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4413 lines
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221 KiB
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<title>Safety and efficacy of once-daily risdiplam in type 2 and non-ambulant type 3 spinal muscular atrophy (SUNFISH part 2): a phase 3, double-blind, randomised, placebo-controlled trial - PubMed</title>
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is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Dorina', lastname='Seger', initials='D', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Sibylle', lastname='Vogt', initials='S', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Enrico', lastname='Bertini', initials='E', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Adele', lastname="D'Amico", initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Sergio', lastname='Petroni', initials='S', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Anna Maria', lastname='Bonetti', initials='AM', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Adelina', lastname='Carlesi', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Irene', lastname='Mizzoni', initials='I', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Claudio', lastname='Bruno', initials='C', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Enrico', lastname='Priolo', initials='E', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Giuseppe', lastname='Rao', initials='G', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Simone', lastname='Morando', initials='S', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Paola', lastname='Tacchetti', initials='P', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Ambra', lastname='Zuffi', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Giacomo Pietro', lastname='Comi', initials='GP', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Roberta', lastname='Brusa', initials='R', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Stefania', lastname='Corti', initials='S', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Velardo', lastname='Daniele', initials='V', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Alessandra', lastname='Govoni', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Francesca', lastname='Magri', initials='F', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Valeria', lastname='Minorini', initials='V', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Silvia Gabriella', lastname='Osnaghi', initials='SG', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Francesca', lastname='Abbati', initials='F', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Federica', lastname='Fassini', initials='F', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Michaela', lastname='Foa', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Amaqlia', lastname='Lopopolo', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Megi', lastname='Meneri', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Francesca', lastname='Zoppas', initials='F', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Valeria', lastname='Parente', initials='V', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Giovanni', lastname='Baranello', initials='G', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Riccardo', lastname='Masson', initials='R', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Stefania', lastname='Bianchi Marzoli', initials='S', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Diletta', lastname='Santarsiero', initials='D', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Myriam', lastname='Garcia Sierra', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Gemma', lastname='Tremolada', initials='G', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Maria Teresa', lastname='Arnoldi', initials='MT', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Marta', lastname='Vigano', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Riccardo', lastname='Zanin', initials='R', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Eugenio', lastname='Mercuri', initials='E', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Giulia Maria', lastname='Amorelli', initials='GM', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Costanza', lastname='Barresi', initials='C', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Gugliemo', lastname="D'Amico", initials='G', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Lorenzo', lastname='Orazi', initials='L', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Giorgia', lastname='Coratti', initials='G', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Kazuhiro', lastname='Haginoya', initials='K', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Atsuko', lastname='Kato', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Yuko', lastname='Morishita', initials='Y', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Ryutaro', lastname='Kira', initials='R', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Kiyomu', lastname='Akiyama', initials='K', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Miwako', lastname='Goto', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Yujiro', lastname='Mori', initials='Y', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Misato', lastname='Okamoto', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Saki', lastname='Tsutsui', initials='S', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Yuta', lastname='Takatsuji', initials='Y', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Aya', lastname='Tanaka', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Hirofumi', lastname='Komaki', initials='H', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Ippei', lastname='Suzuki', initials='I', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Mizuki', lastname='Takeuchi', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Daisuke', lastname='Todoroki', initials='D', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Seji', lastname='Watanabe', initials='S', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Miina', lastname='Omori', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Tomoko', lastname='Matsubayashi', initials='T', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Emi', lastname='Inakazu', initials='E', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Hiroe', lastname='Nagura', initials='H', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Akira', lastname='Suzuki', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Hitoshi', lastname='Osaka', initials='H', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Manami', lastname='Ohashi', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Nobutsune', lastname='Ishikawa', initials='N', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Yousuke', lastname='Harada', initials='Y', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Kenichi', lastname='Fudeyasu', initials='K', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Kazuhiko', lastname='Hirata', initials='K', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Kana', lastname='Michiue', initials='K', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Kazuyuki', lastname='Ueda', initials='K', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Kayoko', lastname='Saito', initials='K', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Shigeko', lastname='Yashiro', initials='S', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Maiko', lastname='Seki', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Nozomi', lastname='Sano', initials='N', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Akinori', lastname='Uemura', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Koji', lastname='Fukuyama', initials='K', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Yuki', lastname='Matsumoto', initials='Y', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Hirofumi', lastname='Miyazaki', initials='H', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Minoru', lastname='Shibata', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Kyoko', lastname='Kobayashi', initials='K', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Yukie', lastname='Nakamura', initials='Y', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Yasuhiro', lastname='Takeshima', initials='Y', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Moe', lastname='Kuma', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Anna', lastname='Kostera-Pruszczyk', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Anna', lastname='Fraczek', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Maria', lastname='Jedrzejowska', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Anna', lastname='Lusakowska', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Agnieszka', lastname='Czeszyk-Piotrowicz', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Wojciech', lastname='Hautz', initials='W', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Klaudia', lastname='Rakusiewicz', initials='K', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Malgorzata', lastname='Burlewicz', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Zuzanna', lastname='Gierlak-Wojcicka', initials='Z', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Malwina', lastname='Kepa', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Adam', lastname='Sikorski', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Marcin', lastname='Sobieraj', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Maria', lastname='Mazurkiewicz-Beldzinska', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Anna', lastname='Lemska', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Sandra', lastname='Modrzejewska', initials='S', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Mateusz', lastname='Koberda', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Urszula', lastname='Stodolska-Koberda', initials='U', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Agnieszka', lastname='Waskowska', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Jagoda', lastname='Kolendo', initials='J', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Agnieszka', lastname='Sobierajska-Rek', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Barbara', lastname='Steinborn', initials='B', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Magdalena', lastname='Dalz', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Julia', lastname='Grabowska', initials='J', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Wojciech', lastname='Hajduk', initials='W', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Justyna', lastname='Janasiewicz-Karachitos', initials='J', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Monika', lastname='Klimas', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Marcin', lastname='Stopa', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Ewa', lastname='Gajewska', initials='E', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Beata', lastname='Pusz', initials='B', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Dmitry', lastname='Vlodavets', initials='D', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Evgenia', lastname='Melnik', initials='E', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Natalya', lastname='Leppenen', initials='N', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Nataliya', lastname='Yupatova', initials='N', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Anastasya', lastname='Monakhova', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Yulia', lastname='Papina', initials='Y', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Olga', lastname='Shidlovsckaia', initials='O', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Vedrana', lastname='Milic Rasic', initials='V', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Vesna', lastname='Brankovic', initials='V', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Ana', lastname='Kosac', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Olivera', lastname='Djokic', initials='O', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Vesna', lastname='Jakšić', initials='V', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Ana', lastname='Pepic', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Jelena', lastname='Martinovic', initials='J', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Francina', lastname='Munell Casadesus', initials='F', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Eduardo', lastname='Tizzano', initials='E', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Nieves', lastname='Martín Begué', initials='N', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Charlotte', lastname='Wolley Dod', initials='C', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Olaia', lastname='Subira', initials='O', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Bernat', lastname='Planas Pascual', initials='B', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Esther', lastname='Toro Tamargo', initials='E', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Marcos', lastname='Madruga Garrido', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='José David', lastname='Medina Romero', initials='JD', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Marta Peña', lastname='Salinas', initials='MP', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Andrés', lastname='Nascimento Osorio', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Ana', lastname='Díaz Cortés', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Enrique', lastname='Jiménez Gañan', initials='E', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Simone Dowon', lastname='Suh', initials='SD', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Julita', lastname='Medina Cantillo', initials='J', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Obdulia', lastname='Moya', initials='O', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Nuria', lastname='Padros', initials='N', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Sandra', lastname='Roca Urraca', initials='S', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Hugo', lastname='Gonzalez Valdivia', initials='H', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Samuel', lastname='Pascual Pascual', initials='S', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Sofía', lastname='de Manuel', initials='S', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Susana', lastname='Noval Martin', initials='S', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Paul', lastname='Burnham', initials='P', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Sandra', lastname='Espinosa Garcia', initials='S', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Mercedes', lastname='Martinez Moreno', initials='M', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Haluk', lastname='Topaloglu', initials='H', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Ibrahim', lastname='Oncel', initials='I', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Nesibe', lastname='Eroglu Ertugrul', initials='N', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Bahadir', lastname='Konuskan', initials='B', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Bora', lastname='Eldem', initials='B', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Sibel', lastname='Kadayifçilar', initials='S', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Ipek', lastname='Alemdaroglu', initials='I', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Aynur', lastname='Ayse Karaduman', initials='A', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Oznur', lastname='Tunca Yilmaz', initials='O', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Neslihan', lastname='Bilgin', initials='N', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Seher', lastname='Sari', initials='S', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Claudia', lastname='Chiriboga', initials='C', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Steven', lastname='Kane', initials='S', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='John', lastname='Lee', initials='J', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Donnielle', lastname='Rome-Martin', initials='D', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='John W', lastname='Day', initials='JW', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Shannon', lastname='Beres', initials='S', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Tina', lastname='Duong', initials='T', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Richard', lastname='Gee', initials='R', affs=[], is_editor=False, suffix=None, equal_contrib=False), Author(firstnames='Sally', lastname='Dunaway Young', initials='S', affs=[], is_editor=False, suffix=None, equal_contrib=False)], affs=[]), Adolescent, Adult, Aged, Azo Compounds / adverse effects, Child, Child, Preschool, Double-Blind 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|
||
<input type="hidden" name="csrfmiddlewaretoken" value="Ff6FWHvGyDWYw5sPbaxhVURPbDv4sFpjW2QKzxY28eJsqwyFOtajp2ntJHdglgXD">
|
||
|
||
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="save-action-format" class="action-panel-label">
|
||
Format:
|
||
</label>
|
||
<select id="save-action-format" name="results-format" class="action-panel-selector">
|
||
<option value="summary-text">Summary (text)</option>
|
||
<option value="pubmed-text">PubMed</option>
|
||
<option value="pmid">PMID</option>
|
||
<option value="abstract">Abstract (text)</option>
|
||
<option value="csv">CSV</option>
|
||
</select>
|
||
</div>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Saving..."
|
||
data-ga-category="save_share"
|
||
data-ga-action="save"
|
||
data-ga-label="save">
|
||
Create file
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Save citations to file' panel"
|
||
ref="linksrc=close_save_panel"
|
||
aria-controls="save-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="save"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div id="email-action-panel"
|
||
class="email-action-panel action-panel"
|
||
aria-hidden="true"
|
||
data-recaptcha-script-url="https://www.recaptcha.net/recaptcha/enterprise.js?render=explicit&onload=onloadCaptchaCallback"
|
||
data-recaptcha-enabled="true">
|
||
<div class="inner-wrap">
|
||
<h2 class="action-panel-heading">
|
||
Email citation
|
||
</h2>
|
||
<form id="email-action-panel-form"
|
||
class="action-panel-content action-form"
|
||
action="/send-email/"
|
||
data-by-search-action="/results-export-email-by-search-data/"
|
||
data-by-ids-action="/send-email/"
|
||
data-by-search-method="post"
|
||
data-by-ids-method="post"
|
||
method="post"
|
||
>
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="Ff6FWHvGyDWYw5sPbaxhVURPbDv4sFpjW2QKzxY28eJsqwyFOtajp2ntJHdglgXD">
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<span class="action-panel-label">
|
||
Subject:
|
||
</span>
|
||
<span class="email-subject" id="email-subject" aria-label="Email subject">1 selected item: 34942136 - PubMed</span>
|
||
<input type="hidden" name="email-subject" value="1 selected item: 34942136"/>
|
||
<input type="hidden" name="email-subject-hash" value="a1f61a9346d95925b0ccfd5fca6215b6f1321cdcb73a9729cb90222a6f249736"/>
|
||
</div>
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="email-to" class="action-panel-label required-field-asterisk">
|
||
To:
|
||
</label>
|
||
<input type="email" aria-label="Recipient Email Address" placeholder="email@example.com" id="email-to" class="email-to" pattern="^[a-zA-Z0-9_.+-]+@[a-zA-Z0-9-]+\.[a-zA-Z0-9-.]+$" maxlength="100" required>
|
||
</div>
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="email-from" class="action-panel-label">
|
||
From:
|
||
</label>
|
||
<input type="email" aria-label="Sender Email Address" placeholder="email@example.com" id="email-from" class="email-from" pattern="^[a-zA-Z0-9_.+-]+@[a-zA-Z0-9-]+\.[a-zA-Z0-9-.]+$" maxlength="256">
|
||
</div>
|
||
|
||
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="email-citation-format" class="action-panel-label">
|
||
Format:
|
||
</label>
|
||
<select id="email-citation-format" name="citation-format" class="action-panel-selector email-citation-format">
|
||
<option selected="selected" value="summary">Summary</option>
|
||
<option value="summary-text">Summary (text)</option>
|
||
<option value="abstract">Abstract</option>
|
||
<option value="abstract-text">Abstract (text)</option>
|
||
|
||
</select>
|
||
</div>
|
||
<div class="include-supplemental-container">
|
||
<input type="checkbox" aria-label="Include MeSH and other data" name="include-supplemental" id="email-include-supplemental" class="email-include-supplemental">
|
||
<label for="email-include-supplemental" class="email-include-supplemental-label">MeSH and other data</label>
|
||
</div>
|
||
|
||
|
||
|
||
<div class="form-field recaptcha ">
|
||
|
||
|
||
|
||
<div class="g-recaptcha" id="id-recaptcha" data-sitekey="6LfsWHMdAAAAAClKbtOpjQ2pMjgsGxvv7NdZW9uI"></div>
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
<div id="captcha-error-message" class="usa-input-error-message captcha-validation-message" role="alert"></div>
|
||
|
||
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Sending..."
|
||
data-ga-category="save_share"
|
||
data-ga-action="email"
|
||
data-ga-label="send">
|
||
Send email
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Email citations' panel"
|
||
ref="linksrc=close_email_panel"
|
||
aria-controls="email-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="email"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
<input type="hidden" name="email-search-details" value="" />
|
||
<input type="hidden" name="email-search-details-hash" value="0e42663a6c3bd85498fcb88798998fed7bfdc45d457db35281e41afe13cc0524" />
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="collections-action-panel"
|
||
class="collections-action-panel action-panel in-progress-dots-panel"
|
||
aria-hidden="true"
|
||
data-collections-open-panel-enabled="false"
|
||
data-collections-open-panel-url-hash="#open-collections-panel">
|
||
<div class="inner-wrap">
|
||
<h3 class="action-panel-heading">
|
||
Add to Collections
|
||
</h3>
|
||
|
||
|
||
<form id="collections-action-panel-form"
|
||
class="collections-action-panel-form action-panel-content action-form action-panel-smaller-selectors"
|
||
data-existing-collections-url="/list-existing-collections/"
|
||
data-add-to-existing-collection-url="/add-to-existing-collection/"
|
||
data-create-and-add-to-new-collection-url="/create-and-add-to-new-collection/"
|
||
data-get-article-ids-by-search-url="/get-article-ids-by-search/"
|
||
data-myncbi-max-collection-name-length="100"
|
||
data-add-to-collection-max-amount="1000"
|
||
data-collections-root-url="https://www.ncbi.nlm.nih.gov/myncbi/collections/">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="Ff6FWHvGyDWYw5sPbaxhVURPbDv4sFpjW2QKzxY28eJsqwyFOtajp2ntJHdglgXD">
|
||
|
||
|
||
|
||
<div class="choice-group" role="radiogroup">
|
||
<ul class="radio-group-items">
|
||
<li>
|
||
<input type="radio"
|
||
id="collections-action-panel-new"
|
||
class="collections-new"
|
||
name="collections"
|
||
value="new"
|
||
data-ga-category="save_share"
|
||
data-ga-action="collections"
|
||
data-ga-label="collections_radio_new">
|
||
<label for="collections-action-panel-new">Create a new collection</label>
|
||
</li>
|
||
<li>
|
||
<input type="radio"
|
||
id="collections-action-panel-existing"
|
||
class="collections-existing"
|
||
name="collections"
|
||
value="existing"
|
||
checked="true"
|
||
data-ga-category="save_share"
|
||
data-ga-action="collections"
|
||
data-ga-label="collections_radio_existing">
|
||
<label for="collections-action-panel-existing">Add to an existing collection</label>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
|
||
<div class="controls-wrapper">
|
||
<div class="action-panel-control-wrap new-collections-controls">
|
||
<label for="collections-action-panel-add-to-new" class="action-panel-label required-field-asterisk">
|
||
Name your collection:
|
||
</label>
|
||
<input
|
||
type="text"
|
||
name="add-to-new-collection"
|
||
id="collections-action-panel-add-to-new"
|
||
class="collections-action-add-to-new"
|
||
pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/"
|
||
maxlength="100"
|
||
data-ga-category="save_share"
|
||
data-ga-action="create_collection"
|
||
data-ga-label="non_favorties_collection">
|
||
<div class="collections-new-name-too-long usa-input-error-message selection-validation-message">
|
||
Name must be less than 100 characters
|
||
</div>
|
||
</div>
|
||
<div class="action-panel-control-wrap existing-collections-controls">
|
||
<label for="collections-action-panel-add-to-existing" class="action-panel-label">
|
||
Choose a collection:
|
||
</label>
|
||
<select id="collections-action-panel-add-to-existing"
|
||
class="action-panel-selector collections-action-add-to-existing"
|
||
data-ga-category="save_share"
|
||
data-ga-action="select_collection"
|
||
data-ga-label="($('#collections-action-add-to-existing').val() === 'Favorites') ? 'Favorites' : 'non_favorites_collection'">
|
||
</select>
|
||
<div class="collections-retry-load-on-error usa-input-error-message selection-validation-message">
|
||
Unable to load your collection due to an error<br>
|
||
<a href="#">Please try again</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Adding..."
|
||
data-pinger-ignore
|
||
data-ga-category="save_share"
|
||
data-ga-action="collections"
|
||
data-ga-label="add">
|
||
Add
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Add to Collections' panel"
|
||
ref="linksrc=close_collections_panel"
|
||
aria-controls="collections-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="collections"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="bibliography-action-panel"
|
||
class="bibliography-action-panel action-panel in-progress-dots-panel"
|
||
aria-hidden="true"
|
||
data-bibliography-open-panel-enabled="false"
|
||
data-bibliography-open-panel-url-hash="#open-bibliography-panel">
|
||
<div class="inner-wrap">
|
||
<h3 class="action-panel-heading">
|
||
Add to My Bibliography
|
||
</h3>
|
||
<form id="bibliography-action-panel-form"
|
||
class="bibliography-action-panel-form action-panel-content action-form action-panel-smaller-selectors"
|
||
data-add-to-bibliography-max-amount="100"
|
||
data-add-to-bibliography-batch-size="10"
|
||
data-bibliography-delegates-url="/list-bibliography-delegates/"
|
||
data-add-to-bibliography-url="/add-to-bibliography/"
|
||
data-get-article-ids-by-search-url="/get-article-ids-by-search/"
|
||
data-mybib-root-url="https://www.ncbi.nlm.nih.gov/myncbi/collections/mybibliography/">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="Ff6FWHvGyDWYw5sPbaxhVURPbDv4sFpjW2QKzxY28eJsqwyFOtajp2ntJHdglgXD">
|
||
|
||
|
||
|
||
<div class="action-panel-control-wrap bibliographies-controls">
|
||
<div class="choice-group">
|
||
<ul class="bibliographies-action-add radio-group-items">
|
||
<li>
|
||
<input name="bibliography" id="my-bibliography" class="my-bibliography" type="radio" checked/>
|
||
<label for="my-bibliography">My Bibliography</label>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="bibliographies-retry-load-on-error usa-input-error-message selection-validation-message">
|
||
Unable to load your delegates due to an error<br>
|
||
<a href="#">Please try again</a>
|
||
</div>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Adding..."
|
||
data-pinger-ignore>
|
||
Add
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Add to bibliography' panel"
|
||
ref="linksrc=close_bibliography_panel"
|
||
aria-controls="bibliography-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="mybib"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div id="saved-search-action-panel" class="saved-search-action-panel action-panel " aria-hidden="true"
|
||
data-saved-search-open-panel-enabled="false"
|
||
data-saved-search-open-panel-url-hash="#open-saved-search-panel">
|
||
<div class="inner-wrap">
|
||
<h2 class="action-panel-heading">
|
||
Your saved search
|
||
</h2>
|
||
|
||
<form id="saved-search-action-panel-form"
|
||
class="saved-search-action-panel-form action-panel-content action-form"
|
||
data-create-saved-search-url="/create-saved-search/"
|
||
data-try-search-terms-url="/try-search-term/"
|
||
data-saved-search-root-url="https://www.ncbi.nlm.nih.gov/myncbi/searches/">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="Ff6FWHvGyDWYw5sPbaxhVURPbDv4sFpjW2QKzxY28eJsqwyFOtajp2ntJHdglgXD">
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="saved-search-name" class="action-panel-label saved-search-name-label required-field-asterisk">
|
||
Name of saved search:
|
||
</label>
|
||
<input maxlength="200"
|
||
type="text"
|
||
name="saved-search-name"
|
||
id="saved-search-name"
|
||
class="saved-search-name"
|
||
value=""
|
||
required
|
||
pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/">
|
||
</div>
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="saved-search-term" class="action-panel-label required-field-asterisk">
|
||
Search terms:
|
||
</label>
|
||
<textarea name="saved-search-term" id="saved-search-term" class="saved-search-term" required></textarea>
|
||
</div>
|
||
<div class="test-search-term-wrap">
|
||
<a href="#" class="try-search-term">Test search terms</a>
|
||
</div>
|
||
<div class="choice-group action-panel-extra-margin-top">
|
||
<span class="action-panel-label" id="fieldset-label">
|
||
Would you like email updates of new search results?
|
||
</span>
|
||
<fieldset id="saved-search-alert" aria-describedby="fieldset-label">
|
||
<legend class="usa-sr-only">Saved Search Alert Radio Buttons</legend>
|
||
<ul class="radio-group-items">
|
||
<li>
|
||
<input type="radio" id="saved-search-alert-yes" class="saved-search-alert-yes" name="saved-search-alert" value="yes" checked>
|
||
<label for="saved-search-alert-yes" class="action-panel-label">Yes</label>
|
||
</li>
|
||
<li>
|
||
<input aria-label="No radio input" type="radio" id="saved-search-alert-no" class="saved-search-alert-no" name="saved-search-alert" value="no">
|
||
<label for="saved-search-alert-no" class="action-panel-label">No</label>
|
||
</li>
|
||
</ul>
|
||
</fieldset>
|
||
</div>
|
||
|
||
<div class="alert-schedule-wrap">
|
||
<div class="action-panel-control-wrap">
|
||
<label class="action-panel-label">
|
||
Email:
|
||
</label>
|
||
<span aria-label="Email address" id="saved-search-email" class="action-panel-label"><span class="action-panel-label-bold"></span> (<a class="myncbi-account-settings" href="https://www.ncbi.nlm.nih.gov/account/settings/">change</a>)</span>
|
||
</div>
|
||
<div class="action-panel-control-wrap action-panel-extra-margin-top">
|
||
<label for="saved-search-frequency" class="action-panel-label">
|
||
Frequency:
|
||
</label>
|
||
<select id="saved-search-frequency" class="no-border-panel-selector saved-search-frequency">
|
||
<option value="monthly">Monthly</option>
|
||
<option value="weekly">Weekly</option>
|
||
<option value="daily">Daily</option>
|
||
</select>
|
||
</div>
|
||
<div class="action-panel-control-wrap saved-search-monthly-additional">
|
||
<label for="saved-search-monthly-on-day" class="action-panel-label">
|
||
Which day?
|
||
</label>
|
||
<select id="saved-search-monthly-on-day" class="no-border-panel-selector">
|
||
<option value="Sunday">The first Sunday</option>
|
||
<option value="Monday">The first Monday</option>
|
||
<option value="Tuesday">The first Tuesday</option>
|
||
<option value="Wednesday">The first Wednesday</option>
|
||
<option value="Thursday">The first Thursday</option>
|
||
<option value="Friday">The first Friday</option>
|
||
<option value="Saturday">The first Saturday</option>
|
||
<option value="day">The first day</option>
|
||
<option value="weekday">The first weekday</option>
|
||
</select>
|
||
</div>
|
||
<div class="action-panel-control-wrap saved-search-weekly-additional">
|
||
<label for="saved-search-weekly-on-day" class="action-panel-label">
|
||
Which day?
|
||
</label>
|
||
<select id="saved-search-weekly-on-day" class="no-border-panel-selector saved-search-weekly-on-day">
|
||
<option value="Sunday">Sunday</option>
|
||
<option value="Monday">Monday</option>
|
||
<option value="Tuesday">Tuesday</option>
|
||
<option value="Wednesday">Wednesday</option>
|
||
<option value="Thursday">Thursday</option>
|
||
<option value="Friday">Friday</option>
|
||
<option value="Saturday">Saturday</option>
|
||
</select>
|
||
</div>
|
||
<div class="action-panel-control-wrap">
|
||
<label for="saved-search-report" class="action-panel-label">
|
||
Report format:
|
||
</label>
|
||
<select id="saved-search-report" class="no-border-panel-selector saved-search-report">
|
||
<option value="DocSum">Summary</option>
|
||
<option value="DocSumText">Summary (text)</option>
|
||
<option value="Abstract">Abstract</option>
|
||
<option value="AbstractText">Abstract (text)</option>
|
||
<option value="MEDLINE">PubMed</option>
|
||
</select>
|
||
</div>
|
||
<div class="action-panel-control-wrap">
|
||
<label for="saved-search-amount" class="action-panel-label">
|
||
Send at most:
|
||
</label>
|
||
<select id="saved-search-amount" class="no-border-panel-selector saved-search-amount">
|
||
<option value="1">1 item</option>
|
||
<option value="5" selected>5 items</option>
|
||
<option value="10">10 items</option>
|
||
<option value="20">20 items</option>
|
||
<option value="50">50 items</option>
|
||
<option value="100">100 items</option>
|
||
<option value="200">200 items</option>
|
||
</select>
|
||
</div>
|
||
<div>
|
||
<input type="checkbox" id="saved-search-send-if-no-result" class="saved-search-send-if-no-result" name="saved-search-send-if-no-result">
|
||
<label for="saved-search-send-if-no-result" class="action-panel-label smaller-checkbox">
|
||
Send even when there aren't any new results
|
||
</label>
|
||
</div>
|
||
<div class="action-panel-control-wrap option-text-in-email-wrap">
|
||
<label for="saved-search-email-text" class="action-panel-label">
|
||
Optional text in email:
|
||
</label>
|
||
<textarea name="saved-search-email-text"
|
||
id="saved-search-email-text"
|
||
class="saved-search-email-text"></textarea>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Saving..."
|
||
data-ga-category="save_share"
|
||
data-ga-action="alert"
|
||
data-ga-label="save">
|
||
Save
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Your saved search' panel"
|
||
ref="linksrc=close_saved_search_panel"
|
||
aria-controls="saved-search-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="alert"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="citation-manager-action-panel" class="citation-manager-action-panel action-panel" aria-hidden="true">
|
||
<div class="inner-wrap">
|
||
<h2 class="action-panel-heading">
|
||
Create a file for external citation management software
|
||
</h2>
|
||
<form id="citation-manager-action-panel-form"
|
||
class="action-panel-content action-form"
|
||
action="/results-export-ids/"
|
||
data-by-search-action="/results-export-search-data/"
|
||
data-by-ids-action="/results-export-ids/"
|
||
method="post"
|
||
data-by-search-method="post"
|
||
data-by-ids-method="post">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="Ff6FWHvGyDWYw5sPbaxhVURPbDv4sFpjW2QKzxY28eJsqwyFOtajp2ntJHdglgXD">
|
||
|
||
|
||
|
||
<input name="results-format" type="hidden" value="pubmed"/>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Sending..."
|
||
data-ga-category="save_share"
|
||
data-ga-action="citation_manager"
|
||
data-ga-label="save">
|
||
Create file
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Send citations to citation manager' panel"
|
||
ref="linksrc=close_citation_manager_panel"
|
||
aria-controls="citation-manager-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="citation_manager"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div id="rss-action-panel" class="rss-action-panel action-panel " aria-hidden="true">
|
||
<div class="inner-wrap">
|
||
<h2 class="action-panel-heading">
|
||
Your RSS Feed
|
||
</h2>
|
||
|
||
<form id="rss-action-panel-form"
|
||
class="rss-action-panel-form action-panel-content action-form"
|
||
data-create-rss-feed-url="/create-rss-feed-url/"
|
||
data-search-form-term-value="">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="Ff6FWHvGyDWYw5sPbaxhVURPbDv4sFpjW2QKzxY28eJsqwyFOtajp2ntJHdglgXD">
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="rss-name" class="action-panel-label required-field-asterisk">
|
||
Name of RSS Feed:
|
||
</label>
|
||
<input maxlength="200"
|
||
placeholder="Name"
|
||
type="text"
|
||
name="rss-name"
|
||
id="rss-name"
|
||
class="rss-name"
|
||
value=''
|
||
required
|
||
pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/">
|
||
</div>
|
||
|
||
<div class="rss-limit-wrap">
|
||
<div class="action-panel-control-wrap action-panel-extra-margin-top">
|
||
<label for="rss-limit" class="action-panel-label">
|
||
Number of items displayed:
|
||
</label>
|
||
<select id="rss-limit" class="no-border-panel-selector rss-limit">
|
||
<option value="5">5</option>
|
||
<option value="10">10</option>
|
||
<option value="15" selected="selected">15</option>
|
||
<option value="20">20</option>
|
||
<option value="50">50</option>
|
||
<option value="100">100</option>
|
||
</select>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Creating..."
|
||
data-ga-category="save_share"
|
||
data-ga-action="alert"
|
||
data-ga-label="save">
|
||
Create RSS
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Your RSS' panel"
|
||
ref="linksrc=close_rss_panel"
|
||
aria-controls="rss-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="alert"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
|
||
<div class="action-panel-control-wrap rss-link-copy-wrap">
|
||
<label for="rss-link" class="usa-sr-only">RSS Link</label>
|
||
<input placeholder="Your RSS Feed Link" type="text" name="rss-link" id="rss-link" class="rss-link" title="RSS Link">
|
||
<button
|
||
type="button"
|
||
disabled
|
||
class="rss-link-copy-button disabled"
|
||
data-ga-category="save_share"
|
||
data-ga-action="rss"
|
||
data-ga-label="copy">
|
||
Copy
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="article-page" id="article-page" data-article-pmid="34942136">
|
||
<aside class="page-sidebar">
|
||
<div class="inner-wrap">
|
||
|
||
<div class="full-text-links">
|
||
<div class="full-view">
|
||
<h3 class="title">
|
||
Full text links
|
||
</h3>
|
||
<div class="full-text-links-list">
|
||
<a class="link-item
|
||
|
||
dialog-focus"
|
||
href="https://linkinghub.elsevier.com/retrieve/pii/S1474-4422(21)00367-7"
|
||
target="_blank"
|
||
rel="noopener"
|
||
|
||
ref="linksrc=fulltextorjournal_fulltext&is_pmc=False&PrId=3048&itool=Abstract-def&log$=linkouticon&uid=34942136&db=pubmed&nlmid=101139309"
|
||
title="See full text options at Elsevier Science"
|
||
|
||
data-ga-category="full_text"
|
||
data-ga-action="Elsevier Science"
|
||
data-ga-label="34942136"
|
||
><img src="https://cdn.ncbi.nlm.nih.gov/corehtml/query/egifs/https:--linkinghub.elsevier.com-ihub-images-14744422-TLN.gif" alt="Elsevier Science full text link"><span class="text">
|
||
|
||
Elsevier Science
|
||
|
||
</span></a>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
<div class="short-view">
|
||
<a href="#" class="full-text-links-button full-text-links-dialog-trigger">
|
||
Full text links
|
||
</a>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div class="actions-buttons sidebar"><h3 class="title">Actions</h3><div class="inner-wrap"><button class="citation-button citation-dialog-trigger"
|
||
aria-label="Open dialog with citation text in different styles"
|
||
data-ga-category="save_share"
|
||
data-ga-action="cite"
|
||
data-ga-label="open"
|
||
data-all-citations-url="/34942136/citations/"
|
||
data-citation-style="nlm"
|
||
data-pubmed-format-link="/34942136/export/"><span class="button-label">Cite</span></button><link type="text/css" href="ncbi-overlay-block/src/overlay-block.css"><div class="collections-button-container" data-article-id="34942136" data-article-db="pubmed"><button class="collections-button collections-dialog-trigger"
|
||
aria-label="Save article in MyNCBI collections."
|
||
data-ga-category="collections_button"
|
||
data-ga-action="click"
|
||
data-ga-label="collections_button"
|
||
data-collections-open-dialog-enabled="false"
|
||
data-collections-open-dialog-url="https://account.ncbi.nlm.nih.gov/?back_url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F34942136%2F%23open-collections-dialog"
|
||
data-in-collections="false"><span class="button-label">Collections</span></button><div class="overlay" role="dialog"><div id="collections-action-dialog"
|
||
class="dialog collections-dialog"
|
||
aria-hidden="true"><div class="title">Add to Collections</div><div class="collections-action-panel action-panel"><form id="collections-action-dialog-form"
|
||
class="collections-action-panel-form action-panel-content action-form action-panel-smaller-selectors"
|
||
data-existing-collections-url="/list-existing-collections/"
|
||
data-add-to-existing-collection-url="/add-to-existing-collection/"
|
||
data-create-and-add-to-new-collection-url="/create-and-add-to-new-collection/"
|
||
data-myncbi-max-collection-name-length="100"
|
||
data-collections-root-url="https://www.ncbi.nlm.nih.gov/myncbi/collections/"><input type="hidden" name="csrfmiddlewaretoken" value="Ff6FWHvGyDWYw5sPbaxhVURPbDv4sFpjW2QKzxY28eJsqwyFOtajp2ntJHdglgXD"><div class="choice-group" role="radiogroup"><ul class="radio-group-items"><li><input type="radio"
|
||
id="collections-action-dialog-new"
|
||
class="collections-new"
|
||
name="collections"
|
||
value="new"
|
||
data-ga-category="collections_button"
|
||
data-ga-action="click"
|
||
data-ga-label="collections_radio_new"><label for="collections-action-dialog-new">Create a new collection</label></li><li><input type="radio"
|
||
id="collections-action-dialog-existing"
|
||
class="collections-existing"
|
||
name="collections"
|
||
value="existing"
|
||
checked="true"
|
||
data-ga-category="collections_button"
|
||
data-ga-action="click"
|
||
data-ga-label="collections_radio_existing"><label for="collections-action-dialog-existing">Add to an existing collection</label></li></ul></div><div class="controls-wrapper"><div class="action-panel-control-wrap new-collections-controls"><label for="collections-action-dialog-add-to-new" class="action-panel-label required-field-asterisk">
|
||
Name your collection:
|
||
</label><input
|
||
type="text"
|
||
name="add-to-new-collection"
|
||
id="collections-action-dialog-add-to-new"
|
||
class="collections-action-add-to-new"
|
||
pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/"
|
||
maxlength="100"
|
||
data-ga-category="collections_button"
|
||
data-ga-action="create_collection"
|
||
data-ga-label="non_favorties_collection"><div class="collections-new-name-too-long usa-input-error-message selection-validation-message">
|
||
Name must be less than 100 characters
|
||
</div></div><div class="action-panel-control-wrap existing-collections-controls"><label for="collections-action-dialog-add-to-existing" class="action-panel-label">
|
||
Choose a collection:
|
||
</label><select id="collections-action-dialog-add-to-existing"
|
||
class="action-panel-selector collections-action-add-to-existing"
|
||
data-ga-category="collections_button"
|
||
data-ga-action="select_collection"
|
||
data-ga-label="($('.collections-action-add-to-existing').val() === 'Favorites') ? 'Favorites' : 'non_favorites_collection'"></select><div class="collections-retry-load-on-error usa-input-error-message selection-validation-message">
|
||
Unable to load your collection due to an error<br><a href="#">Please try again</a></div></div></div><div class="action-panel-actions"><button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Adding..."
|
||
data-pinger-ignore
|
||
data-ga-category="collections_button"
|
||
data-ga-action="click"
|
||
data-ga-label="add">
|
||
Add
|
||
</button><button class="action-panel-cancel"
|
||
aria-label="Close 'Add to Collections' panel"
|
||
ref="linksrc=close_collections_panel"
|
||
aria-controls="collections-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="collections_button"
|
||
data-ga-action="click"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button></div></form></div></div></div></div><button class="more-actions-button more-actions-dialog-trigger"
|
||
title="Open dialog with more actions to take"
|
||
ref="linksrc=more_actions_btn"></button><div class="display-options" data-format-key="format"
|
||
data-default-format-value="abstract"
|
||
data-current-format-value="abstract" role="region"><button
|
||
class="trigger usa-button"
|
||
title="Change format"
|
||
data-ga-category="display_options"
|
||
data-ga-action="display_options_dialog"><span class="button-label">Display options</span></button><div class="dropdown" hidden><div class="title">
|
||
Display options
|
||
</div><div class="content"><div class="format-container"><span class="option-label">
|
||
Format
|
||
</span><select name="format" data-initial-value="abstract" aria-label="Display format" id="sidebar-actions-display-format"><option value="abstract">Abstract</option><option value="pubmed">PubMed</option><option value="pmid">PMID</option></select></div></div></div></div></div></div>
|
||
|
||
<div class="social-sharing">
|
||
<h3 class="title">
|
||
Share
|
||
</h3>
|
||
<ul class="social-sharing-links usa-unstyled-list">
|
||
|
||
|
||
<li>
|
||
<a href="http://twitter.com/intent/tweet?text=Safety%20and%20efficacy%20of%20once-daily%20risdiplam%20in%20type%202%20and%20non-ambulant%20type%203%20spinal%20muscular%20atrophy%20%28SUNFISH%20part%E2%80%A6%20https%3A//pubmed.ncbi.nlm.nih.gov/34942136/"
|
||
class="share-link share-link-twitter"
|
||
rel="noreferrer noopener"
|
||
target="Pubmed-Social-Media-Share-Popup"
|
||
title="Share article on Twitter"
|
||
data-ga-category="save_share"
|
||
data-ga-action="social"
|
||
data-ga-label="twitter"></a>
|
||
</li>
|
||
<li>
|
||
<a href="http://www.facebook.com/sharer/sharer.php?u=https%3A//pubmed.ncbi.nlm.nih.gov/34942136/"
|
||
class="share-link share-link-facebook"
|
||
rel="noreferrer noopener"
|
||
target="Pubmed-Social-Media-Share-Popup"
|
||
title="Share article on Facebook"
|
||
data-ga-category="save_share"
|
||
data-ga-action="social"
|
||
data-ga-label="fb"></a>
|
||
</li>
|
||
|
||
<li>
|
||
<div class="share-permalink">
|
||
<button class="trigger"
|
||
title="Show article permalink"
|
||
ref="linksrc=show_permalink_btn">
|
||
</button>
|
||
<div class="dropdown" hidden>
|
||
<div class="title">
|
||
Permalink
|
||
</div>
|
||
<div class="content">
|
||
|
||
|
||
<input type="text"
|
||
class="permalink-text"
|
||
value="https://pubmed.ncbi.nlm.nih.gov/34942136/"
|
||
aria-label="Article permalink"/><button class="permalink-copy-button usa-button-primary"
|
||
title="Copy article permalink"
|
||
data-ga-category="save_share"
|
||
data-ga-action="link"
|
||
data-ga-label="copy_link"><span class="button-title">Copy</span></button>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
|
||
<nav class="page-navigator" role="navigation" aria-label="Page navigation">
|
||
<div class="full-view">
|
||
<h3 class="title">
|
||
Page navigation
|
||
</h3>
|
||
<ul class="items-list">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<li class="heading ">
|
||
<a href="#heading"
|
||
aria-label="navigate to Title & authors section"
|
||
data-ga-category="page_nav"
|
||
data-ga-action="heading">
|
||
Title & authors
|
||
</a>
|
||
</li>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<li class="linked-correction-forward current">
|
||
<a href="#linked-correction-forward"
|
||
aria-label="navigate to Erratum in section"
|
||
data-ga-category="page_nav"
|
||
data-ga-action="linked-correction-forward">
|
||
Erratum in
|
||
</a>
|
||
</li>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<li class="abstract ">
|
||
<a href="#abstract"
|
||
aria-label="navigate to Abstract section"
|
||
data-ga-category="page_nav"
|
||
data-ga-action="abstract">
|
||
Abstract
|
||
</a>
|
||
</li>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<li class="conflict-of-interest ">
|
||
<a href="#conflict-of-interest"
|
||
aria-label="navigate to Conflict of interest statement section"
|
||
data-ga-category="page_nav"
|
||
data-ga-action="conflict-of-interest">
|
||
Conflict of interest statement
|
||
</a>
|
||
</li>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<li class="linked-commentary-article current">
|
||
<a href="#linked-commentary-article"
|
||
aria-label="navigate to Comment on section"
|
||
data-ga-category="page_nav"
|
||
data-ga-action="linked-commentary-article">
|
||
Comment on
|
||
</a>
|
||
</li>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<li class="similar ">
|
||
<a href="#similar"
|
||
aria-label="navigate to Similar articles section"
|
||
data-ga-category="page_nav"
|
||
data-ga-action="similar">
|
||
Similar articles
|
||
</a>
|
||
</li>
|
||
|
||
|
||
|
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|
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|
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|
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|
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<h1 class="heading-title">
|
||
|
||
|
||
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||
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||
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||
|
||
Safety and efficacy of once-daily risdiplam in type 2 and non-ambulant type 3 spinal muscular atrophy (SUNFISH part 2): a phase 3, double-blind, randomised, placebo-controlled trial
|
||
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||
|
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|
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<span class="authors-list-item "><span class="full-name">Eugenio Mercuri</span><span class="citation-separator"> et al.</span></span>
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Correction to Lancet Neurol 2022; 21: 42-52.
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<span class="docsum-journal-citation full-journal-citation">Lancet Neurol. 2022 Feb;21(2):e2. doi: 10.1016/S1474-4422(22)00006-0.</span>
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<span class="docsum-journal-citation short-journal-citation">Lancet Neurol. 2022.</span>
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<span class="docsum-journal-citation full-journal-citation">Lancet Neurol. 2022 Mar;21(3):e3. doi: 10.1016/S1474-4422(22)00038-2.</span>
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<span class="docsum-journal-citation short-journal-citation">Lancet Neurol. 2022.</span>
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<span class="no-abstract spaced-citation-item citation-part">No abstract available.</span>
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|
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<span class="docsum-journal-citation full-journal-citation">Lancet Neurol. 2022 May;21(5):e5. doi: 10.1016/S1474-4422(22)00141-7.</span>
|
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|
||
Abstract
|
||
|
||
</h2>
|
||
|
||
|
||
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<div class="abstract-content selected"
|
||
id="eng-abstract">
|
||
|
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|
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|
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|
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|
||
<p>
|
||
|
||
<strong class="sub-title">
|
||
Background:
|
||
</strong>
|
||
|
||
Risdiplam is an oral small molecule approved for the treatment of patients with spinal muscular atrophy, with approval for use in patients with type 2 and type 3 spinal muscular atrophy granted on the basis of unpublished data. The drug modifies pre-mRNA splicing of the SMN2 gene to increase production of functional SMN. We aimed to investigate the safety and efficacy of risdiplam in patients with type 2 or non-ambulant type 3 spinal muscular atrophy.
|
||
</p>
|
||
|
||
|
||
|
||
|
||
|
||
|
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|
||
|
||
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||
|
||
<p>
|
||
|
||
<strong class="sub-title">
|
||
Methods:
|
||
</strong>
|
||
|
||
In this phase 3, randomised, double-blind, placebo-controlled study, patients aged 2-25 years with confirmed 5q autosomal recessive type 2 or type 3 spinal muscular atrophy were recruited from 42 hospitals in 14 countries across Europe, North America, South America, and Asia. Participants were eligible if they were non-ambulant, could sit independently, and had a score of at least 2 in entry item A of the Revised Upper Limb Module. Patients were stratified by age and randomly assigned (2:1) to receive either daily oral risdiplam, at a dose of 5·00 mg (for individuals weighing ≥20 kg) or 0·25 mg/kg (for individuals weighing <20 kg), or daily oral placebo (matched to risdiplam in colour and taste). Randomisation was conducted by permutated block randomisation with a computerised system run by an external party. Patients, investigators, and all individuals in direct contact with patients were masked to treatment assignment. The primary endpoint was the change from baseline in the 32-item Motor Function Measure total score at month 12. All individuals who were randomly assigned to risdiplam or placebo, and who did not meet the prespecified missing item criteria for exclusion, were included in the primary efficacy analysis. Individuals who received at least one dose of risdiplam or placebo were included in the safety analysis. SUNFISH is registered with ClinicalTrials.gov, <a href="http://clinicaltrials.gov/show/NCT02908685" title="See in ClinicalTrials.gov">NCT02908685</a>. Recruitment is closed; the study is ongoing.
|
||
</p>
|
||
|
||
|
||
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||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<p>
|
||
|
||
<strong class="sub-title">
|
||
Findings:
|
||
</strong>
|
||
|
||
Between Oct 9, 2017, and Sept 4, 2018, 180 patients were randomly assigned to receive risdiplam (n=120) or placebo (n=60). For analysis of the primary endpoint, 115 patients from the risdiplam group and 59 patients from the placebo group were included. At month 12, the least squares mean change from baseline in 32-item Motor Function Measure was 1·36 (95% CI 0·61 to 2·11) in the risdiplam group and -0·19 (-1·22 to 0·84) in the placebo group, with a treatment difference of 1·55 (0·30 to 2·81, p=0·016) in favour of risdiplam. 120 patients who received risdiplam and 60 who received placebo were included in safety analyses. Adverse events that were reported in at least 5% more patients who received risdiplam than those who received placebo were pyrexia (25 [21%] of 120 patients who received risdiplam vs ten [17%] of 60 patients who received placebo), diarrhoea (20 [17%] vs five [8%]), rash (20 [17%] vs one [2%]), mouth and aphthous ulcers (eight [7%] vs 0), urinary tract infection (eight [7%] vs 0), and arthralgias (six [5%] vs 0). The incidence of serious adverse events was similar between treatment groups (24 [20%] of 120 patients in the risdiplam group; 11 [18%] of 60 patients in the placebo group), with the exception of pneumonia (nine [8%] in the risdiplam group; one [2%] in the placebo group).
|
||
</p>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<p>
|
||
|
||
<strong class="sub-title">
|
||
Interpretation:
|
||
</strong>
|
||
|
||
Risdiplam resulted in a significant improvement in motor function compared with placebo in patients aged 2-25 years with type 2 or non-ambulant type 3 spinal muscular atrophy. Our exploratory subgroup analyses showed that motor function was generally improved in younger individuals and stabilised in older individuals, which requires confirmation in further studies. SUNFISH part 2 is ongoing and will provide additional evidence regarding the long-term safety and efficacy of risdiplam.
|
||
</p>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<p>
|
||
|
||
<strong class="sub-title">
|
||
Funding:
|
||
</strong>
|
||
|
||
F Hoffmann-La Roche.
|
||
</p>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<p class="copyright" id="copyright">
|
||
Copyright © 2022 Elsevier Ltd. All rights reserved.
|
||
</p>
|
||
|
||
|
||
<p class="disclaimer" id="disclaimer">
|
||
<a href="/disclaimer/" target="_blank" data-ga-category="literature_resources"
|
||
data-ga-action="disclaimer_link" data-ga-label="under_abstract">PubMed Disclaimer</a>
|
||
</p>
|
||
|
||
<div class="conflict-of-interest" id="conflict-of-interest">
|
||
<h2 class="title">
|
||
Conflict of interest statement
|
||
</h2>
|
||
|
||
<div class="statement">
|
||
|
||
|
||
|
||
<p xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:p1="http://pubmed.gov/pub-one">Declaration of interests EM has received fees for serving on scientific advisory boards; speaker fees from F Hoffmann-La Roche, Biogen, AveXis/Novartis, Scholar Rock, and Cytokinetics; and grants from Biogen during the conduct of the study. ND served on scientific advisory boards for F Hoffmann-La Roche and Novartis pharmaceuticals; he has received personal fees from Biogen for congress and travel support. ESM reports that she has served on advisory boards for Biogen and Scholar Rock. She has received consulting fees, travel support, and speaker honoraria as an independent contractor from F Hoffmann-La Roche, Biogen, AveXis, and Scholar Rock. AN has received fees for serving on scientific advisory boards and speaker fees from F Hoffmann-La Roche. MO reports grants from F Hoffmann-La Roche during the conduct of the study and has received grants as a clinical trial investigator from Biogen. KS reports grants from F Hoffman-La Roche/Chugai Pharmaceutical during the conduct of the study and grants from Biogen Japan and lecture fees from Novartis Pharmaceuticals, outside the submitted work. CV reports personal fees and financial support to her institution from F Hoffmann-La Roche for activities outside the submitted work. GB received consultancy fees and speaker honoraria from F Hoffmann-La Roche and AveXis and speaker fees from PTC Therapeutics. NG reports fees for serving on advisory boards and presentations at symposia from F Hoffmann-La Roche, Biogen, and AveXis. JK received grants or contracts from Novartis Gene Therapies and Biogen. He has received consulting and speaker fees from F Hoffmann La Roche, Biogen, and Novartis Gene Therapies and consulting fees from Scholar Rock. AK-P reports that she received an institutional support grant from Biogen; serving on scientific advisory boards for and receiving speaker honoraria from Biogen, F Hoffmann-La Roche, Novartis, and PTC Therapeutics; and receiving personal fees from Biogen and F Hoffmann-La Roche for travel support. LS received grants and personal fees from F Hoffman-La Roche, Biogen, and AveXis/Novartis Gene Therapy and personal fees from Cytokinetics, outside the submitted work. OK reports that he was previously an employee and stockholder in F Hoffmann-La Roche during the submitted work and that he now holds the position of honorary chief medical officer at The Spinal Muscular Atrophy Foundation. JWD has received fees for serving on scientific advisory boards from Biogen, Novartis, Sarepta, and Avidity; has received consulting fees from Affinia Therapeutics and Shift Therapeutics for a therapeutic platform; and has received grant support for clinical trials from F Hoffman-La Roche, Biogen, Novartis Gene Therapies, Cytokinetics, Scholar Rock, and Sarepta. CM, PF, MG, KG, HK, HS, RSS, and WYY report that they are current employees and stockholders in F Hoffmann-La Roche. OB-T declared no competing interests.</p>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="linked-articles" id="linked-commentary-article">
|
||
<h2 class="title">
|
||
Comment on
|
||
</h2>
|
||
<ul class="item-list usa-unstyled-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li class="full-docsum">
|
||
|
||
<div class="docsum-content" style="display:inline;">
|
||
<a class="docsum-title"
|
||
href="/34942130/"
|
||
ref="article_id=34942130&linksrc=comments_link"
|
||
data-ga-category="comment_correction"
|
||
data-ga-action="abstract_page_link"
|
||
data-ga-label="linked-commentary-article">
|
||
|
||
Risdiplam: new opportunities but more to be done.
|
||
|
||
</a>
|
||
<div class="docsum-citation full-citation">
|
||
|
||
|
||
|
||
<span class="docsum-authors full-authors">Sansone VA.</span>
|
||
|
||
|
||
|
||
<span class="docsum-authors short-authors">Sansone VA.</span>
|
||
<span class="docsum-journal-citation full-journal-citation">Lancet Neurol. 2022 Jan;21(1):23-24. doi: 10.1016/S1474-4422(21)00428-2.</span>
|
||
<span class="docsum-journal-citation short-journal-citation">Lancet Neurol. 2022.</span>
|
||
|
||
|
||
<span class="citation-part">PMID: <span class="docsum-pmid">34942130</span></span>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<span class="no-abstract spaced-citation-item citation-part">No abstract available.</span>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
|
||
</ul>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
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|
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<span class="docsum-authors short-authors">Oskoui M, et al.</span>
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||
<span class="docsum-journal-citation short-journal-citation">PLoS One. 2024.</span>
|
||
|
||
|
||
<span class="citation-part">PMID: <span class="docsum-pmid">39088538</span></span>
|
||
<span class="free-resources spaced-citation-item citation-part">Free PMC article.</span>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
</div>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<li class="full-docsum">
|
||
|
||
<div class="docsum-content" style="display:inline;">
|
||
<a class="docsum-title"
|
||
href="/35734367/"
|
||
ref="article_id=35734367&linksrc=citedby_articles_link&ordinalpos=2"
|
||
data-ga-category="cited_by"
|
||
data-ga-action="35734367"
|
||
data-ga-label="">
|
||
|
||
Disease Modifying Therapies for the Management of Children with Spinal Muscular Atrophy (5q SMA): An Update on the Emerging Evidence.
|
||
|
||
</a>
|
||
<div class="docsum-citation full-citation">
|
||
|
||
|
||
|
||
<span class="docsum-authors full-authors">Hjartarson HT, Nathorst-Böös K, Sejersen T.</span>
|
||
|
||
|
||
|
||
<span class="docsum-authors short-authors">Hjartarson HT, et al.</span>
|
||
<span class="docsum-journal-citation full-journal-citation">Drug Des Devel Ther. 2022 Jun 16;16:1865-1883. doi: 10.2147/DDDT.S214174. eCollection 2022.</span>
|
||
<span class="docsum-journal-citation short-journal-citation">Drug Des Devel Ther. 2022.</span>
|
||
|
||
|
||
<span class="citation-part">PMID: <span class="docsum-pmid">35734367</span></span>
|
||
<span class="free-resources spaced-citation-item citation-part">Free PMC article.</span>
|
||
|
||
|
||
|
||
<span class="publication-type spaced-citation-item citation-part">Review.</span>
|
||
|
||
|
||
</div>
|
||
|
||
</div>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<li class="full-docsum">
|
||
|
||
<div class="docsum-content" style="display:inline;">
|
||
<a class="docsum-title"
|
||
href="/37877676/"
|
||
ref="article_id=37877676&linksrc=citedby_articles_link&ordinalpos=3"
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||
data-ga-category="cited_by"
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data-ga-action="37877676"
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|
||
|
||
Spinal muscular atrophy: Should we prescribe approved drugs to cohorts of patients in which they are unproven?
|
||
|
||
</a>
|
||
<div class="docsum-citation full-citation">
|
||
|
||
|
||
|
||
<span class="docsum-authors full-authors">Fontanelli L, Di Rauso G, Bellini G.</span>
|
||
|
||
|
||
|
||
<span class="docsum-authors short-authors">Fontanelli L, et al.</span>
|
||
<span class="docsum-journal-citation full-journal-citation">Eur J Neurol. 2024 Feb;31(2):e16103. doi: 10.1111/ene.16103. Epub 2023 Oct 25.</span>
|
||
<span class="docsum-journal-citation short-journal-citation">Eur J Neurol. 2024.</span>
|
||
|
||
|
||
<span class="citation-part">PMID: <span class="docsum-pmid">37877676</span></span>
|
||
<span class="free-resources spaced-citation-item citation-part">Free PMC article.</span>
|
||
|
||
|
||
|
||
|
||
|
||
<span class="no-abstract spaced-citation-item citation-part">No abstract available.</span>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<li class="full-docsum">
|
||
|
||
<div class="docsum-content" style="display:inline;">
|
||
<a class="docsum-title"
|
||
href="/38678519/"
|
||
ref="article_id=38678519&linksrc=citedby_articles_link&ordinalpos=4"
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data-ga-category="cited_by"
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data-ga-action="38678519"
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|
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|
||
Molecular mechanisms and therapeutic strategies for neuromuscular diseases.
|
||
|
||
</a>
|
||
<div class="docsum-citation full-citation">
|
||
|
||
|
||
|
||
<span class="docsum-authors full-authors">Zambon AA, Falzone YM, Bolino A, Previtali SC.</span>
|
||
|
||
|
||
|
||
<span class="docsum-authors short-authors">Zambon AA, et al.</span>
|
||
<span class="docsum-journal-citation full-journal-citation">Cell Mol Life Sci. 2024 Apr 28;81(1):198. doi: 10.1007/s00018-024-05229-9.</span>
|
||
<span class="docsum-journal-citation short-journal-citation">Cell Mol Life Sci. 2024.</span>
|
||
|
||
|
||
<span class="citation-part">PMID: <span class="docsum-pmid">38678519</span></span>
|
||
<span class="free-resources spaced-citation-item citation-part">Free PMC article.</span>
|
||
|
||
|
||
|
||
<span class="publication-type spaced-citation-item citation-part">Review.</span>
|
||
|
||
|
||
</div>
|
||
|
||
</div>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<li class="full-docsum">
|
||
|
||
<div class="docsum-content" style="display:inline;">
|
||
<a class="docsum-title"
|
||
href="/36995385/"
|
||
ref="article_id=36995385&linksrc=citedby_articles_link&ordinalpos=5"
|
||
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data-ga-action="36995385"
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|
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[Update on drug treatment of spinal muscular atrophy].
|
||
|
||
</a>
|
||
<div class="docsum-citation full-citation">
|
||
|
||
|
||
|
||
<span class="docsum-authors full-authors">Kölbel H, Hagenacker T.</span>
|
||
|
||
|
||
|
||
<span class="docsum-authors short-authors">Kölbel H, et al.</span>
|
||
<span class="docsum-journal-citation full-journal-citation">Nervenarzt. 2023 Jun;94(6):488-493. doi: 10.1007/s00115-023-01462-y. Epub 2023 Mar 30.</span>
|
||
<span class="docsum-journal-citation short-journal-citation">Nervenarzt. 2023.</span>
|
||
|
||
|
||
<span class="citation-part">PMID: <span class="docsum-pmid">36995385</span></span>
|
||
|
||
|
||
|
||
|
||
<span class="publication-type spaced-citation-item citation-part">Review.</span>
|
||
<span class="language spaced-citation-item citation-part">German.</span>
|
||
|
||
</div>
|
||
|
||
</div>
|
||
|
||
</li>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</ul>
|
||
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||
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<div class="actions-bar">
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<a
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|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div id="publication-types" class="publication-types keywords-section">
|
||
<h2 class="title">
|
||
Publication types
|
||
</h2>
|
||
|
||
<ul class="keywords-list"><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
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aria-label="Toggle dropdown menu for keyword Research Support, Non-U.S. Gov't"
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tabindex="0"
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aria-expanded="false"
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data-pinger-ignore>
|
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Research Support, Non-U.S. Gov't
|
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</button><div id="keyword-actions-publication-types-0"
|
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class="keyword-actions-dropdown dropdown dropdown-container"
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hidden
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aria-label="Dropdown menu for keyword Research Support, Non-U.S. Gov't"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
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href="/?term=%22Research+Support%2C+Non-U.S.+Gov%27t%22%5Bpt%5D&sort=date&sort_order=desc"
|
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data-href="/?term=%22Research+Support%2C+Non-U.S.+Gov%27t%22%5Bpt%5D&sort=date&sort_order=desc"
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ref="linksrc=search_in_pubmed_keyword_link&keyword="Research Support, Non-U.S. Gov't"[pt]"
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Search in MeSH
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ref="linksrc=add_to_search_link"
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data-search-term=""Research Support, Non-U.S. Gov't"[pt]"
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data-ga-category="search"
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Add to Search
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
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aria-label="Toggle dropdown menu for keyword Comment"
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tabindex="0"
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aria-expanded="false"
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data-pinger-ignore>
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Comment
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</button><div id="keyword-actions-publication-types-1"
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class="keyword-actions-dropdown dropdown dropdown-container"
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hidden
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aria-label="Dropdown menu for keyword Comment"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
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href="/?term=%22Comment%22%5Bpt%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Comment%22%5Bpt%5D&sort=date&sort_order=desc"
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ref="linksrc=search_in_pubmed_keyword_link&keyword="Comment"[pt]"
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Search in PubMed
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Search in MeSH
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|
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|
||
<div id="mesh-terms" class="mesh-terms keywords-section">
|
||
<h2 class="title">
|
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MeSH terms
|
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</h2>
|
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|
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<ul class="keywords-list"><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
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Adolescent
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</button><div id="keyword-actions-mesh-terms-0"
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class="keyword-actions-dropdown dropdown dropdown-container"
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hidden
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aria-label="Dropdown menu for keyword Adolescent"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
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href="/?term=%22Adolescent%22%5BMeSH%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Adolescent%22%5BMeSH%5D&sort=date&sort_order=desc"
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
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aria-label="Toggle dropdown menu for keyword Adult"
|
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tabindex="0"
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aria-expanded="false"
|
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data-pinger-ignore>
|
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Adult
|
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</button><div id="keyword-actions-mesh-terms-1"
|
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class="keyword-actions-dropdown dropdown dropdown-container"
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hidden
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aria-label="Dropdown menu for keyword Adult"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
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href="/?term=%22Adult%22%5BMeSH%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Adult%22%5BMeSH%5D&sort=date&sort_order=desc"
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Adult"[MeSH]"
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data-ga-category="search"
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data-ga-action="mesh_term"
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Search in PubMed
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data-ga-category="search_mesh"
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data-ga-action="mesh_term_link"
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Search in MeSH
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data-search-term=""Adult"[MeSH]"
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data-ga-category="search"
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data-ga-action="add_to_search"
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
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aria-label="Toggle dropdown menu for keyword Aged"
|
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tabindex="0"
|
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|
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aria-expanded="false"
|
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data-pinger-ignore>
|
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Aged
|
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</button><div id="keyword-actions-mesh-terms-2"
|
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class="keyword-actions-dropdown dropdown dropdown-container"
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hidden
|
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aria-label="Dropdown menu for keyword Aged"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
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href="/?term=%22Aged%22%5BMeSH%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Aged%22%5BMeSH%5D&sort=date&sort_order=desc"
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Aged"[MeSH]"
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Search in PubMed
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
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aria-label="Toggle dropdown menu for keyword Azo Compounds / adverse effects"
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aria-expanded="false"
|
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data-pinger-ignore>
|
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Azo Compounds / adverse effects
|
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</button><div id="keyword-actions-mesh-terms-3"
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href="/?term=%22Azo+Compounds%2Fadverse+effects%22%5BMeSH%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Azo+Compounds%2Fadverse+effects%22%5BMeSH%5D&sort=date&sort_order=desc"
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Azo Compounds/adverse effects"[MeSH]"
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data-ga-category="search"
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Add to Search
|
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
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aria-label="Toggle dropdown menu for keyword Child"
|
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tabindex="0"
|
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|
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aria-expanded="false"
|
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data-pinger-ignore>
|
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Child
|
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</button><div id="keyword-actions-mesh-terms-4"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Child"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Child%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Child%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
ref="linksrc=search_in_pubmed_keyword_link&mesh="Child"[MeSH]"
|
||
data-ga-category="search"
|
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data-ga-action="mesh_term"
|
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data-ga-label="Child">
|
||
Search in PubMed
|
||
</a></li><li><a class="search-in-mesh-link dropdown-block-link"
|
||
ref="linksrc=search_in_mesh_link"
|
||
href="https://www.ncbi.nlm.nih.gov/mesh?term=Child"
|
||
data-ga-category="search_mesh"
|
||
data-ga-action="mesh_term_link"
|
||
data-ga-label="Child">
|
||
Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
||
ref="linksrc=add_to_search_link"
|
||
role="button"
|
||
data-search-term=""Child"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="add_to_search"
|
||
data-ga-label=""Child"[MeSH]"
|
||
href="#">
|
||
Add to Search
|
||
</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
||
aria-label="Toggle dropdown menu for keyword Child, Preschool"
|
||
tabindex="0"
|
||
aria-controls="keyword-actions-mesh-terms-5"
|
||
aria-expanded="false"
|
||
data-pinger-ignore>
|
||
Child, Preschool
|
||
</button><div id="keyword-actions-mesh-terms-5"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Child, Preschool"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Child%2C+Preschool%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Child%2C+Preschool%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
ref="linksrc=search_in_pubmed_keyword_link&mesh="Child, Preschool"[MeSH]"
|
||
data-ga-category="search"
|
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data-ga-action="mesh_term"
|
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data-ga-label="Child, Preschool">
|
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Search in PubMed
|
||
</a></li><li><a class="search-in-mesh-link dropdown-block-link"
|
||
ref="linksrc=search_in_mesh_link"
|
||
href="https://www.ncbi.nlm.nih.gov/mesh?term=Child%2C+Preschool"
|
||
data-ga-category="search_mesh"
|
||
data-ga-action="mesh_term_link"
|
||
data-ga-label="Child, Preschool">
|
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Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
||
ref="linksrc=add_to_search_link"
|
||
role="button"
|
||
data-search-term=""Child, Preschool"[MeSH]"
|
||
data-ga-category="search"
|
||
data-ga-action="add_to_search"
|
||
data-ga-label=""Child, Preschool"[MeSH]"
|
||
href="#">
|
||
Add to Search
|
||
</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
||
aria-label="Toggle dropdown menu for keyword Double-Blind Method"
|
||
tabindex="0"
|
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aria-controls="keyword-actions-mesh-terms-6"
|
||
aria-expanded="false"
|
||
data-pinger-ignore>
|
||
Double-Blind Method
|
||
</button><div id="keyword-actions-mesh-terms-6"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Double-Blind Method"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Double-Blind+Method%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Double-Blind+Method%22%5BMeSH%5D&sort=date&sort_order=desc"
|
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Double-Blind Method"[MeSH]"
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data-ga-category="search"
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data-ga-action="mesh_term"
|
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data-ga-label="Double-Blind Method">
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Search in PubMed
|
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</a></li><li><a class="search-in-mesh-link dropdown-block-link"
|
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ref="linksrc=search_in_mesh_link"
|
||
href="https://www.ncbi.nlm.nih.gov/mesh?term=Double-Blind+Method"
|
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data-ga-category="search_mesh"
|
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data-ga-action="mesh_term_link"
|
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data-ga-label="Double-Blind Method">
|
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Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
||
ref="linksrc=add_to_search_link"
|
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role="button"
|
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data-search-term=""Double-Blind Method"[MeSH]"
|
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data-ga-category="search"
|
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data-ga-action="add_to_search"
|
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data-ga-label=""Double-Blind Method"[MeSH]"
|
||
href="#">
|
||
Add to Search
|
||
</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
||
aria-label="Toggle dropdown menu for keyword Humans"
|
||
tabindex="0"
|
||
aria-controls="keyword-actions-mesh-terms-7"
|
||
aria-expanded="false"
|
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data-pinger-ignore>
|
||
Humans
|
||
</button><div id="keyword-actions-mesh-terms-7"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Humans"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Humans%22%5BMeSH%5D&sort=date&sort_order=desc"
|
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data-href="/?term=%22Humans%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
ref="linksrc=search_in_pubmed_keyword_link&mesh="Humans"[MeSH]"
|
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data-ga-category="search"
|
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data-ga-action="mesh_term"
|
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data-ga-label="Humans">
|
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Search in PubMed
|
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</a></li><li><a class="search-in-mesh-link dropdown-block-link"
|
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ref="linksrc=search_in_mesh_link"
|
||
href="https://www.ncbi.nlm.nih.gov/mesh?term=Humans"
|
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data-ga-category="search_mesh"
|
||
data-ga-action="mesh_term_link"
|
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data-ga-label="Humans">
|
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Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
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ref="linksrc=add_to_search_link"
|
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role="button"
|
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data-search-term=""Humans"[MeSH]"
|
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data-ga-category="search"
|
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data-ga-action="add_to_search"
|
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data-ga-label=""Humans"[MeSH]"
|
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href="#">
|
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Add to Search
|
||
</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link major"
|
||
aria-label="Toggle dropdown menu for keyword Pyrimidines* / adverse effects"
|
||
tabindex="0"
|
||
aria-controls="keyword-actions-mesh-terms-major-8"
|
||
aria-expanded="false"
|
||
data-pinger-ignore>
|
||
Pyrimidines* / adverse effects
|
||
</button><div id="keyword-actions-mesh-terms-major-8"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Pyrimidines* / adverse effects"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Pyrimidines%2Fadverse+effects%22%5BMAJR%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Pyrimidines%2Fadverse+effects%22%5BMAJR%5D&sort=date&sort_order=desc"
|
||
ref="linksrc=search_in_pubmed_keyword_link&mesh="Pyrimidines/adverse effects"[MAJR]"
|
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data-ga-category="search"
|
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data-ga-action="mesh_term"
|
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data-ga-label="Pyrimidines* / adverse effects">
|
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Search in PubMed
|
||
</a></li><li><a class="search-in-mesh-link dropdown-block-link"
|
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ref="linksrc=search_in_mesh_link"
|
||
href="https://www.ncbi.nlm.nih.gov/mesh?term=Pyrimidines"
|
||
data-ga-category="search_mesh"
|
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data-ga-action="mesh_term_link"
|
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data-ga-label="Pyrimidines* / adverse effects">
|
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Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
||
ref="linksrc=add_to_search_link"
|
||
role="button"
|
||
data-search-term=""Pyrimidines/adverse effects"[MAJR]"
|
||
data-ga-category="search"
|
||
data-ga-action="add_to_search"
|
||
data-ga-label=""Pyrimidines/adverse effects"[MAJR]"
|
||
href="#">
|
||
Add to Search
|
||
</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link major"
|
||
aria-label="Toggle dropdown menu for keyword Spinal Muscular Atrophies of Childhood* / drug therapy"
|
||
tabindex="0"
|
||
aria-controls="keyword-actions-mesh-terms-major-9"
|
||
aria-expanded="false"
|
||
data-pinger-ignore>
|
||
Spinal Muscular Atrophies of Childhood* / drug therapy
|
||
</button><div id="keyword-actions-mesh-terms-major-9"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Spinal Muscular Atrophies of Childhood* / drug therapy"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Spinal+Muscular+Atrophies+of+Childhood%2Fdrug+therapy%22%5BMAJR%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Spinal+Muscular+Atrophies+of+Childhood%2Fdrug+therapy%22%5BMAJR%5D&sort=date&sort_order=desc"
|
||
ref="linksrc=search_in_pubmed_keyword_link&mesh="Spinal Muscular Atrophies of Childhood/drug therapy"[MAJR]"
|
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data-ga-category="search"
|
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data-ga-action="mesh_term"
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data-ga-label="Spinal Muscular Atrophies of Childhood* / drug therapy">
|
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Search in PubMed
|
||
</a></li><li><a class="search-in-mesh-link dropdown-block-link"
|
||
ref="linksrc=search_in_mesh_link"
|
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href="https://www.ncbi.nlm.nih.gov/mesh?term=Spinal+Muscular+Atrophies+of+Childhood"
|
||
data-ga-category="search_mesh"
|
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data-ga-action="mesh_term_link"
|
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data-ga-label="Spinal Muscular Atrophies of Childhood* / drug therapy">
|
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Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
||
ref="linksrc=add_to_search_link"
|
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role="button"
|
||
data-search-term=""Spinal Muscular Atrophies of Childhood/drug therapy"[MAJR]"
|
||
data-ga-category="search"
|
||
data-ga-action="add_to_search"
|
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data-ga-label=""Spinal Muscular Atrophies of Childhood/drug therapy"[MAJR]"
|
||
href="#">
|
||
Add to Search
|
||
</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link major"
|
||
aria-label="Toggle dropdown menu for keyword Spinal Muscular Atrophies of Childhood* / physiopathology"
|
||
tabindex="0"
|
||
aria-controls="keyword-actions-mesh-terms-major-10"
|
||
aria-expanded="false"
|
||
data-pinger-ignore>
|
||
Spinal Muscular Atrophies of Childhood* / physiopathology
|
||
</button><div id="keyword-actions-mesh-terms-major-10"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Spinal Muscular Atrophies of Childhood* / physiopathology"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Spinal+Muscular+Atrophies+of+Childhood%2Fphysiopathology%22%5BMAJR%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Spinal+Muscular+Atrophies+of+Childhood%2Fphysiopathology%22%5BMAJR%5D&sort=date&sort_order=desc"
|
||
ref="linksrc=search_in_pubmed_keyword_link&mesh="Spinal Muscular Atrophies of Childhood/physiopathology"[MAJR]"
|
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data-ga-category="search"
|
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data-ga-action="mesh_term"
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data-ga-label="Spinal Muscular Atrophies of Childhood* / physiopathology">
|
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Search in PubMed
|
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</a></li><li><a class="search-in-mesh-link dropdown-block-link"
|
||
ref="linksrc=search_in_mesh_link"
|
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href="https://www.ncbi.nlm.nih.gov/mesh?term=Spinal+Muscular+Atrophies+of+Childhood"
|
||
data-ga-category="search_mesh"
|
||
data-ga-action="mesh_term_link"
|
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data-ga-label="Spinal Muscular Atrophies of Childhood* / physiopathology">
|
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Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
||
ref="linksrc=add_to_search_link"
|
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role="button"
|
||
data-search-term=""Spinal Muscular Atrophies of Childhood/physiopathology"[MAJR]"
|
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data-ga-category="search"
|
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data-ga-action="add_to_search"
|
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data-ga-label=""Spinal Muscular Atrophies of Childhood/physiopathology"[MAJR]"
|
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href="#">
|
||
Add to Search
|
||
</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
||
aria-label="Toggle dropdown menu for keyword Young Adult"
|
||
tabindex="0"
|
||
aria-controls="keyword-actions-mesh-terms-11"
|
||
aria-expanded="false"
|
||
data-pinger-ignore>
|
||
Young Adult
|
||
</button><div id="keyword-actions-mesh-terms-11"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Young Adult"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Young+Adult%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Young+Adult%22%5BMeSH%5D&sort=date&sort_order=desc"
|
||
ref="linksrc=search_in_pubmed_keyword_link&mesh="Young Adult"[MeSH]"
|
||
data-ga-category="search"
|
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data-ga-action="mesh_term"
|
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data-ga-label="Young Adult">
|
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Search in PubMed
|
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</a></li><li><a class="search-in-mesh-link dropdown-block-link"
|
||
ref="linksrc=search_in_mesh_link"
|
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href="https://www.ncbi.nlm.nih.gov/mesh?term=Young+Adult"
|
||
data-ga-category="search_mesh"
|
||
data-ga-action="mesh_term_link"
|
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data-ga-label="Young Adult">
|
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Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
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ref="linksrc=add_to_search_link"
|
||
role="button"
|
||
data-search-term=""Young Adult"[MeSH]"
|
||
data-ga-category="search"
|
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data-ga-action="add_to_search"
|
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data-ga-label=""Young Adult"[MeSH]"
|
||
href="#">
|
||
Add to Search
|
||
</a></li></ul></div></div></div></li></ul>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
<div id="substances" class="substances keywords-section">
|
||
<h2 class="title">
|
||
Substances
|
||
</h2>
|
||
|
||
<ul class="keywords-list"><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
||
aria-label="Toggle dropdown menu for keyword Azo Compounds"
|
||
tabindex="0"
|
||
aria-controls="keyword-actions-substances-0"
|
||
aria-expanded="false"
|
||
data-pinger-ignore>
|
||
Azo Compounds
|
||
</button><div id="keyword-actions-substances-0"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Azo Compounds"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Azo+Compounds%22%5Bnm%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Azo+Compounds%22%5Bnm%5D&sort=date&sort_order=desc"
|
||
ref="linksrc=search_in_pubmed_keyword_link&keyword="Azo Compounds"[nm]"
|
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data-ga-category="search"
|
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data-ga-action="substance"
|
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data-ga-label="Azo Compounds">
|
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Search in PubMed
|
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</a></li><li><a class="search-in-mesh-link dropdown-block-link"
|
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ref="linksrc=search_in_mesh_link"
|
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href="https://www.ncbi.nlm.nih.gov/mesh?term=%22Azo+Compounds%22"
|
||
data-ga-category="search_mesh"
|
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data-ga-action="substance_link"
|
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data-ga-label="Azo Compounds">
|
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Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
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ref="linksrc=add_to_search_link"
|
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role="button"
|
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data-search-term=""Azo Compounds"[nm]"
|
||
data-ga-category="search"
|
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data-ga-action="add_to_search"
|
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data-ga-label=""Azo Compounds"[nm]"
|
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href="#">
|
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Add to Search
|
||
</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
||
aria-label="Toggle dropdown menu for keyword Pyrimidines"
|
||
tabindex="0"
|
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aria-controls="keyword-actions-substances-1"
|
||
aria-expanded="false"
|
||
data-pinger-ignore>
|
||
Pyrimidines
|
||
</button><div id="keyword-actions-substances-1"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Pyrimidines"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Pyrimidines%22%5Bnm%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Pyrimidines%22%5Bnm%5D&sort=date&sort_order=desc"
|
||
ref="linksrc=search_in_pubmed_keyword_link&keyword="Pyrimidines"[nm]"
|
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data-ga-category="search"
|
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data-ga-action="substance"
|
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data-ga-label="Pyrimidines">
|
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Search in PubMed
|
||
</a></li><li><a class="search-in-mesh-link dropdown-block-link"
|
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ref="linksrc=search_in_mesh_link"
|
||
href="https://www.ncbi.nlm.nih.gov/mesh?term=%22Pyrimidines%22"
|
||
data-ga-category="search_mesh"
|
||
data-ga-action="substance_link"
|
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data-ga-label="Pyrimidines">
|
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Search in MeSH
|
||
</a></li><li><a class="add-to-search-link dropdown-block-link"
|
||
ref="linksrc=add_to_search_link"
|
||
role="button"
|
||
data-search-term=""Pyrimidines"[nm]"
|
||
data-ga-category="search"
|
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data-ga-action="add_to_search"
|
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data-ga-label=""Pyrimidines"[nm]"
|
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href="#">
|
||
Add to Search
|
||
</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
||
aria-label="Toggle dropdown menu for keyword Risdiplam"
|
||
tabindex="0"
|
||
aria-controls="keyword-actions-substances-2"
|
||
aria-expanded="false"
|
||
data-pinger-ignore>
|
||
Risdiplam
|
||
</button><div id="keyword-actions-substances-2"
|
||
class="keyword-actions-dropdown dropdown dropdown-container"
|
||
hidden
|
||
aria-label="Dropdown menu for keyword Risdiplam"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
||
href="/?term=%22Risdiplam%22%5Bnm%5D&sort=date&sort_order=desc"
|
||
data-href="/?term=%22Risdiplam%22%5Bnm%5D&sort=date&sort_order=desc"
|
||
ref="linksrc=search_in_pubmed_keyword_link&keyword="Risdiplam"[nm]"
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