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</a>
|
||
</span>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
|
||
</form>
|
||
|
||
|
||
<div id="article-page-header">
|
||
<div id="article-top-actions-bar" class="article-top-actions-bar">
|
||
<div class="inner-wrap">
|
||
<div class="actions-container">
|
||
<div class="return-to-search">
|
||
|
||
|
||
</div>
|
||
|
||
<div class="multiple-results-actions " role="region" aria-label="save, email, send to">
|
||
<button id="save-results-panel-trigger"
|
||
type="button"
|
||
class="save-results save-results-panel-trigger"
|
||
aria-expanded="false"
|
||
aria-controls="save-action-panel"
|
||
data-ga-category="save_share"
|
||
data-ga-action="save"
|
||
data-ga-label="open">
|
||
Save
|
||
</button><button id="email-results-panel-trigger"
|
||
type="button"
|
||
class="email-results email-results-panel-trigger"
|
||
aria-expanded="false"
|
||
aria-controls="email-action-panel"
|
||
data-ga-category="save_share"
|
||
data-ga-action="email"
|
||
data-ga-label="open">
|
||
Email
|
||
</button><div class="more-actions dropdown-block"><button id="more-actions-trigger"
|
||
type="button"
|
||
class="trigger more-actions-trigger"
|
||
ref="linksrc=show_moreactions_btn"
|
||
aria-label="Send to"
|
||
aria-controls="more-actions-dropdown">Send to</button><div id="more-actions-dropdown" class="dropdown dropdown-container" hidden><div class="content"><ul class="more-actions-links"><li><a class="clipboard-panel-trigger dropdown-block-link "
|
||
href="#"
|
||
role="button"
|
||
data-ga-category="save_share"
|
||
data-ga-action="clipboard"
|
||
data-ga-label="send">
|
||
Clipboard
|
||
</a></li><li><a role="button" class="dropdown-block-link bibliography-trigger-target" href="https://account.ncbi.nlm.nih.gov/?back_url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F32557558%2F%23open-bibliography-panel">My Bibliography</a></li><li><a role="button" class="dropdown-block-link collections-trigger-target" href="https://account.ncbi.nlm.nih.gov/?back_url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F32557558%2F%23open-collections-panel">Collections</a></li><li><a role="button" class="citation-manager-panel-trigger dropdown-block-link citation-manager-trigger-target" href="#">Citation manager</a></li></ul></div></div></div>
|
||
</div>
|
||
|
||
|
||
|
||
<div class="display-options" data-format-key="format"
|
||
data-default-format-value="abstract"
|
||
data-current-format-value="abstract" role="region">
|
||
<button
|
||
class="trigger usa-button"
|
||
title="Change format"
|
||
data-ga-category="display_options"
|
||
data-ga-action="display_options_dialog">
|
||
<span class="button-label">Display options</span>
|
||
</button>
|
||
|
||
<div class="dropdown" hidden>
|
||
<div class="title">
|
||
Display options
|
||
</div>
|
||
|
||
<div class="content">
|
||
|
||
<div class="format-container">
|
||
<span class="option-label">
|
||
Format
|
||
</span>
|
||
<select name="format" data-initial-value="abstract" aria-label="Display format" id="article-display-format">
|
||
<option value="abstract">Abstract</option>
|
||
|
||
<option value="pubmed">PubMed</option>
|
||
|
||
<option value="pmid">PMID</option>
|
||
|
||
</select>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
</div>
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="GNRfOPlHoJFXxe6W3Rgeazjd07UwRFlRXABkrFO3YksrrFcMGaTgEHPRybCIKgTb">
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="article-panels-container" class="article-panels-container">
|
||
<div id="save-action-panel" class="save-action-panel action-panel" aria-hidden="true">
|
||
<div class="inner-wrap">
|
||
<h2 class="action-panel-heading">
|
||
Save citation to file
|
||
</h2>
|
||
<form id="save-action-panel-form"
|
||
class="action-panel-content action-form"
|
||
action="/results-export-ids/"
|
||
data-by-search-action="/results-export-search-data/"
|
||
data-by-ids-action="/results-export-ids/"
|
||
method="post"
|
||
data-by-search-method="post"
|
||
data-by-ids-method="post">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="GNRfOPlHoJFXxe6W3Rgeazjd07UwRFlRXABkrFO3YksrrFcMGaTgEHPRybCIKgTb">
|
||
|
||
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="save-action-format" class="action-panel-label">
|
||
Format:
|
||
</label>
|
||
<select id="save-action-format" name="results-format" class="action-panel-selector">
|
||
<option value="summary-text">Summary (text)</option>
|
||
<option value="pubmed-text">PubMed</option>
|
||
<option value="pmid">PMID</option>
|
||
<option value="abstract">Abstract (text)</option>
|
||
<option value="csv">CSV</option>
|
||
</select>
|
||
</div>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Saving..."
|
||
data-ga-category="save_share"
|
||
data-ga-action="save"
|
||
data-ga-label="save">
|
||
Create file
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Save citations to file' panel"
|
||
ref="linksrc=close_save_panel"
|
||
aria-controls="save-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="save"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div id="email-action-panel"
|
||
class="email-action-panel action-panel"
|
||
aria-hidden="true"
|
||
data-recaptcha-script-url="https://www.recaptcha.net/recaptcha/enterprise.js?render=explicit&onload=onloadCaptchaCallback"
|
||
data-recaptcha-enabled="true">
|
||
<div class="inner-wrap">
|
||
<h2 class="action-panel-heading">
|
||
Email citation
|
||
</h2>
|
||
<form id="email-action-panel-form"
|
||
class="action-panel-content action-form"
|
||
action="/send-email/"
|
||
data-by-search-action="/results-export-email-by-search-data/"
|
||
data-by-ids-action="/send-email/"
|
||
data-by-search-method="post"
|
||
data-by-ids-method="post"
|
||
method="post"
|
||
>
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="GNRfOPlHoJFXxe6W3Rgeazjd07UwRFlRXABkrFO3YksrrFcMGaTgEHPRybCIKgTb">
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<span class="action-panel-label">
|
||
Subject:
|
||
</span>
|
||
<span class="email-subject" id="email-subject" aria-label="Email subject">1 selected item: 32557558 - PubMed</span>
|
||
<input type="hidden" name="email-subject" value="1 selected item: 32557558"/>
|
||
<input type="hidden" name="email-subject-hash" value="cea87d69b7929dd4aa38430e184f63b967936d3cae8929aec59339c73fe2440a"/>
|
||
</div>
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="email-to" class="action-panel-label required-field-asterisk">
|
||
To:
|
||
</label>
|
||
<input type="email" aria-label="Recipient Email Address" placeholder="email@example.com" id="email-to" class="email-to" pattern="^[a-zA-Z0-9_.+-]+@[a-zA-Z0-9-]+\.[a-zA-Z0-9-.]+$" maxlength="100" required>
|
||
</div>
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="email-from" class="action-panel-label">
|
||
From:
|
||
</label>
|
||
<input type="email" aria-label="Sender Email Address" placeholder="email@example.com" id="email-from" class="email-from" pattern="^[a-zA-Z0-9_.+-]+@[a-zA-Z0-9-]+\.[a-zA-Z0-9-.]+$" maxlength="256">
|
||
</div>
|
||
|
||
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="email-citation-format" class="action-panel-label">
|
||
Format:
|
||
</label>
|
||
<select id="email-citation-format" name="citation-format" class="action-panel-selector email-citation-format">
|
||
<option selected="selected" value="summary">Summary</option>
|
||
<option value="summary-text">Summary (text)</option>
|
||
<option value="abstract">Abstract</option>
|
||
<option value="abstract-text">Abstract (text)</option>
|
||
|
||
</select>
|
||
</div>
|
||
<div class="include-supplemental-container">
|
||
<input type="checkbox" aria-label="Include MeSH and other data" name="include-supplemental" id="email-include-supplemental" class="email-include-supplemental">
|
||
<label for="email-include-supplemental" class="email-include-supplemental-label">MeSH and other data</label>
|
||
</div>
|
||
|
||
|
||
|
||
<div class="form-field recaptcha ">
|
||
|
||
|
||
|
||
<div class="g-recaptcha" id="id-recaptcha" data-sitekey="6LfsWHMdAAAAAClKbtOpjQ2pMjgsGxvv7NdZW9uI"></div>
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
<div id="captcha-error-message" class="usa-input-error-message captcha-validation-message" role="alert"></div>
|
||
|
||
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Sending..."
|
||
data-ga-category="save_share"
|
||
data-ga-action="email"
|
||
data-ga-label="send">
|
||
Send email
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Email citations' panel"
|
||
ref="linksrc=close_email_panel"
|
||
aria-controls="email-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="email"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
<input type="hidden" name="email-search-details" value="" />
|
||
<input type="hidden" name="email-search-details-hash" value="0e42663a6c3bd85498fcb88798998fed7bfdc45d457db35281e41afe13cc0524" />
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="collections-action-panel"
|
||
class="collections-action-panel action-panel in-progress-dots-panel"
|
||
aria-hidden="true"
|
||
data-collections-open-panel-enabled="false"
|
||
data-collections-open-panel-url-hash="#open-collections-panel">
|
||
<div class="inner-wrap">
|
||
<h3 class="action-panel-heading">
|
||
Add to Collections
|
||
</h3>
|
||
|
||
|
||
<form id="collections-action-panel-form"
|
||
class="collections-action-panel-form action-panel-content action-form action-panel-smaller-selectors"
|
||
data-existing-collections-url="/list-existing-collections/"
|
||
data-add-to-existing-collection-url="/add-to-existing-collection/"
|
||
data-create-and-add-to-new-collection-url="/create-and-add-to-new-collection/"
|
||
data-get-article-ids-by-search-url="/get-article-ids-by-search/"
|
||
data-myncbi-max-collection-name-length="100"
|
||
data-add-to-collection-max-amount="1000"
|
||
data-collections-root-url="https://www.ncbi.nlm.nih.gov/myncbi/collections/">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="GNRfOPlHoJFXxe6W3Rgeazjd07UwRFlRXABkrFO3YksrrFcMGaTgEHPRybCIKgTb">
|
||
|
||
|
||
|
||
<div class="choice-group" role="radiogroup">
|
||
<ul class="radio-group-items">
|
||
<li>
|
||
<input type="radio"
|
||
id="collections-action-panel-new"
|
||
class="collections-new"
|
||
name="collections"
|
||
value="new"
|
||
data-ga-category="save_share"
|
||
data-ga-action="collections"
|
||
data-ga-label="collections_radio_new">
|
||
<label for="collections-action-panel-new">Create a new collection</label>
|
||
</li>
|
||
<li>
|
||
<input type="radio"
|
||
id="collections-action-panel-existing"
|
||
class="collections-existing"
|
||
name="collections"
|
||
value="existing"
|
||
checked="true"
|
||
data-ga-category="save_share"
|
||
data-ga-action="collections"
|
||
data-ga-label="collections_radio_existing">
|
||
<label for="collections-action-panel-existing">Add to an existing collection</label>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
|
||
<div class="controls-wrapper">
|
||
<div class="action-panel-control-wrap new-collections-controls">
|
||
<label for="collections-action-panel-add-to-new" class="action-panel-label required-field-asterisk">
|
||
Name your collection:
|
||
</label>
|
||
<input
|
||
type="text"
|
||
name="add-to-new-collection"
|
||
id="collections-action-panel-add-to-new"
|
||
class="collections-action-add-to-new"
|
||
pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/"
|
||
maxlength="100"
|
||
data-ga-category="save_share"
|
||
data-ga-action="create_collection"
|
||
data-ga-label="non_favorties_collection">
|
||
<div class="collections-new-name-too-long usa-input-error-message selection-validation-message">
|
||
Name must be less than 100 characters
|
||
</div>
|
||
</div>
|
||
<div class="action-panel-control-wrap existing-collections-controls">
|
||
<label for="collections-action-panel-add-to-existing" class="action-panel-label">
|
||
Choose a collection:
|
||
</label>
|
||
<select id="collections-action-panel-add-to-existing"
|
||
class="action-panel-selector collections-action-add-to-existing"
|
||
data-ga-category="save_share"
|
||
data-ga-action="select_collection"
|
||
data-ga-label="($('#collections-action-add-to-existing').val() === 'Favorites') ? 'Favorites' : 'non_favorites_collection'">
|
||
</select>
|
||
<div class="collections-retry-load-on-error usa-input-error-message selection-validation-message">
|
||
Unable to load your collection due to an error<br>
|
||
<a href="#">Please try again</a>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Adding..."
|
||
data-pinger-ignore
|
||
data-ga-category="save_share"
|
||
data-ga-action="collections"
|
||
data-ga-label="add">
|
||
Add
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Add to Collections' panel"
|
||
ref="linksrc=close_collections_panel"
|
||
aria-controls="collections-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="collections"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="bibliography-action-panel"
|
||
class="bibliography-action-panel action-panel in-progress-dots-panel"
|
||
aria-hidden="true"
|
||
data-bibliography-open-panel-enabled="false"
|
||
data-bibliography-open-panel-url-hash="#open-bibliography-panel">
|
||
<div class="inner-wrap">
|
||
<h3 class="action-panel-heading">
|
||
Add to My Bibliography
|
||
</h3>
|
||
<form id="bibliography-action-panel-form"
|
||
class="bibliography-action-panel-form action-panel-content action-form action-panel-smaller-selectors"
|
||
data-add-to-bibliography-max-amount="100"
|
||
data-add-to-bibliography-batch-size="10"
|
||
data-bibliography-delegates-url="/list-bibliography-delegates/"
|
||
data-add-to-bibliography-url="/add-to-bibliography/"
|
||
data-get-article-ids-by-search-url="/get-article-ids-by-search/"
|
||
data-mybib-root-url="https://www.ncbi.nlm.nih.gov/myncbi/collections/mybibliography/">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="GNRfOPlHoJFXxe6W3Rgeazjd07UwRFlRXABkrFO3YksrrFcMGaTgEHPRybCIKgTb">
|
||
|
||
|
||
|
||
<div class="action-panel-control-wrap bibliographies-controls">
|
||
<div class="choice-group">
|
||
<ul class="bibliographies-action-add radio-group-items">
|
||
<li>
|
||
<input name="bibliography" id="my-bibliography" class="my-bibliography" type="radio" checked/>
|
||
<label for="my-bibliography">My Bibliography</label>
|
||
</li>
|
||
</ul>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="bibliographies-retry-load-on-error usa-input-error-message selection-validation-message">
|
||
Unable to load your delegates due to an error<br>
|
||
<a href="#">Please try again</a>
|
||
</div>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Adding..."
|
||
data-pinger-ignore>
|
||
Add
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Add to bibliography' panel"
|
||
ref="linksrc=close_bibliography_panel"
|
||
aria-controls="bibliography-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="mybib"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div id="saved-search-action-panel" class="saved-search-action-panel action-panel " aria-hidden="true"
|
||
data-saved-search-open-panel-enabled="false"
|
||
data-saved-search-open-panel-url-hash="#open-saved-search-panel">
|
||
<div class="inner-wrap">
|
||
<h2 class="action-panel-heading">
|
||
Your saved search
|
||
</h2>
|
||
|
||
<form id="saved-search-action-panel-form"
|
||
class="saved-search-action-panel-form action-panel-content action-form"
|
||
data-create-saved-search-url="/create-saved-search/"
|
||
data-try-search-terms-url="/try-search-term/"
|
||
data-saved-search-root-url="https://www.ncbi.nlm.nih.gov/myncbi/searches/">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="GNRfOPlHoJFXxe6W3Rgeazjd07UwRFlRXABkrFO3YksrrFcMGaTgEHPRybCIKgTb">
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="saved-search-name" class="action-panel-label saved-search-name-label required-field-asterisk">
|
||
Name of saved search:
|
||
</label>
|
||
<input maxlength="200"
|
||
type="text"
|
||
name="saved-search-name"
|
||
id="saved-search-name"
|
||
class="saved-search-name"
|
||
value=""
|
||
required
|
||
pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/">
|
||
</div>
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="saved-search-term" class="action-panel-label required-field-asterisk">
|
||
Search terms:
|
||
</label>
|
||
<textarea name="saved-search-term" id="saved-search-term" class="saved-search-term" required></textarea>
|
||
</div>
|
||
<div class="test-search-term-wrap">
|
||
<a href="#" class="try-search-term">Test search terms</a>
|
||
</div>
|
||
<div class="choice-group action-panel-extra-margin-top">
|
||
<span class="action-panel-label" id="fieldset-label">
|
||
Would you like email updates of new search results?
|
||
</span>
|
||
<fieldset id="saved-search-alert" aria-describedby="fieldset-label">
|
||
<legend class="usa-sr-only">Saved Search Alert Radio Buttons</legend>
|
||
<ul class="radio-group-items">
|
||
<li>
|
||
<input type="radio" id="saved-search-alert-yes" class="saved-search-alert-yes" name="saved-search-alert" value="yes" checked>
|
||
<label for="saved-search-alert-yes" class="action-panel-label">Yes</label>
|
||
</li>
|
||
<li>
|
||
<input aria-label="No radio input" type="radio" id="saved-search-alert-no" class="saved-search-alert-no" name="saved-search-alert" value="no">
|
||
<label for="saved-search-alert-no" class="action-panel-label">No</label>
|
||
</li>
|
||
</ul>
|
||
</fieldset>
|
||
</div>
|
||
|
||
<div class="alert-schedule-wrap">
|
||
<div class="action-panel-control-wrap">
|
||
<label class="action-panel-label">
|
||
Email:
|
||
</label>
|
||
<span aria-label="Email address" id="saved-search-email" class="action-panel-label"><span class="action-panel-label-bold"></span> (<a class="myncbi-account-settings" href="https://www.ncbi.nlm.nih.gov/account/settings/">change</a>)</span>
|
||
</div>
|
||
<div class="action-panel-control-wrap action-panel-extra-margin-top">
|
||
<label for="saved-search-frequency" class="action-panel-label">
|
||
Frequency:
|
||
</label>
|
||
<select id="saved-search-frequency" class="no-border-panel-selector saved-search-frequency">
|
||
<option value="monthly">Monthly</option>
|
||
<option value="weekly">Weekly</option>
|
||
<option value="daily">Daily</option>
|
||
</select>
|
||
</div>
|
||
<div class="action-panel-control-wrap saved-search-monthly-additional">
|
||
<label for="saved-search-monthly-on-day" class="action-panel-label">
|
||
Which day?
|
||
</label>
|
||
<select id="saved-search-monthly-on-day" class="no-border-panel-selector">
|
||
<option value="Sunday">The first Sunday</option>
|
||
<option value="Monday">The first Monday</option>
|
||
<option value="Tuesday">The first Tuesday</option>
|
||
<option value="Wednesday">The first Wednesday</option>
|
||
<option value="Thursday">The first Thursday</option>
|
||
<option value="Friday">The first Friday</option>
|
||
<option value="Saturday">The first Saturday</option>
|
||
<option value="day">The first day</option>
|
||
<option value="weekday">The first weekday</option>
|
||
</select>
|
||
</div>
|
||
<div class="action-panel-control-wrap saved-search-weekly-additional">
|
||
<label for="saved-search-weekly-on-day" class="action-panel-label">
|
||
Which day?
|
||
</label>
|
||
<select id="saved-search-weekly-on-day" class="no-border-panel-selector saved-search-weekly-on-day">
|
||
<option value="Sunday">Sunday</option>
|
||
<option value="Monday">Monday</option>
|
||
<option value="Tuesday">Tuesday</option>
|
||
<option value="Wednesday">Wednesday</option>
|
||
<option value="Thursday">Thursday</option>
|
||
<option value="Friday">Friday</option>
|
||
<option value="Saturday">Saturday</option>
|
||
</select>
|
||
</div>
|
||
<div class="action-panel-control-wrap">
|
||
<label for="saved-search-report" class="action-panel-label">
|
||
Report format:
|
||
</label>
|
||
<select id="saved-search-report" class="no-border-panel-selector saved-search-report">
|
||
<option value="DocSum">Summary</option>
|
||
<option value="DocSumText">Summary (text)</option>
|
||
<option value="Abstract">Abstract</option>
|
||
<option value="AbstractText">Abstract (text)</option>
|
||
<option value="MEDLINE">PubMed</option>
|
||
</select>
|
||
</div>
|
||
<div class="action-panel-control-wrap">
|
||
<label for="saved-search-amount" class="action-panel-label">
|
||
Send at most:
|
||
</label>
|
||
<select id="saved-search-amount" class="no-border-panel-selector saved-search-amount">
|
||
<option value="1">1 item</option>
|
||
<option value="5" selected>5 items</option>
|
||
<option value="10">10 items</option>
|
||
<option value="20">20 items</option>
|
||
<option value="50">50 items</option>
|
||
<option value="100">100 items</option>
|
||
<option value="200">200 items</option>
|
||
</select>
|
||
</div>
|
||
<div>
|
||
<input type="checkbox" id="saved-search-send-if-no-result" class="saved-search-send-if-no-result" name="saved-search-send-if-no-result">
|
||
<label for="saved-search-send-if-no-result" class="action-panel-label smaller-checkbox">
|
||
Send even when there aren't any new results
|
||
</label>
|
||
</div>
|
||
<div class="action-panel-control-wrap option-text-in-email-wrap">
|
||
<label for="saved-search-email-text" class="action-panel-label">
|
||
Optional text in email:
|
||
</label>
|
||
<textarea name="saved-search-email-text"
|
||
id="saved-search-email-text"
|
||
class="saved-search-email-text"></textarea>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Saving..."
|
||
data-ga-category="save_share"
|
||
data-ga-action="alert"
|
||
data-ga-label="save">
|
||
Save
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Your saved search' panel"
|
||
ref="linksrc=close_saved_search_panel"
|
||
aria-controls="saved-search-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="alert"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
<div id="citation-manager-action-panel" class="citation-manager-action-panel action-panel" aria-hidden="true">
|
||
<div class="inner-wrap">
|
||
<h2 class="action-panel-heading">
|
||
Create a file for external citation management software
|
||
</h2>
|
||
<form id="citation-manager-action-panel-form"
|
||
class="action-panel-content action-form"
|
||
action="/results-export-ids/"
|
||
data-by-search-action="/results-export-search-data/"
|
||
data-by-ids-action="/results-export-ids/"
|
||
method="post"
|
||
data-by-search-method="post"
|
||
data-by-ids-method="post">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="GNRfOPlHoJFXxe6W3Rgeazjd07UwRFlRXABkrFO3YksrrFcMGaTgEHPRybCIKgTb">
|
||
|
||
|
||
|
||
<input name="results-format" type="hidden" value="pubmed"/>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Sending..."
|
||
data-ga-category="save_share"
|
||
data-ga-action="citation_manager"
|
||
data-ga-label="save">
|
||
Create file
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Send citations to citation manager' panel"
|
||
ref="linksrc=close_citation_manager_panel"
|
||
aria-controls="citation-manager-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="citation_manager"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div id="rss-action-panel" class="rss-action-panel action-panel " aria-hidden="true">
|
||
<div class="inner-wrap">
|
||
<h2 class="action-panel-heading">
|
||
Your RSS Feed
|
||
</h2>
|
||
|
||
<form id="rss-action-panel-form"
|
||
class="rss-action-panel-form action-panel-content action-form"
|
||
data-create-rss-feed-url="/create-rss-feed-url/"
|
||
data-search-form-term-value="">
|
||
|
||
<input type="hidden" name="csrfmiddlewaretoken" value="GNRfOPlHoJFXxe6W3Rgeazjd07UwRFlRXABkrFO3YksrrFcMGaTgEHPRybCIKgTb">
|
||
|
||
<div class="action-panel-control-wrap">
|
||
<label for="rss-name" class="action-panel-label required-field-asterisk">
|
||
Name of RSS Feed:
|
||
</label>
|
||
<input maxlength="200"
|
||
placeholder="Name"
|
||
type="text"
|
||
name="rss-name"
|
||
id="rss-name"
|
||
class="rss-name"
|
||
value=''
|
||
required
|
||
pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/">
|
||
</div>
|
||
|
||
<div class="rss-limit-wrap">
|
||
<div class="action-panel-control-wrap action-panel-extra-margin-top">
|
||
<label for="rss-limit" class="action-panel-label">
|
||
Number of items displayed:
|
||
</label>
|
||
<select id="rss-limit" class="no-border-panel-selector rss-limit">
|
||
<option value="5">5</option>
|
||
<option value="10">10</option>
|
||
<option value="15" selected="selected">15</option>
|
||
<option value="20">20</option>
|
||
<option value="50">50</option>
|
||
<option value="100">100</option>
|
||
</select>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="action-panel-actions">
|
||
<button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Creating..."
|
||
data-ga-category="save_share"
|
||
data-ga-action="alert"
|
||
data-ga-label="save">
|
||
Create RSS
|
||
</button>
|
||
<button class="action-panel-cancel"
|
||
aria-label="Close 'Your RSS' panel"
|
||
ref="linksrc=close_rss_panel"
|
||
aria-controls="rss-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="save_share"
|
||
data-ga-action="alert"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button>
|
||
</div>
|
||
|
||
<div class="action-panel-control-wrap rss-link-copy-wrap">
|
||
<label for="rss-link" class="usa-sr-only">RSS Link</label>
|
||
<input placeholder="Your RSS Feed Link" type="text" name="rss-link" id="rss-link" class="rss-link" title="RSS Link">
|
||
<button
|
||
type="button"
|
||
disabled
|
||
class="rss-link-copy-button disabled"
|
||
data-ga-category="save_share"
|
||
data-ga-action="rss"
|
||
data-ga-label="copy">
|
||
Copy
|
||
</button>
|
||
</div>
|
||
</form>
|
||
</div>
|
||
</div>
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="article-page" id="article-page" data-article-pmid="32557558">
|
||
<aside class="page-sidebar">
|
||
<div class="inner-wrap">
|
||
|
||
<div class="full-text-links">
|
||
<div class="full-view">
|
||
<h3 class="title">
|
||
Full text links
|
||
</h3>
|
||
<div class="full-text-links-list">
|
||
<a class="link-item
|
||
|
||
dialog-focus"
|
||
href="https://doi.org/10.1002/14651858.CD013001.pub2"
|
||
target="_blank"
|
||
rel="noopener"
|
||
|
||
ref="linksrc=fulltextorjournal_fulltext&is_pmc=False&PrId=3058&itool=Abstract-def&log$=linkouticon&uid=32557558&db=pubmed&nlmid=100909747"
|
||
title="See full text options at Wiley"
|
||
|
||
data-ga-category="full_text"
|
||
data-ga-action="Wiley"
|
||
data-ga-label="32557558"
|
||
><img src="https://cdn.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--media.wiley.com-assets-7331-42-Cochrane_Library_Logo_RGB_120x30.jpg" alt="Wiley full text link"><span class="text">
|
||
|
||
Wiley
|
||
|
||
</span></a><a class="link-item
|
||
pmc
|
||
"
|
||
href="https://pmc.ncbi.nlm.nih.gov/articles/pmid/32557558/"
|
||
target="_blank"
|
||
rel="noopener"
|
||
|
||
ref="linksrc=fulltextorjournal_fulltext&is_pmc=True&PrId=3494&itool=Abstract-def&log$=linkouticon&uid=32557558&db=pubmed&nlmid=100909747"
|
||
title="Free full text at PubMed Central"
|
||
|
||
data-ga-category="full_text"
|
||
data-ga-action="PMC"
|
||
data-ga-label="32557558"
|
||
><span class="text">
|
||
|
||
Free PMC article
|
||
|
||
</span></a>
|
||
</div>
|
||
|
||
</div>
|
||
|
||
<div class="short-view">
|
||
<a href="#" class="full-text-links-button full-text-links-dialog-trigger">
|
||
Full text links
|
||
</a>
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
<div class="actions-buttons sidebar"><h3 class="title">Actions</h3><div class="inner-wrap"><button class="citation-button citation-dialog-trigger"
|
||
aria-label="Open dialog with citation text in different styles"
|
||
data-ga-category="save_share"
|
||
data-ga-action="cite"
|
||
data-ga-label="open"
|
||
data-all-citations-url="/32557558/citations/"
|
||
data-citation-style="nlm"
|
||
data-pubmed-format-link="/32557558/export/"><span class="button-label">Cite</span></button><link type="text/css" href="ncbi-overlay-block/src/overlay-block.css"><div class="collections-button-container" data-article-id="32557558" data-article-db="pubmed"><button class="collections-button collections-dialog-trigger"
|
||
aria-label="Save article in MyNCBI collections."
|
||
data-ga-category="collections_button"
|
||
data-ga-action="click"
|
||
data-ga-label="collections_button"
|
||
data-collections-open-dialog-enabled="false"
|
||
data-collections-open-dialog-url="https://account.ncbi.nlm.nih.gov/?back_url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F32557558%2F%23open-collections-dialog"
|
||
data-in-collections="false"><span class="button-label">Collections</span></button><div class="overlay" role="dialog"><div id="collections-action-dialog"
|
||
class="dialog collections-dialog"
|
||
aria-hidden="true"><div class="title">Add to Collections</div><div class="collections-action-panel action-panel"><form id="collections-action-dialog-form"
|
||
class="collections-action-panel-form action-panel-content action-form action-panel-smaller-selectors"
|
||
data-existing-collections-url="/list-existing-collections/"
|
||
data-add-to-existing-collection-url="/add-to-existing-collection/"
|
||
data-create-and-add-to-new-collection-url="/create-and-add-to-new-collection/"
|
||
data-myncbi-max-collection-name-length="100"
|
||
data-collections-root-url="https://www.ncbi.nlm.nih.gov/myncbi/collections/"><input type="hidden" name="csrfmiddlewaretoken" value="GNRfOPlHoJFXxe6W3Rgeazjd07UwRFlRXABkrFO3YksrrFcMGaTgEHPRybCIKgTb"><div class="choice-group" role="radiogroup"><ul class="radio-group-items"><li><input type="radio"
|
||
id="collections-action-dialog-new"
|
||
class="collections-new"
|
||
name="collections"
|
||
value="new"
|
||
data-ga-category="collections_button"
|
||
data-ga-action="click"
|
||
data-ga-label="collections_radio_new"><label for="collections-action-dialog-new">Create a new collection</label></li><li><input type="radio"
|
||
id="collections-action-dialog-existing"
|
||
class="collections-existing"
|
||
name="collections"
|
||
value="existing"
|
||
checked="true"
|
||
data-ga-category="collections_button"
|
||
data-ga-action="click"
|
||
data-ga-label="collections_radio_existing"><label for="collections-action-dialog-existing">Add to an existing collection</label></li></ul></div><div class="controls-wrapper"><div class="action-panel-control-wrap new-collections-controls"><label for="collections-action-dialog-add-to-new" class="action-panel-label required-field-asterisk">
|
||
Name your collection:
|
||
</label><input
|
||
type="text"
|
||
name="add-to-new-collection"
|
||
id="collections-action-dialog-add-to-new"
|
||
class="collections-action-add-to-new"
|
||
pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/"
|
||
maxlength="100"
|
||
data-ga-category="collections_button"
|
||
data-ga-action="create_collection"
|
||
data-ga-label="non_favorties_collection"><div class="collections-new-name-too-long usa-input-error-message selection-validation-message">
|
||
Name must be less than 100 characters
|
||
</div></div><div class="action-panel-control-wrap existing-collections-controls"><label for="collections-action-dialog-add-to-existing" class="action-panel-label">
|
||
Choose a collection:
|
||
</label><select id="collections-action-dialog-add-to-existing"
|
||
class="action-panel-selector collections-action-add-to-existing"
|
||
data-ga-category="collections_button"
|
||
data-ga-action="select_collection"
|
||
data-ga-label="($('.collections-action-add-to-existing').val() === 'Favorites') ? 'Favorites' : 'non_favorites_collection'"></select><div class="collections-retry-load-on-error usa-input-error-message selection-validation-message">
|
||
Unable to load your collection due to an error<br><a href="#">Please try again</a></div></div></div><div class="action-panel-actions"><button class="action-panel-submit"
|
||
type="submit"
|
||
data-loading-label="Adding..."
|
||
data-pinger-ignore
|
||
data-ga-category="collections_button"
|
||
data-ga-action="click"
|
||
data-ga-label="add">
|
||
Add
|
||
</button><button class="action-panel-cancel"
|
||
aria-label="Close 'Add to Collections' panel"
|
||
ref="linksrc=close_collections_panel"
|
||
aria-controls="collections-action-panel"
|
||
aria-expanded="false"
|
||
data-ga-category="collections_button"
|
||
data-ga-action="click"
|
||
data-ga-label="cancel">
|
||
Cancel
|
||
</button></div></form></div></div></div></div><button class="more-actions-button more-actions-dialog-trigger"
|
||
title="Open dialog with more actions to take"
|
||
ref="linksrc=more_actions_btn"></button><div class="display-options" data-format-key="format"
|
||
data-default-format-value="abstract"
|
||
data-current-format-value="abstract" role="region"><button
|
||
class="trigger usa-button"
|
||
title="Change format"
|
||
data-ga-category="display_options"
|
||
data-ga-action="display_options_dialog"><span class="button-label">Display options</span></button><div class="dropdown" hidden><div class="title">
|
||
Display options
|
||
</div><div class="content"><div class="format-container"><span class="option-label">
|
||
Format
|
||
</span><select name="format" data-initial-value="abstract" aria-label="Display format" id="sidebar-actions-display-format"><option value="abstract">Abstract</option><option value="pubmed">PubMed</option><option value="pmid">PMID</option></select></div></div></div></div></div></div>
|
||
|
||
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</a></li></ul></div></div></div><span class="period">. </span><span class="cit">2020 Jun 17;6(6):CD013001.</span>
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<h1 class="heading-title">
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Corneal collagen cross-linking for bacterial infectious keratitis
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</h1>
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<div class="publication-type" >Meta-Analysis</div>
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<h1 class="heading-title">
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Corneal collagen cross-linking for bacterial infectious keratitis
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</a></li></ul></div></div></div><span class="period">. </span><span class="cit">2020 Jun 17;6(6):CD013001.</span>
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Background:
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Infectious keratitis is an infection of the cornea that can be caused by bacteria, viruses, fungi, protozoa, or parasites. It may be associated with ocular surgery, trauma, contact lens wear, or conditions that cause deficiency or loss of corneal sensation, or suppression of the immune system, such as diabetes, chronic use of topical steroids, or immunomodulatory therapies. Photoactivated chromophore for collagen cross-linking (PACK-CXL) of the cornea is a therapy that has been successful in treating eye conditions such as keratoconus and corneal ectasia. More recently, PACK-CXL has been explored as a treatment option for infectious keratitis.
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Objectives:
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To determine the comparative effectiveness and safety of PACK-CXL with standard therapy versus standard therapy alone for the treatment of bacterial keratitis.
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We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (which contains the Cochrane Eyes and Vision Trials Register) (2019, Issue 7); Ovid MEDLINE; Embase.com; PubMed; Latin American and Caribbean Health Science Information database (LILACS); ClinicalTrials.gov; and the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP). We did not use any date or language restrictions in the electronic search for trials. We last searched the electronic databases on 8 July 2019.
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Selection criteria:
|
||
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|
||
We included randomized controlled trials (RCTs), quasi-RCTs, and controlled clinical trials (CCTs) of PACK-CXL for bacterial keratitis. We included quasi-RCTs and CCTs as we anticipated that there would not be many RCTs eligible for inclusion.
|
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Data collection and analysis:
|
||
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|
||
|
||
Two review authors working independently selected studies for inclusion in the review, assessed trials for risk of bias, and extracted data. The primary outcome was proportion of participants with complete healing at four to eight weeks. Secondary outcomes included visual acuity, morphology, adverse events, and treatment failure at four to eight weeks.
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<strong class="sub-title">
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Main results:
|
||
</strong>
|
||
|
||
We included three trials (two RCTs and one quasi-RCT) in this review for a total of 59 participants (59 eyes) with bacterial keratitis. Trials were all single-center and were conducted in Egypt, Iran, and Thailand between 2010 and 2014. It is very uncertain whether PACK-CXL with standard antibiotic therapy is more effective than standard antibiotic therapy alone for re-epithelialization and complete healing (risk ratio (RR) 1.53, 95% confidence interval (CI) 0.88 to 2.66; participants = 15). We judged the certainty of the evidence to be very low due to the small sample size and high risk of selection and performance bias. The high risk of selection bias reflects the overall review. Masking of participants was not possible for the surgical arm. No participant had a best-corrected visual acuity of 20/100 or better at eight weeks (very low certainty evidence). There is also no evidence that use of PACK-CXL with standard therapy results in fewer instances of treatment failure than standard therapy alone (RR 0.50, 95% CI 0.05 to 4.98; participants = 32). We judged the certainty of evidence to be low due to the small sample size and high risk of selection bias. There were no adverse events reported at 14 days (low certainty evidence). Data on other outcomes, such as visual acuity and morphological characteristics, could not be compared because of variable time points and specific metrics.
|
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</p>
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||
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||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<p>
|
||
|
||
<strong class="sub-title">
|
||
Authors' conclusions:
|
||
</strong>
|
||
|
||
The current evidence on the effectiveness of PACK-CXL for bacterial keratitis is of low certainty and clinically heterogenous in regard to outcomes. There are five ongoing RCTs enrolling 1136 participants that may provide better answers in the next update of this review. Any future research should include subgroup analyses based on etiology. A core outcomes set would benefit healthcare decision-makers in comparing and understanding study data.
|
||
</p>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<p>
|
||
|
||
<strong class="sub-title">
|
||
Trial registration:
|
||
</strong>
|
||
|
||
ClinicalTrials.gov <a href="http://clinicaltrials.gov/show/NCT01831206" title="See in ClinicalTrials.gov">NCT01831206</a> <a href="http://clinicaltrials.gov/show/NCT01464268" title="See in ClinicalTrials.gov">NCT01464268</a> <a href="http://clinicaltrials.gov/show/NCT02349165" title="See in ClinicalTrials.gov">NCT02349165</a> <a href="http://clinicaltrials.gov/show/NCT02863809" title="See in ClinicalTrials.gov">NCT02863809</a> <a href="http://clinicaltrials.gov/show/NCT03041883" title="See in ClinicalTrials.gov">NCT03041883</a> <a href="http://clinicaltrials.gov/show/NCT03138785" title="See in ClinicalTrials.gov">NCT03138785</a> <a href="http://clinicaltrials.gov/show/NCT00912509" title="See in ClinicalTrials.gov">NCT00912509</a> <a href="http://clinicaltrials.gov/show/NCT02328053" title="See in ClinicalTrials.gov">NCT02328053</a> <a href="http://clinicaltrials.gov/show/NCT02088970" title="See in ClinicalTrials.gov">NCT02088970</a> <a href="http://clinicaltrials.gov/show/NCT02865876" title="See in ClinicalTrials.gov">NCT02865876</a> <a href="http://clinicaltrials.gov/show/NCT02570321" title="See in ClinicalTrials.gov">NCT02570321</a> <a href="http://clinicaltrials.gov/show/NCT02717871" title="See in ClinicalTrials.gov">NCT02717871</a>.
|
||
</p>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<p class="copyright" id="copyright">
|
||
Copyright © 2020 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
|
||
</p>
|
||
|
||
|
||
<p class="disclaimer" id="disclaimer">
|
||
<a href="/disclaimer/" target="_blank" data-ga-category="literature_resources"
|
||
data-ga-action="disclaimer_link" data-ga-label="under_abstract">PubMed Disclaimer</a>
|
||
</p>
|
||
|
||
<div class="conflict-of-interest" id="conflict-of-interest">
|
||
<h2 class="title">
|
||
Conflict of interest statement
|
||
</h2>
|
||
|
||
<div class="statement">
|
||
|
||
|
||
|
||
<p xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:p1="http://pubmed.gov/pub-one">RB: Dr Bovelle has within the past three years received speaker fees from Allergan, which are unrelated to this work. SAD: none GH: none JK: none</p>
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="figures" id="figures">
|
||
<h2 class="title">
|
||
Figures
|
||
</h2>
|
||
|
||
<div class="figures-list" id="slides-container"
|
||
itemscope itemtype="http://schema.org/ImageGallery">
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<figure class="figure-item "
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itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="0"
|
||
data-label-slug="1">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fbf/7389372/195ee7e69cd5/nCD013001-FIG-01.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-0"
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||
role="button"
|
||
data-image-width="635"
|
||
data-image-height="509"
|
||
data-image-alt="1"
|
||
data-pmc-id="PMC7389372"
|
||
data-figure-id="CD013001-fig-0001">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-0"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fbf/7389372/b9c9008e4fd9/nCD013001-FIG-01.gif"
|
||
alt="1" />
|
||
</a>
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||
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||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="635">
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<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
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<div class="caption-wrap">
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||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 1 </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Study flow diagram. </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
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||
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||
|
||
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||
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||
<strong class="figure-label">
|
||
<p> 1 </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Study flow diagram. </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-0" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
1
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Study flow diagram.</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
<figure class="figure-item "
|
||
itemscope itemtype="http://schema.org/ImageObject"
|
||
itemprop="associatedMedia"
|
||
data-slide-index="1"
|
||
data-label-slug="2">
|
||
<a class="figure-link"
|
||
href="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fbf/7389372/6dc27623ee91/tCD013001-FIG-02.jpg"
|
||
itemprop="contentUrl"
|
||
aria-describedby="figure-caption-1"
|
||
role="button"
|
||
data-image-width="100"
|
||
data-image-height="100"
|
||
data-image-alt="2"
|
||
data-pmc-id="PMC7389372"
|
||
data-figure-id="CD013001-fig-0002">
|
||
<img class="figure-thumb" itemprop="thumbnail"
|
||
id="article-image-1"
|
||
src="https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fbf/7389372/d14c55c67933/tCD013001-FIG-02.gif"
|
||
alt="2" />
|
||
</a>
|
||
|
||
<meta itemprop="width" itemtype="http://schema.org/ImageObject" content="100">
|
||
<meta itemprop="height" itemtype="http://schema.org/ImageObject" content="100">
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||
|
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|
||
<div class="figure-caption figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="caption" aria-hidden="true">
|
||
|
||
<div class="caption-wrap">
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 2 </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Risk of bias summary: review authors'… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
</div>
|
||
|
||
<div class="figure-caption-medium figure-caption-text" aria-hidden="true">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
<p> 2 </p>
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents"><p> Risk of bias summary: review authors' judgements about each risk of bias item for… </p></div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
<figcaption id="figure-caption-1" class="figure-caption-full figure-caption-text" itemtype="http://schema.org/ImageObject" itemprop="description">
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<strong class="figure-label">
|
||
2
|
||
</strong>
|
||
|
||
|
||
|
||
<div class="figure-caption-contents">Risk of bias summary: review authors' judgements about each risk of bias item for each included study.</div>
|
||
|
||
|
||
|
||
|
||
</figcaption>
|
||
|
||
|
||
</figure>
|
||
|
||
</div>
|
||
|
||
|
||
|
||
<!-- Root element of PhotoSwipe. Must have class pswp. -->
|
||
<div class="pswp figures-dialog" id="figures-dialog" tabindex="-1" role="dialog" aria-hidden="true"
|
||
data-image-gallery-uid="article-figures" aria-label="Figures Dialog">
|
||
<!-- Background of PhotoSwipe.
|
||
It's a separate element as animating opacity is faster than rgba(). -->
|
||
<div class="pswp__bg"></div>
|
||
|
||
<!-- Slides wrapper with overflow:hidden. -->
|
||
<div class="pswp__scroll-wrap">
|
||
<!-- Container that holds slides.
|
||
PhotoSwipe keeps only 3 of them in the DOM to save memory.
|
||
Don't modify these 3 pswp__item elements, data is added later on. -->
|
||
<div class="pswp__container">
|
||
<div class="pswp__item"></div>
|
||
<div class="pswp__item"></div>
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||
<div class="pswp__item"></div>
|
||
</div>
|
||
|
||
<!-- Default (PhotoSwipeUI_Default) interface on top of sliding area. Can be changed. -->
|
||
<div class="pswp__ui pswp__ui--hidden">
|
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|
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<!-- Controls are self-explanatory. Order can be changed. -->
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||
<div class="pswp__counter"></div>
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<button class="pswp__button pswp__button--close" title="Close (Esc)"></button>
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<button class="pswp__button pswp__button--share" title="Share"></button>
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<button class="pswp__button pswp__button--fs" title="Toggle fullscreen"></button>
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<button class="pswp__button pswp__button--zoom" title="Zoom in/out"></button>
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|
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|
||
<div class="pswp__preloader">
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||
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||
<div class="pswp__preloader__cut">
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||
<div class="pswp__preloader__donut"></div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
</div>
|
||
|
||
<div class="pswp__share-modal pswp__share-modal--hidden pswp__single-tap">
|
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<div class="pswp__share-tooltip"></div>
|
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</div>
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<button class="pswp__button pswp__button--arrow--left" title="Previous (arrow left)">
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</div>
|
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|
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<div class="figure-dialog-caption">
|
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<div class="figure-caption-link-container">
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<a class="figure-caption-link" href="#">See this image and copyright information in PMC</a>
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|
||
|
||
|
||
|
||
<div class="linked-articles" id="linked-updated-article">
|
||
<h2 class="title">
|
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Update of
|
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</h2>
|
||
<ul class="item-list usa-unstyled-list">
|
||
|
||
|
||
|
||
<li class="raw-citation">doi: 10.1002/14651858.CD013001</li>
|
||
|
||
|
||
</ul>
|
||
</div>
|
||
|
||
|
||
|
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|
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|
||
|
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<h2 class="title">
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References
|
||
</h2>
|
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<div id='top-references-list' class="references-lists-container">
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h4 class="refs-list-title">References to studies included in this review</h4>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Bamdad 2015 {published data only}</h5>
|
||
|
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|
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|
||
Bamdad S, Malekhosseini H, Khosravi A. Ultraviolet A/riboflavin collagen cross-linking for treatment of moderate bacterial corneal ulcers. Cornea 2015;34(4):402-6.
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-
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</div>
|
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|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Kasetsuwan 2016 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-3" class="references-list">
|
||
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<li>
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<ol class="references-and-notes-list">
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<li
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class="skip-numbering"
|
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value="1">
|
||
|
||
Kasetsuwan N, Reinprayoon U, Satitpitakul V. Photoactivated chromophore for moderate to severe infectious keratitis as an adjunct therapy: a randomized controlled trial. American Journal of Ophthalmology 2016;165:94-9.
|
||
|
||
|
||
|
||
-
|
||
<a
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class="reference-link"
|
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href="/26949133/"
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</li>
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</li>
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</ol>
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||
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||
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||
|
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</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Said 2014 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-4" class="references-list">
|
||
|
||
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||
|
||
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<li>
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<ol class="references-and-notes-list">
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<li
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class="skip-numbering"
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value="1">
|
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|
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Said DG, Elalfy MS, Gatzioufas Z, El-Zakzouk ES, Hassan MA, Saif MY, et al. Collagen cross-linking with photoactivated riboflavin (PACK-CXL) for the treatment of advanced infectious keratitis with corneal melting. Ophthalmology 2014;121(7):1377-82.
|
||
|
||
|
||
|
||
-
|
||
<a
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class="reference-link"
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href="/24576886/"
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ref="linksrc=references_link&ordinalpos=1"
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PubMed
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</li>
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</ol>
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</div>
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||
|
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</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h4 class="refs-list-title">References to studies excluded from this review</h4>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Abbouda 2016 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-6" class="references-list">
|
||
|
||
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||
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||
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||
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<li>
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<ol class="references-and-notes-list">
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||
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<li
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class="skip-numbering"
|
||
value="1">
|
||
|
||
Abbouda A, Abicca I, Alio JL. Infection keratitis following corneal crosslinking: a systematic review of reported cases: management, visual outcome, and treatment proposed. Seminars in Ophthalmology 2016;31(5):485-91.
|
||
|
||
|
||
|
||
-
|
||
<a
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class="reference-link"
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href="/25392046/"
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PubMed
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</li>
|
||
|
||
</ol>
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||
</li>
|
||
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||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Abbouda 2018 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-7" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
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<ol class="references-and-notes-list">
|
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<li
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||
class="skip-numbering"
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||
value="1">
|
||
|
||
Abbouda A, Abicca I, Alio JL. Current and future application of photoactivated chromophore for keratitis-corneal collagen cross-linking (PACK-CXL): an overview of the different treatments proposed. Seminars in Ophthalmology 2018;33(3):293-9.
|
||
|
||
|
||
|
||
-
|
||
<a
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class="reference-link"
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PubMed
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</ol>
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</div>
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|
||
<div class="refs-list">
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||
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||
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||
|
||
<h5 class="refs-list-title">Choi 2014 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-8" class="references-list">
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||
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||
|
||
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||
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||
|
||
<li>
|
||
<ol class="references-and-notes-list">
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||
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||
<li
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class="skip-numbering"
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||
value="1">
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||
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||
Choi KS, Yoon SC, Rim T, Han SJ, Kim ED, Seo KY. Effect of voriconazole and ultraviolet-A combination therapy compared to voriconazole single treatment on Fusarium solani fungal keratitis. Journal of Ocular Pharmacology and Therapeutics 2014;30(5):381-6.
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||
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||
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||
-
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||
<a
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class="reference-link"
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href="https://pmc.ncbi.nlm.nih.gov/articles/PMC4043359/"
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ref="linksrc=references_link&ordinalpos=1"
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||
data-ga-category="reference"
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||
data-ga-action="PMC4043359"
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||
>
|
||
PMC
|
||
</a>
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||
|
||
|
||
|
||
|
||
|
||
-
|
||
<a
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||
class="reference-link"
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||
href="/24724576/"
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||
ref="linksrc=references_link&ordinalpos=2"
|
||
data-ga-category="reference"
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||
data-ga-action="24724576"
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||
>
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||
PubMed
|
||
</a>
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||
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||
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||
|
||
|
||
</li>
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||
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||
</ol>
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||
</li>
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||
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|
||
</ol>
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||
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||
|
||
|
||
|
||
|
||
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||
|
||
|
||
</div>
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||
|
||
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||
<div class="refs-list">
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||
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||
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||
|
||
<h5 class="refs-list-title">CTRI/2015/07/006000 {published data only}</h5>
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||
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||
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||
|
||
|
||
|
||
<ol id="top-references-list-9" class="references-list">
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||
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||
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||
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||
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||
|
||
<li>
|
||
<ol class="references-and-notes-list">
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||
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||
<li
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||
class="skip-numbering"
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||
value="1">
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||
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||
CTRI/2015/07/006000. Pulse light accelerated crosslinking versus continuous accelerated crosslinking in microbial keratitis. <a class="external-link-urlize" href="http://ctri.nic.in/Clinicaltrials/pmaindet2.php?trialid=12084" rel="nofollow noopener" target="_blank">ctri.nic.in/Clinicaltrials/pmaindet2.php?trialid=12084</a> (first received 15 July 2015).
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||
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||
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||
</li>
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||
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||
</ol>
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||
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||
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||
|
||
</ol>
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||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
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||
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||
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||
|
||
<h5 class="refs-list-title">Ferrari 2013 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-10" class="references-list">
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||
|
||
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||
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||
|
||
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||
<li>
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||
<ol class="references-and-notes-list">
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||
<li
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||
class="skip-numbering"
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||
value="1">
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||
Ferrari G, Iuliano L, Vigano M, Rama P. Impending corneal perforation after corneal cross-linking for herpetic keratitis. Journal of Cataract and Refractive Surgery 2013;39(4):638-41.
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||
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||
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||
<a
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class="reference-link"
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href="/23522585/"
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||
ref="linksrc=references_link&ordinalpos=1"
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||
data-ga-category="reference"
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||
data-ga-action="23522585"
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||
>
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||
PubMed
|
||
</a>
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||
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||
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||
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||
|
||
</li>
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||
|
||
</ol>
|
||
</li>
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||
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||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Hafezi 2012 {published data only}</h5>
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||
|
||
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||
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||
|
||
|
||
<ol id="top-references-list-11" class="references-list">
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||
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||
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||
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||
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||
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||
<li>
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||
<ol class="references-and-notes-list">
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class="skip-numbering"
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value="1">
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||
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||
Hafezi F. Significant visual increase following infectious keratitis after collagen cross-linking. Journal of Refractive Surgery 2012;28(8):587-8.
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||
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||
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||
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||
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||
<a
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||
class="reference-link"
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||
href="/22785058/"
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||
ref="linksrc=references_link&ordinalpos=1"
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||
data-ga-category="reference"
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||
data-ga-action="22785058"
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||
>
|
||
PubMed
|
||
</a>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Hafezi 2014 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-12" class="references-list">
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||
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||
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||
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||
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||
|
||
<li>
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||
<ol class="references-and-notes-list">
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||
<li
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||
class="skip-numbering"
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||
value="1">
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||
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||
Hafezi F, Randleman JB. PACK-CXL: defining CXL for infectious keratitis. Journal of Refractive Surgery 2014;30(7):438-9.
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||
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||
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||
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||
-
|
||
<a
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||
class="reference-link"
|
||
href="/24983827/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
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||
data-ga-action="24983827"
|
||
>
|
||
PubMed
|
||
</a>
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||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Hafezi 2016 {published data only}</h5>
|
||
|
||
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||
|
||
|
||
|
||
<ol id="top-references-list-13" class="references-list">
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||
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||
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||
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||
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||
|
||
<li>
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||
<ol class="references-and-notes-list">
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<li
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||
class="skip-numbering"
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||
value="1">
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||
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||
Hafezi F, Kling S. Photoactivated chromophore for moderate to severe infectious keratitis as an adjunct therapy: a randomized controlled trial. American Journal of Ophthalmology 2016;168:293-4.
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||
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||
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||
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||
-
|
||
<a
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class="reference-link"
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||
href="/27292531/"
|
||
ref="linksrc=references_link&ordinalpos=1"
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||
data-ga-category="reference"
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||
data-ga-action="27292531"
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||
>
|
||
PubMed
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||
</a>
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||
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||
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||
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||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
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||
|
||
|
||
</ol>
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||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">IRCT2016112231028N1 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-14" class="references-list">
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||
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||
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||
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||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
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||
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||
<li
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||
class="skip-numbering"
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||
value="1">
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||
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||
IRCT2016112231028N1. Comparison of effects & complications of CCL surgery with 2 methods of epithelium removal & trans epithelial with using DAYA epithelium disruptor. <a class="external-link-urlize" href="http://en.irct.ir/trial/24481" rel="nofollow noopener" target="_blank">en.irct.ir/trial/24481</a> (first received 29 March 2017).
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||
|
||
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||
</li>
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||
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||
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||
</li>
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||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">ISRCTN21432643 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-15" class="references-list">
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||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
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||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
ISRCTN21432643. A clinical pilot study to evaluate collagen cross-linking (CXL) as a treatment for bacterial keratitis. <a class="external-link-urlize" href="http://isrctn.com/ISRCTN21432643" rel="nofollow noopener" target="_blank">isrctn.com/ISRCTN21432643</a> (first received 22 January 2010).
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||
|
||
|
||
</li>
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||
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||
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||
</li>
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||
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||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Letko 2011 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-16" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
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||
|
||
<li
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||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Letko E, Majmudar PA, Forstot SL, Epstein RJ, Rubinfeld RS. UVA-light and riboflavin-mediated corneal collagen cross-linking. International Ophthalmology Clinics 2011;51(2):63-76.
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||
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||
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||
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||
<a
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class="reference-link"
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href="/21383580/"
|
||
ref="linksrc=references_link&ordinalpos=1"
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||
data-ga-category="reference"
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||
data-ga-action="21383580"
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||
>
|
||
PubMed
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||
</a>
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||
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||
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
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||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Letsch 2015 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-17" class="references-list">
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||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
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||
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||
<li
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class="skip-numbering"
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||
value="1">
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||
|
||
Letsch J, Abou-Bacar A, Candolfi E, Bourcier T, Sauer A. Evaluation of in vitro efficacy of combined riboflavin and ultraviolet-A (365 nm) for Acanthamoeba [Efficacité anti-amibienne in vitro de l'association riboflavine/UV-A]. Journal Français d'Ophtalmologie 2015;38(3):213-9.
|
||
|
||
|
||
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||
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|
||
<a
|
||
class="reference-link"
|
||
href="/25637236/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="25637236"
|
||
>
|
||
PubMed
|
||
</a>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Li 2013 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-18" class="references-list">
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||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
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||
|
||
<li
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||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Li Z, Jhanji V, Tao X, Yu H, Chen W, Mu G. Riboflavin/ultraviolet light-mediated crosslinking for fungal keratitis. British Journal of Ophthalmology 2013;97(5):669-71.
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/23355529/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="23355529"
|
||
>
|
||
PubMed
|
||
</a>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Martinez 2018 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-19" class="references-list">
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||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
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||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Martinez J, Naranjo A, Amescua G, Dubovy S, Arboleda A, Durkee H, et al. Human corneal changes after rose bengal photodynamic antimicrobial therapy for treatment of fungal keratitis. Cornea 2018;37(10):e46-8.
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||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="https://pmc.ncbi.nlm.nih.gov/articles/PMC6131034/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="PMC6131034"
|
||
>
|
||
PMC
|
||
</a>
|
||
|
||
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/30028750/"
|
||
ref="linksrc=references_link&ordinalpos=2"
|
||
data-ga-category="reference"
|
||
data-ga-action="30028750"
|
||
>
|
||
PubMed
|
||
</a>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">NCT01464268 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-20" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
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||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
NCT01464268. Transepithelial corneal collagen crosslinking for keratoconus and corneal ectasia. <a class="external-link-urlize" href="http://clinicaltrials.gov/ct2/show/NCT01464268" rel="nofollow noopener" target="_blank">clinicaltrials.gov/ct2/show/NCT01464268</a> (first received 3 November 2011).
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
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||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">NCT02349165 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-21" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
NCT02349165. Standard versus transepithelial corneal crosslinking. <a class="external-link-urlize" href="http://clinicaltrials.gov/ct2/show/record/NCT02349165" rel="nofollow noopener" target="_blank">clinicaltrials.gov/ct2/show/record/NCT02349165</a> (first received 28 January 2015).
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">NCT02863809 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-22" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
NCT02863809. Vision restoration with a collagen crosslinked Boston keratoprosthesis unit. <a class="external-link-urlize" href="http://clinicaltrials.gov/ct2/show/NCT02863809" rel="nofollow noopener" target="_blank">clinicaltrials.gov/ct2/show/NCT02863809</a> (first received 11 August 2016).
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">NCT03041883 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-23" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
NCT03041883. Corneal collagen crosslinking to increase the resistance of the support graft of the KPro Type I against corneal melting. <a class="external-link-urlize" href="http://clinicaltrials.gov/ct2/show/record/NCT03041883" rel="nofollow noopener" target="_blank">clinicaltrials.gov/ct2/show/record/NCT03041883</a> (first received 3 February 2017).
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">NCT03138785 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-24" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
NCT03138785. UVX as an adjuvant in the treatment of fungal keratitis. <a class="external-link-urlize" href="http://clinicaltrials.gov/ct2/show/record/NCT03138785" rel="nofollow noopener" target="_blank">clinicaltrials.gov/ct2/show/record/NCT03138785</a> (first received 3 May 2017).
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">NCT03801590 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-25" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
NCT03801590. Crosslinking in infectious keratitis. <a class="external-link-urlize" href="http://clinicaltrials.gov/ct2/show/record/NCT03801590" rel="nofollow noopener" target="_blank">clinicaltrials.gov/ct2/show/record/NCT03801590</a> (first received 11 January 2019).
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">NCT03918408 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-26" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
NCT03918408. Safety and effectiveness of the PXL-Platinum 330 system for corneal collagen cross-linking in eyes with corneal thinning conditions. <a class="external-link-urlize" href="http://clinicaltrials.gov/ct2/show/NCT03918408" rel="nofollow noopener" target="_blank">clinicaltrials.gov/ct2/show/NCT03918408</a> (first received 17 April 2019).
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Poli 2013 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-27" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Poli M, Cornut PL, Balmitgere T, Aptel F, Janin H, Burillon C. Prospective study of corneal collagen cross-linking efficacy and tolerance in the treatment of keratoconus and corneal ectasia: 3-year results. Cornea 2013;32(5):583-90.
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/23086357/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="23086357"
|
||
>
|
||
PubMed
|
||
</a>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Price 2013 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-28" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Price MO, Tenkman LR, Schrier A, Fairchild K, Trokel S, Price F. Photoactivated riboflavin treatment of infectious keratitis using collagen cross-linking technology. Journal of Refractive Surgery 2012;28(10):706-13.
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/23062001/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="23062001"
|
||
>
|
||
PubMed
|
||
</a>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Rapuano 2017 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-29" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Rapuano PB, Scanameo AH, Amponin DE, Paulose SA, Zyablitskaya M, Takaoka A, et al. Antimicrobial studies using the therapeutic tissue cross-linking agent, sodium hydroxymethylglycinate: implication for treating infectious keratitis. Cornea 2017;59(1):332-7.
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="https://pmc.ncbi.nlm.nih.gov/articles/PMC5774256/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="PMC5774256"
|
||
>
|
||
PMC
|
||
</a>
|
||
|
||
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/29346493/"
|
||
ref="linksrc=references_link&ordinalpos=2"
|
||
data-ga-category="reference"
|
||
data-ga-action="29346493"
|
||
>
|
||
PubMed
|
||
</a>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Stulting 2012 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-30" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Stulting RD. Corneal collagen cross-linking. American Journal of Ophthalmology 2012;154(3):423-4.
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/22898341/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="22898341"
|
||
>
|
||
PubMed
|
||
</a>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Titiyal 2018 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-31" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Titiyal JS, Karunakaran A, Kaur M, Rathi A, Agarwal T, Sharma N. Collagen cross-linked therapeutic grafts in fungal keratitis. Ophthalmology 2018;125:1471-2.
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/29739628/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="29739628"
|
||
>
|
||
PubMed
|
||
</a>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Tzamalis 2019 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-32" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Tzamalis A, Romano V, Cheeseman R, Vinciguerra R, Batterbury M, Willoughby C, et al. Bandage contact lens and topical steroids are risk factors for the development of microbial keratitis after epithelium-off CXL. BMJ Open Ophthalmology 2019;4:1-7.
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="https://pmc.ncbi.nlm.nih.gov/articles/PMC6440609/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="PMC6440609"
|
||
>
|
||
PMC
|
||
</a>
|
||
|
||
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/30997402/"
|
||
ref="linksrc=references_link&ordinalpos=2"
|
||
data-ga-category="reference"
|
||
data-ga-action="30997402"
|
||
>
|
||
PubMed
|
||
</a>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Uddaraju 2015 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-33" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Uddaraju M, Mascarenhas J, Mano Ranjan D, Radhakrishnan N, Keenan JD, Prajna L, et al. Corneal cross-linking as an adjuvant therapy in the management of recalcitrant deep stromal fungal keratitis: a randomized trial. American Journal of Ophthalmology 2015;160(1):131-4.
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/25841317/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="25841317"
|
||
>
|
||
PubMed
|
||
</a>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">UMIN000006530 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-34" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
UMIN000006530. Usefulness of corneal cross-linking. <a class="external-link-urlize" href="http://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000007740" rel="nofollow noopener" target="_blank">upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000007740</a> (first received 12 October 2011).
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">UMIN000011350 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-35" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
UMIN000011350. Efficacy and safety of corneal collagen cross-linking for keratoconus, keratectasia and infectious keratitis. <a class="external-link-urlize" href="http://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000013299" rel="nofollow noopener" target="_blank">upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000013299</a> (first received 2 August 2013).
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">UMIN000023530 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-36" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
UMIN000023530. Corneal crosslinking for severe infectious corneal ulcers. <a class="external-link-urlize" href="http://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000027101" rel="nofollow noopener" target="_blank">upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000027101</a> (first received 7 August 2016).
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">UMIN000029466 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-37" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
UMIN000029466. Investigation of usefulness of high speed crosslinking using the topography guide Mosaic system. <a class="external-link-urlize" href="http://upload.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000033669" rel="nofollow noopener" target="_blank">upload.umin.ac.jp/cgi-open-bin/icdr_e/ctr_view.cgi?recptno=R000033669</a> (first received 7 October 2017).
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Vinciguerra 2013 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-38" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Vinciguerra R, Rosetta P, Romano MR, Azzolini C, Vinciguerra P. Treatment of refractory infectious keratitis with corneal collagen cross-linking window absorption. Cornea 2013;32(6):e139-40.
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/23572132/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="23572132"
|
||
>
|
||
PubMed
|
||
</a>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Wei 2019 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-39" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Wei A, Wang K, Wang Y, Gong L, Xu J, Shao T. Evaluation of corneal cross-linking as adjuvant therapy for the management of fungal keratitis. Graefe's Archive for Clinical and Experimental Ophthalmology 2019;257(7):1443-52.
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/31041523/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="31041523"
|
||
>
|
||
PubMed
|
||
</a>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">Zhang 2013 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-40" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Zhang ZY, Zhang XR. Evaluation of combined riboflavin and ultraviolet A as an alternative treatment for keratitis. Graefe's Archive for Clinical and Experimental Ophthalmology 2013;251(3):995-6.
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/22331148/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="22331148"
|
||
>
|
||
PubMed
|
||
</a>
|
||
|
||
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h4 class="refs-list-title">References to studies awaiting assessment</h4>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">NCT02088970 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-42" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
NCT02088970. Safety and efficacy of corneal collagen crosslinking in infectious keratitis. <a class="external-link-urlize" href="http://clinicaltrials.gov/ct2/show/record/NCT02088970" rel="nofollow noopener" target="_blank">clinicaltrials.gov/ct2/show/record/NCT02088970</a> (first received 17 March 2014).
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">NCT02865876 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-43" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
NCT02865876. Effectiveness of corneal accelerated crosslinking for infectious keratitis. <a class="external-link-urlize" href="http://clinicaltrials.gov/ct2/show/NCT02865876" rel="nofollow noopener" target="_blank">clinicaltrials.gov/ct2/show/NCT02865876</a> (first received 15 August 2016).
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">PACTR201701001843366 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-44" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
PACTR201701001843366. Corneal collagen cross linking for treatment of infectious keratitis. <a class="external-link-urlize" href="http://pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=1843" rel="nofollow noopener" target="_blank">pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=1843</a> (first received 30 October 2016).
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h4 class="refs-list-title">References to ongoing studies</h4>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">ACTRN12611000189921 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-46" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
ACTRN12611000189921. Corneal collagen cross-linking (CXL) as an adjunct in the treatment of microbial keratitis. <a class="external-link-urlize" href="http://anzctr.org.au/Trial/Registration/TrialReview.aspx?id=336545" rel="nofollow noopener" target="_blank">anzctr.org.au/Trial/Registration/TrialReview.aspx?id=336545</a> (first received 17 February 2011).
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">CTRI/2019/01/017136 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-47" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
CTRI/2019/01/017136. Steroids and cross-linking for ulcer treatment (SCUT II). <a class="external-link-urlize" href="http://ctri.nic.in/Clinicaltrials/pmaindet2.php?trialid=30685&EncHid=&userName=017136" rel="nofollow noopener" target="_blank">ctri.nic.in/Clinicaltrials/pmaindet2.php?trialid=30685&EncHid=&userName=...</a> (first received 17 January 2019).
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">CTRI/2019/02/017601 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-48" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
CTRI/2019/02/017601. Collagen cross linking as adjunctive treatment for corneal ulcer. <a class="external-link-urlize" href="http://ctri.nic.in/Clinicaltrials/pmaindet2.php?trialid=22937&EncHid=&userName=17601" rel="nofollow noopener" target="_blank">ctri.nic.in/Clinicaltrials/pmaindet2.php?trialid=22937&EncHid=&userName=...</a> (first received 12 February 2019).
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">NCT02570321 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-49" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
NCT02570321. Cross-linking for corneal ulcers treatment trial (CLAIR). <a class="external-link-urlize" href="http://clinicaltrials.gov/ct2/show/record/NCT02570321" rel="nofollow noopener" target="_blank">clinicaltrials.gov/ct2/show/record/NCT02570321</a> (first received 7 October 2015).
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">NCT02717871 {published data only}</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-50" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
NCT02717871. Swiss PACK-CXL multicenter trial for the treatment of infectious keratitis. <a class="external-link-urlize" href="http://clinicaltrials.gov/ct2/show/record/NCT02717871" rel="nofollow noopener" target="_blank">clinicaltrials.gov/ct2/show/record/NCT02717871</a> (first received 24 March 2016).
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h4 class="refs-list-title">Additional references</h4>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">AAO 2013</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-52" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
American Academy of Ophthalmology Cornea/External Disease Panel. Preferred Practice Pattern Guidelines. Bacterial keratitis. <a class="external-link-urlize" href="http://www.aao.org/ppp" rel="nofollow noopener" target="_blank">www.aao.org/ppp</a> (accessed 12 February 2018).
|
||
|
||
|
||
</li>
|
||
|
||
</ol>
|
||
</li>
|
||
|
||
|
||
</ol>
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
|
||
</div>
|
||
|
||
|
||
<div class="refs-list">
|
||
|
||
|
||
|
||
<h5 class="refs-list-title">AAO 2019</h5>
|
||
|
||
|
||
|
||
|
||
|
||
<ol id="top-references-list-53" class="references-list">
|
||
|
||
|
||
|
||
|
||
|
||
<li>
|
||
<ol class="references-and-notes-list">
|
||
|
||
<li
|
||
class="skip-numbering"
|
||
value="1">
|
||
|
||
Lin A, Rhee MK, Akpek EK, Amescua G, Farid M, Garcia-Ferrer FJ, et al. Bacterial keratitis preferred practice pattern®. Ophthalmology 2019;126(1):1-55.
|
||
|
||
|
||
|
||
-
|
||
<a
|
||
class="reference-link"
|
||
href="/30366799/"
|
||
ref="linksrc=references_link&ordinalpos=1"
|
||
data-ga-category="reference"
|
||
data-ga-action="30366799"
|
||
>
|
||
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<h4 class="refs-list-title">References to other published versions of this review</h4>
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|
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<div class="refs-list">
|
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|
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<h5 class="refs-list-title">Copeland 2018</h5>
|
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<li>
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<ol class="references-and-notes-list">
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<li
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class="skip-numbering"
|
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value="1">
|
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|
||
Copeland RA Jr, Davis SA, Lee YJ, Kwagyan J, Bovelle R. Corneal collagen cross-linking for infectious keratitis. Cochrane Database of Systematic Reviews 2018, Issue 5. [DOI: 10.1002/14651858.CD013001]
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|
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-
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<a
|
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class="reference-link"
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href="https://doi.org/10.1002/14651858.cd013001"
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DOI
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</a>
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-
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<a
|
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class="reference-link"
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href="https://pmc.ncbi.nlm.nih.gov/articles/PMC7389372/"
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PMC
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-
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<a
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PubMed
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</ol>
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</div>
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<div id="publication-types" class="publication-types keywords-section">
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<h2 class="title">
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Publication types
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data-pinger-ignore>
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<div id="mesh-terms" class="mesh-terms keywords-section">
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<h2 class="title">
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Keratitis/drug therapy"[MeSH]"
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data-ga-action="mesh_term"
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Search in PubMed
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</a></li><li><a class="search-in-mesh-link dropdown-block-link"
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href="https://www.ncbi.nlm.nih.gov/mesh?term=Keratitis"
|
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Search in MeSH
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</a></li><li><a class="add-to-search-link dropdown-block-link"
|
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data-search-term=""Keratitis/drug therapy"[MeSH]"
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data-ga-category="search"
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data-ga-label=""Keratitis/drug therapy"[MeSH]"
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Add to Search
|
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
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aria-label="Toggle dropdown menu for keyword Keratitis / microbiology"
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tabindex="0"
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aria-expanded="false"
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data-pinger-ignore>
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Keratitis / microbiology
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</button><div id="keyword-actions-mesh-terms-6"
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class="keyword-actions-dropdown dropdown dropdown-container"
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hidden
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aria-label="Dropdown menu for keyword Keratitis / microbiology"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
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href="/?term=%22Keratitis%2Fmicrobiology%22%5BMeSH%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Keratitis%2Fmicrobiology%22%5BMeSH%5D&sort=date&sort_order=desc"
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Keratitis/microbiology"[MeSH]"
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Search in PubMed
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</a></li><li><a class="search-in-mesh-link dropdown-block-link"
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Search in MeSH
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</a></li><li><a class="add-to-search-link dropdown-block-link"
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data-search-term=""Keratitis/microbiology"[MeSH]"
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Add to Search
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link major"
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aria-label="Toggle dropdown menu for keyword Keratitis / radiotherapy*"
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tabindex="0"
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aria-expanded="false"
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data-pinger-ignore>
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Keratitis / radiotherapy*
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</button><div id="keyword-actions-mesh-terms-major-7"
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class="keyword-actions-dropdown dropdown dropdown-container"
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hidden
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aria-label="Dropdown menu for keyword Keratitis / radiotherapy*"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
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href="/?term=%22Keratitis%2Fradiotherapy%22%5BMAJR%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Keratitis%2Fradiotherapy%22%5BMAJR%5D&sort=date&sort_order=desc"
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Keratitis/radiotherapy"[MAJR]"
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Search in PubMed
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</a></li><li><a class="search-in-mesh-link dropdown-block-link"
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</a></li><li><a class="add-to-search-link dropdown-block-link"
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data-search-term=""Keratitis/radiotherapy"[MAJR]"
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Add to Search
|
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link major"
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aria-label="Toggle dropdown menu for keyword Photosensitizing Agents / therapeutic use*"
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Photosensitizing Agents / therapeutic use*
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</button><div id="keyword-actions-mesh-terms-major-8"
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hidden
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aria-label="Dropdown menu for keyword Photosensitizing Agents / therapeutic use*"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
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href="/?term=%22Photosensitizing+Agents%2Ftherapeutic+use%22%5BMAJR%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Photosensitizing+Agents%2Ftherapeutic+use%22%5BMAJR%5D&sort=date&sort_order=desc"
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Photosensitizing Agents/therapeutic use"[MAJR]"
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data-search-term=""Photosensitizing Agents/therapeutic use"[MAJR]"
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Add to Search
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
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aria-label="Toggle dropdown menu for keyword Randomized Controlled Trials as Topic"
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Randomized Controlled Trials as Topic
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hidden
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aria-label="Dropdown menu for keyword Randomized Controlled Trials as Topic"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
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data-href="/?term=%22Randomized+Controlled+Trials+as+Topic%22%5BMeSH%5D&sort=date&sort_order=desc"
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link major"
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aria-label="Toggle dropdown menu for keyword Riboflavin / therapeutic use*"
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Riboflavin / therapeutic use*
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aria-label="Dropdown menu for keyword Riboflavin / therapeutic use*"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
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href="/?term=%22Riboflavin%2Ftherapeutic+use%22%5BMAJR%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Riboflavin%2Ftherapeutic+use%22%5BMAJR%5D&sort=date&sort_order=desc"
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Riboflavin/therapeutic use"[MAJR]"
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Search in PubMed
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Search in MeSH
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Add to Search
|
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
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aria-label="Toggle dropdown menu for keyword Ultraviolet Therapy / adverse effects"
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aria-expanded="false"
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data-pinger-ignore>
|
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Ultraviolet Therapy / adverse effects
|
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</button><div id="keyword-actions-mesh-terms-11"
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class="keyword-actions-dropdown dropdown dropdown-container"
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hidden
|
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aria-label="Dropdown menu for keyword Ultraviolet Therapy / adverse effects"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
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href="/?term=%22Ultraviolet+Therapy%2Fadverse+effects%22%5BMeSH%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Ultraviolet+Therapy%2Fadverse+effects%22%5BMeSH%5D&sort=date&sort_order=desc"
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Ultraviolet Therapy/adverse effects"[MeSH]"
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Search in PubMed
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Search in MeSH
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</a></li><li><a class="add-to-search-link dropdown-block-link"
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data-search-term=""Ultraviolet Therapy/adverse effects"[MeSH]"
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data-ga-category="search"
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Add to Search
|
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link major"
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aria-label="Toggle dropdown menu for keyword Ultraviolet Therapy / methods*"
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tabindex="0"
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aria-expanded="false"
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data-pinger-ignore>
|
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Ultraviolet Therapy / methods*
|
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</button><div id="keyword-actions-mesh-terms-major-12"
|
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class="keyword-actions-dropdown dropdown dropdown-container"
|
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hidden
|
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aria-label="Dropdown menu for keyword Ultraviolet Therapy / methods*"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
|
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href="/?term=%22Ultraviolet+Therapy%2Fmethods%22%5BMAJR%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Ultraviolet+Therapy%2Fmethods%22%5BMAJR%5D&sort=date&sort_order=desc"
|
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Ultraviolet Therapy/methods"[MAJR]"
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Search in PubMed
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data-ga-label="Ultraviolet Therapy / methods*">
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Search in MeSH
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</a></li><li><a class="add-to-search-link dropdown-block-link"
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ref="linksrc=add_to_search_link"
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role="button"
|
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data-search-term=""Ultraviolet Therapy/methods"[MAJR]"
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data-ga-category="search"
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data-ga-action="add_to_search"
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data-ga-label=""Ultraviolet Therapy/methods"[MAJR]"
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Add to Search
|
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
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aria-label="Toggle dropdown menu for keyword Visual Acuity"
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tabindex="0"
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aria-expanded="false"
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data-pinger-ignore>
|
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Visual Acuity
|
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</button><div id="keyword-actions-mesh-terms-13"
|
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class="keyword-actions-dropdown dropdown dropdown-container"
|
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hidden
|
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aria-label="Dropdown menu for keyword Visual Acuity"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
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href="/?term=%22Visual+Acuity%22%5BMeSH%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Visual+Acuity%22%5BMeSH%5D&sort=date&sort_order=desc"
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ref="linksrc=search_in_pubmed_keyword_link&mesh="Visual Acuity"[MeSH]"
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Search in PubMed
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</a></li><li><a class="search-in-mesh-link dropdown-block-link"
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href="https://www.ncbi.nlm.nih.gov/mesh?term=Visual+Acuity"
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Search in MeSH
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</a></li><li><a class="add-to-search-link dropdown-block-link"
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data-search-term=""Visual Acuity"[MeSH]"
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Add to Search
|
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</a></li></ul></div></div></div></li></ul>
|
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</div>
|
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|
||
|
||
|
||
|
||
|
||
<div id="substances" class="substances keywords-section">
|
||
<h2 class="title">
|
||
Substances
|
||
</h2>
|
||
|
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<ul class="keywords-list"><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
|
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aria-label="Toggle dropdown menu for keyword Anti-Bacterial Agents"
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tabindex="0"
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aria-controls="keyword-actions-substances-0"
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aria-expanded="false"
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data-pinger-ignore>
|
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Anti-Bacterial Agents
|
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</button><div id="keyword-actions-substances-0"
|
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class="keyword-actions-dropdown dropdown dropdown-container"
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hidden
|
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aria-label="Dropdown menu for keyword Anti-Bacterial Agents"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
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href="/?term=%22Anti-Bacterial+Agents%22%5Bnm%5D&sort=date&sort_order=desc"
|
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data-href="/?term=%22Anti-Bacterial+Agents%22%5Bnm%5D&sort=date&sort_order=desc"
|
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ref="linksrc=search_in_pubmed_keyword_link&keyword="Anti-Bacterial Agents"[nm]"
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data-ga-action="substance"
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data-ga-label="Anti-Bacterial Agents">
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Search in PubMed
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</a></li><li><a class="search-in-mesh-link dropdown-block-link"
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href="https://www.ncbi.nlm.nih.gov/mesh?term=%22Anti-Bacterial+Agents%22"
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data-ga-action="substance_link"
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data-ga-label="Anti-Bacterial Agents">
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Search in MeSH
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</a></li><li><a class="add-to-search-link dropdown-block-link"
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ref="linksrc=add_to_search_link"
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data-search-term=""Anti-Bacterial Agents"[nm]"
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data-ga-category="search"
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data-ga-action="add_to_search"
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data-ga-label=""Anti-Bacterial Agents"[nm]"
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Add to Search
|
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</a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link"
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aria-label="Toggle dropdown menu for keyword Photosensitizing Agents"
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tabindex="0"
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|
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aria-expanded="false"
|
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data-pinger-ignore>
|
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Photosensitizing Agents
|
||
</button><div id="keyword-actions-substances-1"
|
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class="keyword-actions-dropdown dropdown dropdown-container"
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hidden
|
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aria-label="Dropdown menu for keyword Photosensitizing Agents"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link"
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href="/?term=%22Photosensitizing+Agents%22%5Bnm%5D&sort=date&sort_order=desc"
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data-href="/?term=%22Photosensitizing+Agents%22%5Bnm%5D&sort=date&sort_order=desc"
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ref="linksrc=search_in_pubmed_keyword_link&keyword="Photosensitizing Agents"[nm]"
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data-ga-action="substance"
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Search in PubMed
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</a></li><li><a class="search-in-mesh-link dropdown-block-link"
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href="https://www.ncbi.nlm.nih.gov/mesh?term=%22Photosensitizing+Agents%22"
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