, accessibility, robustness, or accuracy of the detection of COVID-19 infections. The RADx-UP aims to examine infection patterns and efforts for increasing access to and effectiveness of testing methods through engagement with diverse communities and populations. The DHS aims to facilitate approaches that leverage multiple data sources, privacy-preserving technologies, and computational tools for managing population health and individuals lives during the COVID-19 pandemic.</p>
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<p class="Normal"><strong>Research Objectives</strong></p>
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<p class="Normal">The research objective of this NOSI is to stimulate data science approaches by catalyzing the scientific value and revealing scientific insights through secondary analysis of existing data collected from the <a href="https://www.nih.gov/research-training/medical-research-initiatives/radx/radx-programs">RADx programs</a>. The research topic areas may include, but are not limited to, biomedical, clinical, social, ethical, and behavioral issues.</p>
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<p class="Normal">Examples of secondary analyses projects include, but are not limited to:</p>
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<ul>
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<li class="Normal">
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<p class="Normal">Validate public health measures</p>
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</li>
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<li class="Normal">
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<p class="Normal">Inform patient care</p>
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</li>
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<li class="Normal">
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<p class="Normal">Reduce health disparities for underserved and vulnerable populations</p>
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</li>
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<li class="Normal">
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<p class="Normal">Drive innovation in technologies offering more user-friendly designs</p>
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</li>
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<li class="Normal">
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<p class="Normal">Help stop and/or track the spread of COVID-19 virus or co-infectious materials</p>
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</li>
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<li class="Normal">
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<p class="Normal">Address better strategies to timely equip the biomedical workforce to test and identify future pathogens and other diseases</p>
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</ul>
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<div data-element-id="25872" data-element-has-label="false" data-element-required="true" data-element-has-value="true" data-section-code="OI" data-element-type="TEXT">
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<p class="Normal"><strong>Application and Submission Information</strong></p>
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<p class="Normal">Applicants must select the IC and associated FOA to use for submission of an application in response to the NOSI. The selection must align with the IC requirements listed in order to be considered responsive to that FOA. Non-responsive applications will be withdrawn from consideration for this initiative.</p>
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<p class="Normal">In addition, applicants using NIH Parent announcements (listed below) will be assigned to those ICs on this NOSI that have indicated those FOAs are acceptable and based on usual application-IC assignment practices.</p>
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<ul>
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<li class="Normal">
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<p class="Normal"><a href="https://grants.nih.gov/grants/guide/pa-files/PA-20-195.html" target="_blank">PA-20-195</a> - NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed)</p>
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</li>
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<li class="Normal"><a href="https://grants.nih.gov/grants/guide/pa-files/PAR-20-150.html">PAR-20-150</a> - NIMHD Exploratory/Developmental Research Grant Program (R21 - Clinical Trial Optional) for<strong> NIMHD</strong> applications only</span></span></li>
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</ul>
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<p class="Normal">All instructions in the <a href="https://grants.nih.gov/grants/how-to-apply-application-guide.html">SF424 (R&R) Application Guide</a> and the funding opportunity announcement used for submission must be followed, with the following additions:</p>
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<ul>
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<li class="Normal">
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<p class="Normal">For funding consideration, applicants must include NOT-OD-23-040 (without quotation marks) in the Agency Routing Identifier field (box 4B) of the SF424 R&R form. Applications without this information in box 4B will not be considered for this initiative.</p>
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</li>
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</ul>
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<div data-element-id="25873" data-element-has-label="false" data-element-required="false" data-element-has-value="false" data-section-code="OI" data-element-type="CUSTOM">
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</div>
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<div data-element-id="25874" data-element-has-label="false" data-element-required="true" data-element-has-value="true" data-section-code="OI" data-element-type="RADIO_BUTTON">
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<p class="Normal"><span style="background:white">Applications nonresponsive to terms of this NOSI will be withdrawn from consideration for this initiative.</span></p>
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<a name="_"></a><h2 class="heading2">Inquiries</h2>
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</div>
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<div data-element-id="25876" data-element-has-label="false" data-element-required="true" data-element-has-value="true" data-section-code="OI" data-element-type="RADIO_BUTTON">
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Please direct all inquiries to the contacts in Section VII of the listed funding opportunity announcements with the following additions/substitutions:
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</div>
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<div data-element-id="25877" data-element-has-label="false" data-element-required="false" data-element-has-value="true" data-section-code="OI" data-element-type="TEXT">
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<p class="Normal"><strong>Scientific/Research Contact(s)</strong></p>
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<p class="Normal">Partha Bhattacharyya, Ph.D.<br />
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National Institute on Aging (NIA)<br />
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Phone: (301) 496-3131<br />
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E-mail: <a href="/cdn-cgi/l/email-protection#ea88828b9e9e8b89828b9893938b9aaa878b8386c4848382c48d859c"><span class="__cf_email__" data-cfemail="5d3f353c29293c3e353c2f24243c2d1d303c343173333435733a322b">[email protected]</span></a></p>
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<p class="Normal">Jonathan W. King, Ph.D.<br />
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National Institute on Aging (NIA)<br />
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Phone: (301) 402-4156<br />
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E-mail: <a href="/cdn-cgi/l/email-protection#ee858780898481ae838f8782c0808786c0898198"><span class="__cf_email__" data-cfemail="83e8eaede4e9ecc3eee2eaefadedeaebade4ecf5">[email protected]</span></a></p>
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<p class="Normal">Marie Mancini, Ph.D.<br />
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National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)<br />
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Telephone: 301-594-5032<br />
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Email: <a href="/cdn-cgi/l/email-protection#583539363b313631356a183539313476363130763f372e"><span class="__cf_email__" data-cfemail="167b7778757f787f7b24567b777f7a38787f7e38717960">[email protected]</span></a></p>
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<p class="Normal">Andrew Weitz, Ph.D.<br />
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National Institute of Biomedical Imaging and Bioengineering (NIBIB)<br />
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Phone: (301) 451-7813<br />
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E-mail: <a href="/cdn-cgi/l/email-protection#aecfc0cadccbd980d9cbc7dad4eec0c7c680c9c1d8"><span class="__cf_email__" data-cfemail="debfb0baacbba9f0a9bbb7aaa49eb0b7b6f0b9b1a8">[email protected]</span></a></p>
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<p class="Normal">Rebecca F. Rosen, Ph.D.<br />
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Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)<br />
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Email: <a href="/cdn-cgi/l/email-protection#32405750575151531c405d41575c725c5b5a1c555d44"><span class="__cf_email__" data-cfemail="f785929592949496d98598849299b7999e9fd9909881">[email protected]</span></a></p>
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<p class="Normal">Noffisat Oki, Ph.D.<br />
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National Institute of Dental & Craniofacial Research (NIDCR)<br />
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Phone: 301-402-6778<br />
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E-mail: <a href="/cdn-cgi/l/email-protection#214f4e4747485240550f4e4a48614f48490f464e57"><span class="__cf_email__" data-cfemail="137d7c75757a6072673d7c787a537d7a7b3d747c65">[email protected]</span></a></p>
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<p class="Normal">Susan Nicole Wright, Ph.D.<br />
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National Institute on Drug Abuse (NIDA)<br />
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Phone: 301-402-6683<br />
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E-mail: <a href="/cdn-cgi/l/email-protection#21525452404f0f565348464955614f48490f464e57"><span class="__cf_email__" data-cfemail="ea999f998b84c49d98838d829eaa848382c48d859c">[email protected]</span></a></p>
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<p class="Normal">Lori A.J. Scott-Sheldon, Ph.D.<br />
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National Institute of Mental Health (NIMH)<br />
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Telephone: 301-792-2309<br />
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E-mail: <a href="/cdn-cgi/l/email-protection#90fcffe2f9bee3f3ffe4e4bde3f8f5fcf4fffed0fef9f8bef7ffe6"><span class="__cf_email__" data-cfemail="f5999a879cdb86969a8181d8869d9099919a9bb59b9c9ddb929a83">[email protected]</span></a></p>
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<p class="Normal">Nancy L. Jones, Ph.D.<br />
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National Institute on Minority Health and Health Disparities (NIMHD)<br />
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Phone: 301-594-8945<br />
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E-mail: <a href="/cdn-cgi/l/email-protection#2a444b444953044045444f596a444342044d455c"><span class="__cf_email__" data-cfemail="84eae5eae7fdaaeeebeae1f7c4eaedecaae3ebf2">[email protected]</span></a></p>
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<p class="Normal">Yanli Wang, Ph.D.<br />
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National Library of Medicine (NLM)<br />
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Phone: 301-827-7092<br />
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E-mail: <a href="/cdn-cgi/l/email-protection#4b322a252722653c2a252c0b252223652c243d"><span class="__cf_email__" data-cfemail="255c444b494c0b52444b42654b4c4d0b424a53">[email protected]</span></a></p>
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<p class="Normal">Ching-Yi Shieh, Ph.D.<br />
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Office of Research on Women's Health (ORWH)<br />
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Phone:301-496-9186<br />
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Office of Data Science Strategy (ODSS)<br />
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E-mail: <a href="/cdn-cgi/l/email-protection#412d3422386f293234012f28296f262e37"><u><span class="__cf_email__" data-cfemail="a4c8d1c7dd8accd7d1e4cacdcc8ac3cbd2">[email protected]</span></u></a><a href="/cdn-cgi/l/email-protection#3e5c565f4a4a5f5d565f4c47475f4e7e535f57521050575610595148"></a></p>
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