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{"id":10963,"date":"2023-03-16T11:32:59","date_gmt":"2023-03-16T15:32:59","guid":{"rendered":"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/?p=10963"},"modified":"2024-01-29T14:25:50","modified_gmt":"2024-01-29T19:25:50","slug":"homologene-datasets","status":"publish","type":"post","link":"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2023\/03\/16\/homologene-datasets\/","title":{"rendered":"New Way to View and Download Related Genes"},"content":{"rendered":"<h3><em>Effective June 2023, the HomoloGene records will redirect to the Datasets Gene Table<br \/>\n<\/em><\/h3>\n<div class=\"wptb-table-container wptb-table-12740\"><div class=\"wptb-table-container-matrix\" id=\"wptb-table-id-12740\" data-wptb-version=\"2.0.2\" data-wptb-pro-status=\"false\"><table class=\"wptb-preview-table wptb-element-main-table_setting-12740\" data-reconstraction=\"1\" style=\"border: 3px solid rgb(0, 0, 0);\" data-wptb-table-tds-sum-max-width=\"136\" data-wptb-cells-width-auto-count=\"1\" data-wptb-horizontal-scroll-status=\"false\" data-wptb-extra-styles=\"LyogRW50ZXIgeW91ciBjdXN0b20gQ1NTIHJ1bGVzIGhlcmUgKi8=\" role=\"table\" data-table-columns=\"1\"><tbody><tr class=\"wptb-row\"><td class=\"wptb-cell\" data-y-index=\"0\" data-x-index=\"0\" style=\"border: 1px solid rgb(0, 0, 0);\" data-wptb-css-td-auto-width=\"true\"><div class=\"wptb-text-container wptb-ph-element wptb-element-text-597\" style=\"color: rgb(0, 0, 0); font-size: 20px;\"><div class=\"\" style=\"position: relative;\"><p><strong>Important Note<\/strong>: The redirect from HomoloGene to NCBI Datasets is delayed until the beginning of 2024.<\/p><\/div><\/div><\/td><\/tr><\/tbody><\/table><\/div><\/div>\n\n<p><span data-contrast=\"none\">Do you use <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/homologene?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=homologene-datasets-20230316\" target=\"_blank\" rel=\"noopener\">HomoloGene<\/a> to view and download data? You can now access updated homology data from <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=homologene-datasets-20230316\">NCBI Datasets<\/a> through the <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/data-hub\/gene\/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=homologene-datasets-20230316\">Datasets Gene Table<\/a> with connections to <a href=\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2019\/04\/24\/searching-for-orthologous-genes-at-ncbi\/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=homologene-datasets-20230316\">NCBI Orthologs<\/a>. Go directly from a HomoloGene record to the Datasets Gene Table that will give you access to up-to-date sequence data and metadata.<\/span><span data-ccp-props=\"{"201341983":0,"335559739":0,"335559740":240}\"> NCBI Datasets is a new resource that lets you easily gather data from across NCBI databases.<\/span><\/p>\n<p><span data-contrast=\"none\">The Datasets Gene Table provides connections to the NCBI Ortholog interface (Figure 1) that provides the following data:<\/span><span data-ccp-props=\"{"201341983":0,"335559739":160,"335559740":259}\">\u00a0<\/span><\/p>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"1\" data-list-defn-props=\"{"335552541":1,"335559684":-2,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"\uf0b7","469777815":"multilevel"}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"none\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/kis\/info\/how-are-orthologs-calculated\/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=homologene-datasets-20230316\">Orthology data<\/a> based on an updated algorithm that identifies orthologs spanning > 500 vertebrate species<\/span><span data-ccp-props=\"{"201341983":0,"335559739":160,"335559740":240}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"1\" data-list-defn-props=\"{"335552541":1,"335559684":-2,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"\uf0b7","469777815":"multilevel"}\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"none\"><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/kis\/info\/how-are-similar-genes-calculated\/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=homologene-datasets-20230316\">Similar gene data<\/a> based on protein architectures that spans all eukaryotes<\/span><span data-ccp-props=\"{"201341983":0,"335559739":160,"335559740":240}\">\u00a0<\/span><\/li>\n<\/ul>\n<p><!--more--><\/p>\n<p><span data-contrast=\"none\">Click on the \u2018Datasets Gene Table\u2019 link on the new banner on our <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/homologene\/30951\/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=homologene-datasets-20230316\">HomoloGene record pages<\/a> to go to the <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/data-hub\/gene\/id\/1d224dca254d0b9dafeaa3bfb9c41fe8\/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=homologene-datasets-20230316\">Datasets Gene Table<\/a> interface.<\/span><span data-ccp-props=\"{"201341983":0,"335559739":0,"335559740":240}\">\u00a0<\/span><\/p>\n<p><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"10962\" data-permalink=\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/hg_datasets_orthologs_border\/\" data-orig-file=\"https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2023\/03\/Hg_Datasets_orthologs_border.png?fit=1233%2C1978&ssl=1\" data-orig-size=\"1233,1978\" data-comments-opened=\"1\" data-image-meta=\"{"aperture":"0","credit":"","camera":"","caption":"","created_timestamp":"0","copyright":"","focal_length":"0","iso":"0","shutter_speed":"0","title":"","orientation":"0"}\" data-image-title=\"Hg_Datasets_orthologs_border\" data-image-description=\"\" data-image-caption=\"\" data-medium-file=\"https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2023\/03\/Hg_Datasets_orthologs_border.png?fit=187%2C300&ssl=1\" data-large-file=\"https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2023\/03\/Hg_Datasets_orthologs_border.png?fit=638%2C1024&ssl=1\" class=\"alignright size-full wp-image-10962\" src=\"https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2023\/03\/Hg_Datasets_orthologs_border.png?resize=1108%2C1777&ssl=1\" alt=\"\" width=\"1108\" height=\"1777\" srcset=\"https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2023\/03\/Hg_Datasets_orthologs_border.png?w=1233&ssl=1 1233w, https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2023\/03\/Hg_Datasets_orthologs_border.png?resize=187%2C300&ssl=1 187w, https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2023\/03\/Hg_Datasets_orthologs_border.png?resize=638%2C1024&ssl=1 638w, https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2023\/03\/Hg_Datasets_orthologs_border.png?resize=94%2C150&ssl=1 94w, https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2023\/03\/Hg_Datasets_orthologs_border.png?resize=768%2C1232&ssl=1 768w, https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2023\/03\/Hg_Datasets_orthologs_border.png?resize=957%2C1536&ssl=1 957w, https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2023\/03\/Hg_Datasets_orthologs_border.png?resize=1200%2C1925&ssl=1 1200w, https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2023\/03\/Hg_Datasets_orthologs_border.png?resize=168%2C270&ssl=1 168w\" sizes=\"auto, (max-width: 1108px) 100vw, 1108px\" \/><\/p>\n<p><i><span data-contrast=\"none\">Figure 1.\u00a0 HomoloGene access to homology data in Datasets. You can link to the Datasets gene table for genes in the HomoloGene cluster. The Gene table provides a link to the NCBI Ortholog data providing expanded homology information that includes more genes and sequences for more species.<\/span><\/i><span data-ccp-props=\"{"201341983":0,"335559739":160,"335559740":259}\">\u00a0<\/span><\/p>\n<h4><b><span data-contrast=\"none\">Need ortholog data on the command-line?<\/span><\/b><span data-ccp-props=\"{"201341983":0,"335559739":160,"335559740":259}\">\u00a0<\/span><\/h4>\n<p><span data-contrast=\"none\">Use the datasets command-line tool to <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/datasets\/docs\/v2\/how-tos\/genes\/download-ortholog-dataset\/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=homologene-datasets-20230316\"><span data-contrast=\"none\">download an ortholog data package<\/span><\/a><span data-contrast=\"none\">.<\/span><span data-ccp-props=\"{"201341983":0,"335559739":160,"335559740":259}\">\u00a0<\/span><\/p>\n<h4><b><span data-contrast=\"none\">Questions?<\/span><\/b><span data-ccp-props=\"{"201341983":0,"335559739":160,"335559740":259}\">\u00a0<\/span><\/h4>\n<p><span data-contrast=\"none\">We encourage you to try this new way of exploring related genes. Let us know what you think! In June 2023, we will automatically redirect from HomoloGene records to the gene table.<\/span><span data-ccp-props=\"{"201341983":0,"335559739":160,"335559740":259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">If you have questions or would like to provide feedback, feel free to <\/span><a href=\"mailto:info@ncbi.nlm.nih.gov\"><span data-contrast=\"none\">reach out<\/span><\/a><span data-contrast=\"none\"> to us or use the Feedback button on any Datasets page.<\/span><span data-ccp-props=\"{"201341983":0,"335559739":0,"335559740":240}\">\u00a0<\/span><\/p>\n<h4><b><span data-contrast=\"auto\">Stay up to date<\/span><\/b><span data-ccp-props=\"{"201341983":0,"335559739":0,"335559740":240}\">\u00a0<\/span><\/h4>\n<p><span data-contrast=\"auto\">NCBI Datasets supports the\u202f<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/comparative-genomics-resource\/?utm_source=ncbi_insights&utm_medium=referral&utm_campaign=homologene-datasets-20230316\"><span data-contrast=\"none\">NIH Comparative Genomics Resource (CGR)<\/span><\/a><span data-contrast=\"auto\">, an NLM project to establish an ecosystem to facilitate reliable comparative genomics analyses\u202ffor all eukaryotic organisms.\u202f<\/span><a href=\"https:\/\/public.govdelivery.com\/accounts\/USNLMOCPL\/subscriber\/new?topic_id=USNLMOCPL_50%22\"><span data-contrast=\"none\">Join our mailing list<\/span><\/a><span data-contrast=\"auto\">\u202fto keep up to date with NCBI Datasets and other CGR news.\u202f<\/span><span data-ccp-props=\"{"201341983":0,"335559739":0,"335559740":240}\">\u00a0<\/span><\/p>\n<p> <\/p>\n<p> <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Effective June 2023, the HomoloGene records will redirect to the Datasets Gene Table Do you use HomoloGene to view and download data? You can now access updated homology data from NCBI Datasets through the Datasets Gene Table with connections to NCBI Orthologs. Go directly from a HomoloGene record to the Datasets Gene Table that will … <a href=\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2023\/03\/16\/homologene-datasets\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">New Way to View and Download Related Genes<\/span> <span class=\"meta-nav\">→<\/span><\/a><\/p>\n","protected":false},"author":42204617,"featured_media":10982,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"New Way to View and Download Related Genes","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","enabled":false},"version":2}},"categories":[2248],"tags":[693060768,693060686,9714,10594430],"table_tags":[],"class_list":["post-10963","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-whats-new","tag-comparative-genomics-resource-cgr","tag-datasets","tag-gene","tag-homologs"],"jetpack_publicize_connections":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>New Way to View and Download Related Genes - NCBI Insights<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2023\/03\/16\/homologene-datasets\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New Way to View and Download Related Genes - NCBI Insights\" \/>\n<meta property=\"og:description\" content=\"Effective June 2023, the HomoloGene records will redirect to the Datasets Gene Table Do you use HomoloGene to view and download data? You can now access updated homology data from NCBI Datasets through the Datasets Gene Table with connections to NCBI Orthologs. Go directly from a HomoloGene record to the Datasets Gene Table that will … Continue reading New Way to View and Download Related Genes →\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2023\/03\/16\/homologene-datasets\/\" \/>\n<meta property=\"og:site_name\" content=\"NCBI Insights\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/ncbi.nlm\" \/>\n<meta property=\"article:published_time\" content=\"2023-03-16T15:32:59+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-01-29T19:25:50+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2023\/03\/HomoloGene_Update-4-e1678980848655.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1100\" \/>\n\t<meta property=\"og:image:height\" content=\"575\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"NCBI Staff\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@NCBI\" \/>\n<meta name=\"twitter:site\" content=\"@NCBI\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"NCBI Staff\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2023\/03\/16\/homologene-datasets\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2023\/03\/16\/homologene-datasets\/\"},\"author\":{\"name\":\"NCBI Staff\",\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/#\/schema\/person\/4f41ea6a31cea38a9a1b1419c048e50b\"},\"headline\":\"New Way to View and Download Related Genes\",\"datePublished\":\"2023-03-16T15:32:59+00:00\",\"dateModified\":\"2024-01-29T19:25:50+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2023\/03\/16\/homologene-datasets\/\"},\"wordCount\":324,\"commentCount\":3,\"publisher\":{\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/#organization\"},\"image\":{\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2023\/03\/16\/homologene-datasets\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/i0.wp.com\/ncbiinsights.ncbi.nlm.nih.gov\/wp-content\/uploads\/2023\/03\/HomoloGene_Update-4-e1678980848655.png?fit=1100%2C575&ssl=1\",\"keywords\":[\"Comparative Genomics Resource (CGR)\",\"Datasets\",\"Gene\",\"Homologs\"],\"articleSection\":[\"What's New\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2023\/03\/16\/homologene-datasets\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2023\/03\/16\/homologene-datasets\/\",\"url\":\"https:\/\/ncbiinsights.ncbi.nlm.nih.gov\/2023\/03\/16\/homologene-datasets\/\",\"name\":\"New Way to View and Download Related Genes - 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You can now access updated homology data from NCBI Datasets through the Datasets Gene Table with connections to NCBI Orthologs. 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